2-in-1 Secretagogue Stack
Ultra powerful secretagogue complex
that stimulates the endogenous production of human growth
hormone (hGH) and elevates IGF-1 levels to dramatically
influence muscular growth and definition!
SecretaGAIN™- is
an exclusive product innovation that stimulates the endogenous
(from within) release of human growth hormone. Two highly
effective and powerful complexes increase the body’s production
of growth hormone and secretion of the ultra powerful IGF-1
(insulin-like growth factor-1) responsible for stimulating
myoblast proliferation, protein synthesis, fat metabolism, and
carbohydrate metabolism. This is the power complex that takes
your body to the next level of super growth, amazing power, and
ultra definition.
Growth Hormone, also known as
somatotropin, is a protein hormone synthesized and secreted by
cells called somatrophs in the anterior pituitary gland from
about 190 amino acids. It is a major hormone responsible for
growth and metabolism.
The major role of growth hormone in
stimulating body growth is to stimulate the liver and other
tissues to secrete IGF-1 (insulin-like growth factor-1). IGF-1
also stimulates both the differentiation and proliferation of
myoblasts. It also stimulates amino acid uptake and protein
synthesis in muscle and other tissues. IGF-1 is one of the most
potent anabolic hormones in the body!
Growth hormone and
IGF-1 have major roles in protein, fat and carbohydrate
metabolism. This is metabolically significant to the athlete in
that these hormones influence protein for growth, fatty acids
and body fat reduction, and carbohydrates for energy and
recovery. Growth hormone stimulates the anabolic amino acid
uptake, increased protein synthesis and decreased oxidation of
proteins. The more amino acids utilized by the cell and the
greater the protein synthesis, the greater the muscle growth.
Growth hormone enhances the utilization of fat by stimulating
triglyceride breakdown and oxidation in adipocytes (fat cells);
and hGH helps to maintain blood glucose within normal ranges.
Growth hormone is said to have anti- insulin activity, because
it suppresses the abilities of insulin to stimulate uptake of
glucose in peripheral tissues and enhance glucose synthesis in
the liver. For this reason, growth hormone stimulators should be
taken on an empty stomach and specifically should not be taken
with highly concentrated glucose drinks.
In humans the
amount of hGH secreted at age 20 is about 500 micrograms, at age
40 200 micrograms, and at age 80 only 25 micrograms. The fall in
IGF-1 is identical. hGH and IGF-1 production can be increased
significantly by the stimulation of growth hormone-releasing
hormone (GH-RH) by the pituitary gland, suppression of
somatostatin a feedback hormone that acts to block the release
of GH, and increased activation by the secondary messenger
3’,5’- cyclic ester of AMP (cAMP).
SecretaGAIN is formulated
with 2 scientifically derived multi-synchronized secretagogue
complexes:
#1 – SOMATROLINE™ COMPLEX- Increase the release of
GH-RH, Growth Hormone and IGF-1.
#2 – ADRENAVOL™ COMPLEX-
reduces the secretion of Somastatin the inhibitor of the release
of growth hormone, increases cAMP to influence GH-RH and hGH
synthesis.
#1 Somatroline™
SOMATROLINE™ is a proprietary
complex of specific secretagogue substances that stimulate the
release of GH-RH and hGH. 2-Amino-5-guanidinopentanoic-5 oxo
L-proline 2,6-Diaminohexanoic acid 2-Amino-4-(methylthio)
butanoic acid Simultaneous adminstration of these highly bio-
active micro protein increases secretion of hGH by the pituitary
gland. Clinical evaluations have shown plasma hGH levels
increasing by as much as 700% after 90 minutes. Basal hGH levels
increased from slightly over 12 ng/ml to over 90 ng/ml after 90
minutes, and after 8 hours plasma levels remained elevated at
over 45 ng/ml.
#2 Adrenavol™
ADRENAVOL™- is a proprietary
matrix of the potent substances that effectively suppress
somatostatin the feedback hormone that decreases free hGH
release, and increases cAMP levels to influence GH-RH and the
increased release of hGH. Alpha-GPC (alpha
glycerylphosphorylcholine) is a precursor to acetylcholine,
which is the most abundant neurotransmitter in the body and
typically very low in hard training athletes. Low acetylcholine
levels are directly related to high levels of somatostatin.
Thus, higher levels of acetylcholine and lower levels of
somatostatin result in higher levels of growth hormone. Coleus
Forskholii (forskolin) has been shown to increase the
“biological amplifying system” by increasing the synthesis of
the 3,’5’- cyclic ester of AMP (cAMP). cAMP is generated from
ATP by the action of adenyl cyclase that is coupled to hormone
receptors by G-proteins, a binding protein. GH-RH acts via cAMP
to promote the synthesis and release of hGH from pituitary
glands.
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