Search Term: " Ascorbic "
Is Apple Juice Acidic or is it Good for Acid Reflux?
July 06, 2017 09:14 AM
Some people might wonder if apple juice is acidic or if it is bad for acid reflux. Apple juice is very delicious and refreshing. It contains good amounts of vitamins and minerals. It is very rich in vitamin C and it provides 159% of the recommended intake. Most of the fruit juices that have an acidic quality have a low PH. For example, the PH of apple juice varies from 3.35 to 4, which is interesting.
"Is apple juice good for acid reflux? No, in fact consuming acidic juices like apple juice may worsen acid reflux."
Read more: http://www.foods4betterhealth.com/is-apple-juice-acidic-35901
Vitamin C breakthrough discovery: Low-cost nutrient halts growth of cancer stem cells... 1000% more effective than cancer drug... peer-reviewed science confirms powerful effects
March 28, 2017 08:59 AM
Researchers have made a remarkable discovery into the potential of vitamin C to stop the growth of cancer cells. This study was performed by the University of Salford and found that vitamin c was ten times more effective than a pharmacy grade cancer drug at stopping a cancerous tumor's ability to process energy to grow. The study is published at Oncotarget and this article provides a link to the study along with more detailed information into the research.
"Vitamin C (ascorbic acid) can be used to target and kill cancer stem cells (CSCs), the cells responsible for fuelling fatal tumours"
Read more: http://www.naturalnews.com/2017-03-22-vitamin-c-breakthrough-discovery-low-cost-nutrient-halts-growth-of-cancer-stem-cells-1000-more-effective-than-cancer-drug-peer-reviewed-science-confirms.html
Mushrooms for nutrition and health
December 31, 2016 02:39 PM
He recommends one tea bag, at least half an hour before you plan to crack open a beer or order wine. This can help, he said, because it has antioxidants that may protect the liver from damage caused by alcohol. "That's my favorite way to support the liver during this time," said Davidson, based in Irvine, Calif. "Help it do its job at a very high level." Some health experts caution that too much green tea can cause damage in rare cases, so don't try to equal your green tea intake with your alcohol.
"Recent investigations have proved the empirical observations of the oriental herbalists that certain mushrooms possess many useful medicinal values."
The Benefits of Vitamin C Related to Skin, Nutrition & Health
December 05, 2016 07:59 AM
Vitamin C is one of many essential nutrients that our bodies require to function properly. The list of benefits of getting the proper amount of this vitamin is quite long. Some of the main effects of vitamin C include stimulating the immune system to avoid illness and help in collagen production to discourage signs of aging and maintain connective tissues. Many foods can have vitamin C artificially added these days, so it’s important to read labels. Foods that naturally provide this wonder-supplement include citrus fruits, green vegetables, strawberries, milk, and potatoes.
"Vitamin C or L-Ascorbic acid or L-ascorbate is an necessary nutrient for humans and certain other animal species, in which it functions as a vitamin."
Does Camu Camu Fruit Have Healing Properties?
April 02, 2014 09:10 PM
What is a camu camu
Inside a rainforest you will discover these types of bushes of which increase within the Rain forest avalanche. The actual fruit obtain from canoes as well as watercraft after that eaten fresh, dried or made into centred fruit juice. Some other part of these berries may be used as well as ingested in various means.
Camu Camu contents and benefits
The actual Camu Camu fruit boosts the manufacturing involving serotonin, the hormone that makes your senses beneficial. The higher level of vitamin G involving any vegetable that helps to improve your entire metabolic rate. There may be exploration evidence of which implies that the fruit features anti-oxidative as well as anti-inflammatory. In addition, it functions as anti-aging method. The actual large antioxidant part of this Camu Camu berry makes a strong compound with healthier skin care solutions. You will discover scientific studies that it has an anti cancer properties. The actual Camu will be adapted straight into makeup as well as healthy skin care because hugely rejuvenative talents.
On the list of crucial ingredients for you to locate a wholesome life is having the necessary every day level of Nutritional G. Nutritional G is surely an Ascorbic p, is normal water-soluble as well as has a critical role inside our each day eating plan. Contrary to almost all mammals, people are not able to by natural means develop Nutritional G consequently, we should acquire the idea inside our eating plan. The actual role of which Nutritional G does eat the body is always to synthesize collagen, and that is a significant structural component of tendons, ligaments, arteries and, as well as navicular bone. Nutritional G is significant since it helps to merge this ingredient component of this neurotransmitter, norepinphrine. Neurotransmitters usually are crucial for you to mind perform. Among other items additionally, it is related to help with our blood cholesterol levels plus the regularity involving gall stones. The word antioxidant goes in conjunction having Nutritional G. Antioxidants are critical within defending one's body coming from harmful free of charge radicals.
The actual deficit involving Nutritional G in every day eating plan have been recognized for countless years for you to result in this generally dangerous illness involving scurvy. Any insufficient Nutritional G is even related to heart conditions. Nutritional G deficit in addition has been assigned to, cerebrovascular event, most cancers, cataracts, and in many cases guide toxicity.
Final thoughts, include the ability from the Camu Camu fresh fruits antioxidant potency for you to fight free of charge radicals as well as re-balance these physiques systems. Combined with the berries, Camu Camu is easily transforming into a recognized super fruit, which includes many reasons as well as prices regarding man well being.
Few reason that tell you why you should consume TMG regularly
January 11, 2014 05:20 PM
TMG or Trimethylglycine
We all know that vitamins and other nutrients are essential for a healthy life and if we lack any of these nutrients or vitamins we consume it by supplement. However, most of us do not know that many other substances are also there that work like vitamins, but they are different from Vitamin and TMG or Trimethylglycine is one of these substances that help your body work effectively.
Benefits of TMG
If we talk about benefits of TMG or Trimethylglycine it is responsible for proper liver functioning, body detoxification, cellular replication, carinitine manufacturing, protection from diabetes and protection of kidney from any kind of damage. Other than this it can also help you to avoid a lot of genetic problems by regulating the genetic transcription process that is responsible for the creation of all the chemicals in body.
In addition to this many researchers also believe it that TMG can improve the autonomous nervous system of body and if it is unbalanced, then it can help you to restore the system. Since TMG is responsible for cell duplication so if someone is facing problem of cell synthesis TMG can help those people as well in restoration of their regular body structure. In short we can say that TMG is one of the most important substances of human body that is very helpful for proper functioning of body in a very effective manner.
Therefore, it is recommended that if you are lacking for TMG you should take it as a dietary supplement so you can increase its count in your body and you can avoid these health problems and you can restore proper functioning of your body. However, it is also very important that you should take the TMG according to specific guideline suggested by your doctor and if you ever find any problem while consuming it, make sure you communicate your doctor about those problems.
Why Zinc is Important for the Body
December 21, 2013 01:39 AM
Zinc is an important trace mineral found in our bodies. Its importance cannot be underestimated for its lack would cause vital body functions to come to a stop.The amount of zinc found in our bodies is about 3 to 4 grams. Zinc is also known to help people escape dangerous diseases like acne, Alzheimer's and many others. Below is a brief account of the various vital functions of zinc:
Zinc enables vital body functions to occur.This is because it stimulates over a 100 enzymes in the body. Enzymes are known to aid in body processes including such activities as making vital body components or helping break down chemicals that the body does not need or would rather harm it, if left to accumulate. Still in enzymatic functions, zinc plays a role in the formation of DNA, bones and breakdown of the proteins we eat.
Zinc is very vital when it comes to protecting our bodies against infections. It achieves this function in a multiplicity of ways, the very first being the pivotal role it plays in the healing of wounds. Zinc is also found in body secretions that kill bacteria and viruses which may find their way into our bodies. This is made possible by the fact that it has anti-microbial effects.
Zinc is also known to assist in protecting our cell membranes from the harmful effects of metals such as copper and iron. Another similar function of zinc is its ability to assist the liver form an antioxidant known as super-peroxide that assists in elimination of harmful toxins that would otherwise harm the body. Zinc will also help reduce poor night vision for it will slow ocular degeneration.
Boost Energy With CoQ10 And L-Carnitine
November 21, 2013 08:43 PM
CoQ10 and L-Carnatine
CoQ10 and L-Carnitine offer double protection for the heart and the brain in just a single tablet. You obtain all benefits for your heart at 100% from CoQ10, while L-Carnitine supports your memory, learning ability, and focus. The exclusive combination of CoenzymeQ10 and L-Carnitine encloses an absorbable, water soluble capsule of CoQ10 and L-Carnitine, which is important for proper usage.Why are CoQ10 and L-Carnitine Supportive in Energy Boost?
CoQ10 Energy Boost
CoQ10 is a vital nutritional element found in all body cells, in particular the mitochondria, in which most energy is generated. The major function of this coenzyme is to assist in the process of oxygen and food conversion into energy. As people grow older their ability to naturally, to produce this coenzyme decays.
At the same time as Coenzyme Q10 is taking part in the production of energy in each cell of your body, it is considered be remarkably imperative for the high energy requirements of the heart. The heart needs vast energy amounts, because it is the hardest worker in your entire body. Coenzyme Q10 seems to be indispensable for this process. It offers you sufficient antioxidant provision, protecting the body cells from damage of the free radicals, and proffering a dynamic function of the immune system.
L-Carnitine Energy Boost
L-Carnitine transports indispensable fat acids into the same organ where CoQ10 plays its major function - the mitochondria. There, with the help of L-Carnitine, all fatty acids are turned into energy. However, the beneficial function of L-Carnitine does not end here. In addition, it also supports the transportation of toxins outside the body. You can think of the problems that might occur if these vital body processes are not fully operational. At the same time however, the major impact of L-Carnitine over the body is directed towards the brain:
What Makes Tupelo Honey The Best Form Of Honey To Consume?
January 02, 2013 11:48 AM
The Reason Why Tupelo Honey Is The Best!
The delicious sweet honey brings water to everyone's mouth. It is available in various forms to the honey lovers in different tastes. Often the classification is on different criteria. One such classification is based on the sources from which the honey is collected and another type of classification is based on the way in which the honey is processed and packaged.
Tupelo honey forms a part of the first type of classification.
There are many other types apart from this, all of which differ in tastes besides producing various benefits. However tupelo honey has better edge over others which can be substantiated with the following explanation. Tupelo honey is made from Nyssa Ogecha, the white tupelo tree. This is found mainly in the south eastern region of the United States. The basin of the Apalachicola River is the main source for this honey. The basins of other rivers such as Ochlocknee, Chipola and Choctahatchee also contain some trees that produce tupelo honey.
Tupelo Honey Nutrient Rich!
Often it is considered as the best form of honey because of its high ratio of the level of fructose to that of glucose. This indicates that it is capable of generating energy for the body for a longer duration than other forms of honey, besides containing all the antibacterial and antimicrobial properties like other forms of honey. Tupelo honey is rich in nutritional composition with dextrose accounting for 25.29 percent, fructose for 43.25 percent, sucrose for 1.21 percent, maltose for 7.97 and other the higher sugars for 1.1 percent.
In addition to these, it also contains riboflavin, thiamine, nicotinic acid, Ascorbic acid, sodium, magnesium, potassium, manganese, copper, iron, phosphorous and calcium. Hence this is used for curing cough problems, treating sore throats and burns. Also because of its low level of dextrose and high level of fructose, its usage is often recommended for diabetics patients.
Amla Fruit Extract
November 08, 2012 05:04 PM
Amla fruit is a plum size fruit that grows from a small, strong, lemon scented leafy bush usually referred to as gooseberry fruit or Amalaki. amla extract is a good natural source of heat stable form of vitamin C which is not easily broken by heat as well as Proteins,fiber and other minerals like antioxidant chemicals such as Quercetin, Gallic ,Ellargic acids and Corilagin.These particular minerals and chemical components are usually beneficial to human health matters as they proves to be antioxidants, therefore able to neutralize the cell damaging free radicals and to ensure the elimination of heart problems,cancer and reduction in the ageing process not to mention the death of body cells.
Amla contains Ascorbic acid or Vitamin c in abundance where this mineral is quite beneficial to the body mainly when taken raw. These particular mineral of vitamin c offers to reduce the colds, acting as natural histamine and to boost the immunity system of the body.On the other hand amla is used as a herbal medicine for digestive problems,remedies for cardiac issues,to strengthen immune system as well as to improve an individuals eyesight.
The amla extract consists of a complex make up that contains mineral rich amino acids, a balm proven to be helpful as a natural hair conditioner giving the hair stronger hair follicles and scalp reducing greying,breakages and on the other hand it has antiseptic and astringent properties to tone the scalp and prevent scalp infections as well as to enrich the colour through pigment production resulting in rich thicker and healthier hair.
Other benefits of amla fruit extract is its anti-inflammatory effect a property that prevails against the hay fever that causes the inflammation of the eyes and nose and on the other hand reducing inflammatory caused by joint pain and arthritis as well.When one eats this high fiber content amla fruit it would help him or her to have control of the his bowel movements and hence ease constipation whereas blocking aldose reluctase hence preventing cataract in diabetics on the other hand amla which can effectively act as sedatives reduces stress,improving a persons sleep as well as to relax the muscle.
Glutathion, Antioxidants, And The Body
July 14, 2010 02:41 PM
Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, cysteine, and glycine. Due to the chemical nature of sulphur-containing cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges.
Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis.
A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids.
The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell.
Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion.
Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and Ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well.
Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.
May 22, 2009 11:44 AM
Bitter melon, which is also referred to as bitter gourd, is the fruit of the Momordica charantia plant. This plant is a climbing vine that originated in Asia, Africa, and Australia. Now, it is grown in warm climates all over the world. The fruit is one of the bitterest fruits of all plant foods. The oblong shaped bitter melon has warty appearance, making it quite easy to distinguish. The bitter melon fruit is hollow in cross-section with a thin layer of flesh that surrounds the central seed cavity. This cavity is filled with large flat seeds and pith which appear white in unripe fruits and red in those that are ripe.
The seeds and pith are not intensely bitter and can be removed before cooking. The pith will become sweet when the fruit is fully ripe. The pith can be eaten uncooked in this state, but the flesh is far too tough to be eaten anymore. The flesh of this fruit is crunchy and watery in texture, similar to that of cucumber, chayote, or a green bell pepper. The skin is tender and edible. Most often, the fruit is often eaten green, but it can be eaten when it has started to ripen and turn yellowish. However, it grows more bitter as it ripens.
Bitter melon has a history of being used in fold medicine all over the world. It is though to be natural insulin in Ayurvedic tradition, making it highly recommended for the treatment of diabetes. Bitter melon is also one of the main components of the Okinawa diet. These people have the highest percentage of centenarians in the world, the longest healthy life expectancy, and a very low incidence of heart disease. This fruit has often been used for the treatment of tumors, asthma, skin infections, gastrointestinal ailments, and high blood pressure. Bitter melon has been a traditional remedy in Africa, China, India, and the southeastern portion of the United States.
Currently, bitter melon is being researched as a remedy for diabetes, AIDS, and some kinds of cancer. It can be used to help regulate blood sugar by reducing blood glucose and improving glucose tolerance. However, no studies have established a safe and effective dose. The plant’s roots and leaf extracts have shown antibiotic properties. Some studies suggest the possibility that an element in bitter melon may prevent the HIV virus from infecting human cells. Laboratory research shows that one component of the plant may even help to inhibit the growth of some cancers. In some studies, those people who take bitter melon developed headaches. It should be noted that expectant mothers should not use bitter melon.
The fruit, leaves, seeds, and seed oil of the bitter melon fruit are used to provide abortifacient, antifertility, antimicrobial, and hypoglycemia properties. The primary nutrients found in this fruit are Ascorbic acid, glycosides, iron, niacin, riboflavin, sodium, and thiamine. Primarily, the bitter melon fruit is extremely beneficial in treating asthma, cancer, diabetes, gastrointestinal issues, HIV/AIDS, hypertension, skin infections, and tumors.
Bitter melon is available in capsule or tablet forms at your local or internet health food store. For more information on the beneficial effects provided by the bitter melon fruit, please contact a representative from your local health food store. *Statements contained herein have not been evaluated by the Food and Drug Administration. Bitter melon and magnesium is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
BerryOxidants - Food-Sourced Antioxidant Protection
April 12, 2009 11:07 AM
BerryOxidants - Food-Sourced Antioxidant Protection
2 tablets contain:
Vitamin C (as Ascorbic acid) 1,000 mg
Grape Seed Extract (Proanthodyn™) 150 mg
Green Tea Leaf Ext (95% polyphenols, 150 mg 35% ECGC)
Turmeric Rhizome Ext (95% curcumin) 150 mg
Polygonum cuspidatum Root Ex 100 mg (8% total resveratrols)
Bromelain 100 mg
Quercetin 100 mg
Ginkgo Leaf Extract (50:1) 60 mg
Silymarin (from milk thistle seed ext) 60 mg
Hawthorn Berry Extract (4:1) 50 mg
Rosemary Leaf Extract (5:1) 50 mg
Citrus Bioflavonoids 50 mg
Lecithin 50 mg
Grape Skin Extract (20% polyphenols) 50 mg
Astragalus Root Extract (10:1) 50 mg
Cabbage Floret & Stem 50 mg
Cranberry Fruit Ext (90% solids) 50 mg
Sweet Cherry Fruit Ext (10:1) 50 mg
Holy Basil Leaf Ext (2% ursolic acid) 50 mg
Olive Leaf Ext (15% oleuropein) 40 mg
Rutin 40 mg
Lycium Fruit Extract (4:1) 40 mg
Strawberry Fruit 40 mg
Açai Fruit Juice Powder 40 mg
Organic Amla Fruit 40 mg
Pomegranate Seed Ext (40% elagitannins) 20 mg
European Elder Berry Ext (5% flavones) 20 mg
Mangosteen Fruit Rind Extract 20 mg (standardized to 95% flavonoids & 40% mangostins)
Raspberry Leaf Ext (40% elagitannins) 10 mg
White Mulberry Fruit Ext (10:1) 10 mg
Blueberry Leaf Ext (20% chlorogenic acid) 10 mg
Bilberry Fruit Ext (25% anthocyanidins) 5 mg
Supports Healthy Blood Pressure
April 18, 2008 03:59 PM
3 tablets contain:
Suggested Use: 3 tablets mid-morning and 2 tabs mid-afternoon between meals on an empty stomach.
The Benefits of Ascorbyl Palmitate A Fat-Soluble Form of Ascorbic Acid
February 09, 2008 10:43 AM
The benefits of ascorbyl palmitate are due to the substance being a fat-soluble form of Ascorbic acid which is otherwise known as vitamin C. Before discussing why being fat-soluble should be of benefit, let us first have a look at what vitamin C does for us and what its limitations are.
Most people know vitamin C as the vitamin that prevents us from getting scurvy, and that limes and other citrus fruits were given to sailors to prevent them from contracting this often fatal disease on long journeys. However, important though the protection it provides against scurvy is, there are many more important uses for this important vitamin. In fact some of them are closely connected to the symptoms of scurvy.
Among these are pains and swelling in the joints, and the loosening of teeth and hair loss. Scurvy is also associated with easy bruising and bleeding. All of these can be associated with loss of collagen, which is contained in connective tissues, bone and blood vessels. Collagen repairs and maintains cartilage, heals wounds and is essential for proper skin formation and the structure of ligaments, tendons, blood vessels, bones, hair and teeth. When we consider that one of the most important properties of vitamin C is the part it plays in the production of collagen in the body, then its effectiveness in alleviating the symptoms of scurvy is not difficult to understand.
Vitamin C is also a strong antioxidant that destroys free radicals that kill and severely damage body cells, and cause a large variety of undesirable conditions such as atherosclerosis and cancers, and also debilitating and painful inflammatory conditions such as arthritis. Many free radicals are formed in the body as by-products of our metabolism: the generation of energy from fats and blood glucose. Others are ingested in the form of cigarette smoke and other toxins, while yet other free radicals are caused by the effect of sunlight on our skins. Natural antioxidants such as vitamins A, C and E help to keep these free radicals under control and minimize their effect.
Another interesting property of vitamin C is in the synthesis of carnetine, a deficiency of which is also thought to contribute to scurvy. Carnetine is needed by the body to transport fat to the cellular mitochondria so that it can be converted to energy. Vitamin C is also believed to take part in the biochemistry that converts cholesterol to bile acids and so helps to maintain a healthy level of cholesterol in the blood.
The vitamin is therefore a very useful one for the body, but it has one fault. It is water soluble, and hence cannot be stored in the body but is expelled in the urine. Had it been fat soluble it could have been able to be stored in the body fats, in the same way that vitamins A and E are, and be available for use when required. Instead any excess that is not immediately used is lost, and a fresh intake of Ascorbic acid necessary on a continuous basis.
Not only that, but it is only of use in areas of the body that the blood can reach. Fatty tissue is practically devoid of vitamin C, and many areas of the brain cannot be reached by substances that are insoluble in oils and fats. It also finds it difficult to penetrate the skin and the walls of body cells. This is where the benefits of ascorbyl palmitate are useful.
Ascorbyl palmitate is a fat-soluble form of vitamin C and possesses all of the attributes of Ascorbic acid. It is more easily absorbed by the body and can be stored in the membranes of the cells until needed. It is also a powerful antioxidant, the same as vitamin C, and is frequently used to prevent the oxidation of vegetables oils, such as on potato chips and other oily snacks. It also takes part in the biochemistry of the production of collagen and connective tissues.
The usefulness of this substance comes from not only from its amphoteric nature, whereby it has one end that is water soluble and another that is fat soluble, but also by the fact that it is also amphipathic, meaning that it prefers neither one medium nor the other, and tends to collect at phase boundaries, between oil and water phases. It is particularly effective in topical uses on the skin, because it is easily absorbed into the skin tissue, and more stable than some of the other forms of vitamin C. It is also believed to protect other fat soluble antioxidants such as vitamin E from oxidation, and also to help to protect blood cell membranes from free radical attack.
Although vitamin C is a very powerful vitamin, carrying out a multitude of tasks, ascorbyl palmitate has some advantages over it apart from the solubility difference. Its antioxidant properties are stronger than those of regular Ascorbic acid and in fact rival those even of vitamin E, which it also helps to regenerate after its reaction with free radicals, and help to maintain a continuous supply of this powerful antioxidant.
It is also a chemically neutral form of the vitamin, and unlike regular Ascorbic acid, does not cause inflammation of the tissues it comes into contact with. It can also reduce sunburn due to excessive exposure to UVB when applied to the skin, and is a very stable form of the vitamin. Ascorbyl palmitate also acts as an anti-inflammatory with certain conditions, such as psoriasis where topical application helped to reduce the extent of the lesions. In fact it appears to do most of what vitamin C does, but faster and with smaller doses.
So why is ascorbyl palmitate not used as the main form of vitamin C in supplements? The answer is money. Ascorbyl palmitate is considerably more expensive than regular vitamin C, and also normal Ascorbic acid has some properties that the fat-soluble form does not have, such as its ability to rapidly pass through the body in the bloodstream.
However, it would make sense to take a supplement consisting of both forms of vitamin C, and so combine the best properties of each. Any vitamin C supplement that is designed for maximum effect on the body should contain at least 25% of ascorbyl palmitate, the balance being Ascorbic acid. That is what to look for if you are to receive the combined benefits of both water and fat soluble vitamin C.
Goji Berry Elixir Antioxidant Rich Tonic
January 26, 2008 08:25 AM
• Nutrient-rich goji extract
• Renowned longevity tonic from China
• Provides powerful antioxidant protection
• Helps maintain visual acuity
Goji is highly revered as a general health-promoting longevity tonic and has been used in Chinese herbalism for thousands of years. The antioxidants in Goji Berry Elixir support cholesterol wellness, healthy circulation and normal cellular metabolism. The addition of seven additional fruit concentrates enhances the many health benefits which goji provides. Planetary Herbals Goji Berry Elixir™ is a highly concentrated source of goji (Lycium barbarum) which is rich in polyphenols, carotenoids and other antioxidants.
1 fl oz contains:
Vitamin C (as Ascorbic acid) 60 mg
Proprietary Goji Fruit Blend: 15 g
Goji Berry Concentrate, Apple Concentrate, White Grape Concentrate, Pear Concentrate, Cranberry Concentrate, Elderberry Concentrate, Grape Seed Extract.
Suggested Use: 1 ounce twice daily.
Chronic Illness and eating healthy
November 09, 2007 12:43 PM
Chronic illness which exhibits itself as a recurring disease, with lingering and lasting symptoms is a growing pandemic amongst people today. The question is how much of this is due to neglect on the basics of healthy living? Today’s fast paced life style could be a factor for these reoccurring problems. For example, we pride ourselves on keeping five things in the air at the same time; this has caused us to slip from eating three healthy meals per day to drinking a slim fast or popping a diet pill to keep going. Moving away from proper diet and nutrition may be the reason our bodies are breaking down today resulting in chronic illnesses.
Whether you are free from or burdened by illness it is time to take charge of your health! The first thing one can do is basic research. Studies on dietary supplements in scientific and medical research are an ongoing process both in the United States and internationally. If you are interested in finding citations on a particular chronic illness or research that is available I recommend looking at government agencies such as (i) The Office of Dietary Supplements, (ii) The National Institutes of Health (NIH), (iii) The National Agricultural Library (NAL), and (iv) United States Department of agriculture (USDA). It is also possible to obtain research abstracts from different major databases such as MEDLINE for biomedical related articles and AGRICOLA for botanical and agricultural science. To find these different databases and governmental agencies, search google using the respective agency/database name.
Research shows that stress reduction can help to improve energy levels, improve sleep quality, and reduce high blood pressure. The following are some suggestions for reducing stress:
1. Weight lifting is not just about barbells and muscle-building but about stressing the body as a means for relieving stress.
2. Cardiovascular exercises such as jogging and bicycling.
3. Exercise is helpful by increasing blood flow to the brain, release of hormones, stimulates the nervous system and produces a feeling of well being.
Eating healthy including supplementation
1. Vitamin C or Ascorbic acid has the ability to boost the immune system. Vitamin C also helps to produce neurotransmitters by converting L-Tyrosine into dopamine. Along with dopamine, Ascorbic acid also synthesizes norepinephrine and serotonin which have been found to be directly related to control anxiety and depression.
2. B-Vitamins are also the important for reducing stress. For example, Niacin (Vitamin B3) helps the body fight stress in three ways, (i) controls blood sugars, (ii) improves blood flow and (iii) regulates the release of energy from carbohydrates.
Stress is a state of bodily or mental tension resulting from factors which are an unavoidable effect of living. Stress has been linked to coronary heart disease, psychosomatic disorders and various other mental and physical problems. Reducing stress is essential and can be done through diet and exercise. Nutritional science studies the relationship between diet and states of health and disease. Nutritional science has found human nutrition is very complex and varies widely and proper nutrition cannot be obtained by simply eating three meals a day because quite simply the average person just does not eat well. If you eat less than five servings of fruits and vegetables daily it is impossible to obtain all of the vitamins and minerals your body needs. In order to seek assurance that you are getting all your body needs I suggest you take a good multiple vitamins which supplies at least 100 percent of the daily value for various vitamins and minerals. It is a good idea however to discuss with your doctor the best choices as he or she knows your history and specific health needs best.
Triphala: A Traditional Ayurvedic Herb to Help Cleanse the Body
November 01, 2007 01:44 PM
Triphala is a traditional Indian ayurvedic remedy, that, as the name suggests, is actually composed of three different herbs or fruits. However, before describing the constituents, first an explanation of what ayurveda is and what it does.
Ayurveda is a science that is centuries old, and has been in use for at least five thousand years. Originating in prehistoric India, it is based upon the approach it takes in that all ills are caused by anomalies of the digestive system. All that exists on earth is believed to be composed of five elements (the pancha mahabhooota): earth (prithyi), fire (agni), water (jal), air (yayu) and ether (akash). The latter can be approximately described as space
Ayurveda combines these into three main doshas: Vata, a combination of the ether are air elements, Pitta, which is the same as the fire element, and Kapha that is a combination of the earth and water elements). Each of these has specific effects on the body, and when in equilibrium then the body is also in equilibrium.
Vata governs what is loosely described as movement in both the mind and body. An excess of vata leads to worries, anxiety, constipation and cramps of the stomach. It is responsible for waste elimination, flow of the blood, breathing and even movement of thought. Everything connected with movement in the body. It is believed to be expressed visibly and audibly as creativity and art and is believed also to be the initial cause of all disease and illness.
Pitta, the fire dosha, governs the metabolism and body heat. It is responsible for the way we digest our food and how we know right from wrong. An excess of pitta causes anger, ulcers, dyspepsia and criticism. If your pitta is balanced you are a good friend and warm personality.
Kapha provides and maintains the physical elements of the body, such as good joints, healing of wounds and strength. It maintains a strong heart and lungs, and everything physical. It promotes love and forgiveness, but also envy and greed. Too much in an individual causes lethargy, allergies, congestion and weight gain. It is also called the mucus humor.
The three fruits of triphala are amalaki, bhibitaki and haritaki, and together maintain these three doshas in balance. Amalaki, or amla, is used to treat an imbalance in the pitta, or fire humor. It is sour and is exceptionally rich in vitamin C and is therefore a strong anti-oxidant. It is the highest natural source of this vitamin. It is used as a tonic, for boosting the immune system and for its anti-aging properties. It is also a good adaptogen and has strong stomach acid neutralizing effects. It is therefore effective in reducing dyspepsia and in the treatment of gastric ulcers, and also possesses cholesterol-reducing properties. Amalaki provides the body with strength and is used in the treatment of disorders of the respiratory tract and any illness that creates burning sensations.
Bhibitaki, or bihara, is also useful in the treatment of respiratory disorders, and has a number of effects that are useful in treating digestive disorder. It deals with problems associated with the kapha or mucus humor. Thus, it possesses anti-mucal, laxative, astringent, digestive and anti-spasmodic properties, and is also a tonic and an expectorant and helps deal with allergies.
Haritaki, or haradaha, deals with diseases of the vata humor. It is very bitter with a strong antimicrobial and laxative effect on the digestive system, and is a rejuvenator that promotes long life and boosts the immune system of the body (though the scientific effect was unknown to the ancient exponents of ayurveda). It also possesses an astringent and lubricant effect and used to treat constipation, anxiety and stress.
When combined into triphala, the products are a popular treatment for all digestive disorders and is popularly used to cleanse the colon. It aids digestion, improves the metabolic processes involved and also aids abdominal pains, flatulence and eases conditions of the liver. It is useful in the treatment of what today are termed ulcerative colitis and irritable bowel syndrome. The ancient Indians were able to treat these conditions of the digestive systems without understanding what they were and what caused them.
Triphala is also widely used in the treatment of conjunctivitis and prevention of atherosclerosis. This is likely due to its antioxidant effect and the high level of Ascorbic acid it contains. Its anti-inflammatory properties are also likely derived from the same source. These properties, and its effects as a tonic and cleanser, render it a popular treatment for many skin conditions. It is a multi-purpose treatment for a multitude of illnesses and conditions and has been used effectively for thousands of years.
Modern science has provided an explanation for most of these effects. Many of the conditions that triphala is effective in treating have been shown to be caused by excessive blood cholesterol and lipid levels. Many can be attributed to circulatory disorders caused by cholesterol build up in the arteries, or atherosclerosis. Some of the benefits of the three fruits are associated with the lowering of cholesterol and of blood pressure that benefits circulation.
Cholesterol build up and internal stress is associated with the consumption of hot spicy foods, the use of excessive stimulants and repression of the natural emotions. The way the body handles these is to produce corticosteroids that can contribute to cholesterol build up in the blood. Triphala can be used to reduce blood LDL cholesterol and increase the HDL lipoprotein that eliminates cholesterol from the body. Amla fruit has been shown to reduce serum and aortic cholesterol, and also increase cardiac glycogen that provides an energy source for the heart that can help prevent cardiac disease.
Bihara contains 35% oil of which 31% is linoleic that increases the good HDL cholesterol and reduces the bad LDL cholesterol. Harada has been found to reduce blood pressure and intestinal spasms, thus backing up its use for treating heart and intestinal conditions.
Triphala is a traditional ayurvedic herb that has many uses in cleansing the body that have been investigated and backed up by modern medical science. The mixture of the three fruits have strong anti-oxidant, anti-spasmodic and cholesterol reducing effects, and also possess laxative properties that can ease a large number of different physical and psychological health problems.
Prevent Disease With Discount Vitamins
October 24, 2007 09:33 AM
You can prevent disease with discount vitamin just as easy as with those you pay top dollar for on the High Street. Vitamins are vitamins, and they do not lose quality for price as long as you know what to look for and stick with name brands. They are the most purchased supplement in the western world, and there are ways of getting them for less than the normal price.
First, though, a definition of what a vitamin is since an astounding number of people have no idea of what actually constitutes a vitamin even though they can recite all the letters. In fact, a vitamin is a molecule, obtained from an organic animal or vegetable source that is essential for life. Without it there can be no animal life and vitamins generally catalyze or act as coenzymes in the biochemistry that makes up all of the chemical reactions of the body. A catalyst allows a reaction to occur without changing itself, and a coenzyme allows enzymes to do their jobs.
Let’s have a look at one or two vitamins to provide examples of these statements. In bygone days when sailors used sail to cross the oceans in open boats powered only by sail and oar, a trip that takes us a week in a cruise liner these days could take sailors several months. It was not only the fact that they relied on favorable winds, but also that they did not always know where they were going, and were frequently unable to store up for a whole voyage. They depended on landing at islands on the way to replenish supplies. Disease due to lack of nutrition was common and one of these was scurvy.
This condition is not strictly a disease and is due to a lack of vitamin C, or Ascorbic acid. In fact the name ‘Ascorbic’ comes from the Latin for ‘without scurvy’. The symptoms are liverish spots over the body, spongy gums that cause the teeth to fall out and bleeding from the mucus membranes. Healed scars will open up, and cured and knitted bone fractures will separate. Ultimately it causes death. The first person is used since scurvy still exists.
It is due to a breakdown in the synthesis of collagen which heals scars, keeps joints held together, and forms the outside part of cells, and also some inner cell structures. Collagen synthesis is dependent on the amino acids proline and lysine that are hydroxylated by the enzymes lysyl and prolyl hydroxylase. The problem is that these enzymes need Ascorbic acid (vitamin C) to do their work. Without it, collagen cannot be made.
Although the chemistry was unknown, early sailors soon found that citrus fruits such as lemons and limes prevented this horrible condition. The English used to stock up their ships with fresh limes at any port of call that had them, and this is why the English are frequently referred to a ‘Limeys’. It got them a nickname, but it saved their lives. Scurvy is now rare, but it is not a disease as such that can be eradicated. It occurs now and again in teenagers with poor diets that do not include fresh fruit and vegetables.
Vitamin C supplements are now available, and it is one of the most common of the discount vitamins on the market. The same is true of vitamin A that is essential for good eyesight. It has many other uses, as has vitamin C, but without it we could not survive. Without it we will eventually become blind, although the first symptom is night blindness. However, an excess can lead to hypovitaminosis A, a condition common in the developed world. Its absence can kill us, and vitamin A deficiency is one of the more common conditions of the developing world. Vitamins are contrary creatures, and can do us harm as well as good.
How about vitamin D, the sunlight vitamin? We don’t think of it, yet it is responsible for the strength of your skeleton and the regulation of calcium and phosphorus levels in the blood. Without it our bones become soft, our children get rickets and we eventually die – frequently through cancer.
1,25-dihydroxycholecalciferol is the chemical name for calcitriol, which is the form of vitamin D found in the body, known as vitamin D3. This has been found to kill some cancer cells in the laboratory, and it is thought that supplements of vitamin D might help to prevent some types of cancer. The reults of a four year cancer study were released in June, 2007, that showed a reduction of 60% in cancers where patients were given a aupplement of 1100 inernational units daily. This rose to 77% where the cancers had been diagnosed in their first year.
The effect of vitamin D was emphasized by the reults of a study of more than 4 million cancer patients that showed a marked difference in the risk of cancer according to whether they lived in sunny or less sunny climates.
So these are the benefits of some discount vitamin supplements. How, then, do you find vitamins at discount prices? The easiest way is to purchase in bulk. There are those that form online clubs for vitamins and pay a weekly or monthly fee to join. When offers come online for specific supplements at low prices, they are purchased by the groups and distributed. You could do the same yourself with some friends, since it is generally cheaper to purchase 5 Kg of a vitamin that 500g. Your local health food store could also help you out since they are likely to be able to procure discount bulk prices from their supplier.
Another way is to wait until your local store makes special offers, or seek offers in the press. These can often be found, but if you are concerned mainly with the common vitamins A, B complex, C, D and E then a large proportion of the population are interested in these and you should not find it difficult to sell several kilos of these. You will not only get yours free, but will a sizeable profit into the bargain.
Anything between that and the normal price is an advantage for chemicals that are essential for life. One thing to always remember, buy reputable name brand vitamins because if the vitamins seem to cheap than you’re probably right. Name brand vitamins have quality and can be purchased at discount prices if you look long enough.
Vitamin C Citations
May 28, 2007 11:49 AM
What is it? The world’s best known water-soluble antioxidant vitamin; also known as Ascorbic acid.
What does it do? Has aided anti-cancer therapy when used intravenously (under a practitioner’s supervision); ingestion of more commonly available dosages has been linked with both reduced cancer risk and lower risk of death from all causes.
The Fizzy Comparison (Airborne Vs Wellness Fizz)
February 26, 2007 03:02 PM
The Fizzy Comparison
(Lonicera, Forsythia, Schizonepeta, Ginger, Chinese Vitex, IsatisRoot, Echinacea)
(L-Glutamine, L-Lysine HCL)
Also Contains: Sorbitol, Mineral Oil, Sucraloseand Acesulfamepotassium (artificial sweetener)
Wellness Fizz Ingredients
Vitamin A (as beta carotene) 5000 I.U.
(Forsythia, Japanese honeysuckle, Platycodon, Chinese Mint, Lophatherum, Chinese Licorice, Schizonepeta, Soy bean, Burdock, Phragmites)
Also Contains:Stevialeaf, natural flavors, honey
Wellness Fizz - Fast-Acting Immune Defense
February 26, 2007 02:15 PM
Dr. Nugent’s Genetic Key Diet Notes Why is America Losing the Fat Battle?
September 19, 2006 05:48 PM
MSG Factor: increases appetite, triggers something in your body that makes you want more. There are no genetically fat rats but they make them fat by giving them MSG. they have taken an animal that has no natural obese traits or genetics and “enhanced” them. MSG is a flavoring that makes you want to eat more. The phrase “Betch ya cant eat just one!” has true meaning! It is in highly processed foods under different labeling names so that we purposely don’t see the words MSG (Monosodium Glutamate.)
Most tenderizers are high in MSG, “accent” and “adolph’s” are among the list. your fast food restaurants’ are guilty as well. It’s what keeps you coming back and eating far more than you should need.
“Packages that say no MSG is because they are now putting tow preservatives that combine together to make MSG. Ascorbic Acid (preservative), and benzene salts combine to make MSG when heated. Soft drinks are stored in hot ware0houses, transported in hot trucks, and cans heat to over 100 degrees. Soft drinks do not have MSG added, but end up with it.”
Ascorbic acid and benzoate salt are preservatives that are combined in soft drinks and boxed fruit juices. When the drinks are exposed to heat and light the combination can stimulate the formation of benzene. We all know from reading Dr. Nugent’s Toxic Planet book that benzene is highly toxic in levels far below what the EPA states as safe. Considering that a lot of people live in warm, even hot states, the distribution centers and trucks are not kept cool, these drinks are heated in transport and storage. The soft drinks can end up with low levels of benzene. Your body doesn’t have the need, desire or tolerance for benzene at any level! If there ever was a good reason to get off soda and boxed drinks! Think about it.
Have you ever eaten to much at a nice restaurant, maybe a buffet and you must clean up your plate. The next day, you’re starving! Could be the MSG hangover.
Our brain needs 10 teaspoons of glucose each day for normal function. Because people have been warned about the problems with sugar we have added the pink, yellow & blue packets. Worse.
I stood in line behind a woman buying a small sack of prescriptions with a big price tag. She said its very expensive to be sick. (And she had a bottle of diet soda to go along with it.)
My husband said one time, “well, sooner or later we’re all going to get something and die.” I answered – “No-o-o, sooner or later we’re all going to die, but we don’t have to get sick.”
I used to subscribe to prevention magazine. After seeing so many advertisements for drugs, I dropped it. What is there in prevention that could cause me to take a drug?
Try Glyconutrients instead.
Soft Drinks Contaminated by Benzene
May 27, 2006 09:24 AM
A Food and Drug Administration (FDA) testing program has found cancer-causing benzene in soft drinks at levels averaging four times the standard for tap water. The brand names have not been released.
The test data were uncovered by the Environmental Working Group (EWG), which posted the test results on the group’s website, www.ewg.org
Highly elevated Benzene Levels
Between 1995-2001 the RDA tested 24 samples of diet soda for benzene. The result: 79% tested at levels above the federal limit for benzene in tap water, which is 5 parts per billion (ppb). The maximum benzene level detected was 55 ppb. In addition to the diet sodas, the FDA tested a number of other non-diet soft drinks. One cola was contaminated at 27 times the tap water limit, and fruit drink had a 95 ppb level.
“These results confirm our suspicions there are highly elevated benzene levels in some very popular drinks,” Richard Wiles, EWG’s senior vice president said in a press release.
Reaction Triggered by Preservatives
According to an article in beveragedaily.com, sodium benzoate and Ascorbic acid in soft drinks can react together to form benzene. Sodium benzoate is a common preservative in soft drinks, and Ascorbic acid is often added as an antioxidant to extend shelf life.
Negotiations between the FDA and the beverage industry in 1990 resulted in an agreement that the industry would voluntarily reformulate its soft drinks to prevent this combination. The recurrence of benzene contamination may be due to new soft drink manufacturers in the market who were not a part of, or aware of, the original negotiations.
Britain Pulls Soft Drinks from Shelves
In contrast to the U.S. situation, food safety campaigners in England were successful in having benzene –containing soft drinks removed from the supermarket shelves. The British Food Standards Agency pulled four soft drink brands which contained more than 1 ppb of benzene, and rushed out the results of tests on 149 drinks, including a range of fruit juice, iced tea, squash, fizzy and low-sugar drinks, according to The Times of London.
The Wellness Revolution and Contaminated Soft Drinks
The controversy over benzene in soft drinks is an example of how toxic exposure exists in our food and immediate environment. The constant exposure to toxics were-and especially our children—experience is a major cause of chronic illness.
In this situation, the organic products available for purchase in health food stores are especially vital. And since some exposure to toxics is unavoidable we must take advantage of the herbs and nutrients that support detoxification and the liver, the main organ of detoxification, as well as immunity for example, silymarin, N-acetyl cysteine, calcium D-glucarate, folic acid, Reishi and shiitake mushrooms, and turmeric.
Sources: www.ewg.org www.beveragedaily.com 02/25/06. Associated Press 04/11/06. www.fda.org.
Public Pressure Forces Corporations to Curtail Most Soda Pop sales to schools
The Nation’s largest beverage distributors have agreed to halt nearly all soda sales to public schools, according to a deal announced may 3rd by the William J. Clinton Foundation.
The companies have agreed to sell only water, unsweetened juice and low fat milks to elementary and middle schools, according to a spokesman for former President Bill Clinton. Diet sodas would be sold only to high schools.
The deal follows a wave of criticism by school districts and state legislatures amid reports of rising childhood obesity. Soda has been a particular target because of its caloric content and popularity among children.
HDL Booster - Boost your good cholesterol
March 16, 2006 12:51 PM
(Product No. 02922)
HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*
· Formulated by Dr. Dennis Goodman, Chief of Cardiology at
· Clinically studied to increase good cholesterol levels up to 23%*1
· All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association
· Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2
HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*
Two tablets (one serving) contain:
Vitamin C (Ascorbic acid) 148 mg
Vitamin E (as natural mixed tocopherols) 35 IU
Niacin (as niacinamide) 21 mg
Vitamin B6 (as pyridoxine HCl) 3 mg
Folic Acid 301 mcg
Vitamin B12 (as cyanocobalamin) 20 mcg
Magnesium (from magnesium amino acid chelate) 10 mg
Selenium (as L-selenomethionine) 49 mcg
Proprietary Blend 388 mg
hawthorn (Crategus oxyacantha) berry extract,
taurine, garlic (Allium sativum) bulb, grape seed (Vitis
vinifera) extract, grape skin (Vitis vinifera) extract,
N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine
max) isoflavones, tocotrienols
L-Arginine (as L-arginine HCl) 153 mg
L-Carnitine (as L-carnitine L-tartrate) 51 mg
Coenzyme Q10 (CoQ10)(ubiquinone 10) 25 mg
Policosanol 7 mg
Other ingredients: See label for most current information.
Contains no: sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives. This product contains natural ingredients; color variations are normal.
Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5
Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4
Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4
Types of Cholesterol
Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5
LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6
Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7
The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7
HOW IT WORKS:
HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9
Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at
The following chart summarizes the benefits of each of the ingredients in HDL Booster:
February 11, 2006 09:30 AM
Scientific References 1. Toyoda-Ono Y, Maeda M, Nakao M, Yoshimura M, Sugiura-Tomimori N, Fukami H. 2-O-(beta-D-Glucopyranosyl)Ascorbic acid, a novel Ascorbic acid analogue isolated from Lycium fruit. J Agric Food Chem. 2004 Apr 7;52(7):2092-6.
2. Breithaupt DE, Weller P, Wolters M, Hahn A. Comparison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. Br J Nutr. 2004 May;91(5):707-13.
3. Cheng CY, Chung WY, Szeto YT, Benzie IF. Fasting plasma zeaxanthin response to Fructus barbarum L. (wolfberry; Kei Tze) in a food-based human supplementation trial. Br J Nutr. 2005 Jan;93(1):123-30.
4. Wu SJ, Ng LT, Lin CC. Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos. Phytother Res. 2004 Dec;18(12):1008-12.
5. Zhao H, Alexeev A, Chang E, Greenburg G, Bojanowski K. Lycium barbarum glycoconjugates: effect on human skin and cultured dermal fibroblasts. Phytomedicine. 2005 Jan;12(1-2):131-7.
6. Gan L, Zhang SH, Liu Q, Xu HB. A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells. Eur J Pharmacol. 2003 Jun 27;471(3):217-22.
7. Gan L, Hua Zhang S, Liang Yang X, Bi Xu H. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int Immunopharmacol. 2004 Apr;4(4):563-9.
Potent Antioxidant Protection *
February 11, 2006 09:28 AM
Goji berry possesses a unique combination of flavonoids, vitamins, minerals and polysaccharides that are thought to be responsible for the antioxidant and anti-aging properties attributed to Goji. Studies have been conducted which characterize some of these antioxidant nutrients and show possible beneficial effects of the berry and its extracts on various systems and organs.
In a study published in 2004, scientists undertook an experiment to assess whether Goji berries contained compounds that would be known to exert potential beneficial effects on skin complexion and anti-aging properties. After analyzing the berry, leaf and roots of the Goji plant, they found that the Goji berry contained a unique analog of vitamin C known as 2-O-(beta-D-glucopyranosyl) Ascorbic acid. They determined that this compound was unique to the berry and not found in the other parts of the plant. Furthermore, the vitamin C compound was present in levels equivalent to those found in citrus fruits such as lemons. However, the question remained as to whether this vitamin C analog served as a precursor to vitamin C when ingested in the body. A further experiment in rats was performed to determine the intestinal absorption and tissue uptake of this vitamin C analog. The results showed that some of the compound was indeed metabolized into vitamin C in the blood, while the rest was absorbed intact. These studies suggested that the compound was easily transported from the blood into cells and tissues, where it is activated to active vitamin C. Therefore, the vitamin C from Goji berries seems to be highly absorbable and targeted for delivery to the cells that utilize it.1
Zeaxanthin is a carotenoid that is widely distributed in fruits and vegetables and, along with lutein, is present in significant amounts in the macula of the human eye. Studies suggest that the presence of zeaxanthin is highly desirable for healthy visual function. Goji berries are used in traditional Chinese herbalism to support eye health and are also known to contain a high level of zeaxanthin dipalmitate. Researchers compared the bioavailability of this naturally esterified zeaxanthin to that of an unesterified form in 12 individuals who underwent a 23-day study in which they received one form or the other, and then switched. Administration was done on day one followed by a three-week washout period. The individuals were then crossed over to get the other form on day 23 in a single administration. Analysis revealed that the esterified zeaxanthin from Goji berry caused a higher increase in plasma levels than the non-esterified form, indicating higher bioavailability.2
A second study confirmed these findings. In this study, fourteen individuals consumed 15 grams of whole Goji berries daily for 28 days. These individuals were compared to thirteen age and sex-matched controls who did not consume the berries. Fasting blood samples were taken for all individuals before and after the 28-day period. Results indicated that zeaxanthin plasma levels increased 2.5-fold in the group who consumed the berries daily, suggesting the high bioavailability of zeaxanthin from the berries.3
Goji berry was also studied on various measures of antioxidant activity. Researchers subjected three Chinese herbs, one of which was Goji berry, to various assays of reactive oxygen scavenging potential. The results indicated that all of the herbs had significant free radical scavenging properties; however, Goji berries showed the most potent scavenging effect in the assays. Goji berry was especially strong at inhibiting the formation of superoxide anion and scavenging free radicals. The researchers concluded that among these herbs, Goji could be considered the best antioxidant to promote healthy aging.4
An interesting study was performed in human skin cultures to determine the mechanism of the potentially protective effect of Goji berry extracts. Researchers found that bathing human skin cultures with an extract from Goji berry impacted the function of several enzymes that promote skin aging. This provides evidence of an anti-aging and antioxidant effect of Goji berry extract in these human skin cultures. Researchers also noted that when these skin cultures were subjected to suboptimal growth conditions (lack of adequate nutrients), supplementing the medium with this Goji berry extract allowed the skin to maintain normal metabolic functions.5 Goji berry extract contains numerous compounds that confer potent antioxidant protection to various tissues.*
January 21, 2006 01:10 PM
Omega Man is the ideal essential fatty acid and plant phytochemical formula to support optimal health, life and vitality at any age. From the athletic pursuits of your early 20’s to the health concerns of your 50’s, 60’s, and beyond, Omega Man is your answer. Let Omega Man unlock the door to a new, more vibrant, healthier you.
The Omega Man Formula
Organic Flaxseed Oil
Styrian Pumpkin Seed Oil
Plant Phytosterol Complex
Vitamin C FAQ's
December 27, 2005 05:11 PM
Vitamin C FAQ's
What is Calcium Ascorbate?
Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (Ascorbic acid). Calcium is reacted with Ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to Ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.
What does Calcium Ascorbate do?
Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.
Is this a necessary vitamin or can our bodies make enough to satisfy our needs?
Many plants and animals do not need to consume foods high in Ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into Ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of Ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.
What is the function of the Citrus Bioflavonoids?
Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.
Why are there color variations in your different Vitamin C products, and are they safe to take?
Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.
Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.
Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of Ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as Ascorbic acid.
NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.
Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Effer-C NUTRITION YOU CAN DRINK
December 27, 2005 09:49 AM
Ideal Vision from Thompson Nutritional
November 18, 2005 01:30 PM
Ideal Vision Dietary Supplement is a powerful blend of antioxidants, vitamins, minerals and herbs formulated to provide nutritive support for healthy eyesite. Recent research suggests that supplementing with antioxidants such as zinc, vitamin C, vitamin E and betaCarotene may have potential beneficial effects on eye health in certain population groups.
- 15mg Lutein
Benefits of Total Daily Formula
October 13, 2005 04:45 PM
Benefits of Total Daily Formula
All fruits and vegetables contain carotenes, the plant pigments responsible for the rich variety of colors we enjoy in the natural world. Beta carotene is the most familiar member of the carotene family. But beta carotene never exists by itself; it is always found with other carotenes in foods. We need more than just beta carotene alone. Carotenes are powerful antioxidants, which means they help reduce the body's free radical burden. Research suggests that carotenes work as a team to keep us healthy.5 Total Daily Formula provides beta carotene, alpha carotene, lutein, lycopene, zeaxanthin and cryptoxanthin from natural sources such as algal extracts, carrot oil, marigold and tomatoes (Caromix®).
Total Daily Formula uses only corn-free vitamin C (Ascorbic acid). The full daily intake of 6 tablets provides an exceptionally generous 800 mg of vitamin C.
Total Daily Formula supplies ample amounts of all essential B vitamins. Vitamin B3 is given as niacin plus an extra helping of niacinamide, the non-flush form of this important vitamin. The body uses pantothenic acid (vitamin B5) to deal with stress, so the formula provides 150 mg, which is 15 times the RDA. Vitamin B6 is another B vitamin people may run short of, so 60 mg -- 30 times the RDA -- is supplied. The formula contains 800 mcg of folic acid, the vitamin now recognized by the FDA as essential for prevention of neural tube defects in unborn babies. Folic acid also helps prevent accumulation in the body of homocysteine, a metabolite of the amino acid methionine.6 A high blood homocysteine level is now considered to be a risk factor for heart disease.7
Flavonoids, also known as "bioflavonoids." are plant pigments widely distributed throughout the plant kingdom.8 Previously known as "Vitamin P," because they help reduce capillary permeability (leakiness) flavonoids are now regarded as "semi-essential" non-vitamin nutrients that benefit health in a variety of ways.9 In addition to maintaining the structure of blood vessels, flavonoids function as versatile antioxidants. Flavonoids protect vitamin C from destruction by free-radicals, helping to preserve the body's vitamin C supply.10 Total Daily Formula provides 100 mg of pure flavonoids from 112 mg of citrus extract.
Three superior sources of Calcium
Total Daily Formula contains three of the best absorbed and most effective forms of calcium available. MCHC (microcrystalline hydroxyapatite concentrate) is a naturally-derived compound composed of calcium, plus all the minerals and organic factors in living bone tissue. MCHC has been clinically shown to benefit bone health.11 Calcium citrate malate is a very well-absorbed form of supplemental calcium shown in recent research to be helpful for postmenopausal women.12,13 Calcium glycinate is chelated with the amino acid glycine, one of the most efficient mineral carriers for effective absorption.14,15
Magnesium is essential for strong bones and healthy hearts. This versatile mineral also regulates nerve function, keeps muscles relaxed and coordinates activity of over 300 enzymes in the body.16 Total Daily Formula contains 100 percent magnesium glycinate for exceptional absorption and gentleness on the intestinal tract.17 Magnesium glycinate has been clinically tested on people with severe malabsorption with excellent results.18
Total Daily Formula provides - in addition to zinc, chromium, selenium and iodine - vanadium and molybdenum. Vanadium helps maintain normal blood sugar.19 Molybdenum works as a co-factor for enzymes that help detoxify and eliminate foreign substances from the body.20
Bioperine® for Enhanced Absorption
Bioperine® is a natural extract derived from black pepper that enhances nutrient absorption. Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine®. 21 Betaine HCL - supplies HCL (hydrochloric acid) to assist digestion. All natural tablet coating made of vegetable concentrate and beta carotene.
2. Morgan, K.J. et. al. Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition. 1985;4:195-206.
3. Lakschmanan, F.L., Rao, R.B., Kim, W.W., Kelsay, J.L. Magnesium intakes, balances and blood levels of adults consuming self-selected diets. American Journal of Clinical Nutrition 1984;40:1380-89.
4. Mertz, W. The Essential Trace Elements. Fed. Proc. 1970;29:1482.
5. Perry, G. Byers, T. Dietary carotenes, vitamin C and vitamin E as protective antioxidants in human cancers. Annu. Rev. Nutr. 1992;12:139-59.
6. Landgren, F., et. al. Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. J Int Med 1995;237:381-88.
7. Clarke, R., et. al. Hyperhomocysteinemia: an independent risk factor for vascular disease. New Eng J Med 1991;324:1149-55. 8. Havsteen, B. Flavonoids, a class of natural compounds of high pharmacological potency. Biochemical Pharmacology 32(7):1141-48.
9. Middleton, E. The flavonoids. TIPS 1984; 5:335-38.
10. Roger, C.R. The nutritional incidence of flavonoids: some physiological and metabolic considerations. Experientia 44(9):725-804.
11. Dixon, A. St. J. Non-hormonal treatment of osteoporosis. British Medical Journal 1983;286(6370):999-1000.
12. Smith, K.T. et. al. Calcium Absorption from a new calcium delivery system (CCM). Calcif Tissue Int 1987;41:351-352.
13. Dawson-Hughes, B. et. al. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. New England Journal of Medicine 1990 Sep 27;323(13):878-883.
14. Albion Research Notes Vol. 4, No. 1, ©Albion Laboratories Jan,1995.
15. Ashmead, H.D. Intestinal Absorption of Metal Ions and Chelate, Springfield: Charles C Thomas, ©1985.
16. Wester, P.O., Dyckner, T. The importance of the magnesium ion. Magnesium deficiency-symptomatology and occurrence. Acta Med Scand 1992; (Suppl) 661:3-4.
17. Albion Research Notes Vol. 3, No. 1, ©Albion Laboratories, Feb 1994.
18. Schutte, S., et. al. Bioavailability of Mg diglycinate vs MgO in patients with ileal resections. Abstract 115, AJCN 1992;56(4).
19. Cohen, N. et. al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J. Clin Invest 1995; 95:2501-09.
20. Sardesi, V.M. Molybdenum: An essential trace mineral element. Nutr Clin Pract 1993; 8:277-81.
21. Bioperine® - Nature's Bioavailability Enhancing Thermo-nutrient. Executive Summary' 1996; Sabinsa Corporation, Piscataway, N.J.
What makes Ascorbyl Palmitate so Attractive?
September 15, 2005 11:18 AM
Ascorbyl Palmitate, a fat-soluble form of vitamin c, is intended to provide nutritive support to maintain Healthy Skin and Collagen. Additionally, it helps support capillary and blood vessel integrity and provides all the Antioxidant benefits you expect from Vitamin C. The hydrophilic properties of ascorbyl palmitate also make this form unique. Unlike water-soluble forms of Vitamin C, it can cross the blood-brain barrier, the membrane located between blood and the brain that prevents certain substances from reaching brain tissue and spinal fluid.
Beauty is more than skin deep, so nourish it from the inside out with Ascorbyl Palmitate.
Ascorbyl Palmitate is a Vitamin C Ester made up of Palmitic Acid and Ascorbic Acid. Ascorbic Acid comprises approximately 42% of the total weight.
Kids will Absolutely Love DinoEFA ...
September 10, 2005 12:33 PM
Have a smart Year with Kal Dinosaurs Supplements for Kids
PYCNOGENOL AS A DIETARY SUPPLEMENT
July 13, 2005 10:01 AM
PYCNOGENOL AS A DIETARY SUPPLEMENT
While flavonoid concentrates were used in ancient times to treat a variety of human diseases, modern medicine has failed to utilize their enormous therapeutic potential. We assume RDA standards to provide us with all the vitamin C and bioflavonoids we need to be healthy. Even if these set quantities were accurate for maintaining optimal health, how many of us eat diets nutritious enough to maintain maximum health and protection? In other words, do we consume enough fruits and ve g etables to affo rd us adequate levels of vitamin C and bioflavonoids to provide the free radical protection we need?
“The USDA conducted a study in which they collected dietary information over the course of the year for four independent days. In that study 20% of the adult women had no fruit or juice for four days, and about 45% had no citrus fruit or citrus fruit juice in four days.”6
MALNUTRITION IN THE MIDST OF PLENTY?
Only 9% of our population gets and eats enough fruits and vegetables on a consistent basis. Unquestionably, most of us are not getting enough vitamin C and flavonoid compounds from our diets.
In addition, it’s important to remember that modern farming techniques, pre m a t u re harve sting of fruits and vegetables, indefinite cold storage, freezing, canning and cooking may denature food of its vitamin C and bioflavonoid content. Because we know that diseases are often nothing more than nutritional deficiencies, we must make adequate supplementation a priority if we want to enhance our longevity.
As mentioned earlier, biofl avonoids must combine with vitamin C (Ascorbic acid) in order to be effective. Mother nature was well aware of this synergistic relationship, as most plant biof l avonoids accomp a ny vitamin C compounds. In addition, the best, most bio-active and bioavailable flavonols must be chosen for their antioxidant properties. An overwhelming consensus exists that Pycnogenol may be the ideal choice.
New* Improved formula - Cholest-Response Lower Cholesterol
July 08, 2005 09:27 AM
New & Improved Formula!
4 tablets contain:
Suggested Use: Take 4 tablets each night or as recommended by your health care professional.
We offer Source Naturals at 46% OFF Man. Suggested Retail
NEW PRODUCT ANNOUNCEMENT
July 05, 2005 06:29 PM
The Most Comprehensive Antioxidant Formula Available!
Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
gamma-Vitamin E Complex 500 mg
Quercetin 100 mg
Kal - Vanadyl Complex now with Cinnamon Bark for Blood sugar
July 01, 2005 03:07 PM
Cinnamon May Help Lower Blood Sugar!
Kal Vanadyl Complex
Vanadyl Complex - Dietary supplement contains Cinnamon Plus a variety of natural ingredients intended to provide nutritive support for normal, healthy blood glucose, and glycogen synthesis. The formula Contains:
100mg Vitamins C (as Ascorbic Acid) - a water soluble nutrient that may help support carbohydrate metabolism and healthy blood glucose levels.
50 mcg Chromium (as Chromium Picolinate) - an essential micromineral that may also help provide nutritive support for healthy carbohydrate metabolism.
10mg Vanadyl Sulfate - the salt of the mineral vanadium that may support glucose oxidation and glycogen synthesis.
June 25, 2005 08:13 PM
1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and Ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.
SUMMARY AND CONCLUSIONS
June 25, 2005 08:10 PM
SUMMARY AND CONCLUSIONS
1 . Chit osan Provides a Realist ic Approach t o Fat and Fiber Int ake.
Low-fat, high-fiber advocates have recommended a diet that is calorically fueled between 10 and 20 percent fat and includes 35 to 45 grams of fiber. Unfortunately, most of us, no matter how good our intentions are, will not be able to sustain this type of diet. Therefore, if we are going to face facts, a diet that reduces fat to 20-30 percent of the total caloric value and increases fiber to 20-30 grams/day is much more realistic and will help significantly in controlling weight, avoiding artery disease and promoting good colon health. Taking Chitosan prior to eating a meal can make dietary fat goals much more attainable while promoting a number of desirable health benefits. Because obesity ranks among the top ten diseases (which, by the way, are almost all related to obesity), the availability of a safe, health-promoting fat binder is desirable.
Weight control needs to be realistic and effective. Workable weight loss programs are few and far between and usually involve a life style that many of us can never incorporate. While Chitosan is not a panacea for maintaining our youthful figures, it could be a very powerful dietary complement, facilitating what might otherwise be unattainable. Lowering the amount of dietary fats we eat, exercising more, and making sure we get enough fiber seems to be the winning combination for health and longevity. Chitosan is a valuable tool to use in attaining optimal nutrition and robust health.
2 . Chitosan Is an Effective Fat Binder.
While all the previously mentioned properties of Chitosan are notable, its extraordinary ability to bind fats promises to be its most valuable asset. To reiterate, getting rid of fat after it has been stored as adipose tissue is much more difficult than neutralizing its effects before it enters the blood stream. Chitosan accomplishes this formidable task by converting fat into a form that the body does not absorb and subsequently expels.
Any of us who occasionally eat southern fried chicken, a Big Mac, or a slice of cheesecake every once in a while can profoundly benefit from the fat binding action of Chitosan. As a fat binder, Chitosan can significantly reduce the amount of fat that enters our blood stream. Consider the possibilities. The foods mentioned above are full of excess fat grams. If you take four capsules (1 gram) of Chitosan with Ascorbic acid, which is generally recommended, the fat content of that food is dramatically lowered.
Remember the discussion on how the liver has to deal with excess fat?
Chitosan decreases the liver’s work load which lightens the stress put on other body organs by the presence of excess fat. In other words, Chitosan eases the metabolic processes that kick in after we eat excess fat. As far as our metabolic processes know, those fat grams may as well never have existed. 4 . Why Chit osan Is Called t he Fiber of t he Fut ure. After years of fiber “hyping” most of us are well aware of the profound benefits that fiber has for human health and longevity. Fiber is considered a dieter’s best friend. It has also been linked to slower rises in blood glucose which also profoundly affects how we store excess calories and when we feel hungry. Most fibers are hydrophilic which means they repel fat and attract water. Psyllium, for example, is used for its bulk forming action. This type of fiber absorbs water and is easily passed through the intestine, helping to maintain a normal bowel function.
Chitosan is different. While it possesses many of the same benefits as plant fibers like psyllium, Chitosan is “lipophilic” meaning that it “loves fat” It is a positively charged fiber that binds to negatively charged fatty acids. A fiber that attracts fat is unique to say the least.
June 25, 2005 08:04 PM
Chitosan is not only very useful, it is also very safe. Chitosan has been used extensively in nummerous industrial, health, and food applications.66,71 Nevertheless, all substances when taken improperly or in gross excess can be detremental to our well-being. For example, water is normally safe when swallowed. On the other hand, breathing large amounts of water can be deadly. Similarly breathing air is relatively safe whereas intraveneous injections of air are usually fatal. To determine the relative safety of various foods, scientists run experiments to determine the food’s toxic level or LD50. Chitosan has been found to have an LD50 of over 16 grams/day/kg body weight in mice.122 Chitosan is a fiber which expands to form a gel in the acidic environment of the stomach. The problems encountered with extremely high doses of chitosan were caused by gastric dehydration and impaction due to the expansion of the fiber.123 To put these data in context, the authors compared Chitosan to common sugars stating “[I]t appears that chitosan is less toxic than these substances.”122 Mice are not men. For safety purposes data gathered in mice is divided by 12 to get the human equivalent.124 The relative LD50 in humans then would be 1.33 grams/day/kg. Given that an average person weighs 150 pounds or 70 kg, this means that the toxic amount for a person would be greater than 90 grams per day. Conservatively, one could feel very confident below the 10% level, or 9 grams per day. Clinical studies have used amounts in the 3-6 grams per day range with no adverse effects. As with any fiber, a person is well advised to drink plenty of water. Changing our diets affects our colon function. Constipation or diarrehea may occur in some persons depending on their individ-ual constitutions and on how well the Chitosan supplement was originally formulated. Even though Chitosan is not digestible by our enzymes, it can and is degraded by soil and water microorganisms. This makes Chitosan environmentally friendly. This was recently acknowledged by the US Environmental Protection Agency when it exempted Chitosan from tolerance level testing.68 Any breakdown of chitosan by our colon microflora would release D-glucoseamine which is itself a wonderfully beneficial nutrient for osteoarthritis sufferers.125 Because Chitosan can bind lipids and certain minerals, it is best to take essential fatty acid supplements, fat soluble vitamins and mineral supplements separate from Chitosan. Taking Chitosan with D- or L-Ascorbic acid helps increase the amount of fat bound and decrease the loss of minerals. 77,126
MECHANISMS OF CHITOSAN FAT- BINDING
June 25, 2005 08:02 PM
MECHANISMS OF CHITOSAN FAT- BINDING
The exact way(s) that Chitosan prevents fat absorbtion is not fully understood but a number of experimental observations support two basic mechanisms. The first mechanism involves the attraction of opposite charges which can be compared to the attraction of opposite magnetic poles. The second entrapment mechanism can be compared to the effect of a net. In the first mechanism the positive charges on chitosan attract the negatively charged fatty acids and bile acids binding them to the indigestible chitosan fiber. This mechanism can explain why chitosan reduces LDL cholesterol levels.
Our bodies make bile acids in the liver using the cholesterol from LDL. When chitosan binds bile acids it increases the rate of LDL loss thus improving the LDL to HDL ratio. If enough bile acids are bound, the fats are not solublized, which prevents their digestion and absorption. The second mechanism (figure 2) describes a netting effect of chitosan fiber.
In this model the Chitosan wraps around fat droplets and prevents their being attacked and digested by lipid enzymes. Fats unprotected by Chitosan are digested and absorbed. The “netting” mechanism has been seen to operate in vivo. 108
Substances that Enhance the Action of Chitosan
Fibers can be likened to a tangled-up chain. Fibers must “unravel” in order for them to be of maximum benefit to us. “Unraveling” is especially critical for chitosan because each link has a hook on which to attach lipids. Chitosan can absorb an average of 4 to 5 times its weight in lipids. Reports of numbers above and below this range have also been reported and may well reflect the rate or extent of unraveling that had taken place. Fiber formulations can be prepared that unravel rapidly and swell quickly. These highly effective formulations are called superabsorbants. When certain substances are added to chitosan, its remarkable fat-binding ability can be significantly enhanced.
D-Ascorbic acid (erythorbic acid) and L-Ascorbic acid are C-vitamins which enhance chitosan’s ability to bind lipids. Combining chitosan with Ascorbic acid results in even less fat absorption and greater fecal fat losses.77,108 In one study the addition of Ascorbic acid to a chitosan enriched diet increased fecal fat losses by 87 percent and decreased fat absorption by over 50 percent.77
Cholesterol oxides cause lesions in artery walls which predispose blood vessels to collect plaque. These dietary cholesterol oxides profoundly influence the initiation of heart disease.Free radicals can also contribute to the formation of cholesterol oxides which are even more likely to damage the heart. Cholesterol oxides have been found in deep-fried foods, powdered eggs, processed meats and in human blood itself. Consequently, taking antioxidants like Ascorbic acid is vital to protect against the cellular damage this type of free radical causes.112
In feeding experiments with animals, adding citric acid to a chitosan enriched diet resulted in a decreased feed consumption.77 The most likely explanation for this effect is that the citric acid may be enhancing the swelling action of chitosan leading to a sense of fullness, producing satiety and appetite suppression.
Indoles are remarkable phytochemicals which have the ability to selectively activate certain Mixed Function Oxidases (MFOs).113 These MFO’s help balance estrogen metabolism and prepare dietary toxins for elimination before they are absorbed. The presence of fiber in the intestines provides a bulk agent to carry the metabolized toxins out of the body. Chelat ed Minerals The very best approach to weight loss is to nutritionally augment food choices with nutrient supplementation. Certain biochemical compounds are essential to promoting vigor during the process of thermogenesis. Chelated minerals act to bolster, support and protect the organ systems of the body.114,115
For example, when fat is burned, heat and energy are released. If a lack of certain minerals exists, energy levels will drop. Minerals help to transport needed nutrients to depleted areas of the body, thereby stemming off the fatigue we so often experience after eating a fatty meal. Even more importantly, free radicals are released whenever fat is consumed and burned and the presence of chelated minerals helps to expedite the removal of these metabolites and facilitate the availability of fuel for energy.
Essential Fatty Acids
Prostaglandins control and balance many body functions. The dietary building blocks for making prostaglandins are the essential fatty acids (EFAs). The role of prostaglandins in weight loss has been extensively discussed in a recent review.116 EFAs exert profound lipid-lowering effects.They reduce the synthesis of triglycerides and very low density lipoproteins (bad cholesterol) in the liver. EFA supplementation coupled with a low-cholesterol, low-saturated fat in diet produces a complementary effect in lowering serum lipid levels.117 Garcinia Cambogia ( Hydroxy Cit ric Acid) Garcinia Cambogia contains hydroxycitric acid (HCA). This form of citric acid inhibits the liver’s ability to make fats out of carbohydrates.118
Carbohydrates are converted to glycogen stores, not fat stores, giving the body a better energy reserve and an increase in stamina.119 Ephedra And Thermogenisis Thermogenesis means “creating heat.” This is one of the ways our bodies have of burning off excess calories and maintaining a constant weight.120 This is an area of weight management research that is being intensely studied. When we repeatedly yo-yo diet or abuse ourselves by eating too much, our thermogenic ability may be reduced. Numerous animal and human studies have confirmed the benefits of ephedra and methylxanthines in inducing weight loss and restoring thermogenic responsiveness.43,44,121
CHITOSAN: The Fiber that Binds Fat
June 25, 2005 07:55 PM
Chitosan is a natural product that inhibits fat absorption. It has the potential to revolutionize the process of losing weight and by so doing, reduce the incidence of some of the most devastating Western diseases we face today. Chitosan is indigestable and non-absorbable. Fats bound to chitosan become nonabsorbable thereby negating their caloric value. Chitosan-bound fat leaves the intestinal tract having never entered the bloodstream. Chitosan is remarkable in that it has the abilty to absorb an average of 4 to 5 times its weight in fat.60
The same features that allow chitosan to bind fats endow it with many other valuable properties that work to promote health and prevent disease. Chitosan is a remarkable substance whose time has come.
Chitin, the precursor to Chitosan, was first discovered in mushrooms by the French professor Henri Braconnot in 1811.61 In the 1820’s chitin was also isolated from insects.62 Chitin is an extremely long chain of N-acetyl-D-glucoseamine
glucoseamine units. Chitin is the most abundant natural fiber next to cellulose and is similar to cellulose in many respects. The most abundant source of chitin is in the shells of shellfish such as crab and shrimp. The worldwide shellfish harvest is estimated to be able to supply 50,000 tons of chitin annually.63 The harvest in the United States alone could produce over 15,000 tons of chitin each year.64
Chitin has a wide range of uses but that is the subject of another book. Chitosan was discovered in 1859 by Professor C. Rouget.65 It is made by cooking chitin in alkali, much like the process for making natural soaps. After it
is cooked the links of the chitosan chain are made up of glucosamine units. Each glucosamine unit contains a free amino group. These groups can take on a positive charge which gives chitosan its amazing properties. The stucture of chitosan is represented schematically in Figure 2. Research on the uses of chitin and Chitosan flourished in the 1930s and early 1940s but the rise of synthetic fibers, like the rise of synthetic medicines, overshadowed the interest in natural products. Interest in natural products, including chitin and chitosan, gained a resurgence in the 1970s and has continued to expand ever since. Uses of Chit osan Some of Chitosan's major uses—both Industrial and Health and Nutritional—are listed in Tables 5 and 6.
Chitosan has been used for about three decades in water purification processes. 67 When chitosan is spread over oil spills it holds the oil mass together making it easier to clean up the spill. Water purification plants throughout the world use chitosan to remove oils, grease, heavy metals, and fine particulate matter that cause turbidity in waste water streams.
Fat Binding/ Weight Loss
Like some plant fibers, chitosan is not digestible; therefore it has no caloric value. No matter how much chitosan you ingest, its calorie count remains at
fibers, chitosan’s unique properties give it the ability to significantly bind fat, acting like a “fat sponge” in the digestive tract. Table 7 shows a comparison of chitosan and other natural fibers and their ability to inhibit fat absorption. Under optimal conditions, Chitosan can bind an average of 4 to 5 times its weight with all the lipid aggregates tested.60 (NOTE: This assessment was made without the addition of Ascorbic acid which potentiates this action even further.77 Studies in Helsinki have shown that individuals taking chitosan lost an average of 8 percent of their body weight in a 4-week period.76 Chitosan has increased oil-holding capacity over other fibers.108 Among the abundant natural fibers, chitosan is unique. This uniqueness is a result of chitosan’s amino groups which make it an acid absorbing (basic) fiber. Most natural fibers are neutral or acidic. Table 7 summarizes the in vivo effects in animals of various fibers on fecal lipid excretion. As can be seen from the results listed, ingestion of chitosan resulted in 5-10 times more fat excretion than any other fiber tested. D-Glucosamine, the building block of chitosan, is not able to increase fecal fat excretion. This is due to the fact that glucosamine is about 97 percent absorbed while chitosan is nonabsorbable. Fats bound to glucosamine would likely be readily absorbed along with the glucosamine. Chitosan, on the other hand, is not absorbed and therefore fats bound to chitosan can not be absorbed.
Chitosan has the very unique ability to lower LDL cholesterol (the bad kind) while boosting HDL cholesterol (the good kind).78 Laboratory tests performed on rats showed that “chitosan depresses serum and liver cholesterol levels in cholesterol- fed rats without affecting performance, organ weight or the nature of the feces.”79 Japanese researchers have concluded that Chitosan “appears to be an effective hypocholesterolemic agent.”80 In other words, it can effectively lower blood serum cholesterol levels with no apparent side effects. A study reported in the American Journal of Clinical Nutrition found that Chitosan is as effective in mammals as cholestryramine (a cholesterol lowering drug) in controlling blood serum cholesterol without the deleterious side effects typical of cholestryramine. 81 Chitosan decreased blood cholesterol levels by 66.2 percent.82 It effectively lowered cholesterol absorption more than guar gum or cellulose.83 Laboratory test results indicated that a 7.5% chitosan formula maintained adequate cholesterol levels in rats, despite a dramatic increase in the intake of cholesterol. 84
June 25, 2005 07:29 PM
Stated simply, Chitosan is an extraordinary fat binder. Chemically speaking, Chitosan is an amino polysaccharide that has the ability to “bind” lipids in the stomach before they are absorbed through the digestive system into the bloodstream. The presence of fats in the blood can raise cholesterol levels, contribute to cardiovascular disease and cancer, and most importantly, promote obesity. Not only does chitosan attract and inhibit fats, it offers an array of other desirable physiological benefits that can foster optimal health and longevity. In an era where everyone is interested in decreasing their fat intake, Chitosan can act as a remarkable supplement. When taken prior to eating or during a meal, it can significantly reduce the body’s absorption of dietary fats. Of equal significance is the fact that when Chitosan is combined with other compounds such as citric acid, Ascorbic acid and phytochemicals called indoles, its action is enhanced, making it far more valuable as both a fat binder and dietary health aid. Fat is responsible for more of our health “ills” than any other single substance. Chitosan provides a simple and safe complement to smart eating and exercise to control lipid levels.
June 25, 2005 07:28 PM
The lifestyles of western cultures have been determined to be major contributing factors in diseases such as heart disease, diabetes and cancer. The most commonly cited factors are inadequate fiber intake, excessive consumption of fats, and a lack of exercise. Educational efforts have resulted in an increase in involvement in various exercise regimines. The consumption of fats, however, continues to increase in spite of the dire warnings that have been publicized. A reduction of fat intake, from an average of 40 percent of the diet to less than 25 percent could have dramatic effects on the health and well-being of the population as a whole. Intake of fiberous foods reduces fat consumption generally through the bulking action of the fibers which leads to a feelings of fullness. Some fibers have an ability to entrap fats in their gelatinous matrix and prevent their absorption. The most effective fiber for preventing fat absorption is chitosan. Chitosan’s fat entrapment properties can be enhanced by combination with Ascorbic acid and other dietary ingredients. Fat entrapment by chitosan has been shown in animals and can be readily demonstrated. The use of chitosan in nummerous environmental, agricultual, biomedical, and health-related areas is well documented. Chitosan has been found to be safe for oral consumption.
GARLIC (allium sativum)
June 25, 2005 09:54 AM
GARLIC (allium sativum)
Common Names: Stinking Rose, Poor Man’s Treacle
Plant Parts: bulb
Active Compounds: Garlic contains more than 200 chemical compounds.
Some of its more important ones include: volatile oil with sulphur-containing compounds: (allicin, alliin, and ajoene), and enzymes: (allinase, peroxidase and myrosinase). Allicin is what gives garlic its antibiotic properties and is responsible for its strong odor. Ajoene contributes to the anticoagulant action of garlic. Garlic also contains citral, geraniol, linalool, Aphellandrene and B phellandrene. The allyl contained in garlic is also found in several members of the onion family and is considered a very valuable therapeutic compound.
Pharmacology: The allicins contained in garlic have a fibrinolytic activity which reduces platelet aggregation by inhibiting prostaglandin E2. Allivium sativum has also exerted some effect on glucose tolerance for both hypo-and hyperglycemia by reducing insulin require-ments to control blood sugar. The compounds contained in garlic have also demonstrated their ability to lower total serum cholesterol and triglyceride levels while elevating HDL levels. LDL synthesis is suppressed by garlic. Garlic allicins have also acted as a larvacide and bacteriostat, active against gram-positive or gram-negative microorganisms. In addition, the compounds can destroy certain fungi such as Candida albicans. Several other microbes are effected by garlic, including some viruses. Most researchers agree that the sulfur containing compounds of garlic, especially allicin, alliin, cy-croalliin, and dialllyldisulphide are the most biochemically active. In addition, certain unidentified substances of garlic will probably emerge as other therapeutic agents.
(Note: Before a bulb of garlic is crushed or chopped, it contains relatively few medically active compounds. Once it is cut, however, chemical reactions take place which create dozens of new compounds.)
Vitamin and Mineral Content: B-vitamins especially B-1, vitamin C, vitamin A, flavonoids, Ascorbic acid, phosphorous, potassium, sulphur, selenium, calcium, magnesium, germanium, sodium, iron, manganese and trace iodine. Seventeen amino acids are found in garlic, including eight essential ones.
Character: antibiotic, antihistamine, anticoagulant, expectorant, antibacterial, antiparasitic, alterative, diaphoretic, diuretic , expectorant, stimulant, antispasmodic, promotes sweating, lowers blood sugar and blood cholesterol levels, lowers blood pressure Body Systems Targeted: respiratory, cardiovascular, digestive, and nervous systems
RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available
June 24, 2005 05:34 PM
The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.
Bio-Aligned Antioxidant Support
RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.
Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.
Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.
Nourishing the Brain
Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.
Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.
The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and Ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.
Skin & Connective Tissue
Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.
Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.
Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.
DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.
Living Longer, Living Better Strategies for Wellness
Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.
Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.
Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf
Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein
Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts
Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric
Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE
Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc
Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf
June 23, 2005 11:50 AM
CLINICAL APPLICATIONS OF CAPSICUM
June 23, 2005 11:20 AM
CLINICAL APPLICATIONS OF CAPSICUM
Capsicum is a remarkable whole body stimulant that can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain and fight off infection. One very authoritative work on African plants suggests that Capsicum’s “regular ingestion is highly beneficial in hemorrhoids, varicose veins, anorexia, liver congestion and vascular conditions . . .the indigenous inhabitants of Africa and of the Antilles are remarkably free form all of these conditions as they use Capsicum fruit in their diet.”10 Most of the therapeutic actions of Capsicum are attributed to the alkaloid or glucoside content of the herb.11 The latest scientific studies conducted with Capsicum will be discussed in subsequent sections.
Because Capsicum boosts peripheral circulation and stimulates organ secretion, it expedites the therapeutic delivery and action of other herbs. In other words, the medicinal benefits of these herbs reach infected or inflamed tissue more rapidly due to enhanced blood flow.12 Consider the following statement: “Cayenne will insure the rapid and even distribution of the active principles of the rest of the herbs to critical function - al centers of the body, including those involved in cellular respiration, metabolism, data transmission, and neural-hormonal activation. Cayenne is included in several other blends for this reason. In extremely small quantities it can dramatically increase the efficiency of most other herbs.”13 Many health practitioners believe that the key to healing is CAPSICUM stimulation. Capsicum stimulates eve rything from blood flow to peristaltic action in the stomach, to intestinal transit time. The re m a rkable ability of Capsicum to stimulate organ secretion and even heart action makes it one of the strongest natural stimulants known. Se veral different kinds of herbal blends targeting various body systems will utilize Capsicum to boost the formula’s efficacy.
Capsicum is said to be unequaled for its ability to boost circulation and increase heart action. Interestingly, cultures who consume significant amounts of cayenne pepper in their diet have much lower rates of cardiovascular disease.14 Capsicum exerts a variety of desirable actions on the entire card i ovascular system. It has the extraordinary ability to enhance cardiovascular performance while actually lowering blood pressure.15 A quote taken from a card i ovascular publication re a d s , “Capsaicin has also been shown to prolong cardiac action potential in atrial muscle . . .”16 Michael T. Murray, N.D., has stated, “ Cayenne pepper [Capsicum] should be recommended as a food for its beneficial antioxidant and cardiovascular effects.”17 Herbalists have considered Capsicum as a superior “f o o d” for the heart. In fact, in cases where a heart attack is suspected administering capsicum in hot water has been thought to help lessen the severity of the attack. Capsicum can also be placed on or under the tongue in emergencies involving heart attack, stroke or hemorrhaging. 18 Note: Using Capsicum for any heart-related problem, especially a suspected heart attack should never take the place of medical attention or a physician’s care.
CAPSICUM Blood Cholesterol Reducer
Various studies have conclusively demonstrated that Capsicum reduces the risk of developing atherosclerosis (hardening of the a rteries) by reducing blood cholesterol and triglyceride levels .19 Additional clinical studies conducted in India found that when cayenne was ingested along with dietary cholesterol, the typical rise in liver and blood serum cholesterol levels was significantly inhibited. In addition, bile acids and free cholesterol were subsequently eliminated from the body through the stool.20 Interestingly, these tests revealed that using Capsicum was actually more effective in reducing cholesterol that capsaicin alone.2 1 Daniel Mowrey, Ph.D., emphatically points out that this is just one of many examples of the superiority of whole botanicals as opposed to their isolated components.22 Note: Using Capsicum in combination with Hawthorn is a particularly good cardiovascular tonic.
Blood Pressure Equalizer
While an added bonus of Capsicum’s capability to lower blood serum cholesterol is a decrease in blood pressure, additional evidence strongly suggests that the herb initiates other mechanisms that fight hypertension .23 “Cayenne, according to another study, also reduces the blood pressure in an even more direct manner: a number of years ago, a team of researchers discove red that capsaicin acts in a reflexive manner to reduce systemic blood pressure, a kind of coronary chemoreflex.”24 Adding Garlic to Capsicum creates an even better therapeutic blend for treating hypertension.
Blood Detoxification CAPSICUM
“Cayenne is a kind of catalyst in the blood purification process . . . it acts as a diaphoretic, stimulating the excretion of wastes in the swe a t . ”25 Because Capsicum stimulates organ secretion and boosts peripheral blood flow, it would only stand to reason that it would also facilitate the faster removal of toxins from the bloodstream and lymphatic system. You may have already noticed that Capsicum is frequently added to blood-purifying herbal combinations. Circulatory Booster Researchers have found that the simulating action of Capsicum on surface capillaries can help to pre vent cold hands and feet.2 6 For this reason, it may be helpful for Reynaud’s Syndrome. Old remedies using Capsicum have even recommended placing it in socks to warm the feet and to help prevent frostbite. An old folk cure for a chilled body was a steaming hot cup of Capsicum tea. Free Radical Scavenger The rich flavonoid content of Capsicum gives it significant antioxidant capabilities. A recent study conducted in 1995 showed that Capsicum has a higher Ascorbic acid content than chiles from the jalapeno or serrano varieties .27 Vitamin C and bioflavonoids can scavenge for dangerous free radicals which cause tissue damage and can predispose organs to degenerative diseases. Free radicals are found everywhere and are created as by-products of metabolic p rocesses including the act of breathing itself. Pollutants can expose the body to free radicals. An interesting study done in Mexico City and published in 1993 found that Capsicum extract was able to modulate the mutagenic activity of urban air samples.28 In other words, these potentially dangerous nitro - a romatic compounds found in polluted air were kept from mutating by red chile extract.29 Chemical breakdowns of Capsicum have also found that CAPSICUM the pepper is high in Provitamin A, which significantly contributes to its healing ability and immune fortification.30 Anti-Carcinogenic Compound Anti-cancer research recently tested Capsicum on laboratory rats and found that it does indeed demonstrate anti-cancer properties by inhibiting certain enzymes which can initiate the mutation of cells.31 What this implies is that taking Capsicum can afford the body some protection against the cellular mutation which occurs in malignant growths. Capsicum actually inhibited the formation of dangerous metabolites under laboratory conditions where they should have normally been activa t e d .3 2 This study implies that Capsicum may have many more sophisticated bio-chemical actions than previously thought.
An Impressive Pain Killer
Capsaicin has recently emerged as a remarkably effective pain reliever and has become the subject of recent clinical research . Applying capsaicin in cream or ointment form to painful joints, scar tissue or other painful conditions involving peripheral nerves confuses pain transmitters. In other worlds, capsaicin temporarily disrupts sensory nerve cell biochemistry there by impeding the relay of pain sensations from the skin surface. It does this by inhibiting a neurotransmitter called substance P. This specific compound is thought to be the main mediator of pain impulses from peripheral nerve endings.33 Substance P has also demonstrated its ability to inhibit inflammatory pain generated in arthritic joints in much the same way.34 Today, several over-the-counter topical preparations utilize capsaicin for the pain of arthritic joints. The ability of Capsicum to control severe and unresponsive pain is significant, to say the least. Modern clinical utilization of topical capsaicin may offer signifi-cant relief for a number of painful conditions including: diabetic neuropathy, cluster headaches, post-amputation pain, post-mastectomy pain, shingles and painful scar tissue.35
In the early spring of 1996, prime time national news show s reported that scientists had found that individuals who had suffered from chronic pain in post-surgical scars (heart bypass, arterial grafts, etc.) were successfully treated with topical preparations containing capsaicin. While this may have been news to many of us, clinical studies had been already published for several years that capsaicin held profound value for various kinds of pain which did not respond to established medical treatments. Typically surgical scars and regions around them can produce persistent pain or can be very sensitive to the touch even when completely healed. This type of pain phenomenon seems to respond well to capsaicin ointments and creams.
When capsaicin preparations were applied following mastectomy or breast reconstruction, pain was significantly relieved. Se veral double blind studies found that using capsaicin creams four times daily for 4 to 6 weeks resulted in much less frequent occurrence of sharp, jabbing pain.3 6 All thirteen patients studied had a 50 percent or greater improve m e n t .3 7 Various unpleasant sensations other than pain also improved with topical applications of capsaicin creams.38
MOUTH SORES FROM RADIATION OR CHEMOTHERAPY
A fascinating study conducted at the Yale Pain Management Center discove red that capsaicin could ve ry significantly lessen pain caused by mouth sores which frequently develop after chemotherapy or radiation.39 Apparently delivering the capsaicin in the form of soft candy (taffy) enabled the substance to be retained in the mouth long enough to desensitize the nerve endings causing the pain. Each one of the eleven case studies re p o rted that their pain had decreased and in two patients, it stopped entirely.40
Diabetic neuropathy is a painful nerve condition which can develop in cases of prolonged diabetes. Several double-blind studies have supported the considerable value of capsaicin creams for relieving the pain associated with this disorder.41 The results of a controlled study using Capsicum for seve re cases of diabetic neuropathy which did not respond to conventional therapy were published in 1992. A cream containing Capsicum was applied to painful areas four time a day and pain was carefully e valuated for 8 weeks at two-week intervals. The results we re impressive, to say the least. In the 22 patients who used the Capsicum the following results we re re c o rded: “Capsaicin tre a tment was more beneficial than vehicle treatment in the overall clinical improvement of pain status, as measured by physician’s global evaluation and by a categorical pain severity scale . . . In a follow-up study, approximately 50 percent of the subjects reported improved pain control or were cured . . .”42 No t e : While there was a burning sensation when the Capsicum c ream was first applied, some subjects found that its magnitude and duration lessened with continued application.43
The FDA has approved capsaicin-based ointments for the treatment of pain that results from diseases like shingles. Again, numerous studies have documented the value of capsaicin for decreasing the miserable nerve-related pain associated with shingles. The general consensus derived from these tests were that approximately 50 p e rcent of people suffering from shingles responded well to capsaicin creams, some even after 10 to 12 months.44
Note: If blisters accompany a shingles outbreak, it is better to wait until they have healed before using any capsaicin-based ointments or creams.
RELIEF FOR BURNING FEET
Frequently an uncomfortable “burning” sensation in the feet will occur in many people, particularly in diabetics. As ironic as it may seem, using capsaicin creams may actually alleviate this burning. “In various studies, diabetics who treated their burning feet with capsaicin got greater improvement and we re able to walk more easily than those not using the cream.”45 In addition, using topical applications of capsaicin as opposed to strong, oral drugs is much more preferable.
Clinical tests have confirmed that topical capsaicin ointments substantially alleviate the miserable pain that characterizes osteoand rheumatoid arthritis.46 These studies revealed that using 0.075 capsaicin cream reduced tenderness and pain.47 Dr. Michael T. Murray writes: “ . . . seventy patients with osteoarthritis and thirty - one with rheumatoid arthritis received capsaicin or placebo for 4 weeks. The patients were instructed to apply 0.025 percent capsaicin cream or its placebo to painful knees four times daily. Significantly more relief of pain was reported by the capsaicin-treated patients than by the placebo patients throughout the study . . .”48 Anyone suffering from osteo or rheumatoid arthritis should evaluate the effectiveness of capsaicin ointments for joint pain. Ester Lipstein-Kresch, M.D., has studied the effectiveness of capsaicin creams for arthritis and has stated: “You need to apply it three or four times a day on the affected area for at least two weeks before you’ll see any improvement. An initial burning sensation at the site is not unusual for the first few days, but this goes away with continued application.”49 Note: Capsaicin is also useful for tennis elbow due to its ability to block the transmission of pain.
MIGRAINE HEADACHES (CLUSTER TYPE)
Topical applications of capsaicin ointments intranasally may also help to relieve the pain of a specific kind of migraine headache called cluster headaches. Cluster headaches are characterized by s e ve re pain which typically radiates around one eye. The term “cluster” refers to the fact that these headaches tend to occur in clusters of one to three per day and can recur at intervals. Headache pain and severity we re reducing in groups using intranasal capsaicin.5 0 This type of capsaicin treatment should be done under a physician’s care. There is some speculation that capsaicin may be more effective in pre venting migraines before they develop into a full blown attack.51
June 23, 2005 10:49 AM
How many of us give the red hot chile pepper the respect it d e s e rves? Mo re often than not, most of us re g a rd red pepper or Capsicum as nothing more than the spice added to give Cajun and Mexican cuisine its piquant kick. Technically speaking, caye n n e pepper is the strongest red pepper variety of the Capsicum family, with paprika being the mildest.
Throughout this discussion, the terms capsicum and cayenne pepper will be used interchangeably. For our purposes, it’s important to know that herbalists have designated both of these terms for the same botanical agent. Health practitioners have known for centuries that Capsicum is much more than a culinary spice. Because they considered it a “ h o t” plant, Chinese physicians utilized it for physiologic conditions that needed stimulation. Capsicum or Cayenne Pepper is one of the few herbs that can be measured by its BTU or thermal units. In other words, it is a hot and stimulating pepper plant that can generate heat.
Recently, new and very valuable medicinal uses for Capsicum h a ve emerged through scientific inquiry. The red chile pepper is experiencing a rediscovery among health care practitioners, who have only just begun to uncover its marvelous therapeutic actions. It has been referred to as the purest and most effective natural stimulating botanical in the herbal medicine chest. The most recent clinical findings re g a rding Capsicum will be explored in our discussion with special emphasis on Capsicum’s ability to heal ulcers, protect stomach mucosa and alleviate peripheral pain. Unquestionably, Capsicum exe rts potent physiological and pharmacological effects without the side-effects commonly associated with powerful medicinal drugs. Ironically, in the past, Capsicum’s classification as a hot and spicy substance has done it a disservice. Because Capsicum is fiery and pungent, it is frequently regarded as dangerous and unpalatable. To the contrary, if it is used properly, Capsicum can be perfectly safe and impressively effective against a wide variety of physical disorders ranging from indigestion to ulcers to migraines. It s ability to lower blood cholesterol, boost circulation and even step up metabolism are worth serious consideration. In addition, its value for mental afflictions like depression must also be assessed. In a time when the notion of treating disease after the fact is more the rule than the exception, Capsicum offers protection from infectious invaders by boosting the effectiveness of the immune system. Today, amidst the over prescription of antibiotic drugs, Capsicum emerges as a potent immune fortifier, antioxidant and infection fighter.
A powerful compound called capsaicin is what gives Capsicum its bite and is also responsible for most of its beneficial effects on human physiology.1 The hotter the pepper, the higher its content of capsaicin.2 The re m a rkable pro p e rties of capsaicin will be discussed and documented clinical evidence supporting the use of capsaicin will be delineated. It is important to realize in evaluating this herb that while it can be used alone, Capsicum is frequently added to herbal combinations to potentiate their overall action. This fact alone attests to the powerful but safe stimulant action of Capsicum. Stimulation is thought to be one of the keys to swift and complete healing. Capsicum is ascending in prestige and is regarded as a modernday botanical which is accruing new and impressive credentials. The fruit of this particular pepper plant is a valuable herbal treasure. It is vital to our health that we inform ourselves about its many medicinal uses.
CAPSICUM (CAPSICUM ANNUUM)
Common Names: Cayenne Pepper, Red Pepper, African Bird Pepper, Bird Pepper, Spanish Pepper, American Red Pepper Plant Parts: Fruit Active Compounds: alkaloids (capsaicin), fatty acids, flavonoids, volatile oil, carotene pigment Nutritional Components: Capsicum is rich in Vitamin C (Ascorbic acid) and Zinc, two nutrients which are vital for a strong and healthy immune system. It is also high in vitamins, A, C, rutin (a bioflavonoid), beta carotene, iron, calcium and potassium. Capsicum also contains magnesium, phosphorus, sulphur, B-complex vitamins, sodium and selenium. The nutritional breakdown of Capsicum is as follows:
Pharmacology : Capsaicin (active component) contains over 100 distinct volatile compounds.3 It also contains capsacutin, capsaicin, capsantine, and capsico. Character: analgesic, antibacterial, antioxidant, antipyretic, antiseptic, antispasmodic, aromatic, astringent, blood thinner, cardiovascular tonic, carminative, circulatory stimulant, diaphoretic, hemostatic, herbal accentuator, nerve stimulant, stomachic and tonic (general) Body Systems Targeted : cardiovascular, circulatory, gastrointestinal, nervous, integumentary, skeletal, metabolic Herbal Forms: loose dried powder, capsulized, tincture, infused oil, ointment or cream Usage : Capsicum can be used liberally in a variety of forms. Capsulized dried Capsicum is probably the easiest and most practical way to take the herb. Commercial ointments can be purchased which contain from 0.025 to 0.075 percent capsaicin for the treatment of pain and psoriasis. Dried Capsicum can be mixed in hot water or can be used in tincture form, which can be added to water or juice. Safety: Capsicum is generally recognized as safe in the United Sates and has been approved as an over-the-counter drug. A four week feeding study of Capsicum concluded, “It appears that red chile is relatively non-toxic at the doses tested in male mice.”4 The seeds of the fresh Capsicum plant should not be ingested. Doses of Capsicum should be followed precisely as prescribed to avoid gast rointestinal upset. Pregnant women or breast feeding mothers should avoid using Capsicum. Initial use of topical Capsicum can result in some skin irritation or burning; howe ve r, clinical tests have found that this diminishes with continued application. Avoid direct contact with eyes or other mucous membranes in general.