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New cancer research centers on priming immune system. - New cancer research centers on priming immune system
A team from the National
Cancer Institute near
Washington D.C. may have
found an effective cancer treatment—
supercharging the
patient’s own immune system.
Promising results have come
from initial treatments on “sentry”
cells, the cells that make
the body aware of foreign
invaders and initiate massive
attacks on foreign invading cells
and toxins. Researchers were
able to “prime” these dendritic
cells for attack by adding proteins
from various cancers and
viruses to the dendritic cells.
Researchers found that the
modified dendritic cells
responded far better to invading
cells they were primed for.
In fact, mice given these
modified cells produced
more than six times the
number of T cells
(immune cells). The success
of this study could open up
more options in cancer and
HIV research. Beefing up the
immune system could be more
effective than current treatments.
Studies on humans are
scheduled to start soon.
Some researchers are worried
about using treatments
like this on HIV however,
because it and other immune
ailments (rheumatoid arthritis,
multiple sclerosis, etc.) can turn
the immune system against the
body itself. Giving more power
to the immune system could
make autoimmune symptoms
worse instead of better.
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