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Echinacea: why does it work in real life but not in trials? - The Wellness Revolution Why clinical trials must take into account real dosage amounts! You took it, and it worked. You’re one of legions of people all over the world who have found the little purple coneflower called Echinacea to be wonderfully effective in fighting colds. Echinacea is among the most popular herbal supplements in North America, accounting for 10% of herbal sales in the U.S. So why are some in the scientific community saying it doesn’t work? How Controversy Over a Little Flower It was a July 2005 study done at the University of Edmonton in Canada, published in the pages of the New England Journal of Medicine, that fueled the fire of controversy. On one side, there’s the community of people who take Echinacea to ward off colds and other respiratory tract infections (staying well or getting better quickly tends to make enthusiastic and loyal followers). On the other side is a spate of studies, culminating in the July 2005, giving the thumbs down to the flower’s healing powers. The much-touted study was a placebo-controlled trial and was double-blinded (neither test group knew what they were taking). Healthy college students were given a dose of a rhinovirus infection, and were then sent to individual dorm rooms to take either an extract of Echinacea or a placebo. The results were disappointing to those of us expecting the scientific community’s “proof” to match ours—based on what our bodies and senses tell us. The study found no statistically significant difference between severity of symptoms or duration of the rhinovirus between the Echinacea and the control group. Why didn’t the study results match those of so many individuals? What went wrong? Noted herbalist and author Roy Upton states, [“The studies which found] positive results had dosages which were consistent with herbalist recommendations.”] The University of Edmonton study didn’t. Two oft-cited clinical trials in which positive results were found in ...

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