Glucosamine Sulfate 500

Glucosamine Sulfate 500 mg

...Helps maintain healthy joints*

Features & Benefits

• Helps ease aching and tenderness*

• Natural constituent of cartilage, crucial for a healthy skeletal system*

• Helps maintain cartilage in joints*

• Sodium free - potassium based

Facts About Glucosamine Sulfate

Joints are involved in every movement of your body. Joints are made of cartilage and synovial fluid which cushion movement, while ligaments, tendons and connective tissue hold your bones together. During your lifetime, joints receive a lot of stress. As we grow older, joints frequently are less flexible and may be prone to aches and pains.

Glucosamine sulfate is a natural constituent found in cartilage and synovial fluid.* It is a compound made from glucose (a sugar) and glutamine (an amino acid). Supplementing with glucosamine sulfate assures your body of a continuous supply of this building block of cartilage.*

Glucosamine helps proteins bond to water in cartilage and stimulates cartilage to make proteins called glycosaminoglycans* (proteoglycans.) Glucosamine sulfate also stimulates the production of cartilage cells called chondrocytes.* Studies show that glucosamine sulfate is very well absorbed.* Glucosamine levels in the blood reach a peak one hour after consumption and last for up to ten hours.*1

In one double-blinded study, 500 mg glucosamine sulfate, 3 times per day, reduced aches by 40%.*2 All of the people showed some improvement.* Several other double-blinded studies, using the same amount, produced similar results of less tenderness.*2, 3, 4, 5, 6 Meaningful improvement in joint movement and function occurred steadily during these studies.* In all of these studies, side effects were no greater with glucosamine sulfate than with the placebo (sugar pill).*

A clinical study of 1,500 people over a 9-month period reported that 95% of the people who took glucosamine sulfate showed significant improvement of their joint function.*6 Supplements of 1,500 mg per day were given for an average of 50 days. Very few people had any side effects, but some experienced heartburn.* The improvement lasted from six to twelve weeks after they stopped taking glucosamine sulfate.*

Ingredient Highlights

Nature's Life Glucosamine Sulfate 500 mg is sodium free. Since glucosamine sulfate is not stable, either sodium chloride or potassium chloride is added to protect this delicate compound. Nature's Life uses only potassium chloride as a stabilizer. Other brands may contain over 500 mg sodium chloride (table salt) in a daily dose. Different forms of glucosamine that do not contain sulfate, such as Glucosamine Hydrochloride (HCl) and N-Acetyl- Glucosamine (NAG) are not as well supported by research trials.

Safety of Glucosamine Sulfate

No adverse effects have been noted in numerous human studies using 1,500 mg of glucosamine sulfate daily.*1, 2, 3, 4, 5, 6 When dogs were fed 2,149 mg/kg/d (about 1 ounce per day for a 30 pound dog) of glucosamine sulfate every day for over a year, no toxic or ill effects were noted.*1

References

1. Nutrition Applied to Injury Rehabilitation and Sports Medicine, p195-203, CRC Press, Boca Raton, FL, 1995

2. Curr Med Res Opin 1980;7(2):110-14

3. Curr Med Res Opin 1982;8(3):145-9

4. Clin Ther 1980;3(4):260-72

5. Pharmatherapeutica 1981;2(8):504-8

6. Pharmatherapeutica 1982;3(3):157