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Study proves the gastrointestinal benefits of curcumin Darrell Miller 12/13/18
What Is Artemisinin? Darrell Miller 4/28/14
Can DMAE Help Memory And Mood? Darrell Miller 12/19/13
How Do I Use Phytoestrogen And Progesterone Creams For PMS? Darrell Miller 9/22/11
Using SAMe for Depression Darrell Miller 6/4/11
Doctor’s Corner - Relora: Minimizes Stress-Induced Eating Darrell Miller 8/9/06
7-Syndrom Healing and 5-HTP Darrell Miller 6/7/06
Omega-3 Fish Oils “Super Supplement of the Sea” Darrell Miller 1/3/06
JOINT HEALTH Darrell Miller 12/22/05
7-Keto - Anti-Aging and Antioxidant Protection Darrell Miller 12/18/05
Nutrition Insurance .... Darrell Miller 10/21/05
Fight Hay Fever - Help Your Sinus... Darrell Miller 7/11/05
Effects of a novel formulation of essential oils on glucose–insulinmetabolism in diabetic Darrell Miller 5/18/05
Acute administration of red yeast rice depletes tissue CoQ10 Darrell Miller 5/13/05
Re: Sulforaphane Stimulates the Body's Cancer-Fighting Enzymes Darrell Miller 5/13/05
Long Jack PowerMax 200 from Action Labs Darrell Miller 5/10/05
Re: Read more on how to Lower Cholesterol safe and naturally! Darrell Miller 5/9/05



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Study proves the gastrointestinal benefits of curcumin
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Date: December 13, 2018 09:32 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study proves the gastrointestinal benefits of curcumin





There are a lot of gastrointestinal benefits of curcumin that are being proven by studies. Within a human body, a gastrointestinal track is extremely important. Of course, it is very useful when trying to allow the body to get rid of the toxins that are in your bodies. Therefore, making sure that you are doing all the right things to keep the gastrointestinal track healthy is very important. Some people do not realize the importance until it is too late.

Key Takeaways:

  • the Journal of Medicinal Food published findings adding to the long list of positive health benefits attributed to curcumin, a component of turmeric.
  • A healthy, full-functioning digestive system has duel functions, of first extracting essential nutrients from food and then releasing toxins and waste from the body.
  • Data proved conclusively that gastric emptying was improved for mice subjects administered a 200mg per day dose of curcumin.

"To uncover the benefits that curcumin has on gastrointestinal function, the researchers conducted an in vivo and an in vitro study."

Read more: https://www.naturalnews.com/2018-11-20-the-gastrointestinal-benefits-of-curcumin.html

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What Is Artemisinin?
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Date: April 28, 2014 06:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Artemisinin?

arteminisin plantArtemisinin health benefits

Long known as an imposing enemy to malaria and other significant parasites, studies indicate that Artemisinin could assume a useful part in cancer medicines. Uncovered to be a compelling malaria medication many years prior by Chinese botanists, the most recent century has seen that artemisinin is utilized productively within western pharmaceutical. Not just artemisinin treat the worldwide executioner malaria, yet late studies are additionally revealing to its medicinal viability extending from malaria to cancer.

The concentrate is from the plant Artemesia annua also known as sweet wormwood has numerous diverse aspects to determined medicine.

How arteminisin works

It's exceptionally extraordinary in its sub-atomic structure in that it has two oxygen particles joined together by what's known as an 'endoperoxide span'. Why Artemisinin utilization are so wide is unequivocally on account of this extension and its unique atomic structure. Its piece implies it responds with particles with a high iron substance, for example, malaria parasites and cancerous tumors. Upon contact with infected cells (with this high iron substance), its system of activity is to structure free radicals. These free radicals are poisonous to the respectability of the attacking cells, separating them and in the end leaving the contaminated cells devastated.

It's exactly in view of Artemisinin's impact on infections with a high iron substance that is incited enthusiasm toward wormwood for cancer medicine.

The most well-known motivation to take Artemisinin is as an influential malaria medicine. An every day course of Artemisinin 200mg is suggested for those in zones with a high danger of malaria and despite the fact that there are numerous malaria pills available, the abundance of accessible Artemisisin data exhibits its adequacy and adaptability above other hostile to malarial medications.

Whether its being utilized as a malaria medicine or utilized as a component of cancer medicines, Artemisinin is not difficult to take and distinguished as a capable, all inclusive and common wormwood-determined pharmaceutical.

What is Artemisinin used for?

Individuals the world-over take Artemisinin as against malaria prescription. As malaria is a standout amongst the most productive health issues around the world (particularly in creating nations), its profits to worldwide health are enormous.

It's effective to the point that it structures the fundamental malaria-battling properties of various mix malaria medicines. That is also its part as the lead executioner of parasites and human blood flukes. It's the best medicine against schistosomes, the second-most productive parasitic disease, after malaria.

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Can DMAE Help Memory And Mood?
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Date: December 19, 2013 07:23 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can DMAE Help Memory And Mood?

moodDMAE

Do you ever feel like you are experiencing lapses in memory or you have a low general mood? There is evidence that DMAE might be able to help with both memory and mood. DMAE occurs naturally in the human brain. When we take supplemental amounts of the compound, brain function effects can be seen.

DMAE as a Supplement

It is thought that the supplement works by increasing the speed of the brain's turnover and synthesis of a neurotransmitter called acetylcholine. This neurotransmitter plays a strong role in maintaining general mental ability. It also works at supporting a stable, healthy memory in older adults. It is also believed that DMAE might work by stopping choline metabolism. This allows the free choline to gather in the blood, go into the brain, and stimulate the cholinergic receptors.

A French double-blind study was performed to measure how much of an impact the supplement DMAE has on both mood and vigilance. Four of the subjects were categorized as having anxiety, and four other subjects were the controls. They were each given 1200mg of DMAE over the course of 5 days. These subjects were measured daily for their EEG and convergence of the inter hemispheres of the brain. In the case of the four subjects that were given the supplement, progressive sync of the two brain hemispheres was found. This is correlated with increased neuromotor control, increased verbal memory, improvement in behavioral tasks, as well as better control of anxiety.

Another use for DMAE worth mentioning is its affects on learning deficiencies like ADD or hyperkinesia. Many doctors prescribe amphetamines for conditions like this, but DMAE has also proven useful. According to studies, hyperactivity and irritability decrease, and scholastic ability improves from supplementing with DMAE.

In addition to improving these conditions there is evidence that DMAE can improve life span, IQ, and motor mechanisms. It is very important to take the correct dosage of DMAE. I would start with taking 200-400mg first, and work your way up from there.

Sources:

  1. //en.wikipedia.org/wiki/Dimethylethanolamine
  2. //www.life-enhancement.com/magazine/article/105-presence-of-mind-dmae-the-mood-elevating-smart-nutrient

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How Do I Use Phytoestrogen And Progesterone Creams For PMS?
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Date: September 22, 2011 11:04 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Do I Use Phytoestrogen And Progesterone Creams For PMS?

Overview

If you are a guy who had encountered women you probably would have heard about PMS. It is something that we as men are familiar with because often times, about once a month our female acquaintances would let us know that they should be allowed to act silly and have their way for the next few days all because they are experiencing PMS but is there truth to it? Let’s try to take a more scientific approach because my guess is, it is more serious than we know.

PMS

Premenstrual syndrome (PMS) is defined by strong and consistent mood swings, tender breasts, fatigue, depressions, food cravings and irritability just to name some of the more common symptoms. Commonly this peaks around the late 20’s and early 30’s for females and it is a serious issue. It is not the kind of juvenile reason for tantrums that young female kids might lightly throw around. These symptoms can cause serious discomfort and many changes in the sufferer’s lives and at times in certain months it will be pretty intense and unnoticeable in some. It also happens in a predictable pattern which is one upside to allow the patient to prepare for it and can figure out certain ways to counter the effects so as to not allow PMS to take control of your life.

Phytoestrogen And Progesterone Creams

First off let look at some details about these substances. Phytoestrogen are chemicals that are derived from plants and have the primary property of having the ability to mimic estrogen in the human body which is the primary sex hormone in women. Estrogen on the other hand is the real thing and is a hormone manufactured primarily in the ovaries with an essential responsibility of initiating and maintaining proper menstrual cycles in women.

Although this hormone can also be found in the male’s body we produce it at a lesser degree. Studies have shown that estrogen is an important factor in women’s reproductive cycles unlike men which does not really have much use for it and aims to keep the levels of this hormone down as it may cause more feminine bodily changes in men. With women however, supplementation with estrogen has been used to treat reproductive cycle issues so it is no surprise that these hormones are being incorporated into cream products to aid in PMS relief and how you use it depends on your specific cycle.

Some common guidelines is to use of about 100 to 200mg a day and it terms of when, it shall depend on the length of a female’s cycle. As a general rule though it should be taken 14 days prior to ovulation if the specific ovulation date is not known as ovulation starts fourteen days before bleeding starts. If no ovulation happens or you don’t have a period, use a 28 day cycle as a guide and choose any day to start. It is important that this is done before ovulation so it does not interrupt the body’s natural process of ovulation and hormone production.

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Using SAMe for Depression
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Date: June 04, 2011 10:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Using SAMe for Depression

SAMe, or S-adenosyl-L-methionine, has been promoted for the treatment of depression and various physical conditions. It is believed to help improve the feeling of well-being and mood, and its use in treating depression is likely connected with that.NOW - SAM-E 2X 200mg   60 TABS 1 Several studies have been carried out, administering SAMe both orally and parenterally with promising results. Some that use it believe it more effective than the more common antidepressants, and unlike most of these it has very few side effects and a very quick onset of action: around 2 weeks in comparison to a month for most others.

A typical study of the many carried out involved 30 subjects taking regular antidepressants but still suffering depression. They were given 0.8 grams SAMe for 2 weeks and then 1.6 grams for 4 weeks. Improvement was obtained in 50% cases and complete remission of symptoms in a total of 43% of the subjects. In another test on 28 subjects, the improvement equaled that of prescription antidepressant drugs.

These significant findings render this over the counter supplement (in the USA) worth taking for anybody that has either no effective help from their regular treatment, or would prefer to try a natural biochemical than a synthetic drug for their condition. You are recommended to refer to your doctor, however, if you intend changing your treatment.

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Doctor’s Corner - Relora: Minimizes Stress-Induced Eating
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Date: August 09, 2006 01:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Doctor’s Corner - Relora: Minimizes Stress-Induced Eating

Relora is a proprietary all-natural botanical product developed by Next Pharmaceuticals, Inc. it contains ingredients extracted from two plant species that have been used in traditional Chinese herbalism for over 1500 years. These are patented extract from Magnolia officinalis (US Patent No: US 6,582,735) and a patent-pending extract from Phellodendron amurense.

Relora helps relieve stress, anxiety and minimize stress-induced eating, which in turn may help to produce weight loss when used as part of a healthy diet and exercise plan. The research and development of Relora involved sophisticated testing and screening for ingredients that have anti-anxiety properties, but no daytime sedative effects. Initially, investigators tested the Magnoliaceae plant family as a lead source of new anti-anxiety products. Scientists first focused on two phytochemicals on constituents in the plant that have “bio-activity” (work positively on the body)—magnolol and honokiol. Through a series of studies, it became clear that Relora was a safe and effective formulation.

Relora works with the body’s natural chemistry to maintain normal levels of stress hormones. These hormones not only affect emotional well-being, but can also have a major impact on appetite and how the body stores and metabolizes fat. By working to re-establish a stable balance of these hormones, relora can help break the stress/weight cycle and restore optimum health to the mind and body.

In addition to normalizing stress hormones, Relora has been shown to control anxiety and the symptoms associated with it: irritability, emotional ups and downs, restlessness, tense muscles, poor sleep, fatigue and difficulty concentrating. Daytime sedation often occurs with products that induce relaxation. Not with Relora! This breakthrough botanical provides all the anti-anxiety benefits without inducing daytime sedation. In central nervous system receptor binding assays, the plant extracts in Relora bind to several important targets associated with anxiety. Also if interested, the bark of magnolia officinalis has been used in traditional Chinese herbalism for centuries for stress induced muscular tension.

Relora, Stress and Weight Loss

Stress is reported to play a significant role in a wide variety of health conditions. Recent work with the National Institutes of Health (NIH) and other major research centers has demonstrated that stress is a significant contributor to immune dysfunction, cardiovascular challenges, other age-related imbalances, and excess body fat. This type of fat is related to stress-induced hormone imbalances, especially imbalances of the hormones cortisol and DHEA. Until now, the only course of action for losing this fat has been stress reduction with exercise and diet, and anyone who has attempted diet and exercise alone often encounters a long, troublesome road. Relora may help the body normalize cortisol and DHEA levels in stressed individuals while inducing relaxation, and act as an aid in controlling weight and stress-related eating.

The increase in cortisol levels signals the brain that the body is in stress, causing food cravings, especially for high-fat, high-sugar foods. These foods, in turn, cause additional stress, thereby fueling the stress-cortisol cycle. Eventually, more fat is stored than the body needs unless sufficient exercise is in place to compensate, or the stress is reduced.

The ingredients in Relora are key supplements that help the adrenal glands to “come back to life” by reducing the excessive stress hormone response in the body and reducing carbohydrate craving behavior.

Results from Human Trials with Relora

Relora was tested at the Living Longer Institute in Cincinnati, OH and found to be safe, effective, rapid acting, non-sedating dietary supplement that helps control occasional mild anxiety. Three hundred forty five female subjects were administered Relora for 2 weeks. The dosage was 200mg of Relora three times daily. Eighty nine percent of the subjects reported that Relora helped them relax, while 78% found Relora to help prevent stress-related eating.

A second trial was undertaken at the Living Longer Institute to measure cortisol and DHEA levels in patients with mild to moderate stress. Elevated cortisol levels and depressed DHEA levels are associated with chronic stress. A two week regimen of Relora produced a significant increase in salivary DHEA (227%) and a significant decrease in morning salivary cortisol levels (37%). These findings support Relora’s ability to relieve stress and its potential role in weight control and stress-related eating behavior.

A third study was completed in late 2002 that evaluated Relora on its ability to improve snacking habits in people who snack on sweets or eat salty snacks when they are under excessive stress. Forty nine subjects were evaluated and it was found that Relora cur sweet snacking in the sweet cravers by 75%! It cut snacking on salty snacks by 50%. Seventy three percent of all individuals in the study reported feeling less stressed while taking Relora.

A double-blind placebo-controlled study was completed in January, 2004. forty premenopausal women were evaluated for stress, anxiety, food intake and weight management. Relora significantly reduced anxiety and prevented weight gain. A significant weight gain occurred in the placebo group while either now weight gain or weight loss occurred in the Relora group.

Suggested Use and Safety

Relora is designed for adults. The suggested daily dose is 1 capsule (250mg) 2 – 3 times per day. Relora is not recommended for persons under the age of 18. if you are pregnant, nursing or taking a prescription drug, consult a health practitioner prior to use.

Dr. James B. LaValle, R.Ph., N.M.D., C.C.N. is a licensed pharmacist (University of Cincinnati College of Pharmacy), certified clinical nutritionist (International & American Associations of Clinical Nutritionists), and doctor of naturopathic medicine (Central States College of Health Sciences, IAACN), with more than 18 years clinical practice experience in the field of natural therapeutics and functional medicine. Dr. LaValle is in clinical practice at the Living Longer Institute, a comprehensive wellness, prevention, and early detection program he co-founded. He sits on various scientific advisory boards within the dietary supplement industry. LaValle is also an adjunct professor in the college of pharmacy at The University of Cincinnati and serves as a preceptor in the Department of family Medicine, University of Cincinnati College of Medicine.

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7-Syndrom Healing and 5-HTP
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Date: June 07, 2006 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Syndrom Healing and 5-HTP

Boomer Breakthrough – Keeping in the Game

If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves.

Mood, Anxiety and Depression

Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use.

How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels.

Serotonin the Antiaging Neurotransmitter

Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients.

Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period.

5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin.

It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia.

Pain, Per-menopause and PMS

5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants.

Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability.

Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller.

Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety.

Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain.

Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.



--
Buy Books at Vitanet ®

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Omega-3 Fish Oils “Super Supplement of the Sea”
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Date: January 03, 2006 08:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega-3 Fish Oils “Super Supplement of the Sea”

  • Enteric Coated Molecularly Distilled Omega-3
  • PURIFICATION METHOD Molecularly distilled as pharmaceutical DHA 250 mg Softgels
  • PURIFICATION METHOD Molecularly distilled and purifi ed MaxEPA 1000mg Gels
  • PURIFICATION METHOD Advanced fi ltration via active carbon treatment Omega-3 1000mg, 180/120
  • PURIFICATION METHOD AAT (Advanced absorbent technology) SuperEPA 1200mg 360/240
  • PURIFICATION METHOD AAT with vacuum molecular (MD) distillation Super Omega 3-6-9 1200mg
  • PURIFICATION METHOD Advanced absorbent technology Molecularly Distilled Lemon Liq.
  • PURIFICATION METHOD Molecularly distilled as Pharmaceutical

References
1.) Vanderhaeghe L, Karst K, Healthy Fats for Life; Quarry Healthy Books. 2003
2.) Stoll AL, Severus WE, Freeman MP, et al. Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. Arch General Psychiatry. 1999
3.) Ascherio A, Rimm EB, Stampfer MJ, et al. Dietary intake of marine n-3 fatty acids, fi sh intake, and the risk of coronary disease among men. New England Journal Med. 1995
4.) Challem J, The Infl ammation Syndrome; John Wiley and Sons Publishing. 2003
5.) Giampapa R, Pero R, Zimmerman M, The Anti-aging Solution; John Wiley and Sons Publishing, 2004
6.) Croft J, Health from the Seas, Freedom from Disease; Vital Health Publishing. 2003

*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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JOINT HEALTH
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Date: December 22, 2005 09:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: JOINT HEALTH

Glucosamine & Chondroitin - JOINT HEALTH

Everyone old enough to walk appreciates the value of fl exibility and ease of movement. Unfortunately many of us take such good things for granted. A famous folksinger sang, “You don’t know what you’ve got till it’s gone.” That’s certainly true for millions of Americans who live with stiff and uncomfortable joints.

Fortunately there are a number of nutrients available that provide the vital components of healthy joint structure and function and ease of mobility. These nutrients are referred to as “chondroprotective agents,” and include glucosamine and chondroitin, which supply the raw material necessary to produce new cartilage, and may even help rebuild worn cartilage. Other chondroprotective nutrients and herbs, like Cetyl Myristoleate, MSM, and Boswellin, work synergistically with glucosamine and chondroitin and further support normal joint function To understand how chondroprotective agents work, one must fi rst understand how joints work. The key element in human joints is articular cartilage, the shock-absorbing tissue that connects two bones together and allows pain-free movement. Articular cartilage is comprised of two different molecules, collagen and proteoglycans, with the remainder composed primarily of water (65-85%). Collagen, a protein that binds tissue together, provides elasticity. Proteoglycans, composed of sugars and protein, absorb water, which provides lubrication and resiliency, nature’s shock absorber for your joints. Both compounds are produced by chondrocytes, caretaker cells responsible for the formation and maintenance of cartilage. A defi ciency in any one of the above constituents will increase the likelihood of wear and tear on articular cartilage, which can eventually lead to compromised joint function.

Glucosamine and chondroitin are safe, natural and effective nutrients that support healthy joint function by supplying the materials needed to produce collagen and proteoglycans.

GLUCOSAMINE

Glucosamine is composed of glucose (a sugar) and glutamine (an amino acid). It is utilized by chondrocytes to form glycosaminoglycans (GSG) and proteoglycans (PG). Both of these constituents attract and bind water into cartilage, increasing resiliency. Research indicates that glucosamine may actually help your body repair damaged or eroded cartilage. A number of studies have been conducted on glucosamine sulfate and glucosamine hydrochloride, with a preponderance of positive results. Glucosamine sulfate is considered the more effective of the two. One study from the University of Liege in Liege, Belgium studied the effects of glucosamine sulfate on 212 patients with knee osteoarthritis. Participants took either 1,500 mg glucosamine or a placebo once daily for three years. The study compared joint-space width at enrollment, one year, and at the study’s conclusion.

The 106 patients on placebo had a progressive jointspace narrowing, while participants taking glucosamine experienced no significant joint-space loss, indicating glucosamine may benefi cially modify cartilage structure.3 A study published in the journal Osteoarthritis and Cartilage in 1998 investigated the in vitro effects of glucosamine sulfate on proteoglycan and collagen production by chondrocytes taken from osteoarthritic articular cartilage. The results showed “a statistically signifi cant stimulation of PG production by chondrocytes from human osteoarthritic cartilage cultured for up to 12 days in 3-dimensional cultures.” 4 Another study from Italy enrolled eighty inpatients with established OA. They received either 1,500 mg of glucosamine sulfate or placebo daily for 30 days. The patients treated with glucosamine sulfate experienced a reduction in symptoms almost twice as large and twice as fast as those receiving placebo. Researchers also used electron microscopy of patient’s articular cartilage to support this hypothesis. Patients who received glucosamine sulfate showed a picture more similar to healthy cartilage. The researchers concluded that glucosamine sulfate tends to rebuild damaged articular cartilage and restore articular function.5

CHONDROITIN

Chondroitin is classifi ed as a glycosaminoglycan. It bonds with collagen to form the basis of connective tissue. Chondroitin helps attract fl uid into proteoglycans, thereby bringing nutrients into cartilage and providing shock absorption. While glucosamine helps manufacture and maintain cartilage, chondroitin keeps cartilage from becoming malnourished. Chondroitin works synergistically with glucosamine, and these two nutrients form the basis of most joint health supplements on the market today. A 6-month randomized, multi-center, double-blind, doubledummy study published in 1996 compared the effectiveness of chondroitin versus a popular non-steroidal anti-infl ammatory drug (NSAID) in patients with knee osteoarthritis (OA). One hundred and forty-six patients with knee OA were recruited and separated into two groups; an NSAID group and a chondroitin sulfate (CS) group. The NSAID group was given the NSAID and a placebo for the fi rst month, then placebo alone for months 2-3. The CS group was given the NSAID and CS for the fi rst month, and then CS alone for months 2-3. Both groups were then given 1200mg of CS for months 4-6. “Patients treated with the NSAID showed prompt and plain reduction of clinical symptoms, which, however, reappeared after the end of treatment; in the CS group, the therapeutic response appeared later in time but lasted for up to 3 months after the end of treatment. CS seems to have slow but gradually increasing clinical activity in OA; these benefi ts last for a long period after the end of treatment.”6

NOW® Foods is your source for natural joint support products. Our Extra Strength Glucosamine & Chondroitin is one of our best-selling products, and we also have combination supplements that include MSM, Concentrace® minerals, and more. We also carry both glucosamine and chondroitin as separate products, as well as in powder and lotion forms.

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7-Keto - Anti-Aging and Antioxidant Protection
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Date: December 18, 2005 09:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Keto - Anti-Aging and Antioxidant Protection

7-Keto

“Anti-Aging and Antioxidant Protection”

The Fountain of Youth Discovered in Wisconsin

It turns out that Ponce de Leon was looking in the wrong place for the fabled Fountain of Youth. It was recently discovered – in Wisconsin! And it turns out that the Fountain of Youth isn’t really a fountain – it’s a biological compound produced in our own bodies. This compound is extremely important for the growth and development of the human body, and, as the body’s production of this substance decreases with age, the signs of aging begin to appear – weight gain, wrinkled skin, loss of muscle, loss of cognitive function, and loss of libido.

This biological Fountain of Youth was discovered by Dr. Henry Lardy and associates at the Institute for Enzyme Research at the University of Wisconsin. It’s called 7-Keto™, a metabolite of a hormone produced by the adrenal glands called DHEA (dehydroepiandrosterone). Research on 7-Keto™ indicates that it may work through a number of pathways to combat the signs of aging. Helping the body maintain a healthy weight as we age greatly improves overall health and longevity and is one of the strongest benefits discovered for 7-Keto™ to date.

Unfortunately, because 7-Keto™ is a metabolite of DHEA, whose levels decline as we age, so to does this wonderful, natural bio-nutrient. Scientists originally looked to DHEA for improved cardiovascular vitality, and strengthened immune and brain function3. Researchers believed that declining DHEA so profoundly impacted our bodies that it could be partly responsible for the effects of aging. They hypothesized that supplementation with DHEA could sustain hormone levels and stave off many of the degenerative changes we collectively call aging. But there was a catch. Because DHEA is converted into sex hormones, people taking supplemental DHEA would sometimes experience the frightening, unwanted side effects associated with hormone supplementation.

In 1989, Dr. Lardy and his colleagues set out to solve the mystery of eliminating DHEA’s side effects by examining all of the constituents that make up DHEA. Ten long years of research unearthed hundreds of DHEA derivatives, which were developed and tested continuously, until one derivative rose above all the others – a metabolite that was incredibly bio-active and far more promising than any other substance they’d tested. That metabolite is 7-Keto™. 7-Keto™ outperformed DHEA and other metabolites in immune modulation, memory enhancement and thermogenesis and, more importantly, without any adverse side effects3.

The most significant benefit of 7-Keto™ supplementation is its ability to support healthy body weight. Obesity is a major contributing factor in a number of serious medical conditions. A recent study assessed the effectiveness of 7-Keto™ on weight loss and body fat loss. Participants were divided into two groups; one group received 100mg of 7-Keto™ twice daily and the other a placebo. Both groups exercised three times per week. At the end of the study, researchers noted a statistically significant reduction in body weight and body fat only in the 7-Keto™ group. Researchers concluded that 7-Keto™ was three times more effective than diet and exercise alone in promoting weight and fat loss1,2,7. Preliminary research also indicates that 7-Keto™ may support healthy immune and nervous systems. One study measured the effects of 7-Keto™ on memory function. Subjects were given a single dose of a substance that inhibits nerve cell communication and causes shortterm memory loss. Afterwards subjects were given a single dose of 7-Keto™. Results showed that 7-Keto completely reversed the memory impairment, suggesting that 7-Keto™ supports memory retention6.

Another study gauged 7-Keto™’s ability to support immune system function. Interleukin 2 (IL2) is a substance produced by T lymphocytes that causes an increase of disease fighting white blood cells. White blood cells were taken from healthy volunteers and introduced into a solution that contained 7-Keto™ for 24 hours. When the cultures were tested for heightened IL2 production. 7-Keto™ was shown to augment IL2 production by a statistically significant 68%4.

NOW® 7-Keto™ is a well-researched and patented form of this amazing product that’s supplied by the Humanetics Corporation. Humanetics 7-Keto™ has been proven safe and well-tolerated in doses up to 200mg5. Research is clear, the rate at which we age can be influenced by the diet and lifestyle choices we make. One very smart choice would clearly be adding NOW 7-Keto™ to your diet.

References

1) 7-Keto™: The Key to Healthy Aging – Scientific Support; Humanetics Corporation, 1999
2) Garbis, Spiro; 7-Keto™ DHEA; internal meta-analysis, 2000
3) Sahelian, Ray, M.D.; DHEA: A Practical Guide; Avery Publishing, 1996
4) Lardy, H. et.al. Dehydroepiandrosterone and 7-Keto™ DHEA Augment Interleukin 2 (IL2) Production by Human Lymphocytes In Vitro, 5th Conference on Retroviruses and Opportunistic Infections, February 1-5, 1998, Chicago, IL
5) Davidson, M.H. et. al. Clinical Safety and Endocrine Effects of 7-Keto™ DHEA; Presented at Experimental Biology 98 (Conference), April 19-22, 1998, San Francisco, CA
6) Shi, J. et. al. The Effect of 7-oxo- DHEA acetate on memory in young and old C57BL/6 mice; Steroids 65 (2000); 124-129
7) Colker, C. et. al. Double-Blind, Placebo-Controlled, Randomized Clinical Trial Evaluating the Effects of Exercise Plus 3-Acetyl- 7-oxo-dehydroepiandrosterone on Body Composition and the Endocrine System in Overweight Adults; Journal of Exercise Physiology online; Vol. 2, No. 4, October, 1999



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Nutrition Insurance ....
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Date: October 21, 2005 10:25 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nutrition Insurance ....

Nutrition Insurance

All authorities agree that taking prenatal vitamins is a smart idea. Especially important nutrients include:

-Folic Acid. This B vitamin helps prevent neural tube birth defects such as spina bifida, in which a malformed spinal cord can cause everything from fluid on the brain to paralysis. “The great news is that supplemental folic acid decreases the risk of neural tube defects pretty significantly,” says Higdon. “It’s recommended that women who are planning to become pregnant take a supplement that supplies 400 mcg.” Low folate is also associated with high levels of metabolic byproduct called homocysteine; it’s not clear whether high homocysteine is a symptom of folate deficiency or a cause of birth defects. To help folate control homocysteine, add vitamins B-6 and B-12 to your regimen, especially if you are a vegan.

-Iron. Iron deficiency is the most common micronutrient deficiency in the US, especially among women of childbearing age, and “has been associated with poor child development after birth along with increased risk of miscarriage and premature delivery,” according to Higdon. “Also, if you’re deficient you’ll get really tired-you get less oxygen delivered to your tissues an the baby’s” A supplement should supply 30mg; vegetarians have to pay particular attention to their iron levels. Eating foods rich in vitamin C can make it easier to absorb iron, as can eating such fermented soy goodies as tempeh and miso.

-Calcium. Building baby’s bones requires plenty of calcium; Jones and Hudson recommend getting 1200mg a day. If you are lactose intolerant-that is, you can’t properly digest milk products-they suggest you “try yogurt made with live active cultures, whose bacteria releases lactose-digesting enzymes.” Supplemental calcium is another option, preferably in gluconate or chelate form for better absorption. (Calcium can also help cut the leg cramps caused by the pressure of a growing baby.)

-Vitamin D. It doesn’t matter how much calcium you take if you’re not getting enough of the vitamin D that lets your body utilize calcium properly. “Vitamin D deficiency is increasingly common,” says Higdon, “and the RDIs (Reference Daily Intakes) might not be high enough for people who don’t get sun exposure.” Spending 15 minutes a day in the sun can restore your body’s supplies, but “the farther north you live, the longer that period in the winter you can’t make vitamin D, and it’s actually not in too many foods.” Taking 400 IU daily can make up the shortfall.

Believe it or not, iodine deficiency is a growing concern in the US as people cut back on salt, which is commonly fortified with iodine. Higdon says that most prenatal vitamins contain 150mcg.

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Fight Hay Fever - Help Your Sinus...
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Date: July 11, 2005 09:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Hay Fever - Help Your Sinus...

HANDLING SPRING(HAY)

The National Institute of Health’s branch of Allergy and Infectious Diseases re p o rt that 40 to 50 million Americans suffer from allergies in one form or another. Many experience food allergies that a re treated somewhat diff e rently from hay fever allergies. Hay fever comes from airborne allergens, generally from pollen or pollutants.

The symptoms of allergy occur when an immune system is overactive. The immune system often recognizes something as foreign and treats it as foreign by attacking it, when in fact it really isn’t a substance the body should be concern e d with. This over-activity of the immune system leads to the release of substances including histamine that cause the symptoms of hay fever.

The most common symptoms include a runny nose and itching eyes and scratchy throat. Sometimes, an allergy will precede a sinus infection by causing swelling in the nasal membranes preventing fluids f rom exiting the sinus passages. An infection then ensues. However, most people who feel pressure over their sinuses, never develop an infection and so can be adequately treated with the supplements mentioned here. Many people experience a tickle or a shallow cough that comes from the throat rather than the lungs. They may also experience a change in emotions, becoming quite irritable or moody.

These airborne allergies can often be g rouped by season. Those people sensitive to tree pollens usually have more severe allergies in the springtime. Those sensitive to grasses are often worse in mid-summer. Those allergic to weeds have their symptoms peak in the fall. There are some unfortunate people who have allergies all summer long who may be allergic to a few plants in each group. Those who have symptoms of allerg i e s all winter long probably are allergic to molds and mildew or household animals and dust mites. On occasion, it takes a real detective to determine from where the allergies come.

There are several methods used to diagnose a cause of an allergy. In a scratch test, drops of an allergen are put on small scratches on the arm or the back. Are action is considered positive if swelling or redness occur around the scratch. A blood sample can also be used to meas ure antibody response to certain allergens. It is often helpful to determine the allergen which cause the hayfever to reduce the symptoms. There are also practitioners who use kinesiology or electronic devices to determine the cause of allergies.

The most common treatment of allergies is with antihistamines. Their side effects include drowsiness and drying of the mucous membranes of the nose and mouth. Many of the newer prescription antihistamines don’t cause drying but often have serious drug interactions and the consumer must be very careful in combining the prescription antihistamines with antifungal drugs, and blood thinning as well as asthma medication. There are some natural products that can be taken to decrease allergy symptoms. They are often equally effective without the side effects of antihistamines.

QUERCETIN

One of the more popular is quercetin. Quercetin is a bioflavonoid found in red apples, red onions, brussels sprouts, kale, peas, bell peppers, pears and asparagus. It is also found in bee pollen and propolis, two plant materials found in the beehive. It is possible to consume a fair amount of quercetin through your diet. If you have allergies, however, diet is often not enough and you may need a supplement to get enough quercetin to ontrol your symptoms. It appears quercetin decreases allergic symptoms by stopping the release of histamine. If you start taking quercetin and other nutritional supplements I will mention below before an allergy attack, they are likely to be more effective. However, don’t let that discourage you from taking them even after the symptoms have started. A common dose is 300mg to 600mg per day.

BROMELAIN

Bromelain is a nutrient often extracted f rom pineapple. Found in many digestive formulas, it is an enzyme that helps absorption. If it is found in a combination formula, chances are, it is there to help with the absorption of the other nutrients such as quercetin. Bromelain also has an anti-inflammatory effect. When someone develops allergy symptoms, part of the reason is due to the inflammatory response to substances such as histamine that are released as the allergy takes hold. This causes inflammation in the tissues which then manifests with redness and swelling.

VITAMIN C

Vitamin C is useful in many conditions including hay fever. Higher doses are often required in the treatment of allergies: 2,000mg is beneficial and you can take up to 4,000mg or more during acute symptoms. It also stabilizes capillaries, reducing the swelling in the throat, nasal passages and around the eyes. If you are taking a multi-vitamin or a combination product that contains Vitamin C, I still recommend additional supplementation.

NETTLE (URTICA DIOICA)

Stinging nettle is probably a plant many a re familiar with, especially if it has come into contact with your skin, but it also has an historical use in the treatment of allergy. In fact, in double blind studies it was shown to decrease the symptoms of allergy, specifically runny nose.

EPHEDRA (MA HUANG)

The active component of the ephedra herb is ephedrine, an alkaloid. It is used in OTC asthma medication. As a natural herb, ephedra in small doses can be v e ry useful in decreasing the symptoms of colds, asthma, cough and in this case, hay fever. It is in many Chinese and American formulas that I use and I feel v e ry comfortable using 100mg to 200mg of ephedra that contain small doses of 2.5mg to 8mg of ephedra alkaloids per day. I feel comfortable using dosages of up to 15mg of ephedra alkaloids .

FEVERFEW

Feverfew is another herb with a variety of uses. You will find it in headache formulas, in fever reducing formulas, and many hay fever formulas. Like bromelain, it has an anti-inflammatory effect and reduces the swelling that occurs during a hay fever attack.

Homeopathic formulas can also be useful to reduce hay fever. There is no re ason why the herbs I’ve mentioned cannot be combined with homeopathic formulas. You may want to take them at separate times of the day.

So, if you suffer from hay fever, don’t give up. You can use these nutrients singly or in combination. You can take a formula that contains all of them and then add to that additional vitamin C for instance, or additional nettle. It may require trial and error to find the right amounts in combination that will work for you.



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Effects of a novel formulation of essential oils on glucose–insulinmetabolism in diabetic
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Date: May 18, 2005 09:20 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Effects of a novel formulation of essential oils on glucose–insulinmetabolism in diabetic

Background: Insulin resistance and its most severe form type 2 diabetes mellitus are rapidly increasing throughout the world. It is generally recognized that natural products with a long history of safety can increase insulin sensitivity.

Aims: The present investigation examined the ability of various combinations of essential oils such as fenugreek, cinnamon, cumin, oregano, etc. to enhance insulin sensitivity. As a first approximation, we examined the effects of these natural products on Zucker fatty rats (ZFRs), a model of obesity and insulin resistance, and spontaneously hypertensive rats (SHRs), a model of genetic hypertension. Material and Methods: Water or essential oils were given orally via droplets, and insulin sensitivity was estimated by systolic blood pressure (SBP) changes and circulating glucose and/or insulin concentrations.

Results: We have found that the ability to alter SBP in rat models is the most sensitive early index of insulin sensitivity. The combined essential oils lowered circulating glucose levels and SBP in both ZFRs and SHRs, suggesting that these natural products are enhancing insulin sensitivity. The second series of studies examined two additional combinations of essential oils along with the original formula. The major differences were in the types and proportions of individual oils contributing to a given formula.

Conclusions: Although all the three formulae decreased SBP in ZFRs, one of the formulae was more effective than the others in lowering circulating glucose in the glucose tolerance testing. Accordingly, some essential oils may be added to the long list of natural products that can affect insulin sensitivity. Keywords: diabetes mellitus, essential oils, insulin resistance, insulin sensitivity, insulin sensitivity, natural products Received 11 August 2003; returned for revision 25 September 2003; revised version accepted 16 March 2004 Introduction The prevalence of insulin resistance and its most severe form type 2 diabetes mellitus is rapidly increasing in the USA – even throughout the world [1–3]. The recent increase is attributed, at least to some extent, to the greater occurrence of overweight and obesity that is due mainly to an augmented intake of calories and refined carbohydrates, lesser consumption of fibres and a more sedentary lifestyle [4–6]. Obviously, reversal of these situations should ameliorate the problem. Unfortunately, more is often needed than simply advising lifestyle changes that frequently fail in order to combat insulin resistance and its accompanying perturbations (cardiovascular diseases, obesity, dyslipidemias, diabetes mellitus and premature ageing) [7,8]. Experience shows that the afflicted not infrequently require aids to help with the maintenance of a healthful lifestyle. Correspondence: Harry G. Preuss, D, Georgetown University Medical Center, Department of Physiology and Biophysics, Basic Science Building, Room 231B, 4000 Reservoir Road, N.W., Washington, DC 20057, USA. O R I G I N A L ART I C L E doi: 10.1111/j.1463–1326.2004.00386.x # 2004 Blackwell Publishing Ltd Diabetes, Obesity and Metabolism, 7, 2005, 193–199 193

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    Acute administration of red yeast rice depletes tissue CoQ10
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    Date: May 13, 2005 03:00 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Acute administration of red yeast rice depletes tissue CoQ10

    Basically, if you are taking a Cholesterol lowering product that works on the same order as prescription drugs, you need to supplement CoQ10 to replace what the body is removing.

    British Journal of Nutrition (2005), 93, 131–135 DOI: 10.1079/BJN20041285 q The Authors 2004

    >

    Acute administration of red yeast rice (Monascus purpureus) depletes tissue coenzyme Q10 levels in ICR mice



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    TopPreviousNext

    Date: May 13, 2005 08:38 AM
    Author: Darrell Miller (dm@vitanetonline.com)

    Sulforaphane Stimulates the Body's Cancer-Fighting Enzymes

    Secret Weapon Against Cancer Found in Broccoli Sprouts

    by Richard Conant, L.Ac, C.N.

    The health benefits of vegetables were known historically, long before researchers began seeing a connection between vegetable consumption and cancer prevention. Over the last twenty years, evidence concerning this connection has steadily accumulated. The latest and most promising findings reveal that specific vegetable constituents—"phytochemicals" to use current scientific parlance— enhance the body's defenses against cancer.

    This article will focus on one phytochemical in particular, a sulfur-containing compound called "sulforaphane." Found in Cruciferous vegetables such as broccoli, sulforaphane may prove to be one of our most powerful cancer prevention allies. Recent studies have shown that sulforaphane stimulates, or "induces," "Phase two enzymes." These enzymes are an integral part of the body's elaborate detoxification system that renders carcinogens inactive. This detoxification system turns carcinogens and other toxic substances into harmless molecules that are excreted from the body.

    We need not fear carcinogens—the body is equipped to deal with them.

    These findings, coupled with an appreciation of the body's ability to defend itself against carcinogens, have the potential to dramatically change the way we look at cancer and substances in the environment that "cause" cancer. We need to minimize unnecessary exposure to carcinogens, and the staggering quantity of hazardous chemicals in the environment remains an urgent health concern, for cancer and many other health problems. But, knowing the body is equipped with the means to defend itself against toxins, we do not need to fear carcinogens as perhaps we have in the past.

    The natural world is full of carcinogens.

    What's more, even if you eat 100 percent organic food and live in a environment free of toxic man-made chemicals, you are still being exposed to carcinogens every day of your life. Food is the primary route of this exposure. Plants, for their own defense, produce over 99% of all the pesticides in agricultural products.1 Almost all foods—in their natural state—contain tiny amounts of naturally-occurring, potentially carcinogenic chemicals.

    The point is not to trivialize the concern over environmental toxins. The point is that the natural world is full of toxins that are not man-made. These substances have been around since before we appeared, which is why we have evolved with a highly efficient system for neutralizing them before they can damage our cells and initiate the complex process that produces cancer.

    Broccoli sprouts are a concentrated source of cancer-fighting sulforaphane.

    We cannot avoid carcinogens. What we can do is support our internal detoxification system. Sulforaphane is a powerful tool in this effort. We can start by following the often-repeated advice to eat a variety of vegetables every day, and include broccoli in our menu.

    There is an even richer source of sulforaphane than broccoli itself. In September 1997, a group of scientists at the Johns Hopkins University School of Medicine made a breakthrough discovery— broccoli sprouts contain ten to one hundred times more sulforaphane than mature broccoli.2 Vegetable sprouts are generally regarded as exceptionally healthy foods. Broccoli sprouts now look like a shining star, especially when it comes to cancer prevention.

    For those lacking the time or inclination to keep a fresh supply of broccoli sprouts on hand, broccoli spouts have been processed into an extract that is even more concentrated in sulforaphane. More on this later.

    What have researchers learned about broccoli consumption and cancer rates?

    More than 200 epidemiological studies—studies which track groups of people over time to uncover realtionships between variables such as diet and the incidence of disease—have invesitgated the connections between vegetable consumption and various forms of cancer.1 It should be understood that findings from epidemiological research are generally not regarded as conclusive; these studies are not controlled, and often use data gleaned from questionnaires, which are an imprecise method of gathering information. (In the case of diet questionnaires, for example, the study subjects may or may not record their food intakes with 100 percent accuracy.)

    Epidemiological studies look for trends. To be credible, these trends need to show up consistently, in different population groups. Findings from the vegetable intake/cancer studies easily meet these criteria; the number of studies is large and the trend is consistent—vegetable consumption is strongly associated with a lower risk of developing cancer.

    What about broccoli in particular? A paper published in the September 1996 issue of Cancer Epidemiology, Biomarkers & Prevention analyzes epidemiological data gathered from 94 studies concerning the cancer preventive effect of brassica vegetables.3 (The Brassica genus, part of the Cruciferae family, includes broccoli, cabbage, kale, cauliflower and brussels sprouts.) The data suggest that broccoli consumption reduces the risk of some of the most feared forms of cancer, including stomach and lung cancer.

    Now, to put these data into a balanced perspective, the researchers point out that in most of the studies reviewed, brassica vegetable consumption was reported as part of the total vegetable intake. "In hardly any epidemiological studies was the effect of brassica vegetables separated from the effect of total vegetables or other vegetables by adjusting for consumption of these variables. Therefore, it is difficult to sort out whether the observed observation was attributable to brassica vegetables, to vegetables as a whole, or to other vegetables," they noted.

    This uncertainty is a good example of why epidemiological studies alone do not give us open and shut conclusions. But the paper also adds that the apparent anti-cancer effect of brassica vegetables agrees with "the results of experimental studies in which brassica vegetables reduced mammary tumor incidence, hepatic tumor size, numbers of tumors per liver, tumor frequency, and the number of pulmonary metastases when given to rodents before or after a carcinogen insult."3

    When you put together a plausible trend from epidemiological research with results of experimental studies that agree with the trend, and then add additional research that reveals the underlying mechanism for these observations, a clear picture begins to take shape. And, indeed, we now have a fairly good idea as to just how brassica vegetables, especially broccoli, help prevent cancer.

    How sulforaphane helps prevent cancer from developing.

    To see how sulforaphane works, let's look at a brief overview of the body's detoxification system.

    The detoxification of carcinogens and other toxic substances takes place in the liver, and involves two distinct enzyme-driven processes or "phases". Phase one enzymes neutralize toxins by various routes. Some of these convert toxins into substances that are immediately eliminated. However, other Phase one steps convert toxins into intermediate products which are carcinogenic themselves, and require further treatment before they can be excreted. Phase two enzymes do this vital job. Phase two enzymes deactivate these carcinogenic metabolites of Phase one, and the final breakdown product is then eliminated once and for all. (For an excellent review of this subject, see Encyclopedia of Natural Medicine, by Drs. Michael Murray and Joseph Pizzorno.4)

    Phase two is critical. If Phase one is in good working order, but Phase two is not, the potential threat from carcinogens increases. It is vitally important to keep Phase two operating well. This is where sulforaphane plays its cancer preventive role. Sulforaphane is a powerful inducer of Phase two enzymes.5,6

    Broccoli sprouts-the ideal source of sulforaphane

    Sulforaphane is one among a group of phytochemicals called "isothiocyanates." (These occur in brassica vegetables largely as "glucosinolates," which are precursors for isothiocyanates2,12 When the plant is crushed, glucosinolates are converted to isothiocyanates.) Sulforaphane induces Phase two enzymes exclusively, leaving Phase one enzymes alone. This means it helps reduce the load of carcinogenic Phase one intermediates without adding to the load by stimulating Phase one.8,9

    As reported by the Johns Hopkins University research group, broccoli sprouts are an "exceptionally" rich source of sulforaphane (in the form of "glucoraphanin, sulforaphane's glucosinolate precursor). And broccoli sprouts have another advantage over mature broccoli. They contain almost no indole glucosinolates, phytochemicals present in mature broccoli that "can enhance tumorogenesis."2

    Broccoli sprouts as an extract, now available as a dietary supplement, takes the concentration of sulforaphane to the next level. This recently developed nutraceutical product contains a potent 20 to 1 extract of three-day old fresh broccoli sprouts.

    One 125 mg capsule supplies the same amount of sulforaphane as 125 grams, or about 5 ounces, of mature broccoli. Taking just one capsule a day is like eating two pounds of broccoli per week, which equals the intake of cruciferous vegetables believed necessary to obtain their health benefits.

    References

    1. Steinmetz, K.A. Potter, J.D. Vegetables, fruit, and cancer prevention: A review. J Am Diet Assoc. 1996;96:1027-1039.

    2. Fahey, J.W., Zhang, Y., Talalay, P. Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc. Natl. Acad. Sci. 1997; 94:10367-10372.

    3. Verhoeven, D.T.H., et. al. Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiology, Biomarkers & Prevention 1996;5:733-48.

    4. Murray, M. Pizzorno, J. Encyclopedia of Natural Medicine. Rocklin, CA: Prima Publishing;1998:110-120.

    5. Zhang, Y. Talalay, P, Cho, C., Posner, G.H. A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure. Proc. Natl. Acad. Sci. 1992;89:2399-2403.

    6. Gerhäuser, C. et. al. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. Cancer Research 1997;57:272-78.

    7. McDanell, R., McLean, A.E.M., Hanley, A.B., Heaney, R.K., Fenwick, G.R. Chemical and biological properties of indole glucosinolates (glucobrassicins): A review. Fd. Chem. Toxic. 1988;26(1):59-70.

    8. Talalay, P. Mechanisms of induction of enzymes that protect against chemical carcinogenesis. in Advances in Enzyme Regulation, Vol. 28, Weber, G., Ed., 1989: Pergamon Press.

    9. Prochaska, H.J. Santamaria, A.B., Talalay, P. Rapid detection of enzymes that protect against carcinogens. Proc. Natl. Acad. Sci. 1992;89:2394-98.

  • Broccoli Concentrate 850mg 60tb
  • Broccoli Seeds Sprt 4 oz.
  • Broccoli Sprouts 30tb
  • Broccoli Sprouts 60tb
  • Indol 3 Carbinol from Broccoli 30ct 100mg
  • Indol 3 Carbinol from Broccoli 30ct 25mg
  • Indole 3 Carbinol 200mg 30ct from broccoli


  • --
    VitaNet®
    VitaNet ® Staff

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=46)


    Long Jack PowerMax 200 from Action Labs
    TopPreviousNext

    Date: May 10, 2005 04:43 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Long Jack PowerMax 200 from Action Labs

    Hot from the Jungles of Asia

    Long Jack PowerMax 200

    The newest Performance product from Action Labs brand, Long Jack is a plant native to southeast Asia that has two folk names -- One is TongKat Ali, which means Ali's walking stick, and the other is Long Jack (Eurycoma Longifolia jack).

  • Research suggest that Long Jack may help to promote feelings of vigor and vitality while contributing to an over all sense of well-being.
  • Yohimbe Free!
  • 2 capsules supply 200mg of Tongkat Ali
  • 30 day supply
  • Long Jack PowerMax 200 60ct


    --
    VitaNet®
    VitaNet® staff

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=23)



    TopPreviousNext

    Date: May 09, 2005 11:35 AM
    Author: Darrell Miller (dm@vitanetonline.com)

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