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The Cannabis Remedy: Simple Solution For Over 40 Million PeopleSuffering With Anxiety
November 24, 2018 11:13 AM
Anxiety is a very prevalent condition, both in the U.S. and worldwide. In fact the National Institutes of Health concur that as much as 33% of the world's population has suffered, or well suffer from some type of anxiety. Besides mentally specific symptoms, such as worry, fretting, inability to focus, nervousness and fearfulness, the condition can create physical symptoms as well, such as clenching, sweating, dizziness, accelerated breathing, pulse and raised blood pressure. At it's worst, anxiety can induce a full-blown panic attack, depersonalization and even a certainty that one is dying. Obviously anxiety is a potentially critical condition, with the ability to disrupt life, even in small ways. As it worsens, anxiety can make it difficult to impossible for sufferers to work or socialize effectively. Though triggers vary, most people are visited by anxiety due to one of three big concerns, namely fears that center around finances, safety, or health. One poll conducted by the American Psychiatric Association concluded that keeping the family safe and bill-paying were huge anxiety triggers that resonated with more than 60% of respondents. The positive news is that many people can experience mitigation, if not complete surcease of these symptoms by using cannabis, which is expected to keep growing as an industry. THC which is the psychoactive component in cannabis, that which makes it illegal if it gets past .3%, is minimal to almost nil in hemp, which is related to, but not the same as marijuana. The THC amount will vary in cannabis products. There is hemp oil, hemp seed oil and CBD oil, which is made from the entire plant, flowers and all, so it may have a bit more THC. Oil products can be taken topically, or sublingually, even smoked. By acting on receptors in the central nervous symptom, the constituents of the oil act to mitigate the symptoms of anxiety. Even beyond pain relief these products have been shown to have efficacy for symptoms of epilepsy, pain and impaired cognition.
"The good news is, there are ways to cope, even ways to alleviate anxiety and its symptoms using natural and drug-free solutions."
Read more: https://www.thealternativedaily.com/cannabis-remedy-solution-people-suffering-with-anxiety/
Fight menopausal symptoms with fermented red clover extract
October 14, 2018 01:38 PM
According to a recent Danish study, fermented red clover is an herbaceous plant that can effectively be used to treat mood swings and hot flashes associated with menopause. Furthermore, the red clover extract can help to prevent osteoporosis that may occur for some menopausal women. Researcher Dr. Lambert claims that the key to the beneficial properties of red clover extract is the fact that it’s fermented, which helps support the bioavailability of the plant’s estrogen-like compounds, otherwise known as isoflavones. This research on fermented red clover is important given that the unpleasant symptoms of menopause affect one in three women over age 50.
"The fermented extract is a remedy of great efficacy. In addition, the extract prevents osteoporosis or bone loss that is accelerated by menopause, which affects one in three women over the age of 50."
Read more: https://www.naturalnews.com/2018-09-24-fight-menopausal-symptoms-with-fermented-red-clover-extract.html
To Get Rid Of Inflammation, Avoid These 5 Foods Like The Plague
May 02, 2018 09:17 AM
Inflammation in the joints can cause tremendous pain that you certainly do not want to experience. Shockingly, it could be the foods that you are eating that is causing you to experience inflamed joints. What foods are on that list of foods to avoid at all costs? There are several that you should not eat if inflammation is of concern, but the five hee are among the worst that you should ensure yu avoid at all costs.
"You’ve no doubt heard about the growing gluten-free craze that’s sweeping the nation, and you probably have some idea that gluten is bad news for most people."
Read more: https://www.thealternativedaily.com/these-5-foods-direcly-cause-inflammation/
Could Diet Sodas Raise Risk of Dementia and Stroke?
April 27, 2017 10:44 AM
Diet sodas are not a healthy choice for those dieting. New studies have shown that people who drink them are not experiencing health benefits and are at a three times higher risk of experiencing dementia and stroke. The study did not discern which artificial sweeteners were consumed. People that drink sugary beverages did not have the same risk factors but those who drank sugary risks had a higher risk of memory loss and accelerated brain aging. Experts agree drinking water and coffee are healthier alternatives.
Read more: Could Diet Sodas Raise Risk of Dementia and Stroke?
Is the water you're drinking linked to causing heart attacks and cancer?
February 28, 2017 12:59 PM
Water chlorination has been the cheapest method of disinfection for over a century. Chlorine efficiently disinfects large quantities of water. It is generally used to prevent outbreaks such as salmonella, and can even inactivate the human norovirus. For these reasons, the EPA classifies chlorine as a pesticide. Even though chlorine is an effective pesticide, on a grand scale, it is hard to measure how quickly microorganisms learn to evolve and resist the persistent use of this chemical. Could widespread dependence on chlorine contribute to accelerated microbial resistance?
"Could widespread dependence on chlorine contribute to accelerated microbial resistance?"
10 health concerns you can detect through your eyes
November 26, 2016 06:59 AM
While I was driving the car in the city where traffic was bad, I found the brake override warning lamp illuminated on the combination meter sometimes. And then, when I accelerated the car while the light was illuminated, unexpectedly the engine did not have power.
"When you meet someone new, the first thing you notice about them is probably their eyes—the shape, the color and sometimes their health"
What Is GMO and Why Should We Avoid It?
June 21, 2014 02:40 AM
Cause of GMO
GMO's have been classified by the American Academy of Environmental Medicine as unhealthy, they were able to prove that GMO when ingested can cause organ damage, gastrointestinal as well as immune system disorders. This is due to the fact that GMO contains materials that are left behind the body, it can cause long term problems like accelerated aging as well as infertility. The genes inserted into a genetically modified crop like corn, can get transferred into the DNA of bacteria that is living inside the human body, this interaction can lead to a number of long term health problems.
Negative effects of genetically modified products have been observed in 1996, this was due to the number of Americans expressing a number of illnesses after consuming foods that have been engineered for 9 years.
Allergies increased including digestive problems and autism, while other research has yet to support this claim, many non-profit organizations such as Greenpeace are already making campaigns against the production of GMO infused crops and meat.
What are the other negative impacts of GMO?
1. Cancer causing components - GMO according to the American Public Health Association and American Nurses Association, have stated that the growth hormone present from cow’s milk treated by hormone IGF-1 can lead to cancer.
2. Long term negative effects on the body - GMO components can contaminate forever, it can cross pollinate, and the seeds can travel. Once it infects a certain area, it can contaminate the entire gene pool. This means, that the health of future generations is already compromised and for this reason, the production has to be stopped right away before it infects more population.
3. Dangerous side effects - the mere process of creation of GMO's can produce toxins, carcinogens, allergens and nutritional deficiencies.
The direct production and consumption is already endangering a number of species including bees.
Many governments continue to remain lax about the issue, GMOs are illegally being sold and created in many countries, and people need to learn as much as they can in order to learn how they can prevent GMO products from entering their market.
Arginine and Ornithine Supplementation for Enhanced Athletic Performance
January 19, 2014 07:41 AM
Arginine and ornithine
Arginine and ornithine are two amino acids that are incorporated in protein that is found in many dietary sources, such as meat, egg whites, soy or fish. Although these two amino acids can be supplied to your muscles from food sources, several research studies have examined the benefits of arginine and ornithine supplements. Fitness researchers found positive and promising results in terms of muscular growth, endurance and fatigue prevention. These supplements are especially known and popular among bodybuilders and other types of strength athletes, as it has been clearly demonstrated that they improve athletic ability on a biochemical level.
What Is The Difference Between DGL Licorice and Regular Licorice?
February 13, 2012 07:35 AM
Manypeople these days have heard of the name “Licorice” because of the various chewy rope-like flavored confectionaries or candies that are widely available these days and taste amazingly sweet. However, most of these people have never paid attention to what these candies are made of. The fact is that these candies contain the extract from Licorice roots. The Licorice roots are yielded from the Licorice or the Glycyrrhiza glabra plant. The extract from these roots has been used from quite a long time, both as a food ingredient and as an herbal remedy.
However, the Licorice root also has a derivative form known as deglycyrrhizinated or DGL Licorice. Both of these products offer numerous benefits and when taken under medical supervision they can effectively help in treating a variety of medical ailments.
Licorice plants originate from the Middle East, where harvesters peel the root out of the plant, dry them, cut them and eventually the Licorice roots arrive in other countries. Glycyrrhetic acid, cumestan derivatives, hydroxycoumarins, isoflavonoids, triterpene saponins, etc. are some of the active constituents contained in regular Licorice roots. One problem with using Licorice roots was that it was generally recommended that people use the extract from the root only under medical supervision. This was mostly because of the Glycyrrhetic acid contained in the root.
Thus, while DGL Licorice is indeed derived from Licorice root, however, glycyrrhetic acid is removed during the preparation of DGL. Therefore, this form of Licorice can be consumed much more safely without any worries. Furthermore, ulcers the esophagus, in the mouth and the stomach lining in the small intestine are more effectively treated with this derivative form of Licorice. DGL Licorice is presently widely available as chewable tablets, mouthwashes and even teas; therefore, people have a few choices as to how they want to take the derivative extract that comes from the root of the Licorice herb.
DGL is actually an effective treatment for digestive problems like heartburn and GERD or gastroesophageal reflux disease, ulcer, etc. What makes this derivative extract so beneficial is that the protective factors of the digestive system are accelerated and/or stimulated by its mechanism as a result of which the internal lining of the intestines in the stomach are protected against the formation of ulcer. Unlike typical antacids and anti-inflammatory drugs that basically neutralize or suppress gastric acid, the DGL extract functions quite differently.
Apart from helping treat the mentioned digestive problems, even minor skin conditions such as carbuncles, eczema, minor cuts and wounds can also be effectively treated by applying ointments that contain DGL. Apart from being better than the regular extract obtained from the Licorice root, the DGL derivative is also far more effective anti-ulcer compound in comparison to the typical medications that are available these days. It is usually advised that DGL should be taken at least twenty minutes before meals. And usually 2 to 4, 400 mg tablets are the standard dose of DGL that can be taken for chronic cases of ulcer. Therefore, those who are considering using Licorice root extract should instead go for DGL Licorice.
Bioperine Promotes Maximum Absorption
February 06, 2012 06:19 PM
Bioperine is an extract from black pepper that contains about 95 percent piperine. Piperine is an alkaloid, the active substance that contributes to nutrients bioavailability and absorption. Bioperine can be combined with other specific nutrients to form different nutritional supplements that can be used for both animal and human consumption. Black pepper is mostly harvested before ripening, dried in the sun and then the extraction process begins.
How and why use of Bioperine promotes maximum vitamin absorption
Recent research has shown that the use of Bioperine, whose main constituent is piperine, increases thermogenic activity in the body. Thermogenesis is an accelerated metabolic process that takes place in the body cells in which conversion of glucose into energy takes place. An increase in absorption of discount minerals such as selenium and vitamins such as vitamin A has been witnessed to be triggered by the use of Bioperine. Piperine works through initiating the release of catecholamines hormones that stimulate thermogenesis. However, the nutrients should presently available during this time since; the process takes place for a short duration.
Piperine improves the necessary conditions of the intestines thus enhancing vitamins absorption. It alters the intestinal epithelial cell wall making it more permeable to vitamins and minerals. In addition, absorption of protein supplements such as those used by people who are on a dietary weight loss program is also increased. Several researchers have also shown that Bioperine has other benefits in the body, these includes the antibacterial properties and anti allergy properties.
Experiments prove that use of Bioperine increases vitamin and mineral absorption
Several studies on how much piperine promotes nutrients absorption have been carried out hitherto. For instance, an experiment was carried out on the effect of absorption of beta-carotene, vitamin B-6 and selenium which are fat soluble vitamin, water soluble vitamin and mineral in the form of selenomethionine respectively in the presence and absence of piperine. The experiment showed that absorption of these vitamins and mineral selenium increased appreciably when taken with Bioperine. There was 60 percent increase in absorption of beta-carotene and vitamin B-6 while 30 percent absorption was noticed for selenium. The experiment was carried out using 5 milligrams of Bioperine. Another experiment also showed a 30 to 200 percent increase in the absorption of Coenzyme Q-10.
Bioperine is the only piperine product to undergo comprehensive health tests and to be patented for the effect of increasing nutrients absorption, more so vitamins and minerals. By creating metabolic changes that require vitamins and minerals, Bioperine creates a nutritional need and then follows by increasing the nutrients bioavailability to meet the need. However, the process takes place in a short period. It is therefore advisable to co-administer minerals and vitamins with Bioperine so that they will be available during the right time for absorption. Unfortunately, research has shown that taking black pepper in its natural form does not yield the same results as those of taking Bioperine. This is mainly because the bioavailability of piperine is not that high in the natural form. Finally, antibacterial and anti allergy properties of Bioperine diversifies its application in medication.
Hyaluronic acid and your cells, eyes, and skin
December 17, 2010 10:48 AM
Discovered in 1934, hyaluronic acid can be found anywhere there is the need for connective tissue in your body. Your joints, your eyes and your heart all contain hyaluronic acid, and a shortage can lead to a wide range of bodily defects, including the appearance of accelerated aging. It is a glycosaminoglycan, a form of polysaccharide that is not only found in connective tissue and epithelial and neural cells, but is also important in the growth and renewal of body cells.
We shall discuss here how hyaluronic acid affects specific areas of your body, and what the effect of a deficiency would mean, but also keeping in mind that an excess of this polysaccharide can also have a serious impact on your health although it offers few side effects worth noting.
Hyaluronic Acid and Your Joints
The highest concentrations of hyaluronic acid (HA) in your body is found in the synovial fluid, the fluid lubricating contained in your joints, and it is also plays an important role in maintaining the function of cartilage in keeping your joints flexible and well cushioned. It is chemically a glycosaminoglycan that is formed from glucosamine and glucuronic acid. Its production is boosted by chondroitin, which is why glucosamine and chondroitin are commonly used supplements for the treatment of arthritis.
Specifically, HA joins with collagen and elastin to produce cartilage, and also increases the supply of synovial fluid that maintains lubricity within the joints. Without the synovial fluid your cartilage would soon become worn away and your bones would grind together, eventually seizing up. By taking hyaluronic acid orally as a supplement, you can help to maintain healthy joints by maintaining the integrity of the cartilage and the quality of the synovial fluid.
Because the cartilage contains no blood vessels, it is reliant on the synovial fluid to keep it supplied with nutrients, and specifically with HA which is a large part of its structure. Without this important polysaccharide your body would not be able to function: no mobility, dry flaky skin and poor or no eyesight.
Hyaluronic Acid and Your Skin
Hyaluronic acid occurs in the lower layers of your skin where it helps to maintain a smooth and full appearance to your skin due to its hygroscopic nature in absorbing up to a thousand times its weight of water. For this reason HA is frequently used in skin moisturizing treatments and lotions.
HA is not found inside body cells, but appears to be restricted to the extracellular regions between cells where its moisturizing properties are critical in maintaining suppleness. Elastin requires copious quantities of water to remain elastic or it would otherwise become brittle: that is why our skin looks dry and wrinkled when we age. It is due to a lack of moisture: the moisture that hyaluronic acid can bring to the table. The problem is that HA reduces with age and in order to maintain our youthful looks we have to take a supplement.
Hyaluronic acid doesn't last long in your skin: it has to be renewed constantly and each day about 50% of the HA content of your skin is lost. It takes about two weeks for the same degree of loss to occur in the synovial fluid of your joints. The look of your skin depends to a very large extent on the extracellular matrix, or what is contained between your skin cells. The more moisture there then the smoother and plumper your skin will appear.
As you age, your hyaluronic acid production drops and so your skin becomes increasingly more depleted of moisture. This causes it to dry up and wrinkle. Were there one substance that I would choose as the elixir of life it would be HA, because by taking a regular supplement your natural daily loss is replenished and your skin is given a hand to maintain its soft, moist plumpish look that helps you to keep you looking young.
Hyaluronic Acid and Your Eyes
The vitreous humor is the liquid inside your eyeball, and it contains a large amount of hyaluronic acid. It helps absorb shock and to maintain the shape of the eyeball. The HA is so important that your body has developed a special set of cells known as the hyalocytes of Balazs that are believed to promote the renewal of hyaluronic acid, and also possibly its breakdown.
There is still a lot of research going on into this but the importance of HA in the vitreous humor and other aqueous area of your body is not in question. It helps to retain water and give structure to the liquid media within your body, whether that is between the bones of your joints, in the dermal and epidermal regions of your skin to keep it supple, or in your eyeball. In fact, it is believed to take up 70% - 80% of your eye, and helps to keep the retina in place exactly where it has to be for your eyesight to work.
Because Hyaluronic acid is:
a) present between the cells in every tissues in your body, and
b) a consumable, in that it gets used up rapidly, and
c) your biochemistry's ability to regenerate it reduces with age,
a supplement is the ideal way in which to maintain its levels in your extracellular system. In some instances injections are given, particularly in expensive anti-wrinkling treatment, but studies have shown that hyaluronic acid baxyl taken as an oral supplement shows an improvement after an average of 3 months treatment.
It should be understood that the average person has around 15 grams hyaluronic acid in their body, of which 5 grams is continually degraded and synthesized daily. When you reach an age that your ability to generate HA is impaired, then an oral supplement will be less expensive than injections, the hyaluronic acid of which will also be degraded with time. It won't be long before you need more treatment, and oral supplements are less expensive than private hypodermic injections.
A Hyaluronic acid supplement baxyl can be taken to improve the suppleness and appearance of youthful skin, help maintain the integrity of your eyesight and help to reduce the symptoms of arthritis and many other conditions brought on by a reduction in the synovial fluid and hydration of the skeletal and connective tissues of your body. In other words, it helps to keep you looking younger for longer and to keep your joints and your eyesight in good health.
Have you had your daily dose of hyaluronic acid today?
Baxyl is a liquid form of hyaluronic acid that is easy to take and easily assimilated into the body because its a liquid.
Fight Anxiety Disorders Naturally
December 14, 2010 04:27 PM
Do you suffer from an Anxiety Disorder?
Before considering how to test for anxiety disorders and discussing natural supplements that can help we should first discuss what anxiety disorders are - what the term means and if there are degrees of anxiety disorders as there are of depression and stress. First, what is anxiety?
Anxiety is a natural reaction to stress and it is anxiety that makes you worry about the consequences of not studying for an exam - so you study. It focuses you on problems so that you will be more likely to solve them, and helps you to perform better whatever you are doing. However, it can get out of hand and these positive mental processes become negative anxiety disorders.
With some people, anxiety becomes a dread of situations that were once everyday occurrences and can make your life a misery. Here are some forms of anxiety disorder.
Typical Anxiety Disorders
General Anxiety Disorder
Its symptoms include excessive sweating, worry, headaches, irritability, difficulty in sleeping, tiredness and tension in your muscles. It can lead to substance abuse and deep depression if left untreated.
These are three typical forms of anxiety, but how do you test for anxieties? Here are some tests that are used, beginning with the easiest - doing it yourself!
Testing for Anxiety Disorders
Many that believe they may have an anxiety disorder either tend to panic or go into a depression. It is far better to carry out a self-test. This anxiety test is very simple: simply tick which of the symptoms below you have experienced in the past six months:
I can't relax
I am always worried about something.
I get headaches for no apparent reason
I frequently sweat a lot and get hot flashes
I have no time for anybody and am easily annoyed
I find it hard to sleep and I often wake up during the night
My attention keeps wandering and I can't focus on anything
I sometimes get so worried I want to be sick or have a lump in my throat
If you have ticked more than three then perhaps you should pay your doctor a visit, or try some of the recommendations below.
b) Doctors' Tests
If you feel you might be suffering some form of anxiety disorder you should consult your doctor, particularly if you have tried the self test above and it indicates that you might be. Your doctor might carry out various tests for your general health, and if it is felt necessary you may be asked about your family history: is there any history of mental problems in the family, particularly with your mother or father.
Other questions may appertain to your own physical and mental background, such as have you been stressed for any reason lately, have you suffered anxiety or panic attacks in the past and what is your normal use of prescription and non-prescription medications and drugs. Do you smoke, drink or take any social drugs.
It is important that you are totally honest: the doctor is not judging you, simply trying to find the cause of your problem. Under the terms of their oath they cannot divulge anything you tell them to anyone else, so be honest and let them help you. Among the tests you will be given will be to declare all your history of anxiety-related symptoms. To achieve that, you will be asked a series of questions while the doctor assesses your mental condition.
Finally, you may be referred to a psychiatrist who will be able to help you more than your doctor. Psychiatrists have a good record in resolving anxiety disorders, but once you are diagnosed positively, what then? Chemical drugs? Or perhaps you would prefer something more natural such as herbal remedies.
Herbal Remedies for Anxiety
There are a number of herbs that can be used to treat anxiety disorders. Here are the more commonly used of these:
Passion flower contains the active substances maltol and ethylmaltol that your body's biochemistry uses to increase the concentration of GABA (gamma-butyric acid) in your brain. GABA is a neurotransmitter that calms you and helps you to relax and forget anything that is making you anxious. It relieves muscle tension, can lower your blood pressure and some equate its effect to that of Valium: although it is totally different chemically it is similar in its effect. It offers a sedative effect and helps you sleep.
Kava Kava root
Kava kava. Generally just referred to as kava, comes from the Pacific and the kavalactones it contains increase the concentration of neurotransmitters in your vascular system, particularly serotonin, the feel-good substance. Its sedative effects have been likened to that of alcohol, and it can certainly give you a lift and certainly helps you worry less as it reduces the negative symptoms of stress and depression.
St. John's Wort
St. John's wort is a well-known anti-depressant and it can also help reduce the symptom of anxiety. The hyperforin the plant contains helps to improve the brain's content of the neurotransmitters serotonin, dopamine and norepinephrine that make you feel good, and St. John's wort certainly washes away your anxiety. Not only that, but the napththodianthrone in another of its important components, hypericin, promotes a reduction in depression through the inhibition of monoamine oxidase, a pro-depressive enzyme.
An extract of valerian root can help you to relax and sleep well, and this can often be enough to prevent your anxiety attacks. A lot depends on their cause, but if the attacks are mild and don't require extensive medical or psychiatric intervention, then valerian can help, particularly in treating stress-related anxiety. Make sure you stick to the recommended dose because valerian can be dangerous if taken to excess.
The four herbal remedies above should between them be all you need to treat your anxiety. One major problem is that, just like any chemical drugs, they only treat the symptoms and not the underlying cause which is something you and your physician will have to work on yourselves.
However, until then, the above herbal remedies for anxiety disorders are generally safer to use than prescription drugs and each has a well proven effect, both on the symptoms of anxiety and on depression.
Build Healthy Bones With A Good Bone Builder Supplement
May 22, 2010 12:17 PM
Since bones are living tissue, healthy bones need at least 24 bone-building materials in order to be at their best. These materials include both trace elements and protein. The most important minerals to bone health are calcium, magnesium, phosphorus, and potassium. The balance between these minerals is just as important as well. Strong bones need a lot of calcium, but calcium supplementation must include the presence of magnesium, as it increases the retention of calcium within the bone. Phosphorus is another important component in bone formation, as it must be in proper balance with calcium. If you take too much of it, which can be gained through soft-drink consumption or high protein intake, it will suck the calcium out of the bone, therefore, weakening the bone’s integrity. Vitamins D and K are also essential for increased calcium deposition.
Silicon, boron, and zinc are also required in order to strengthen the bone’s mineral matrix. Vitamin C stimulates the formation of the collagen matrix, which is an extremely important protein component that creates a structure for calcium crystallization. Silicon increases the bone-mineral density. Additionally, it seems to have a role in the prevention and treatment of osteoporosis. Silicon deposition is found in areas of the body that experience active bone growth. Because of this, it is suggested that this mineral may be involved in the growth of bone crystals as well as the process of bone mineralization. Zinc is also important for the proper action of vitamin D, as its status plays a huge role in bone health. When an increase in zinc excretion takes place, accelerated depletion of bone-mineral content also results. This situation is very common among osteoporosis sufferers. Diets that are low in zinc have also been shown to slow adolescent bone growth as well.
Lastly, vitamins B6, B12, and folic acid are necessary for reducing mineral loss as they modulate blood homocysteine levels. Vitamin B6 is a water-soluble vitamin used in the metabolism of amino acids. Vitamin B12 is one of eight B vitamins which is crucial for the normal functioning of the brain and nervous system, as well as the formation of blood. It is normally involved in the metabolism of every cell of the body. It affects DNA synthesis and regulation as well as fatty acid synthesis and energy production. Folic acid is a form of the water-soluble vitamin B9. It occurs naturally in food and can also be taken as a supplement.
The scientific evidence that has been found has supported the need for long-term supplementation with several key nutrients in order to maintain bone health. This is especially true for those women who are in their peri- and post-menopause years. Supplementation with vitamins D, K, C, B6, B12, folic acid, as well as the minerals boron, calcium, magnesium, silicon, and zinc at levels that are declared to be suitable for optimal nutrition health by nutritional authorities is an important component of product-rating criteria. Researchers question whether each product contains vitamin D, vitamin K, vitamin C, vitamin B6, vitamin B12, folic acid, boron, calcium, magnesium, silicon, and zinc at potencies that are up to 100% of the potencies for these nutrients that are stated in the Blended Standard.
Look to your local or internet vitamin store for bone building formulas that contain all these essential vitamins to help the body support a healthy bone structure. Remember to always choose name brands like Eithical nutrients and Solaray to ensure you buy a high quality complete bone building supplement.
L-Arginine An Amino Acid Essential Or Not You Be The Judge?
January 06, 2009 04:01 PM
L-Arginine is an amino acid that is one of 20 needed by the body for its existence. To some, it is not what is known as an essential amino acid, since it can be biosynthesized by the body, but arginine is termed a conditionally essential amino acid in that we must include some in our diet because our biochemistry does not produce all that our body needs, particularly during the growing years.
Amino acids are the building blocks of life, and are the units from which proteins and ultimately our DNA are built. In fact DNA contains the blueprints for every protein used by our bodies, including all the enzymes without which our biochemistry could not occur. When a supply of a particular protein is needed, the DNA template provides the sequence of amino acids needed to produce it.
Of the 20 amino acids we need, only 10 can be produced by our body: the other 10 must be included in our diet and are termed 'essential' because they are an essential part of our diet, just as vitamins and minerals are. Without an adequate supply of essential components, we cannot survive, and if the essential amino acids are depleted in our diet then the body will break down muscle tissue to release them.
Although L-arginine is termed a 'conditionally' essential amino acid, it is included by many among the 10 regarded as being essential. Hence, depending upon who you read, it can be either essential or non-essential. That is because, as inferred earlier, arginine is needed for growth and development, and there is insufficient in the diet to meet these needs. Therefore, while it is essential in cases where growth is still taking place, it is not in those where normal growth is complete.
Proteins are essential for all animal life, forming not only the enzymes, or biochemical catalysts, but also muscles and DNA among other bodily tissues. Protein is also a necessary part of our diet, and it is from protein, animal or vegetable, that we get the amino acids in our diet. L-arginine is one of these, being available from all meats and seafood’s, and vegetables rich in protein such as soy, seeds, nuts and grains.
So what does arginine do for us, quite a lot in fact, many of its functions being related to our health? Arginine plays an important role in the healing of wounds, especially bone, assisting the immune function, decreasing blood pressure and speeding up the repair time of tissue. However, it possesses other properties such as increasing muscle mass, helping to increase male fertility and improving the circulation.
It also helps to remove ammonia from the body, and is a precursor for the biosynthesis of nitric oxide (NO2). It is in the way that L-arginine works with the nitrogen stores of the body that we will focus on here, prior to touching on its other properties.
L-Arginine transports, stores and excretes nitrogen, and used biochemically to manufacture nitric oxide. This oxide of nitrogen plays a very important role in your body, and is produced in every cell of your body. Nitric oxide helps in the dilation of your blood vessels, allowing a reduction in blood pressure, better circulation and helping to prevent a mans man-hood dysfunction, all of which are due to its relaxing effect on smooth muscle contraction and the promotion of the increased blood flow necessary for men and their functions. It is also important to your immune system and nervous system.
It works in a similar way to the effect of nitroglycerine on the heart: this is converted in the body to nitric oxide which relaxes the blood vessels and so reduces the amount of work needed by the heart. The way in which L-arginine forms nitric oxide is by the action of the enzyme nitric oxide synthase.
The amino acid is also an important component of the Citric Acid or Kreb's cycle, where it reacts with ammonia which is a toxic by-product in the generation of energy in the mitochondria. Ammonia is converted to urea by L-arginine and excreted from the body. This is another way in which L-arginine is involved in the storage and use of nitrogen-containing compounds in your biochemistry.
It was mentioned earlier that arginine is an essential amino acid for children. Studies have indicated that it supports the release of the human growth hormone from the pituitary gland although the amount released through supplementation of the amino acid varies widely between individuals. The growth hormone maintains the production of proteins and muscle tissue in the body cells. This reduces as we age, and arginine becomes non-essential, the smaller amounts needed in our biochemistry being manufactured by the body.
The anabolic effect of the supplement is believed to increase the effectiveness of exercise intended to increase muscle bulk and reduce the percentage of body fat, and many take L-arginine as a supplement while undergoing such anabolic fitness and exercise programs. It is normally best to start with low supplement levels and work up due the potential side effects (diarrhea and nausea).
Arginine is an important component in the body's healing mechanisms for both tissue and bone, and studies have confirmed accelerated healing of wounds and fractures with arginine supplementation. Although the mechanism by which this occurs is not yet understood, there is evidence that it may be connected with the nitric oxide pathway and increased blood flow, and also with its effect on the immune system in reducing inflammation at the healing site.
Diabetics, however, should be careful with substances that promote the release of growth hormone, and children with incomplete bone growth should also use such agents only under medical supervision. With diabetics, their condition could be either exacerbated or improved, and those with herpes and some psychotic conditions should also be careful.
Nitrogenous compounds are essential to life, and L-arginine plays a significant role in the storage, use and secretion of them. Without it life would not be possible, although it is its visible uses, such as the effect of nitrous oxide on blood flow and of proteins on muscle metabolism, for which it is best known to those that use it, either as a supplement or as a remedy. Pure supplement form is available at your local or internet health food store.
November 12, 2008 09:51 AM
Gymnema sylvestre is found naturally in central and southern India, where it has been used in traditional Indian medicine for almost two thousand years. It is known as 'gurmar' in ancient Indian texts, a word meaning 'sugar destroyer', which gives an indication of its uses in medicine.
It is used to reduce the absorption of glucose into the body, and also reduce the sweetness of foods, both of which are desirable for those wishing to lose weight and to reduce the level of sugar in their blood. It was used for this purpose in Ayurvedic medicine, subjects being given the leaves to chew. As with many other ancient Ayurvedic remedies, this use of gymnema sylvestre has passed into modern times, and has sound scientific basis. First, however a bit more about the plant itself.
It is found predominantly in the Western Ghats, and also to the west of the mountains, around coastal Goa. It is a vinous plant that climbs on other bushes and trees, known in Sanskrit as Meshasringa, or ram's horn after the shape of the leaves from which the supplement is extracted. For what it's worth, the official name seems a mix of Greek and Latin (gymnos(Gr) - naked and Silva (L)- forest) for naked forest. That, however, is irrelevant to its uses, so let's have a look at the science involved and the active ingredients in the plant.
The main constituents are terpenoid saponins known as gymnemic acids, so one can assume that they were first found in this plant. They are glycosides, including hodulcine and ziziphin, which act as sweetness inhibitors so that there is no sweet taste in anything that is sweetened by sucrose. There are over 20 types of gymnemic acid in the leaves, of which the strongest, Gymnemic Acid 1, can suppress the sweetness even of artificial sweeteners such as aspartame.
These are not irreversible effects, and last only about 10 minutes, after which normal sweetness is detectable by your tongue. During the active period, however, a solution of normal sugar will taste like ordinary unsweetened water. However, is this just a matter of taste, or does it affect the sugar itself?
Studies have shown that animals fed the leaves of Gymnema sylvestre develop hypoglycemia, probably because it stimulates the pancreas to generate insulin that reduces the level of sugar in the blood. Further studies have shown the presence in the leaves of a number of types of acylated derivatives of deacylgymnemic acid. There are well over a dozen types of saponins known to be contained within the leaves.
Other chemicals found include anthraquinones, flavanoids, chlorophylls, querticol, phytin, a number of glycosides and anthraquinones. The bush also contains alkaloids, although these are constituents in most plants used in ancient remedies. This is by no means all of the chemicals discovered, and many of the minor benefits of using it could be due to the minor constituents of this amazing little leaf.
A study of the above constituents will reveal a few antioxidants, and it is no surprise that the extract from Gymnema sylvestre also possesses anti-inflammatory properties. Gymnemic acid is believed to have a similar chemical structure to saccharose, and the plant extracts can be used not only to reduce a craving for sugar, but also to treat digestive problems and high cholesterol levels. So what scientific evidence is there other than the obvious effects reported by those that use it?
A study in the UK in 2005 found that an aqueous extract of Gymnema sylvestre caused the secretion of calcium and insulin from mouse and human cells to be increased at a specific concentration without affecting the cellular function. This means that the supplement can be used to stimulate the secretion of insulin with people with Type 2 diabetes without otherwise affecting health. Its usefulness to diabetics is obvious, but there are other health benefits to those that are not diabetic.
Anything that modulates a sweet tooth must be of use to those seeking to lose weight, particularly if they feel the need for sweet foods. In fact Gymnema tends to reduce food cravings for carbohydrates and sweets, and can be used by those seeking a natural means of curbing their appetite for sweet and sugary foods. Because excess weight can lead to diabetes,
Although there have been many discussions about the biochemical mechanism of the gymnemic acids in this effect on taste, recent evidence suggests that the phytochemicals act on both your taste buds and on those parts of the intestine responsible for absorbing nutrients from digested foods.
Not only that, but studies have also indicated that Gymnema sylvestre removes the bitterness of acerbic chemicals such as quinine in the same way that it removes the sweetness form cakes and candies, and if you drank tonic water it would taste just like water. On the other hand, if you ate an orange, you would taste the acidity but not the sweetness.
The way to use this remarkable supplement is to follow the instructions, and within about a week you will be able to control your appetite much better, and any cravings for carbohydrates you previously had will be much reduced. After a month or so, you will notice an accelerated rate of weight loss if you had been overweight, and diabetics will find a significant reduction on blood sugar between insulin shots.
Gymnema sylvestre can take care of any sugar or carbohydrate cravings, and is of significant use to the overweight, obese or to diabetics, and the mechanism by which it works has now been all but understood, although there are still some biochemical secrets that this amazing plant has yet to reveal. This amazing herb can be found at your local or internet vitamin store.
November 10, 2008 10:30 AM
Guggul is a natural herb supplement that may help lower cholesterol, yet few in the Western hemisphere know much about it. Guggul is otherwise known as the Mukul myrrh tree, and is a plant of the Burseracae family with small red or pink flowers.
It is found across central Asia over to North Africa, although is very common in the northern areas of India where the climate is more semi-arid than equatorial. Guggul does not like a lot of water and can thrive in ground where the soil has few nutrients. Its Latin name is Commiphora wightii, and it grows about 12 feet high.
It has been predominantly used in the Ayurvedic medicine of ancient India, and like many such ancient remedies and treatments, is now used in modern medicine to treat specific conditions: conditions such as some forms of heart condition, where it has been found to be able to lower your blood cholesterol levels, weight loss and some forms of arthritis and other inflammatory conditions.
However, it has been used so successfully over the years, particularly in India, which it is now in danger of extinction and is contained in the Red Data List of the World Conservation Union that lists endangered species. So what is so special about this plant that makes it so popular? To get the answer to that we have to go back a bit in its history, although not quite as far as the two or three thousand years that it is known to have been used in traditional Hindu medicine.
The active ingredient is found in the sap of the tree, and is used to fight against obesity and other diseases that can be caused by excess weight or cholesterol, such as arthritis, obesity and atherosclerosis. Until recently it has had very little support for its claims from conventional medicine. It was in the 1960s that an ancient Sanskrit text was found that recommended guggul as a treatment for high cholesterol levels. Since that discovery, research has focused on the plant's anti-cholesterol properties, and a great deal of evidence has been gathered supporting the claims of that ancient text.
So much so that the Indian government has approved the use of guggul for the treatment of high cholesterol levels, largely because it has been found very effective in reducing the levels of 'bad' LDL cholesterol in the blood while increasing the levels of the beneficial HDL cholesterol. Several trials have supported this, including one study involving 228 patients that showed the extract to be equally as effective as the anti-cholesterol drug clofibrate.
That is not all, and other studies included one in which a decrease in LDL cholesterol of almost 13% was measured in a double blind study involving 61 subjects, of which around half received a placebo. An average 12.7% reduction in LDL cholesterol, 12% in triglycerides and 11.7% in total cholesterol was experienced by the group given the guggul extract. Every 1% drop in total cholesterol is associated with a 2% decrease in the risk of heart disease.
Guggul reduces the levels of harmful cholesterol in your blood by converting it into bile. The plant extract contains substances given the name guggulsterones that block the activity of a protein that regulates the metabolism of cholesterol in your body known as FXR (the Farsenoid X Receptor). This protein can increase the risk of you contracting heart disease by preventing the liver from converting cholesterol into bile acids, so that the concentration of cholesterol in your blood continues to build up.
The problem with bile acids is that once they reach a certain concentration in your body, the FXR comes into play and stops more being produced. Guggulsterones prevent the FXR from doing this, and so helps the liver to destroy more cholesterol. There is a reason for the body not allowing too much bile acid to be generated, but for those with excess cholesterol, it is more beneficial for this regulation to be prevented, and more cholesterol to be destroyed by the liver.
It is the resin of the plant that is prized, being extracted from the bark in much the same way as rubber is tapped. It is also used in fragrances and perfumes in addition to its medicinal uses, and the dosage generally recommended is 1500 mg (1.5 grams) twice daily. However, it is not recommended for those suffering liver disease, irritable bowel syndrome, Crohn's disease or any form of diarrhea, and should not be taken by those on beta blockers.
It is not only for its cholesterol-lowering properties that guggul is prized, however. Another property it possesses is its ability to render blood platelets less sticky, and so reduce the risk of coronary disease, and prevent the formation of blood clots and thrombosis.
Another use it has found is in the field of weight loss, where it has been found effective in reducing the weight of obese adults. It does so by the activation of lipolytic enzymes and increased levels of triiodothyronine (T3), believed to be due to the formation of T3 from T4 (thyroxine) in the liver.
T3 increases the metabolic rate, and the rate of the breakdown of glycogen and gluconeogenesis: the biosynthesis of glucose. It also causes cholesterol to be broken down and increases the rate of lipolysis - the breakdown of fats stored in fat cells in the body. Studies have shown that those taking guggul lost up to 6 times the weight of a control group within 15 days, and the practice is going along with the theory.
Not only that, but when you are on a diet, your body is likely to respond by decreasing levels of triiodothyronine, and so reducing the rate at which fat burns. Hence, your diet does not help you top reduce weight as quickly as it could. Guggul, however, stimulates the production of T3, and so you are not only taking less fat into your body, but are also burning it up at an accelerated rate.
Other uses to which the resin has been put are based upon its anti-inflammatory properties. It has been found to be an effective treatment for some forms of arthritis and also in the treatment of acne. The active inflammatory ingredient is believed to be myrrhanol A, a polypodane-type triterpene, which would also explain the antioxidant effect of guggulipid on lipid peroxidation.
Guggul is a versatile plant, and a good supplement to take for anybody suffering increased lipid or cholesterol levels, and who wants to increase the weigh-loss effect of their diet. However, make sure that you purchase a supplement standardized on its guggulipid content.
Green Coffee Bean Extract
October 22, 2008 04:59 PM
It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs.
The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition.
However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here.
The Free Radical Theory of Aging
Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them.
Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging.
Free radicals are generated in the body in four different ways:
1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher.
2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes.
3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting.
4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products.
In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body.
So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell.
Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron.
Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals.
It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol.
The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level.
Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging.
A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life.
There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.
Una de Gato (Cat’s Claw)
April 26, 2008 09:36 AM
Una de Gato, otherwise known as cat’s claw, is properly Unicaria tomentosa. It has been used as an herbal medicine for at least two thousand years by the people of Central and South America who gave it the name vilcacora.
It grows in jungle areas and rainforest in South America and Asia, and gets its name from the small claw-like thorns at the base of the leaves. One of the environmental benefits of the Una de Gato is that when it is harvested at three feet above the ground, it grows back to its full size of up to 100 feet within a few years when it can be harvested again to three feet. Cat’s claw has been given dietary supplement status by the FDA.
The Peruvian Asháninka tribe has used the plant as a contraceptive and for the treatment of rheumatic conditions, diabetes, acne, diarrhea, cancer, urinary tract diseases and as an anti-inflammatory, and many of the studies of cat’s claw have centered on this tribe. The studies quickly showed the active ingredients to be alkaloids, both tertracyclic oxindole alkaloids and pentacyclic alkaloids that have been found both in the bark and in the root.
The extract is obtained by boiling both the inner part of the bark and the root, each of which differs in concentration of the various alkaloids. The root is believed to better for its anti-inflammatory powers due to the quinovic acid glycoside it contains, although the relative concentrations of the various alkaloids can vary according to the time of year and to the chemotype of the plant.
Cat’s Claw comes in two chemotypes, each of which differs in the relative concentrations of the two different alkaloid types. One predominates in the pentacyclic alkaloids that strengthen the immune system, and the other chemotype in the tetracyclic alkaloids that counter that effect and reduce the speed and strength of the contractions of the heart. It is not possible to tell which chemotype a particular plant is until it has been chemically tested. They look exactly the same and it is possible for both to grow sided by side. However, the root is generally richer in alkaloids, and sells at about twice the price of the bark. Alkaloids are not the only active ingredients in Una de Gato, and it also contains tannins and phytochemicals that have an antioxidant effect and are useful free radical scavengers. They have been studied for their effects in the treatment of HIV and cancer, though mainly due to the glycoside content that will be discussed shortly. The National cancer Institute has confirmed some anti-cancer properties of quinovic glycosides derived from cat’s claw.
The four pentacyclic alkaloids have been found to have a boosting effect on the human immune system, which it does by enhancing the ability of the white blood cells and macrophages to digest and kill off foreign organisms and debris in tissue and the bloodstream. The inference is that the herb is able to be used to treat a wide variety of infectious diseases, including many immune and autoimmune conditions including AIDS. The results with AIDs are inconclusive, although one particular study showed that cat’s claw produced accelerated healing of cold sores and genital herpes (herpes simplex virus) and shingles (caused by herpes zoster virus). Although the evidence is slight, there are indications of its possible use in treating viral conditions.
It is used in homeopathy for the treatment of a number of digestive ailments, such as Crohn’s disease, leaky bowel syndrome, colitis, gastritis and gastric ulcers among others. It is also used in the treatment of inflammatory conditions such as arthritis, rheumatism and some conditions of the prostate gland.
The tertracyclic indole alkaloids that appear to counter the immune-boosting properties of their pentacyclic cousins include rhynchophylline, hirsutine, and mitraphylline. Rhynchophylline prevents blood clots in the veins and arteries by reducing the formation of platelets, and can dilate the peripheral blood vessels of the hands and feet. It can also lower blood cholesterol levels and reduce the heart rate. Due to this effect on blood vessels, it is though to be able to improve the circulation in the brain and be a useful treatment for Alzheimer’s sufferers. Hirsutine inhibits contractions of the smooth muscle of the bladder, and so finds uses in the treatment of urinary incontinence.
The pentacyclic alkaloids pteropodine and isopteropodine are believed to have important properties beyond their phagocytosis effect on the immune system. It has been reported that they have an effect on the 5-HT(2) receptors in the brain. These neurotransmitters are used as targets for many drugs used to treat a variety of conditions such as depression, eating disorders and anxiety, and such alkaloids have a positive modulating effect on them.
The anti-inflammatory properties of cat’s claw are largely due to the very potent quinovic acid glycosides previously referred to. These have been known about only recently, and they are thought to work synergistically to reduce the tissue swelling (edema) associated with the immune system’s inflammatory reaction. Although this is believed to be largely due to the glycosides, three of the alkaloids also possess anti-inflammatory properties. This property provides the scientific background for the traditional use of Una de Gato for rheumatism and arthritis, both inflammatory conditions. Many of the digestive conditions for which the plant has traditionally used are also inflammatory in nature.
A threat to cat’s claw is the destruction of the Peruvian rainforest, although not as much as a threat as the destruction of the plant itself. Cat’s claw has reached levels of popularity so high that it is in danger of extinction due to improper harvesting. New laws being enacted by the Peruvian government should help to protect the plant, and to promote its harvesting over cocoa.
When buying cat’s claw, make sure that it is the Uncaria tomentosa form you are purchasing since there is another type, Uncaria Guianensis that contains different alkaloids and is not as potent as the real Una de Gato. Also beware of a shrub known as cat’s claw acacia, grown in Mexico and the southwest USA, since it contains cyanide derivatives and could be very dangerous if taken by mouth.
Are You At Risk And What Can You Do About It?
April 23, 2008 04:54 PM
Did you know there are Persistent Organic Pollutants (POPs) that can have an endocrine disrupting ability? Meaning, these chemicals can have an estrogen like and anti-androgen effect on the body, disrupting the normal function of our endocrine system which can cause all sorts of health issues.
Back in the industrial boom directly following world war II these chemicals were widely used in plastics, cosmetics, personal care products, cleaning agents, clothing, household furnishings, and decorations, food and water, fertilizers, and pesticides and fungicides. These chemicals are being banned by the government but are not gone all together yet.
Endocrine disruptor chemicals are fat soluble which means when consumed they are stored by the body in our fat stores. This makes these chemicals a persistent pain in the butt for a very long time since fat soluble substances tend to be stored and slowly released; some claim the release can be years and years down the road.
These types of toxins can easily leach into water including juices and can vaporize into the air that we breathe in to our lungs. Once ingested, these chemicals can lead to reproductive, developmental, behavioral, neurological, endocrine, and immunologic adverse health effects that can last a lifetime.
Those men and women who want to have children may discover that one of both at have reproductive impairments due to POPs. Symptoms of toxicity are male infertility, gynecological problems, and accelerated puberty, developmental abnormalities of the reproductive tract, premature delivery, behavioral problems, abnormal thyroid function, cancer and heart disease. In cases of children, signs of toxicity are leukemia when fetal exposure is experienced.
The wide spread use of phthalates in industrial and consumer products has raised a lot of concerns. Phthalates are what keep plastics flexible. Dibutyl phthalate is used in PVC piping (in new homes the piping that supply water to faucets), various varnishes and lacquers, safety glass, nail polishes, paper coatings, dental materials, pharmaceuticals, children’s toys, and plastic food wrap. The heating of plastic containers either by microwave or a hot cup of tea can easily leach these phthalate’s in to food or drink exposing humans to high amounts of this toxin.
Also, Parabens are high on the watch list for those health minded. Parabens are a group of synthetic chemicals used as a preservative in cosmetic and pharmaceutical products. The most common parabens are methylparaben, propylparaben, and butylparaben. These three are used as a bacteriocidal and fungicidal agent in many products we use every day. The FDA does not require approval of cosmetic ingredients before they reach the market place so cosmetic manufactures are free to use what ever they want in their products.
Parabens have been shown to have a mild estrogenic affect on the body, and are in practically all personal care products on the market today. If you are applying a name brand cosmetic onto your skin daily, take a look at the label to see if Parabens are used.
For those looking to stay away form all the above listed toxins look for products packaged in glass, PETE or HDPE bottles and containers. Look for packets lined with saran, and can linings made of polyolefins. Use biodegradable household cleaning agents and avoid sprays and insecticides. Cleaning supplies are not required to list ingredients so it is always buyer beware unless the label states it is free from PCBs, Parabens, and POPs.
Finally, when buying furniture avoid furniture that contains flame retardant PBDEs and limit children to the exposure of such furniture. Exposure to PBDEs can lead to some of the above listed symptoms and cause health problems. Staying healthy is a tough task with all the environmental toxins we face. By buying organic foods and avoid the above listed chemicals one can live longer and maintain better health over a lifetime.
Broken Cell Chlorella - Single Celled Micro alga
April 21, 2008 05:06 PM
Chlorella is what is known as a micro alga, a single celled vegetable organism that grows in fresh water. Microalgae are microscopic species of plant life that are likely responsible for the biological evolutionary history of our planet. Most people associate algae with seaweed: marine plant life. However, this is a restricted view since algae are also common on land, although are rarely conspicuous and still require an aqueous environment if not necessarily a salt water ocean.
The reason for this is that algae have no vascular tissue to draw moisture up into the body of the plant as terrestrial plants do, and they tend to be found in tropical regions, on snow in areas of the Arctic and also on exposed areas of stone and rock in symbiosis with fungi in the form of lichens. They can also be found in freshwater ponds and rivers, and chlorella is one of these.
Its scientific name is Chlorella pyrenoidosa, and it occurs worldwide. It is said to have the highest concentration of chlorophyll of any other known plant in addition to its other highly nutritional content. The superlatives are almost limitless for such a small plant that most of the general population is unaware of. It is the first plant known to have a true nucleus, it has been around for about two and half billion years, and it can multiply itself fourfold making it the fastest growing species of plant known on earth. It beats other fast-growing algae and bamboo out of site.
So what of its nutritional content? It is believed by NASA to be the ultimate foodstuff for long-term travel in space and an ideal crop for colonizing communities. Were a space community to be established on Mars, chlorella would be the first to be cultivated under these big glass domes we all see in the movies! It is more than just a foodstuff though; it is also the most powerful known natural detoxifier for the human body, which makes it practically the ideal food. Why is this?
If any food deserves to be referred to as a ‘superfood’ it is chlorella. It consists of over 60% bioavailable protein, and contains six members of the vitamin B complex (1, 2, 3, 5, 6, 12) and also vitamins A, C, E and K. It is therefore very high in antioxidants and excellent for destroying free radicals as soon as they are formed, and before they can cause problems such as atherosclerosis and excessive cell damage.
It also contains more than its fair share of minerals such as calcium, manganese, magnesium, phosphorus and zinc, and also iodine, folic acid and a high proportion of iron. That is not all: it contains many more nutrients essential for a healthy life, but above all chlorella contains all eight essential amino acids.
Human biochemistry and metabolism need 20 amino acids to function properly, twelve of which can be manufactured by the liver from these eight: leucine, isoleucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine, and sometimes serine is added. These are called the essential amino acids from which all the others that your body needs can be manufactured.
Amino acids are needed to build proteins and DNA, manufacture body cells, repair damaged tissue, help the immune system to protect you from invading bacteria and viruses, ensure that the oxygen you breathe gets to the cells where it is needed to sustain life and carry out many other functions besides. Without them you could not exist. Chlorella contains five times more protein and amino acids than eggs do.
The Chlorella Growth Factor or CGF is a combination of these amino acids, together with nucleic acids, carbohydrates and peptides that have not yet been completely characterized. The CGF promotes the growth of body cells, and stimulates cell repair in a way not seen before in any other food. It has been shown to promote the growth of children in a natural and safe way.
Not only this, but it has been found not to promote the growth of diseased or cancerous cells, only healthy ones. The fact that that this accelerated growth does not happen with adults indicates that the Chlorella Growth Factor supports the natural growing process, although in adults it has been seen to accelerate the repair of damaged body tissue.
Chlorella also appears to strengthen the immune system, and researchers have found the presence of a polysaccharide in the cell walls of the microalgae that acts with CGF to produce an interferon that protects the helper cells that aid macrophages to destroy invading bacteria and viruses. It can help our resistance to influenza, choryza (common cold), fungi such as candida and many other forms of invasion by foreign agents into our bloodstream.
The detox effect of chlorella is largely contained within its cell walls that can bind with persistent toxic substances such as DDT, and bind with heavy metals to safely remove them from the body. In fact it is the ideal anti-toxin for life in today’s environment, full of vehicle exhaust fumes, pesticides and other chemical emissions. It has been claimed to be able to remove mercury from the body, but this has not been established.
Probably the only problem with the ingestion and the efficiency of the body to use Chlorella to its full extent is the strength of the cell walls. Chlorella has very strong cell walls, which could also account for the concentration of nutrients within them. the traditional method to overcome this was to mill them using small glass or ceramic beads to break the cell walls down, but the Japanese have come up with a more effective means. High frequency sound waves are used to break the cell walls down supersonically, a technique known as ‘cracking’, and once cracked the cells can release up to 65% of its nutrients, compared to the 50% of the milling method.
The nutritional content of single celled microalgae such as chlorella is amazing, and if the was only one food that you were able to eat, then this would be it. There is no other known species of plant or animal life that provides the range of vitamins, minerals, proteins and amino acids that chlorella does, and it truly is the king of all superfoods.
Increase Absorption Of Your Discount Vitamins With Bioperine
November 02, 2007 04:54 PM
In order to understand how you increase absorption of your discount vitamins with Bioperine, it is necessary to understand the metabolic process of thermogenesis. First, however, let’s have a look at what Bioperine is and where it comes from.
Bioperine is obtained from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper) of which it is a patented standardized extract. These peppers contain the alkaloid piperine, and the extract contains 95% piperine. The plants are grown in the ideal damp soil in regions of Southern India where the earth is rich in nutrients. The barriers are harvested just before ripening, and then dried in the hot sun before the extraction process is started. Piperine has many uses from flavoring to fly killer, but people have been using it for centuries to heal wounds though this is apparently unconnected with the use to which the extract is put.
It has recently been found to help increase the absorption of a number of discount vitamins and minerals, including Vitamin B, beta-carotene, and selenium, by increasing the thermogenic activity of the body. Thermogenesis is one of the metabolic processes of the body that takes place within our cells whereby glucose is converted to energy, but at an accelerated metabolic rate. It is the rise in the metabolic rate that is referred to as thermogenesis.
When you eat food, or take supplements, the metabolism increases above the normal rate, the amount of increase depending upon the type on nutrient taken. Fats will increase your metabolism at a lower rate than proteins will, for example, since more energy is needed to break down proteins than for fats. Another substance that stimulates thermogenesis is piperine. It does so by utilizing the biochemistry of the body so that the chemicals needed for thermogenesis are made available.
Piperine triggers the release of compounds known as catecholamines, hormones that in turn stimulate the thermogenetic process. However, this occurs over a short period of time, so the nutrients that are needed should be present in the gut as well since the window of absorption is very narrow. The substance also modifies the epithelial cell wall of the intestine to make it easier for the nutrients to be absorbed into the bloodstream, and it also gives amino acids a kick to get moving to the cells in which they are required.
Bioperine, then, not only sets off the metabolic changes that demand vitamins and other nutrients and enzymes, but also improves the conditions in your intestines so that these nutrients can more easily get to where they are needed. Basically, what Bioperine does is to cause the intestinal wall to become more permeable to nutrients, so that vitamins and drugs are not degraded when passing through the intestinal wall to the bloodstream. This improves digestion and absorption of minerals and vitamins, in addition to protein supplements frequently used in weight loss diets.
Bioperine starts by generating a need for nutrition and then increase the bioavailability of the nutrients provided to meet that need. However, due to the short window of absorption that piperine generates, the vitamins and minerals you want absorbed should be co-administered with the Bioperine so that they are in place ready to be absorbed at exactly the right time.
There have been several studies carried on the efficiency with which piperine achieves this. The absorption of three different types of nutrients has been measured with and without Bioperine. These were beta-carotene, a fat soluble vitamin, vitamin B-6, a water soluble vitamin, and also a mineral, selenium which was provided as selenomethionine. The absorption of these by the digestive system was measured by detecting them before and after in the blood, and were found to increase considerably when taken along with Bioperine, but not so with the control group without it.
Measured increases were a 60% increase in beta-carotene, similar to that of vitamin B-6, and was 30% in selenium. The tests used a 5 mg dose of the Bioperine. Other studies have indicated an increase in the absorption of Coenzyme Q-10 of between 30% - 200%. This is the only piperine based product that has been patented for its effect in increasing the absorption of nutrients into the body, and also the only piperine based product to undergo such tests in the U.S. to substantiate its claims and prove its safety for use.
The black pepper itself is a common household spice, and has been used in India for its medicinal properties for centuries. It is mentioned in the practice of Ayurveda and its concentration on the function of the digestive tract in human health. Many of its formulas contain black pepper amongst their ingredients. The bioavailability of nutrients is a significant factor in the health of any specific population, and the exponents of Ayurveda overcame this problem, by chance or design, six millennia ago. It has been demonstrated time and time again that diet is not the factor of importance in nutrition, but how much of that diet is absorbed through the intestines.
This is yet another example of the medicines of our ancestors being shown to have a solid scientific basis, and perhaps we should pay more attention to those others that are disregarded by modern science. It could be that we have only scratched the surface of understanding human metabolism and biochemistry, and that there is much left to learn. Ancient wisdom should never be disregarded.
Bioperine is also available in many supplement mixtures so that it is taken at the same time as the relevant vitamins and minerals. The recommended dosage is from 1 mg – 5 mg from 2 – 3 times daily. It takes around 2 – 5 mg of Bioperine to provide sufficient enhancement of absorption of the nutrients that are taken with it. Keep in mind that the nutrients are best taken at the same time, and that taking the extract itself will simple increase the absorption of any nutrients that are in the intestine at that time. Bioperine can be purchased at your local or internet vitamin store.
How to remineralize the Earth – Getting vital nutrients back into the soil
June 26, 2007 01:55 PM
We know that “traditionally grown” fruits and vegetables we see in supermarkets are both lacking in vitamins and minerals and have added chemicals from fertilizers and pesticides. These toxic additions in particular fueled the demand for organic produce but did not completely address the lack of nutrients.
Going back in time, our soil was rich with minerals, which found their way into our foods in healthy doses. Mineralized soil grew healthier crops providing the vitamins and minerals we now need to take as supplements. Additionally, hardier plants were capable of repelling insects and other pests that are now a constant and costly threat to growers.
Over the years (and accelerated with the advent of modern industrialized farming), soil all over the planet has become depleted of minerals, resulting in crops and forests that struggle to perform their parts in our ecology—either providing nutrition or, in the case of trees, putting vital oxygen back into our atmosphere.
It’s a serious problem. A recent report based on U.S. agricultural records has found that the nutrient content of fruits an vegetables has been dropping since these records were first taken in the early 1960’s—just over 40 years ago. To illustrate the point, we would need to eat five apples today just to get the same nutrients we would of found in one apple in 1965.
Exceptional Ingredients For Exceptional Performance
June 02, 2007 02:52 PM
Anaerobic exercises, such as bodybuilding and strength training, as well as endurance based aerobic activities, such as marathon running and bicycling, are notorious for depleting the body’s reserves of glycogen, protein, electrolyte minerals, water, and other vital constituents. And as simple logic will tell us, the harder one trains, the more they will lose in the process. Failure to properly replenish these nutrients immediately after training can result in fatigue, delayed recovery, accelerated lactic acid levels, mental sluggishness, and intense soreness. According to research, immediate replacement of electrolyte minerals and carbohydrates, along with easily assimilated protein is an effective way to maximize amino acid utilization, when preventing the onset of fatigue. NOW Electro Pro Energy Drink contains all the elements to ensure proper post-workout recovery. By combining a perfectly balanced mix of electrolytes, protein and simple and complex carbohydrates, Electro Pro serves as an ideal supplement for recovering after intense training and exercise.*
This patented casein hydrolysate was scientifically formulated to provide athletes with a better source of protein for faster recovery, more efficient glycogen usage, better insulin response, and less fatigue. PeptoPro helps stimulate the body’s own natural production of insulin to help increase glucose uptake to hard working muscle cells. Its high dipeptide and tripeptide profile promotes fast absorption, and has been shown in human trials to accelerate muscle recovery. PeptoPro contains all 20 amino acids in the natural ratio of casein, a key factor in preventing muscle fatigue and muscle tissue damage because it is a predigested protein, PeptoPro is ideal for taking before and after workouts.
During intense exercise, the body quickly exhausts its reserve of electrolytes. If these aren’t replenished promptly, the body will fatigue at a very fast rate, and may dehydrate. Electro Pro contains calcium, magnesium, sodium and potassium to help fuel even the most intense training session.
Carbohydrates are vital when it comes to providing the glycogen that is needed to fuel and refuel today’s athlete. Electro Pro contains a unique blend of dextrose, fructose and rice Maltodextrin to ensure that the body has a generous fuel source. Every serving contains 32 grams of quality carbohydrates.
Electrolyte Energy Formula
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
October 31, 2006 03:37 PM
Prickly Pear Extract for Endurance and Stamina
• Contains Tex-OE™, a patented extract from the nopal cactus.
Source Naturals opal contains Tex-OE™, a patented standardized extract from the prickly pear or nopal cactus that helps support endurance and stamina by priming the body for athletic activity and physical exertion. Preliminary evidence suggests that Tex-OE™ may support the accelerated formation of Heat Shock Proteins (HSTs), stress recovery proteins synthesized by the body to endure physiological extremes. This early response helps to minimize cellular damage as a result of extreme physical exertion. Source NaturalsNopal Endurance is a critical step toward achieving maximum potential.
1 capsule contains:
Prickly Pear Fruit Standardized Extract 40 mg (Tex-OE™ a patented extract of Opuntia ficus)
Suggested Use: 1 capsule per 130 lbs of body weight, with water, at least 2 hours before stress activity, once every three days. Fiber interferes with absorption. For best results, do not eat or drink foods or beverages containing fiber 2 hours before and 2 hours after taking.
7-Syndrom Healing and 5-HTP
June 07, 2006 03:49 PM
Boomer Breakthrough – Keeping in the Game
If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves.
Mood, Anxiety and Depression
Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use.
How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels.
Serotonin the Antiaging Neurotransmitter
Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients.
Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period.
5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin.
It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia.
Pain, Per-menopause and PMS
5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants.
Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability.
Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller.
Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety.
Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain.
Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.
Spectral DNC for Hair Loss (Minoxidil 5%)
February 25, 2006 01:54 PM
December 29, 2005 12:06 PM
Did you know that poor digestive function is a contributing factor in more than ninety percent of America’s serious health issues?! The waiting rooms of doctors are jam packed, in part because so many people are suffering with gastrointestinal problems. The medical establishment and alternative health and wellness practitioners don’t always agree, but both sides are certain that a healthy digestive system is the cornerstone of good health. Proteins, the building blocks of life; carbohydrates and fats, your body’s source of energy; vitamins and minerals; and water – all are assimilated through digestion. If you’re not properly digesting the foods you eat, your body isn’t obtaining the nutrients it needs to repair, renew and thrive. Without the raw materials it needs to repair the damage we do to ourselves every day, your body begins to break down, leading to poor health and accelerated aging2,3.
While there are a multitude of factors involved in healthy digestive function, one of the most important is the delicate balance of bacteria found in the human gastrointestinal (GI) tract. There are three main types of flora in the human GI tract - Bifidobacteria, Bacteroides and Eubacterium. Of slightly less importance are Lactobacilli, Streptococci and Peptococci and other transitory flora1. Our stomachs and intestines are populated by hundreds of billions of these bacteria, or microflora. Amazingly, there are more probiotic organisms in our gut than there are cells in our bodies! That’s a lot of bacteria, but it’s GOOD bacteria, and each strain has specific functions in the human body. These bacteria aid the digestion of food and have protective qualities that contribute to good colon health. While a good balance of these different microflora is necessary, there are many factors that can, and do, disrupt this balance –certain medications, a poor diet, infection, stress, bad bacteria, aging and even the climate. The good news is a rapidly expanding body of research suggests that supplementing the diet with the right mix of microflora can have a beneficial affect on gastrointestinal function, and therefore overall health.
NOW® Gr8-Dophilus™ exclusively utilizes the finest strains from Rhodia Incorporated, the world’s leading supplier of high quality probiotic ingredients, and is enteric-coated to ensure that the bacteria in this product are not destroyed in stomach acid but reach the small and large intestines where they are most beneficial. Gr8-Dophilus is a vegetarian product that contains virtually no lactose.
Lactobacillus acidophilus is a well-studied microflora species that’s highly resistant to gastric acidity and is able to proliferate in the presence of bile. Like many probiotic organisms, it also adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.
Lactobacillus casei is a microflora strain that is found in the human mouth and intestines as well as in fermented vegetables, milk and meat. Recent research has shown that this bacterium is active in the GI tract and may help to modulate the immune system*. Research is continuing into this very promising probiotic.
Lactobacillus rhamnosus, like Lactobacillus acidophilus, is highly resistant to gastric acidity and proliferates well in bile. It, too, adheres well to intestinal cells. We’ve included this particular strain because it works extremely well with L. acidophilus. Lactobacillus salivarius is a strain that has proven highly effective against Helicobacter pylori, a bacterial species implicated in a number of digestive conditions. Studies have shown that L. salivarius is capable of producing high amounts of lactic acid, which has been shown to inhibit H. pylori growth in live subjects. Compared to other Lactobacillus strains, L. salivarius was proven to have the greatest inhibitory effect on the proliferation of H. pylori,4 which is why this strain is included in Gr8-Dophilus™.
Streptococcus thermophilus bacterium are isolated from yogurt and are recommended for lactose intolerant individuals to help digest lactose in the intestines. This strain is included in this formula to assist in the acidification of the intestinal environment, as well as to create a favorable environment for lactic acid bacteria.
Bifidobacterium bifidum is one of the workhorses of the large intestine. It has a high tolerance to gastric acidity, and, like L. acidophilus and many other probiotic organisms, it adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.
Bifidobacterium longum is a bifidobacterium of human origin that, like lactobacillus, is extremely resistant to gastric acid and bile salts. Because it’s anaerobic (able to live without oxygen) it’s perfectly suited to colonize the colon. Initial studies have shown that this particular strain of bifidobacteria helps to support the immune system*. It also seems to decrease enzymatic activity in feces. Researchers believe enzymatic activity in feces may contribute to carcinogenesis.
Bifidobacterium lactis is one of the most well-studied strains of probiotic bacteria, with a wealth of peer-reviewed, published research on its benefits. Clinical trials on B. lactis have shown it to be helpful in a number of digestive conditions, including diarrhea and lactose intolerance, as well as immune response modulation.
GliSODin Anti-Aging and Antioxidant Protection
December 19, 2005 08:47 AM
GliSODin Anti-Aging and Antioxidant Protection
In the time it takes you to finish reading this article, you, your body and your cells will have aged. Some, more than others. Nevertheless, every second that ticks away should serve as a reminder that our time here is temporary. How much time we actually end up with depends on many things. Diet. Lifestyle. Environment. Superoxide Dismutase? I’ll explain. What some of the healthiest individuals fail to realize is that our bodies age from the inside out. Aging is not the result of passing time, but rather the result of what we’re exposed to environmentally, physically and chemically. It is the integrity of our cells, not our clocks, that determine how smooth the aging process fares.
Each day, we’re subjected to millions of elements that affect us in ways seldom seen, felt or noticed. From the moment we’re born, we rely on our cells to work around the clock - producing energy, fighting infections and sustaining life. These same cells eventually determine the rate at which we show (or hide) our age.
Taking into consideration that our planet has no shortage of toxins & germs, the need to safeguard our cells becomes very real. Constant exposure to exhaust, secondhand smoke, heavy metals, lead, fluoride and uncountable other noxious compounds should ideally provide us with nothing more than a routine immune system workout. Unfortunately, over long periods they hinder our “resistance” abilities and become stepping stones to accelerated aging.
Antioxidants. We’ve all heard the term before, and may even have a general understanding of their role. But to better grasp just how vital they are, it helps to know what’s happening at the cellular level. Free radicals are unstable molecular thieves that often lack electrons. To compensate, they rob healthy cells - a process better known as oxidation. Antioxidants work with the immune system to prevent oxidation, and clean up the mess it leaves behind. Hence, the name.
There are two types. Exogenous antioxidants are derived from our diet and include vitamins A, E, and C along with others such as alpha lipoic acid, selenium, CoQ10, grape seed, pycnogenol and zinc. To date, we’ve been limited to exogenous antioxidants as a way to increase the rate at which our body wards off oxidation. They are not, however, our first line of defense. At birth, each and every one of us is equipped with three primary endogenous enzymatic antioxidants; SOD (Superoxide Dismutase), Glutathione Peroxidase (GPx) and Catalase.
While both types of antioxidants are beneficial, we’ve become reliant on those from the diet to compensate for our inability to boost the effectiveness of our 3 primary antioxidants. For years, researchers have been examining ways to enhance the activity of our built-in bodyguards. One in particular, Superoxide Dismutase (SOD) has been of foremost interest. SOD targets what many researchers regard as one of our greatest health threats and aging accelerators - Superoxide radicals. These highly reactive, merciless molecules incite enormous amounts of oxidative stress and are capable of wreaking havoc on healthy cells. When cells are left unprotected by SOD, the results can be disastrous - respiratory problems, premature aging, memory loss, cardiovascular challenges, vision failure and joint structure damage, among others.
Until now, we’ve been at the mercy of our natural SOD reserves to fight superoxides. Researchers have been working feverishly to produce an effective oral SOD supplement, but have continually encountered a frustrating hurdle - exposure to gastric acid denatures SOD, rendering it useless. As a result, the only effective way to supplement SOD was through injections. These, however, only yielded short-term spikes. And then something remarkable happened that changed everything. Nutrition scientists in France determined that by combining Cucumus melo (a melon high in SOD) with a wheat gliadin stabilizer, it would be possible to prevent SOD from deteriorating in the digestive tract, while preserving it in the blood for extended periods. Not only is this the answer to a puzzle that has plagued researchers, it’s a breakthrough that will impact the life of anyone seeking longevity and vitality.
As the first proven oral SOD supplement ever introduced to the public, GliSODin® has taken antioxidant protection, immune support and antiaging science to an entirely new level. The primary function of GliSODin® is to scour the body for superoxide radicals and reduce them to less reactive ions that can be swept away; a process known as dismutation. In addition, GliSODin® reduces the oxidation vulnerability of healthy cells, protects mitochondrial activity and safeguards DNA structure.
What’s most remarkable is that GliSODin® has actually been shown to stimulate the body’s own natural production of all three enzymatic antioxidants, including SOD. For the first time in history, we will have the ability to enhance the effectiveness of our body’s primary defense mechanism.
New GliSODin® from NOW® represents the ultimate in antioxidant protection. By increasing one’s level of SOD while stimulating the natural production of Glutathione Peroxidase and Catalase, GliSODin® delivers antioxidant protection unlike any previously released dietary supplement. Remember, the aging process begins at a level that we simply can not see, the cellular level. Shielding your cells from superoxide damage is one of the smartest steps you can take against aging before your due time. GliSODin® has made this a reality.
Psyllium Husk Fiber Fact Sheet
December 08, 2005 04:28 PM
Psyllium Husk Fiber Fact SheetNeil E. Levin, CCN, DANLA 8/1/05
LIKELY USERS: People with cholesterol or cardiovascular concerns.1-2 People wanting to increase fiber in their diet3-9
KEY INGREDIENTS: Psyllium Husk Powder, natural flavor
MAIN PRODUCT FEATURES: Psyllium is a true dietary fiber, even though it is classified by some as a laxative or mucilaginous fiber, and is a convenient way to increase intake of dietary fiber because of its high mucilage content. This bulking agent swells considerably when added to liquid, which can help to increase gastrointestinal transit time. This bulking action and increased transit time can play an important role in maintaining healthy gastrointestinal function.3-9 The FDA allows a health claim for products like psyllium husk that provide significant amounts of soluble fiber: Diets low in saturated fat and cholesterol that include 1.7 grams of soluble fiber per day from psyllium husk may reduce the risk of heart disease. One serving of NOW Psyllium Husk Fiber - Orange Flavored provides 2 grams of this soluble fiber.1-2
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: This product has been tested by an independent laboratory to assay the fiber content. This is a vegetarian/vegan product.
SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, mix 1 heaping teaspoon into at least 12 oz. of water or juice and consume immediately. Be sure to drink plenty of additional fluids throughout the day. Start with smaller amounts and gradually increase over several weeks.
For GI tract: Triphala, Detox Support, Probiotics, FOS, and healthy oils (fish, flax, olive, virgin coconut, virgin macadamia)
For cardiovascular health: Hawthorn extract, Tru-E Bio Complex (new September 2005), Heart Support, Heart Renew, Cholesterol Support, Cholestatin, Policosanol. Red Yeast Rice CAUTIONS: None.
SPECIFIC: Do not use if you have a bowel obstruction or an ulcer. If you have chronic constipation, diabetes or are obese a physician should monitor the use of this dietary supplement. Side effects are possible with any dietary supplement. This dietary supplement may cause gastrointestinal pain, flatulence and abdominal pain. Tell your doctor if these side effects become severe or do not go away.
NOTICE: This food should be eaten with at least a full glass of liquid. Eating this product without enough liquid may cause choking. Do not eat this product if your have difficulty in swallowing.
GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
1. [Code of Federal Regulations] [Title 21, Volume 2] [Revised as of April 1, 2002]
October 06, 2005 10:08 PM
Magnesium is a dietary mineral with a wide array of biological activities in the body. Magnesium participates in numerous life-essential processes that occur both inside and outside cells. Magnesium deficiency impacts normal physiologic function on many levels. Adequate magnesium is a fundamental requirement for optimum function of the cardiovascular system, the nervous system and skeletal muscle, as well as the uterus and GI tract. Magnesium deficiency can affect health of the heart, bones and blood vessels and alter blood sugar balance .
Magnesium–Important for Everyone, Deficient in Many The average person living in a modern country today very likely consumes less than the optimum amount of magnesium . An abundance of data collected over the last two decades shows a consistent pattern of low magnesium intake in the U.S. This pattern cuts a wide swath across various age-sex groups. The USDA’s Nationwide Food Consumption Survey found that a majority of Americans consumed less than the recommended daily magnesium intake . Twelve age-sex groups were studied and this low magnesium intake was true for all groups except 0 to 5 year olds.
An analysis of the nutrient content of the diets of 7,810 individuals age four and above included magnesium among several nutrients where the amounts supplied by the average diet "were not sufficient to meet recommended standards" . The FDA’s Total Diet study examined the intakes of eleven minerals, including magnesium, among eight age-sex groups. Data was collected four times yearly from 1982 to 1984. Levels of magnesium, calcium, iron, zinc and copper were low for most age-sex groups . Surveys conducted in Europe and in other parts of North America paint a similar picture. Loss of magnesium during food processing is one explanation for this global lack of adequate dietary magnesium .
In particular, the elderly may be susceptible to magnesium deficiency for a variety of reasons, including inadequate magnesium intake, poor absorption due to impaired gastrointestinal function and use of drugs such as diuretics that deplete magnesium from the body . It has recently been theorized that magnesium deficiency may contribute to accelerated aging, through effects on the cardiovascular and nervous systems, as well as muscles and the kidneys .
Women who take both synthetic estrogen and calcium supplements may be at risk for low blood levels of magnesium . Estrogen promotes the transfer of magnesium from blood to soft–tissues. Low blood magnesium may result if the ratio of calcium to magnesium intake exceeds 4 to 1. Magnesium supplementation is thus advisable for women taking estrogen and calcium.
Young adults are not immune to magnesium deficiency. The University of California’s Bogalusa Heart Study collected nutritional data from a cross-sectional sample of 504 young adults between age 19 and 28 . The reported intake of magnesium, along with several other minerals and vitamins, was below the RDA.
Glycine is a highly effective mineral chelator. This is because it is a low-molecular-weight amino acid, hence is easily transported across the intestinal membrane. A study conducted at Weber State University found this particular magnesium glycinate was absorbed up to four times more effectively than typical magnesium supplements.
Magnesium-the Versatile Mineral
The average adult body contains anywhere from about 21 to 28 grams of magnesium. Approximately 60 percent of the body’s magnesium supply is stored in bone. Soft tissue, such as skeletal muscle, contains 38%, leaving only about 1 to 2% of the total body magnesium content in blood plasma and red blood cells. Magnesium in the body may be bound either to proteins or "anions" (negatively charged substances.) About 55% of the body’s magnesium content is in the "ionic" form, which means it carries an electrical charge. Magnesium ions are "cations," ions that carry a positive charge. In its charged state, magnesium functions as one of the mineral "electrolytes."
Magnesium works as a "co-factor" for over 300 enzymatic reactions in the body. Metabolism uses a phosphate containing molecule called "ATP" as its energy source. Magnesium is required for all reactions involving ATP . ATP supplies the energy for physical activity, by releasing energy stored in "phosphate bonds".
Skeletal and heart muscle use up large amounts of ATP. The energy for muscle contraction is released when one of ATP’s phosphate bonds is broken, in a reaction that produces ADP. Phosphate is added back to ADP, re-forming ATP. ATP also powers the cellular "calcium pump" which allows muscle cells to relax. Because it participates in these ATP-controlled processes, magnesium is vitally important for muscle contraction and relaxation. By controlling the flow of sodium, potassium and calcium in and out of cells, magnesium regulates the function of nerves as well as muscles .
Magnesium’s importance for heart health is widely recognized. The heart is the only muscle in the body that generates its own electrical impulses. Through its influence on the heart’s electrical conduction system, magnesium is essential for maintenance of a smooth, regular heartbeat . Magnesium appears to help the heart resist the effects of systemic stress. Magnesium deficiency aggravates cardiac damage due to acute systemic stress (such as caused by infection or trauma), while magnesium supplementation protects the heart against stress . This has been found true even in the absence of an actual magnesium deficit in the body.
Evidence suggests that magnesium may help support mineral bone density in elderly women. In a two-year open, controlled trial, 22 out of a group of 31 postmenopausal women who took daily magnesium supplements showed gains in bone density. A control group of 23 women who declined taking the supplements had decreases in bone density . The dietary intakes of magnesium, potassium, fruit and vegetables are associated with increased bone density in elderly women and men . In an interesting animal study, rats were fed diets with either high or low levels of magnesium. Compared to the high magnesium-fed rats, bone strength and magnesium content of bone decreased in the low-magnesium rats, even though these rats showed no visible signs of magnesium deficiency . While this finding may or may not apply to humans, it raises the possibility that diets supplying low magnesium intakes may contribute to weakening of bone in the elderly.
Maximizing Absorption––Chelated Minerals Explained Mineral absorption occurs mainly in the small intestine. Like any mineral, magnesium may be absorbed as an "ion," a mineral in its elemental state that carries an electric charge. Mineral ions cross the intestinal membrane either through "active transport" by a protein carrier imbedded in the cells lining the membrane inner wall, or by simple diffusion. The magnesium in mineral salts is absorbed in ionic form. However, absorption of ionic minerals can be compromised by any number of factors, including: 1) Low solubility of the starting salt, which inhibits release of the mineral ion, and 2) Binding of the released ion to naturally occurring dietary factors such as phytates, fats and other minerals that form indigestible mineral complexes .
A second absorption mechanism has been discovered for minerals. Experiments have shown that minerals chemically bonded to amino acids (building blocks of protein) are absorbed differently from mineral ions. This has given rise to the introduction of "chelated" minerals as dietary supplements. Mineral amino acid chelates consist of a single atom of elemental mineral that is surrounded by two or more amino acid molecules in a stable, ring-like structure.
Unlike mineral salts, which must be digested by stomach acid before the desired mineral portion can be released and absorbed, mineral chelates are not broken down in the stomach or intestines. Instead, chelates cross the intestinal wall intact, carrying the mineral tightly bound and hidden within the amino acid ring. The mineral is then released into the bloodstream for use by the body. Research by pioneers in the field of mineral chelation and human nutrition indicates that the best-absorbed chelates consist of one mineral atom chelated with two amino acids. This form of chelate is called a "di-peptide." Compared to other chelates, di-peptides have the ideal chemical attributes for optimum absorption . Dipeptide chelates demonstrate superior absorption compared to mineral salts. For example, a magnesium di-peptide chelate was shown to be four times better absorbed than magnesium oxide .
Consumer Alert! Not all "amino acid chelates" are true chelates. In order for a mineral supplement to qualify as a genuine chelate, it must be carefully processed to ensure the mineral is chemically bonded to the amino acids in a stable molecule with the right characteristics. The magnesium bis-glycinate/lysinate in High Absorption Magnesium is a genuine di-peptide chelate ("bis" means "two"). It has a molecular weight of 324 daltons, considerably lower than the upper limit of 800 daltons stated in the definition of "mineral amino acid chelates" adopted by the National Nutritional Foods Association in 1996 .
Bioperine® For Enhanced Absorption Bioperine® is a natural extract derived from black pepper that increases nutrient absorption.* Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine® .
Scientific References 1. Abbott, L.R., R., Clinical manifestations of magnesium deficiency. Miner electrolyte Metab, 1993. 19: p. 314-22. 2. Durlach, J., Recommended dietary amounts of magnesium: Mg RDA. Magnesium Research, 1989. 2(3): p. 195-202. 3. Morgan, K.e.a., Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition, 1985. 4: p. 195-206. 4. Windham, C., Wyse, B., Hurst, R. Hansen, R., Consistency of nutrient consumption patterns in the United States. J AM Diet Assoc, 1981. 78(6): p. 587-95. 5. Pennington, J., Mineral content of foods and total diets: the Selected Minerals in Food Survey, 1982 to 1984. J AM Diet Assoc, 1986. 86(7): p. 876-91. 6. Marier, J., Magnesium Content of the Food Supply in the Modern- Day World. Magnesium, 1986. 5: p. 1-8. 7. Costello, R., Moser-Veillon, P., A review of magnesium intake in the elderly. A cause for concern? Magnesium Research, 1992. 5(1): p. 61-67. 8. Durlach, J., et al., Magnesium status and aging: An update. Magnesium Research, 1997. 11(1): p. 25-42. 9. Seelig, M., Increased need for magnesium with the use of combined oestrogen and calcium for osteoporosis treatment. Magnesium Research, 1990. 3(3): p. 197-215. 10. Zive, M., et al., Marginal vitamin and mineral intakes of young adults: the Bogalusa Heart Study. J Adolesc, 1996. 19(1): p. 39-47. 11. McLean, R., Magnesium and its therapeutic uses: A review. American Journal of Medicine, 1994. 96: p. 63-76. 12. Graber, T., Role of magnesium in health and disease. Comprehensive Therapy, 1987. 13(1): p. 29-35. 13. Sueta, C., Patterson, J., Adams, K., Antiarrhythmic action of pharmacological administration of magnesium in heart failure: A critical review of new data. Magnesium Research, 1995. 8(4): p. 389- 401. 14. Classen, H.-G., Systemic stress, magnesium status and cardiovascular damage. Magnesium, 1986. 5: p. 105-110. 15. Stendig-Lindberg, G., Tepper, R., Leichter, I., Trabecular bone density in a two year controlled trial of peroral magnesium in osteoporosis. Magnesium Research, 1993. 6(2): p. 155-63. 16. Tucker, K., et al., Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr, 1999. 69(4): p. 727-736. 17. Heroux, O., Peter, D., Tanner, A., Effect of a chronic suboptimal intake of magnesium on magnesium and calcium content of bone and bone strength of the rat. Can J. Physiol. Pharmacol., 1975. 53: p. 304-310. 18. Pineda, O., Ashmead, H.D., Effectiveness of treatment of irondeficiency anemia in infants and young children with ferrous bisglycinate chelate. Nutrition, 2001. 17: p. 381-84. 19. Adibi, A., Intestinal transport of dipetides in man: Relative importance of hydrolysis and intact absorption. J Clin Invest, 1971. 50: p. 2266-75. 20. Ashmead, H.D., Graff, D., Ashmead, H., Intestinal Absorption of Metal Ions and Chelates. 1985, Springfield, Illinois: Charles C. Thomas. 21. NNFA definition of mineral amino acid chlelates, in NNFA Today. 1996. p. 15. 22. Bioperine-Nature's Bioavailability Enhancing Thermonutrient. 1996, Sabinsa Corporation: Piscataway, N.J.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Doctor's Best•1120 Calle Cordillera•Suite 101, San Clemente, CA 92673
Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)
August 02, 2005 03:52 PM
Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine.4
Thiamine and its Co-enzyme, TPP
Thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically-catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name "thiamine diphosphate." In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as "active acetate." Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb’s cycle (citric acid cycle). The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called "oxidative decarboxylation," and for this reason, TPP was originally referred to as "cocarboxylase." TPP is thus vital to the cell’s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below.
Benfotiamine and Glucose Metabolism Benfotiamine normalizes cellular processes fueled by glucose metabolites.
As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell’s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the Krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.5 In the presence of elevated glucose levels, the electron transport chain, the final ATP-generating system in the mitochondrion, produces larger than normal amounts of the oxygen free radical "superoxide." This excess superoxide inhibits glyceraldehyde phosphate dehydrogenase (GAPDH), as key enzyme in the conversion of glucose to pyruvic acid, resulting in an excess of intermediate metabolites known as "triosephosphates." Increase triosephophate levels trigger several cellular mechanisms that result in potential damage to vascular tissue. Cells particularly vulnerable to this biochemical dysfunction are found in the retina, kidneys and nerves.
Benfotiamine has been shown to block three of these mechanisms: the hexosamine pathway, the diaglycerol-protein kinease C pathway and the formation of Advanced Glycation End-poducts. As discussed below, benfotiamine does this by activating transketolase, a key thiamin-dependent enzyme.6 Benfotiamine stimulates tranketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.* Transketolase diverts the excess fructose-6-phosphate and glyceraldehydes-3-phosphate, (formed by the inhibition of GAPDH, as mentioned above), into production of pentose-5-phosphates and erythrose-4-phosphate and away from the damaging pathways. Benfotiamine activates transketolase activity in bovine aortic endothelial cells incubated in glucose.6 To test benfotiamine’s ability to counteract these metabolic abnormalities caused by elevated blood glucose, studies have been done in diabetic rats. Benfotiamine increases transketolase activity in the retinas of diabetic rats, while concomitantly decreasing hexosamine pathway activity, protein kinase C activity and AGE formation.6
Benfotiamine and Protein glycation Benfotiamine controls formation of Advanced Glycation End-products (AGEs).
AGEs have an affinity for proteins such as collagen, the major structural protein in connective tissue. AGEs are formed through abnormal linkages between proteins and glucose. This occurs via a non-enzymatic glycosylation reaction similar to the "browning reaction" that takes place in stored food.7 At high glucose concentrations, glucose attaches to lysine, forming a Schiff base, which in turn forms "early glycosylation products." Once blood glucose levels return to normal levels, the amount of these early glycosylation products decreases, and they are not particularly harmful to most tissue proteins. On long-lived proteins such as collagen, however, early glycosylation products are chemically rearranged into the damaging Advanced Glycation End-products. AGE formation on the collagen in coronary arteries causes increased vascular permeability. This vessel "leakiness" allows for abnormal cross-linking between plasma proteins and other proteins in the vessel wall, comprising vascular function and potentially occluding the vessel lumen. A number of other potentially harmful events may also occur, including production of cytokines that further increase vascular permeability. Endothelin-1, a strong vasoconstrictor, is over produced, increasing the possibility of thrombosis and generation of oxygen free radicals is stimulated.8 It is vitally important to support normal glucose metabolic pathways so that formation of AGEs is minimized. Benfotiamine, in the test tube (in vitro) prevents AGE formation in endothelial cells cultured in high glucose by decreasing the glucose metabolites that produce AGEs.9 Endothelial cells make up the membranes that line the inner walls of organs and blood vessels. In a rat study comparing the effects of Benfotiamine with water-soluble thiamin, Benfotiamine inhibited AGE formation in diabetic rats while completely preventing formation of "glycooxidation products," which are toxic by products of chronic elevated blood glucose. AGE levels were not significantly altered by thiamin.10 Benfotiamine also normalized nerve function in the animals. After three months of administration, "nerve conduction velocity (NCV)," a measure of nerve function, was increased by both benfotiamine and thiamin; at six months, NCV was normalized by benfotiamine, whereas thiamin produced no further increases in this parameter.
Dysfunctional glucose metabolic pathways leading to AGE formation occurs in endothelial cells of the kidneys. In a recent animal study, benfotiamine was administered to rats with elevated glucose levels. Benfotiamine increased transketolase activity in the kidney filtration system of these rats, while at the same time shifting triosephophates into the pentose pathway and preventing protein leakage.11
Benfotiamine has an excellent tolerability profile and can be taken for long periods without adverse effects.3,12 The statements in this fact sheet have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
1. Bitsch R, Wolf M, Möller J. Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative. Ann Nutr Metab 1991;35(2):292-6.
2. Schreeb KH, Freudenthaler S, Vormfelde SV, et al. Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate. Eur J Clin Pharmacol 1997; 52(4):319-20.
3. Loew D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin Pharmacol Ther 1996;34(2):47-50.
4. Frank T, Bitsch R, Maiwald J, Stein G. High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. Eur J Clin Pharmacol. 2000;56(3):251-7.
5. Pike RL, Brown ML. Nutrition, An Integrated Approach, 3rd Ed. New York:MacMillan; 1986:467.
6. Hammes H-P, Du X, Edlestein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic neuropathy. Nat Med 2003;9(3):294-99.
7. Monnier VM, Kohn RR, Cerami A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci 1984;81(2):583-7.
8. Brownlee M. The pathological implications of protein glycation. Clin Invest Med 1995;18(4):275-81.
9. Pomero F, Molinar Min A, La Selva M, et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol 2001;38(3):135-8.
10. Stracke H, Hammes HP, Werkman D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes 2001;109(6):300-6.
11. Babaei-Jadidi R, Karachalias N, Ahmed N, et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 2003;52(8):2110-20.
12. Bergfeld R, MatsumaraT, Du X, Brownlee M. Benfotiamin prevents the consequences of hyperglycemia induced mitochondrial overproduction of reactive oxygen specifies and experimental diabetic neuropathy (Abstract) Diabetologia 2001; 44(Suppl1):A39.
PYCNOGENOL - MIRACLE ANTIOXIDANT
July 13, 2005 09:36 AM
Virtually each and every day, most of us are exposed to a number of toxic substances. Au to Exhaust, tobacco smoke , pollution, preservatives, and additives continually assault our bio-cellular systems. As a result, our risk of getting a degenerative disease is significantly increased. In addition, the aging process itself is accelerated by the p resence of free radicals. Consequently, premature tissue breakdown can occur. Inevitably, despite our best efforts, our environment will continue to surround us with potentially harmful pollutants. Certainly, there are several things we can do to minimize our health risks, including exercising, eating nutritiously and not smoking. Unfortunately, these measures are rarely enough to substantially decrease our risk of contracting certain degenerative diseases or of getting old before our time. While supplementing our diets with vitamins and minerals is st rongly recommended, certain remarkable, natural substances exist which have recently come to the forefront of scientific research. The most promising of these may be a compound called Pycnogenol, and everyone seems to be talking about it.
Pycnogenol has been associated with:
GREEN COFFEE EXTRACT - Powerful Natural Antioxidant
June 29, 2005 11:06 AM
According to the National Coffee Association’s 2001 National Coffee Drinking Trends survey, 52 percent, or 107 million, U.S. adults drink coffee each day. Although you may already enjoy coffee as your favorite way to begin the morning, new studies are revealing its impressive health benefits. GREEN COFFEE EXTRACT (GCA®) is a newly discovered powerful antioxidant that helps protect against oxidative stress caused by free radicals - a major cause of accelerated aging. Source Naturals GREEN COFFEE EXTRACT (GCA®) is a patent-pending, all-natural green coffee bean extract derived from raw, unroasted coffee beans. It is high in chlorogenic and caffeic acids, two primary compounds responsible for its antioxidant activity. GREEN COFFEE EXTRACT is naturally low in caffeine and contains at least 65 percent total polyphenol antioxidants.
The Coffee Story
The history of coffee dates back more than a thousand years. Originally, coffee beans were used as food. East African tribes would grind the coffee berries together, mixing the results into a paste with animal fat. Later, around 1000 AD, Ethiopians made a type of wine from coffee berries, fermenting the dried beans in water. Coffee also grew naturally on the Arabian Peninsula where it was first developed into a hot drink. Despite decades of research on coffee and caffeine, there are many misconceptions about the potential health risks associated with coffee, while many of the beneficial aspects have gone unnoticed.
Polyphenols: Powerful Antioxidants
Phenolic compounds, or polyphenols, are a widespread family of compounds found in all plants including grapes, coffee and tea. They possess outstanding antioxidant and free radical scavenging properties, which may help defend cells and protect the body against the effects of aging. The high antioxidant activity observed in research on coffee is believed to be mostly due to the phenolic acids. GREEN COFFEE EXTRACT contains a number of polyphenols called hydroxycinnamic acids, with the two most prominent being chlorogenic and caffeic acids. Caffeic acid is the most abundant phenolic compound in coffee. In vitro and in vivo studies show that these acids protect against low-density lipoprotein (LDL) oxidation and lipid peroxidation.
There is accumulating evidence that certain dietary polyphenols, such as chlorogenic acid, may have biological effects in the small intestine that alter patterns of glucose uptake. Chlorogenic acid has been shown to inhibit glucose 6 phosphate (Glc-6-Pase) activity. Glc-6-Pase is an enzyme that has a key role in regulating glucose metabolism. An in vivo study on rats demonstrated that chlorogenic acid improved glucose tolerance.
Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN COFFEE EXTRACT.
Life Force - The Energy Activator
June 29, 2005 10:35 AM
Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100%
We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating.
Bio-Align™ Yourself with Life Force
LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.
Get Ahead with Activated Energy and a Healthy Metabolism
Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.
LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.
Protect Your Heart and Circulatory System
The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.
Skin and Musculoskeletal Support
LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.
Brain and Nerves Nutrition
The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.
LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.
Powerful Liver Support
Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.
Complete Antioxidant Defense
Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.
Cutting-Edge Vision Nutrition
The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.
Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle
LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.
Support Healthy Fat and Protein Consumption with Life Force
Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.
Complete Energizing Nutrition
LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!
RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available
June 24, 2005 05:34 PM
The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.
Bio-Aligned Antioxidant Support
RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.
Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.
Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.
Nourishing the Brain
Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.
Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.
The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.
Skin & Connective Tissue
Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.
Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.
Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.
DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.
Living Longer, Living Better Strategies for Wellness
Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.
Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.
Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf
Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein
Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts
Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric
Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE
Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc
Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf
Composition and Method of increasing Testonsterone...
May 17, 2005 04:01 PM
Composition and method for increasing testosterone levels
Abstract This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites.
May reduce DHT:
By using velvet deer antler along with the testosterone and nor-testosterone precursors, the antler promotes youth film testosterone levels while balancing and ameliorating dangerous spikes in these levels. Another embodiment of the invention includes herbs that inhibits 5-alpha-reductase reducing undesirable levels of dihyrotestosterone. Another embodiment includes chrysin, which inhibits aromatase and the production of estrogenic steroids.
Deer antler (called Rokujo in Ancient Chinese Medicine) is used for its sexual-reinforcing and anti-aging actions. Wang et al., 36(7) CHEM. PHARM. BULL. 2587-92 (1988). Velvet antler is living tissue that grows at a rate of up to 2 cm/day in some species. Cartilage, bone and support tissues such as nerves, blood vessels and hair follicles of the antler also evidence accelerated growth. Antler is the only mammalian organ that regenerates. These features, responsible for the accelerate growth of velvet antler are likely to be caused by either unique regulatory substances or substances found in other tissues but at lower levels. It is believed that factors actually responsible for the rapid regeneration of the velvet antler can explain the powerful health benefits of the product. Specifically, velvet deer antler regulates the adrenal cortex and energy metabolism, promotes sexual function and growth, and strengthens resistance. Its functions fall into the major categories of general body strengthening, healing, promoting blood cell growth and improving immune and cardiovascular function.
Some of velvet deer antler's key ingredients include lysophosphatidyl choline, with hypotensive activity, phosphatidyl ethanolamines, sphingomyelin, phosphatidyl choline hypothanthene and uridene, with monoamine oxidase (MAO)-inhibiting and anti-aging effects; polyamines spermine, spermidine and putrescine, with RNA polymerase stimulating effects; gangliosides that may promote memory and learning; and anti-inflammatory amino acids. A wide variety of growth factors are also found in velvet, and may be associated with its growth-promoting activity. Tsujibo et al., 35(2) CHEM. PHARM. BULL. 654-59 (1987).
As taught by ancient Chinese medicine, deer antler tonifies the yang, primarily deficient yang of the kidneys, spleen and heart. Because kidneys are the seat of the basal yang, the most important use of this class of herbs is to tonify the kidney yang, whose principal manifestation of deficiency is systemic exhaustion. Yang deficiency causes impotence, spermatorrhea, watery vaginal discharge, infertility, enuresis, polyuria, wheezing and daybreak diarrhea. Patients with deficient kidney yang very often have decreased plasma thyroid hormone binding proteins, 24-hour urinary 17-ketosteroids, and decreased rate of glycolysis. When treated with tonifiers such as deer antler, these measurements return to normal ranges. BENSKY ET AL., CHINESE HERBAL MEDICINE, MATERIA MEDICA, REVISED EDITION Eastland Press, Seattle, Wash. (1993).
Deer Antler Velvet Full Spectrum Planetary Formulas 30Ct
Deer Antler Velvet Full Spectrum 60ct