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$65.98- Our Price:
- $47.52
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- Features:
- Anti-aging
- Enhances metabolism
- Hormonal balance
- Increase lean muscle
- UPC: 021078024651
- # SN2465
Source Naturals 7-KETO DHEA 100mg (60 Tablets)
Non-Stimulant Thermogenic Metabolite for Metabolic Rate & Healthy Weight Management
Source Naturals 7-Keto DHEA 100mg delivers a clinically researched, non-hormonal derivative of dehydroepiandrosterone (DHEA) formulated to support cellular energy production, thermogenesis, and resting metabolic rate. Unlike standard DHEA, 7-oxo-DHEA acetate does not convert into active androgens or estrogens, making it a preferred choice for individuals seeking metabolic and body-composition support without androgenic or estrogenic side effects.What Is 7-Keto DHEA? The Science of 7-Oxo-DHEA
Dehydroepiandrosterone (DHEA) is the most abundant circulating steroid hormone precursor produced by the human adrenal glands. Circulating concentrations peak in early adulthood (around ages 20 to 25) and steadily decline by up to 80% over the lifespan. When the body metabolizes DHEA, it produces several downstream compounds, one of the most biologically active being 7-oxo-DHEA (commonly known as 7-Keto®).The Key Difference: Non-Hormonal Pathway
While standard DHEA readily metabolizes into downstream sex steroids—including testosterone, dihydrotestosterone (DHT), and estrone/estradiol—7-Keto DHEA cannot be converted back into active sex hormones. The oxygenation (ketone group) at the 7-carbon position permanently blocks conversion through the steroidogenesis pathway. This ensures that users experience the cellular and metabolic benefits of DHEA metabolites without triggering hormone-dependent side effects such as acne, hair loss, voice deepening, or shifts in prostate/breast tissue markers.How It Works: Thermogenesis and Enzyme Induction
The primary physiological action of 7-oxo-DHEA acetate is the enzymatic stimulation of thermogenesis—the biochemical process of cellular heat generation in brown adipose tissue and hepatic mitochondria. Research indicates that 7-Keto DHEA upregulates three key metabolic enzymes involved in cellular energy expenditure and fatty acid oxidation:- Hepatic Malic Enzyme: Converts malate to pyruvate while generating NADPH, accelerating substrate oxidation.
- Fatty Acyl-CoA Oxidase: Serves as the initial, rate-limiting enzyme in peroxisomal beta-oxidation of long-chain fatty acids.
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GPDH): Facilitates the glycerol phosphate shuttle, driving electrons directly into the mitochondrial respiratory chain to enhance caloric expenditure as heat rather than storing it as adipose tissue.
Comparison: 7-Keto DHEA vs. Standard DHEA
| Key Attribute | Source Naturals 7-Keto DHEA 100mg | Standard DHEA |
| Primary Active Compound | 7-oxo-DHEA Acetate | Dehydroepiandrosterone |
| Hormonal Conversion | None (Cannot convert to testosterone or estrogen) | Converts directly to androgens and estrogens |
| Primary Target | Basal metabolic rate, thermogenesis, lean body mass | Endocrine restoration, androgen/estrogen replenishment |
| Stimulant Activity | Zero (Non-stimulant, jitter-free) | Non-stimulant |
| Endocrine Side Effects | Low risk (does not stimulate hormone-sensitive tissues) | Potential for acne, hair changes, mood fluctuation |
| Ideal Use Case | Metabolic support during caloric restriction, fat loss support | Age-related hormone replacement therapy (under clinical guidance) |
Key Health Benefits
1. Enhanced Resting Metabolic Rate & Fat Oxidation
Caloric restriction often causes a compensatory drop in basal metabolic rate (BMR). Clinical trials indicate that 200 mg daily of 7-Keto (taken as 100 mg twice daily) helps preserve resting metabolic expenditure during weight-management programs, facilitating greater fat loss when paired with balanced nutrition and physical exercise.2. Stimulant-Free Thermogenic Energy
Unlike thermogenic formulas reliant on high-dose caffeine, synephrine, or yohimbine, Source Naturals 7-Keto DHEA 100mg supports cellular caloric burning without:- Elevation of resting heart rate or blood pressure
- Nervous jitters, restlessness, or "adrenal crashes"
- Disruption of natural circadian rhythms or sleep architecture
3. Lean Muscle Mass Support
During weight management phases, the body often catabolizes muscle tissue alongside adipose stores. By stimulating fatty acid oxidation, 7-oxo-DHEA helps spare lean muscle mass, supporting functional strength and physical tone.4. Immune & Cognitive Vitality
Preliminary research highlights that 7-Keto DHEA enhances cellular immunity by supporting T-cell mediated response and offers neuroprotective support against oxidative stress in aging brain tissue.Complete Supplement Facts & Ingredient Profile
| Supplement Facts | Amount Per Serving | % Daily Value |
| Serving Size: 1 Tablet | ||
| Servings Per Container: 60 | ||
| 7-oxo-DHEA Acetate | 100 mg | † |
Other Ingredients:
- Microcrystalline cellulose
- Stearic acid
- Magnesium stearate
Dietary & Allergen Profile:
- Vegetarian Formula: Contains no animal-derived gelatin or animal byproducts.
- Allergen Free: Contains no yeast, dairy, egg, gluten, corn, soy, or wheat.
- Pure Formula: Free from sugar, starch, salt, synthetic preservatives, artificial colors, artificial flavors, or fragrances.
- Product Identifiers: SKU: SN2465 | UPC: 021078024651
Suggested Use & Dosage Protocol
- Recommended Daily Intake: Take 1 tablet twice daily, preferably with morning and midday meals.
- With Food: Consuming with a meal containing moderate dietary fat optimizes gastrointestinal tolerance and systemic absorption.
- Consistency: For metabolic optimization and body-composition benefits, daily use alongside a structured exercise regimen and caloric-conscious nutrition is recommended for at least 8 to 12 weeks.
Safety, Contraindications & Quality Standards
- Physician Consultation: If you are currently taking prescription thyroid medications, hormone replacement therapy (HRT), or are undergoing treatment for any medical condition, consult your healthcare practitioner prior to use.
- Pregnancy & Lactation: Do not use if you are pregnant, planning to become pregnant, or breastfeeding.
- Age Limit: Not formulated for individuals under 18 years of age.
- Tamper Evident: Do not consume if the inner safety seal or outer shrink band is torn, damaged, or missing. Keep securely sealed in a cool, dry place out of reach of children.
Frequently Asked Questions (FAQ)
Does Source Naturals 7-Keto DHEA affect estrogen or testosterone levels?
No. Unlike standard DHEA supplements, 7-oxo-DHEA acetate is biochemically altered at the 7th carbon position. This modification prevents it from metabolizing into active sex hormones, including estradiol, estrone, testosterone, and DHT. It provides metabolic support without disrupting endocrine balance.How does 7-Keto DHEA differ from caffeine and other fat burners?
Standard fat burners rely on central nervous system (CNS) stimulants like caffeine anhydrous, green tea extract, or guarana. These compounds elevate heart rate and induce adrenaline release. In contrast, 7-Keto DHEA functions entirely through non-stimulant cellular pathways by upregulating thermogenic liver enzymes (such as fatty acyl-CoA oxidase and malic enzyme), making it completely jitter-free.What is the best time of day to take 7-Keto DHEA 100mg?
The most effective schedule is taking one 100 mg tablet with breakfast and a second 100 mg tablet with lunch. Because it supports cellular energy production, evening doses are generally avoided to prevent interference with natural sleep cycles.Can 7-Keto DHEA be taken alongside thyroid medication?
7-Keto DHEA influences the activity of enzymes associated with metabolic regulation, including those interacting with thyroid hormone pathways (such as T3 conversion). If you take levothyroxine, liothyronine, or natural desiccated thyroid, speak with your endocrinologist or primary care physician before introducing this supplement.Will taking 7-Keto DHEA cause a positive result on athletic drug screenings?
Certain athletic anti-doping bodies (such as WADA) monitor DHEA and its related metabolites under anabolic and metabolic modulator categories. While 7-Keto does not exert anabolic-androgenic steroid activity, competitive athletes subject to strict anti-doping regulations should review their sanctioning organization's banned substance list before use.How long does it take to see results with 7-Keto DHEA?
In clinical trials, statistically significant improvements in metabolic rate and body composition were measured over an 8- to 12-week timeframe when participants coupled 200 mg daily of 7-Keto with regular exercise and a controlled caloric diet.Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider prior to starting any new dietary supplement program.
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