Glucosamine & Chondroitin - JOINT HEALTH - Glucosamine & Chondroitin - JOINT HEALTH
Everyone old enough to walk appreciates the value
of fl exibility and ease of movement. Unfortunately
many of us take such good things for granted. A famous
folksinger sang, “You don’t know what you’ve
got till it’s gone.” That’s certainly true for millions
of Americans who live with stiff and uncomfortable
joints.
Fortunately there are a number of nutrients available
that provide the vital components of healthy
joint structure and function and ease of mobility.
These nutrients are referred to as “chondroprotective
agents,” and include glucosamine and chondroitin,
which supply the raw material necessary to produce
new cartilage, and may even help rebuild worn cartilage.
Other chondroprotective nutrients and herbs,
like Cetyl Myristoleate, MSM, and Boswellin, work
synergistically with glucosamine and chondroitin
and further support normal joint function
To understand how chondroprotective agents work,
one must fi rst understand how joints work. The key
element in human joints is articular cartilage, the
shock-absorbing tissue that connects two bones
together and allows pain-free movement. Articular
cartilage is comprised of two different molecules,
collagen and proteoglycans, with the remainder
composed primarily of water (65-85%). Collagen,
a protein that binds tissue together, provides elasticity.
Proteoglycans, composed of sugars and protein,
absorb water, which provides lubrication and
resiliency, nature’s shock absorber for your joints.
Both compounds are produced by chondrocytes,
caretaker cells responsible for the formation and
maintenance of cartilage. A defi ciency in any one
of the above constituents will increase the likelihood
of wear and tear on articular cartilage, which
can eventually lead to compromised joint function.
Glucosamine and chondroitin are safe, natural and
effective nutrients that support healthy joint function
by supplying the materials needed to produce ...
Supports Healthy Joint
Structure and Function
Supports Mobility and
Ease of Movement
References:
1) Balch, James F. et. al. ; Prescription For
Nutritional Healing 3
rd
rd rdPrescription Edition
Edition
; Avery;
Penguin Putnam; 2000
2) Benedikt, H.; Glycosaminoglycans And
Derivatives For Treatment Of Arthritis;
Chiropractic Products, May 1997, pp.
92-95
3) Reginster, Jean Yves et. al.; Long-term
effects of glucosamine sulphate on
osteoarthritis progression: a randomised,
placebo-controlled clinical trial; The
Lancet, 2001, Vol. 357, No. 9252
4) Bassleer, C. et. al.; Stimulation of
proteoglycan production by glucosamine
sulfate in chondrocytes isolated from
human osteoarthritic articular cartilage
in vitro; Osteoarthritis and Cartilage,
1998, 6, 427-434
5) Drovanti, A. et. al.; Therapeutic
Activity of Oral Glucosamine Sulfate in
Osteoarthritis: A Placebo-Controlled,
Double-Blind Investigation; Clinical
Therapeutics, Vol. 3, No. 4, 1980, pp.
260-272
6) Morreale, P. et. al.; Comparison of the
Antiinfl ammatory Effi cacy of Chondroitin
Sulfate and Diclofenac Sodium in
Patients with Knee Osteoarthritis; Journal
of Rheumatology, 1996, 23:8, pp. 1385-
1391
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