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CuraMed Coupon
Date:
November 18, 2023 10:26 AM
The Magic of Turmeric Unleashed: Terry Naturally CuraMed (Save with our Coupon)Terry Naturally CuraMed is your perfect partner for a healthy, vibrant life, harnessing the potent power of the ancient spice, turmeric. This product packs the incredible benefits of curcumin, the most potent component of turmeric. Hailed for centuries for its health benefits, curcumin is a powerful antioxidant and inflammation-buster, helping your body perform at its best. Curcumin has a rich history dating back thousands of years. This golden spice was widely used in Ayurvedic medicine and applauded for its anti-inflammatory properties. Modern science has corroborated these ancient practices, supporting the benefits of curcumin for brain, heart, and liver health, as well as immune system support. Curcumin works in the body by modulating numerous molecular targets and signaling pathways. It is known to inhibit the production of inflammation-causing enzymes, thus reducing inflammation in the body. This makes Terry Naturally CuraMed an ideal choice for those seeking an effective, natural anti-inflammatory supplement with no side effects. Our customers are health-conscious individuals seeking a reliable, natural supplement to reduce inflammation and optimize their overall health. Terry Naturally CuraMed is perfect for these needs. Its patented formula ensures enhanced absorption and sustained release, ensuring the curcumin stays in the blood for as long as 8 hours. CuraMed Features:
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Date:
September 06, 2023 04:55 PM
Add a dose of robust health to your daily routine with Terry Naturally CuraMed! This premium dietary supplement, enhanced with BCM-95® Curcumin, stands out in its ability to deliver potent bioavailable curcumin, enhancing your body's natural defense against inflammation and pain.
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Date:
February 13, 2021 10:10 AM
PlusCBD has a new 0.00% THC CBD Supplement line. Tested down to 50ppm to contain no THC. IF you are afraid of CBD products showing up in drug testing, consider this new CBD only product that contains no THC.
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Date:
November 15, 2015 08:38 PM
Today, one of the most serious conditions that people face is hypertension, or as it is commonly known, high blood pressure. This is grave condition, that if not checked, can result to fatalities. This condition is mostly found in people who are over 40 years. However, it is not unlikely to find a teenager with hypertension. This is a worrying trend which means that something must be done to prevent it. Luckily, there is a simple solution that people can apply to control this condition. To start with, it is important to understand what causes the condition so that one may know how to combat it. High blood pressure is primarily caused by the constriction of the arteries which makes it hard to pump blood. The arteries are thinner than the veins and this means that the blood in them is at a higher pressure than in the veins. Due to the narrowness, they are able to pump blood faster and for longer distances. When a person feeds on unhealthy food that is rich in cholesterol and other harmful substances, this causes a deposition of the harmful substances on the endothelium (the interior surface of the arteries). When this happens, the arteries become more constricted thus increasing the pressure of blood that flows in them (hence the term high blood pressure). When the pressure increases, there is insufficient supply of blood to vital organs of the body like the brain. When the brain is not supplied with enough nutrients in the blood, this could lead to brain damage or stroke that may cause paralysis. Again, to ensure enough blood gets to the brain, the heart is forced to pump blood faster. This overworks the heart which may lead to heart attacks. Heart attacks are usually fatal. There is therefore a need to unblock the heart vessels to ensure that blood flows easily. Nitric oxide is one of the best known remedy to people suffering from high blood pressure. It helps lower the blood pressure by unblocking the arteries. It has numerous benefits to the body especially in lowering the blood pressure. Arteries are able to release nitric oxide but as one advances in age, their effectiveness diminishes with time. Beet roots are a great source of nitric oxide. Eating lots of them will help supply your body with the nitric oxide it needs to unblock the arteries and thus lower the blood pressure. The whole beet root plant including the leave and the roots provides are rich source of nitric oxide. For those who don’t like eating it raw or cooked, they can juice it and still get the nutrients. Apart from lowering hypertension, beet roots are also known to fight against cancer. These are enough reason why anyone should increase their intake of beet roots whether or not they are suffering from high blood pressure. Beet roots juice is available in stores which could act as a powerful supplement to combat hypertension. References //www.nutritionexpress.com/showarticle.aspx?articleid=286 //www.medicalnewstoday.com/articles/288229.php
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Date:
July 22, 2015 01:25 AM
Cordyceps is simply a fungus. Not typically kitchen friendly, but if health is your number one target, then it will make the best supplement in your system. Before we go deeper into its benefits let us first have a clear understanding of what this unpopular yet effective medicinal fungi is. What is Cordyceps? It is simply an ascomycete fungi genus with approximately four hundred species that are mainly parasitic. They weren't considered beneficial to health until a recent discovery of Cordyceps Sinensis popularly known as a caterpillar fungi (It attaches itself on the caterpillar). Despite limited research on its health benefits, Cordyceps seems to be the best remedy for most of the health complications related to poor diet, lack of exercise and more. Let us take a look at some of its benefits. 1. A remedy for kidney disease - Cordyceps prevent rat's renal fibrosis. This condition (renal fibrosis) is evident in later stages of the organ. However, there is still need for more research on this fact. 2. Slows down Tumor Growth - There is some proof that Cordyceps trigger the immune system to combat cancer. Ability to improve the immune system was due to a result of research where there were some indications that Cordyceps slowed down tumor growth in many animals. 3. Increase libido - Lots of studies shows that Cordyceps raise the level of testosterone in rats. There are some claims that it also enhances sexual performance that is also yet to be proven. Apart from slowing down tumor growth, kidney disease and increasing sexual performance that are yet to be confirmed, Cordyceps have other numerous health benefits according to researchers that are, * Increase body oxygen uptake - Needed for maximum athletic performance. * Reduce the aging effects - Slows down aging that has remained a bother for centuries. * Strengthen muscles - For weight lifters and athletes looking to gain strong muscles with a little workout. * Improves lung function - Improves breathing needed for athletic performance * Good for the liver - Slows down liver complications that are known to lead to a liver transplant. There are also some claims that Cordyceps may replace the steroids when it comes to improving athletic performance and muscle building. Among these claims is that Cordyceps can enhance stamina needed mostly by sportsmen and women. Other researchers claim that it can tone muscles, increase energy and even reduce fatigue after a long time of work. In summary, the caterpillar fungi (Cordyceps) has a lot in store when it comes to solving health complications. However, these claims are yet to be confirmed. If the facts are as real as the researchers claim them to be, then Cordyceps will be at the top of the top list of best natural supplements ever discovered. https://en.wikipedia.org/wiki/Cordyceps //www.gnet.org/cordyceps-benefits/ //www.healthline.com/health/cordyceps-exercise-performance#1 //www.drugs.com/npp/cordyceps.html Read More
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Date:
July 20, 2015 01:32 AM
Mushrooms are plants that belong to the fungi kingdom. These plants are not classified as vegetables, they provide essential and vital nutrients to our bodies. It is a common knowledge that the key to building strong immune systems and getting enough minerals and vitamins in the diet is by supplementing a variety of colorful fruits and vegetables, the more the color the better. This knowledge has however left mushrooms, which offer a wide variety of nutrients and antioxidants to our bodies, in the dark. In many cases, foods are only considered to be nutritious if they are colored. However, this is not true for mushrooms. Let's take a look at three most common mushrooms that positively impact the overall immune system and how they make it happen. Maitake mushrooms are common in Asian countries. This mushroom subspecies has shown effectiveness in the treatment of cancer. They can also be used to treat some side effects that are commonly associated with various chemical treatments such as chemotherapy for cancer. It is also used in the other conditions such as chronic fatigue syndrome, HIV/AIDS, Hepatitis, high cholesterol, hay fever, weight loss, diabetes, hypertension and infertility due to poly cystic ovary syndrome. How it works This species of mushroom contains chemicals that might stimulate the immune system and help fight tumors. There is also evidence that it can also be used as an effective regimen in efforts to lower blood pressure, lower blood sugar levels, improve cholesterol levels. Studies have also shown that it is effective in weight loss management. Reishi mushrooms are a type of fungi that some people describe as "woody" and "tough". The fruiting body of this plant and the filaments connecting a group of mushrooms has been used greatly as medicine. The plant is also used to boost the immune system, lung conditions including bronchitis and asthma, viral infections such as swine flu, influenza and avian flu, heart disease. It is also effective in maintaining other contributing conditions such hypertension, high cholesterol, liver disease and cancer. Other conditions where Reishi mushrooms are used are insomnia, stomach ulcers, chronic fatigue, herpes pain and poisoning. In combination with other forms of herbs, they are also used in the treatment of prostate cancer. Reishi mushrooms contain a wide variety of antioxidants and chemicals that have potential benefits and effects on the immune system and activity against tumors. An extract made from this mushroom is used as medicine. Although it is used widely as medicine, it is also consumed as food. Shiitake mushrooms are used to lower blood cholesterol levels, boost t-cells and as an anti-aging agent. This type of mushroom contains chemicals that help in lowering cholesterol levels. It contains chemicals that keep cancerous tumors from getting bigger. References: 1. //www.medicalnewstoday.com/articles/278858.php 3. //www.healthline.com/health/reishi-mushroom-key-to-immortality#2
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Date:
December 01, 2007 09:05 AM
Periwinkles form the plant genus Vinca, of which the lesser periwinkle and the greater periwinkle are the two members. They are also a form of dogbane, known for its alkaloid properties. Periwinkles are of interest to the medical profession due to their biosynthesis of a number of alkaloids that are used to protect themselves from bacteria and are also toxic to the herbivores that would otherwise eat them.
Many other plants produce alkaloids, perhaps the best known being poppy, that produces the alkaloid opium that is the precursor to heroin. The alkaloids of the periwinkle, however, have a much more beneficial use for mankind in their action on certain types of cancer such as Hodgkin’s disease, and also on the flow of blood to the brain.
The components of the periwinkle include vinblastine, which is used in the treatment of Hodgkin’s lymphoma, and it is the only plant known to produce the alkaloid, although only in very small quantities after synthetic seeding. This involves introducing modified tryptamines to the plant so that they produce the desired alkaloid, although only in quantities of 0.002% of the weight of the plant. Although small, this is still less expensive that synthesizing the alkaloid in a chemical plant rather than a biological one!
Chemists are now seeking more readily synthesizable alternative forms of the alkaloid that have the same effect, again using the periwinkle as a botanical chemical factory to provide them with a lead as to possible synthetic routes. However, it is for the application of another alkaloid of this amazing little plant that we are more concerned with here.
In addition to vinblastine, the periwinkle produces the alkaloid vincamine, a type of tryptamine that can be extracted from the leaves of the lesser periwinkle, the Vinca minor. This periwinkle has been used through the ages as an invigorating tonic and as an astringent to treat bleeding gums and sores in the mouth. Vincamine promotes the aerobic glycolysis that is essential to cerebral health.
Normal glycolysis, or the conversion of glucose to energy in the mitochondria of the cells of the body, occurs best in the absence of oxygen (anaerobic glycolysis). However, the brain produces up to and over 90% more energy through aerobic glycolysis in the presence of oxygen than through anaerobic. Hence one of the needs for such a rich supply of oxygenated blood being needed by the brain. As people grow older, or their brain tissue becomes damaged, then the supply of blood can be reduced and more and more anaerobic glycolysis is switched on. This results in an increasing loss of brain energy and hence brain function. Vincamine can reverse this effect, or at least maintain the status quo, and so enable people to maintain their brain function for longer.
It is also what is known as a vasodilator, and dilates the blood vessels in the brain allowing a greater blood flow. It is known to be beneficial in relation to tasks requiring focused concentration such as mathematical problem solving, and has also been found effective in the treatment of people with poor memory.
Vinpocetine (ethyl apovincaminate) is a derivative of vincamine, obtained by slightly modifying the molecule to produce a commercial form of the alkaloid. This possesses all of the beneficial effects of its precursor, including its positive effects on memory, believed to be due to the stimulation of serotonin production that improves the rate at which the brain can process information. Tinnitus, or ringing in the ears that has severely reduced the quality of life of so many people, can also be treated with vinpotecine.
Its vascodilation effect is thought to be through its action as a phosphodeaterase 1 (PDE1) inhibitor that results in an improvement in the plasticity of neurons. The mechanism is complex, but the end result is an improvement in the cognitive abilities of the subject. This is supplemented by the effect of vinpocetine on the calcium levels in the blood vessels. This renders them more plastic in much the same way that some anti-hypertension treatments work to reduce blood pressure by increasing the plasticity of the blood vessels by modification of their calcium levels. It can also reduce the viscosity of the blood through its action on the “stickiness” of leucocytes and so allow the blood to run more freely through the capillaries of the brain.
These effects have been demonstrated through double blind studies, and there is little doubt that vinpocetine helps to maintain a healthy cerebral circulation. So let’s have a recap on its various effects, and then finish with a summary of the conditions that the alkaloid can be used to treat or improve. The theory and biochemistry behind these effects is known, but is complex, but here are the major actions:
a) It improves blood flow by modifying the calcium content of the blood vessels and so improves their elasticity, hence allowing a freer movement of blood. In effect it helps the blood vessels to dilate easier.
b) It inhibits the enzyme PDE1 and by doing so helps to restore the elasticity of neurons in aging brain cells, allowing them to relax more and operate more effectively.
c) It promotes aerobic glycolysis, and so the rate at which the mitochondria of brain cells produce ATP (adenosine triphosphate) that is the chemical manifestation of energy.
d) It helps to maintain a good supply of glucose and oxygen in the brain to allow (c) to occur.
Not all of these may be separate effects, but the outcome is an improvement in conditions such as short term memory loss, dementia and other conditions associated with a reduction in the blood supply to the brain including Menière’s syndrome and vertigo. There is also evidence that it helps with hearing problems, macular degeneration of the eye, and fatigue.
It is a supplement that should be taken by the elderly to help with age-related memory problems, but has also been found to be beneficial in normal healthy people. The periwinkle extract Vinpocetine has been shown to have benefits, largely through an increase in the blood flow to the brain, and will be of use to anybody suffering from conditions that can be related to a deficiency in their cerebral blood supply.
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Date:
June 26, 2007 02:02 PM
Remineralization is a straightforward procedure. Simply apply a specific fine rock dust (called glacial gravel) to a field, garden, forest, or even a planter. This type of dust creates a broad spectrum of minerals in the soil in a natural balance. Local sources of rock dust are available as well as products that can be purchased. (www.remineralize.org)
Remineralization is also far less expensive and labor intensive than traditional fertilizing and pest control. A ton of rock dust costs anywhere between nothing at all and $8.00 and only needs to be applied every 1 – 10 years, depending on the application. Compare this to chemical fertilizers, which cost over $400.00 per tone and need to be applied at least once each season.
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Date:
June 01, 2005 11:41 AM
Throughout history, minerals were crucial to the growth and success of civilizations. From the iron spear to the silicon chip, elements of the earth have influenced the fate of nations. Today, we’re beginning to appreciate the importance of minerals to the growth and health of the human body – especially in light of so many new challenges to our health. It’s no surprise then that trace minerals are in great demand; after all, our lives depend on them. Due to denatured soils and the widespread use of agricultural chemicals, food plants now contain fewer essential minerals. These precious elements of health are our real wealth, and like a modern gold rush, the search is on for valuable trace minerals. Unfortunately though, there’s a lot of “fools’ gold” on the market. Source Naturals built its reputation with leading-edge formulas that make a difference you can feel. Now, after very thorough research, we are proud to offer COLLOIDALIFE, the finest and safest complete trace mineral formula available today.
The ColloidaLife Advantage
Minerals – the Foundation of Life
As human beings, we are profoundly connected with our world. The elements of this earth become the minerals essential to every cell in the body. The millions of chemical reactions occurring within us each second – as molecules are continually broken down and rebuilt into necessary forms – cannot take place without enzymes; and enzymes can’t work unless they’re activated by the right mineral or vitamin. For example, magnesium is the activator mineral for over 300 different metabolic enzymes that facilitate the biochemical processes of life. Most of us are familiar with the minerals that are found in significant quantities in our bodies. We’re aware of the importance of calcium, magnesium, and potassium. There are, however, other minerals that we need in minute quantities called “trace minerals.” Though less understood, research is revealing the vital role they have in the overall structure and function of the human body. Many people are recognizing the need to supplement their diets with trace minerals such as copper, zinc, chromium, manganese, molybdenum, iodine, selenium, silver, and boron.
Modern Agriculture and Mineral Deficiencies
Minerals cannot be produced by the human body and therefore must be obtained from the diet. However, intense agriculture has depleted the soil of most essential minerals, returning only a few used in fertilizers to stimulate rapid plant growth: nitrogen, phosphorus, and potassium. Consequently few people get anywhere near a hundred percent of the RDA (Recommended Daily Allowances) of minerals (and these RDAs are only the minimum amount needed to avoid a full-blown deficiency condition).
A Superior Solution
The key to formulating colloidal trace mineral supplements is found at the molecular level. Colloids are particles in a solution that are completely dispersed and will not settle out. Many trace mineral products are just water leached through mineral deposits, and contain high levels of undesirable minerals. COLLOIDALIFE is prepared through a proprietary process whereby 20 minerals are individually prepared as colloids. These USP grade minerals are then blended with 52 charged ionic mineral electrolytes derived from highly purified ocean water. This ionic solution strengthens the net surface charge of the colloidal particle, creating a more stable colloid. The trace mineral electrolytes in COLLOIDALIFE are present in extremely small, but optimal quantities that prevent the colloids from precipitating out. Because the ionic matter is easily absorbed and is highly reactive in the body, only trace amounts of the different electrolytes are needed. COLLOIDALIFE therefore provides protection from possible deficiencies while avoiding the possibility of toxicity.
Safety First
Some trace mineral formulas have multi-gram per liter levels of aluminum, iron, or sulfur – much higher than desirable – as well as high amounts of arsenic, cadmium, lead, and mercury. (Although a high level of iron produces an energy rush, in the long run it may promote excessive free radicals.) Because COLLOIDALIFE’s mineral colloids are individually prepared, their quantities are specifically controlled. COLLOIDALIFE contains safe levels of the minerals that should be limited in the diet, unlike simple solutions of earth and water. The ocean water containing the ionic minerals is purified by several procedures that remove any environmental or biological contaminants.
The Ocean Within
The minerals in COLLOIDALIFE emulate the way minerals are carried in the blood and used by the cells: colloidal particles suspended in ionic fluid. Sea water – except for its higher salt content – has a mineral profile very compatible to that of the body’s three fluid systems: blood plasma, lymphatic, and extra-cellular. This similarity underscores our intimate connection to the earth and its oceans. Neutral in taste, Source Naturals COLLOIDALIFE can be held under the tongue for sublingual absorption, or swallowed directly. COLLOIDALIFE is the perfect solution to compensate for a mineral-poor diet that may be limiting your ability to enjoy a healthy and vital life.
ColloidaLife – Mineral Profile*
COLLOI D A L MI N E R A L S
PER TSP: PER TSP:
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Date:
May 26, 2005 10:37 AM
Abstract Objectie :To investigate the effect of vinpocetine on cerebral blood flow (CBF) in the compromised circulation of a stroke affected hemisphere using transcranial Doppler (TCD) and near infrared spectroscopy (NIRS) methods. Methods : 43 patients with ischemic stroke were randomized into vinpocetine (VP) and placebo group in a double blind, placebo-controlled study of the effect of a single-dose i.v. infusion of vinpocetine on cerebral blood perfusion and oxygenation. In the VP group 20 mg VP in 500 ml saline, in the placebo group 500 ml saline alone were administered. The concentrations of oxy-, reduced- and total hemoglobin were measured by NIRS frontolaterally on the side of lesion while the mean cerebral blood flow velocity (CBFV), the pulsatility index (PI) and Doppler spectral intensity (DSI) were monitored by TCD in the middle cerebral artery on the same side. Values were averaged for the first 5 min prior to the infusion and for the last 5 min of infusion and they were compared between groups. Results : The concentration of all three chromophores increased during infusion in the VP group (mean dHbT=1.03, CI95=0.84, P=0.058; mean dHbO=0.92, CI95=0.91, P=0.071; mean dHb=0.10, CI95=0.21, P=0.297). The HbT and HbO showed a substantially smaller increase in the placebo group (mean dHbT=0.31, CI95=0.74, P=0.22; mean dHbO=0.57, CI95=0.80, P=0.094) while the Hb decreased (mean dHb=-0.26, CI95=0.29, P=0.05). Comparing to the placebo group Hb increased significantly in the VP group (P=0.027) while the increase of HbO and HbT did not reach the level of significance (P=0.29 and 0.11). DSI showed a significantly larger increase in the VP than in placebo group (dDSI=25.8 CI95=8.8 [VP]; dDSI=3.3, CI95=3.7 [Placebo], P0.005). The CBFV and PI did not differ significantly between groups. (dVm=5.02.98 cm/s [VP], dVm=4.12.57 cm/s [Placebo], P=0.28; dPI=0.08 [VP], dPI=0.09 [Placebo]; P=0.47). Conclusion :VP increases cerebral perfusion and parenchymal oxygen extraction as well. The increased perfusion was indicated by NIRS and by TCD measurement of DSI while conventional velocity and pulsatility measurements failed to detect theses effects. NIRS is a sensitive, www.elsevier.com/locate/ejultrasou Abbreiations :BP, blood pressure; CI, confidence interval; CBFV, cerebral blood flow velocity; CT, computer tomography; CytO, cytochrome-oxydase; DSI, Doppler spectral intensity; Hb, deoxyhaemoglobin; HbO, oxyhaemoglobin; HbT, total haemoglobin; HR, heart rate; MAP, mean arterial pressure; MCA, middle cerebral artery; MRI, magnetic resonance imaging; NIRS, near infrared spectroscopy; PET, positron emission tomography; PI, pulsatility index; TCD, transcranial Doppler; US, ultrasonography; VP, vinpocetine.
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Date:
May 12, 2005 12:34 PM
Garlic Consumption and Cancer Prevention: Meta-Analyses of Colorectal and Stomach Cancers
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Date:
May 12, 2005 12:18 PM
Garlic and Cancer. A Critical Review of the Epidemiologic Literature
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Date:
May 09, 2005 11:46 AM
Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement.
Heber D, Yip I, Ashley JM, Elashoff DA, Elashoff RM, Go VL.
Center for Human Nutrition, Department of Medicine, UCLA School of Medicine, Los Angeles, CA 90095-1742, USA. dheber@med1.medsch.ucla.edu
BACKGROUND: We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice supplement in an American population consuming a diet similar to the American Heart Association Step I diet using a double-blind, placebo-controlled, prospectively randomized 12-wk controlled trial at a university research center. OBJECTIVE: We evaluated the lipid-lowering effects of this red-yeast-rice dietary supplement in US adults separate from effects of diet alone. DESIGN: Eighty-three healthy subjects (46 men and 37 women aged 34-78 y) with hyperlipidemia [total cholesterol, 5.28-8.74 mmol/L (204-338 mg/dL); LDL cholesterol, 3.31-7.16 mmol/L (128-277 mg/dL); triacylglycerol, 0.62-2.78 mmol/L (55-246 mg/dL); and HDL cholesterol 0.78-2.46 mmol/L (30-95 mg/dL)] who were not being treated with lipid-lowering drugs participated. Subjects were treated with red yeast rice (2.4 g/d) or placebo and instructed to consume a diet providing 30% of energy from fat, <10% from saturated fat, and <300 mg cholesterol daily. Main outcome measures were total cholesterol, total triacylglycerol, and HDL and LDL cholesterol measured at weeks 8, 9, 11, and 12. RESULTS: Total cholesterol concentrations decreased significantly between baseline and 8 wk in the red-yeast-rice-treated group compared with the placebo-treated group [(x+/-SD) 6.57+/-0.93 mmol/L (254+/-36 mg/dL) to 5.38+/-0.80 mmol/L (208+/-31 mg/dL); P < 0.001]. LDL cholesterol and total triacylglycerol were also reduced with the supplement. HDL cholesterol did not change significantly. CONCLUSIONS: Red yeast rice significantly reduces total cholesterol, LDL cholesterol, and total triacylglycerol concentrations compared with placebo and provides a new, novel, food-based approach to lowering cholesterol in the general population.
Publication Types: Clinical Trial Randomized Controlled Trial
PMID: 9989685 [PubMed - indexed for MEDLINE]
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Date:
May 09, 2005 11:33 AM
Department of Biochemical Pharmacology, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100083, China.
Long-term effects of Cholestin (Monascus purpureus rice; red yeast rice) on serum lipids and severity of atherosclerosis were examined in rabbits fed for 200 days on a semi-purified diet containing 0.25% cholesterol. Serum total cholesterol was 25 and 40% lower, respectively, in rabbits fed 0.4 or 1.35 g/kg/day of Cholestin (Monascus purpureus rice; red yeast rice) compared to controls. This treatment also lowered serum LDL cholesterol. This 200-day treatment significantly reduced serum triglycerides and atherosclerotic index (ratio of non-HDL-cholesterol to HDL-cholesterol). Although similar reductions of total, LDL-cholesterol and triglycerides were observed, a parallel group of rabbits fed lovastatin (0.0024 g/kg/day) failed to reduce the index significantly. Apolipoprotein A(1) was increased and apolipoprotein B was reduced in all treatment groups. Severity of atherosclerosis was reduced significantly in all treatment groups. The sudanophilic area of involvement was 80.6% in controls, and reduced significantly; to 30.1% on the low dose (Monascus purpureus rice; red yeast rice), and 17.2% on the high dose. Lovastatin reduced severity of lesions by 89% (sudanophilia) and 84% (visual). Visual grading of lesion severity showed reduction by 38% and 68%.
PMID: 12873712 [PubMed - indexed for MEDLINE]
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