Synergistic Glucosamine/MSM Formula
180 Capsules
As a
dietary supplement, each capsule contains:
Glucosamine sulfate
..............................................250mg
(sodium
free, contains 24-26% potassium chloride)
MSM
LIGNISUL.......................................................50
0mg
(methylsulfonylmethane)
Vitamin C
..............................................................50m
g
(ascorbic acid, corn free)
Excipient: Cellulose, magnesium
stearate
Suggested Adult Use: Two capsules, 3 times daily.
Ingredients
Synergistic Glucosamine/MSM Formula contains pure,
sodium-free, potassium-stabilized glucosamine sulfate, as
confirmed by HPLC testing.
Note: Glucosamine sulfate is derived
from the shells of ocean-growing shellfish. It is processed to
remove all residues of protein and impurities, yielding pure
glucosamine sulfate as the final material. Synergistic
Glucosamine/MSM Formula contains pure LIGNISUL™ MSM
(methylsulfonylmethane). LIGNISUL™ MSM is natural-source MSM
derived from trees. A biological compound that occurs in the
human body and in some foods, MSM is an excellent dietary source
of bioavailable organic sulfur. Synergistic Glucosamine/MSM
Formula contains pure, corn-free ascorbic
acid.
Benefits
Glucosamine sulfate supports joint function
by supplying the body with dietary ingredients (glucosamine and
sulfur) for building joint cartilage.* Glucosamine, an amino
sugar normally manufactured in cartilage, stimulates the
production of cartilage components known as
“glycosaminoglycans.”1 These substances are essential to the
maintenance of sound joint structure, which in turn allows for
normal joint function.
MSM, organic sulfur is a structural
mineral that maintains the strength of various tissues by
forming sulfur “tie-bars” (sulfhydryl bonds) between connective
tissue proteins. MSM supplies the body with nature’s original
source of organic bioavailable sulfur.
Vitamin C is essential
for the formation of collagen, the protein fiber that gives
cartilage its structural strength.*
MSM
MSM, organic sulfur
is a structural mineral that maintains the strength of various
tissues by forming sulfur “tie-bars” (sulfhydryl bonds) between
connective tissue proteins. MSM supplies the body with nature’s
original source of organic bioavailable sulfur.
Vitamin
C
Vitamin C is essential for the formation of collagen, the
protein fiber that gives cartilage its structural
strength.*
Why is potassium-stabilized glucosamine sulfate
preferable?
In order for glucosamine sulfate to be processed
for oral intake as a supplement, it must be stabilized with
either sodium or potassium. Either mineral works for this
purpose. Potassium is preferable. Many people are on
sodium-restricted diets, and the Standard American Diet tends to
be high in sodium and low in potassium. What’s more, studies
have found that people needing joint support are low in both
salivary potassium and total body potassium.2,3,4
Glucosamine
Sulfate: A solid foundation of clinical evidence
Glucosamine
sulfate has been thoroughly researched over the last 20 years.
Double-blind and open clinical trials convincingly demonstrate
that oral glucosamine sulfate improves joint function.5.6
In
one large open trial, more than 1,200 people took oral
glucosamine sulfate for periods ranging from 36 to 64 days. 252
physicians participated in this multi-center study. 95% of the
subjects experienced greater joint comfort and increased
mobility. The physicians reported “good” results in 59%, and
“sufficient” results in 36%. The improvements lasted for up to
three months after the glucosamine sulfate was
discontinued.6
Why the human body needs MSM
The human body
requires a continuous supply of bioavailable sulfur, and MSM is
one of the primary, organic, sulfur-containing molecules for use
by living organisms. MSM occurs normally in tissues and body
fluids. Scientists who have studied MSM in detail believe MSM is
an absolute requirement for maintenance of healthy tissues and
organ functions.7,8
The research on MSM has led to the filing
of several patents that cover numerous uses of MSM as a dietary
ingredient for both humans and animals.7 Through these studies,
it has been found that physical and psychological stress
increases in the body when its MSM supply falls below minimum
levels, resulting in a loss of normal organ function.7,8
MSM
supports joint and organ function by donating sulfur for
formation of sulfur tie-bars that maintain the integrity of
cartilage and other tissues.* Based on clinical observations,
MSM benefits the body in many ways, which include maintenance of
healthy skin, hair, and nails, digestive system support, and
immune support.* MSM is as nontoxic to the body as water, and is
therefore completely safe, even at high dosage
levels.7
Supplementation is Needed to Realize the Benefits of
MSM
Widespread in nature, MSM is found in a variety of foods,
including fresh fruits and vegetables, raw milk, raw meat and
raw fish.7,8 However, MSM is a volatile substance easily lost
during cooking, pasteurization, food processing and storage. The
average American diet thus supplies at best a marginal MSM
intake, which may be inadequate to maintain the optimum MSM
concentration in the body. The body’s MSM concentration is also
believed to decline with increasing age.8
* These statements
have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or
prevent any disease.
References
1. Vidal y Plana, R.R.,
Bizzarri, D., Rovati, A.L., “Articular cartilage pharmacology:
I. In vitro studies on glucosamine and non-steroidal
anti-inflammatory drugs.” Pharmacological Research
Communications 1978; 10(6):557-569.
2. Siamopoulou, A. et. al.
“Sialochemistry in juvenile chronic arthritis.” British Journal
of Rheumatology 1989;28(5):383-5.
3. Syrjanen, S. et. al.
“Salivary and serum levels of electrolytes and immunomarkers in
edentulous healthy subjects and in those with rheumatoid
arthritis.” Clinical Rheumatology 1986;5(1):49-55.
4. Sambrook,
P.N., et. al. “Bone turnover in early rheumatoid arthritis.” 1.
Biochemical and kinetic indexes. Annals of the Rheumatic
Diseases 1985;44(9):575-9.
5. Macario , J. T., Rivera, I.C.,
Bignamini, A.A., “Oral glucosamine sulfate in the management of
arthrosis: report on a multi-centre open investigation in
Portugal.” Pharmatherapeutica 1982; 3(3):157-68.
6. Vaz, A.L.,
“Double-blind clinical evaluation of the relative efficacy of
ibuprofen and glucosamine sulfate in the management of
osteoarthrosis of the knee in out-patients.” Current Medical
Research and Opinion 1982; 8(3):145-149.
7. Herschler, R.
“Methylsulfonylmethane in dietary products.” United States
Patent 4,616,039; Oct. 7, 1986.
8. Jacob, S., Herschler, R.
“Introductory remarks: dimethyl sulfoxide after 20 years.”
Annals of the New York Academy of Sciences 1983;
411:xiii-xvii.
9. Hardingham, T. “Proteoglycans: Their
structure, interactions and molecular organization in
cartilage.” Biochemical Society Transactions
1981;9(6):489-97.
10. Bland, J. H., Cooper, S.M.
“Osteoarthritis: A review of the cell biology involved and
evidence for reversibility. Management rationally related to
known genesis and pathophysiology.” Seminars in Arthritis and
Rheumatism 1984;14(2):106-133.
© 2003 Doctor's Best, Inc.
Revised 03/2003
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