NOW: GLUTAMINE POWDER Pure 1000 Grams

GLUTAMINE POWDER Pure - 1000 Grams



by   NOW FOODS
*MSRP:
$69.99
Our Price:
$42.00
Buy: at $42.00
(3 for $ 41.99ea. = $ 125.97 ) 40% OFF MSRP
UPC: 733739002228
# N0222

NOW L-Glutamine Powder Pure 5000 mg (1,000 g / 200 Servings)

Product Overview & Quick Specs Snapshot

NOW L-Glutamine Powder Pure delivers 5,000 mg of 100% pure, crystalline free-form L-Glutamine (chemical formula: C5H10N2O3) per serving with zero fillers, zero sugars, and zero additives. L-Glutamine is the most abundant amino acid circulating in your bloodstream and stored inside your muscle tissue. Each scoop provides clean, fast-absorbing cellular fuel to protect your digestive intestinal lining, transport nitrogen safely across your organs, and fuel your body's active immune defenses [1, 2].

Quick Specs Snapshot

  • ✓ Active Form & Potency: 5,000 mg (5 grams) of pure, crystalline Free-Form L-Glutamine per single rounded teaspoon.
  • ✓ Primary Cellular Target: Direct fuel for intestinal lining cells (enterocytes), active white blood cells (lymphocytes and macrophages), and whole-body nitrogen balance [1, 2].
  • ✓ Supply & Value Math: About 200 full servings per heavy-duty 1,000 g (2.2 lb / 1 kg) container (over 6.5 months of daily support); backed by VitaNet®, LLC everyday discount pricing for bulk savings at just pennies per day.
  • ✓ Formulation Purity: 100% pure single-ingredient powder with zero other ingredients, non-GMO, vegan/vegetarian, and certified free of wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, and sesame.

Buyer's Guide & Pure Free-Form Comparison

Why Free-Form L-Glutamine Matters

In dietary protein like chicken or steak, amino acids are chained tightly together like links in a bicycle chain. Your stomach and intestines must spend time and digestive energy breaking those links apart before your body can absorb them. This NOW formula provides Free-Form L-Glutamine, meaning the molecule is completely unbonded and pre-separated. It glides effortlessly across your intestinal wall into your bloodstream without requiring digestive breakdown, delivering fast-acting cellular support with zero stomach heaviness [1]. Cheap mass-market and big box store brands often cut corners with low-grade, poorly purified powders that contain synthetic binders, chemical flow agents, or hidden contaminants. NOW delivers 100% pharmaceutical-grade purity verified by independent analytical testing [1, 2].

Is This Formula Right for You?

Ideal For Shoppers Who:

  • ✓ Want to soothe, protect, and rebuild their gut wall by feeding the cells that keep their digestive barrier strong and sealed [2, 3].
  • ✓ Need targeted immune system reinforcement during physical exercise, seasonal challenges, or demanding daily stress [1, 4].
  • ✓ Want the ultimate bulk value (1,000 grams / 200 full servings) of an unflavored, pure powder that easily mixes into water, juice, or shakes without swallowing pills.

Consider Another Option If:

  • ✘ You prefer pre-portioned, travel-ready capsules and dislike stirring unflavored powders into liquids.
  • ✘ You have a medical condition affecting your liver (such as cirrhosis or liver disease) or bipolar disorder, which requires direct physician supervision before supplementing with glutamine.
  • ✘ You prefer ready-to-drink, artificially sweetened fruit drinks rather than 100% pure, unflavored single-ingredient amino acids.
Risk-Free VitaNet® Guarantee: Every purchase is protected by our family-owned 100% money-back guarantee—even on opened containers, with return shipping covered by us—so you can test your digestive comfort and personal results with complete confidence.

How L-Glutamine Works: Gut Barrier, Nitrogen Transport & Immune Defense

Think of amino acids as the tiny building blocks that make up your body. While your body can manufacture some L-Glutamine (chemical formula: C5H10N2O3) on its own, it is officially classified as a conditionally essential amino acid [1]. That means whenever your body undergoes physical exercise, intense mental stress, or digestive discomfort, your cells burn through glutamine faster than your liver and muscles can produce it [1, 5].

1. Fueling the Intestinal Lining & Locking the "Cellular Zipper"

The inside of your gut is lined with a delicate, single-cell layer of tissue called enterocytes. Unlike most cells in your body that burn glucose sugar or fat for fuel, these intestinal cells prefer to burn L-Glutamine as their primary source of energy [1, 2]. Between these gut cells are specialized junctions that act like the teeth of a tight jacket zipper [2]. When your gut cells have plenty of glutamine, that cellular zipper stays firmly locked shut, preventing undigested food particles and waste toxins from escaping into your bloodstream while letting good nutrients pass through smoothly [2, 3].

2. The Body's Safe Nitrogen Delivery Truck

Every time your body repairs muscle fibers or synthesizes new enzymes, it requires organic nitrogen (N2). However, when tissues break down protein, they produce ammonia (NH3), which is toxic if left loose in the bloodstream. L-Glutamine acts like a safe biological delivery truck: it picks up extra nitrogen atoms, neutralizes them into harmless glutamine, and safely transports them between your muscles, liver, and kidneys [1, 5]. In the kidneys, it releases ammonium (NH4+) to help regulate your body's acid-base balance and maintain healthy blood pH levels [1, 2].

3. Fueling White Blood Cells for Strong Immune Defenses

Your immune system relies on armies of white blood cells (specifically lymphocytes, macrophages, and neutrophils) to seek out and neutralize foreign invaders. When an immune challenge arises, these cells must rapidly multiply and produce protective defense proteins [1, 4]. Clinical research proves that active immune cells consume L-Glutamine at rates equal to or even higher than glucose [1, 4]. Providing your body with supplemental free-form L-Glutamine ensures your immune cells have the fuel they need to respond swiftly and stay resilient [1, 4].

Suggested Usage, Daily Timing & Nutrient Synergy Protocol

Optimal Timing & Liquid Pairing

The suggested adult usage is 1 rounded teaspoon (approx. 5 grams) mixed into 8 to 10 ounces of water (H2O) or fruit juice, 1 to 2 times daily. Take preferably between meals or on an empty stomach. Free-form amino acids enter your bloodstream through specialized protein transporter gates located in the intestinal wall [1]. If you take glutamine at the same time as a high-protein whole-food meal (such as steak, chicken, or eggs), other dietary amino acids will compete for those same gates, slowing down absorption. Taking your powder in water or juice between meals ensures rapid, unimpeded cellular uptake [1].

Daily Routine & Split-Dosing Strategy

Dividing your intake across the day keeps cellular amino acid levels steady:

  • ✓ Morning Fasted Dose: Take 1 rounded teaspoon first thing in the morning with water. This provides immediate fuel directly to your intestinal lining after an overnight fast [2].
  • ✓ Post-Workout Recovery: Take 1 rounded teaspoon mixed into water or juice 30 minutes after exercise to help restore muscle nitrogen reserves and support tissue recovery [1, 5].
  • ✓ Bedtime Digestive Support: For intensive gut barrier care, take 1/2 to 1 teaspoon 30 to 45 minutes before sleep to support nighttime cellular renewal [2, 3].

Smart Synergies & Temperature Spacing Rules

  • ✓ Ideal Combinations: Pairs synergistically with daily probiotics (probiotics replenish beneficial microflora while glutamine nourishes the physical gut wall), Zinc Carnosine, Vitamin C, and Branched-Chain Amino Acids (BCAAs) for active muscle recovery.
  • ✘ Crucial Temperature Rule: Never mix L-Glutamine powder into boiling water, hot tea, or hot coffee. High heat can weaken the delicate amino acid bonds. Always use cool or room-temperature liquids.

Timeline of What to Expect

Week 1: Intestinal enterocytes rapidly absorb free-form glutamine. Many users report enhanced digestive comfort, smoother digestion, and reduced feelings of stomach irritation [2].

Weeks 3–4: Consistent daily nourishment reinforces intestinal tight junctions, supports healthy gut barrier integrity, and sustains white blood cell activity during physical exertion [1, 3].

Months 2–3+: Cumulative nitrogen balance supports muscle preservation, healthy tissue renewal, and lasting immune resilience [1, 5].

Physical Texture, Sensory Profile & Clean Ingredient Transparency

Powder Texture, Dissolvability & Appearance

NOW L-Glutamine Powder Pure is an ultra-pure, fine, crystalline white powder. Because it is 100% free-form amino acid with zero clump-inducing fillers or binders, a quick 10-second stir with a spoon in room-temperature water or juice suspends it evenly. It dissolves cleanly without leaving a thick sludge or chalky sediment at the bottom of your glass.

Natural Aroma & Taste Profile

This product is 100% odorless and unflavored. It has a very mild, neutral, and faintly sweet natural taste. When stirred into plain water, it is virtually undetectable. When blended into fruit juice, smoothies, or electrolyte drinks, it will not alter the flavor of your favorite beverage.

Other Ingredients Demystified

Other Ingredients: None. This formula is 100% pure active ingredient. There are zero synthetic flow agents, zero anti-caking powders, zero artificial colors, zero preservatives, and zero sweeteners.

Proper Bottle Storage & Freshness

Store your container in a cool, dry, dark pantry or cupboard after opening. Free-form amino acids are naturally sensitive to humidity and moisture. Keep the lid firmly screwed on between uses, and do not discard the enclosed food-grade freshness packet, which keeps the powder dry and free-flowing.

NOW Foods Laboratory Testing & Strict Contaminant Standards

Don't gamble your health on cheap big box store brands. Many discount supplements sold at mass retailers are manufactured by anonymous third parties that skip critical safety screening. Independent testing repeatedly reveals that off-the-shelf discount amino acids can be contaminated with heavy metals, diluted with cheap chemical fillers, or spiked with artificial nitrogen to fake protein levels. NOW Foods sets the gold standard for purity with private, in-house testing that surpasses standard industry requirements:

  • ✓ ISO/IEC 17025:2017 Accredited Laboratories: NOW operates world-class in-house analytical laboratories where chemists perform over 19,000 to 31,000 individual safety and potency tests every single month.
  • ✓ ICP-MS Heavy Metal Testing (Parts-Per-Billion Precision): Using Inductively Coupled Plasma Mass Spectrometry (ICP-MS), every batch of raw material is screened for toxic heavy metals—including lead, arsenic, cadmium, and mercury—to ensure levels easily clear strict California Proposition 65 and USP safety standards.
  • ✓ HPLC Molecular Potency & Identity Verification: High-Performance Liquid Chromatography (HPLC) verifies that each scoop delivers 100% pure L-enantiomer free-form glutamine, guaranteeing zero synthetic impurities or industrial chemical byproducts.
  • ✓ Microbiological Pathogen Bio-Screening: Every lot undergoes strict microbial culture analysis to confirm total absence of harmful pathogens, including Salmonella spp., Escherichia coli, and Staphylococcus aureus, alongside strict yeast and mold safety limits.
  • ✓ Audited cGMP Manufacturing: NOW facilities are independently audited and certified by UL Solutions and maintain an "A-rated" Good Manufacturing Practices (cGMP) registration through the Natural Products Association (NPA).

Supplement Facts & Retailer Verification

Supplement Facts

Serving Size: 1 Rounded Teaspoon (approx. 5 g)

Servings Per Container: about 200

Description Amount per Serving % Daily Value
Calories 20 **
L-Glutamine (Free-Form) 5 g (5,000 mg) †

† Daily Value not established.

** Percent Daily Values are based on a 2,000 calorie diet.

Other Ingredients: None.

Allergen Declaration: Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Safety Caution: For adults only. Consult physician if pregnant/nursing, taking medication, or have a medical condition (including liver disease or bipolar disorder). Keep out of reach of children. Do not eat freshness packet enclosed.

NOW® L-Glutamine Powder is a pure, free-form, non-essential amino acid and is the highest grade available. Natural color variation may occur in this product. This product is sold by weight not volume. Packaged and quality tested in the USA. Store in a cool, dry, dark place after opening.

Curator's Quality Note & Store Heritage

Manufactured by NOW Foods in an audited, cGMP-certified facility. Hand-selected, biochemically vetted, and shipped directly by VitaNet®, LLC. Founded in 1995 with a brick-and-mortar storefront in Hartville, Ohio, VitaNet® brings over 31 years of trusted supplement curation, customer care, and human biochemistry experience to your family's wellness journey.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Frequently Asked Questions & Scientific References

How should I measure a 5-gram serving of NOW L-Glutamine Powder Pure without a scale?

You can easily use a standard kitchen measuring teaspoon. One rounded teaspoon delivers approximately 5 grams (5,000 mg) of pure crystalline L-Glutamine. Simply scoop the powder with a normal teaspoon so it forms a gentle rounded mound over the rim.

Can I mix NOW L-Glutamine Powder into warm coffee, hot tea, or hot soup?

No, avoid mixing this powder into boiling hot liquids. High heat can weaken and break the delicate bonds of free-form amino acids, reducing their potency. For maximum benefits, always stir your powder into cool or room-temperature liquids such as water, apple juice, or smoothies.

Will taking NOW L-Glutamine Powder break an intermittent fast?

At a standard 5-gram serving containing 20 calories and zero sugar, carbohydrates, or fat, it will not trigger a meaningful blood sugar spike. When consumed in plain water during your fasting window, it is rapidly absorbed and directly fuels resting gut lining cells without disrupting metabolic fat burning [1, 2].

Why choose this 1,000 g (200-serving) bulk tub over smaller bottles or capsules?

This 1,000 g (2.2 lb) size delivers exceptional cost savings and convenience. It supplies a full 200 servings—more than 6.5 months of daily 5-gram doses. To get the same amount of active glutamine from standard 500 mg capsules, you would need to swallow 2,000 pills and buy roughly seventeen 120-count bottles. This pure powder offers the most economical and pure way to support your daily wellness.

What is VitaNet's return policy if this product does not agree with my stomach?

VitaNet®, LLC offers an unconditional 100% money-back guarantee on every product. If you are unsatisfied for any reason, VitaNet® will refund your purchase and cover the return shipping costs, even on opened containers.


Scientific References

  1. Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018;10(11):1564.
  2. Rao R, Samak G. Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. Journal of Epithelial Biology & Pharmacology. 2012;5(Suppl 1-M7):47-54.
  3. Wang B, Wu G, Zhou Z, et al. Glutamine and intestinal barrier function. Amino Acids. 2015;47(10):2143-2154.
  4. Calder PC, Yaqoob P. Glutamine and the immune system. Amino Acids. 1999;17(3):227-241.
  5. Gleeson M. Dosing and efficacy of glutamine supplementation in human exercise and sport training. The Journal of Nutrition. 2008;138(10):2045S-2049S.
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