VitaNet ® LLC. Serving Customers Online Since 1995

The human body has many built-in regulating systems of checks 
and balances. And since Nitric Oxide is such a powerful 
compound, the Nitric Oxide pathway is one of the most complex. 
While arginine is the “raw material” used by the body to produce 
Nitric Oxide, there are many interactions along the Nitric Oxide 
pathway which influence Nitric Oxide production. 
  
The 
Nitric Oxide biochemical pathway can be influenced by these 
various co-factors: homocysteine, ADMA (asymmetric 
dimethylarginine), SOA (super oxide anion), SOD (super oxide 
dimutase) and perhaps the most critical of all NOS (nitric oxide 
synthase). The relationship between these co-factors has a 
direct influence on the amount of arginine that can be converted 
(synthesized) to Nitric Oxide. Remember, no matter how much 
arginine or arginine substrates (i.e. AAKG, arginine malate, 
arginine ethyl ester) you feed your body, the amount of Nitric 
Oxide you can produce is limited to these Nitric Oxide pathway 
co-factors. The best way to explain it is that while arginine is 
the fuel, these co-factors are the parts which make up the 
Nitric Oxide engine.