Respect. It doesn't come easy. You have to earn it... By
gritting out rep after rep in the gym. In your quest for heroic
biceps, bowling-ball shoulders, and an extra wide back. Bottom
line: You have to make the most of every workout. That's where
3-XL comes in.
3-XL (formerly called CE-XL) is the most
advanced creatine ester formula developed. Engineered to deliver
more increases in muscular size and strength than anything
you've ever tried before. Within one week, you'll experience
greater muscular fullness, crush your current training plateaus,
and carry a "pump" around the gym that makes other guys seethe
with envy.
* Increase Muscular Strength, Size, and
Hardness
* Generate Increased Blood Flow and Muscular
Fullness
* Increase Muscle Cell Volumization
*
Maximize Total Power Output
* Enhance Muscle Fiber Recovery
Creatine Monohydrate: One of the most widely used
performance-enhancing supplements on the market, creatine has
been the subject of over 200 studies. These studies have shown
definite positive effects for muscle building, enhanced cellular
energy capacity, and reduced muscle fatigue. Beyond its
muscle-building and performance-enhancing effects, creatine has
been shown to increase fat loss and have positive effects on
overall health by reducing cholesterol and triglyceride levels
and improving blood-sugar metabolism.
One of the most
thoroughly tested dietary supplements overall, and perhaps the
most exhaustively tested sports nutrition ingredient outside of
carbohydrates, is creatine monohydrate. Until several studies
show that a different form of creatine is superior to creatine
monohydrate when it is directly compared to creatine
monohydrate, and that "superiority" is defined by significantly
greater increases in fat-free mass and/or muscular performance,
creatine monohydrate stands alone.
*Di-Creatine Malate: A
highly soluble creatine salt thought to provide a greater
increase in creatine bioavailability over regular creatine
monohydrate. Quite simply, this compound is creatine bound to
malic acid. Malic acid is a naturally occurring Krebs Cycle
intermediate, meaning that malic acid plays a crucial role in
our natural energy cycle. Malic acid, coupled with creatine, as
in Di-Creatine Malate, offers much greater ATP production over
conventional creatine monohydrate. In the body, malic
acid...
* Stimulates oxygen consumption by increasing
mitochondrial uptake of other substrates
* Is the only
metabolite of the Krebs Cycle that falls in concentration during
exhaustive physical activity
* Depletion has been linked to
physical exhaustion
* Supports the removal of components
that buildup under hypoxic conditions and inhibit ATP
production.
*Creatine Ethyl Ester or CEE is a membrane
permeable form of creatine that theoretically can enter the
cells without having to use the "typical" creatine transporter
molecules. Creatine Ethyl Ester HCL (CEE) is creatine
monohydrate with an ester attached. Esters are organic compounds
that are formed by esterification—the reaction of carboxylic
acid and alcohols. Users are reported to gain substantial
increases in strength and muscle mass, with none of the
gastrointestinal discomfort or water bloating normally
associated with the monohydrate form. Recommended dosages range
from as little as one to three grams per day with no "loading"
phase, as typically prescribed for the monohydrate form.
Creatine monohydrate is semi-lipopholic (which means it
inefficiently uses fat as a transport mechanism). The
esterification of substances increases their lipopholic
abilities, leading to the conclusion that esterified creatine
will use fat more efficiently to permeate the cell wall and have
greater benefits upon cellular function than creatine
monohydrate alone.
*Elemental Creatine Transporter Cofactors:
Sodium and ChlorideCreatine transporters, as stated above, also
localize in the intestines and thus are the "first line" of
creatine transport. Because of the not uncommon experience of
intestinal distress (loose stools, diarrhea) among a minority of
creatine users, especially during the loading phase, one wonders
whether optimizing creatine transport conditions within the gut
could make a distinctively positive difference.
Using animal
intestinal segments and cells, intestinal creatine transport has
recently been shown to have a critical requirement for a
specific ratio of sodium and chloride ions—a 2:1 ratio—and no
apparent requirement for potassium.
Because creatine
transporter proteins are sodium- and chloride-dependent
transporters, the provision of an optimal ratio of sodium and
chloride, but not at an amount posing a concern for
sodium-sensitive individuals, may foster greater gut
tolerability during loading or single high-dose creatine
monohydrate supplementation. Additionally, this transporter
cofactor ratio may push absorption to the theoretical maximum of
100% of an oral dose.
*Histidine is an amino acid found in
the proteins of all life forms. Although most L-histidine is
found in proteins, a small amount of free L-histidine does exist
in plants and fermented foods. The naturally occurring
dipeptides found in muscle, carnosine and anserine, are both
comprised of L-histidine and beta-alanine. At the very least, it
is a conditional essential amino acid for adults. That is, even
though L-histidine is synthesized in adult human tissues,
sufficient quantities may not be made to meet the physiological
requirements imposed by certain stress or disease
situations.
It is also interesting to note that histidine
alone increases nitric oxide (NO) 48% more than an equivalent
concentration of arginine. So the use of an arginine and
histidine mixture may be the most financially viable
NO-releasing combination on the market today.
*Di-Arginine
Malate is a novel compound featuring two molecules of L-arginine
bound to malic acid. Most available NO boosters offer only one
molecule of L-arginine bound to AKG. L-Arginine is thought to
increase nitric oxide production, leading to increased
vasodilation and potentially increased protein synthesis. The
positive effects of L-arginine on nitric oxide production are
well established, but there were no published studies regarding
arginine alpha-ketoglutarate and nitric oxide
production.
Di-Arginine Malate™ was created by combining
arginine with malic acid, a naturally occurring intermediate in
the Krebs Cycle. This bond makes much more sense because malic
acid is the only metabolite of the Krebs Cycle that falls in
concentration during exhaustive physical activity. Studies show
that malic acid stimulates oxygen consumption by increasing
mitochondrial uptake of other substrates, and it's also known to
support the removal of components that buildup under hypoxic
conditions and inhibit ATP production.
What is 3-XL?
3-XL is
an advanced Tri-STRENGTH Creatine Complex™, developed by the
researchers at iSatori, to help increase muscular size,
strength, and hardness.
How does 3-XL work?
3-XL is
engineered to improve the absorption and retention of creatine,
using a combination of three different creatines, including a
novel form of creatine ethyl ester hydrochloride. Creatine ethyl
ester, in combination with its bioactive agents, and a unique
delivery method called Accelerated Plasma Shuttle Technology™,
found only in 3-XL, will dramatically improve total muscular
output and increase muscle mass, strength, and hardness. For
those seeking the most advanced results possible with 3-XL,
iSatori's researchers also recommend using H+Blocker™, the new
beta-alanine/carnosine synthesizer, to maximize gains.
What
kind of results can I expect from using 3-XL?
Although it's
impossible to say exactly how much muscle size and strength each
person will gain from using 3-XL—obviously, as individuals
differ, so will results—it is not unheard of for individuals to
experience immediate strength gains, muscle fullness, and
noticeable lean body mass gains within the first five days. More
notably, though, unlike conventional creatine monohydrate alone,
which has to be "loaded" and then "cycled," 3-XL can be used
continuously, thereby allowing users to continue to experience
results for as long as they use the supplement.
What's inside
3-XL?
The combination of active compounds, found only in
3-XL, is called the Tri-STRENGTH Creatine Complex™. This is an
exclusive blend of creatine ethyl ester, creatine monohydrate,
and di-creatine malate, which are the most superior forms of
creatine substances available. To that, di-arginine malate was
added as a natural biological precursor for nitric oxide, to aid
in the delivery of creatine and improve blood flow. 3-XL also
contains a precise blend of histidine, carbohydrates, sodium,
and chloride to aid in the rapid transport of the nutrients into
the muscular plasma and enhance creatine absorption and storage
even higher.
Why is 3-XL better than regular creatine
monohydrate?
Keep in mind, 3-XL contains some creatine
monohydrate, along with di-creatine malate. However, using only
the purest esterfied form of creatine (creatine ethyl ester
hydrochloride), combined with these two other forms of creatine
in the Tri-STRENGTH Creatine Complex™, 3-XL is engineered to
improve the effects of creatine and eliminate all of the
unwanted, common "side effects" of conventional creatine forms.
In other words, with 3-XL, you can expect:
* Creatines to
transport faster and more efficiently (up to 10 times faster),
because of their lipopholic abilities, which allows them to use
fat more efficiently to permeate the cell wall and exert its
effects upon cellular function.
* No "loading" is required
because more of the creatine is absorbed, and the optimal dose
needs to be taken only once daily.
* Typically, creatine
ethyl ester works for most creatine "non-responders."
*
Virtually no water retention occurs outside of the target muscle
cells, thereby eliminating the infamous "creatine bloat."
How
do I take 3-XL for optimal results?
As the label recommends,
consume one serving (a single scoop) of Fruit Punch flavored
3-XL mixed with eight ounces of water, about 30 minutes
immediately following intense exercise or physical activity. On
non-training days, consume one serving following your morning or
afternoon meal. Remember, as with all supplements, "more is
better" is not always a good idea. 3-XL is engineered to work
with a single dose taken each day.
Do I need to "load" or
"cycle" 3-XL?
Loading is not necessary. Relative to cycling,
although there is no need to "cycle" 3-XL, as we recommend with
all supplements, it's suggested that users follow an eight- to
12-week "on" period followed by a two- to four-week "off"
period. It's always a good practice to cleanse the body and help
it respond more optimally to supplement usage again, once it's
resumed.
Can I take 3-XL with a creatine product?
No. It's
not necessary. However, for those seeking the most advanced
results possible with 3-XL, iSatori's researchers also recommend
using H+Blocker™, the new beta-alanine/carnosine synthesizer, to
maximize gains.
Are there any known side effects?
There are
no known negative side effects. In fact, the active compounds in
3-XL are produced in the body, are naturally found in small
amounts within meats such as beef, and have been tested in
animals and humans quite extensively with no adverse effects.
Remember, it's always a good idea to check with your doctor
first before starting any new diet or exercise plan. And please
read the label carefully before you begin use.
WARNING
Not
intended for individuals under the age of 18 unless instructed
by a doctor. Do not use this product if you are pregnant,
nursing, or contemplating pregnancy. If you, or your doctor,
have any questions about this product, please call
1-303-215-9174. Keep out of reach of
children.
References
Bendahan, D., et al.,
"Citrulline/Malate Promotes Aerobic Energy Production in Human
Exercising Muscle," Br J Sports Med 36.4 (2002) :
282-9.
Bosco, C., et al., "Effect of Oral Creatine
Supplementation on Jumping and Running Performance," Int J
Sports Med 18.5 (1997) : 369-72.
Callis, A., et al.,
"Activity of Citrulline Malate on Acid Base Balance and Blood
Ammonia and Amino Acid Levels. Study in the Animal and in Man,"
Arzneimittelforschung 41.6 (1991) : 660-3.
Demant, T.W., and
Rhodes, E.C., "Effects of Creatine Supplementation on Exercise
Performance," Sports Med 28.1 (1999) : 49-60.
Dunaev, V., et
al., "Effect of Malic Acid Salts on Physical Working Capacity
and its Restoration After Exhausting Muscular Work," Farmakol
Toksikol 51.3 (1988) : 21-5.
Engelhardt, M., et al.,
"Creatine Supplementation in Endurance Sports," Med Sci Sport
Exerc 30.7 (1998) : 1123-9.
Feldman, E.B., "Creatine: A
Dietary Supplement and Ergogenic Aid," Nutr Rev 57.2 (1999) :
45-50.
Greenhaff, P.L., "The Nutritional Biochemistry of
Creatine," J Nutr Biochem 8 (1997) : 610-8.
Kreider, R.B.,
"Creatine Supplementation: Analysis of Ergogenic Value, Medical
Safety, and Concerns," JEP Online 1.1 (1998).
Lemon, P., et
al., "Effect of Oral Creatine Supplementation on Energetic
During Repeated Maximal Muscle Contraction," Med Sci Sport Exerc
27 (1995) : S204.
Mujika, I., and Padilla, S., "Creatine
Supplementation as an Ergogenic Aid for Sports Performance in
Highly Trained Athletes: A Critical Review," Int J Sports Med
18.7 (1997) : 491-6.
Robertson, R.J., et al., "Blood Glucose
Extraction as a Mediator of Perceived Exertion During Prolonged
Exercise," Eur J Appl Physiol 61.1-2 (1990) : 100-5.
Russell,
I.J., et al., "Treatment of Fibromyalgia Syndrome with Super
Malic: a Randomized, Double Blind, Placebo Controlled, Crossover
Pilot Study," J Rheumatol 22.5 (1995) :953-8.
Stone, M.H., et
al., "Effects of In-Season (5 Weeks) Creatine and Pyruvate
Supplementation on Anaerobic Performance and Body Composition in
American Football Players," Int J Sport Nutr 9.2 (1999) :
146-65.
Tarnopolsky, M., and Martin, J., "Creatine
Monohydrate Increases Strength in Patients with Neuromuscular
Disease," Neurology 52.4 (1999) : 854-7.
Toler, S.M.,
"Creatine Is an Ergogen for Anaerobic Exercise," Nutr Rev 55.1.1
(1997) : 21-3.
Volek, J.S., et al., "Performance and Muscle
Fiber Adaptations to Creatine Supplementation and Heavy
Resistance Training," Med Sci Sports Exerc 31.8 (1999) :
1147-56.
Watanabea, A., et al., "Effects of Creatine on
Mental Fatigue and Cerebral Hemoglobin Oxygenation,"
Neuroscience Research 42.4 (2002) : 279-85.
These are the
testimonials.
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