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Search Term: " Carnosine "
six top-notch supplements that can help you achieve your goals.   
Date:
December 06, 2023 04:55 PM
If you're looking to stay in the game longer and improve endurance while promoting rapid recovery, we've got you covered! six top-notch supplements that can help you achieve your goals.For most of us, life can feel like quite the balancing act. In an ideal world, we would all have ample time throughout the day to dedicate to our health and well-being. However, reality paints a different picture, where 24 hours can seem like an insufficient amount of time to squeeze in work, school, family, and the countless responsibilities that life throws at us. In recent years, the use of supplements for recovery has gained popularity, becoming more common than ever before. Our bodies face a barrage of daily stresses, including exposure to environmental toxins, electromagnetic pollution, and the strain of intense physical activity. These factors increase our body's demands for antioxidants and essential nutrients that aid in the process of recovery. While consuming antioxidant-rich foods can certainly make a difference, it can be challenging to meet these requirements solely through our diet. That's where a well-rounded supplement regimen can play a crucial role in promoting optimal health and aiding in recovery. Even with our best efforts to exercise regularly, eat nutritious meals, and get sufficient sleep, life in the 21st century can be incredibly demanding, depleting our bodies on a cellular level. For athletes, consistent training is key to reaching desired performance levels. It's important to understand that the muscle recovery and building process primarily occurs between gym sessions. Developing a comprehensive recovery strategy during this crucial window, through the use of supplements, proper nutrition, and adequate rest, can help athletes perform at their best week in and week out. Failing to make the most of this recovery period may result in free radical damage and delayed onset muscle soreness (DOMS). To maximize the benefits, it's important to prioritize food as the primary source of vital nutrients, while also recognizing the significant role supplements can play in providing the necessary building blocks for muscle repair due to their rapid absorption rate. However, it's essential to ensure that any chosen supplements are clinically validated, demonstrating efficacy and supported by solid scientific evidence. In today's fast-paced world, there is a growing demand for quick and convenient solutions to jumpstart the recovery process. Nevertheless, when it comes to choosing supplements, it's important to remember that one size does not fit all. The market offers an overwhelming array of options, often leaving individuals feeling bewildered about which products to select. Before diving into my recommendations for the top six supplements to aid in recovery, I believe it's crucial to emphasize the significance of cellular renewal and its direct impact on the recovery process. This, in my opinion, serves as the key to achieving a quick and effective recovery. Oxidation and Free Radical DamageA fundamental key to staying young and maintaining optimal health is cellular renewal and minimizing the damage to cells over time. We all age, but studies have shown that some individuals age better than others. Have you ever wondered why? Well, recent research has linked oxidative stress to the aging process. So, what exactly is oxidative stress? Allow me to explain in simple terms – oxidation occurs when the body produces by-products commonly known as free radicals. It's almost like a machine rusting, but instead of rust forming on iron, our bodies experience the effects of aging and age-related diseases. Now, our bodies naturally produce free radicals as part of our daily metabolism, and they can also be produced as a result of environmental pollutants from everyday things like air, water, and even sun exposure. As we age, our bodies become more vulnerable to the long-term effects of oxidative stress, which simply means we accumulate too many free radicals and experience increased inflammation at the cellular level. As interesting as it may sound, the process of oxidation is actually abundant and can be beneficial for our bodies to function properly. But, and this is an important "but," this very process can also cause potential harm. You see, the oxidizing process creates these molecules called free radicals, which are electrically charged. These free radicals interact with our cells, and this interaction can lead to both positive and negative outcomes. For example, our immune system utilizes free radicals to help fight infection. However, when LDL cholesterol (often referred to as bad cholesterol) is oxidized, it can become a concern (cholesterol buildup). Let's talk about oxidative stress. It occurs when the level of free radicals overwhelms the body's natural antioxidant defense system, resulting in cell damage. As I mentioned earlier, while free radicals serve useful functions in the body, they are highly unstable molecules. If they remain uncontrolled, they have the potential to wreak havoc by causing damage to cells, enzymes, and even our DNA, which ultimately accelerates the aging process. In addition, these free radicals can also contribute to the development of various age-related diseases, including arthritis, cancer, and heart disease Now, inflammation is triggered by free radical damage, and it is this inflammation that leads to the negative effects of free radicals due to oxidation. The question then becomes, how can we address this in our daily nutritional regimen? The answer lies in the incorporation of antioxidants, which play a vital role in combating oxidative stress and minimizing the damage caused by free radicals in our bodies. You'll be glad to know that there are foods rich in antioxidant content that can help us on this journey. In fact, certain foods contain phytonutrients that, according to many health professionals, hold the potential to unlock the secrets of longevity and overall well-being. So, my dear friend, let's take a proactive approach, nourish our bodies with antioxidant-rich foods, and strive to minimize the effects of oxidative stress caused by free radicals. It's never too late to make positive choices for our health and age gracefully. Phytonutrients, also known as health boosters, are substances produced by plants to protect themselves from harmful bacteria and viruses. However, these compounds also offer significant benefits to the human body. Packed with essential nutrients, phytonutrients play an active role in promoting good health. They belong to the antioxidant family, responsible for eliminating harmful free radicals and thus slowing down the aging process. Incorporating a diet rich in high antioxidant foods like fresh fruits and vegetables is crucial as the first line of defense against aging. While vitamins A, C, and E are commonly known antioxidants, there are other antioxidants available in both food and supplement form. These antioxidant supplements play a vital role in bridging the nutritional gap left by processed foods, lacking the necessary antioxidants and nutrients to combat free radicals effectively. Let's take a closer look at my top six supplement recommendations, known for their efficacy in fighting oxidative stress and promoting optimal recovery: Beta Alanine: As an amino acid derivative, Beta Alanine is proven to enhance intramuscular Carnosine content, improving the body's ability to buffer hydrogen ions. During exercise, the body accumulates hydrogen ions, contributing to fatigue and lowering pH levels. Beta Alanine supplementation can reduce fatigue, enhance exercise performance, and increase training volume. Whether it's interval training or weightlifting to improve running economy, incorporating beta-alanine can have a positive impact on endurance performance and overall training results. BCAAs: Branched Chain Amino Acids (BCAAs) have become a staple supplement for athletes due to their role in muscle and energy production during exercise. Consisting of three essential amino acids - leucine, isoleucine, and valine - BCAAs have been shown to significantly reduce muscle soreness and expedite the recovery process. Supplementing with BCAAs helps prevent muscle breakdown, as the body does not need to rely on its own muscle tissue for energy. Consequently, protein synthesis remains high, supporting muscle growth and repair. Creatine, a natural molecule found in muscle cells. When engaging in high-intensity workouts like weightlifting, Creatine helps your body produce adenosine triphosphate (ATP), a vital energy source. This amazing compound improves strength, boosts lean muscle mass, and aids in faster muscle recovery. Flavonoid Root, a breakthrough extract known for its cardiovascular benefits. This extract is packed with potent antioxidants and acts as a nitric oxide booster, promoting increased endurance during workouts. Studies have shown that it fights against free radical damage and increases the flow of oxygen-rich blood, ensuring optimal cardiovascular health. You can also boost nitric oxide with beet root, and l-citruline. Speaking of studies, a published research paper in Food and Nutrition Research (April 2016) highlighted the effects of the unique flavonoid root extract on arterial health. The study revealed that after one year of consumption, participants experienced a decrease in artery wall thickness, total cholesterol, LDL levels, and blood pressure. This indicates that the extract may help reduce the risk of oxidation-related cerebral vascular issues and improve overall cardiovascular health Glutamine. It's the most abundant amino acid in the human body and plays a vital role in muscle recovery and repair. Glutamine aids in preventing muscle soreness, optimizing post-workout recovery, and supporting muscle rebuilding. By facilitating nitrogen transport, regulating acid-base balance, and acting as an antioxidant, Glutamine ensures faster post-workout muscle recovery, giving you the freedom to train harder for better results. Protein plays a crucial role in replenishing and repairing your muscles after a workout, making it a key nutrient to consume alongside carbohydrates. By opting for a protein shake as a post-workout option, you can efficiently supply amino acids to your muscles, stimulating muscle protein synthesis, enhancing recovery, and promoting growth. It's important, though, to choose a protein shake that contains high-quality ingredients, as prioritizing quality over quantity is key when it comes to protein. Apart from protein, there are several other supplements that work through various mechanisms to provide natural, broad-spectrum antioxidant and nutrient support, ultimately contributing to optimal health and recovery. Taking preventative measures to protect the health of different body systems is much easier than trying to restore their function after damage has occurred. With this in mind, retailers should suggest a preventive program to their customers, aiming to limit free radical damage and promote recovery. As the adage goes, "an ounce of prevention is worth a pound of cure," emphasizing the significance of protecting and preserving one's health. In conclusion, the role of antioxidants, particularly phytonutrients, in maintaining overall health and combating oxidative stress cannot be overstated. These beneficial compounds not only slow down the aging process, but also enhance the body's ability to recover from physical exertion. Various supplements, including Beta Alanine, BCAAs, Creatine, Flavonoid Root, Glutamine, and Protein, each offer distinct benefits in supporting muscle growth, improving athletic performance, and promoting quicker recovery. The incorporation of these supplements into one's regimen can effectively bridge the nutritional gap left by processed foods. A preventive strategy, emphasizing a diet rich in antioxidants and high-quality supplements, holds the key to optimal health and longevity. As the saying goes, 'an ounce of prevention is worth a pound of cure'.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6591) Beta-alanine supplementation relieves fatigue, increases musclecarnosine 
Date:
May 02, 2019 03:37 PM
It has been found in a study that supplementing with beta-alanine can increase muscle carnosine and relieve fatigue. The study was published in the journal Nutrition Research and the team looked at the effects of beta-alanine supplementation on performance, L-histidine, and muscle carnosine in both women and men. This confirms earlier studies that supplementing with beta-alanine increases muscle carnosine, therefore improving the capacity of the muscles to buffer during intense exercise. The research team emphasized their comparison on the differences between women and men, and recruited 26 men and women who were given a placebo or beta-alanine for 28 days. It was shown that beta-alanine really increased muscle carnosine but the differences between men and women were unclear. Key Takeaways:
"The findings of the study suggested that supplementing with beta-alanine for 28 days can increase muscle carnosine and relieve fatigue in men and women, but did not reduce muscle L-histidine." Read more: https://www.naturalnews.com/2019-03-19-beta-alanine-relieves-fatigue-increases-muscle-carnosine.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6246) What Is Beta Alanine And How Does It Improve My Athletic Performance?
Date:
January 16, 2014 05:32 AM
Beta-alanine is classified under non-essential amino acid; which imply that the body is able to produce. Amino Acid Amino acids are the building components of proteins. Beta-alanine is a precursor to the compound Carnosine; which, functions by regulating the acidic environment resulting from active muscles. In a case where the cellular environment inside the muscle becomes too acidic, then the muscle ceases to function. To prevent this Carnosine slows down or attenuates the development of an acidic environment allowing an athlete to perform better or exercise with more work load. What is Carnosine Carnosine is very effective at controlling the hydrogen ions that cause then negative effects of lactic acid. Carnosine is understood to be one of the main muscle buffering substances contained in skeletal muscle. Therefore when Carnosine prevents the arising of an acidic environment which characterizes a high-intensity exercise, the athlete is able to exercise at high intensities for a longer period. When Carnosine is ingested directly through the mouth it is rapidly converted into beta-alanine and histidine by the enzyme carnosinase as soon as it enters the blood stream. It is thus ineffective when Carnosine is ingested directly. However,separate ingestion of beta-alanine and histidine results in these two compounds re-conversion to Carnosine after absorption into the skeletal muscle. Beta-alanine has great benefit in improving athletic performance and exercise intensity, and the building of lean muscle mass. Research indicates that beta-alanine is the amino acid that highly affects intramuscular Carnosine amount as it is the rate-regulating substrate in this chemical reaction (Dunnett and Harris 1999). Recommended Use for Beta Alanine It is highly recommended that beta-alanine be taken in daily dosages in order to be highly effective, with dosage amounts varying from different expert opinions as well as dependant on the athlete preference. Studies have indicated that 28 days dosage of 4 to 6 g/day of beta-alanine supplementation resulted in an approximately 60% improvement of intramuscular rates (Harris et al. 2005; Zoeller et al. 2007) References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2966) Can L-Carnosine Be Used As An Anti-Aging Vitamins?
Date:
April 18, 2012 07:31 AM
Carnosine And Your Health Carnosine has gained widespread popularity as an anti-aging compound despite some skeptical voices in the scientific community. Many studies lend credence to its value for treating the signs of aging and its antioxidant properties are well researched. Carnosine is also widely used as a supplement to prevent complications from diabetes such as nerve and kidney damage. This article will discuss the details of what it is, what it seems to do in the body and how it may be able to help people restore a more youthful state of health. Discovered in Russia more than a century ago, Carnosine is an amino acid and is found primarily in muscle, skeletal and nervous tissue (including the brain). As such the primary dietary sources are animal products such as fish, poultry and red meat. It is common for vegetarians to become deficient in it, making them ideal users of Carnosine supplements. Glycation There is a gradual decline in Carnosine levels as we age, which lends credence to the claims of its anti-aging properties. The most clearly established property of Carnosine is its ability to act as an anti-glycation agent. Glycation is a process the body goes through to release energy from sugar but which ends up producing harmful substances. Carnosine can neutralize some of these already formed substances and also prevent the process from forming new ones. Some researchers believe glycation may be the key behind the benefits of caloric restriction, making Carnosine the long awaited magic pill that can mimic its effect as a longevity treatment without the deprivation of restricting food intake. Antioxidant Properties In addition to Carnosine's anti-glycation effect, it also has antioxidant properties. The oxidation process which the body goes through naturally produces the well known "free radicals" which slowly damage the cells and are thought to play an important role in the aging process. Carnosine can neutralize this protecting the cells. This also has a beneficial effect at keeping the telomeres from shortening, which is thought to be the main cause of the aging process. Telomeres are the buffers at the ends of DNA code that protect the code from being corrupted, so when the telomeres become shorter there is less protection and a greater chance of things going wrong. This makes Carnosine's protective benefits of great importance in the fight against aging. Carnosine Protects The Cells From Damage Like Radiation Studies show that Carnosine can protect the cells from radiation damage, which is particularly useful for cancer patients who have to undergo radiological treatment. It also promotes the healing of wounds and protects cell membranes. Some studies demonstrate that it can literaly repair old cells and make them younger. As it binds easily to toxic metals, turning them into powerful antioxidants, it is very effective at protecting the body from their harmful impact. Some of the most promising uses of Carnosine are for the treatment and prevention of Alzheimer, the signs of aging in the skin, cataract, nerve and kidney damage and heart disease. The recommendation for use as a supplement is 500 miligrams, though the body can deal safely with much larger doses. Give Carnosine a try today and experience the difference yourself.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2636) What Is L-Carnosine And What Does It Do?
Date:
March 30, 2012 08:28 AM
What Is L-Carnosine L-Carnosine is basically a combination of 2 vital amino acids-L-histidine and beta-alanine. It is naturally present in the body, mainly in the muscle, and in many animals too. Carnosine can be broken down easily into the two amino acids, but it is good to know that these amino acids work much better when combined to form L-Carnosine. L-Carnosine has the remarkable ability to revitalize, that is, to make older cells younger and lengthen their life cycle. This compound is commercially available and is the only one that has the rare and distinctive ability to rejuvenate cells. What does L-Carnosine do? In simple language, L-Carnosine is able to transform itself into so many compounds with each performing or enhancing a number of crucial body functions such as: May bind to dangerous metal compounds to make them inactive. Turning the resultant metal compound/Carnosine into useful antioxidants which in turn can be anti-ulcer agents Protecting and stabilizing cell membranes, keeping cells safe from dangerous free radicals Protecting healthy cells from damage caused by radiation Fighting allergies Enhances blood flow to the brain Acts like a neurotransmitter, helping messages move from one nerve to the other. This helps fight dementia, as in Alzheimer's disease and Parkinson's disease, and boost memory. Blocks guanylate cyclase activation, an enzyme associated with cancer, migraine, asthma, and septic shock. Special derivatives of Carnosine can help get rid of the accumulation of sugar compounds and abnormal protein in the eye. A variety of these compounds may cause glaucoma, cataracts, and macular degeneration. Carnosine works like a catalyst to boost the work of so many other compounds and nutrients. Benefits of using L-Carnosine Although L-Carnosine benefits haven't been extensively researched, according to initial studies it may help in: Dealing with complications related to cataracts, diabetes, neuropathy, and kidney failure. It may also help in slowing down aging in skin, minimizing wrinkles as well as breakdown of elasticity in skin. It can help to prevent joint inflammation, atherosclerosis, and formation of cataract. Carnosine has been known to prevent and reduce cell damage occasioned by beta amyloid-the substance found in Alzheimer's patent's brain. Additionally, Carnosine appears able to help get rid of the helicobacter pylori bacterium, the organism associated with stomach cancer and peptic cancer. Therefore, it can significantly help protect and heal both peptic and gastric ulcers. Other possible L-Carnosine benefits Increase muscle endurance and strength Improves heart function Speeds healing of wound A powerful antioxidant that can deal with even the worst free radicals Reduces inflammation and boosts immunity It helps pull out or chelate some heavy metals from your body May help autistic children Act as anti-cancer agent in the body Stabilizes cell membranes and slows down lipid peroxidation to protect the process of aging of the brain L-Carnosine can help in preventing or even treating age-related conditions like: Cell aging/cellular senescence Neurological degeneration Cross-linking of eye lens Build up of damaged proteins Brain circulatory deficit Muscle atrophy Cross-linking of collagen in the skin DNA chromosome damage LDL cholesterol oxidation Formation of AGEs i.e. advanced glycation end-products. What is stopping you from taking L-Carnosine today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2623) What Are The Health Benefits Of L-Carnosine?
Date:
February 28, 2012 07:53 AM
L-CarnosineAmong the numerous natural compounds in the body, L-Carnosine is also one such beneficial compound that is naturally contained in the human body. Numerous health benefits are offered by this compound, and it plays an integral role in maintaining the wellness of an individual. However, as people begin growing old, are frequently stressed or have undergone some sort of a trauma, then the levels of this compound in the body are decreased. What is L-Carnosine? This compound is basically a dipeptide that comprises of alanine and histidine, which are two different types of amino acids. The brain, heart, kidneys, muscles, skin and the stomach are the organs where L-Carnosinecan be naturally found. Due to its potent antioxidant traits, this dipeptide is regarded as an effective anti-aging agent. What Are The Health Benefits Of L-Carnosine? As mentioned, Carnosine is an integral dipeptide in the body and quite an array of benefits are offered by it. Due to the intense antioxidant qualities of L-Carnosine, the free radical damaged caused within the body is minimized. Free radicals are not good for the cells present in the body since they damage and kill cells, and can also alter DNA too. Thus, Alzheimer's disease, heart disease, cancer and skin damage, are some of the health problems people can suffer from as a result of altered DNA, damaged and dead cells due to free radicals. In comparison to vitamin E, this compound can protect cell membranes from oxidation more effectively because it is water-soluble. Other Carnosine Benefits The compound also helps in healing wounds as well. The connective tissues in the body are effectively repaired thanks to the antioxidant qualities of Carnosine, and the skin is ideally healed. The compound also helps reducing the risk of wound infection too. Cataracts and other eye conditions can also be relieved with the help of the health benefits offered by this compound. Even though this compound is naturally contained in the eye, however, as people get older, its amount lessens. Thus, primary and mature senile cataracts can be effectively cured with eye drops containing L-Carnosine. Even the heart is kept healthy by this compound as well. The heart tissue muscle is strengthened by this compound and enzymes that enable the heart muscles to contract are also activated by it. How to Increase the Level of L-Carnosine in the Body? Those who want to increase the amount of this beneficial dipeptide in their body should eat a diet that essentially includes fish, meat and poultry. Dietary supplements can also supply the body with this compound. L-Carnosineis contained in certain multivitamin supplements, which contain various other amino acids, minerals, vitamins and other special nutrients. Thus, the overall positive effective of this compound in the body can be further enhanced by taking such supplements. As long as the supplement being used contains nothing but natural ingredients, supplementing this compound in the body can help an individual avail many health benefits. L-Carnosine is, therefore, an important dipeptide and those who are growing old should consider supplementing it through diet or supplements.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2595) Fight Heart Burn
Date:
April 18, 2008 11:38 AM
In a search to promote a long and healthy life, a lot of Americans forget about their stomachs, which results in things ranging from simple heartburn to ulcers and even cancer. The effects of alcohol, smoking, and stress added to the rate of infection create the perfect conditions for stomach distress and disease. A combination of four nutrients: zinc, Carnosine, licorice extract, and cranberry, work together to protect stomach function from the environment. These nutrients not only relieve distress, but they also support the body’s natural defense mechanisms against inflammation and the changes that can lead to cancer. A fifth nutrient, picrorhiza, protects the mucosa and can now be included as part of a natural gastric health remedy. The human stomach, with its extreme acidity, provides a primary defense against infection and also helps in the first stages of digestion. A thick coating of protective mucus is steadily secreted by the surface mucous cells in the stomachs lining to continually protect its self from Hydrochloric acid. Almost everyone has experienced some kind of “upset stomach”, which we associate with overindulgence foods and stress. Although these are only thought of as mild annoyances, each episode causes a bit more lasting damage, which eventually results in cellular injury, which in turn causes inflammation. This inflammation then produces free radicals, which go on to create more tissue destruction and eventually damage DNA, thus potentially leading to cancers of the stomach worst case. Many natural substances have been used around the world for thousands of years to promote stomach health. Modern science is finding that some of these “folk remedies” actually have potent effects on boosting immunity, reducing inflammation, and simply improving physical protection of the stomach lining. Zinc, a micronutrient that has multiple functions in human biology, mainly functions as a defender against free radical damage. It has been found that the more severe the inflammation in people is directly related to lower levels of zinc in individuals. Zinc also helps to stabilize the membranes of cells that release burst of inflammatory cytokines when they are stimulated by injury or allergy. This mineral is also a well known immune modulator, which can reduce the recurrence rate of certain inflammation-sensitive cancers. There’s no doubt that zinc is a potent anti-inflammatory, and gastroprotective nutrient, but when it is added to amino acid Carnosine, these effects can be boosted even further. Certain fruits, cranberries particularly, are rich in anthocyanins, which have extreme antioxidant abilities. Other compounds that are found in cranberries also prevent bacteria from settling in the urinary tract. A review by nutritional experts found that regular intake of cranberry juice and other dietary products may be an alternative solution for those people who are at risk for H. pylori colonization. It also seems as though cranberries and there extracts can be placed alongside zinc-Carnosine as an important component of an effective stomach health regimen. Licorice extracts have also been shown to help fight stomach infection. Various studies have found that these extracts have potent anti-inflammatory activies, as they reduce cytokine production and increase the protection of the protective stomach mucus. These characteristics, when placed alongside those of zinc-Carnosine and cranberry extracts, provide hope that a basis for an alternative therapeutic agent fighting H. pylori can form. Picrorhiza, which is already used to speed healing in other infections such as hepatitis A, demonstrates unique wound-healing properties, stimulating tissue growth, nerve cell recovery, and blood vessel formation. Even though the multi-armed approach to gastric protection and improved stomach health seems to be complete with zinc-Carnosine, cranberry, and licorice extract, picrorhiza extract brings together the infection-fighting, anti-inflammatory, antioxidant, and tissue-healing capabilities of multiple compounds, which all have complementary actions. If you’re looking for a alternative approach to boost stomach health, the vitamins and herbs listed above are a great starting point. Please do not discontinued prescription medication from your doctor, some cases of stomach issues must be consulted with your doctor before discontinuing use.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1762) Alpha Lipoic Acid is a Powerful Antioxidant
Date:
February 15, 2008 02:55 PM
The discovery of alpha lipoic acid at the University Of Texas Chemistry Department in 1951 was not heralded with trumpets of joy at the revelation of such a powerful antioxidant, but was instead largely ignored. This is largely due to the biochemistry involved not being fully understood at that time, but by the 1980s it was a commonly used supplement, recommended for several medical conditions. Chemically, the substance is a 5-membered cyclic disulphide with a carboxylic acid grouping. Biochemically, it’s extremely powerful antioxidant properties are largely due to the fact that it one of those rare active molecules that are soluble in both water and fats, and in fact is the only such antioxidant currently know. One of the properties that this ability enables it to possess is to cross the blood-brain barrier, and apply antioxidant propertied to the brain. Antioxidants are essential to human life in that they destroy free radicals. These are compounds with free unpaired electrons that destroy human body cells in their hunt for electrons to pair with. Electrons come in pairs in organic animal tissue, just as they do in organic compounds. However, under certain circumstances this pairing can become destroyed, leaving a molecule with one of its electrons without a partner. The factors that lead to this situation are many and varied, and our own biochemistry can produce free radicals during the normal chemical processes of life. However, pollution can also lead to the oxidation processes that create free radicals, common such pollutants being cigarette smoke, vehicle exhaust fumes, pesticides and the like. Excessive exposure to the UV content of sunlight can also create free radicals as can eating barbecued and smoked foods, and exposure to carbon monoxide and peroxides. Even the biochemical conversion of glucose to energy in our bodies creates free radicals. These free radicals can destroy body cells, including DNA, and can create conditions such as premature aging due to destruction of skin cells, destruction of brain cells, strokes, cancers, diabetes, atherosclerosis due to oxidation of LDL cholesterol that deposits in the main arteries of the body, stiffening of the joints and many other undesirable conditions. Free radicals are destroyed rapidly by antioxidants: the reaction is very rapid and most are destroyed immediately they are formed before they can do harm. Fortunately, if your diet is well maintained, the body possesses many antioxidants such as vitamins A, C and E, and other substances such as Coenzyme Q10, flavanoids, xanthenes, polyphenols and carotenoids. Many of these are found in highly colored foods, and if your food is brightly colored, it should contain a good supply of antioxidants. However, the problem with all of these is that they are either fat and oil soluble or water soluble, which means that they can either be freely carried round the body by the blood or have to be emulsified by the bile and transported via the lymphatic system that places restrictions on their effectiveness in certain organs of the body. The fact that alpha lipoic acid is soluble in both water and fats enables it to be carried to all parts of the body and to every organ, and can cross water/fat barriers that other antioxidants cannot do. It can therefore be carried via the blood to the brain and carry out an essential antioxidant function within our brains. It took a long time for this property of ALA to be recognized and its consequent health benefits understood. It is, in fact, the ideal antioxidant. The substance provides many known benefits to the body due to its antioxidant properties and also helps the body to generate the maximum possible amount of energy from the blood glucose and thus improve the energy balance of your body. However, it is with its antioxidant properties that we are most concerned here. One of the benefits of these properties is its effect in holding back the visible effects of aging on your body. Because it is both water and fat soluble, alpha lipoic acid can help destroy free radicals in every part of your skin; the areas served by the blood and the fatty and oily secretions are protected simultaneously by the same strong antioxidant. The end result is a reduction in the destruction of the cells through the dermis and epidermis and a reduction in the degree of wrinkling with age. Its antioxidant effect in the brain renders ALA in great demand for reducing cognitive impairment with age. In fact studies have indicated that alpha lipoic acid can improve memory and brain function in the aging and the elderly. This effect appears to be increased by the synergistic combination of alpha lipoic acid and acetyl-L-carnitine that work together to prevent cognitive decline in the brain through the effect of free radicals. There is evidence that during a stroke, ALA works synergistically with vitamin E to reduce the effect of free radical damage on the vulnerable brain cells, and so reduce the longer term effects of the stroke. Together with ALC, it also reduces oxidative stress on the mitochondria of cells and in so doing helps once again to reduce the effects of aging, and maintain the body’s capacity to generate energy from blood glucose. Cardiovascular disease is the main killer of the western world, largely due to our diets, and this is especially true of the USA. Although Americans appear unable to change their unhealthy diet, alpha lipoic acid and acetyl-L-carnitine can be used to offset much of the damage done. ALA reduces the development of atherosclerosis through its antioxidant properties and the reduction of the adhesion of monocytes to the artery walls. LDL trapped in the wall of the artery can be oxidized and enable monocytes to also enter under the surface of the arterial wall, where it changes into macrophages and ingests the oxidised LDL, causing the plaque that forms atherosclerosis. As the plaque thickens, the artery becomes increasingly restricted until the blood flow is significantly reduced or even stopped, causing cardiac failure or a stroke. Alpha lipoic acid can prevent this free radical oxidation from occurring by destroying them before they act on the low density lipoprotein (LDL). Acetyl-L-carnitine works with the ALA to achieve this, as does another substance known as Carnosine. Between them, these three musketeers work to keep your arteries clear and your brain functioning as it should, though it is the ALA that is most powerful due to its oil and water solubility properties. Although alpha lipoic acid is available as a supplement, either alone or in combination with acetyl-l-carnitine, it is also available from natural food sources. It is particularly rich in offal such as heart and kidney, and also in broccoli, spinach and brewer’s yeast. It is also available in beef, and it is here that burgers can perhaps repay some of the damage that it causes. However, it is not a recommended source since burgers still cause more damage to your health than any of their constituent nutrients can allay. Like any other supplement, you should seek medical advice before taking any substance if you have a health condition. Nevertheless, the benefits of alpha lipoic acid are such that it is difficult to see it doing anything but good. However, please consult your physician if are taking other drugs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1718) Life is more enjoyable when your stomach is prepared for it.
Date:
November 28, 2005 12:05 PM
-- Help the stomach at Vitanet
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=965) PepZin GI™ helps relieve occasional discomfort.
Date:
September 20, 2005 05:40 PM
PepZin GI™ helps relieve occasional discomfort.* CLINICAL TRIALS In a randomized, multi-center, placebo-controlled double blind study, 299 patients suffering with symptoms of gastric discomfort were randomly allocated to receive either a zinc-L-Carnosine complex or a placebo, or a control drug or its placebo for 8 weeks. Improvement ratings for a range of symptoms were taken at various points during the trial and compared with before treatment data. Of the 258 people who completed the trial, 136 were in the zinc-LCarnosine group. Of the group, 92% of the participants were rated as “moderately improved” or better on an improvement scale across the category of symptoms including heartburn, tenderness, epigastric pain, diarrhea and constipation after 8 weeks.3 In another study, 28 patients with gastric discomfort were given a zinc-L-Carnosine compound and monitored for 8 weeks. Improvement was rated on a scale of subjective and objective symptoms. After 4 weeks, the rate of those cases that were considered to be “significantly improved” was 68.4%. After eight weeks, the “significantly improved” number was 68.8%. Over 60% of these patients remained in the “significantly improved” category well after discontinuation of the treatment, suggesting a lasting effect of the zinc-L-Carnosine compound beyond the time it is taken.4 Maintains a healthy GI environment.* The mineral zinc in PepZin GI™ is a critical component to a number of physiological processes in our bodies. Some of these functions include growth and metabolism of cells, healing of wounds,and maintenance of carbohydrate and lipid metabolism.2 PepZin GI™ may also be able to favorably maintain the bacterial balance of the stomach and GI tract. Studies suggest that the zinc-L-Carnosine co m pound may have effects on certain strains of harmful bacteria and, therefore, may be able to help maintain a GI environment that is favorable to health.1 By supporting the bacterial balance in the stomach, PepZin GI™ can help maintain a healthy mucosal lining. Supports the health of gastric cells.* PepZin GI™ has been studied for its ability to prevent free radical damage to gastric cells. In one such study, rat gastric cells were exposed to ethanol and hydrogen peroxide, two substances known to cause free radical damage to living cells. Cells were bathed in hydrogen peroxide, ethanol, zinc-L-Carnosine, or a combination of zinc-L-Carnosine with either ethanol or hydrogen peroxide. While the cells bathed in ethanol and hydrogen peroxide solutions all exhibited signs of damage due to free radical production, the cells that were bathed in zinc-L-Carnosine were largely protected from the effects of free radical damage. The authors concluded that the zinc compound directly protected gastric mucosal cells from oxidant stress and alcohol induced damage.5 Additional research further confirms the gastro-protective effects of PepZin GI™. In another rat study, stomach lesions were induced by administration of the chemical monochloramine, a known pro-oxidant (producer of free radicals). One of the groups of rats was fed the zinc-LCarnosine compound prior to being exposed to monochloramine. The researchers found that the size of the lesions in the group pre-treated with zinc-L-Carnosine was significantly less than the lesions in the control group. The authors concluded that the zinc compound exerted a beneficial protective effect against monochloramine-induced stomach lesions.6 The zinc-L-Carnosine in PepZin GI™ has also been shown to slow the development of aspirin induced stomach damage in rats. The researchers measurably detected lower levels of TNF-alpha in rats given zinc-L-Carnosine as compared to the control rats. TNF-alpha is an inflammatory cytokine that is known to be released in response to gastric damage.7 These results may suggest a role for PepZin GI™ in protecting gastric cells by occasionally reducing the levels of certain cytokines in minor inflammation of the stomach. Scientific References 1. Kuwayama H, et al. Polaprezinc. Nippon Rinsho 2002 Feb; 60 Suppl 2:717-720. 2.Matsukura T,Tanaka H. Applicability of zinc complex of l-Carnosine for medical use. Biochemistry (Moscow) 2000;65(7):817-823. 3.Miyoshi A, et al. Clinical evaluation of Z-103 on gastric ulcer - a multicenter double-blind comparative study with cetraxate hydrochloride. Jpn PharmTher 1992;20(1):199-223. 4.Misawa T, et al. Clinical study of Z-103 - clinical effects on gastric ulcer and influence on endocrine function. Jpn PharmTher 1992; 20(1):245-254. 5. Hiraishi H, et al. Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacl Ther 1999;13:261-269. 6. Kato S, Nishiwaki H, et al. Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate. Dig Dis Sci 1997;42(10):2156-2163. 7.Naito Y, et al. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis Sci 2001;46(4):845-851.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=792) NEW PRODUCT ANNOUNCEMENT
Date:
July 05, 2005 06:29 PM
The Most Comprehensive Antioxidant Formula Available!
Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
gamma-Vitamin E Complex 500 mg
Quercetin 100 mg
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=548) RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available 
Date:
June 24, 2005 05:34 PM
The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers. Bio-Aligned Antioxidant Support RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA. Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen. Healthy Heart Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support. Nourishing the Brain Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support. Liver Support Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E. Immune Defense The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense. Skin & Connective Tissue Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C. Clear Vision Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes. Energy Generation Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration. DNA Protection DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and Carnosine. In in-vitro studies, L-Carnosine reduced glycation, a process in which DNA and protein are damaged by glucose. Living Longer, Living Better Strategies for Wellness
Wellness Revolution Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today. References Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868. Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf
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Beta alanine
