UPC: 733739047298
# N4729

NOW Pygeum and Saw Palmetto Extract: Advanced Prostate & Urinary Tract Support

Maintaining lower urinary tract comfort and healthy prostate tissue becomes increasingly critical for men over the age of 40. NOW® Pygeum and Saw Palmetto Extract (120 Softgels) delivers a scientifically calibrated, standardized botanical formula designed to support healthy urinary flow, reduce nocturnal voiding frequency, and maintain normal prostate cellular integrity. Unlike generic saw palmetto pills that rely on unstandardized, raw powdered berries, this formula combines concentrated Pygeum africanum bark extract, standardized Serenoa repens berry extract, and cold-pressed Pumpkin Seed Oil. This lipid-based delivery matrix provides targeted phytosterols and essential fatty acids to promote optimal male hormonal balance and detrusor muscle tone.

The Dual-Action Mechanism: How Pygeum & Saw Palmetto Work Together

The combination of Pygeum and Saw Palmetto Extract targets prostate health from multiple physiological angles, offering synergistic support that single-herb formulas cannot match:
  • Inhibition of 5-Alpha Reductase (Saw Palmetto Berry Extract): Standardized to deliver a minimum of 85% bioactive fatty acids, Serenoa repens helps inhibit 5-alpha reductase - the primary intracellular enzyme responsible for converting circulating testosterone into dihydrotestosterone (DHT). Elevated DHT levels within prostate tissue drive benign glandular enlargement. By modulating 5-AR activity and blocking DHT from binding to androgen receptors, saw palmetto promotes healthy epithelial tissue architecture.
  • Modulation of Bladder Tone & Growth Factors (Pygeum Bark Extract): Sourced from the African evergreen tree (Pygeum africanum / Prunus africana) and standardized to 13% phytosterols (calculated as beta-sitosterol), pygeum acts directly on the bladder and detrusor muscle. Clinical literature demonstrates that pygeum's triterpenes and phytosterols help inhibit basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF), while reducing bladder irritability, easing urinary urgency, and supporting a steady urinary stream.
  • Essential Fatty Acid & Delta-7-Sterol Transport (Pumpkin Seed Oil Base): NOW formulated this supplement with a base of 1,500 mg cold-pressed Pumpkin Seed Oil (Cucurbita pepo) per serving. Pumpkin seed oil contributes bioavailable linoleic and oleic essential fatty acids alongside delta-7-phytosterols. Serving as a lipophilic carrier, it significantly enhances the intestinal bioavailability of the fat-soluble sterols in both pygeum and saw palmetto.

Targeted Benefits for Men's Lower Urinary Tract Health

Regular supplementation with standardized pygeum and saw palmetto with pumpkin seed oil provides multi-system functional support:
  • Promotes Peak Urinary Flow Rates (Qmax): Helps relieve pressure on the urethral channel to support a more forceful, uninterrupted urinary stream.
  • Reduces Frequent Nighttime Urination (Nocturia): Assists the bladder in emptying more fully, cutting down on sleep interruptions caused by the constant urge to void.
  • Soothes Localized Inflammation: Phytosterols and pentacyclic triterpenes help downregulate eicosanoid and 5-lipoxygenase (5-LOX) inflammatory pathways within prostatic tissues.
  • Supports Long-Term Hormonal Balance: Helps buffer localized androgen conversions in aging men without suppressing systemic vitality.

Complete Supplement Facts & Ingredient Profile

Every production batch of NOW Pygeum & Saw Palmetto Extract undergoes comprehensive analytical testing, including high-performance liquid chromatography (HPLC), to verify potency, purity, and exact botanical standardization.
Supplement Facts Serving Size: 2 Softgels | Servings Per Container: 60
Component Amount Per Serving % Daily Value
Calories 15 *
Total Fat 1.5 g 2%**
  Polyunsaturated Fat 0.75 g †
  Monounsaturated Fat 0.75 g †
Saw Palmetto Extract (Berry) (Serenoa repens) [Standardized to min. 85% Fatty Acids] 160 mg †
Pygeum Extract (Bark) (Pygeum africanum) [Standardized to min. 13% Phytosterols] 50 mg †
Pumpkin Seed Oil (Cucurbita pepo) (Cold-Pressed) 1.5 g (1,500 mg) †
** Percent Daily Values are based on a 2,000 calorie diet. † Daily Value not established. * Daily reference values represent standard caloric intake.
Other Ingredients: Softgel Capsule [bovine gelatin (BSE-free), glycerin, water, carob]. Allergen Free From: Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, or sesame ingredients. Produced in a certified GMP (Good Manufacturing Practice) facility that processes other ingredients containing these allergens. Quality Assured: Non-GMO formulation. Bottle made from 100% Post-Consumer Recycled (PCR) resin. Packaged and quality tested in the USA with globally sourced raw materials.

Suggested Usage & How to Optimize Results

Directions: Take 2 softgels twice daily with food, or as directed by your qualified healthcare practitioner. Clinical Usage Note: Taking 2 softgels twice per day provides 320 mg of standardized Saw Palmetto Extract (85% fatty acids) and 100 mg of standardized Pygeum Extract (13% sterols) per day. This matches the exact daily dosage studied in European clinical trials for optimal prostate and lower urinary tract efficacy. Storage: Store in a cool, dry, dark environment after opening. Natural color variation of the botanical lipid blend is normal and does not impact potency.

Safety Precautions & Drug Interactions

This product is intended strictly for adult use. Pygeum and Saw Palmetto alter androgenic pathways and may exhibit mild antiplatelet effects. Always consult your primary physician or urologist before starting this supplement if you:
  • Are currently taking prescription medications for Benign Prostatic Hyperplasia (such as Finasteride, Dutasteride, or alpha-blockers like Tamsulosin).
  • Are taking blood thinners (anticoagulants/antiplatelets) or hormone therapies.
  • Have an existing medical diagnosis or are planning scheduled surgery.
Keep out of reach of children. Do not use if safety seal is damaged or missing.

Frequently Asked Questions About Pygeum & Saw Palmetto Extract

How does the combination of Pygeum and Saw Palmetto Extract support prostate health?

Saw Palmetto and Pygeum work synergistically via complementary pathways. Saw Palmetto primarily inhibits the 5-alpha reductase enzyme to decrease dihydrotestosterone (DHT) production in prostate tissue, while Pygeum provides concentrated phytosterols and triterpenes that support detrusor bladder muscle elasticity, ease urethral resistance, and decrease nighttime urinary urgency.

Why is Pumpkin Seed Oil included in this softgel formula?

Pumpkin Seed Oil is rich in essential fatty acids (linoleic and oleic) and delta-7-sterols, which provide their own documented benefits for bladder tone. Additionally, because the active sterols in saw palmetto and pygeum bark are lipophilic (fat-soluble), the cold-pressed pumpkin seed oil base acts as a natural delivery system that dramatically improves intestinal absorption and bioavailability.

What does botanical standardization mean, and why is it important?

Standardization guarantees that every batch delivers a clinically verified concentration of active chemical constituents. NOW Pygeum & Saw Palmetto Extract guarantees a minimum of 85% fatty acids in the saw palmetto berry extract and 13% phytosterols in the pygeum bark extract. Non-standardized raw plant powders can vary dramatically in potency and often fail to produce consistent clinical results.

How long does it take for Pygeum and Saw Palmetto Extract softgels to work?

Because botanical extracts work gradually by balancing localized tissue hormones and cellular pathways, most clinical studies show measurable improvements in urinary stream and reduced nighttime trips to the bathroom within 4 to 8 weeks of consistent, twice-daily use.

Can I take Pygeum and Saw Palmetto if I am already taking prescription prostate medication?

If you are currently taking prescription 5-alpha-reductase inhibitors (such as finasteride or dutasteride) or alpha-blockers (such as tamsulosin/Flomax), you must consult your urologist or physician before starting this supplement. Combining botanical 5-AR inhibitors with prescription medications could produce additive effects.

Is this product suitable for women or young adults?

NOW Pygeum & Saw Palmetto is formulated specifically for adult men seeking prostate and urinary support. Due to its anti-androgenic effects, it is not recommended for women who are pregnant, nursing, or planning to become pregnant, and it should not be used by children.
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