How does CBD help with Seizures

Darrell Miller

12/19/16

Date: December 19, 2016 10:28 PM
Author: Darrell Miller
Subject: How does CBD help with Seizures

Seizures are the sudden changes in the brain's electrical activity. It usually affects how a person acts for a short period of time or appear. The symptoms of seizure include a loss of control and violent shaking. There can be several causes for the seizures. Anything that affects the brain's normal activity can lead to seizures. Several causes of seizures include injury to the head, fever, disease or even certain uses of medications. A person suffering from regular seizures due to brain disorder is called to be having epilepsy. Seizures can take different forms that affect many people in different ways, as some people call it electrical storms in the brain.


CBD, also known as Cannabidiol is one of the cannabinoids found in Cannabis that has potential medical benefits. CBD is non-psychoactive that does not psychoactive effects in the body, instead has shown positive outcomes in curing seizures. The reason behind why CBD is non-psychoactive is due to lack of affinity of CBD for CB1 receptors. CB1 receptors are present in a major concentration in the brain which is responsible for the psychoactive effect of THC. Most of the people suffering from seizures have reported the positive outcome, while they were on treatment with CBD. In recent years, CBD has been claimed to be most beneficial medication for the treatment of epilepsy. People who were under the treatment of anti-seizure medication called Clobazam has also responded positively in favor of Epidiolex, that contains 99% oil-based extract of CBD.

CBD has several therapeutic effects. Unlike THC, CBD has a less binding affinity to the CB1 and CB2, those are Cannabinoid receptors. Instead, CBD stimulates endogenous cannabinoid signal by suppressing enzyme fatty acid amide hydroxylase (FAAH). CBD helps in enhancing endocannabinoid by suppressing FAAH. CBD also opposes the action of THC at CB1 receptor, thus help to mute the effects of THC. CBD also stimulates 2-AG, that activates the CB1 and CB2 receptors, where CB2 receptors are predominant in the immune system and peripheral nervous system. It is found that CBD binds directly with 'G-protein' coupled receptors and other ion channels to grant therapeutic effect. CBD is also known as the TRPV-1 stimulant that helps, CBD-rich Cannabis in the effective treatment of the neuropathic pain.