Isopreme Bioactive Whey Protein Isolate from Ultimate Nutrition. Whey protein is a high quality, complete protein, with all the essential amino acids. Whey protein is also the richest known source of naturally occurring branched chain amino acids (leucine, isoleucine and valine). These are important for active individuals, individuals who exercise and professional athletes. Ultimate Nutrition's Isopreme Bioactive Whey Isolate is produced exclusively through a new and innovative technology, ColdPure ultrafiltration. ColdPure ultrafiltration isolates the native whey protein in a highly bioactive form using an advanced low temperature ultrafiltration process. ColdPure ultrafiltration produces a superior Bioactive whey that is non-denatured and contains the highest content of essential amino acids (EAA’s) and branched chain amino acids (BCAA’s).