Curcumin can Help with Inflammation Pain!
|Curcumin and Pain||Darrell Miller||12/02/10|
December 02, 2010 12:33 PM
Author: Darrell Miller (firstname.lastname@example.org)
Subject: Curcumin and Pain
Make no mistake about it: curcumin has long been identified as the compound responsible for the anti-inflammatory benefits of the ginger plant turmeric. The herb turmeric has been around for ages, cultivated for its wide array of culinary and medicinal uses that transcend regional and cultural boundaries. Apart from the popular use of its powdery form in bread, cakes, ale, and beer as a flavoring, the plant contains up to 5 per cent curcumin, which is one type of polyphenols now being looked into for its antioxidant properties.
Prostaglandin and Inflammation Pain
Autocrines and paracrines are contained in almost all tissues and organs to effectively participate in bodily defenses every time the systems call for them, for example in treating wounds. Prostaglandins are either autrocrines or paracrines that take on the job of signaling the tissues and systems implicated in defensive reactions when the body detects unwanted and harmful stimuli. Cells release autocrines to have an effect on the same cells and paracrines to aid nearby cells, making these compounds function as effective chemical messengers in immediate vicinities anywhere in the body as they are short-lived.
Prostaglandin is known as the chemical messenger causing pain and igniting fever among others. Defensive mechanisms start when cells release mediators, including prostaglandin, which brings about the known signs of inflammation. Prostaglandins relax smooth muscle cells within the walls of blood vessels in the area of inflammation and promote the flow of needed fluids like blood and plasma proteins into the spot, leading to the subsequent redness and swelling. They continue to mediate the healing process by permitting the entrance of neutrophil granulocytes, the front-line soldiers against harmful stimuli, and consequently put an end to invading pathogens. The same group of chemicals also increases pain at the same time, for example the joint pains associated with inflammation called arthritis.
Curcumin and Anti-inflammation
Painkillers, classified as analgesic drugs, work in a number of ways that in the end relieve the continual sensitization of certain body parts to pain. One group called non-steroidal anti-inflammatory drugs such as aspirin and ibuprofen targets the enzyme that catalyzes the synthesis of prostaglandins aim to reduce levels of prostaglandins.
Curcumin works on the same principle. Take for example, joint pains caused by arthritis. Be reminded that individuals who complain about joint pains are suffering from varied forms of medical conditions, which one way or another contribute to the pain in addition to having excessive levels of prostaglandins in the joints involved. Damage to the joint brought about by wear and tear or forced movement involving joints spurs the body to take defensive measures that include inflammatory effects, thus the pain. The intake of curcumin and its derivatives act on the cells in its production of prostaglandins, resulting in both the easing of pain and the lessening of inflammation.