Search Term: " Closer "
Vitamin E: A Closer Look at Tocotrienols
October 21, 2017 10:14 AM
Researchers have made an estimate and guessed that there are 75 trillion cells in the body. Each of those cells is surrounded by a membrane that is bean shaped. This membrane is made up of dense rows of fatty acids. These require protection from lipid peroxidation. Vitamin E is one of the popular antioxidants. Vitamin E is shaped like a tadpole, which is the perfect shape to do this job. There are two forms of Vitamin E.
"In this study, researchers found that alpha-tocopherol, when co-administered with tocotrienols, reduced tocotrienols’ inhibitory effect on HMGR."
Read more: http://www.nutritionaloutlook.com/vitamins-minerals/vitamin-e-closer-look-tocotrienols
Lutein, found in leafy greens, may counter cognitive aging
July 31, 2017 12:14 PM
A website that reports on science news has an article summarizing a scientific study about lutein. This is a substance found in leafy green vegetables such as spinach and kale. A university study was conducted on subjects in the age 25 to 45 range. The study found that those subjects who had higher levels of lutein were neurologically closer to younger people. The article cited its source and included a link to the study. A photo of an avocado smoothie is included.
"The study, which included 60 adults aged 25 to 45, found that middle-aged participants with higher levels of lutein -- a nutrient found in green leafy vegetables such as spinach and kale, as well as avocados and eggs -- had neural responses that were more on par with younger individuals than with their peers."
Read more: https://www.sciencedaily.com/releases/2017/07/170725122004.htm
CONFIRMED: Omega-3s boost blood flow to regions of the brain responsible for learning and memory
June 02, 2017 12:14 PM
A new study finds an increase in blood flowing to your brain, and it may help to prevent cognitive disorders such as Alzheimer's. Alzheimer's disease is a leading cause of death, causing a downward deterioration of a person ability to live independently as the symptoms become worse. The study shows correlation between omega-3 concentrations in the brain with a lower incidence of brain disease, called neurocognitive disorders. The omega-3 is found to be the cause of increased blood flow to the brain, resulting in a decreased probability of neural degradation.
"This study opens the door to the possibility that relatively simple dietary changes could favorably impact cognitive function."
Read more: http://www.naturalnews.com/2017-05-25-confirmed-omega-3s-boost-blood-flow-to-regions-of-the-brain-responsible-for-learning-and-memory.html
Cannabidiol bill for epileptic seizures moves closer to becoming law
April 14, 2017 11:44 AM
Author Janet Williams writes about a bill in Indianapolis that would further the usage of medical marijuana for use among patients with epilepsy. The article lists the how the votes were cast and which side they favored. The author also makes a point to mention that the medical marijuana would be high CBD product rather than the typical form which contains majority THC, meaning that the medical product would not be for "getting high", but in fact would be medicine for epilepsy treatment with no psychoactive properties.
"Cannabidiol, or CBD is found in the seeds, stalk, and flowers of cannabis plants like hemp and marijuana. CBD has been found to minimize seizures in epileptic patients and has a negligible level of THC, the compound that creates the “high” feeling in marijuana."
Read more: http://thestatehousefile.com/cannabidiol-bill-epileptic-seizures-moves-closer-becoming-law/30969/
Benjamin Hardy: 8 Things Every Person Should Do Before 8 A.M.
March 20, 2017 01:44 PM
Getting out of survival mode should be the top of everyone's list. The way to get out of survival mode is to simply do the things on this list. The first is to get a health amount of sleep - at least 7 hours. Next is to either use prayer or meditation to start the day off in the zone. Performing a hard workout and then consuming a breakfast full of protein is next on the list. A cold shower follows, then reading or listening to something uplifting. And finally, review your life goals and then do something that continues you on the path to completing those goals. Doing all these things before 8am will surely get anyone on the path to feeling better about life.
"Sadly, most people’s lives are filled to the brim with the nonessential and trivial."
Read more: http://www.huffingtonpost.com/entry/8-things-every-person-should-do-before-8-am_us_58c808a1e4b03400023f4b68
Rewires Your Brain and Slashes Anxiety Levels, but Beware
March 14, 2017 03:59 PM
Thedocumentary, Ride the Tiger: A Guide Through the Bipolar Brain, focused on current concepts treatment. Drugs available don't work in all patients and lifestyle changes are recommended when possible. It's recommended that bipolar patients and people suffering from other disorders There has been some positive outcomes from devices using light and magnets to stimulate the brain but a healthy diet, exercise, vitamin supplements and probiotics can address these disorders. Patients have also received benefits through exercise and proper sleep patterns. Doing all this, patients have found they can slowly get off their drug treatment regimens.
""By seeking to understand how the bipolar brain malfunctions, researchers believe they can get Closer to understanding the inner workings of the brain, potentially unlocking treatments for other types of psychiatric problems as well.""
Is Pineapple Acidic and Can Pineapple Cause Acid Reflux?
February 27, 2017 10:59 AM
If you suffer from acid reflux, you probably go out of your way to avoid overly acidic foods. However, there is much debate on where pineapple lands on the pH spectrum. Pineapple is indeed acidic, but it also contains bromelain, which has been known to fend off acid reflux. It may still cause acid reflux in those more sensitive to acids, but pineapple usually has an alkalizing effect on stomach acids. If you are willing to give it a try, pineapple has some great health benefits that include a low calorie count and moderate levels of essential vitamins and minerals.
"But for those unaffected by acid reflux, pineapple is an excellent source of vitamins and minerals to keep the body running smoothly."
A Closer Look at Vitamin A
January 07, 2017 07:59 AM
Vitamin A is one nutrient that does not he the attention it deserves. Many people do not get as much as they need, so supplementing may be necessary. It is fat soluble, and it is one of the strongest antioxidants available to the human body. It helps protect many functions of the body.
"Listed here are 5 essential features about vitamin A and why we particularly want it in our day by day food regimen. - See more at: //newsjor.com/a-Closer-look-at-vitamin-a#sthash.3AH2JbhJ.dpuf"
Fight your sickness by making your own DIY all-natural cough syrup
December 29, 2016 02:59 PM
Most people get sick during the winter months although it's not the cold weather that actually makes you sick. People don't go out as much during the winter and are around others more which makes it easier for the bacteria and viruses to spread. Eating healthy, drinking enough filtered water and getting enough exercise are among some of the things you can do to keep your body healthy.
"Most germs that cause the common cold spread more quickly in cold, dry air. Furthermore, during the winter months, people spend more time indoors and Closer to each other, which makes it easier for the bacteria and viruses to spread."
Replacing carbs with protein? Don't overdo it
December 17, 2016 07:59 AM
Protein has become the dietary supplement that everyone is talking about. With benefits thought to range from building muscle to losing weight, protein powders and bars have become a staple in American society. Specialists are beginning to wonder if getting too much protein in the diet can lead to bad side effects. It is estimated that most American men consume double the daily recommended intake. There are concerns that high protein diets can lead to the development of diabetes and liver disease. They are cautioning people to keep their intake Closer to the recommended dosage.
"A canned protein drink can contain almost as much protein as a 227g steak, and snack bars or a small bag of protein chips can pack more of the macro-nutrient than a three-egg omelette."
Are your storable foods mostly just reprocessed GMO corn?
December 08, 2016 08:59 AM
Stocking up on non-perishable foods seems like an intelligent concept on the surface. But upon Closer examination, it may prove that they stored food you buy contains genetically-modified organisms and additives that are toxic to your system. Transgenic corn, corn startch and high-fructose corn syrup are widely used in storable foods, but are nto organic products and are derivatives of "Frankencrops." Many popular brands that sell packaged food use these subtances to increae the shelf life of the food, but the presence of these chemicals in concerning.
"not all storable food is the same, and that much of it is actually loaded with things you probably wouldn't want to feed your families"
10 Reasons to drink lemon water on an empty stomach
November 08, 2016 12:59 PM
Lemon water is a nutrient powerhouse that some celebrities swear by. It is thought that lemon water ingested right away in the morning not only hydrates your body, but it also provides essential vitamins that help jumpstart your day. Everything from the enzymes to the antioxidants present in lemons does a great job of boosting most systems in the body to start the day off right. This simple drink can help detoxify the skin and curb hunger, while also providing some energy and bolstering the immune system.
"According to some health advocates, drinking lemon water on an empty stomach takes you one step Closer to optimal health."
11 Foods that Help You Sleep Better
November 04, 2016 04:09 PM
Did you know that there are some foods that actually help you sleep better? If you are like most people, sleep is a very expensive luxury to come by now a days but with these eleven foods you can help sleep better. These foods are rich in both magnesium and in tryptophan which can help promote not only sleeping quicker but also a more restful sleep. To learn more, please take a Closer look into this article.
"Magnesium regulates circadian rhythms, so you get sounder, more satisfying sleep. Dark chocolate is a great source of magnesium, as are a multitude of other foods we've highlighted below."
Are You Gaining Weight For No Reason? Check Your Thyroid
The human body is an extremely complex system of checks and balances that's held in a very delicate state of equilibrium. It's hard to understand at times but with the patience of science, we can usually get to the bottom of whichever mysteries our bodies will present us with.
One of the mysteries that some people might find themselves faced with at some point in their lives is that of gaining weight for no reason. Diets and exercise will seem not to work. A possible culprit might be found in a small organ known as the thyroid gland. Let’s have a Closer look at it and how it may be affecting your metabolism and weight.
How the Thyroid Gland Works
The thyroid is the largest gland in your endocrine system of glands and is located right in the middle of your neck just below the Adam’s apple in men. Endocrine glands refer to glands that secrete hormones in the human body. The thyroid gland produces the hormones Thyroxine and Triiodothyronine, which are referred to as the thyroid hormones. These hormones play a significant role in your energy regulation and metabolism functions by prompting almost every cell in your body to increase its activity. This is essentially what your metabolic rate is. There are three basic categories of problems that can occur in your thyroid gland, as follow:
The Thyroid Gland and Weight Gain
When too little thyroid hormone is being produced in a patient, their metabolic rate will slow down, meaning that the body’s cell will not be burning up calories at their optimum rate. This will lead to these unspent calories being deposited throughout the body in the form of fat. The person affected might find themselves suddenly gaining weight without any apparent changes in their lifestyle or eating habits. This is also why dieting and exercise may not have the desired effect on the patient.
The symptoms of an underactive thyroid can be very vague because the hormone acts throughout the body but should you find yourself experiencing some of these, consider testing specifically for hypothyroidism:
Check Out The Wonder Grain: Amaranth
February 02, 2014 07:48 AM
The wonder of amaranth
The wonder grain Amaranth has been known to humans for centuries. It was heralded as a staple in the diets of pre Columbian-Aztecs who heralded the plant is granting them special powers. Unfortunately, when the Spanish Conquistadors arrived in the region, they outlawed the crop and went to great lengths to push its existence far from common knowledge. It has only resurfaced on the market in recent decades.
A broad and bushy plant, amaranth can grow to around six feet in height. It sports a bright and colorful flower head which contains an immense amount of seeds. It is not uncommon for a single plant to produce seed quantities around the 60,000 mark. The seeds are typically used in the creation of amaranth cereal or flour.
The plant itself is not technically a grain, belonging instead to the same plant family as beets, spinach and quinoa. This classification is the reason it offers nutritional benefits that are Closer to those offered by darker, greener plants with more foliage rather than those of true grains. Amaranth plays host to a myriad of different nutrients, including vitamins, minerals, and amino acids. One amino acid in particular, lysine, which is generally present in fairly low levels in other grains, appears in a noticeably higher concentration here. Compared to wheat, Amaranth also carries four times as much calcium and double the content of iron and magnesium. It also boasts an exceptionally high level of protein.
Uses of amaranth
This miracle plant can be prepared with a wide variety of techniques. It can be simmered to produce a consistency not unlike porridge. It can also be mixed with other grains to create a dish that resembles rice. Traditionalists can also toss the grains in a skillet to be cooked like popcorn, producing a crunchy, almost nutty experience. While still not yet immensely popular and therefor sometimes harder to find, amaranth can be an excellent addition to any healthy diet.
Bitter Orange Extract
November 22, 2012 10:46 AM
Indigenous to the Meditteranean region today, but brought to their shores by Arab tradesmen in 1200 , bitter orange or citrus aurantium was highly popular among herbalists all over the southern parts of Europe is mainly France, Greece, Spain and Italy. A botanical species commonly termed as seville orange and bigarade orange, this bitter citrus fruit is known for its oil extract, flavoring and use in the perfume industry.
However , the ancient Chinese used it for treating dyspepsia , abdominal distention and diarrhea. These uses also drew from its roots in ancient Greek experiments in aromatherapy, phyto-therapy and cosmetology. Its arrival in America can be credited to the Spaniards and the Portuguese who for very long had been using the fruit for its medical component. Bitter orange trees grew in abundance in the states of Florida, Louisiana and California way back in the middle of the nineteenth century.There have been numerous pharmacological indicators in the study of C aurantium actions and it has been termed as an anti spasmodic, anti fungal , anti bacterial, anti-inflammatory, sedative, tranquilizer and also a vascular stimulant.
Recent studies about its effect on cancer cells is underway. A Closer Look At Its Health Benefits Bitter orange peel, flower and seed are known to have varying effects on the human body and its studies date back centuries. Quite simply it has the ability to squeeze blood vessels, affect the heart rate and also change the level of metabolism. A Closer look at its components would help focus on their particular impact on health.
It results in faster metabolism, increase in heart rate by affecting the adrenaline system, and in turn aid in weight loss. What needs to be seen is whether this metabolism booster is in any way a retardant with any other medication that you may be taking.
Many have reverted to bitter orange extracts to tackle their weight problem after the ban on ephedra by the US drug administration . what is needed is prudence as most consider bitter orange as a health supplement forgetting its rather potent effect on the body .
July 31, 2009 12:03 PM
Sarsaparilla can be found natively growing in the Pacific regions of Mexico, along the coast to Peru. The root is commonly used to make root beer. The sarsaparilla plant is mostly a find. It can primarily be found in Mexico, Central America and South America. The root of the plant is the most valued portion. It has been used for medicinal purposes for centuries, much like ginseng or licorice root. Sarsaparilla root is very bitter. Because of this, it was a common practice for pharmacists to distill the useful chemicals from this herb and mix them with sugar water. From this, a very popular beverage called sarsaparilla was born. This was years before other chemists would invent other medicinal drinks like the original Pepsi and 7-Up.
The sarsaparilla plant was most definitely used as a medicinal tonic, but it was often served as a sweetened beverage. Some formulas substituted sarsaparilla root with a combination of birch oil and sassafras, which is a treat that is found in the western United States. Some believe that the informal name of the drink, sasparilla, indicates the use of sassafras extract, while others say the name is a corruption of the original sarsaparilla. Unfortunately, the modern beverage is Closer to a birch oil/sassafras mixture than the more bitter sarsaparilla extract. The roots of the sarsaparilla plant can be purchased in certain grocery or health food stores. The beverage called sarsaparilla is a little more difficult to find. Smaller bottling companies may produce a version for local consumption, but that national interest in root beer, sarsaparilla’s cousin, has made it much harder to come by.
Often, sarsaparilla is used in glandular balance formulas. This is because components in sarsaparilla help with the production of testosterone and progesterone. The herb also stimulates the metabolism, aids digestion, and improves the appetite. It has been used to help with gas and edema, along with other related conditions. Additionally, studies have shown that this herb contains diuretic activity and also increased the elimination of chlorides and uric acid. Sarsaparilla is beneficial for many skin ailments. Among these are psoriasis, eczema, and leprosy. This has been found to be true in various studies. The herb also works as an anti-inflammatory by increasing circulation to rheumatic joints. It also helps to relieve arthritis and other inflammatory conditions. This herb also stimulates breathing when congestion occurs. It even helps to purify the blood.
The root of the sarsaparilla plant are used to provide alterative, anti-inflammatory, antiseptic, aromatic, blood purifier, carminative, diaphoretic, diuretic, febrifuge, and stimulant properties. The primary nutrients found in this herb are copper, iodine, iron, manganese, silicon, sodium, vitamins A, B-complex, and C, and zinc. Primarily, sarsaparilla is extremely beneficial in treating joint aches and pains, arthritis, blood impurities, eczema, gas, glandular problems, hormone imbalance, inflammation, psoriasis, skin diseases, and syphilis.
Additionally, the herb is very helpful in dealing with age spots, appetite loss, cods, congestion, edema, sore eyes, fevers, gout, impotence, leprosy, menopausal symptoms, metabolism disorders, skin parasites, chronic rheumatism, ringworms, primary tuberculosis, and sores. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen to prevent prescription drug interaction. For more information on the many beneficial effects provided by sarsaparilla, please feel free to consult a representative from your local health food store with questions.
Sarsaparilla root is available in capsule and tablet forms at your local or internet health food store. It is recommended that you look for name brands like Solaray, Natures Way, and Natures Plus to ensure quality and purity of the product you purchase.
Natural Soap Bars
January 20, 2009 09:34 AM
With the earth-friendly topic being on so many people’s minds lately, consumers are realizing that using natural personal care products is a simple way to start with a greener lifestyle. Consumer demands for natural personal care products has actually experienced double digit growth consistently for the past few years, with this trend not expected to slow. At the same time, non-natural personal care is typically seeing less than a five percent growth.
Natural is currently one of the fastest growing subcategories of personal care, with a large crossover clientele emerging and many mass, grocery, and drug stores are now offering natural products. Success has moved natural ingredients into mainstream brands, opened doors to food, drug, and mass merchant distribution, and driven major consumer brands to enter the market. Larger mass market companies are now realizing the extreme growth potential and profitability of the natural market as compared to the traditional personal care market.
Manufactures have been trying many different things in the soap market including making soaps for sensitive skin, using fair trade ingredients, and discovering new ways to make creamier and more moisturizing soaps. Consumers are looking for their natural personal care products to have the same easy use and performance level of chemical-based personal care products. There is also an increase in interest in using food-based ingredients, as it is appealing on a consumer level due to the familiarity, because if you can eat it, it must be safe.
Fragrance-free and sensitive-sin products are also on the rise, with thirty percent of the population reporting some sensitivity to fragrance, while more than eighty percent report that exposure to fragrances is bothersome, with many synthetic fragrances containing phthalates, which are linked to birth defects and health-related issues. However, the consumer must know that there is actually a difference between unscented and fragrance-free. Unscented products mask the odor of the actual formula with a fragrance, which leaves the potential for skin irritation and allergic reactions.
The Natural Products Association recently launched a Natural Care Product Seal and Standard so that consumers could more easily identify products with truly natural ingredients. Adhering to these requirements can prove difficult for manufactures of natural soaps. Soaps and creams present several challenges to formulators who are seeking to avoid chemicals and synthetic materials. Soaps made according to the above standards will cleanse skin and hair, although they may have an appearance and texture that was different than many consumers are use to. These soaps may be thin, create minimal foam, and may have a shorter shelf life than other natural products that are made according to alternative ingredient standards.
Although bar soaps are staple products year round, liquid soaps are currently gaining popularity, as bar soaps are often drying to the skin and have a high pH. Liquid soaps, on the other hand, have a pH Closer to that of skin and also have the ability to moisturize. The market should see an increase in liquid soaps in the future, as the population ages and skin is drier and needs more moisture, leaving the moisturizing abilities of liquid soaps to meet these needs.
October 15, 2008 09:46 AM
To fight off aging you have to understand what causes it, and the take steps to avoid these causes. It is fairly obvious that all causes of aging cannot be circumvented, but there are things that can be done to keep some of them at bay. Here, we are specifically concerned with the aging of your skin, which is the most visible form of aging. The first aspect of aging to understand is that there are two types: intrinsic and extrinsic.
Intrinsic aging is natural aging, and is largely genetic. Starting when you are fairly young, normally in the early to mid 20s, intrinsic aging is typified by wrinkling, hair loss or graying of the hair, hollowing of cheeks and other areas where the fat underneath the skin that normally contributes to your physical appearance is lost, and also bone loss that causes your skin to sag due a gradual loss of the structure that sculpts your physical appearance.
The age at which this occurs, and its speed is determined by your genes; although the process generally begins around the mid 20s, the speed with which it progresses is genetically controlled.
This is where grape seed extract can help. Extrinsic aging is not genetic, but environmental. Ten majority of this type of aging is due to exposure to the damaging UV light of the sun, which cause the typical 'leathery' look of the skin of people raised in areas such locations as the hotter parts of Australia and the USA, without the benefit of the native skin pigmentation that filters out these harmful ultra-violet rays.
Other factors that can cause the same degradation of your skin cells are smoking, the way you sleep and gravity. The sun generates free radicals (more on these later) that can destroy skin cells, cause freckles, leathery skin and a blotched complexion and also skin cancer. Smokers are more likely to develop leathery and wrinkled skin than non-smokers, and as the elasticity of your skin reduces, gravity cause jowls to develop and also a more pronounced lower lip.
Even your sleeping position can make you appear to age quicker, particularly using the same sleeping position on your pillow each night that cause what are known as sleep lines, that are really wrinkles that are difficult, if not impossible to remove. However, one of the most relevant factors is pollution, and the effects of car emissions, pesticides and other agricultural chemicals, paint fumes and 1001 other forms of chemical pollution that produce free radicals.
Where grape seed extract is involved in fighting off aging is in extrinsic aging is by destroying the free radicals. All substances, from the air to the oceans, are formed of atoms that contain electrons. Stable molecules contain an even number of electrons, or what are known as 'electron pairs'. When a molecule loses one electron it is known as a free radical, whose prime purpose in its very short life is to steal an electron from the nearest molecule. This 'short' lifetime can as long as a day or as short as thousandth of a second: it depends on is size and the degree of steric hindrance to the reaction with the spare electron.
Now that the reasons for aging and the nature of free radicals are better understood it is easier for you understand why grape seed extract can help to fight aging caused by the effects of free radicals on your skin.
Grape seed is a waste product of the wine industry. You cannot make wine from grape seeds, so they are removed from the final product by filtration or sedimentation. It contains a large number of phytonutrients, the most important being polyphenols in the form of flavanoids, lipids and carbohydrates. It also contains proteins that don't have much of an effect on aging. Flavonoids (also spelled flavanoids) are powerful antioxidants that destroy free radicals; they are twenty times as powerful as Vitamin E and over fifty times more powerful an antioxidant than Vitamin C.
Both of these vitamins are regarded as strong antioxidants in their own right, which is an indication of how good grape seed extract is at killing free radicals. It's like a combination of Harry Callahan, Paul Kersey, John McClane and the whole of the Magnificent Seven after the scavengers in your body cells. They succeed, and do it in spades!
Not only do the ingredients of grape seed extract kill off free radicals with the efficiency of a Delta Task Force, but are also anti-allergenic, anti-inflammatory, anti-cancer and anti just about anything else you can think of. However, let's have an even Closer look and find out exactly what polyphenols are present in this so-called wonder juice.
Procyanadin was originally named Vitamin P in 1936 by its discoverer, Prof. Jacques Masquelier, and is believed to bond with collagen to protect you from premature aging by retaining and even improving the elasticity of your skin. An added benefit is that it also improves the elasticity of your blood vessels, and so helps to fight off the effects of high blood pressure and places less strain on your heart. The overall effect on your face is to practically give you a chemical face lift and also provide protection from the damaging effect of the UV component of sunlight through its lethal attitude towards the free radicals that UV radiation generates.
Another component of grape seed extract particularly that of muscadine grapes is resveratrol; a phytoalexin that has strong anti-inflammatory properties and can also fight off the effects of aging. Phytoalexins are antibiotics produced by plants that are under attack, and, in addition to helping you age slower, confers other benefits to your body including helping your brain to carry out its work more efficiently.
All in all, grape seed extract confers many benefits to your health and is also believed to possess powerful anti-cancer properties. However, it is for its ability to fight off aging that most people use it as a supplement, and in this respect it has been found to be extremely effective. Any antioxidant is of benefit to your body, but grape seed extract is of particular benefit due its high antioxidant potency.
Fight Histamine With Quercetin
February 11, 2008 03:48 PM
Quercetin is one of the more powerful of the body’s antioxidants, and it can also be used to reduce the rate of histamine release by the body normally initiated by contact with an allergenic substance (for which your immune system has designed an antigen). We shall examine the biochemical mechanism which this is achieved, but first let’s have a Closer look at quercetin and what it actually is.
Quercetin is what is known as a phytochemical, which is simply the scientific name for a chemical that is naturally produced by plants. Other phytochemicals include vitamin C and omega 3 fatty acids, so the term is very broad ranging for any substance that is produced by plants. It is commonly known as a flavanol, one of a family of compounds known as flavonoids that give color to plants.
It is a very active flavonoid, with very powerful antioxidant properties, in addition to acting as an anti-histamine and anti-inflammatory. Histamine is an amine released as part of the body’s immune response to allergenics, and quercetin inhibits its manufacture and release. This amine is an irritant and can itself cause inflammation and the other symptoms associated with allergies such as runny and itchy eyes, a stuffy nose, sneezing and itchy spots. Quercetin can be used to alleviate these symptoms by blocking the manufacture in the body of the histamine that causes them.
It demonstrates other anti-inflammatory properties such as alleviating the symptoms of arthritis, and also helps to destroy free radicals in the body through its strong antioxidant properties, but before we discuss how it does this we shall have a Closer look at the mechanisms used in its effect in inhibiting histamine.
Calmodulin is a protein that is used to transport calcium ions, Ca++, across the membranes of certain cells in the body, and by doing so it helps to mediate a number of biochemical processes within the body, among them the immune response and inflammation. It should not be thought these are always unwelcome responses: on the contrary, they are the body’s way of reacting to foreign bodies and preventing more serious conditions from developing.
However, there are instances where the body can become sensitized to certain substances and overreact to their presence leading to conditions such as hay fever or, considerably more serious, asthma. These are just two of the undesirable manifestations of the human immune system that we would be better without. What quercetin does is to prevent calmodulin from properly binding to certain enzymic proteins and so suppress the effect of these proteins. Among these are the enzymes that control the secretion of histamine from mast cells.
Mast cells are found mainly in areas prone to injury and at the interface between internal tissues and outside world, such as the nose, mouth, lungs, eyes, blood vessels and feet. They contain granules rich in histamine that degranulate and released the histamine when the immune system detects foreign bodies such as pollen grains and dust mites, especially when the body has created antigens against them.
Quercetin suppresses the release of histamine from the granules in the mast cells by preventing the degranulation. The release of the histamine is not completely halted, but its effects are reduced and quercetin is used in the treatment of asthma where it is believed to help reduce the symptoms by reducing histamine-induced swelling in the airways.
A similar application of this flavonoid is in reducing the inflammatory response to arthritis, the main cause of the swelling of this painful condition. Your skin can also be affected by inflammation that is partially controllable by quercetin. Collagen and fibronectin biosynthesis is increased that help to maintain not only healthy joints, but also to speed up the healing of wounds and repair damaged nerves. It is also believed that quercetin can hold back the effects of aging on the skin, and slow down the formation of wrinkles.
There are other applications of this versatile flavanol, including its effect on acute prostatitis where it reduces oxidative stress and the accompanying inflammation of the prostate gland. In fact, it is believed to have positive effect on many conditions caused by free radical oxidation and excessive reaction by the immune system causing inflammation. Apart from the allergies and arthritis previously referred to, quercetin is believed to have been effectively used in the treatment of gout, macular degeneration and heart disease, and it can also help to prevent the oxidation of low density lipoproteins (LDL) responsible for transporting cholesterol to where it is needed to repair major blood vessels.
When these lipoproteins become oxidized by free radicals then the cholesterol associated with them tends to be excessively deposited in the arteries it is meant to be repairing, and lead to atherosclerosis. This condition can lead to heart failure or to strokes if the blood vessels are in the brain.
Studies have indicated that the flavonoid might help to prevent certain cancers by preventing the nutrition of some types of cancerous cells, effectively killing them. Due to its phytoestrogen properties, quercetin can be used to bind to the sites in cancerous cells that are receptive to estrogen and so prevent their growth. Many types of cancerous cells need estrogen for their growth and proliferation, and phytoestrogens mimic the effect of this hormone. However, these are laboratory studies, and more work is required.
More certain is the effect of quercetin on heart disease due largely to the aforementioned control of cholesterol deposition in your arteries, but also through its ability to strengthen the capillaries. However, when all things are considered, it is in the properties of this non-allergenic bioflavonoid to fight histamine release that it finds it’s most popular and effective use.
So what is the best way to take quercetin? Like most bioflavonoids, it is available naturally in the majority of plant foods. Particularly rich sources are broccoli, red onions, red apple skins, black tea, red wine, red and purple berries and almost all dark green leafy vegetables.
However, the name of the game these days is to take measured doses, and while you should continue to eat these foods, you can also receive controlled doses by use of supplements. From 200 to 500 milligrams thrice daily is a good average dose, depending on the severity of your immune reaction or allergy. Bromelain is believed to improve its absorption in the gut, and quercetin is frequently provided with bromelain, which itself is also a good treatment for allergies and excessive response of your immune system to irritation.
Bromelain is an enzyme, generally extracted from pineapple, and treatments higher than the above doses of quercetin with or without bromelain are available online, although like any natural remedy you should inform your own physician of the dosage you are taking.
There is no better non-allergenic bioflavonoid to fight histamine and its potentially unpleasant effects on your body than quercetin.
Is Wild Yam Natures Progesterone?
November 15, 2007 07:20 AM
Dioscorea villosa, commonly known as wild yam, is a tuberous vine native to North America and parts of Central America. It was used by the Mayan and Aztec civilizations for pain relief and birth control and has also been given the names colic root and rheumatism root, demonstrating this early use of the plant. However, whether it is nature’s progesterone or not is another question that requires close analysis.
These Central American civilizations, of course, did not understand the reason why they were effective. Some of the symptoms treated can be caused by the menopause, and the wild yam is believed to contain natural forms of progesterone that can alleviate some of the adverse effects of the menopause on the body. Like most plants, they also likely act as anti-inflammatories, so relieving the pain of rheumatoid arthritis and other inflammatory conditions.
Like any natural remedy, wild yam had its adherents and its detractors, though in recent years the plant has been used as the raw material for the production of cortisone and a form of progesterone: or at least so it is claimed, so let’s have a Closer look at these claims and determine whether or not wild yam is indeed nature’s progesterone.
The human body uses organic compounds called hormones to regulate many of the chemical activities of the body. The hormones catalyze the chemical reactions and changes needed for the proper functioning of our bodies. Hormones are produced in small chemical factories dotted throughout our body called glands. Each gland is devoted to producing a specific hormone, or a range of them, and each hormone is designed for a specific purpose.
Each has an associated hormone ‘receptor’ at their targeted destination that fits the hormone like a jigsaw piece. When it turns up, the hormone attaches to the receptor and the reaction proceeds. That might be the initiation of energy production in cells, the activation of certain genes or even the stimulation of hair growth by the follicles or of the libido and the natural desire to procreate.
Hormones are manufactured from only three constituents: proteins, amino acids and cholesterol, and the steroidal sex hormones are created from cholesterol. Therefore, don’t reduce your cholesterol level too much!
Prior to puberty, all of the sex hormones are manufactured by the adrenal glands, and after puberty by the ovaries in women and the testes in men. Progesterone is produced initially, and is then used as the building block for all the other sex hormones (hence the prefix ‘pro’). In women these are the estrogens and in males the androgens. Progesterone is made from the start of the menstrual cycle, and after day 12 they have reached a high enough level to halt ovulation. Progesterone levels continue to rise for about 8 days, and then if fertilization has not occurred, the progesterone levels trigger menstruation, and the lining of the womb is detached and expelled.
During certain phases of the menstrual cycle, the levels of the hormones estrogen and progesterone drop off, although the exact reason for the many and varied symptoms of pre-menstrual syndrome (PMS) are still unknown to a large extend. There appear to be several contributing factors, though estrogen and progesterone certainly appear to be two of the major ones. We shall concentrate here on the progesterone factor because that is what wild yam is claimed to address.
Although the main function of progesterone is to generate estrogen and testosterone, to restore the libido after menstruation, and maintain the integrity of the lining of the uterus and aid in gestation, it has many other purposes such as in thermogenesis (burning of body fats), protection against osteoporosis and is also believed to have a natural anti-depressant action. These are all supported by the symptoms that appear when the body is low in progesterone levels: depression, sudden increase in body fat, mood swings, loss of sex drive and a susceptibility to weak bones if the deficiency is long-term.
In other words, women that usually suffer from PMS, also generally suffer low progesterone levels. It is believed in some quarters that a progesterone deficiency causes an excess of estrogen that leads to these symptoms in addition to heart disease. No one really knows for sure, but a deficiency of progesterone seems to be the determining factor.
Women with menstrual problems continue to be issued with prescribed synthetic progesterone even though they do not have the same effect as natural progesterone. They can also lead to some unpleasant side effects such as fluid retention, strokes, jaundice, blood clots and depression: some of the symptoms it is intended to alleviate. Some take borage or evening primrose oil for the GLA that helps some of the effects, but this is taken to counter the over-production of the hormone prolactin in some women prior to menstruation, not a deficiency of progesterone.
Wild yam does not cause these symptoms, and is claimed by many to be very effective in alleviating the symptoms of PMS. The problem with the artificial forms of progesterone is that the liver’s job is to destroy foreign hormones, and send them to the digestive tract for expulsion. Natural hormones are not affected in this way, even if they come from a non-human source.
The chemical diosgenin in wild yam is very similar in structure to progesterone, and is believed to be the active principle. It is claimed that it can be used to produce not only progesterone but also other related hormones. However, some medical authorities and practitioners dispute this claim, and there is still a question as to how wild yam works. Because it does work, many people swear by it and claim that they could not live without it.
This is especially true of those that suffer from the more severe effects of PMS, and since wild yam does not work for everybody, it could be connected with the severity of the condition and the symptoms. Whichever is true, there appears to be little doubt in the eyes of those that use it as a cream that wild yam is indeed nature’s progesterone.
Stevia: Sweeten Your Life With Out The Weight Gain
November 13, 2007 02:55 PM
It is possible to sweeten your life with stevia, and without any weight gain, since it as exceptionally sweet herb. In fact it is member of the sunflower family, and is native to parts of South and Central America where it has been used as a sweetener since time immemorial. Also known as sugarleaf, it is a commercial crop, and is available as a dietary supplement.
Extracts of stevia have been found to be up to 300 times as sweet as cane sugar, although does not metabolize in the body to glucose. In fact it is thought to enhance the glucose tolerance of some diabetics, and can be used by people suffering from that condition as a natural sweetener, thus dispensing with the need for artificial sweeteners.
It is also useful for those on diets, especially carbohydrate controlled diets, and any other sweet-toothed person wanting to lose weight and still enjoy their favorite drink or desert. Many recipes have been published using stevia for the preparation of delicious sweets. So why is stevia so sweet and what other uses does it have?
Basically the sweet taste comes from glycosides, which are molecules in which a sugar is bonded to another molecule. The two main glycosides in stevia are called stevioside and rebaudioside. These are formed through glucose combined with the diterpene steviol in different ways, though some minor glycosides also contain rhamnose. Although they contain glucose, the glucose is not released into the bloodstream during digestion and the subsequent biochemistry.
Japan began the cultivation of the plant in the 1970s rather than produce artificial sweeteners that were suspected carcinogens (saccharin and cyclamate). Japan is now the world’s biggest consumer of stevia, even being used in the Japanese Coca Cola plants. Around 40% of Japan’s total sweetener volume is stevia. However, apart from its use as a natural alternative sweetener to sugar, stevia has specific properties, already alluded to, that renders it of particular attraction to certain groups of people, and we shall now take a Closer look at these.
Insulin is a hormone produced by the pancreas that is essential to regulate the glucose content of the blood. It stimulates the cells of the body to take in blood glucose and convert it to glycogen that can be used for energy. Without insulin the blood sugars would increase in concentration without regulation leading to very serious health issues that would eventually result in death.
Diabetes is a condition in which the body either does not produce sufficient insulin, does not use the insulin it produces properly, or produces no insulin at all. Hence, a sweetener that did not exacerbate this situation by being eventually metabolized to glucose, as most sugars are in the body, would be of great benefit to diabetics. This is exactly what stevia is. It is a very powerful sweetener, 250 – 300 times sweeter to the taste-buds than sucrose, normal table sugar, and it does not metabolize to glucose. It is heaven-sent sweetener for diabetics that have a sweet tooth.
It is very safe for them and has been consumed for centuries without any side effects. In fact, studies have indicated that stevia might even regulate the pancreas and help to stabilize the levels of blood glucose in the body, rendering it an effective and safe supplement for those suffering from hypoglycemia (excess blood sugar), diabetes and candidiasis, a yeast infection that thrives on sugar.
Apart from that, stevia is also popular with those who are on a calorie controlled diet – or any other diet for that matter, since an excessive sugar intake invariably leads eventually to weight increase. The 21st century western diet is drowning in sugar, with up to 10 spoonfuls of sugar in every small bottle of cola. There is sugar in cookies, hot dogs, bread, soy sauce, ketchup, cans of beans and peas, and even sugar in cigarettes, though that is the least of the health worries there!
For the first time in history, there are now more overweight and obese people in the world than hungry people, yet the sugar corporations claim that there is no scientific proof that sugar leads to weight increase. Worldwide, diabetes kills 6 people every minute, and obesity caused by the consumption of too much sugar leads to Type II diabetes. It had been shown that fructose is a major player in that corn syrup (fructose) is contained in many soft drinks and foods.
One of the major problems with refined sugars is that they contain nothing but pure carbohydrate. All the vitamins, minerals and other nutrients have been removed, so that when they are consumed, your body has to provide these nutrients needed to metabolize the sugar to glucose and then to energy. Humans cannot live on sugar alone, and in fact you are better drinking water than corn syrup or cane sugar solutions since at least water does not make demands on your existing nutrient store.
It was noted in 1929 by Sir Frederick Banting, one of those scientists credited with the discovery of insulin, that there was a significantly large proportion of diabetes among the sugar plantation owners that ate large quantities of refined sugar, whereas there was none detected in the cane harvesters who were able to chew on only the raw cane. The raw cane contains the minerals and vitamins needed to metabolize the sucrose.
Stevia is a potential answer to this problem, and it is such an obvious one that there are a lot of politics regarding its use. The big USA sugar corporations will undoubtedly be opposed to it, and the FDA has refused to allow its use as a food additive, only as a dietary supplement, yet its use in Japan has been very successful. It is also used throughout East Asia, including China, Korea and Taiwan, and also in South America, Israel and some areas of the Caribbean. It is available as a green powder in its crude form, and also brownish syrup redolent of licorice, but also as a more refined white powder that is likely best used as weak solution due to its sweetness.
It is totally free of calories; this may come as a surprise to many since it tastes so sweet. It is an excellent sweetener for children’s drinks since it does not cause cavities: unlike sugar it is not degraded by bacteria to produce the corrosive acid that eats into the enamel. It does not metabolize to a burst of energy that is practically addictive, since that generally then leads to tiredness and the need for more sugar to make up for it.
Stevia does not cause diabetes in any form, is not a food for yeast and it is beneficial to the pancreas. In short, it is a completely safe food supplement that has been used for centuries without ill effect, and if you want to prevent yourself from adding weight and protect against the possibility of Type II diabetes in particular, then stevia should be your sweetener of choice.
Staying Healthy Means Keeping Your Blood In The Proper PH
October 21, 2007 07:04 PM
The blood should be electrolytically neutral, or very slightly alkaline. The proper pH for blood should be 7 or just above it, and many claim that it should be 7.35. In fact the truth is that your blood pH should be between 7.2 and 7.6. Outside these limits and you could have serious health problems, with your brain particularly being affected.
For those who have forgotten their school chemistry, pH is a measurement of the level of acidity or alkalinity of an aqueous solution. Anything over 7 is said to be alkaline, and below 7 is acidic. Where the pH has to be maintained at a certain level, a material called a buffer is used that counteracts the effects of other acids and alkalis to maintain the desired pH range. Buffers are very common in nature, as would be expected of life forms that depend upon water and aqueous solutions for their survival. Blood is an aqueous solution containing plasma, blood cells, nutrients and various other ingredients in both solution and dispersed solid form.
The human body possesses a very effective pH maintenance system that depends on various buffers, the kidneys and the lungs. Lets have a Closer look at buffers and how they work. pH is, in fact, a measurement of the concentration of hydrogen ions (H+) in a solution. The way a buffer works is to absorb or release H+ ions to keep the hydrogen ion concentration at a specific level. If there are too many H+ ions present in the blood, and it becomes too acidic, then the buffer will mop up the excess. If there are too few, and the blood becomes too alkaline, then the buffer will release more hydrogen ions into the blood. In this way the pH is maintained at the limits mentioned above.
Buffers in the human body include some forms of protein, phosphates and also hemoglobin. However, if the pH variations are more than just occasional, the buffers have a limited capability, and a more permanent solution is needed. If the blood is continually becoming too acidic, the bicarbonate ion is used to clear them up. Just as bicarbonate of soda is used to clear up excess acidity in your stomach that causes indigestion, so it can be used to clear up excess acidity in the blood. But how do we get the bicarbonate into the blood?
When the lungs inhale oxygen, they then exhale carbon dioxide. The bicarbonate ion, also called the hydrogen carbonate ion, is formed in the blood by dissolved carbon dioxide. The faster we breathe the more carbon dioxide we exhale and the less is left in the blood to form bicarbonate. The slower we breathe, the more carbon dioxide is available in the blood for bicarbonate. Thus, when our blood acidity increases we breathe slower, and when it decreases we breathe faster since less carbon dioxide is needed in the blood to form bicarbonate to neutralize the acid.
The kidneys also help to regulate the pH of the blood, although the biochemistry involved is fairly complex, and will not be covered here. It is enough to state that the body has a number of routes by which it can control the pH of the blood.
Current thinking is that alkaline and acidic foods should be balanced in your diet in order to place less of a strain on the body’s pH control systems. Since the blood pH must be slightly alkaline, then it might make sense to eat a slightly alkaline diet. However, it is not the actual food that matters, but what happens when the food is digested. Hence, orange juice is classed as an alkaline food even though it is high in citric acid and itself has a low pH. The same is true of lemons. They taste very sour, yet the result after digestion is alkaline. It is the end result that counts. After all, the stomach acid is very strong and very highly acidic, and eating slightly alkaline foods is not going to alter that. The digestive juices have to be highly acidic to break down the organic matter.
It had been calculated that a mix of around d 75% alkaline and 25% acidic food is a good combination of the two types to provide approximately the desired blood pH. Among the common acidic foods are meat, fish, poultry, plums, grains, eggs, wine, cheese and offal. The alkaline foods are most fruits and vegetables, orange and lemon juice, melons, potatoes and chocolate. Hence, it is possible to eat beef and chicken, and have the odd glass of wine so long as we eat plenty of fresh fruit and vegetables. There is nothing at all unusual with that diet, and it underlines the importance of eating a healthy balanced diet. While more greens and whole foods are definitely healthier for you, you should not eat exclusively an alkaline diet.
If your blood pH is on the high side of the limit, then you can eat a bit more meat or fish, and if on the low side eat a more vegetarian style diet. It is important, however, that you eat healthily, irrespective of whether you are eating alkaline or acidic foods. Through history, the human race has adopted a more acidic diet than the ancient hunter gatherers. Grains are a relatively recent invention, introduced after the invention of stone tools to mill them, and dairy products are also relatively recent in terms of the whole of human history. Even the consumption of meat only began after mankind learned first how to trap and then developed tools to enable them to kill their prey.
Human biochemistry, then, has developed from a predominantly vegetarian diet. However, protein is still very important, and while protein intake is necessary, should comprise no more than 20% - 25% of your total food intake. The rest should comprise of mainly fruits and vegetables, with whole rather than refined or processes foods predominating. Sugar was not eaten in quantity until the industrial revolution.
Measuring the pH of your blood is easy to do. It is simply a matter of using pH paper strips and checking the color change with your blood. They are available at most pharmacies and health food stores. If your pH level varies from 7.4 or 7.5, then you should change your diet accordingly. Higher than this, then eat more acidic foods, and if lower you should eat more alkaline food. It is simple equation, and the changes you will have to make to your diet will be minimal. Some of these changes can be made by the use of supplements that are carefully balanced to maintain your blood in the proper pH.
The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
May 18, 2007 01:06 PM
The Awesome Foursome: Coenzyme Q10, L-Carnitine,
The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a Closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.
Energy Recycling through the Electron Transport Chain
Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.
Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.
In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.
What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.
Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.
Transporting the Cellular Energy Fuel
Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.
Rebuilding the Cellular Energy Pool
As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.
When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.
Ribose is the only compound used by the body to refill this energy pool. Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency. Ribose is made naturally in the cells from glucose. In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis. So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.
Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy. Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days. But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose. Conditions like ischemic heart disease or congestive heart failure fall into this category. In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.
Switching on the Energy Enzymes
Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism. Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work. Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.
Magnesium deficiency reduces the activity of important enzymes used in energy metabolism. Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function. Small changes in magnesium levels can have a substantial effect on heart and blood vessel function. While magnesium is found in most foods - particularly vegetables - deficiencies are increasing. Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.
Supporting the Links in The Energy Cycle Chain – the Synergy
Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.
The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.
The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.
Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.
These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.
The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.
L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.
Fight for supplements now—it’s a matter of life and death.
May 20, 2006 01:15 PM
More than 100,000 people a year die from obesity. More than 100,000 people a year die from synthetic drugs’ side effects. These staggering numbers are a direct result of food and drugs. Isn’t there a governmental agency that monitors our food and drugs? Oh yes—it’s called the Food and Drug Administration (FDA). Judging by the numbers, the FDA needs to immediately start improving the quality of our food supply and imposing stricter safety regulations on the pharmaceutical industry. It’s a matter of life and death.
The mortality numbers associated with obesity and drugs are conservative, the tip of a massive iceberg. All signs indicate that the US, like the Titanic, is on a course for a disastrous collision with an unhealthy food supply and increasingly ubiquitous drugs. At the helm is the FDA, navigating like a dangerously distracted captain. The iceberg looms but instead of steering away, captain FDA scrutinizes a harmless ice cube in his glass—the nutritional supplement industry.
As the Iceberg draws Closer, the captain is joined by his crew: Senators Dick Durbin, Tom Harkin and Orrin Hatch. Oblivious to the threat they gather around the captain’s ice cube: “this ice cube could be dangerous. How can we minimize the treat? Ice cubes should probably be controlled by the FDA. Let’s draft legislation that treats this ice cube like a iceberg, just in case.” Meanwhile, we are about to crash full speed into the real danger.
Headed for Disaster
This analogy reflects reality: Durbin, Harkin, and Hatch are drafting non-causal Adverse Event Reporting (AER) legislation that could destroy our health freedom. Under AER, supplements will be associated with adverse events like heart attacks and strokes—even if they had nothing to do with, and did not cause, those events. Treating safe, natural supplements as if they are drugs makes about as much sense as treating an ice cube like an iceberg.
While these senators target natural supplements, American citizens continue to die at alarming rates because of deadly pharmaceutical drugs and an unhealthy food supply. Where are the priorities of these misguided senators and the FDA? Dietary supplements are part of the solution to this problem, helping to support health and ensure proper nutrition.
AER is a health emergency! Durbin’s legislation could be introduced any day now. We the people, the passengers on this poorly navigated ship , must mutiny, storm the helm, fight against non-causal AER and steer towards health freedom.
We must Take Control!
If we want safe, beneficial nutritional supplements, we must exercise democratic power of the people. AER is poised to implementation. We must rise up together and tell our elected officials that we demand the right to take vitamins! Send Fax today, and send another fax tomorrow to make your voice heard! Fax vitamin adversary Senator Dick Durbin at 202-228-0400, and let him know you will never vote for an enemy of health freedom. Fax key vitamin players in Congress, Senators Tom Harkin at 202-224-9369 and Orrin at 202-224-6331. Let these senators know that their support of non-causal AER will forever tarnish their legacies. Fax Senator Michael Enzi, Chairman of the senate Subcommittee on health, Education, Labor and Pensions, at 202-228-0359. Tell Senator Enzi in no uncertain terms that dietary supplements help keep you and your family healthy, and it is your right to take them.
Visit //www.NHA2006.com/ and use revolutionary technology to enable visitors to rapidly and easily compose letters and faxes to Congress. For health, freedom and liberty, join the NHA.
Night Health: A new approach to improving sleep.
May 12, 2006 05:41 PM
Our night health, including the quality of our sleep and dreams, may be the most critical overlooked factor contributing to both emotional and physical illness in modern times. For millions, night is a time of growing frustration and deepening struggle with insomnia as well as compromised and insufficient sleep. Mounting data has confirmed that sleep problems are strongly associated with virtually all major illnesses ranging from cardiovascular disease to diabetes, infections and cancer, and obesity to depression.
Night health refers to a new approach to sleep and dreams that integrates complementary and alternative medicine with effective conventional perspectives. It is essentially a comprehensive body-mind approach to sleep. The first in a series of articles introducing the concept of night health, this article begins with a Closer look at the limitations of the simulated sleep offered by sleeping pills. It then examines the basic alternative of supplemented sleep: the place of natural sleep-supporting supplements. Finally, it offers suggestions for increasing the utilization of such alternatives by supplementing supplements with essential information, education and guidance offered by a new and unique software program and the first book about integrative sleep health.
As the public becomes increasingly aware of the health ramifications of sleep disturbances, more and more people are turning to sleeping pills. In fact, according to the IMS Health research, about 42 million prescriptions for sleeping pills were filled last year in the U.S. This represents a nearly 60 percent increase over the past five years alone. Some projections anticipate that the current $2.7 billion in annual sleeping pill sales will more than triple by 2010.
But instead of solving the problem, sleeping pills often make sleep problems worse. Sleeping pills commonly result in dependence. They can alter normal sleep architecture, cause amnesia and residual daytime “hangovers,” and they often result in rebound insomnias when discontinued. Some sleep specialists argue that sleeping pill use is further associated with significant increases in mortality. Given the sense of desperation that can accompany insomnia, even such very serious concerns have not prevented sales of sleeping pills from skyrocketing in recent years.
We are currently witnessing an unprecedented advertising campaign on the part of the pharmaceutical industry designed to convince the public that sleep medications are indeed a safe and effective strategy for addressing sleep problems. Despite clever and seductive advertising, however, it remains highly questionable whether sleeping pills can truly offer us sleep. I believe it is more accurate to say that they result in a kind of artificial or simulated sleep. Compared to natural slumber, sleeping pills cause a chemical knockout. Unfortunately, so many people have slept poorly for so long, they have forgotten what it is like to experience truly restorative, deep and refreshing natural slumber. Instead, many people now hold a naïve, limited sense of healthful sleep, confusing it with being knocked out. And sleeping pills satisfy that very naïve notion of sleep.
Rather than artificially simulating sleep with chemical knockouts, sleep-promoting supplements such as melatonin, valerian, and other botanicals support that body’s own sleep-facilitating mechanisms more naturally. Such products work in greater harmony with nature and, unlike conventional drugs, they do not stimulate sleep, they supplement sleep. I think of natural supplements inviting us to sleep. The very potency of many natural products lies in their very gentleness, which works cooperatively with both body and mind to induce healthful sleep.
I believe that the potential benefits and markets for such supplements remain largely untapped. Consumers’ expectations that sleep aids should knock them out rather than gently assist them in letting go into sleep must be addressed through targeted education and information campaigns. Consumers also need to learn how to use alternative sleep supplements in the context of a healthy sleep lifestyle or positive night health.
As helpful as they can be in promoting night health, sleep supplements alone will not do the trick. In fact, I believe many people get discouraged and discount the potentially positive benefits of sleep supplements after using them without proper guidance and understanding. Sleep supplements work best when they are geared to work synergistically as a part of a larger night health promotion program.
The availability of a wide range of over-the-counter health supplements offers an important freedom in healthcare choices. But with increased freedom comes increased responsibility. Consumers need to become significantly more informed. Particularly with regard to night health, such supplements need to be personalized and prescriptive. When it comes to sleep health, one size does not fit all. Whether we choose melatonin or valerian or a specific blend depends upon who we are and exactly what we need. By prescriptive I do not mean ordered by a physician, but specifically tailored to the needs of the individual.
Because of a significant shortage of health care professionals knowledgeable about sleep and the alarming trend towards increased use of sleeping pills, I have assisted in the development of a unique software program that provides sleep solutions that are both personalized and prescriptive. After more than a decade in development, the sleep advisor—an expert software system that thoroughly evaluates and provides personalized comprehensive recommendations for improving sleep—is now available.
More recently, I completed the first truly integrative book on night health. Healing night: the science and spirit of sleeping, dreaming, and awakening offers a new, comprehensive perspective on night health that complements the sleep advisors high pragmatic approach. Together, healing night and the sleep advisor offers essential supplements to sleep supplements.
Rubin R Naiman is a psychologist and clinical assistant professor of medicine at the university of Arizona’s health sciences center. He is also the sleep and dream specialist for dr. Andrew weil;s world renowned program in integrative medicine. Currently he serves as the sleep specialist at Miraval Resort, and is in private practice in Tuscon, AZ.
The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Rubin R. Naiman, PhD
Best Sugar Balance Svetol (green coffee extract)
May 05, 2006 06:30 PM
Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids.
In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.*
Maintains healthy blood sugar levels when used as a part of the diet*
Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1
Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (Closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3
Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.
Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.
Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT).
More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year.
The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5
It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism.
A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6
RESEARCH ON SVETOL®
Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results.
In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7
Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption.
The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.*
Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7
*This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4.
2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402.
3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7.
4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10.
5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15.
6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.
7) Berkem.Text on Svetol®.Gardonne, France: November 2005.
California Proposition 65 (Prop 65) and Progesterone Cream Warnings
February 17, 2006 06:29 PM
Scientific Safety Information on Progesterone
California Proposition 65 (Prop 65) and Progesterone Cream Warnings Amy Kosowski, M.S., LDN
Prop 65: What is it?
Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986 , was enacted as a ballot initiative in the state of California in November of 1986. The Proposition was intended by its authors to protect California citizens and the State's drinking water sources from chemicals known to cause cancer, birth defects or other reproductive harm, and to inform citizens about exposures to such chemicals 1.
Proposition 65 requires the Governor to publish, at least annually, a list of chemicals “known to the state to cause cancer or reproductive toxicity .” Progesterone, as well as other human hormones, appear on this list 1. Set forth below is the information that formed the bases for the addition of progesterone to the Prop 65 list by the California Office of Environmental Health Hazard Assessment (“OEHHA”).
Prop 65 and Progesterone - Perspective
In August of 2004, OEHHA published a document stating the rationale for the addition of Progesterone to the Prop 65 list 2. This document is a review of human, animal, and in vitro studies that used progesterone, synthetic progestins, and other progestagens (progesterone-like compounds). Experimental data from the use of all of these compounds were mixed together, along with data from studies using other steroid hormone derivatives (mainly synthetic estrogens) and many different methods of administration.
Although this review covered the existing scientific literature on progesterone and its many derivative compounds, there are many problems with the type of data analysis that was employed.
First, progesterone is endogenous to humans and necessary for bone and reproductive health while progestins and other synthetic progestagens are not. Progestins and progestagens are similar in molecular structure to progesterone, but when they bind to progesterone receptors, their effects are usually much stronger and more likely to cause abnormal physiologic responses 3, 4. Furthermore, the majority of the studies concerning the health effects of these progesterone derivatives involved combinations with synthetic estrogens 2-4.
There were very few studies mentioned in the 2004 document that used exclusively bio-identical progesterone (the kind found normally produced by humans as well as that used in progesterone creams), and those studies that did were at supra-physiologic doses (very high). The doses of progesterone ranged from 10-1000 times the dose usually recommended by manufacturers of progesterone creams 2, although in a few cases, the doses were Closer to the recommended dosages.
The route of administration of progesterone is also at issue. All of the studies cited in the OEHHA document used either oral, injected, or suppository forms of hormones; none was conducted using transdermal creams. This is an important consideration because hormones absorbed through the skin are metabolized differently than hormones that are administered via other routes 5, 6.
Putting it Together
While the OEHHA Prop 65 reference document on progesterone 2 is a broad survey of the published scientific literature examining the potential effects of the pharmaceutical use of progesterone and its synthetic derivatives, it is not clear at all that these effects would be seen with the use of low-dose progesterone creams.
The OEHHA Prop 65 progesterone document evaluates a broad range of information regarding progesterone and synthetic materials that are not natural progesterone. The conclusion reached was not challenged, and it is on that basis that progesterone creams now carry the Prop 65 warning.
1 California OEHHA Web Site: //www.oehha.ca.gov/prop65/p65faq.html .
2 Reproductive and Cancer Hazard Assessment Section, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency (2004) Evidence on the developmental and Reproductive Toxicity of Progesterone.
3 Campagnoli C, Abba C, Ambroggio S, Peris C (2005) Pregnancy, progesterone and progestin in relation to breast cancer risk. J Steroid Biochem Mol Biol 97(5):441-450.
4 Campagnoli C , Clavel-Chapelon F , Kaaks R , Peris C , Berrino F (2005) Progestins and progesterone in hormone replacement therapy and the risk of breast cancer. Steroid Biochem Mol Biol 2005 96(2):95-108.
5 de Lignieres B, Dennerstein L, Backstrom T (1995) Influence of route of administration on progesterone metabolism. Maturitas 21:251-257.
6 Gompel A, et al. (2000) Progestins were also proapoptotic in normal as well as in hormone-dependent breast cancer cells. Steroids 65(10-11):593-598.
7 Bu SZ ( 1997) Progesterone induces apoptosis and up-regulation of p53 expression in human ovarian carcinoma cell lines. Cancer 79(10):1944-50.
Pomeratrol™ Fact Sheet
December 19, 2005 09:09 AM
Pomeratrol™ Fact SheetNeil E. Levin, CCN, DANLA 9/28/04
USER: Those needing antioxidant protection; People with a family history of cell growth abnormalities; Anyone concerned with aging
KEY INGREDIENT(S): Pomegranate fruit standardized extract 200 mg. (Punica granatum) containing 80% total polyphenols, including 40% Ellagic acid, Resveratrol (100% trans-resveratrol) 20 mg. from a blend of Japanese knotweed root extract (Polygonum cuspidatum) and grape skin extract (Vitis vinifera)
POTENTIAL BENEFITS: Ellagic acid is a polyphenol compound found in raspberries, strawberries, pomegranates, and other fruit. It has been shown to normalize cell death of abnormal cells, a process called apoptosis. This enhances the body’s cell growth control system by providing an important plant substance. It may bind to DNA to prevent damage to this all-important genetic material. This is a key step in preventing cell damage that leads to signs of aging.
The American Cancer Society says that research in animal and laboratory models has found that ellagic acid inhibits the abnormal growth of certain cells. Research at Ohio State University indicates that berries typically contain a few milligrams per ounce of ellagic acid, the actual level varying quite a bit from variables such as species, variety and growing conditions.
Resveratrol is an antioxidant compound that is a phytoestrogen, or plant estrogen, which is protective of hormone-mediated cells in the body. Resveratrol is a potent antioxidant if stabilized. If not stable, it may quickly metabolize out of the body. This compound is believed responsible for some of the beneficial effects of moderate red wine drinking on the cardiovascular system. Resveratrol is also considered to be beneficial to smokers’ lung tissue if it is stabilized to last long enough in the system to be transported there. Resveratrol is also an inhibitor of the COX-2 inflammatory enzyme and encourages cell death (apoptosis) of abnormally growing cells. In insect experiments resveratrol even repaired DNA, leading to a longer life for healthy cells even as it helped get rid of unhealthy cells. Again, this ability to protect cells and help the body rid itself of abnormal cells is a key factor in preventing signs of aging. One liter of red wine contains between 1.5 and 3 mg. of resveratrol.
OTHER IMPORTANT ISSUES: Resveratrol is a difficult substance to stabilize. Because of the difference between resveratrol produced in the oxygen-poor environment in red wine and the form of resveratrol in unstabilized supplements, it has long been thought that resveratrol supplements were not very effective in comparison with wine. Knowing the importance of how a resveratrol supplement is metabolized, Now’s scientific staff has recently developed a special technique of stabilizing this compound in order to have an antioxidant effect Closer to drinking a good glass of wine. While both trans and cis forms of resveratrol are naturally occurring, most of the recorded health benefits are attributed to the trans form. Now’s Pomeratrol provides trans-resveratrol.
DOSE: One capsule per day. Resveratrol has been used safely in studies at doses equivalent to 500 mg./day.
COMPLEMENTARY PRODUCTS: Other antioxidants and plant compounds: Vitamin C, pycnogenol, grape seed extract, and alpha lipoic acid.
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. There are some indications that resveratrol is a mild anticoagulant ("blood thinner"), and it also may help keep blood vessels to remain open and flexible. Caution should be used by those on blood-thinning drugs. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
December 17, 2005 10:40 AM
Date Sugar - Of the many alternatives to table sugar, the pleasant tasting extract of dehydrated dates may be one of the most natural and nutrient dense. While it can be used for a plethora of applications, the most common are in cereals, oatmeal, baked goods, beverages and puddings. In fact, date sugar bares a Closer resemblance to food than it does to a sweetener. Nutritionally, it’s loaded with vitamins and minerals, especially potassium, magnesium, calcium, iron and phosphorus. Perhaps the most fascinating aspect of this natural sweetener is that it contain significant amounts of fiber. Best of all, date sugar is the closest in sweetness to the table sugar many have grown accustomed to.
Organic Life Vitamins
October 13, 2005 11:09 AM
Peter Gillham has formulated a key nutritional step toward obtaining outstanding health and vitality—Organic Life Vitamins. This is a complete liquid multi-vitamin and mineral with some exciting pluses you won’t find elsewhere .
Liquids absorb better. Organic Life Vitamins has been designed for maximum absorption, thereby allowing your body to assimilate vital life-giving nutrients in just minutes!
Another benefit of this liquid formulation—with its delicious berry taste—is that you don’t have to purchase and take numerous pills and capsules in ord e r to give your body what it needs. And, unlike pills, Organic Life Vitamins contains no binders and fillers.
PUTTING AN END TO CONFUSION
Nutritional supplements range from A to Zinc with a lot of specialized products addressing specific conditions in between.
Our belief is that good health doesn’t have to be complicated or something for which you need five graduate degrees in various disciplines in order to understand.
Organic Life Vitamins is a power-packed premium formulation that supplies the body with the essential nutrients it requires—missing as a result of deficient diets and the stresses of today’s busy lifestyles. It’s that simple.
WHAT’S IN ORGANIC LIFE VITAMINS?
Organic Life Vitamins is a complete multi-vitamin— but it is more than that. Along with 16 key vitamins, Organic Life Vitamins supplies a full range of amino acids, vital minerals and 72 trace minerals (which work in combination with Natural Calm or our Cal- Mag products).
A word about trace minerals. These are crucial to good health, a high energy level and nutrient assimil ation. They also affect the functioning of hormones and enzymes and help protect against toxic reactions and heavy metal poisoning.
All of the premium nutrition in Organic Life Vitamins is combined in a base of organic Noni juice concentrate (a story in itself), and organic whole leaf Aloe Vera juice (a well-known immune booster and, like Noni juice, another nutritional “Swiss Army Knife” with many health benefits).
HOW YOU BENEFIT
Let’s take a Closer look at the vitamins in Organic Life Vitamins and what they do: Vitamin A— p romotes good eyesight, healthy skin, shiny, healthy hair, a strong immune function and more.
Vitamin B complex—O rganic Life Vitamins contains 11 essential B vitamins! The B vitamins are necessary for everything from energy and sleep to a full head of hair!
Vitamin C—necessary for a strong immune system, strong bones and healthy skin. Vitamin D—necessary for the proper formation of bones and helps calcium to absorb properly.
Organic Life Vitamins
Formulated for your lifestyle
Vitamin E—necessary for supplying oxygen to the brain, creating hormones, healthy skin, proper muscular function and more .
Vitamin K—supports natural blood clotting.
Now let’s look at the minerals. O rganic Life Vitamins contains Selenium, Zinc, C h romium, MSM (organic sulfur), and a full spectru m of trace minerals. These minerals are essential for keeping off unwanted pounds, for a sharp mind, and for maintaining a strong immune system.
An exciting plus that comes as part of Organic Life Vitamins is the inclusion of amino acids. Amino acids are the “building blocks” of the body. Besides building cells and repairing tissue, they form antibodies to combat invading bacteria and viruses; they are part of the enzyme and hormonal systems; they build nucleoproteins (RNA and DNA); they carry oxygen throughout the body and participate in muscle activity.
Organic Life Vitamins is the only liquid multi-vitamin that contains 20 different amino acids to help bring you to a whole new level of health.
Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplement
June 21, 2005 05:10 PM
By Adina Licht, MS
Adina Licht, M.S. is a Nutritional Scientist and Science Writer who works as a Marketing Specialist for Source Naturals. She has a B.A. in Environmental Science from UC Berkeley, an M.S. in Nutrition and Food Science from San Jose State University, and training in Technical Communication from Cal State Hayward. Her work has appeared in publications such as Advances in Packaging and Development, Health Supplement Retailer and Delicious Living.
Americans Need More Nutrients
The U. S. population is drastically malnourished. According to the latest A. C. Nielsen survey, only 12% of Americans claim to eat the 5 recommended servings of fruits and vegetables each day (Warner, 2004). And approximately 1/3 of the calories that people do consume are from nutrient-poor foods such as alcohol and soda (Yang, 2004). This combination has led to a population that consumes too few nutrients, which according to an article in the Journal of the American Medical Association (Fletcher, 2002) puts people at risk for long-term health concerns. With Americans eating fewer healthy foods, taking a daily multiple is one way for people to increase their intake of nutrients. But the search for what defines a good multiple can be confusing, even to health care professionals.
The Confusing U.S. Government Standards
Scientists first recognized the need for vitamins in the early 1900s (Levenstein, 1993). But setting U. S. government standards for vitamins and minerals didn't start until healthy soldiers were needed to fight World War II. And when a committee of scientists was asked to determine the levels of nutrients needed to maintain good health they could only agree on "recommended allowances" to prevent deficiency with a wide margin of safety. In 1941, these allowances became the first Recommended Dietary Allowances (RDAs) for the nation (Levenstein, 1993). In 1997, the Food and Drug Administration (FDA) used latest RDAs to set the new Dietary Reference Intake (DRI) standards, which included Adequate Intakes (AIs) for when there was insufficient evidence to determine an RDA, and Upper Intake Levels (ULs) as the safe daily upper limit. To simplify the information, food labels express nutrient information as a percentage of the Daily Value (DV), which includes RDA values for a healthy adult who consumes 2000 calories per day (Whitney, 2002). However, these values do not include AIs or ULs and many individuals need different levels of nutrients than these.
Confusing Standards equals Confusing Recommendations
The RDAs and subsequent DRIs are the basis of the nutrient standards for at least 40 different nations and many professional health organizations. Currently, the American Dietetic Association (ADA) recommends that people who cannot reach the DRIs through diet take a multiple with nutrient levels that do not exceed the RDAs (JADA, 2001). And in 2002, the American Medical Association (AMA) published a paper that included a recommendation for all adults to take RDA levels of vitamin supplements in their Journal of the American Medical Association (Fletcher, 2002). Despite the benefits of having guidelines, most people only hear about the RDAs and DVs, which may be too low for preventing deficiencies while the ULs and AIs, which can be much more beneficial are rarely discussed. For example, the Daily Value of Vitamin E to prevent deficiency is 30 IU while the daily Upper Intake Limit is 1,467 IU. But, according to the ADA, as many as 75% of cardiologists recommend vitamin E to their patients to promote heart health, usually at a dosage of 400 IU (ADA, 2001; Meydani, 2004; & Whitney, 1998). And the Daily Value for Vitamin C is 60 mg while the daily Upper Intake Limit is 2000 mg, but in clinical studies it took 500 mg per day to help maintain healthy blood pressure (Whitney, 1998, & Hendler, 2001).
Lyle MacWilliam is a biochemist and former health advisor to the Canadian Ministry of Health, who decided to research, analyze and publish the Comparative Guide to Nutritional Supplements. In this book, the individually published recommendations from seven nutrition experts (Phyllis Balch, CNC, Dr. Michael Colgan, Ph.D., Dr. Earl Mindell, Ph.D., Dr. Michael Murray, N.D., Dr. Richard Passwater, Ph.D., Dr. Ray Strand, M.D., and Dr. Julian Whitaker, M.D.) were combined to create an ultimate blended standard of recommended median intakes for 39 nutrients to promote health. Those nutrients include vitamins, minerals, phytonutrients, and other supplements, that span 14 different health categories and are much Closer to the Upper Intake Limit government standards. The guide also includes information about recommended forms, safety, purity and quality (MacWilliam, 2003). One of the most profound differences between MacWilliam?s compiled recommendations and the DRIs is the difference in the number of supplements: 39 vs. 26 respectively. The Comparative Guide standard includes additional nutrients, including many more antioxidants, based on decades of clinical research about their benefits. For example, the fat-soluble antioxidant Coenzyme Q10 that your body manufactures less of as you age is included. So is the fat and water-soluble antioxidant alpha lipoic acid that helps recycle other antioxidants such as vitamins C and E (Hendler, 2001).
Top Ranked Multiples for Optimal Health
In the latter half of MacWilliam's book he uses this ultimate blended standard to rank and compare 500 manufactured multiples. Of the five top-ranked multiples, only the Source Naturals multiples, Life Force and Élan Vitàl, are widely available at natural product stores and health outlets. And the new and improved Life Force formulation now rates higher than any of the products evaluated in the current edition of this guide (MacWilliam, 2004; & Mac-William, 2003). The ingredients that can be found in today's multiple supplements can vary greatly. But multiple choices don't have to lead to confusion. Health professionals, such as Lyle MacWilliam, understand the importance of remaining curious, evaluating the available research, and conferring with other scientists to determine the nutrients that support optimal health.
American Dietetic Association. 2001. Vitamin E: Disease Prevention for your Good Health. American Dietetic Association Website. Available at: Public/Other/index_nfs1001.cfm Fletcher, R. H., & Fairfield, K. M. 2002. Vitamins for Chronic Disease Prevention in Adults. JAMA. (23)287:3116-3129. Hendler, S. S., et al. 2001. PDR for Nutritional Supplements. Thomson Healthcare: Montvale. Pages 11-12, 17-21, 60-62, 103, 416-421, 486-498. JADA (Journal of the American Dietetic Association) 2001. Vitamin and mineral supplementation. J AM Diet Assoc.101: 115 Available at: Public/NutritionInformation/92_8343.cfm Levenstein, H. 1993. Paradox of Plenty: A Social History of Eating in Modern America. Oxford University Press: New York. Pages 13-15, 64-67. MacWilliam, L, et al. 2003. Comparative Guide to Nutritional Supplements. Northern Dimensions Publishing: Vernon. Pages 62-70. MacWilliam, L. 2004. Comparative Guide Individual Assessment of New Life Force Formulation. Warner, J. 2004. Few Follow '5 a Day' Fruit and Vegetable Rule. WebMD website. Available at: ent/Article/93/102158.htm Whitney, N. W., & Rolfes, S. R. (1998). Understanding Normal and Clinical Nutrition, 5th ed. Page 358. Whitney, E. N., & Rolfes, S. R. 2002. Understanding Nutrition. 9th ed. Wadsworth Thomson Learning: Belmont. Pages A, B, Y, 13-20, 55-56, 307, 331, 335-341, 401. Yang, S. 2004. Nearly one-third of the calories in the US diet come from junk food, researcher finds.
June 14, 2005 06:11 PM
by Charles Scott Energy Times, January 4, 2005
If you want to stave off infections, aging-even liver cancer-get your fill of chlorophyll, a vital nutrient in plants.
The green in plants possesses unique powers. Green landscapes soothe the soul. A verdant expanse of green vegetation offers comfort, peace and ecological consolation. What makes some plants, including vegetables, green: Chlorophyll, a substance that is also a crucial nutrient for better health.
Chlorophyll is a special chemical that consists of molecules which enable plants to collect sunlight. In a complex molecular process, vegetation then uses chlorophyll to harness the power from the sun's rays and build carbohydrates from carbon dioxide and water. Those carbohydrates form the basic nutritional building blocks that we and other animals need to survive and thrive.
Besides enabling the creation of carbohydrates, research shows that chlorophyll itself can help lower our risk of diseases like cancer. A recent study in China demonstrates that daily supplements of a chemical derived from chlorophyll can protect DNA, the genetic material in cells. When DNA is damaged and malfunctions, cells may reproduce wildly and become cancerous tumors. The latest experiments, performed by scientists affiliated with the Johns Hopkins Bloomberg School of Public Health and Oregon State University (OSU), show that chlorophyll and its chemical relatives may insulate DNA from unhealthy changes linked to aflatoxin, a fungus that often contaminates corn, peanuts and soybeans. In China, liver cancer associated with aflatoxin is a widespread problem.
" In the area of China in which we did our study about one in 10 adults die from liver cancer, and it's the third leading cause of cancer deaths worldwide," says George Bailey, PhD, a professor of environmental and molecular toxicology at OSU. "The findings of this research could be enormously important to many areas of China, Southeast Asia and Africa, where aflatoxin-related liver cancer is a real concern. Many of these deaths might be preventable with supplements that cost pennies a day."
This research looked at about 180 people in Qidong, China. When people in the study were given supplements containing chlorophyll derivatives, they had less than half the DNA damage of people who didn't take supplements.
According to the scientists, chlorophyll and similar substances may act as interceptor molecules, blocking the absorption of carcinogens. As John Groopman, professor at the Johns Hopkins School of Public Health, observes, the supplements these people took "...can effectively reduce aflatoxin levels, which should reduce the risk of liver cancer."
Closer to home, other researchers point out that chlorophyll-rich vegetarian foods may help protect us from carcinogens in the typical American diet.
If you've ever enjoyed a hunk of grilled meat, you've consumed substances scientists call heterocyclic amines, which are contained in the charred part of meat cooked on a grill. Studies have shown that these tasty tidbits can increase your risk of breast and other types of cancer. (Your risk from charred meat greatly increases if you are also a smoker.) However, if you eat a food like spirulina, a blue-green algae high in antioxidants that also contains plenty of chlorophyll, its protective substances can bind with these carcinogens within your digestive tract and keep them from being absorbed.
Green Keeps You Younger
While we always hear that eating more fruits and vegetables enhances our health, new research shows that eating green foods adds extra power to an anti-aging program.
Two experiments at the University of South Florida Center for Aging and Brain Repair, published in the Journal of Neurobiology (7/15/02), show that spirulina and other greens can help shield the brain from the antioxidant damage that accumulates as one ages and may help reverse declines in learning and memory.
The first study found that a diet rich in spinach helped lab animals stay smart as they grew older. Spinach's benefits, according to the researchers, are due to its rich antioxidant content, which can counteract free radicals (caustic molecules) created in the body during normal metabolism and increased by exposure to environmental pollutants, sunlight and radiation. When free radicals attack, cell walls and other cellular structures are compromised and DNA can malfunction. A lifetime of free-radical damage can slow your thinking and may be one of the causes of Alzheimer's and Parkinson's diseases, says Dr. Paula Bickford, lead author on the project.
The second study found that the protective effect of green plants may be linked to their ability to reverse age-related accumulations of potentially harmful inflammatory substances in the brain. In this research, spirulina improved neuron function, lowered inflammation in the brain and reduced levels of chemicals linked to oxidative damage. In fact, spirulina didn't just slow the deterioration of neurotransmitter interactions caused by aging, it actually improved their function.
" Not all foods are created equal," says Dr. Bickford. "Cucumbers taste good and have lots of fiber. But unlike spirulina and apples, they are not rich in phytochemicals that have antioxidant or anti-inflammatory effects in the brain."
Aside from assisting brain function, spirulina also seems able to help pump up the immune system. Researchers at the University of California at Davis found that adding spirulina to cultured immune system cells significantly increases the production of infection-fighting cells called cytokines.
A number of previous laboratory studies have found that spirulina can balance immune response: While easing allergic reactions, this powerful green food also was found to enhance the ability of immune cells called macrophages to both destroy bacteria and eliminate cancerous cells.
" We found that nutrient-rich spirulina is a potent inducer of interferon-g (13.6-fold increase) and a moderate stimulator of both interleukin-4 and interleukin-1b (3.3-fold increase)," notes Eric Gershwin, professor at UC Davis. "Together, increases in these cytokines suggest that spirulina is a strong proponent for protecting against intracellular pathogens and parasites, and can potentially increase the expression of agents that stimulate inflammation, which also helps to protect the body against infectious and potentially harmful micro-organisms."
What this means for you: Spirulina holds the potential to help the body protect itself against battalions of infectious invaders. " People have used foods like yogurt and spirulina throughout history," says Judy van de Water, PhD, associate professor at UC Davis. "Through research, we are learning exactly how these foods improve immune system function and how they are a beneficial addition to our diet."
Throughout the history of life on earth, the healthy development of animal and human life has depended on green plants. Today, as our environment deteriorates and our bodies are under attack from an increasingly polluted world, we need those health-boosting greens more than ever.
Truth in Labeling
June 14, 2005 10:44 AM
Truth in Labeling by Diane Stanton Energy Times, June 14, 2004
Do you or don't you read food labels when you shop? If you don't, you're missing out on a prime source of information about your meals. If you want control of your health, focus on package labels and pick your foods carefully.
The large print on food labels focus on what are called macronutrients: carbohydrates, fat and protein. Some of the smaller categories convey information about vitamins, fiber, and minerals, as well as the totals of fat and saturated fat contained in food. So, you have no excuse for claiming ignorance about your diet: the truth is in the labels.
Food labels can be confusing to the uninitiated. Go into a big food store and you can be faced with what seems to be a forest of food information: more than 15,000 labels. Add to that fact that every year more than 30,000 new food products can be introduced to the marketplace, and what you're faced with is a jungle of food labels.
That overwhelming wealth of food label information doesn't mean you should throw up your hands in dismay and give up reading and deciphering labels. You should arm yourself against that sea of labels with knowledge and, by understanding them, end your confusion and build your health.
A hundred years or so ago, food labels were only required to list the name of the food contained inside the package. The contents, quality and processes used to make the food were often a mystery. Little or no disclosure to consumers was made about how their food was created.
By the early 1920s, the federal government, via the Food and Drug Administration (FDA), began requiring food companies to list the net weight of food on labels as well as the names and addresses of food processors and distributors. Finally, by the 1970s, listing basic nutritional information was mandated in a uniform way so that shoppers could have some basis for comparing foods. Then, in 1990, the Nutrition Labeling and Education Act made major alterations to the kinds of labels that had to be included on food packages.
The FDA and the US Department of Agriculture (USDA) required significant changes to food labels that were supposed to make it easier for consumers to eat healthier diets. The labels requirements of 1994 included five major changes:
Consumer questions regarding food labels have led researchers to look into ways to help shoppers comprehend what food labels tell them. These studies are designed to help consumers match up their nutrition requirements with the foods they buy.
For instance, at the University of Illinois at Urbana-Champaign, scientists have devised a label tool called See It, Do It, Teach It to help people improve their diets through comprehension of food label information. " One of the goals of the project was to help...teenaged girls and menopausal women understand how they can get the daily requirement for calcium into their diet in order to help prevent osteoporosis," says Karen Chapman-Novakofski, PhD, associate professor and nutritionist in the school's College of Agricultural, Consumer and Environmental Sciences.
According to the See It, Do It, Teach It program, you should think of food labels as consisting of two sections:
" Much more attention has been paid to what people should limit rather than the nutrients needed. The average consumer doesn't know, for instance, how much vitamin A 10% of the Daily Value is, or how much calcium 25% of the Daily Value is," Dr. Chapman-Novakofski says.
Upping Calcium Intake
In their eight-week study of people's calcium consumption (Journal of Nutrition Education and Behavior 4/04), the University of Illinois research team found that people didn't know how much calcium was in the food they ate.
After the initial part of the study, in which participants were shown how to look for calcium on labels, "the post-test revealed that the participants significantly increased their calcium intake to 821 mg per day, up from 372 mg per day," notes Dr. Chapman-Novakofski.
" That's a lot Closer to the daily requirements of 1,200 mg per day for men and women over 50, 1,000 mg for men and women aged 19 through 50 and 1,300 mg per day for [youths aged] 9 to  years," she adds.
Parts of the Label
The first item at the top of a nutrition food label tells you the portion size that the label measures. An important point to remember: these sizes are determined individually by each manufacturer. Consequently, all of the other values on the label are measured per portion.
So, if you are comparing foods made by two different companies that employ very different portion sizes in their nutritional calculations, your label comparisons may be complicated.
Another fact to be aware of: the listed portion size may be an odd division of the food within the container and not reflect a common-sense division. For instance, some food packages are labeled as containing 2.5 portions.
And, to make things even more interesting, small boxes of candy that you might think contain barely enough for one helping may be labeled by the manufacturer as having two or more portions. As a result, if you eat the whole box, you often have to at least double the number of indicated calories, etc. to figure out the nutrients and calories you are consuming.
The section of the label that notes calories, calories from fat and percent daily values is listed under the portion size. Here you are told how many calories you consume when you devour one portion and how many of those calories are derived from fat.
This label focus on fat originated when consumers and dietitians were very concerned about Americans' fat consumption and hadn't yet switched their focus to carbohydrate consumption as a prevalent dietary health priority.
Also included on the label: the daily value percentages aimed at showing you how much out of a total day's intake of various nutrients a portion bestows upon you.
These percentage numbers are based on a theoretical analysis of a diet that contains 2,000 or 2,500 calories a day. (A notation at the bottom of the label tells you whether the calculation is based on 2,000 or 2,500.)
If you've been eating a low-carb diet (or are planning this type of diet), the section of the label that lists carbohydrates may be especially useful. Under this heading, the label lists the totals for fiber and sugar.
No matter what diet you are on, dietary fiber is desirable, since it represents indigestible carbohydrates that both pass through you without conveying any calories and keep beneficial bacteria in your digestive tract healthy.
Most people want to limit their sugar totals, however, since this nutrient may raise your risk of being overweight and, when you eat a lot of it, may contribute to immune problems.
Interestingly enough, when food chemists compute what is in food, they perform lab tests known as assays to distinguish its ingredients. (The manner in which these tests are performed are very strictly regulated by the FDA.)
In fact, just about every nutrient listed on a food label is determined by laboratory test except for the carbohydrate content: the amount of water, fat, crude protein and ash are determined this way. But the total carbs are computed by simply subtracting the total of the other ingredients from the total amount of food, a kind of process of elimination.
So while fat and protein are measured with precise lab tests, carbohydrate totals are figured by the leftovers. (The water and ash, by the way, are not usually listed on food labels.)
Within the general carbohydrate group, are several categories of carbohydrates that produce very different effects in your body. These categories can be divided into sugar, sugar alcohols, dietary fiber and a collection of various chemicals that include organic acids, flavonoids, gums, lignans and others.
According to the FDA, the food label only has to list the total carbs, sugar and dietary fiber. But some food companies now list things like sugar alcohols.
Blood Sugar Effects
Not all of these types of carbohydrates behave the same way in your body. For example, when your body digests table sugar, it turns immediately into blood sugar. So sugar and most other carbohydrate is what we call "digestible carbohydrate." Other carbs, such as sugar alcohol or glycerine, can be digested but do not turn to blood sugar. Still others, such as dietary fiber, are indigestible and pass through your body without impacting your blood sugar level.
To date, the FDA has not focused on these important biochemical differences and treats all carbohydrates alike. This means that when you look at a food label, you do not see a number for the carbs that impact your blood sugar level. To do so, simply subtract the number of grams of fiber from the total number of carbohydrate grams.
Recently, the phrases "low carb," "net carb" and "impact carbs" have begun to appear on food labels. These are not defined by the FDA; they were put on labels by by companies to help consumers pick out foods that are acceptable on low-carb diets. To arrive at the total of net carbs, food companies subtract the total amount of fiber and sugar alcohol from the total carbohydrates.
Since the body cannot digest fiber, this nutrient (which is still important for good health) is not calculated into the total amount of carbohydrates. As for sugar alcohols, while-technically speaking-these are carbs and they do have calories, they have little effect on blood sugar and usually are not counted in total carbohydrates.
According to the American Dietetic Association, people with diabetes who are managing their blood sugars using the carbohydrate counting method should "count half of the grams of sugar alcohol as carbohydrates since half of the sugar alcohol on average is digested.
" Fiber is not digested, however. If the serving of food has more then 5 grams of fiber one should subtract the grams of fiber from the total carbohydrate grams." As you can see, when it comes to food, as in most things, knowledge is power. If you want power over your health, you need power over the food you eat. The road to that power is by reading food labels. What's in the food you're eating every day may surprise you.
SPA: Satisfying Personal Attention
June 14, 2005 10:32 AM
SPA: Satisfying Personal Attention by Sylvia Whitefeather Energy Times, October 12, 2004
Feeling stressed out? Looking for some time to relax and cool off, but just too busy to get away? Give yourself a spa treatment at home.
Creating your own home spa experience is easy and the benefits are many. With some common household items and a few essential oils, you can luxuriate in your own special spa experience while recharging and renewing mind, body and spirit. Indulge with a few close friends for a unique, shared experience.
Using concentrated plant oils derived from flowers and plants, aromatherapy offers an ancient healing art that has gained newfound respect in the modern world. Aroma chemicals transfer quickly into the body, and researchers are finding unique ways to employ this ancient technique, including medical applications.
Studies find that lemon balm or lavender oil reduces behavioral problems in older people with dementia (BMJ 2002; 325:1312-3). Rosemary has been found to improve memory and enhance mental functioning (Int J Neurosci 2003 Jan; 113(1):15-38).
Only a drop or two of an essential oil is needed to receive their unique healing benefits. (Always dilute essential oils; never use or apply them directly to your skin without watering them down.) Essential oils can help you relax, rejuvenate, improve your memory and increase your energy.
Some essential oils are reputed to reduce pain, kill bacteria, speed healing of injuries and help fight inflammation and infection (Natl Meeting, Amer Chem Soc, 8/02).
When you feel like you're ready to spa, take the phone off the hook, unplug the TV and set aside a special, unbothered time and day for your at-home spa experience. Next, turn your bathroom into your special place. Light fragrant candles, put on your favorite soft music and fill the tub.
When running the water you should select a water temperature that fits the effect you desire, according to Valerie Gennari Cooksley, RN, author of Healing Home Spa (Penguin). Water temperature that approximates your normal body temperature produces a sedative effect. On the other hand, hotter water-that which hovers around 100 degrees-induces sweating and helps cleanse and detoxify. In any case, limit your time in hot water to about 20 minutes. If you use cold water, only stay immersed for a few short minutes to rejuvenate and close the skin's pores.
Try adding about 10 drops of either lavender or ylang-ylang oil to a warm bath to aid in relaxation and to release tight muscles. Don't rush; soak for at least 20 minutes and let the fragrant water vaporize your cares. Dry off with a fluffy towel and wrap yourself in your favorite bathrobe.
Other bath enhancers you can add to your soak include oatmeal to soften the skin, seaweed for deep cleansing, Epsom salts to relieve aches, and baking soda to alkalize the body. Herbal sachets can be made by placing dried herbs in a muslin bag and dropping the bag into the water to release fragrances and healing chemicals.
The facial is a standard spa procedure. Hold your face over a steaming bowl of hot water that contains lemon juice or a few drops of lemon essential oil for about 15 minutes. Use a towel over your head to hold in the steam.
When your face is well moisturized, apply a facial mask. On dry skin, use either puréed, ripe avocado or a mask of honey and kelp. If your face is oily, apply either puréed, ripe bananas or a mask of peppermint oil and honey. If you are not sure of your skin type or have mixed skin, green clay can be used for a balanced facial. Green clay is rich in minerals while being antiseptic and healing, notes Valerie Ann Worwood, author of The Complete Book of Essential Oils and Aromatherapy (New World Library). With the addition of warm water, it creates an instant facial mask. (You can also use prepared facial masks; ask about them at your health food store.)
To apply the mask, begin at the forehead using upward strokes. Go easy around the eyes. Afterwards, put cucumber slices over your eyes and relax. Keep the mask on for about 15 minutes. Wash your face with warm water and then apply a moisturizer. Your skin should feel supple and look radiant.
Worwood recommends a few drops of rosemary oil and one tablespoon of baking soda in a basin of warm water to soothe your feet. Soaking your feet for about ten minutes softens the skin and nourishes the nails. After drying off, combine one-half cup sea salt with one-half cup of cooking oil, preferably olive, canola or sesame. Gently massage into each foot to stimulate reflex points and remove dead skin. Rinse and pat dry. Finish with a pedicure.
This salt scrub can be used on any part of the body to eliminate toxins, increase circulation, improve lymphatic movement and cleanse the pores. A popular European treatment, it is especially helpful for parts of the body that store water, such as the tummy and thighs. Rinse completely after the scrub and apply moisturizer to dry areas.
Since hands can age quickly, Worwood suggests using oils of rose, sandalwood and geranium for dry or neglected hands. You can also mix one-half cup of sugar with one-half cup cooking oil and a few drops of one of the above essential oils. Massage into each hand to moisturize and pamper your overworked hands. Rinse and apply your favorite lotion to seal in moisture. A gentle manicure adds the finishing touch.
Your special spa day wouldn't be complete without pampering your hair. Noted dermatologist David Bank, MD, suggests looking for shampoos that contain such gentle cleansers as avocado, borage oil, grapeseed oil, sunflower oil and wheat germ oil. Your shampoo should also contain moisturizing substances, such as aloe vera, to help give your locks shine and bounce.
Check your hair's condition. Oily hair-that which feels greasy within a day of washing-responds best to frequent washing with minimal conditioning. A bad case of the frizzy tangles is a sign of dry hair, which needs a moisturizer-rich shampoo.
Revive From the Inside With Green Drinks
During your spa day, sip green drinks. Green drinks made from aquatic plants such as spirulina, seaweed and kelp contain needed minerals to nourish skin, hair and nails; these plants have been used for centuries to promote health and longevity. In addition to being high in minerals, they are also low in fat, high in fiber and rich in protein.
The marine vegetables found in green drinks help detoxify the body, support the lymphatic system, alkalize the blood and tissues, and support a healthy thyroid. Many natural food stores carry green drink powders that can be added to juice or water. Sipping on a green drink can enhance the cleansing action of your home spa treatment, balance blood sugar levels and maintain your energy level during the day.
Throughout your home spa experience, drinking spring water with a touch of lemon or lime can facilitate the elimination of toxins and keep you hydrated. Indulge in plenty of high-fiber fruits and vegetables, and avoid processed sugars and high-fat foods. Eating lightly allows your body to eliminate toxins from the inside out while you work on the outside.
As Valerie Cooksley says, "...sound health occurs when the mind, body and spirit are in perfect harmony and balance." A home spa experience takes you a step Closer to that harmony.
June 10, 2005 09:37 PM
Diabetes by , February 5, 2002
Lack of exercise and being overweight boosts your chances of developing diabetes. So, as America's epidemic of obesity grows, the number of people afflicted with the condition called type II diabetes is expected to soar. If you follow the typical US pattern of not getting enough exercise while indulging in a diet of too many calories from cookies, cakes, fast food and saturated fat as your waistline gradually expands, your chances of encountering this health menace grow every day. According to the most recent estimate by health researchers, "more than half of all US adults are considered overweight or obese"(JAMA, 10/27/99).
Those same researchers, who examined the health history and weights of more than 16,000 Americans, confirmed a fact well-understood by health practitioners who understand the chemistry of blood sugar: being overweight greatly increases your chances of not only diabetes but also high blood pressure, gall bladder disease, coronary heart disease, high cholesterol and arthritis. (If you suffer or think you suffer from diabetes, or any of these conditions, consult a knowledgeable health practitioner.)
While Type I diabetes is a relatively infrequent disease that often strikes kids, Type II diabetes is a much more widespread (and increasing) health problem experienced by 9 out of 10 adults with what is now called adult-onset diabetes.
The popular image of someone with diabetes is, ironically, often of someone who is suffering with Type I. In simplistic terms, Type I diabetes occurs when your pancreas stops producing insulin, a hormone-like substance that, among its several tasks, helps deliver sugar from the bloodstream into the body's cells. When your body is functioning normally, insulin helps steady blood sugar levels and keeps tissues fed with nutrients.
People with Type I diabetes often have to inject themselves with insulin. Otherwise, a lack of insulin causes dangerously increased blood sugar levels, cellular damage to blood vessels and nerves plus a high risk of heart attack, blindness, kidney failure and serious damage to your extremities that may, in the long-term, lead to amputation.
On the other hand, someone beginning to suffer Type II diabetes usually has plenty of insulin being produced by the pancreas, but may be insulin resistant: for a variety of physiological reasons, the hormone is unable to do its job. That allows blood glucose to reach levels where it can wreak metabolic havoc.
When you gain weight, drastically increase the amount of your bodyfat and lead a sedentary, couch potato existence without engaging in very much exercise, you boost your risk of becoming insulin resistant. Consequently you also boost the chances of eventually suffering Type II diabetes.
However, a consistent exercise program (and losing weight) can alleviate or moderate some of the blood sugar problems brought on by diabetes or insulin resistance. When you exercise, your working muscles may take in more glucose from the bloodstream and stabilize your blood sugar level. That is one reason physical exercise helps to modify your body's response to blood sugar. (Of course, if you have diabetes or have not exercised in a long time, be sure to consult your health practitioner before engaging in strenuous physical activity.)
One of the most useful supplements employed to help control diabetes is chromium, a mineral that plays an integral role in the body's metabolism of sugar.
In the Natural Health Bible, Steven Bratman, MD, and David Kroll, PhD, discuss a study in China of 180 people with Type II diabetes. In that study, those who took chromium enjoyed better blood sugar levels than the people who took no supplements (Diabetes 46(11): 1786-1791, 1997). In addition, a double-blind study of chromium found that the supplement could reduce the necessary oral medication by more than half in many cases (Harefuah 125(5-6): 142-145, 1993). In this study, women seemed to benefit from chromium more than men.
Relief with Alpha Lipoic Acid
Alpha lipoic acid, an antioxidant nutrient, helps defend nerve cells against painful damage-a condition called neuropathy-that can result from diabetes. Consequently, in Germany, doctors have been prescribing lipoic acid to people with diabetes for more than two decades.
According to Dr. Bratman and Dr. Kroll, studies show that lipoic acid may be particularly helpful when taken with gamma-linolenic acid (GLA), a fatty acid found in evening primrose oil and borage oil. Studies of GLA have found that this fat can soothe numbness and pain and slow nerve injuries (Diabetes Care 16(1):8-15, 1993).
Taken together, GLA and lipoic acid may synergistically improve nerve function (Diabetologia 41(4): 390-399, 1998). Blood sugar control may also improve.
Two signs that you may be suffering diabetes are excessive thirst and a dry mouth. This missing liquid, especially in the mouth when the flow of saliva slows, can lead to a lack of lactoferrin, a naturally-occurring protein that fights infection in the mouth by binding iron (Jrnl of Diab Comp 7, 57-62).
Lactoferrin's iron-binding ability destroys harmful micro-organisms like bacteria. In addition, lactoferrin stimulates the body's production of a substance called secretory IgA, which keeps disease-causing organisms out of the body and helps stabilize blood sugar (colostrum also produces this effect).
Fenugreek, a spice, has had long use as a medicine and food ingredient in the Middle East and Asia. And now modern science has begun to accumulate evidence supporting its traditional use: Several studies have shown that this seed can benefit blood sugar levels and keep blood cholesterol down.
In laboratory animals, researchers found that fenugreek kept blood sugar levels under control and also increased HDL (good cholesterol) while dropping triglycerides, blood fats that increase the risk of heart disease (Eur Jrnl Clin Nut 44 (1990):301-306).
Fortuitously, studies on people have supported fenugreek's benefits. In people with Type I diabetes, studies show that fasting blood sugar levels were reduced and glucose tolerance tests (measures of how well the body handles sugar) were Closer to normal (Eur Jrnl Clin Nut 42 (1988):51-54). Bilberry for Eye Health
Retinopathy, eye damage resulting from diabetes, is a serious complication of this disease and can cause blindness. Bilberry, a botanical that has been used as a folk treatment for eye health for centuries, may be able to lower the risk of this kind of vision destruction.
Bilberry, a dark berry that grows in Europe, has been shown in a collection of laboratory tests to hold down blood sugar levels (Quart Jrnl Cr Drug Res 17(1979):139-196). Bilberry has traditionally been used to protect eyesight.
According to the Encyclopedia of Natural Medicine (Prima), natural substances called flavonoids, found in bilberry, "have been shown to increase intracellular vitamin C levels, decrease the leakiness and breakage of small blood vessels, prevent easy bruising and exert potent antioxidant effects."
Apparently, the body uses these flavonoids to protect the eyes' blood vessels and to keep the retina (central part of the eye crucial to preserving sight) functioning normally (Arch Med Int 37 (1985):29-35). Consequently, bilberry has been used by health practitioners in France to treat diabetic retinopathy ever since the 1940s.
As medical researchers look more closely into how insulin functions throughout the body, much more light will be thrown on how supplemental nutrients and your diet interact to promote the healthiest blood sugar levels.
But, today, what we already know about how the body functions can help you: a low-fat, high fiber diet, moderate, consistent exercise and healthy doses of insulin-friendly supplements may help keep your blood sugar under control.
And keep those pounds from accumulating around your waist. That way, you can keep from singing that nasty old, down and dirty, blood sugar, syncopated ragtime blues.
June 10, 2005 03:24 PM
by Henry Wolfe Energy Times, July 11, 2003
Nutrients do you no good if you don't absorb them. Eating the right stuff and taking the right nutrients can still be wrong if they never make it out of your digestive tract and into your bloodstream.
For instance, dietary supplements usually should be taken along with food. The presence of food in the digestive tract aids the absorption of nutrients. As a general rule, if you take dietary supplements on an empty stomach, most of their contents will probably pass through you and never escape your intestinal tract before they are eventually eliminated. This is particularly true for the fat-soluble nutrients such as vitamins A, D and E. By consuming fatty foods when you take these supplements, you enable your body to absorb a large amount of these valuable substances.
But there is at least one exception to this rule: Amino acid supplements (protein building blocks) should usually be taken on an empty stomach. Otherwise the other amino acids present in your meal may interfere with your use of these nutrients and counteract the benefits of the supplements.
The Standardization of Herbs
Taking herbs presents different challenges than consuming dietary supplements. While the chemical structures of nutrients in supplements are usually precisely identified, the active ingredients in herbs is usually a mixture of chemicals. Often, too, researchers disagree on exactly which active ingredients in herbs produce the health benefits linked to these botanicals.
But in an effort to derive the most from these substances, many experts recommend what are called standardized forms.
Standardized herbal supplements are formulas that have been created to insure they contain consistent and reliable amounts of certain beneficial chemicals that scientists have identified in these plants.
In the creation of these supplements, experts determine the standardized chemicals that are most likely the basis of the herbs' effectiveness.
By standardizing certain of the supplements' ingredients, therefore, standardized herbs limit the variation among batches of the product. You can rely on the fact that every purchase will contain the same amount of ingredients taken from the original plant. According to Michael Janson, MD, author of Dr. Janson's New Vitamin Revolution (Penguin/Avery), "Although herbs have a long history of use for medicinal purposes, it is only recently that they have been analyzed to reveal their most active components. These active chemicals are commonly present in very variable amounts in herbs, depending on where and how they are grown, soil quality, when they are harvested, the amount of rain and sun, and other factors.
"Standardized herbs have guaranteed specific amounts of the known, active herbal components, as well as the other factors that might be of help but are not as well studied" (www.drjanson.com).
Herbalists who specialize in using entire plants in their practices can recommend non-standardized preparations that you can often use.
In general, that kind of herbal use is more effective when you secure expert advice. If you lack access to an experienced herbalist and you're choosing botanicals on your own, standardized preparations are easier to take.
Absorption From the Gut
Most of the nutrients you take in are absorbed through the walls of your digestive tract. This most often takes place in the small intestine.
What to watch out for: Fast food, fast living and long work hours afflicts our digestion and can disrupt proper absorption. You have to be relaxed to properly absorb the nutrients in your food and supplements.
Consequently, the occasions for meals should be relaxed and enjoyable moments. Set aside enough time to appreciate, taste and thoroughly chew your food. Adequate digestion and absorption begin in your mouth.
Another way to increase nutrient absorption is with the use of digestive enzymes. Since the digestive tract depends on the enzymatic breakdown of food that reduces nutrients to absorbable form, taking enzymes can help your intestines make better use of nutrients as they pass through the digestive tract. Normally, enzymes are present in raw food, like uncooked fruits and vegetables. Since most of our food is eaten after it is heated, a process that breaks down enzymes, not many enzymes are present in today's diet. Therefore, taking supplemental enzymes may increase absorption.
Beyond everyday stress, a variety of problems can make absorption go astray, allowing important nutrients to escape and permitting unwanted substances to enter the body. For instance, a significant digestive malfunction that many experts have focused on in recent years is a condition that has come to be called "leaky gut."
As Anil Minocha, MD, director of digestive diseases at the Mississippi Medical Center and author of Natural Stomach Care (Avery), points out, "In a healthy individual, the wall of the intestinal tract is designed to absorb food molecules and prevent harmful microorganisms and toxic materials from passing out through the bowel wall and into the bloodstream. "In today's heavily polluted environment, the gastrointestinal tract of even the healthiest individual is called on to process an overwhelmingly large flow of septic and infectious materials."
Because of these digestion destroyers, as we take in a startlingly large amount of viruses, bacteria, toxic chemicals, fungi and processed foods, our digestive systems are often overwhelmed and are rendered unable to perform their tasks correctly. This constant assault on the stomach and intestines takes a serious toll. A frequent product of this process is the digestive walls' loss of their crucial ability to keep out unwanted toxins and organisms as they become, in Dr. Minocha's words, "loosened and inflamed." As a result, instead of keeping out harmful substances and absorbing helpful nutrients, spaces open up that begin to allow in "bulky, partially digested food particles, toxic substances and infectious microbes."
According to Dr. Minocha, the first signs of this absorption problem can include complaints such as allergic reactions, skin problems, joint pain, digestive difficulties, nausea, fatigue and lack of energy.
To improve your digestive absorption, Dr. Minocha recommends a six-part program that includes these steps:
* Detoxification by means of fasting and avoiding harmful items like sugar, over-processed foods, coffee and alcohol
* Taking herbs that can help the digestive tract heal, recover and repair itself; these include garlic, ginger and milk thistle
* Replenishing the beneficial bacteria of the digestive tract by eating yogurt
* Keeping track of your daily diet and eliminating foods that cause allergies and other reactions
* Consuming more fruits and vegetables while eating a high-fiber, mostly vegetarian diet
* Developing consistent, healthy lifestyle habits; these include not smoking, cutting the size of your meals and eating in moderation, exercising several times a week and controlling stress
Young and Old Digestion
The nutrients in your diet can also beneficially influence the state of your digestive system and its ability to distinguish among substances that are supposed to gain entrance to your body and those that should be kept out. Since aging can further compromise the discriminatory ability of your gut, Dr. Minocha also recommends a steady diet of antioxidant-rich fruits and vegetables plus supplements to keep your digestive tract functioning at full capacity as you grow older.
Among the nutrients he recommends:
* Coenzyme Q10: By middle age, your body makes less of this powerful antioxidant that helps cells generate energy in the mitochondria (structures within cells that may decrease with age).
Dr. Minocha notes that research demonstrates CoQ10 may be able to help people with diabetes control harmful metabolic byproducts that appear in their bloodstreams.
* Natural Lycopene: This antioxidant, responsible for the red of both tomatoes and watermelon, has been shown to lower the risk of both heart disease and prostate cancer. As an antioxidant, natural lycopene also helps protect the digestive tract.
Absorption of the proper nutrients may be the key to health for many people. By paying Closer attention to the well-being of your digestive tract and practicing lifestyle habits that promote maximum absorption, you may be able to substantially improve your nutrition and your health.
Muscle Mass - Reach Your Maximum Muscle Potential
June 04, 2005 09:49 AM
The serious athletes of today know how much it takes to fulfill their competitive goals: careful training, a strong will, and also the right kind of nutrition. Sports science now makes available key nutrients which help assure that strenuous workout regimes will show results. Results that are both nutritionally sound and dramatically visible, without the need for dangerous steroids or chemicals. MUSCLE MASS™ is such a state-of-the-art sports science formula.
THE PURPOSE OF MUSCLE MASS ™ is to help translate distant goals for greater strength and power into quicker, awesome reality. It is the premier formula combining all essential nutrients known to maximize muscle development and optimize strength.
In sum, all these balanced, cutting-edge factors combine to assist you in meeting the challenges you’ve set for your body. Power, endurance, strength, tone, and the winner’s circle are now Closer.
Mega H- Hydrogen (H-)The Fuel of Life
June 03, 2005 05:00 PM
Our universe is composed of millions of compounds, all derived from just 106 atoms. Of these elements, hydrogen is the first and most fundamental.
Hydrogen is also the most abundant element, comprising 90% of all atoms in the cosmos. In our sun and stars, hydrogen nuclei fuse to produce helium, the second element. This generates the enormous energy that powers life on earth. And just as hydrogen fuels the sun, so, in the human body, it is the essential factor in the electrochemical process that produces ATP, the energy molecule. Virtually all the millions of biochemical processes that occur every second of our lives are powered by ATP. These facts are well established. But they are so basic that, until now, they have been overlooked in the world of nutritional science. It took the dedicated research of Dr. Patrick Flanagan to harness the power of active hydrogen for health and human development.
Introducing a revolutionary breakthrough in the field of nutritional science: MEGA H-™ Active Hydrogen (H-), the Fuel of Life.
The Creation of Mega H-
For 30 years Dr. Patrick Flanagan’s life work has been to discover the health and longevity secrets of the Hunza people of the Himalayas. It is believed a much greater percentage of people there live past the age of 100, with far less of the diseases that ravage the West. The locals claimed that their secret was the cloudy, mineral-rich water that rushes down from the Himalayan glaciers. In studying the properties of this Hunza water, Dr. Flanagan found that silica crystals dissolved in the water were able to hold negatively charged hydrogen ions (H-). These compounds are technically called silica hydrides. This makes Hunza water a power source, filled with the same active H- that powers the human body.
Typically hydrogen has one positively charged proton in the nucleus and one negatively charged electron orbiting the nucleus. The two opposite charges balance each other, resulting in no charge. Active hydrogen, on the other hand, contains two electrons orbiting the nucleus, creating a negative charge. It is this active hydrogen in its charged form that the body needs to carry out its crucial functions. Dr. Flanagan has recreated this silica hydride compound as MEGA H-™.
Cellular Energy: ATP, Hydrogen and Mega H-™
ATP, adenosine triphosphate, is composed of three phosphates. The breaking of the bond between the second and third phosphates releases the energy to power virtually all cellular processes. Amazingly, we all generate enough metabolic energy to produce our own body weight in ATP every day just to function! Every second, each of our approximately 50 trillion cells consumes and regenerates 10 million molecules of ATP.
This massive energy generation (ATP production) is the fundamental core function of every human cell. Without it, basic activities such as cellular repair, and protein, enzyme, hormone and neurotransmitter synthesis would not occur. DNA repair and cell reproduction would cease. Thoughts, feelings, communication, and our ability to experience the world through our senses and change it through our actions would stop. The negative implication of poor energy generation for our health and vitality levels is significant. Many factors such as aging, poor nutrition and pollution can impede this critical energy generation. Negatively charged electrons from hydrogen are the source of the energy needed to generate this staggering amount of ATP. This energy production takes place in the mitochondria of the cells at the final stage of the Krebs Cycle, called the electron transport chain. Typically, the hydrogen comes from the breakdown of carbohydrates from food, which yields hydrogen as well as carbon and oxygen. But MEGA H-™ is an alternative, electron- rich source of hydrogen to power energy generation. In fact, MEGA H-™ has been shown to double the production of ATP and NADH, according to in vitro studies. (NADH is the coenzyme form of vitamin B-3, niacin, that carries hydrogen to the production site of ATP.) If this alone was all that MEGA H-™ could accomplish, it would be the most significant nutritional compound yet discovered. But its properties go far beyond energy generation. It is the body’s most efficient and effective antioxidant. MEGA H-™ also increases cellular hydration and the uptake of nutrients into each cell by lowering the surface tension of water (making water “wetter”). And it can improve athletic performance by lowering lactic acid levels after strenuous workouts.
Aging and Antioxidant Defense
Energy Decline: As we age, there is a decrease in our bodies’ ability to generate cellular energy—and oxidative damage may be a primary factor. Many scientists now accept the theory of aging first proposed by noted scientist Denham Harman, M.D., Ph.D., who argued that “aging changes are induced by free radical reactions, largely initiated by the mitochondria … the rate of damage to the mitochondria determines our life span.” Why is this? While oxygen is necessary for human life, the very act of breathing generates free radicals. Our mitochondria— tiny energy production plants—are the chief source of oxidants produced in our bodies. It is believed these oxidants damage the mitochondria in which they are produced, including the inner mitochondrial membrane, which is the site of ATP production. This would seriously impair the ability of mitochondria to meet cellular energy demands. The result: signs of normal aging such as impaired memory, hearing, vision and stamina.
DNA Damage: Oxidants also can damage the cell’s DNA. Hydroxyl radicals cause DNA strands to break; if breaks occur in both strands of DNA, the cell cannot repair the damage and will die. Normally, the body has mechanisms to correct or remove damaged cells. However, as we age and cellular energy production declines, the ability to correct these errors is significantly reduced. Left unrepaired, DNA errors may be passed on when cells divide. Over time, these errors can silently accumulate, leading to cellular changes that go unnoticed until body system imbalances become evident.
World’s Most Elemental Antioxidant
MEGA H-™ may be the world’s most powerful antioxidant. It is possible to measure the Oxidation Reduction Potential (ORP) of any compound. This rating, which measures the number of electrons present in relation to protons, ranges from (plus) +1,200 to (minus) -800 millivolts; the stronger an antioxidant is, the Closer its ORP would be to -800. The more positive the ORP reading, the fewer the number of available electrons from active hydrogen. In chemistry, active hydrogen is defined as hydrogen with an extra electron, also known as the hydrogen anion, negative hydrogen or H-. The strongest natural antioxidants up until now, such as grape seed and green tea, have ORP’s of -100. But Mega H-™ has an ORP of -778 millivolts, as compared to distilled water, making it the most potent natural antioxidant available today. What’s more, MEGA H-™ is in a class by itself, compared to other antioxidants, due to its electrochemical structure. Free radi-cals—unstable molecules that are missing one or more electrons—damage cells by taking electrons from healthy molecules to balance themselves. When other antioxidants donate electrons to quench free radicals, they in turn become reactive free radicals and require electrons from other antioxidants to become stable. The new antioxidant also requires an electron to return to stability. This process continues, resulting in an inefficient and energy-consuming free radical cascade. But MEGA H-™’s negatively charged hydrogen molecule possesses two electrons instead of the typical one. This extra electron can be donated without generating the inefficient free radical cascade. Dr. Flanagan’s profound contribution was his discovery of a method for stabilizing and delivering negatively charged hydrogen (H-). Unlike taking other antioxidants, supplementing with MEGA H-™ provides a net gain of free radical-quenching electrons into the system.
Additional Health Benefits
MEGA H-™ has been the subject of additional positive research: Increases Cellular Hydration: Water is important to cells, interstitial fluids (surrounding joints, muscles and organs), and the matrix of blood. As the body’s primary fluid, water serves as a solvent for nutrients. Since water is used to carry nutrients into the cell, it is theorized that increased cellular hydration also increases the bioavailability of nutrients. Water also eliminates toxins and waste products from the body. From energy production to joint lubrication, all our systems depend on water. It has been theorized that aging results in cell dehydration. A study done by Gary Osborn and H. Salinas, M.D. of the Texas Institute of Functional Medicines suggests that silica hydride supplements like MEGA H-™ increase intracellular, extracellular and total body water levels. It is theorized they work by decreasing water’s surface tension, which allows water and nutrients to more easily enter cells and become available for use by the body. Assists In Exercise Recovery: During strenuous exercise, the oxygen supply to muscle cells is insufficient to meet energy demands. Muscle cells then turn to anaerobic respiration to continue to generate energy. This creates lactic acid, which diffuses into the blood, causing muscle fatigue, soreness and loss of endurance. A placebo-controlled study on six healthy males showed that blood lactate levels significantly decreased after exercise when silica hydride supplements were taken for one week before an exercise trial.
The Scientist Behind Mega H-™
This revolutionary approach to nutrition and health is the brain child of Dr. Patrick Flanagan. Dr. Flanagan was a child prodigy with an intense interest in electronics, biochemistry and physics. At the age of 12, he invented a guided missile and atom bomb detector. This technology was subsequently adopted for use by the U.S. government. At 14 he developed the Neurophone®. This device transmits acoustic information to the brain by means of radio waves into the skin, bypassing the eighth cranial nerve, and may allow some deaf people to hear. By the age of 18, he was named one of the Top Ten most promising young scientists in America by Life Magazine. Dr. Flanagan’s work with MEGA H-™ has its roots in his collaboration with Dr. Henri Coanda, a respected scientist who died in 1972. Dr. Coanda passed along his investigation into Hunza water to Dr. Flanagan. MEGA H- is the culmination of decades of research to bring the energizing and anti-aging benefits of active hydrogen (H-) to the world.
Hydrogen (H-)The Fuel of Life
MEGA H-™ is the first supplement available in the natural foods industry to provide a large reservoir of freely available electrons to power the body’s diverse energy functions.
Under-Reported (and Underappreciated) Cholesterol control.
May 12, 2005 10:00 AM
Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Controlby Richard Conant, L.Ac., C.N.
Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat.
The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol.
Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid.
The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.)
Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them.
Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established.
How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a Closer look.
In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides.
Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels."
Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions.
Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state.
Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves.
Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6
Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels.
When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long.
There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12
We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health.
Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger.
The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E."
It would be a tremendous service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E.
1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.
2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18.
3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.
4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.
5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.
6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86.
7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980.
8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45.
9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93.
10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26.
11. Welsh, A.L. Ede, M. Inositol hexanicotinate for improved nicotinic acid therapy. International Record of Food Medicine 1961;174(1):9-15.
12. "Inositol hexaniacinate" (Monograph). Alternative Medicine Review 1998;3(3):222-3.
13. Serbinova, E., et. al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha tocotrienol. Free Radical Biology and Medicine 1991;10:263-275.
14. Qureshi, N. Qureshi, A.A. Tocotrienols: Novel Hypercholesterolemic Agents with Antioxidant Properties. in 'Vitamin E in Health and Disease' Lester Packer and Jürgen Fuchs, Editors. 1993; New York: Marcel Dekker, Inc.
Control Cholesterol with the following Supplements