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Cancer fighter found in broccoli - Remember when your mother told you to eat
your broccoli? Research shows that mother
just might know best.
In a recently published paper, Dr. Paul Talalay
of Johns Hopkins University School of Medicine
indicates that studies in his lab show broccoli is
rich in sulforaphane, a chemical that works as a
powerful anti-cancer compound in laboratory
mice.
Other studies have shown that a diet rich in
cruciferous vegetables—which include broccoli,
Brussels sprouts, cabbage, cauliflower, and others—
can significantly reduce the risk of cancer of
the bowel, stomach and breast.
Until now, the exact reasons why these vegetables
had this effect we re not
very clear. Until now, that is.
According to Dr. Talalay, it
appears that at least one anticancer
ingredient in the vegetables
is sulforaphane, which
essentially causes cells to expel
cancer-causing toxins.
In addition, Dr. Talahay
said that this study was the first
to show that a high-potency compound isolated
from vegetables could accelerate the detoxification
process in cells.
The published report outlines how the
research team isolated sulforaphane from broccoli,
then fed it to a group of mice. When cells in
the mice we re examined after five days, the scientists
found that the chemical had triggered
enzymes known to neutralize carcinogens within
cells.
Be yond this study, Dr. Talalay indicates that
research will shift to the long-term effects of the
chemical. “Our prediction is that sulforaphane
will block tumor formation in animals and presumably
in man.”
In earlier studies, Dr. Talalay and others have
shown that certain proteins in cells, called phase
I enzymes, can take innocent chemicals and turn
them into cancer-causing agents.
Other proteins, called phase 2 enzymes, tend
to block formation of carcinogens. According to
the study, sulforaphane is a potent activator of
phase 2 enzymes.
The Hopkins researchers will conduct tests to
determine how much broccoli must be c ...
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