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New antibiotics expected for resistant pneumonia bugs - New antibiotics expected for resistant pneumonia bugs
Scientists recently
announced the expected
arrival of a new family of
bacteria-killers on the horizon
for pneumonia and
other diseases. These new
antibiotics should offer an
alternative to standard
antibiotics, many of which
have lost their punch
against increasingly resistant
germs.
The standard treatment
today for many bacterial
infections that cause respiratory
diseases are medicines
called macrolides.
These include well-known
antiobiotics like penicillin
and erythromycin.
However, certain bacteria
strains are growing resistant
to them, as well as to
the primary back-up medicines,
known as
quinolones.
The pharmaceutical
industry's response to this
problem is ketolides.
Ketolides are derived from
macrolides, but since they
have a different chemical
composition, they will kill
bacteria that are resistant
to macrolides.
Researchers recently presented
reports on two varieties
of ketolides at an infectious
diseases meeting sponsored
by the American
Society for Microbiology.
Aventis Pharmaceuticals
recently filed with the U.S.
Food and Drug
Administration to gain permission
to sell a new ketolide
antibiotic, Ketek, or
telithromycin. A similar drug
made by Abbott
Pharmaceuticals, code
named ABT-773, is also in
the early stages of human
testing.
Researchers presented
new Ketek studies involving
2,500 patients. These
reports intended to show
how the once-a-day Ketek
is equally effective as other
standard antibiotics in treating
many bacterial diseases,
including pneumonia,
bronchitis, sinus infections
and sore throats.
Scientist also say since
the Ketek treatment lasts
just five days, which is
shorter than most antibiotic
treatments, bacteria may
be less likely to grow resistant
to the new drug.
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