EGCG in green tea
|EGCG in green tea||Darrell Miller||05/10/14|
May 10, 2014 07:38 AM
Author: Darrell Miller (firstname.lastname@example.org)
Subject: EGCG in green tea
Green tea benefits
Green tea is made from the leaves of Camellia Sinensis, which is recognized for its health benefits. The nonfermented product is obtained by leaf desiccation that contains potent, polyphenolic antioxidants, with a flavanolic structure referred to as green- tea catechins, including epigallocat-echin-gallate (EGCG). Studies have shown that drinking EGCG prevents carcinogenesis in rodent organs. Studies have shown it had a significant chemoprotective effect against DMBA-induced mammary tumorigenesis in rats. Human breast cancer cell proliferation inhibition by green tea appeared mediated in part by (CKI). Mutagenesis was inhibited at concentration levels equivalent to human daily consumption.
Using human umbilical vein endothelial cells, it was demonstrated that green tea extracts reduced expression of vascular endothelial growth factor (VEGF) receptors forms-like tyrosine kinase and fetal liver kinase. Kinase insert domain containing receptor. Because of the antiangiogenic property of its extracts, they have therapeutic potential in preventing the development of new microvascular networks (angiogenesis) needed for tumor growth. It was also found that green- tea polyphenols inhibited angiogenesis by reducing vascularization of chicken chorioallantoic membrane (CAM) by an angiogenin-like protein isolated from goat serum.
EGCG effectively inhibited bladder-tumor implantation growth in rats, pointing to its potential as an intravesical chemotherapeutic agent. Inhibition of platelet function is a factor in reducing the risk of coronary artery disease. EGCG was reported to inhibit platelet aggregation, by possibly involving inhibition of cytoplasmic calcium increase. EGCG was proven to be the most effective in reducing thrombin-induced aggregation of washed human platelets. The ability of green- tea catechins to inhibit adenovirus infection and adenain, the human adenovirus 2 endopeptidase, was reported. EGCG proved the most potent inhibitor of four green-tea catechins tested. The viral protease adenain appeared to be the target of EGCG, so it is possible that all adenoviruses are sensitive to its action.
The Chinese have known about medicinal qualities of green tea since ancient times, treating everything from headaches to depression.
The three "Es"
- enjoyment (soothing)
- energy (caffeine)
- essential health benefits (antioxidants)
Provides support for a healthy weight loss program, gives the energy needed to maintain an active lifestyle, health, and longevity. The appetite suppressor, Vanadium, reduces calorie intake. Thermogenesis, or fat metabolism, is increased, because of the EGCG/caffeine combination, therefore burning fat.
EGCG fights free radicals. Fatty acids and lipids in the brain are susceptible to the effects of free radical perodixation. Much of the aging of the brain is attributed to perodixation. The EGCG helps to keep us young, alert, and able. Researchers have found that EGCG has inhibited tumor growth in both skin and gastrointestinal tracts. EGCG may fermented be able to obliterate cancer cells, without harming neighboring tissues.