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  Messages 1-50 from 85 matching the search criteria.
Argan Oil Benefits Darrell Miller 5/28/19
CoQ10 can help to stop nonalcoholic fatty liver disease, studyreveals Darrell Miller 4/29/19
Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ... Darrell Miller 4/22/19
High levels of CoQ10 can lower your chances of dementia by 77% Darrell Miller 2/8/19
Co-Q10 Could Have Significant Inflammatory Lowering Effects Darrell Miller 5/30/17
Fats, CoQ10 & Antioxidants for Heart Health Darrell Miller 4/7/17
CoQ10 — A Nutritional Powerhouse for Mitochondrial Health Darrell Miller 12/27/16
What Are The Benefits Of Ubiquinol Vs Regular CoQ10? Darrell Miller 5/31/14
How Coenzyme Q10 or CoQ10 cure Cardiovascular? Darrell Miller 5/30/14
Boost Energy With CoQ10 And L-Carnitine Darrell Miller 11/21/13
Does Ubiquinol Get Absorbed Better Than Regular CoQ10 Darrell Miller 11/6/13
What Is Ubiquinol? Darrell Miller 8/23/13
CoQ10: What You Ought to Know about This Substance? Darrell Miller 3/26/13
Coq10 and its benefits Darrell Miller 10/26/12
The Benefits of the Amazing Duo of CoQ10 and Red Yeast Rice Darrell Miller 3/11/12
What Makes Ubiquinol The Best Form Of COQ10? Darrell Miller 3/8/12
What Makes CoQ10 So Good For Your Health? Darrell Miller 2/14/12
Free Radicals And Cancer, How Do I Combat Free Radicals? Darrell Miller 10/12/11
Natural Vitamins for the Heart Darrell Miller 7/6/10
Omega Red And Cholesterol Darrell Miller 8/28/09
Boost Memory Darrell Miller 3/23/09
Ubiquinol Reduced CoQ10 Darrell Miller 4/7/08
Seniors Need More Than a Multiple with Only 100 Percent of the RDA Darrell Miller 1/21/08
Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver Darrell Miller 12/18/07
Kaneka QH - Ubiquinol Darrell Miller 11/30/07
Reduce Your Cholesterol With Natural Vitamins Darrell Miller 7/12/07
Active Coenzyme Q10 Darrell Miller 7/7/07
The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium Darrell Miller 5/18/07
CoQ10 for Heart Health Darrell Miller 3/28/07
Regulating Blood Pressure Naturally Darrell Miller 3/28/07
How does Sytrinol work? Darrell Miller 2/27/07
Neurological Health and CoQ10 Darrell Miller 2/25/07
For Better Heart Health ... Darrell Miller 2/6/07
Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more. Darrell Miller 11/9/06
Lower Cholesterol Naturally! Darrell Miller 10/6/06
What are you really Getting? Darrell Miller 8/21/06
HDL Booster - Boost your good cholesterol Darrell Miller 3/16/06
Ola Loa Multi-Vitamin Mineral Formula Darrell Miller 2/22/06
High Absorption CoQ10 Darrell Miller 2/13/06
Molecularly Distilled Omega-3 fish Oil Fact Sheet Darrell Miller 1/12/06
Effer-C NUTRITION YOU CAN DRINK Darrell Miller 12/27/05
Your Cells Supercharge Your Cells Darrell Miller 12/20/05
GliSODin Anti-Aging and Antioxidant Protection Darrell Miller 12/19/05
The Free Radical Theory Darrell Miller 12/14/05
Coenzyme Q10 and Cardiovascular Health. Darrell Miller 12/13/05
Tru-E Bio Complex Darrell Miller 12/8/05
Co-Enzyme B-Complex Fact Sheet Darrell Miller 12/8/05
Carnitine Creatinate Darrell Miller 12/8/05
Skin Eternal #1 Skin Care Line – Source Naturals Darrell Miller 11/4/05
ENADA® NADH 5mg - NEW PRODUCT ANNOUNCEMENT Darrell Miller 8/3/05



GENCEUTICS 24Hr Microactive COQ10 100mg
   60 cap vegi $31.99 34% OFF $ 21.11
OLYMPIAN LABS Alpha Lipoic CoQ10 200mg
   60 caps $35.49 34% OFF $ 23.42
Natures Plus Beyond CoQ10 Ubiquinol 200mg
   30 sg $55.95 20% OFF $ 44.76
Natures Plus Beyond CoQ10 Ubiquinol 200mg
   60 sg $100.90 20% OFF $ 80.72
Kal CoQ10
   30ct 100mg $34.69 45% OFF $ 19.08
NUTRAKEY COQ10
   60 CAPSULES $24.99 28% OFF $ 17.99
Doctors Best CoQ10 + Selenium
   90VC $39.99 43% OFF $ 22.79
Life Time CoQ10 100mg
   30 + 30 Softgel $24.49 34% OFF $ 16.16
Thompson Nutritional CoQ10 100mg
   30 ct $22.19 42% OFF $ 12.87
Now Foods CoQ10 100mg
   150 SOFTGELS $55.99 45% OFF $ 30.79
OLYMPIAN LABS CoQ10 100mg
   60 caps $30.49 34% OFF $ 20.12
OLYMPIAN LABS CoQ10 100mg
   30 softgels $18.99 34% OFF $ 12.53
OLYMPIAN LABS CoQ10 100mg
   90 softgels $45.99 34% OFF $ 30.35
Best Naturals CoQ10 100mg
   120 cap $29.99 29% OFF $ 21.29
NOW FOODS CoQ10 100mg 50 SGELS
   50 SOFTGELS $21.99 23% OFF $ 16.93
NOW FOODS CoQ10 100mg 30 VCAPS
   30 VCAPS $14.99 45% OFF $ 8.24
HEALTHY ORIGINS CoQ10 100mg (Kaneka Q10)
   30 softgel $22.99 35% OFF $ 14.94
HEALTHY ORIGINS CoQ10 100mg (Kaneka Q10)
   60 softgel $39.99 35% OFF $ 25.99
HEALTHY ORIGINS CoQ10 100mg (Kaneka Q10)
   150 softgel $86.99 35% OFF $ 56.54
NOW FOODS CoQ10 100mg 180 VCAPS
   180 vcaps $61.99 45% OFF $ 34.09
NOW FOODS CoQ10 100mg 90 VCAPS
   90 VCAPS $35.99 45% OFF $ 19.79
NATROL CoQ10 100mg Bonus Size
   45 caps $23.19 34% OFF $ 15.31
NATROL CoQ10 100mg Fast Dissolve
   30 TAB $14.99 29% OFF $ 10.64
Best Naturals CoQ10 120 mg
   120 cap $35.99 29% OFF $ 25.55
Life Time CoQ10 120mg
   30 Softgel $21.99 34% OFF $ 14.51
Life Time CoQ10 120mg
   30+30 softgel $29.31 34% OFF $ 19.34
OLYMPIAN LABS CoQ10 150mg
   60 caps $35.99 34% OFF $ 23.75
NOW FOODS CoQ10 150mg 100 VCAPS
   100 VCAPS $47.99 45% OFF $ 26.39
Best Naturals CoQ10 200 mg
   120 cap $54.99 29% OFF $ 39.04
Solaray CoQ10 200mg
   30ct Vegetarian Capsule $47.19 45% OFF $ 25.95
NATROL CoQ10 200mg
   45 softgels $31.99 35% OFF $ 20.79
NOW FOODS CoQ10 200mg & VIT E 90 LOZ
   90 LOZ $53.99 45% OFF $ 29.69
HEALTHY ORIGINS CoQ10 200mg (Kaneka Q10)
   30 softgel $37.99 35% OFF $ 24.69
HEALTHY ORIGINS CoQ10 200mg (Kaneka Q10)
   60 softgel $67.99 35% OFF $ 44.19
HEALTHY ORIGINS CoQ10 200mg (Kaneka Q10)
   150 softgel $147.99 35% OFF $ 96.19
NOW FOODS CoQ10 200mg Vegetarian
   60 VCaps $39.99 45% OFF $ 21.99
OLYMPIAN LABS CoQ10 300mg
   60 cap vegi $60.99 37% OFF $ 38.42
HEALTHY ORIGINS CoQ10 300mg (Kaneka Q10)
   60 softgel $89.99 35% OFF $ 58.49
Life Time CoQ10 30mg
   30 Softgel $9.89 34% OFF $ 6.53
Life Time CoQ10 30mg
   30+30 softgel $13.18 34% OFF $ 8.70
NOW FOODS CoQ10 30mg 120 VCAPS
   120 VCAPS $18.99 45% OFF $ 10.44
NOW FOODS CoQ10 30mg 240 VCAPS
   240 VCAPS $35.99 45% OFF $ 19.79
NOW FOODS CoQ10 30mg 60 VCAPS
   60 VCAPS $9.99 45% OFF $ 5.49
Best Naturals CoQ10 400 mg
   60 cap $69.99 29% OFF $ 49.69
Life Time CoQ10 400mg
   30 Softgel $47.59 34% OFF $ 31.41
NOW FOODS CoQ10 400mg 30 SGELS
   30 SOFTGELS $39.99 45% OFF $ 21.99
NOW FOODS CoQ10 400mg 60 SGELS
   60 SOFTGELS $69.99 45% OFF $ 38.49
HEALTHY ORIGINS CoQ10 400mg (Kaneka Q10)
   60 softgel $109.99 35% OFF $ 71.49
NOW FOODS CoQ10 50mg + VIT E 200 SGELS
   200 SOFTGELS $53.99 45% OFF $ 29.69
NOW FOODS CoQ10 50mg + VIT E 100 SGELS
   100 SOFTGELS $29.99 23% OFF $ 23.09

Argan Oil Benefits
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Date: May 28, 2019 11:07 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Argan Oil Benefits





Moroccans have been using argan oil for centuries because it has a good, nufty flavor but also many health benefits. This has made the oil, derived from the fruit of the argan tree, very popular worldwide although it is native to Morocco. It is widely known and used for culinary, cosmetic, and medicinal purposes. The author suggests some 12 uses of argan oil in the blog. One of the uses is that it contains essential nutrients which are usually fatty acids like oleic and linoleic acid. These fatty acids are good sources for the health and also it contains a rich source of vitamin E. Another usefulness of argan oil is that is has antioxidant and anti-inflammatory properties. Some of its compounds that make this possible are vitamin E, CoQ10, melatonin, and plant sterols. The author states that more research is needed though to fully understand how argan oil is antioxidant and anti-inflammatory. Another good reason to use argan oil is that it boosts heart health. This is due to the omega-9 fatty acid, oleic acid, it contains. Other reasons to use argan oil are found in the blog.

Key Takeaways:

  • Argan oil has been used in Moroccan cooking for centuries because of its flavor and health benefits.
  • Argan oil is a healthy fat that is good for the hair, skin, and eyes.
  • Because argan oil is high in anti-oxidants, it has promising benefits for heart health and diabetes.

"Although native to Morocco, argan oil is now used across the globe for a variety of culinary, cosmetic and medicinal applications."

Read more: https://www.ecowatch.com/argan-oil-2634443123.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6340)


CoQ10 can help to stop nonalcoholic fatty liver disease, studyreveals
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Date: April 29, 2019 05:04 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CoQ10 can help to stop nonalcoholic fatty liver disease, studyreveals





Fatty liver disease is something that many people struggle with and fear in their lifetimes. Because it is nonalcoholic, it is difficult to rationalize having the disease as it is not intentionally done. Many professionals have attempted to lessen the ability to get the disease, and there is a medication that helps to put a stop to the disease. The medicine is called CoQ10 and it is very effective at halting inflammation in and around the liver.

Key Takeaways:

  • One powerful antioxidant that the body produces naturally is CoQ10 and the problem is that it gets depeleted thereby contributing to liver disease.
  • CoQ10 has been shown to reverse the effects of nonalchoholic fatty liver disease (NAFLD) which is due to the accumulation of fats in the liver.
  • Nonalcholic fatty liver disease (NAFLD) is a big problem in America because 30 percent of adult Americans have it and they have no idea it’s happening to them.

"Those receiving the CoQ10 supplement showed better markers overall after the study period was completed as compared with the placebo group."

Read more: https://www.naturalhealth365.com/fatty-liver-disease-coq10-2789.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6217)


Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ...
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Date: April 22, 2019 04:29 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ...





Many Coenzyme Q10 products have labels that indicate that their product is better absorbed due to longtime beliefs surrounding ubiquinol (reduced Coenzyme Q10) being hard for the body to absorb. Many brands instead market ubiquinone, which is redox Coenzyme Q10 instead, since studies have been more supportive about this form being easier for the body to absorb. New research, however, is concluding that both of these forms are equal when it comes to the ability to be absorbed through the body.

Key Takeaways:

  • According to Coenzyme Q10 expert Dr. William Judy, there is very little difference in the absorption rates of ubiquinol and ubiquinone.
  • Both forms of CoQ10 contain antioxidants and are critical for overall mitochondrial health.
  • CoQ10 can be beneficial for those suffering from Parkinson's disease and has been shown to provide headache relief in adolescent and pediatric populations.

"Marketing terms such as “better absorbed” should be questioned unless the absorption or bioavailability is actually stated. Only when the actual absorption has been verified can the better absorbed product be determined."

Read more: https://wholefoodsmagazine.com/columns/vitamin-connection/coenzyme-q10-research-confirms-ubiquinone-and-ubiquinol-are-nearly-equally-absorbed-compounds-the-physical-form-and-companion-ingredients-make-the-bioavailability-and-absorption-difference-in-coenz/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6152)


High levels of CoQ10 can lower your chances of dementia by 77%
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Date: February 08, 2019 08:30 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: High levels of CoQ10 can lower your chances of dementia by 77%





There is now even more reason to ensure that you're taking a CoQ10 supplment. New evidence suggests that it can lower your risks of developing dementia by 77% or more! This is in addition to the many amazing health benefits this substance is already known to offer. If you want to live the best life being the healthiest you that you can live, it is worth adding CoQ10 supplement to your diet sooner instead of later!

Key Takeaways:

  • The fight against dementia is ongoing. Foods like berries are known to reduce risk to it but more exciting is the discovery that Coenzyme Q10 can reduce your risk.
  • The study involved measuring the serum CoQ10 levels of older persons aged between 40 and 69. They measured these levels for those who had dementia and those who didn’t.
  • Their discovery was that people with high levels of CoQ10 were safer from dementia. The top 25 percent has a 77 percent lower chance of having dementia.

"Dementia, despite its prevalence, remains largely a mystery to doctors and scientists, who have yet to find a foolproof way to prevent or treat the illness."

Read more: https://www.naturalnews.com/2018-12-22-high-levels-of-coq10-can-lower-your-chances-of-dementia.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6010)


Co-Q10 Could Have Significant Inflammatory Lowering Effects
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Date: May 30, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Co-Q10 Could Have Significant Inflammatory Lowering Effects





A website owned by a health supplement company has reproduced a summary of a report published in a medical journal about the enzyme Co-Q10. The summary tested the enzyme on some indicators of inflammation. It concluded that Co-Q10 did reduce inflammation. The website noted in a foreword that some physicians have recommended using Co-Q10 to treat Lyme disease symptoms. website posted the source of the summary, including an embedded link for the full study. Ten people shared the website story.

Key Takeaways:

  • The purpose of this study was to evaluate the effects of CoQ10 by analyzing published randomized controlled trials.
  • CoQ10 had greater effects on subjects with a higher baseline IL-6 levels.
  • study concluded that CoQ10 signifigantly lowered CRP, IL-6, & TNF.

"results should be interpreted with caution because of the evidence of heterogeneity and limited number of studies"

Read more: http://www.prohealth.com/library/showarticle.cfm?libid=30257

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4729)


Fats, CoQ10 & Antioxidants for Heart Health
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Date: April 07, 2017 10:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Fats, CoQ10 & Antioxidants for Heart Health





Heart disease is the leading cause of death in the U.S. and is not just a disease the effects the elderly. While nutrition and exercise is important, so are cholesterol levels. Good cholesterol is needed in the body. Natural fats, like omega 3 and Vitamin C, are better than trans fats for the body. Keeping antioxidants healthy is also a major part of keeping the heart healthy. By understanding and implementing some of these techniques, people can lower the risk of heart disease.

Read more: Fats, CoQ10 & Antioxidants for Heart Health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4369)


CoQ10 — A Nutritional Powerhouse for Mitochondrial Health
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Date: December 27, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CoQ10 — A Nutritional Powerhouse for Mitochondrial Health





coenzyme Q10, which is referred to as CoQ10 is gaining popularity in the supplement marketplace. The number of Americans who are using this supplement has risen to twenty-four million people. This is good news as research shows its benefits. New research shows it keeps the mitochondria healthy, allowing for oxygen to be converted to energy.

Key Takeaways:

  • At present, at least 1 in 4 American adults over the age of 40 are taking a statin — ostensibly to protect their heart health.
  • This is the enzyme inhibited by statin drugs. This means that, in addition to lowering your cholesterol, the drug also compromises your body's ability to benefit from a healthy and cleaner-burning fuel (fat).
  • Recent research found that taking CoQ10 in combination with selenium improves heart function and cuts cardiovascular mortality by nearly 50 percent in elderly people.

"Between 2000 and 2016, the number of Americans using CoQ10 increased from an estimated 2 million to 24 million, and the number of brands featuring CoQ10 has increased from 18 brands to 125."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.prohealth.com/library/showarticle.cfm%3Flibid%3D29771&ct=ga&cd=CAIyGjVkYjY3ZDViNDdiNGM3ZTc6Y29tOmVuOlVT&usg=AFQjCNFStHXdUv1oYIMpcXavYYI0sc130w

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3707)


What Are The Benefits Of Ubiquinol Vs Regular CoQ10?
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Date: May 31, 2014 06:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Benefits Of Ubiquinol Vs Regular CoQ10?

fruits and vegetables Nutritional Supplement

In modern society, nutritional supplements have become a common method to improve health. A wide range of specific needs determines the use of different supplements, but there are a few that will work in just about everyone and improve their health.

What is a CoQ10

Coenzyme Q10, commonly abbreviated to CoQ10, is one of those universally effective supplements. This vitamin-like substance offers far-reaching benefits for the human body. It has a crucial role in the body's energy maintenance and it's an extremely powerful antioxidant. This substance is naturally produced by the body, but as we get older, the organism's ability to synthesize CoQ10 weakens progressively. It is, therefore, recommended that people initiate a regular intake of CoQ10 somewhere at the adult or even young adult life stage. This is a commonly prescribed supplement for old people owing to its longevity and energy inducing benefits, but it's especially critical for those who are medicated with statin drugs because these are known to reduce CoQ10 levels in the organism. Elite athletes can also benefit from this substance to achieve higher peak power levels.

CoQ10 supplement is available in two forms: fully oxidized (Ubiquinone) and fully reduced (Ubiquinol).

What is an Ubiquinol

Ubiquinol is the most efficient way to take advantage of this supplement because it's the fully reduced form of CoQ10 that our body actually absorbs and uses. The consumption of Ubiquinone requires our body to firstly metabolize and convert it into Ubiquinol. This process limits the speed and efficiency of CoQ10 absorption, requiring larger quantities to be consumed for similar health effects, not to mention that the metabolism has a tendency to worsen with age. Ubiquinone is more widely available and is cheaper, though.

It is usually recommended for people around the age of 35 - 40, to start taking Ubiquinol instead of Ubiquinone. This is when the efficiency of Ubiquinol eventually compensates its higher price tag over Ubiquinone. Turning the ingestion of CoQ10 supplement into a habit is one of the best ways to potentiate a long and healthy life.

Sources:

  1. en.wikipedia.org/wiki/Ubiquinol
  2. en.wikipedia.org/wiki/Coenzyme_Q10#Biosynthesis
  3. articles.mercola.com/sites/articles/archive/2013/11/03/CoQ10-vs-ubiquinol.aspx
  4. www.bodybuilding.com/fun/CoQ10-ubiquinone-ubiquinol-whats-the-difference.htm
  5. www.ncbi.nlm.nih.gov/pmc/articles/PMC3661336/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3129)


How Coenzyme Q10 or CoQ10 cure Cardiovascular?
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Date: May 30, 2014 08:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Coenzyme Q10 or CoQ10 cure Cardiovascular?

CoQ10What is a CoQ10

Coenzyme Q10 is shortly known as CoQ10. Coenzyme Q10 is a type of antioxidant, which is made in the human body. Actually, Coenzyme Q10 or CoQ10 is such an element like a vitamin. This component was first found in 1957. Undoubtedly, it performs a vital role to generate necessary energy in cells. It also helps the human body from damaging of cells.

Benefits of CoQ10

CoQ10 is great stuff as a dietary supplementary. It also helps a lot to treat the Cardiovascular Disease. Undoubtedly, it is a perfect remedy for the heart diseases. It is such a component, which enhances the athletic abilities. It also contributes to slow aging.

According to a survey, CoQ10 reduces the systolic pressure about 11 to 18 points and meanwhile 8 to 10 points for the diastolic pressure. The people whose have critical heart disease; they possess a lower amount of Coenzyme Q10. The cells of the heart are very sensitive, but Coenzyme Q10 can handle the heart diseases comfortably. Another survey showed us that, the death rates of those, whose are affected by heart disease and have a low amount of Coenzyme Q10 is increased. Actually, Coenzyme Q10 benefits the total cardiovascular system for the health. Its antioxidant helps a lot to benefit the cardiovascular system. Actually, these are not enough to recommend CoQ10 for cardiovascular. It has already performed a great performance on the cardiovascular system. A recent review has showed us that CoQ10 gradually reduces the death rates among the heart disease's patient. However, it has some negative impact on Diabetes, Hepatitis C but it is the top most dependable component of the heart disease or improving cardiovascular to be honest. Therefore, it proves that it is side effect free for your heart and no doubt you can count on it.

 

Sources

  1. //www.berkeleywellness. com/ supplements/ other-supplements/article/can-you-count-coenzyme-q10
  2. //en.wikipedia. org/wiki/ Cardiovascular_disease
  3. //www.mayoclinic. org/ drugs-supplements/coenzyme-q10/background/ hrb-20059019
  4. //www.webmd. com/ heart-disease/heart-failure/tc/ coenzyme-q10-topic-overview

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Boost Energy With CoQ10 And L-Carnitine
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Date: November 21, 2013 08:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Energy With CoQ10 And L-Carnitine

CoQ10 and L-Carnatine

 L-CarnatineCoQ10 and L-Carnitine offer double protection for the heart and the brain in just a single tablet. You obtain all benefits for your heart at 100% from CoQ10, while L-Carnitine supports your memory, learning ability, and focus. The exclusive combination of CoenzymeQ10 and L-Carnitine encloses an absorbable, water soluble capsule of CoQ10 and L-Carnitine, which is important for proper usage.

Why are CoQ10 and L-Carnitine Supportive in Energy Boost?

CoQ10 Energy Boost

CoQ10 is a vital nutritional element found in all body cells, in particular the mitochondria, in which most energy is generated. The major function of this coenzyme is to assist in the process of oxygen and food conversion into energy. As people grow older their ability to naturally, to produce this coenzyme decays.

At the same time as Coenzyme Q10 is taking part in the production of energy in each cell of your body, it is considered be remarkably imperative for the high energy requirements of the heart. The heart needs vast energy amounts, because it is the hardest worker in your entire body. Coenzyme Q10 seems to be indispensable for this process. It offers you sufficient antioxidant provision, protecting the body cells from damage of the free radicals, and proffering a dynamic function of the immune system.

L-Carnitine Energy Boost

L-Carnitine transports indispensable fat acids into the same organ where CoQ10 plays its major function - the mitochondria. There, with the help of L-Carnitine, all fatty acids are turned into energy. However, the beneficial function of L-Carnitine does not end here. In addition, it also supports the transportation of toxins outside the body. You can think of the problems that might occur if these vital body processes are not fully operational. At the same time however, the major impact of L-Carnitine over the body is directed towards the brain:
  • Cognitive function and concentration support
  • Cell membrane health support
  • Improves clarity and happiness
Encouraging the overall health of your brain, while offering your heart supreme support, the combination of CoQ10 and L-Carnitine is the best solution for you, in terms of:
  • Supporting your heart's energy needs
  • Providing essential nutrition for all cells of the body
  • Delivering powerful antioxidants, which protect your body
References:
  1. //www.webmd.com/heart-disease/heart-failure/tc/coenzyme-q10-topic-overview
  2. //www.webmd.com/vitamins-supplements/ingredientmono-1026-L-CARNITINE.aspx?activeIngredientId=1026&activeIngredientName=L-CARNITINE
  3. //www.poliquingroup.com/ArticlesMultimedia/Articles/Article/767/Top_12_Reasons_to_Use_Carnitine.aspx
  4. //nutritionalengineering.org/CoQ10-acetyl-l-carnitine-supplement.htm
  5. //www.livestrong.com/article/489829-why-should-i-take-l-carnitine-with-CoQ10/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2900)


Does Ubiquinol Get Absorbed Better Than Regular CoQ10
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Date: November 06, 2013 08:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Ubiquinol Get Absorbed Better Than Regular CoQ10

 Benefits is Ubiquinol

Ubiquinol can be described as reduced form of CoQ10 (Ubiquinone). For an individual to benefit from the type of nutrient that is needed for producing cellular energy and reduce signs of aging, the body has to convert ubiquinone to ubiquinol. Studies have shown that it gets absorbed better than CoQ10. It is also known to reduce exercise induced fatigue by around 90% when compared with Ubiquinone. This is probably because CoQ10 has a chemical nature that undergoes “redox chemistry”. This implies that it flips back and forth between not having and having two additional electrons.

Importance of Ubiquinol to Human Body

This is a very important part of the human body because it transports flow of electrons that permits chemical energy to be harnessed down a gradient. This is normally the last stage where food is converted to energy to fuel the body. Ubiquinol on the other hand is the form where these extra electrons are reduced when speaking in chemistry terms. Although there is a small difference between the two, it really has big implications as this is exactly what makes it to be more absorbable in the intestines. In addition to this, the body prefers this form to perform the transport function of the blood. 

It is important to note that Ubiquinol was introduced to the market when Kaneka discovered techniques on how to stabilize the ingredient in 2006. From then, it has become an ingredient in numerous products. Various findings also show that it is the preferred form when it comes to ingestion. There are some studies that also show that this form is beneficial for patients who are suffering from advanced stage cardiac disorders. This is because it is absorbed much easily and also shows potential for greater clinical benefit. Manufactures are also looking into new and more advanced methods that will be used to make sure that it can be absorbed more easily than before.

References:

  1. //www.naturalproductsinsider.com/articles/2013/03/CoQ10-vs-ubiquinol.aspx
  2. //www.lef.org/magazine/mag2007/ss2007_report_CoQ10_01.htm
  3. //products.mercola.com/CoQ10-ubiquinol/

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What Is Ubiquinol?
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Date: August 23, 2013 02:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Ubiquinol?

Coenzyme Q10 (Co10) is a naturally-occurring chemical compound in the body which fuels cell growth and enhances enzyme functions. It exists in three forms; ubiquinone (fully oxidized), semiquinone (partially reduced), and ubiquinol (fully reduced). So, ubiquinol is basically a reduced form of Co10, it is a strong antioxidant that can neutralize free radicals. Free radicals refer to a reactive and unstable atom that can trigger many medical conditions such as cardiovascular issues, weak immunity and even cancer.

Ubiquinol is found in almost every organ, tissue and cell in mammals. This lipid-soluble benzoquinol can be acquired through supplementation, biosynthesis and from diet (in small amounts). Ubiquinol plays an integral role in transferring electrons within the body, thereby leading to ATP synthesis. The antioxidant property of ubiquinol is very essential in the functioning of the cellular systems.

Ubiquinone is naturally converted into ubiquinol by the body to produce energy for the cells. The failure of this process can lead to insufficient energy levels in the body. The ability of the body to generate Coenzyme Q10 reduces with age and so does the ability to convert ubiquinone into ubiquinol. Therefore, older people should use ubiquinol supplements to boost their energy levels. Apart from older people, those who suffer from neurological, cardiovascular, diabetes and liver conditions may also have low ubiquinol levels.

There are many health benefits associated with ubiquinol. First, it offers a sufficient amount of energy which the heart needs to work well. It's also a strong antioxidant that protects the heart, and other vital body organs from free radicals. When it comes to energy, ubiquinol is an essential component in 95 percent of the energy produced in the body. Daily intake of ubiquinol supplement can help reduce fatigue and muscle pains; the common symptoms of insufficient Coenzyme Q10 in the body. Since ubiquinol is a strong fat soluble antioxidant, it can protect the body from oxidation, thereby providing an anti-aging benefit.

Do you feel fatigued, run down with no energy?  Consider Ubiquinol as a natural safe energy boosting supplement.

References

  1. //en.wikipedia.org/wiki/Ubiquinol
  2. //products.mercola.com/CoQ10-ubiquinol/
  3. //www.kanekaqh.com/benefits-of-ubiquinol.html

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CoQ10: What You Ought to Know about This Substance?
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Date: March 26, 2013 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10: What You Ought to Know about This Substance?

Coenzyme Q10 or simply CoQ10 is a substance naturally present not only in a human's body but as well as with the other mammals. It plays a vital role in the production of energy. Back in the year 1957, Dr. Frederick Crane successfully used the mitochondria from the cells of a beef heart in order to locate Coenzyme Q10. But the truth of the matter is that, the substance is also present in human mitochondria. Basically, this substance has antioxidant properties which are highly beneficial in protecting the body against the free radicals present in the environment. Below are some relevant details you ought to know about this substance.

Here they are:

CoQ10 in Kreb's Cycle

There are a number of chemicals that the body needs to induce metabolism and one of those chemicals is CoQ10. The Kerb's Cycle is the body's mechanism to convert certain enzymes into energy. In order to achieve that, the body needs CoQ10 to facilitate the conversion of the enzymes in energy production. CoQ10 is fundamental in the Kerb's Cycle as it supports the electron transport chain in which the oxidative phosphorylation of the ADP (adenosine diphosphate) into ATP (andenosine triphosphate) needs electrons that are exactly delivered where they must be. Without CoQ10, the entire Kerb's Cycle process would certainly fail. The mitochondria of every power cells synthesize CoQ10 so the substance is present in almost all the body parts. However, the heart consumes the most CoQ10 for the reason that it has the most number of mitochondria and it keeps on working even while the body is at rest.

CoQ10 Deficiency

If the Kerb's Cycle fails due to CoQ10 deficiency, the person will feel exhausted and weak. But aside from that, there are other conditions that are often associated with the deficiency such as cardiovascular related diseases, Parkinson's disease and gum disease. Conversely, it doesn't necessarily mean that those diseases are brought about by CoQ10 deficiency.

CoQ10 Dietary Sources

The main sources of CoQ10 include fish oil, whole grains and organ meats. With a balance diet, people can get sufficient amount of coenzyme Q10.

CoQ10 Supplements

Aging is an inevitable process and it can affect the synthesis of CoQ10. As humans grow older, the production of the coenzyme Q10 gradually decreases. It was mentioned earlier some of the foods that are incredibly beneficial in maintaining ample amount of CoQ10 in the body. But people who do not really include those foods in their diet should not worry for there are now food supplements that contain CoQ10.  Some medications like cholesterol meds can prevent the body from using CoQ10, this is when it is essential for one to take a supplement.

Fortunately, with the advent of medical researches and innovative technology in drug manufacturing, CoQ10 can now be ingested into one single tablet, soft gel capsule, hard shell capsule or an oral spray. CoQ10 is a fat-soluble substance so taking it along with foods is highly encouraged.

Who Takes CoQ10 Supplement?

Children under 18 years old are not allowed to take CoQ10 supplements unless prescribed by the doctor. For adults at the age of 19 or older, the recommended dosage in 30 - 600 mg daily. Higher dosage may be taken for special conditions.

Humans need energy in order to carry out all the tasks. Therefore, CoQ10 must be taken daily, whether from foods or supplements, so the body has the energy to move.

Have you had your CoQ10 Today?

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Coq10 and its benefits
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Date: October 26, 2012 11:04 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10 and its benefits

CoQ10

We insist that vitamins and essential nutrients should be an essential part of our daily diet. But are we aware that some vitamins and chemical nutrients are also created naturally in our bodies? One such essential compound is known as CoQ10. Found in most living organisms, CoQ10 also known, as ubiquinone is a chemical that boosts the levels of energy produced in the body. It monitors the functioning of the mitochondria and cells that are useful for metabolizing the fat in the body. Without the presence of this essential compound, there could be some serious problems. Here are its respective virtues for people.

Heart And Muscle Repair

Scientific studies have proved that the enhanced production ofCoQ10 has helped to solve some major health issues for people. The enhanced production of the compound was instrumental in strengthening the muscles and tissues of the heart. This meant that adequate levels of CoQ10 help to reduce the congestion in the heart and veins. Also, the presence of this ubiquitous compound will also help in getting respite from muscular dystrophy. Also, those, who are vulnerable to breathing problems and arrhythmia, can also find a solution through such a compound in their bodies.

Immunity And Blood Pressure

Those, who have the problem of high blood pressure, would be advised to eat more of things like fish or meat as these contain CoQ10 in good amounts. Adequate levels of this chemical will aid in reducing the levels of blood pressure and improving the circulation of blood in the body. Also, CoQ10 is known for improving the person's immunity against the common degenerative diseases as well as cancers and malignant tumors and so on. Thus, it can be safely said that CoQ10 is a powerhouse of nutrients that help to keep disastrous afflictions at bay. You should have more of it.

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The Benefits of the Amazing Duo of CoQ10 and Red Yeast Rice
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Date: March 11, 2012 03:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Benefits of the Amazing Duo of CoQ10 and Red Yeast Rice

What Is Cholesterol?

Cholesterol is a substance produced by the liver that provides a number of benefits to the body. A problem occurs when the level of blood LDL or bad cholesterol goes beyond a normal level. High level of bad cholesterol in the body can inflict damage to the arteries during the process of oxidation which can lead to the heavy accumulation of stiffened fats and deposits in the walls of the arteries. This can constrict the arteries that eventually lead to a minimal flow of oxygen-rich blood to the heart and brain. Inadequate supply of blood to the heart and brain can trigger heart attack and stroke. When the kidney perceives an inadequacy in the supply of blood to the brain and heart, it produces substances that help in increasing the supply of blood to these organs. However, in effect, it also increases blood pressure.

Many serious health complications emanate from abnormally high levels of bad cholesterol or low density lipoprotein (LDL) in the body. As people get older, their awareness about maintaining an optimum level of cholesterol should increase significantly. Undeniably, cardiovascular diseases that are triggered by high levels of cholesterol in the body have been one of the major causes of death worldwide.

Red Yeast Rice

Intake of red yeast rice is considered to be one of the most effective alternative ways to lower the level of cholesterol in the body. It is produced by fermenting a certain type of red yeast that is poured over the rice. Researchers believed that red yeast rice contains high levels of substance lovastatin that inhibits the production of enzyme HMG-CoA reductase which is responsible in regulating the production of cholesterol in the body. Red yeast rice actually contains sufficient amount of monacolin K and 8 more monacolin substances that are work like statin drugs in reducing the level of cholesterol. Basically, the substances prevent the liver from producing alarming level of bad cholesterol.

Lowering Effects of LDL

Red yeast rice is a great alternative choice for patients who are searching for non-prescription ways of lowering their cholesterol. A clinical study shows that red yeast rice can significantly lower the level of cholesterol in the body by as much as 20% without exposing the victim to the risk of suffering from muscle pain. Another study reveals that after taking 1800mg of RYR daily for 12 weeks, the users' bad cholesterol level have significantly drop by 27%.

Red yeast rice is actually an FDA-recognized dietary supplement. It is renowned for its capacity to work similar to a statin drug that effectively drives the body to achieve an optimum level of cholesterol. A number of scientific studies revealed that intake of red yeast rice can significantly lower the levels of bad cholesterol and triglycerides in the body. Furthermore, studies show that continuous intake of red yeast rice can contribute a lot in improving the amount of total cholesterol.

Together with red yeast rice, CoQ10 make an amazing duo in lowering the level of bad cholesterol in the body and promote overall cardiovascular health. Intake of CoQ10 is highly recommended to people who take red yeast rice because CoQ10 provides energy and strength to the heart when pumping blood to other organs. When used together, CoQ10 and red yeast rice can increase the transfer of oxygen and energy between the cells and the blood which leads to a significant reduction in the level of cholesterol produced.

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What Makes Ubiquinol The Best Form Of COQ10?
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Date: March 08, 2012 11:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Ubiquinol The Best Form Of CoQ10?

Benefits of Ubiquinol

Ubiquinol is an active antioxidant form of CoQ10. It is pre-converted and ready-to-use diet supplement. Hence, it is easily absorbed and utilized by the body. Research studies show that ubiquinol has proved to be much more effective than ubiquinone and has all vital health benefits as CoQ10.

Ubiquinol is the next generation supplement which provides support for a healthy body and mind. It helps you to live a healthy life by raising your CoQ10 plasma level. It also plays an important role in production of energy levels. Moreover, it protects the cells of the body from oxidative kind of stress which can eventually damage proteins, DNA, and lipids.

Benefits of Ubiquinol:

Cardiovascular health: Clinical studies show that ubiquinol improves the overall cardiovascular health. Cardiac patients who have been taking high dosages of statins like Lipitor, Zocor, etc for a long period of time have decreased levels of coenzyme Q10 as these statins inhibit the body's production level of coenzyme Q10. The low levels of CoQ10 in the body can result in cardiomyalgia, fibromyalgia, atherosclerosis, etc. Thus, if these patients take ubiquinol which is an antioxidant then it neutralizes the oxidation of LDL.

Cognitive Health: It helps to increase the stamina and energy and promotes general health and wellness.

Anti-aging support: Due to degeneration and advanced age, the aged people have less CoQ10 biosynthesis and body's conversion ability also diminishes in such subjects. A collaborated study carried out on middle aged people demonstrated that subjects who were given this supplement showed marked improvement in their physical and mental activities. Thus ubiquinol by and large promotes life extension and improves the overall mental health by compensating for the age-related conversion disability.

Power to other organs: Ubiquinol plays an important role in igniting energy levels within the cells of vital organs like heart, kidneys, liver, and lungs. Thus it naturally helps you to sustain your energy levels.

Protects Cells: Ubiquinol protect cells of vital organ like heart from further damage and from constant attack by free radicals.

Neuronal Health: Ubiquinol benefits the neurological system and promotes brain health. Studies carried out on patients who had Parkinson's disease have proved that it reduces the functional decline in these patients.

Oral Health: Ubiquinol impacts the oral health and significantly enhances the salivary coenzyme Q10 levels. It affects all aspects of mouth, teeth, lips, tongue, and salivary glands.

Renal Health: Studies show that Ubiquinol gives significant renal protection to patients who have chronic kidney disease.

Your body constantly produces powerful antioxidants daily when you are young. But as you age, your body can not sustain this natural production level forever. Hence ubiquinol supplementation is important to promote overall good health. Ubiquinol can be used as a dietary supplement. Its ready-to-use formula is eight times more effective as it can be readily absorbed by your body. Thus it is an ideal diet supplementation for current CoQ10 users.

At present there are no known side effects of ubiquinol, but if you are on multi-drug therapy or are already taking other supplementations, then please consult your doctor prior taking this diet supplementation Ubiquinol.

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What Makes CoQ10 So Good For Your Health?
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Date: February 14, 2012 07:51 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes CoQ10 So Good For Your Health?

BENEFITS OF TAKING C0Q10

C0Q10 is a coenzyme that is produced naturally by the body or supplied by the various foods consumed such as oily fish, whole grains and liver. One of the functions of this chemical compound is to produce adenosine-50- triphosphate in the body cells that contributes to production of energy for the various metabolic and physical purposes. CoQ10 is very important in the body because it helps to maintain and improve the health in the human body. One of the benefits of taking it that it helps to solve obesity, reduce fatigue as well as improve the ability of the body to fight diseases.

Research has proved that the chemical compound helps to prevent accumulation of toxins in the gums that leads to swollen gums. Doctors also indicate that it has the ability to increase fertility through enhanced sperm motility. In the Sport persons it helps to increase and improve their athletic performance through enhanced energy production. However it is important to exercise in moderation to avoid a decline in the levels of this compound due to excessive exercise.

C0Q10 helps to prevent the occurrence of heart diseases in persons. Research shows that the levels of this compound are low in person suffering from heart diseases while persons with high levels of the chemical are less susceptible to heart diseases. Hence taking this health chemical compound daily can help to reduce the chances of one suffering from heart complications. Doctors also use it to treat patients who suffer from congestive heart failure.

High blood pressure is one of the causes of heart problems in most people. C0Q10 helps to lower the blood pressure in the body hence preventing damage of the heart. Before a heart surgery, surgeons introduce the compound into the patient so as to prevent irregular heart beat as well as strengthen heart functioning during the recovery period after the surgery. This is achieved through reduction of damage that may be caused by free radicals and oxidative damage.

Recent research has also shown that CoQ10 in diabetic patients helps to prevent them from experiencing hypoglycaemic response. However patients should consult a doctor before taking the drug so as to get advice on how to take the drugs safely. CoQ10 supplements achieve this through reduction of cholesterol levels in the blood which in turn maintains the level of blood sugar at the recommended level.

Presence of free radicals in the body results in health complications such as fast aging and destruction of the cell membrane. CoQ10 has some antioxidants that eliminate these free radicals from the body. It also prevents the radicals from causing oxidative damage to the DNA in the cells. Accumulation of free radicals in the tissues is usually as a result of certain behaviours such as cigarette smoking, UV light, pollution and also as from the various metabolic processes that take place in the body.

Due to the positive results of CoQ10 in preventing heart problems and maintain the body systems in the body, researchers and scientists hope that the drug can be used to treat Alzheimer disease and breast cancer in women.

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Free Radicals And Cancer, How Do I Combat Free Radicals?
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Date: October 12, 2011 01:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Free Radicals And Cancer, How Do I Combat Free Radicals?

Free Radicals Overview

Free radicals, just the very sound of those words are so dreaded in so many consultation clinics around the country today, this substance has mainly been linked to cancer and its proliferation but what else is there to know about free radicals and cancer. This is what we will be looking at as we go along this article. These free radicals are organic molecules which are primarily the cause for aging, damaged tissues, and a variety of diseases. The main property that causes them to bind with other molecules in the body there by causing damage is because it is unstable. This is the non-stop process that these molecules will do, destroy cells, takes away its vigor and initiate this pro aging process. In a way it is the natural order of things, our world is filled with so many unstable molecules and just like us, there survival instincts kick in and they have to keep stable. Outside the body, that’s all good, no harm for us, but when the same process occurs inside that’s where our own survival instincts come in and helps us think of ways to stop this process of degeneration. With this degeneration process of cells being damaged, it is not far fetch to see these free radicals as the cause of some disease most especially Cancer.

Cancer

Cancer has been a close second as the top killing disease in America for the past few years now, 2011 is not over yet so there is no ranking out but my guess is, the top 2 will most likely be the same with number one still being heart disease. Cancer is basically characterized by out of control cell growth. There are many classifications of cancer and one thing remains constant, it is characterized or named based on what type of cells it began to damage to cause the eventual cancer. For many of us out there what we do not want to here are malignant tumors in the body and this can occur based on 2 things, when cancerous cells spreads around the body through the bloodstream which is often referred to as an invasion process and the second is when the cancerous cells divide and grow leaving tissues metastasized in a process called mestastasis. Tumors grow and uncontrollably which are lumps of masses that interfere with our normal bodily functions and causes systems to crash like our digestive and nervous systems just to name a few.

The Answer:Antioxidant

Antioxidants has been well known to be one of the best ways to fight cancer, present in many foods, these molecules does its handy work against cancer by going to the source. More research needs to be done in its healing effects but as an effective treatment it has been proven to be an integral part in minimizing further proliferation of damaged cells. Antioxidants have been shown to have an amazing characteristic against free radicals and that it plays an integral role in killing these cell damaging molecules in the body.

List of antioxidants:

This by far a complete list, but it will get you get started with an antioxidant program to help prevent disease caused by free radical damage.

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Natural Vitamins for the Heart
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Date: July 06, 2010 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamins for the Heart

It has been consistently revealed by epidemiological research that individuals with a high dietary intake of antioxidant vitamins have a risk that is lower-than-average of cardiovascular disease. This evidence seems to be especially consistent for vitamin E. Additionally, many clinical studies show that magnesium supplementation is of significant benefit in the treatment of cardiac arrhythmias and in reversing the depletion of potassium that comes along with a magnesium deficit. Many cardiovascular events like angina pectoris, congestive heart failure, and cardiomyopathy are related directly to low magnesium status. Coenzyme Q10 is an essential component in cellular energy production. This nutrient is also prevalent in the heart muscle. When tissue levels of CoQ10 are low, there is an association with several cardiovascular complications. Among these are angina, congestive heart failure, cardiomyopathy, hypertension, and mitral valve prolapse. Research has found that the trio of coenzyme Q10, vitamin E, and magnesium plays a crucial role in the maintenance of cardiac health and the prevention of disease states.

The cardio-protective effect of vitamin E seems to come from its ability to bind to LDL cholesterol, which protects it from free-radical induce oxidative damage along with the consequent buildup of atherogenic plaque. Low levels of vitamin E in the blood are a predictive factor of heart health almost 70% of the time.

Studies on the general population have suggested that there is a link between the intake of calcium and blood pressure. Although results of the studies have not been consistent, there are several studies showing that calcium supplementation can lower blood pressure in those individuals who experience hypertension. Overall, those intakes of calcium that are sub-optimal contribute directly to hypertension. It seems that dietary calcium reduces blood pressure by normalizing intracellular calcium levels.

Supplementation with magnesium is of benefit for the treatment of cardiac arrhythmias and the prevention of potassium depletion. Both magnesium and potassium play an important role in the functioning of the heart. Several studies have found that there is improvement in heart function in those patients that have cardiomyopathies when they supplement with magnesium. Since magnesium acts in so many ways to enhance cardiac function and optimize cellular metabolism, magnesium is widely recognized as a critical nutrient for general cardiac support.

Several double-blind studies have taken place in those patients that experience various cardiomyopathies in order to show the benefits of CoQ10 supplementation. One study reported an 89% improvement rate in 80 cardiomyopathy patients who were treated with CoQ10. The coenzyme also appears to moderate blood pressure through the usual mechanism, as it lowers cholesterol levels and also stabilizes the vascular system with its antioxidant properties. Because of this, it is able to reduce vascular resistance. Several studies on CoQ10 supplementation have confirmed that this nutrient posses the ability lower both systolic and diastolic pressures by up to ten percent.

There are other nutrients that play important roles in optimizing cardiovascular health and reducing hypertension. Among these nutrients are gamma tocopherol, calcium, magnesium, l-carnitine, acetyl-l-carnitine, procyanidolic oligomers, phenolic compounds, and lycopene. As you can see there are many natural supplements that can help the cardiovascular system. Remember to always consult your doctor before adding supplements to your diet while on prescription drugs. Look to your local or internet health food store for quality vitamins, herbs, and specialty formulas to boost your health and wellness.

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Omega Red And Cholesterol
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Date: August 28, 2009 05:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega Red And Cholesterol

Red Omega™ With Red Yeast Rice, CoQ10 & Omega-3 Fish Oils in Softgels

Individually, Omega-3 fatty acids, CoQ10, and Red Yeast Rice extracts have each been shown in numerous studies to exhibit a wide range of cardio-beneficial properties. Until now, anyone interested in reaping the benefits of these three products had limited options, with the exception of purchasing multiple products. Red Omega™ has made it possible for today’s cardiovascularconscious health enthusiast to reap the benefits of all three compounds in one convenient dietary supplement.*

NOW® Red Omega™ is an innovative complex formula that was developed to help support healthy cardiovascular function. Omega-3 Fish Oil and CoQ10 have each been the focus of extensive research, and are now used by millions on a worldwide scope. Combined, however, they exert a powerful synergism that may potentially provide even greater health benefits. The organic Red Yeast Rice in this supplement is carefully produced to avoid the presence of citrinin, a sometimes toxic by-product of the fermentation process.*

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Boost Memory
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Date: March 23, 2009 01:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Memory

Our memory is as natural to us as breathing. An ability we all have, but don’t often think of, it doesn’t seem to cross our mind until we perceive that we are losing the ability. Memory lapses are an annoyance in themselves, but the anxiety that often comes along with them seems to be even worse. We often wonder if our memory problems are a symptom of some other problem like midlife depression, arteriosclerosis, or even Alzheimer’s disease. Although Alzheimer’s disease is a fairly common disorder among older people, one must realize that most memory lapses have nothing to do with Alzheimer’s disease.

Generally, it is believed that increasing age brings about an increased likelihood of developing memory loss. The mildest form of this illness is called age-associated memory impairment. This is characterized by one’s perception of his or her own memory loss and it is estimated that it is experienced by 40 percent of Americans over the age of sixty-five. Not all memory loss is attributable to aging, as occasional memory lapses are a natural normal part of life at almost any age, and are not likely to precede serious memory loss. With a proper diet, nutrition, and memory use, the memory should remain sharp and active well into one’s nineties or beyond.

One big reason why people suffer from memory loss is an insufficient supply of necessary nutrients to the brain. The life of the body is in the blood, as it literally feeds and nourishes every cell within our bodies. Only certain substances are allowed to pass from the bloodstream into the brain, thanks to the protective envelope that is known as the blood-brain barrier. If the blood is thick with cholesterol and triglycerides, the amount of nutrient-rich blood that can pass through the blood-brain barrier decreases. This can result in the brain becoming malnourished over time.

The functioning of the brain also depends upon substances that are referred to as neurotransmitters, which are brain chemicals that act as electrical switches in the brain and are responsible for all the functions of the body. If the brain does not have an adequate supply of neurotransmitters, or the nutrients to make them, it starts to develop something similar to a power failure or a short circuit. If you are trying to recall as specific fact or piece of information and your mind goes blank, it is likely that the above “short circuit” has occurred.

There are many other factors that are involved in the deterioration of the memory. One of the most important is exposure to free radicals, which can cause huge amounts of damage if the memory is unchecked. Alcoholics and drug addicts often suffer a great deal of memory loss, with alcoholics being notorious for huge memory gaps that occur even though they are conscious. Allergies, candidiasis, stress, thyroid disorders, and poor circulation to the brain can also contribute to memory loss, while hypoglycemia can play a role in memory loss as well, as the brain requires that the level of glucose in the blood fall within a specific narrow range. Wide swings in blood sugar levels affect brain function and memory.

The following nutrients are beneficial in dealing with and preventing memory loss: acetylcholine, boron, DMAE, garlic, huperzine A, lecithin granules, manganese, multivitamin and mineral complex, omega-3 fatty acid complex, phosphatidyl choline, phosphatidyl serine, SOD, vitamin A, vitamin B complex, vitamin B3, vitamin C, vitamin E, zinc, acetyl-l-carnitine, l-glutamine, l-tyrosine, coenzyme Q10, DHEA, DMG, melatonin, NADH, pregnenolone, RNA and DNA, Brahmi, ginkgo biloba, anise, blue cohosh, ginseng, gotu kola, and rosemary.

All of the above mentioned as well as formulas tailored to help improve memory can be found in capsule, table, or power forms. Remember, only look to name brands such as Solaray, Source Naturals and Natures Plus for quality products. Memory vitamins and herbs can be found at your local or internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.



--
Vitanet ®. LLC

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Ubiquinol Reduced CoQ10
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Date: April 07, 2008 01:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol Reduced CoQ10

Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.

Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.

In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.

CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.

While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.

In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.

A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.

As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.

The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.

Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.

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Seniors Need More Than a Multiple with Only 100 Percent of the RDA
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Date: January 21, 2008 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Seniors Need More Than a Multiple with Only 100 Percent of the RDA

The aging process is a gradual one. That might seem obvious, and it is, but it is the fact that it is gradual that causes people not to notice the small but significant changes in their body that are taking place. Aging is more than just the oxidation of skin cells that cause them to wrinkle, but involves specific functional cell changes, such as their ability to multiply.

As this slows down the immune system is affected, and we find it more difficult to recover from injury and disease. Oxidation becomes more prevalent and free radicals become more common as the natural antioxidants of our bodies become overwhelmed. We are less able to recover from the effects of environmental stress, such as UV radiation from the sun, pollution and the effects of heat. We find it increasingly difficult to deal with a lack of nutrition or toxins in our food from pesticides. In short, we become less capable of dealing with attack by invaders, but do not notice this gradual lack of immune response.

Age also affects our joints from the vertebrae in the neck to the joints of our toes. The net result is a compression of the bones that causes a reduction in height. We also develop more body fat and less muscle tissue, which is a significant consideration in planning the nutritional needs of the elderly. However, of more critical importance when discussion the nutritional needs of our aging population is the possibility of malabsorption.

Malabsorption is an inability of the digestive system to absorb nutrients from food, and occurs in people of any age although it tends to be more prevalent in seniors. It is predominantly due to a dysfunction of the liver, the pancreas or the small intestine that are the three major physical components of the human digestive system.

The liver produces bile that is needed to process the fats in your food, and if the bile is not delivered to the small intestine, then malabsorption is possible. The same is true of the enzymes that are produced by the pancreas These enzymes are important components in the biochemistry that allow us to absorb nutrition from our food, and since most of this absorption occurs in the small intestine, this too is essential for proper absorption. When any of these three are reduced in efficiency, as they are with advancing years, then malabsorption will occur.

When this occurs in seniors, however, it is essential that a multiple supplement with more than 100% of the RDA (Rcommended Daily Allowance) is used. This type of nutritional deficiency can be very serious at an age when so many normal biochemical processes are slowing down, and it is important that steps are taken to avoid the serious problems that can arise.

The immediate symptoms of malabsorption are diarrhea and weight loss, although the more serious longer term effects are anemia due to a deficiency in folic acid and iron and a reduction in the blood’s ability to form clots due to a deficiency in vitamin K absorption. There are others, but not all problems associated with aging are actually due to malabsorption, or even with aging.

Many of the problems associated with aging are now believed to be connected with the patient’s lifestyle and diet. Heart disease such as atherosclerosis is now known to begin earlier in life, as are many other conditions once believed to be associated with age. A loss of cognitive ability can be age related, but also due to cigarette smoking and excessive alcohol consumption. However, irrespective of all this, it is essential that the aged are provided with vitamin and mineral supplements offering more than 100% RDA.

Calcium is of particular importance for older women who are particularly prone to osteoporosis due to malabsorption of calcium from their food. At least 1000mg daily should be taken, and extra magnesium and vitamins A and E will also be necessary since they are needed for the proper absorption of calcium. The extra does not infer that all of the supplement will be absorbed, but that enough should be to help reduce the possibility of bone density problems.

The elderly are particularly prone to vitamin B deficiencies, particularly of vitamin B12, due to absorption problems and a good vitamin B complex supplement is needed. Chromium too can be seriously depleted in the aged, and this mineral is necessary to enhance the activity of insulin. It is also believed to play a part in the metabolism of carbohydrates, proteins and fats. There are no known consequences of an excess of chromium so a good supplement can be provided. It is believed that vitamin B and chromium together are required for cardiovascular and neurological health that are so important as we age.

One important supplement for the elderly is Coenzyme Q10. Many older people are prescribed drugs such as statins for the treatment of high cholesterol levels. Statins work by depressing the biochemical synthesis of cholesterol by blocking the action of mevalonate, and this is known to interfere with the metabolism of Coenzyme Q10, otherwise known as ubiquinone.

CoQ10 is essential in allowing the production of energy within the cell mitochondria by allowing electron transfer back and forth between NAD and NADH to allow the production of adenosine triphosphate (ATP). A supplement of this important enzyme is therefore essential in maintaining the energy levels of the aged who are being prescribed statins.

Almost 20% of the elderly on prescription drugs are also taking herbal remedies and supplements, and there could be an interaction between them. Anybody taking prescription drugs should consult their physicians before taking natural remedies or any form of supplement, and this is particularly true of the elderly.

However, where the elderly are safely taking a vitamin and mineral supplement, it is extremely important that this contains more than just the RDA. Absorption problems are very common in the elderly, and this excess can make sure that they receive more than they would otherwise, if not the whole recommended dosage of the particular substance involved. Better safe than sorry, especially where an excess is not known to cause harm.

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Vitanet ®, LLC

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Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver
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Date: December 18, 2007 05:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver

Coenzyme Q10 Ultra Potent 400 mg!

Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver

  • A crucial component in the cellular energy production cycle.
  • Research indicates that supplementation with this nutrient may support normal heart function, provide antioxidant protection and support gum health.
  • One of the highest potency CoQ10 products available, for serious nutrition and powerful protection.

1 softgel contains: Coenzyme Q10 (ubiquinone) 400mg

Ubiquinone Coenzyme Q10 is a highly absorbably form of CoQ10. CoQ10 is a powerful antioxidant to help fight oxidative stress which can cause premature aging. CoQ10 is a critical enzyme for cellular energy for all muscles in the body, especially the heart muscle that beats millions of times with out stopping in a lifetime. CoQ10 can help boost brain function, boost immunity, and boost liver function.

For those with gum disease, Coenzyme Q10 can support healthy gums and teeth. Have you had your Coenzyme Q10 today?



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Vitanet, LLC ®

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Kaneka QH - Ubiquinol
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Date: November 30, 2007 03:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Kaneka QH - Ubiquinol

UBIQUINOL COQH

CoQ10 with Heightened Absorption

 

• New, active form of CoQ10 with heightened absorption, which results in increased blood serum levels

• Provides powerful antioxidant support by blocking free radical damage within cell membranes.

• Supports cardiovascular health and energy production by aiding the synthesis of mitochondrial ATP.

• Supports normal, healthy liver functioning by reducing oxidative stress.

 

Source Naturals Offers a New, Premier CoQ10 Product

 

UBIQUINOL COQH bundles all the great benefits of the powerful antioxidant CoQ10 into a superior form that enhances absorption into the body and increases blood serum levels. UBIQUINOL COQH facilitates the production of cellular energy in the mitochondria, which in turn provides robust support to some of the body’s most demanding systems. Both the cardiovascular and liver systems rely heavily on CoQ10 to help generate the energy needed for healthy functioning. Also found in high levels within cellular membranes, CoQ10 works as an effective antioxidant that protects the integrity of mitochondrial and lipid membranes.

 

1 softgel contains:

 

Kaneka QH™ Ubiquinol 100 mg


UBIQUINOL COQH

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Reduce Your Cholesterol With Natural Vitamins
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Date: July 12, 2007 08:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Reduce Your Cholesterol With Natural Vitamins

 

Thanks to the excellent efforts of health education organizations like the American Heart Association, we’ve learned a lot about cholesterol and how it affects our health.

We know: high cholesterol levels increase our risk for heart attacks and strokes: lowering our cholesterol levels will reduce this risk and keep our hearts and blood vessels healthy; and that diet, weight loss, and exercise will all help us in our quest to lower our cholesterol levels. We also know at times, despite these good efforts, some people’s cholesterol levels are still too high.

Prescription drugs to lower cholesterol are now available and they are heavily advertised by the pharmaceutical companies that make them. What the commercials neglect to say is these medications, collectively called statin drugs, have some serious side effects. Statin drugs can cause elevations in liver enzymes, an indication of liver irritation. They are associated with myopathy, a painful disorder of muscle inflammation and muscle degeneration. Ironically, statin drugs significantly reduce CoQ10 levels in the body, a deficit that can lead to heart disease.

Statin drugs have also been linked to a rare and at times, fatal condition called rhabdomyolysis. Because of this alarming link, the makers of cerivistatin, a popular stain drug, recalled this medication from the market on August 8, 2001. The Food and Drug Administration a greed with the recall and supported the decision.

Thankfully, there is a safe solution to the dangers of high cholesterol levels. A natural dietary supplement is now available that can lower cholesterol very effectively without any harmful side effects. Backed by many years of scientific research and clinical study, pantethine and plant sterols, also known as phytosterols, are nature’s answer to dangerous prescription cholesterol lowering medications.

To understand how pantethine and plant sterols work to lower cholesterol levels, we need to first review what we know about cholesterol and heart disease.

 

Q. What exactly is cholesterol?

A. Cholesterol is a soft, waxy, fat-like substance found in every cell of the body. We need cholesterol to help digest fats, strengthen cell membranes, insulate nerves, and make hormones. Cholesterol is made primarily in the liver but also by cells lining the small intestine and by individual cells in the body. While our body makes all of the cholesterol we actually need (about 1,000 milligrams a day), we also get additional cholesterol from foods we eat.

The highest source of cholesterol are egg yolks and organ meats such a liver and kidney. No plant-derived food contains cholesterol, not even peanut butter or avocado, even though these foods are high in fat. However, all foods from animal sources such as meats, poultry, fish, eggs, and dairy products contain cholesterol.

 

Q. How does cholesterol cause heart disease?

A. Although cholesterol serves many important functions in the body, too much cholesterol in the bloodstream can be dangerous. When blood cholesterol reaches high levels, it builds up on artery walls, increasing the risk of blood clots, heart attack, and stroke.

The heart is a muscle, and like all muscles, needs a constant supply of oxygen and nutrients. The bloodstream transports these nutrients to the heart through the coronary arteries. If the coronary arteries became narrowed or clogged by cholesterol and fat deposits (artherosclerosis) and cannot supply enough blood to the heart, the result is coronary heart disease (CHD). IF not enough oxygen-carrying blood reaches the heart muscle, a sharp, sudden chest pain (angina) may occur. If the blood supply to a portion of the heart is completely cut off by total blockage of a coronary artery, the result is a heart attack. This is most often caused from a blood clot forming on top of an already narrowed artery.

 

Q. What is LDL and HDL cholesterol?

A. Cholesterol and other fats can’t dissolve in the blood and, therefore, can’t travel on their own. They have to be transported to and from the cells by special carriers called lipoproteins. The two major lipoproteins are low density lipoproteins (LDL) and high density lipoproteins (HDL). LDL is most often referred to as the “bad” cholesterol whereas HDL is known as the “good” cholesterol.

LDLs carry cholesterol throughout the body to the cells. LDLs cause artherosclerosis by clogging up our arteries with the continual buildup of fat. HDL, on the other hand, prevents this fat buildup within arterial walls, by carrying it away from the arteries, to the liver where it is eventually processed and eliminated.

 

Q. What are triglycerides?

A. Triglycerides are fats used as fuel by the body and as an energy source for metabolism. Triglyceride levels fluctuate easily, changing after every meal. Increased levels are almost always a sign of too much carbohydrate and sugar intake. Triglycerides in high amounts make the blood more sluggish and less capable of transporting oxygen, particularly through the small blood vessels. High triglycerides, along with high LDL “bad” cholesterol, are considered strong and independent risk factors for cardiovascular disease, leading to a heart attack or stroke.

There are several medications physicians can prescribe for people with elevated triglyceride levels. Some of the most effective (as well as the most harmful) are the statins. The powerful, all-natural combination of pantethine and plant sterols can safely and, just as effectively, lower both triglycerides and LDL “bad” cholesterol and increase HDL “good” cholesterol.

 

Q. What is pantethine and how does it lower cholesterol?

A. Pantethine, a form of pantothenic acid (also known as vitamin B5) is found in foods such as liver, salmon, and yeast. Pantethine lowers cholesterol by blocking its production.

Cholesterol synthesis, or the production of cholesterol in the human body, is an incredibly complex process. It involves many biochemical reactions and enzymes activity requiring several steps.

Studies have shown that pantethine inhibits several of these enzymes and coenzymes. It blocks the activity of one coenzyme involved in cholesterol synthesis, HMG-CoA, by about 50%. This results in significantly lower cholesterol production. But, that’s not all. To compensate for the lowered cholesterol production, the liver pulls LDL out of the bloodstream. The end results? Studies have shown that on average, pantethine can lower total cholesterol levels by 16%, LDL cholesterol levels by 14%, serum triglycerides by 38%, and can raise HDL cholesterol by 10%.

 

Q. What are plant sterols and how do they lower cholesterol levels?

A. Plant sterols are the fats of plants. They are found in nuts, vegetable oils, corn, and rice. Plant sterols are structurally similar to cholesterol and are able to act as a stand-in for cholesterol and block its absorption.

The liver receives about 800 mg of cholesterol every day from intestinal absorption. Cholesterol is absorbed from the intestines through receptor sites – special channels that are shaped exactly like cholesterol molecules. The cholesterol enters these channels and is then absorbed into the bloodstream. Because plant sterols look like cholesterol, they fit perfectly into these channels. The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted.

If we eat enough plant sterols, the amount of cholesterol transported from the intestinal tract to the liver is greatly reduced. And, just like pantethine’s effect on the liver, this cholesterol reduction causes the liver to pull LDL cholesterol out of the blood, reducing both total and LDL cholesterol levels.

 

Q. Can’t we get the benefit of plant sterols and pantethine just by eating those foods that contain them?

A. These amounts of plant sterol and pantethine found in food just aren’t enough to have much of an effect on our health. In order to lower cholesterol levels, we need to take a concentrated combination of pantethine and plant sterols in just the right ratio.

Plant sterols are bound in fibers in the plants. Even if we ate lots of raw fruits and vegetables, we wouldn’t be getting many of these beneficial plant fats. There are also several forms of plant sterols. Some ratios of these plant sterols are more beneficial than others. On the average, we eat 160 to 360 mg of plant sterols a day.

While pantethine is found in several food sources, it is difficult to get beneficial amounts from our food. There are about 12 mg of pantethine in 3 ounces of brewer’s yeast and 8 mg in an average serving of liver.

 

Q. How much pantethine and plant sterol combination should I take?

A. Many studies have examined the effects of pantethine and plant sterols on cholesterol levels resulting in the determination of the most effective amounts to take of these heart healthy nutrients.

Manufacturers of high quality nutritional supplements offer pantethine combined with plant sterols in the most beneficial ratio as determined by the research. The best results are obtained by taking a combination of 400 mg of plant sterols and 200 mg of pantethine three times a day.

 

Q. Should only people with actual heart disease or those with high cholesterol levels be concerned about cholesterol?

A. No, recent studies have shown that cholesterol lowering in people without heart disease greatly reduces their risk for ever developing CHD, including heart attacks and artherosclerosis. This is true for those with high cholesterol levels and for those with average cholesterol levels.

Most physicians would never consider prescribing statin drugs to people without actual heart disease or high cholesterol levels because of the many health risks of the drugs. But the combination of pantethine and plant sterols can naturally and very effectively help those people with heart disease, high cholesterol levels, high triglyceride levels (or all three!) as well as those of us just wanting added “health insurance” for our hearts.

 

Q. Are pantethine and plant sterols safe?

A. Yes, both pantethine and plant sterols are very safe. Some people may experience some mild stomach upset when they first take pantethine. Taking the combination of pantethine and plant sterols with meals generally solves this problem.

 

Conclusion

Americans have listened, learned, and most importantly, taken to heart the vast and vital information on the need to keep our cholesterol levels under control. The result? More and more Americans are lucky enough to die of old age. The Centers for Disease Control recently released a report stating that the average American life expectancy has reached a new high of 76.9 years, thanks in no small measure to fewer people who are dying from heart disease,

The authors of this report stated that we could push our life expectancy even higher. We can attain healthy, old age by eating right, exercising regularly, and taking other simple steps to promote good health and prevent serious illness and heart disease. Taking the all-natural combination of pantethine and plant sterols is one simple, yet powerful step, to keep our hearts and blood vessels healthy for a long, long time.



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Vitamins

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Active Coenzyme Q10
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Date: July 07, 2007 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Active Coenzyme Q10

Active CoQ10

 

The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.

In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. What is ubiquinol? Is it the same or different from CoQ10?

A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.

 

Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?

A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.

So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.

 

Q. What are the health benefits of CoQ10 and Ubiquinol?

A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.

In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.

 

Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?

A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.

 

Q. How might ubiquinol be important for the heart?

A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.S. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment. Since ubiquinol is the active form of CoQ10, it may be able to overcome the hurdles to providing maximum impact, most importantly, age and genetic related inefficiencies in converting CoQ10 to active CoQ10 (Ubiquinol).

 

And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.

The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.

Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.

The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.

Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.

 

Q. What have been the results of research studies with Ubiquinol?

A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.

Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Should I take CoQ10 or ubiquinol? How much should I take?

A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.

Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.

 

Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological diseases, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagines. The more we study this naturally occurring compound, the more benefits we find. And with this new ability to provide CoQ10 in its active form, ubiquinol, for the first time, even greater benefits may be derived.

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The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
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Date: May 18, 2007 01:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium

The Awesome Foursome: Coenzyme Q10, L-Carnitine,

D-Ribose, Magnesium

 

The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.

 

Coenzyme Q10:

Energy Recycling through the Electron Transport Chain

Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.

Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.

In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.

What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.

Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.

 

L-Carnitine:

Transporting the Cellular Energy Fuel

Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.

 

D-Ribose:

Rebuilding the Cellular Energy Pool

As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.

When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.

Ribose is the only compound used by the body to refill this energy pool.  Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency.  Ribose is made naturally in the cells from glucose.  In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis.  So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.

    Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy.  Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days.  But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose.  Conditions like ischemic heart disease or congestive heart failure fall into this category.  In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.

 

Magnesium:

Switching on the Energy Enzymes

Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism.  Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work.  Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.

    Magnesium deficiency reduces the activity of important enzymes used in energy metabolism.  Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function.  Small changes in magnesium levels can have a substantial effect on heart and blood vessel function.  While magnesium is found in most foods - particularly vegetables - deficiencies are increasing.  Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.

 

Supporting the Links in The Energy Cycle Chain – the Synergy

Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.

The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.

The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.

Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.

These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.

The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.

L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.



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CoQ10 for Heart Health
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Date: March 28, 2007 12:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10 for Heart Health

CoQ10 for Heart Health

 

More than 40% of all deaths in the U.S. are from cardiovascular disease (CVD). You have a greater chance of dying from heart disease than from cancer, AIDS, diabetes, and accidents combined. More than 2,600 Americans die each day of CVD – an average of 1 death every 33 seconds. One in 5 men and women have some form of CVD. If all forms of major CVD were eliminated, life expectancy would rise by almost 7 years.

One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although CoQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. For what health conditions is CoQ10 used?

A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.

 

Q. Why is CoQ10 especially important to heart health?

A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.

 

Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.

 

Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.

In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.

 

Q. What studies support this fact?

A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

 

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

 

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.s. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment.

 

Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?

A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.

 

The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

 

Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.

 

Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?

A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.

 

While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?

A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:

 

1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.

 

2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.

 

3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at Massachusetts General Hospital and Harvard Medical School.

 

4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.

 

Q. How much CoQ10 should I take?

A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.

 

CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

 

Q. What are some other heart-friendly supplements?

A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.

 

Q. What supplements support healthy blood pressure and cholesterol?

A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.

 

Conclusion

CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.

The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.

Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.

 

 



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Regulating Blood Pressure Naturally
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Date: March 28, 2007 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Regulating Blood Pressure Naturally

Regulating Blood Pressure Naturally

 

High blood pressure (also known as hypertension) affects about 65 million Americans, or about 1 in 3 adults. There are many potential causes of hypertension, but not necessarily any symptoms. In fact, 30% of the people who have high blood pressure don’t even realize it.

In other words, just because you don’t have symptoms doesn’t mean you don’t have high blood pressure. That’s why it’s called “The Silent Killer.” And, make no mistake about it: high blood pressure is dangerous. It is the number one modifiable cause of stroke. Just lowering blood pressure reduces the chance of stroke by 35 to 40 percent. Other conditions, including heart attack and heart failure can be reduced from 25 to 50 percent, respectively.

In this issue of Ask the Doctor, we’re going to talk about high blood pressure and an exciting natural treatment for lowering blood pressure safely and effectively.

Of course, changing blood pressure numbers depends, in a large part, on the choices we make every day – how much we exercise, the foods we eat, and our lifestyle overall. But, for those times we need extra help, there is a new, scientifically-studied supplement to help us along our path to better health and lower blood pressure.

 

Blood pressure guidelines from the National Heart, Lung, and Blood Institute.

Category

Systolic (mm/Hg)

Diastolic (mm/Hg)

Result

Normal

Less than 120

And Less than 80

Excellent!

Prehypertension

120-139

Or 80-89

Make changes in eating and drinking habits, get more exercise and lose any extra pounds.

Hypertension

140 or higher

Or 90 or higher

You have high blood pressure. Talk to your healthcare professional on how to control it.

 

Q. What exactly is blood pressure?

A. Blood pressure is divided into two parts, systolic and diastolic. Systolic is the pressure of the heart beating. Diastolic is the pressure of the heart and vessels filling. When blood pressure numbers are written out, like “120/80,” 120 is the systolic pressure and 80 is the diastolic pressure. The unit of measurement for blood pressure is millimeters of mercury, written as “mm/Hg.”

 

Q. What is considered high blood pressure?

A. A person’s blood pressure can naturally vary throughout the day – even between heartbeats.

However, if the numbers are consistently high (over 120 systolic and 80 diastolic), after multiple visits to your healthcare practitioner, you may have either pre-hypertension or high blood pressure.

Young arteries and arteries that are kept young through healthy diet and exercise are typically more elastic and unclogged. Blood flows through them easily and without much effort. However, as we age, our arteries become more prone to plaque buildup (due to diets high in saturated fat and sedentary lifestyles) and don’t “flex” as well under pressure. The result is faster blood flow, all the time. Over the long term, it damages heart tissue, arteries, kidney and other major organs.

To get a better idea of high blood pressure, compare your arteries to a garden hose. When unblocked, a garden hose allows water to flow through it quickly and easily – without any real rush or stress. However, if you block the end of the hose with your thumb, closing it off even a little, water rushes out much more quickly.

For many years, high diastolic pressure was considered even more of a threat than high systolic pressure. That thinking has changed somewhat but high diastolic numbers could still mean organ damage in your body – especially for individuals under 50.

 

Q. What courses high blood pressure?

A. The reasons for hypertension aren’t always clear. However, there are lifestyle factors that contribute to high blood pressure that you can change:

 

Body type: Weight isn’t always a reliable indicator of whether or not you’ll have high blood pressure – but the type of weight is. Lean body mass – muscle – doesn’t increase blood pressure levels the way that fat can. However, fat body mass, especially fat around your middle, can contribute to high blood pressure.

 

Sedentary lifestyle: Too often, many of us sit down all day at work, and then sit down all night at home. Over time, this inactivity usually leads to weight gain, making the heart work harder to pump blood through the body. In a way, it almost seems contradictory, but inactivity usually leads to higher heart rates.

 

Sodium intake: Sometimes it’s hard to believe how much salt there is in processed foods. However, salt intake in itself is not necessarily bad. For people with a history of congestive heart failure, ischemia, and high blood pressure, sodium is definitely out. For those individuals, it leads to more water retention, which increases blood pressure. (Salt’s effect on water retention is one reason that so many sports drinks have fairly high sodium content – the sodium in the drink prevents your body from sweating out too much water.) But, for healthy individuals, moderate salt intake, especially a mixed mineral salt like sea salt or Celtic salt (good salt should never be white) is fine.

 

Low potassium intake: Unlike sodium, potassium is a mineral which most Americans get too little of. Potassium helps regulate the amount of sodium in our cells, expelling excess amounts through the kidneys. Low levels of this mineral can allow too much sodium to build up in the body.

 

Heavy alcohol intake: Having three or more alcoholic drinks a day (two or more for women) nearly doubles an individual’s chance of developing high blood pressure. Over time, heavy drinking puts a lot of stress on the organs, including the heart, liver, pancreas and brain.

 

Unhealthy eating: Eating a lot of processed or fatty foods contributes to high blood pressure. Adapting a diet that is rich in fruits and vegetables, whole grain products, fish, nuts and magnesium and potassium (like the Dietary Approaches to Stop Hypertension, known as the “DASH” diet) can bring it back down.

 

Smoking: If you smoke, stop. Smoking damages the heart and arteries – period. Nicotine constricts blood vessels, increases heart rate, and raises blood pressure. This in turn, increases hormone production and adrenaline levels, further stressing the body.

 

As if that weren’t bad enough, the carbon monoxide in cigarette smoke replaces the oxygen in the blood, making the heart work even harder to make up the difference. Since the effect of a single cigarette can last for an hour, smoking throughout the day leads to continuously revved-up blood pressure.

 

Some of these factors might sound like a lot to overcome. The important thing to remember is that all of these behaviors are changeable. If you have high blood pressure, modifying any of these can significantly lower blood pressure as part of an overall plan.

 

Q. What are the blood pressure numbers I should see?

A. Experts consider healthy blood pressure numbers to be 115/75 mm/Hg. The reason? They found that the risk of cardiovascular disease doubles at each increment of 20/10 mmHg over 115/75 mm/Hg. Even small jumps in blood pressure numbers increase the risk of stroke and heart attack.

 

Q. Okay, so other than diet, exercise and lifestyle changes are there other natural ways or supplements I can use to lower my blood pressure?

A. Yes, in fact, you hear about some of them in the news all the time – fish oil, CoQ10, and garlic. As effective as these symptoms are, they typically lower systolic pressure much more than diastolic pressure.

However, there is a blend of scientifically and clinically studied natural ingredients that lower high blood pressure separately, and work even better when they’re combined. This combination blend contains: dandelion leaf extract, lycopene, stevia extract, olive leaf extract and hawthorn extract.

Every one of these ingredients has been studied and recommended for years. But now, a scientific study on a supplement that combines them in one synergistic formula shows encouraging results for lowering systolic and diastolic blood pressure.

Let’s take a look at each:

Stevia leaf extract

Supports healthy blood pressure levels according to clinical studies.

Hawthorn extract

Supports the heart and balance sodium and fluid levels.

Olive leaf extract

Scientifically shown to support healthy blood pressure.

Dandelion leaf

Helps reduce fluid retention

Lycopene

Clinically shown to support arteries, circulation and heart health.

 

Stevia:

Stevia (Stevia rebaudiana) originated in South America, and is often used as a sweetener. Glycosides in stevia, particularly stevoside, give the plan its sweet flavor 0 anywhere from 100 to 200 times sweeter than sugar.

The leaf of stevia is considered the medicinal part of the plant. Research shows that extracts of the leaf relax arteries and help prevent the buildup of calcium on artery walls – keeping them healthy and reducing blood pressure.

In a long-term, randomized, placebo-controlled clinical study, stevia reduced systolic and diastolic blood pressure. On average, participants’ blood pressure reduced from baseline 150 mm/Hg to 140 mm/Hg systolic and 95 mm/Hg to 89 mm/Hg diastolic.

And, in another double-blind, placebo-controlled clinical study, stevia lowered blood pressure quite significantly – by an average of 14 millimeters of mercury in both systolic and diastolic readings. Those are impressive numbers!

Despite its role as a sweetener, stevia may have a side benefit to for those with hypertension – blood sugar regulation. Scientific studies show that extracts of stevia regulated blood sugar and reduced blood pressure.

A clinical study showed that stevia extract actually improved glucose tolerance by decreasing plasma glucose levels during the test and after overnight fasting in all participants. Regulating blood sugar is very important for those with high blood pressure. When blood sugar levels are high, blood vessels are inflamed. Many people with diabetes have high blood pressure as well. In a paired, cross-over clinical study, stevioside (one of the compounds in stevia) reduced glucose levels in individuals with type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. It shows great potential in treating type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. Its shows great potential in treating type 2 diabetes as well as hypertension.

 

Hawthorn extract:

Hawthorn (Crataegus spp. Oxycantha) has been used since ancient ties as a medicinal herb – even being mentioned by the Greek herbalist Dioscorides, in the first century AD. Traditionally, it has generally been used for support of the heart. Modern research points to bioflavonoid-like complexes in hawthorn leaf and flower that seem to be most responsible for its benefits on cardiac health, like blood vessel elasticity.

The bioflavonoids found in hawthorn include oligomeric procyanidins, vitexin, quercetin, and hyperoside. They have numerous benefits on the cardiovascular system. Hawthorn can improve coronary artery blood flow and the contractions of the heart muscle. Scientific studies show that the procyanidins in hawthorn are responsible for its ability to make the aorta and other blood vessels more flexible and relaxed, so that blood pumps more slowly and with less effort – sparing the cardiovascular system such a hard workout.

The procyanidins in hawthorn also have antioxidant properties – protecting against free radical cellular damage.

And, hawthorn may also inhibit angiotensin-converting enzyme. Angiotensin-converting enzyme is responsible for retaining sodium and water, and may have roots in our evolutionary development. It influences blood vessel contraction and dilation, sodium and water balance and heart cell development – just about everything that has to do with blood pressure. This may have developed as a way of dealing with periods of drought and stress. By narrowing the blood vessels, the body could guarantee an adequate supply of blood and focus on repairing tissue.

Unfortunately, that can lead to real problems these days. Since many of us live in an industrialized society, and frequently have pretty sedentary lifestyles, conserving sodium just makes the conditions for high blood pressure that much worse.

Like the other ingredients in this combination, hawthorn showed benefits on other body systems, too. In clinical and scientific studies, it not only lowered blood pressure, but also showed anti-anxiety properties and regulated blood sugar.

 

Olive leaf extract:

Olive leaf (Olea europaea) comes up again and again in scientific and clinical studies as having beneficial effects on hypertension. One of olive leaf’s most beneficial compounds is oleuropein – the same compound that makes olive oil so helpful in reducing blood pressure. Here again, we have to look at the traditional Mediterranean diet, which features voluminous use of olives and olive oil. Not surprisingly, blood pressure is generally much lower in Greek and Italian populations.

But it’s not just the diet – scientific studies showed that oleuropein lowered blood pressure by relaxing the blood vessels and prevented buildup of plaque in arteries. Plus, whether in olive leaf extract or in olive oil, oleuropein works as an antioxidant, too.

 

Dandelion leaf extract:

Dandelion (Taraxacum offinale) leaves provide a healthy supply of vitamins, much like spinach. In fact, although it has become the bane of North American gardeners and lawn owners, dandelion greens are a component of many gourmet salads.

Medicinally, dandelion has been used for centuries, dating back to ancient Greece. Leaves intended for medicinal use are harvested before flowering, to ensure the most nutrients.

They are a very rich source of vitamin A, and contain vitamin D, vitamin C, carious B vitamins, iron, silicon, magnesium, zinc and manganese, too. Dandelion leaves produce a diuretic effect in the body, similar to a prescription drug. Since one of dandelion leaf’s traditional uses was the treatment of water retention, it’s really not too surprising. Dandelion leaf is also rich in potassium – one of the vital minerals many Americans lack in their diet. So, even though it may act as a diuretic, it replaces more potassium than the body expels.

The diuretic effect of dandelion can relieve hypertension by drawing excess water and sodium from the body and releasing it through the kidneys as urine. Getting rid of extra water and sodium allows the blood vessels to relax – lowering blood pressure.

 

Lycopene:

If a nutrient can be called exciting, lycopene is it. Lycopene is found mostly in tomatoes and processed tomato products, like pasta and pizza sauce. Related to beta-carotene lycopene shows great antioxidant abilities among its many talents. In fact, it shows even greater free-radical scavenging properties than beta-carotene, its more famous cousin. Healthy intakes of lycopene can guard against a variety of chronic conditions, including lowering LDL (bad) cholesterol, lowering homocysteine levels and reducing blood platelet stickiness that can lead to clogged arteries. It’s even being studied for its protective effect against prostate cancer.

And, for proof, you don’t have to look too far to see the amazing effect lycopene intake can have on health. The Mediterranean diet provides an excellent example. Its high intakes of vegetables, (tomatoes, of course, playing a central role) fish, and whole grains improve cholesterol levels and lower blood pressure. The research on lycopene as a stand-alone nutrient has been compelling. A randomized clinical trial found that not having enough lycopene was associated with early thickening of the arteries.

So, it makes sense that other clinical trials, showed that higher intakes of lycopene frequently meant less thickening of arteries, and a reduced risk of heart attack. In one study, the risk of heart attack was 60% lower in individuals with the highest levels of lycopene. In a multicenter study, similar results were found – men with the highest levels of lycopene had a 48% lower risk of heart attack.

 

Q. What can I expect taking this herbal combination?

A. You should notice both systolic and diastolic numbers lowering in about two weeks. The scientific study showed that for pre-hypertensive and stage I, (early hypertensive individuals) this combination for ingredients lowers both systolic and diastolic blood pressure.

When you’re taking herbs to support your blood pressure, it’s important to keep it monitored so you have an accurate reading (and record) of your numbers. If you need to, you can pick up a home blood pressure monitoring device. These can retail for anywhere from $30 all the way up to $200, but buying one in the $30 to $50 range is a good idea and money well spent. Consider taking the machine to your local doctor’s office or fire department to have it tested for accuracy against a professional blood pressure monitor. See the chart below for tips on getting an accurate reading from a home monitor.

 

Tips for Accurate Blood Pressure Monitoring:

-Relax for about 5 to 10 minutes before measurement.

-If you have just come inside from cold outdoors allow yourself to warm up.

-Remove tight-fitting clothing and jewelry.

-Unless your physician recommends otherwise, use left arm to measure pressure.

-Sit, don’t stand.

-Remain still and do not talk while using the monitor.

 

Q. Are there any side effects?

A. There were no side effects noted in the study. However, because of the mild diuretic effect of dandelion leaf extract, you may notice an increase in trips to the bathroom. It’s always important to make sure you don’t get dehydrated, so you may want to drink more water during the day.

 

Conclusion:

High blood pressure doesn’t happen overnight. As we get older, the likelihood of developing hypertension increases. And, stressful, fast-forward lifestyles, bad diets and no exercise conspire to raise our blood pressure.

 

In my own practice I have helped patients move toward a healthier lifestyle, including diet, exercise, and blood-pressure reducing supplements. They live better, more vibrant lives as a result, and their blood pressure normalizes. It really can happen – you can bring your blood pressure back to normal, and this combination of scientifically and clinically validated ingredients can help.



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How does Sytrinol work?
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Date: February 27, 2007 09:21 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How does Sytrinol work?

Unlike dietary supplements that attempt to block the absorption of cholesterol from the foods we consume, Sytrinol works to balance cholesterol production in the liver naturally. The Sytrinol formula has three different and complementary mechanism of action in the body that deliver heart health benefits without the depletion of CoQ10 common with statin drugs.

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Neurological Health and CoQ10
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Date: February 25, 2007 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Neurological Health and CoQ10

Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.

Q. Isn’t CoQ10 a supplement for heart health?

A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.

Q. How does CoQ10 affect brain health?

A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.

The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.

The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.

Q. What is the blood-brain barrier and why is it important?

A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.

Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.

Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.

Q. If CoQ10 is made in the body, why take supplements?

A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.

Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.

Q. How does CoQ10 help people with Parkinson’s disease?

A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.

A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.

Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.

The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.

The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.

Q. What were the results of clinical research on Huntington’s Disease?

A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.

Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.

Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.

Q. What other diseases could benefit from CoQ10 supplementation?

A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.

In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.

ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.

Q. Can taking CoQ10 prevent neurodegenerative disease?

A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.

Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.

Q. How much CoQ10 should I take?

A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.

CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

Q. What should I look for in a CoQ10 supplement?

A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.

Conclusion

CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.

All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.



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For Better Heart Health ...
TopPreviousNext

Date: February 06, 2007 12:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: For Better Heart Health ...

Nutrients Every Heart Needs

 

High blood pressure. High cholesterol levels. Ever increasing stress. All are factors related to the development of heart disease – the leading cause of death for both men and women. In fact, 1 in 2 women in the United States die of heart disease or stroke, while 1 in 30 dies of breast cancer. If current trends remain unchanged, not only will heart disease remain the primary killer in our country, the number of people it claims will steadily and dramatically increase in the next 20 years.

 

Fortunately, heart disease is a problem you can do something about. Proven ways to prevent or mitigate the effects of heart disease include taking targeted nutritional supplements, making changes in the foods we eat, exercising most days of the week, drinking in moderation, eliminating tobacco use and adapting a positive attitude. Research shows that those of us who are often angry and depressed have more heart disease than people that live their lives with a more positive outlook.

 

In this Ask the Doctor, we’ll talk about specific nutritional supplements that are heart healthy, whether your goal is to prevent heart disease or reduce the effects of heart disease if you currently have it.

 

Q. I am trying hard to live a healthier life. But it all seems so overwhelming. How do I start?

A. It may help to know that you’re not alone in feeling overwhelmed. Lots of people feel this way. This is why the Centers for Disease Control and the American Heart Association are both urging people to prevent heart disease by identifying their individual health risk factors.

 

A risk factor is an indicator of whether or not you may develop a certain health condition. In heart disease prevention, there are two kinds of risk factors. There are risk factor you can control – such as diet, exercise, and the supplements you take. There are also risk factors you can’t change or control –your age, race, and gender, as well as your family’s history of heart disease.

 

Examples can be really helpful. Let’s follow three adults – Fred, Jane, and Earl – and determine their risk factors.

 

Low Risk

Fred is 32, single, has a job he loves, has an optimistic attitude about his life, and works out 5 days a week. Most days Fred’s diet is fruits, vegetables, whole grains and low fat. Occasionally Fred will eat a cheeseburger and fries when he watches the game with his buddies. Fred’s risk factors are his male gender and the occasional high fat content in his diet.

 

Moderate Risk

Jane is 55, a lawyer, married, and has a very stressful job. Jane eats lots of salads, fruits, and whole grains. However, her job requires her to work long hours which leaves little time to exercise. Jane is for the most part happy with her life, but her work stress had led to times of negativity. Her father had a heart attack when he was 56. Jane’s risk factors include her age (greater than 50), negativity from job stress, lack of regular exercise, and a family history of heart disease.

 

High Risk

Earl is 65, married, and has just retired from a job he hated. He spends most of his day watching TV and eating potato chips and other high fat, salty snacks. Earl has told his friends and family since he worked so hard for so long, he is sure to drop dead soon after retiring. He has high cholesterol and high blood pressure. Earl’s father had a heart attack and died when he was 73. Earl’s risk is his male gender, age (greater than 50), sedentary lifestyle, poor diet, negative outlook on life, high cholesterol and high blood pressure, and a family history of heart disease.

 

Q. OK, it’s pretty easy to see that Fred needs to watch his diet, Jane needs to exercise more, and Earl needs lots of help. But, which supplements should they take?

A. The Whole Heart Nutrition chart is an easy way to determine the supplements each risk level needs. As you can see, everyone wanting to prevent heart disease – Fred, Jane, Earl, you, and I – need to take quality heart formula multivitamin, garlic, and a fish oil supplement providing Omega-3 fatty acids. CoQ10 is also a smart choice for complete heart heath support.

 

Q. Why do we all need to take a “heart multivitamin”? Why can’t we take a regular multivitamin to prevent heart disease?

A. Since the human heart simply cannot function without adequate amounts of certain vitamins and minerals, it seems logical that a multivitamin would be the foundation of good nutrition for your heart. Heart-health formulated multivitamins provide the exact nutrients needed to prevent heart disease.

 

That’s why we need to take a specially formulated heart-focused multi-vitamin. The cells and the tissues that make up the heart must have vitamins C, A, and E, as well as B1, B6, and B12 to function. Folic acid, the little B vitamin that is so crucial in preventing spina bifida (a birth defect), breast cancer, and Alzheimer’s disease is also needed to keep heart muscles strong. The B vitamins and folic acid are very important to heart health because they help lower homocysteine levels. Homocysteine is a potential and emerging cardiac risk factor,

 

Magnesium is a mighty mineral and healthy hearts need it every day. Aloha lipoic acid, a fatty acid, provides protection against heart cholesterol and high blood pressure. Lutein and lycopene are all-natural nutrients and keep our arteries free from the buildup of plaque, a condition linked to heart attacks and strokes.

 

Multivitamins formulated with these exact vitamins, minerals, and nutrients will work with medications often prescribed to treat heart disease and provide the nutrition our hearts need.

 

Q. Don’t all multivitamins work with medications prescribed to treat heart disease?

A. Many multivitamin formulas contain herbs and other nutrients that can interfere with prescription medications, especially mediations prescribed to treat heart disease. One multivitamin does not fit all.

The more risk factors you have, the greater your chance of developing heart disease.

Factors you CAN’T change

 

Increasing age

About four out of five people who die of coronary heart disease are 65 or older.

Male gender

Men have more heart attacks than women. Even after menopause, when women’s death rate from heart disease increases, men continue to have more heart attacks until both groups reach their 80s.

Heredity (including Race)

While heart disease has often been noted to occur in families, recent research has shown this link may be the result of environment more than heredity. In other words, your dad’s high blood pressure and your high blood pressure may be related more to your mutual love of salty foods than your genetics. African Americans tend to have very high blood pressure and a higher risk of heart attacks than other races.

Factors you CAN change

 

Tobacco smoke

Smokers have twice the risk of heart attack than nonsmokers.

High blood cholesterol

As blood cholesterol rises, so does the risk of heart disease.

High blood pressure

High blood pressure increases the heart’s workload, causing the heart to thicken and become stiffer.

Physical inactivity

Exercise most days of the week helps prevent heart disease. The more vigorous the activity, the greater your benefits.

Obesity and overweight

People who have excess body fat are more likely to develop heart disease and stroke even if they have no other risk factors.

Individual coping styles

Research has shown there is al ink between heart disease risk and stress, happiness, negativity, and socioeconomic status.

Alcohol consumption

Drinking too much alcohol can raise blood pressure. However, the risk of heart disease in people who drink moderate amounts of alcohol (an average of one drink for women or two drinks for men per day) is lower than in nondrinkers.

 

Q. What can garlic supplements do for Fred, Jane and Earl or other people with low to high risk factors?

A. Garlic supplements have a very long and very successful history of preventing premature death from heart attacks. Lately, however, there have been some conflicting news stories about supplemental garlic’s ability to lower high cholesterol and high blood pressure – the causes of heart disease and death. That’s because many different garlic supplements have been used in these studies – garlic oil, garlic powder, aged garlic extract, and supplements made from fresh garlic. They have all been studied clinically for their effects in heart disease.

 

The best garlic supplements (and the ones that showed the best effects in garlic studies) contain alliin, which is then converted to allicin. Allicin is the compound that lowers harmfully high cholesterol levels and dangerous blood pressure readings. Allicin is also responsible for garlic’s characteristic odor. Because alliin is very stable when dry, properly prepared and enteric coated fresh garlic preparations preserve the allicin-producing action until the garlic mixes with the fluids of the intestinal tract. Fresh garlic extract’s enteric coating also prevents garlic breath. In contrast, aged garlic contains absolutely no allicin or allicin potential. This fact is probably responsible for the poor results noted in lowering cholesterol and blood pressure from aged garlic preparations.

 

The most effective garlic supplements are made from fresh garlic, enteric coated, and provide a daily dose of at least 10 milligrams (mg) alliin or a total allicin potential of 4,000 micrograms (mcg). Taking a once-daily garlic supplement that delivers 4,000 mcg of allicin will lower Jane’s and Earl’s high blood pressure and Earl’s high cholesterol, naturally and effectively.

 

Whole Heart Nutrition

Supplement

Low Risk

Moderate Risk

High Risk

Heart multivitamin

Every day

Every day

Every day

Garlic supplement 4,000 mcg allicin

1 tablet each day

1 tablet each day

1 tablet each day

Fish oil supplement with omega-3 fatty acids

600 mg each day

1200 mg each day

1800 mg each day

CoQ10

60 mg

100-200 mg each day

200-400 mg each day

Each additional risk factor requires additional supplements or increased doses for protection from heart disease.

 

Q. What about fish oil supplements? I know they can prevent heart disease but I’ve also heard they contain harmful substances, too.

A. You’re right on both counts. But, there are excellent fish oil supplements naturally loaded with Omega-3 fatty acids, powerful nutrients that prevent heart disease, that are also certified free of harmful contaminants.

 

In the 1980s, researchers first began noticing the native Inuit (Eskimo) populations of Greenland and Alaska had hardly and heart disease despite a very high-fat diet. The deep-water fish that these peoples eat (and continue to eat to this day) are indeed quite fatty. But, this kind of fat, rich in Omega-3 fatty acids actually protects the heart instead of harming it.

 

Research has shown that the Omega-3 fatty acids in fish oil supplements can:

-Reduce the risk of arrhythmias, lethal heartbeat rhythms that cause sudden death.

-Lower the levels of triglycerides, fats in the blood that can increase a person’s

risk of dying from a heart attack, even if a person’s cholesterol levels are normal.

-Slow atherosclerosis – the growth of harmful plaque on artery walls.

Atherosclerosis develops over many years. If the plaque growth is slow and

stable, chances are low that a heart attack will result. However, rapidly growing

or unstable plaques can rupture. The body responds with inflammation, which

causes blood clots to form. These blood clots block the artery and cause a heart

attack.

-Keep blood pressure levels low. Many people have high blood pressure for years

without knowing it. That’s because it has no symptoms. Uncontrolled high

blood pressure can lead to stroke, heart attack, heart failure, and kidney failure.

While 25% of Americans have high blood pressure, nearly one-third of these

people don’t know they have it. This is why high blood pressure is often called

the “silent killer.”

 

You can get all of this heart disease preventive protection from just 600-1800 mg of fish oil. It’s pretty simple to see why Fred, Jane, Earl, and you and I need to take fish oil supplements every day.

 

However, it is absolutely critical that the fish oil supplement you take is free of contaminants and guaranteed fresh! Make sure that the manufacturer of the fish oil supplement you buy is able to provide documentation of purity in their product. Supplements should contain no detectable dioxin (a widely used toxic preservative), DDT (a toxic insecticide), PCBs (polychlorinated biphenyls) or heavy metals such as mercury and lead.

 

Before you buy any fish oil supplement, ask the clerk if you can open the bottle or jar and smell the contents. A fishy smelling fish oil supplementation means it is rancid. Rancid fish oil is not going to help your heart at all and may actually hurt it.

 

Q. That leaves CoQ10. Why is it important for Jane and Earl?

A. CoQ10, also known as ubiquinone, is the premier heart supplement! CoQ10 is part of our energy producing system. It works directly in the mitochondria of each cell. Mitochondria are highly specialized structures within each cell and are often referred to as powerhouses. These tiny energy producers generate 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. The heart has very important functions and requires a vast amount of energy. Thus, the heart has a lot of mitochondria or little powerhouses.

 

CoQ10 is incredibly crucial to the health of our hearts. Especially to hearts that are pumping blood with too much cholesterol. But, in a dangerous paradox, CoQ10 levels can become dangerously depleted when physicians treat high cholesterol in their patients with certain medications. The so-called “statin” drugs (Mevacor/lovastatin and Crestor/rosubastatin are two examples) are powerful and medications prescribed to lower harmful cholesterol levels. However, one very harmful side effect they share is that they deprive cells of CoQ10. While some physicians are aware of this serious side effect and tell their patients to take at least 400 mg of CoQ10 each day, most are not. The result? Any good the statin drugs may be doing is actually negated by their depletion of CoQ10.

 

Q. How does CoQ10 actually work? Has it been studied in heart disease?

A. Yes, it has! CoQ10 has been extensively studied in heart disease. This natural nutrient is present in every nucleated cell in our body (the only cells that don’t contain CoQ10 are red blood cells). Heart cells, however, are absolutely loaded with CoQ10. Its job is fairly simply – CoQ10 is vital to the production of adenosine triphosphate (ATP), the compound our body uses for 95% of its energy needs.

 

In 1998, 144 patients who had been admitted to the hospital after a heart attack, participated in a CoQ10 study. Half of the patients received 120 mg of CoQ10 a day in addition to the usual treatments given to heart attack patients. The other half, the control group, received the usual treatments and a placebo, but no CoQ10.

 

The results showed that the group taking CoQ10 had less irregular heartbeat, experienced less angina (a type of heart pain), and had much better function in the left ventricle (the most essential chamber of the heart), compared to the placebo group. Total deaths due to sudden heart failure or another heart attack were also reduced in the CoQ10 group.

 

Q. What if I have already been diagnosed with Congestive Heart Failure? Will CoQ10 still help me?

A. CoQ10 has been proven in study after study to help slow down the destruction that occurs in congestive heart failure (CHF), a serious heart disease, and heal the heart muscles damaged by heart attacks. In fact, heart attacks often occur when the body’s CoQ10 levels are low.

 

In a CHF study, patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the researchers introduced a catheter into the right ventricle of the patients’ hearts to determine the degree of muscle damage CHF had caused. In the group who took CoQ10, the pumping ability of the heart improved significantly. The placebo group’s hearts did not. The researchers conducting the study recommended that people with CHF add CoQ10 to the other medications they need to take to stay alive and well.

 

Q. Are some types of CoQ10 better than others?

A. Indeed they are. CoQ10 products are not created equally. The key to this natural medicine is the quality of the manufacturing. Take a CoQ10 supplement that’s been used in research conducted by prestigious universities (it will tell you this right on the label). Researchers want the best CoQ10 for their studies. You want the best CoQ10 for yourself and your loved ones.

 

The best CoQ10 has to meet the following criteria:

1. Must be easily absorbed during the digestion process so that it can get into the

bloodstream.

2. Must reach the mitochondria in the cell.

3. Must be proven effective in studies.

4. Must be safe and free of impurities.

 

Q. It sounds as if CoQ10 is only for people with moderate or high risk factors. Can others benefit from this supplement?

A. Many people, including those like Fred with low risk factors or no risk of heart disease take CoQ10 every day. CoQ10 supplements may reduce your risk of cancer, prevent gum disease, and help certain nerve cells work more effectively.

 

Conclusion

Understanding your personal risk factors, making it better lifestyle choices, taking a multivitamin formulated for your heart, an enteric-coated fresh garlic supplement, fish oil supplement with Omega-3 fatty acids, and CoQ10 – the heart’s super-nutrient – can help keep your heart healthy and strong.

 

Helen Keller, the famous lecturer and author, who was both blind and deaf wrote, “The best and most beautiful things in the world cannot e seen or even touched. They must be felt with the human heart.”

 

Healthy hearts have the most opportunities to “feel” the best and are the most beautiful thing our world has to offer.

 



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Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.
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Date: November 09, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.

For some people the constant tingling in their feet is the worst part. Others feel like their feet are being stabbed or burned, or that their extremities are simply lifeless. All these folks suffer from peripheral neuropathy, nerve damage that afflicts nearly 30% of people with diabetes aged 40 and older. And if the discomforting sensations are not enough, neuropathy can lead to falls, wounds that won’t heal, even amputation.

Untold numbers of individuals have been helped by alpha lipoic acid (ALA), a supplement that European practitioners have used as a standard neuropathy treatment for 30 years. ALA (also known as thioctic acid) assists in the chemical reaction that generates energy within cells. It serves as a universal antioxidant—a substance that can fight tissue-damaging free radicals in both the fatty watery parts of a cell-and helps the body create additional free radical fighters, such as glutathione. ALA can even help regenerate several other antioxidants, including coenzyme Q10 (CoQ10) and vitamins C and E.

Defying diabetes

People with diabetes need antioxidant protection as much as anyone. Fortunately for them, though, ALA fights this insidious disorder in many other ways.

Diabetes occurs when the body can no longer effectively use glucose (blood sugar), its main energy sources; ALA helps shepherd glucose out of the blood and into cells. It also interferes with glycosylation, a process in which glucose sticks to proteins such as the low-density lipoprotein (LDL) that carries cholesterol through the bloodstream. That’s important because this “sticky” LDL can adhere to arterial walls, creating a major risk factor for heart disease. ALA combined with exercise appears to make insulin, the hormone that controls glucose usage, more effective. What’s more, early research indicates that ALA can deflect another cardio hazard by interfering with the ability of salt to push blood pressure upward (molecular and Cellular Biology 12/03).

ALA Annotations – what is it? Alpha Lipoic acid, a substance the body creates naturally.

What it Does: ALA, a powerful antioxidant in its own right, plays a vital role in the creation and renewal of other antioxidants. It is used to treat peripheral neuropathy; nerve damage caused by diabetes, and is also under investigation for possible therapeutic effects in other disorders, including multiple sclerosis and age-related cognitive decline.

Diabetes doesn’t just attack the nerves and the heart—its effects are felt throughout the body. That’s why scientists are examining whether ALA can tackle other diabetic complications: in lab studies it has forestalled diabetes-related kidney and eye damage. (Check blood-sugar levels regularly when using ALA, especially if you’re taking other glucose regulators.)

Protecting Nerves

While diabetes is one of the most common causes of nervous system damage, it isn’t the only one. In test tube studies ALA has promoted chemical reactions that encourage neurons (nerve cells) to survive and grow; as a result some scientists believe this natural antioxidant may eventually play a role in treating degenerative nerve disorders. Such research is in its beginning stages, but the results are still intriguing. For example, in mice ALA has slowed progression of a disorder that mimics multiple sclerosis in human beings (Journal of Neuroimmunology 3/04) and improved age-related memory loss when used with N-acetyl-cysteine (NAC), another antioxidant supplement (Journal of Neurochemistry 3/03). A number of other conditions that become more common with age may also benefit from ALA, including arthritis and thinning skin.

If you suffer from both diabetes and the nerve damage it causes, ask your practitioner about ALA. It just may help your feet and the rest of you feel happy. –Lisa James



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Lower Cholesterol Naturally!
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Date: October 06, 2006 09:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lower Cholesterol Naturally!

Because of organizations like the American Heart Association (AHA), we’ve learned a lot about cholesterol and how it affects our health. Thanks to these educational organizations, we know that high cholesterol levels can increase our risk for heart attacks and strokes and, by lowering these levels, we reduce these risks as well as keep our hearts and blood vessels healthy. We also know that our cholesterol levels can be improved through exercise, diet, and weight loss.

Although we’ve learned a lot through these educational organizations, there are still a few misconceptions about cholesterol. One of these being that not all cholesterol is harmful. There are both “good” and “bad” forms of cholesterol and a good balance between the two is what is needed for a healthy heart. Because so much emphasis is placed on lowering “bad” cholesterol levels, not enough attention is paid to the benefit of raising “good” cholesterol levels (HDL). Research states that raising HDL levels can provide even greater protection against cardiovascular disease than just simply lowering “bad” cholesterol levels. By raising HDL levels by simply 1%, the risk of heart disease can be lowered by 2% in men and 3% in women. Many studies have shown that low HDL cholesterol levels are an independent risk factor in heart disease. This is extremely important because we’ve learned that despite efforts to change a person’s diet and exercise habits, some people’s cholesterol levels are still unhealthy.

Prescription drugs to lower cholesterol are now available and have been proven by multiple studies to be very successful. The statins’ effectiveness in reducing LDL (“bad”) cholesterol has produced highly significant reductions in heart attacks and strokes. Although these medications do lower cholesterol levels, their side effects must be considered. Statin drugs can cause liver irritation, reduce CoQ10 levels in the body, are associated with myopathy, and are even linked to a rare and sometimes fatal condition called rhabdomyolysis. These drugs also have a relatively small effect on good (HDL) cholesterol levels. Thankfully, there are safe and effective solutions available that can help you manage your cholesterol levels naturally. However, first we must review what we know about cholesterol and heart disease.

Cholesterol is a fat-like substance needed to help digest fats, strengthen cell membranes, make hormones and insulate nerves. Although it is found in every cell of the body, cholesterol is mainly made in the liver, as well as cells lining the small intestine. Even though our bodies make all the cholesterol we need, we also get cholesterol from the foods we eat, such as egg yolks and organ meats. All foods from animal sources contain cholesterol, while plant derived food, including peanut butter and avocado, contains no cholesterol at all.

Cholesterol is important to many functions of the body. However, too much cholesterol in the bloodstream is extremely dangerous. After blood cholesterol reaches high levels, it builds up on the artery walls, and thus increasing the risk for blood clots, heart attack, and stroke. If the cholesterol clogs any of the coronary arteries, the heart’s supply of oxygen and nutrients will diminish, resulting in coronary heart disease, angina, or even heart attack.

Because cholesterol and other fats can’t dissolve in the blood and thereby can’t travel on their own, they have to be transported to and from the cells by lipoproteins. The two major lipoproteins are low density lipoproteins (LDL or “bad cholesterol) and high density lipoproteins (HDL or “good cholesterol”) LDLs carry cholesterol throughout the body to the cells and cause artherosclerosis by clogging up our arteries with fat. On the other hand, HDL prevents the fat buildup by carrying it away from the arteries and to the liver where it can be eliminated. Although high levels of LDL are associated with cardiovascular disease, high HDL can drastically reduce your risk of heart disease. As a result, the AHA has established three guidelines to keep your heart healthy: HDL levels about 40 for men and above 50 for women, LDL levels between 100 and 159, and a total cholesterol (HDL and LDL) of under 200.

Triglycerides are fats used as fuel by the body and a source for metabolism. These levels can fluctuate easily but increased levels are almost always a sign of too much carbohydrate and sugar intake. High amounts of triglycerides make the blood less capable of transporting oxygen and are another factor for cardiovascular disease. Thankfully, the HDL and LDL blend mentioned earlier can safely and effectively lower triglyceride levels.

It has been shown that high levels of HDL cholesterol are inversely related to coronary artery disease risk. However, what people do not know is that there are different subtypes of HDl, including HDL-2 and HDL-3. HDL-3 is produced by the liver and intestines and is responsible for scooping up free cholesterol from the blood vessel walls. The cholesterol carried by HDL-3 is chemically modified, forming a larger-sized subtype, known as HDL-2, or “mature HDL.” HDL-2 transports cholesterol to the liver for processing and elimination, and its molecules are then recirculated in the blood stream. Research has shown that HDL-2 provides more heart-protection because it moves the cholesterol away from arterial walls, and holds a greater number of receptor sites which allows it to carry a larger amount of cholesterol to the liver.

Although many prescription medications have been developed to lower bad cholesterol, there are very few medications that target good cholesterol. Therefore, patients with naturally low HDL cholesterol, who can not alter these levels through diet and exercise, have limited medical options to reduce their risk of heart disease. Multiple nutrients have been clinically shown to favorably alter good cholesterol levels including: vitamins C, E, B6, B12, niacin, folic acid, magnesium and selenium, with protein-building amino acids, powerful antioxidants such as coenzyme Q10, alpha lipoic acid, N-acetyle cysteine, and policosanol, and extracts of hawthorn, garlic, grape seed, and soy isoflavones. Although this HDL-boosting combination does not result in a significant reduction in LDL, antioxidants found in this formulation can help stabilize LDL and prevent build up in the arterial wall.

This formula combines essential vitamins and minerals, at levels recommended by the American Heart Association. It contains amino acids, antioxidants, and botanicals that have all been used safely for years. No serious adverse effects have been found following supplementation and the combination is safe to use with statin drugs.

Plant sterols, found in nuts, vegetable oils, corn, and rice are structurally similar to cholesterol and are able to block its absorption. Each day the liver receives about 800 mg of cholesterol from intestinal absorption through receptor sites. After entering these channels, the cholesterol is absorbed into the bloodstream. Since plant sterols look similar to cholesterol, they fit perfectly into these receptor sites and block the absorption, which allows the cholesterol to remain in our intestines where it can eventually be excreted. A large amount of plant sterols reduces the amount of cholesterol transported from the intestinal tract to the liver. This cholesterol reduction causes a decrease in LDL levels.

Even if a person does not have high cholesterol levels, reducing bad and raising good cholesterol greatly reduces their risk for ever developing chronic heart disease. Due to side effects, physicians do not normally prescribe statin drugs to people without actual heart disease of high LDL cholesterol levels. Instead, they recommend dietary changes. The HDL-boosting combination and LDL-lowering pantethine and plant sterols blend can effectively help people with heart disease, uncontrolled cholesterol levels, high triglyceride levels, or people who just want to improve their heart health.



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What are you really Getting?
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Date: August 21, 2006 05:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are you really Getting?

 

Supplement labels can be confusing!

 

The list of ingredients on some supplement labels can tax the mind of even a Ph.D. in nutrition!  What’s worse, although labeling laws exist to counter misleading and non-uniform labeling, confusing and deceptive labeling, confusing and deceptive labeling practices continue to abound.  Here’s some help to aid you in making better sense of supplement labels.

 

1.Begin at the Bottom

 

The supplement facts panel on the label of every nutitional supplement sold in the U.S. tells you about active ingredients in a product. Before analyzing this information, look beneath the panel, where the OTHER INGREDIENTS are listed.  Here, at a glance you can begin to spot a questionable product.  Synthetic colors, flavors, preservatives, or the absence of certain information, are early warning signals. 

 

Poor Label

 

 

Good Label

1.other ingredients: Cellulose, stearic acid, sucrose, sodium, silicoaluminate, talc, titanium dioxide, mineral oil, FD&C red #40, FD&C yellow, aluminum lake, polysorbate 80.

  1. other ingredients: Cellulose(capsule), vegetable magnesium state, silica.
  2. this product contains no gluten, wheat, yeast, eggs or dairy, no synthetic colors or flavors , and no toxic levels of lead or other heavy metals.
  3. Lot# 123456

Expires: 01/08 or use by: 01/08

 

 

  1. Other Ingredients: supplements can be natural only by degree, since their manufacture often requires the use of binders, flowing agents and other items.  Such materials may come from natural and artificial sources. They must be listed in descending order by quantity.
  2. Contains No / May Contain:  Sometimes, supplements are derived from sources that could cause reactions in allergic individuals (eg. Soy, shellfish).  Better labels tell you which allergens are absent, as well as those which may be present.
  3. Expiration date & lot Number: shelf life varies fro different supplements, but most will diminish in potency and quality over time.  Better labels provide a USE BYE or EXPIRATION date.  They also note a LOT NUMBER for identifying product origin (for tracking any product related problems).

 

2.Directions, Dose & Value

 

Poor Label

 

Good Label

 

DIRECTIONS: Take 6 tablents daily, two with each meal.

 

Directions: Though not required on labels, directions tell how and when to take supplements.  This is important because timing your doses can affect absorption. In general:

 

·        Vitamins are best absorbed when taken with food, and in divided doses throughout the day.

·        Fat-soluble vitamins (A,D,E,K) require dietary fat for absorption, so are best taken with meals.

·        Many minerals can be absorbed effectively at any time.

·        Most herbs, probiotics, amino acids & proteolytic enzymes (not digestive enzymes, which should be taken with meals) are best taken on an empty stomach.

 

Poor Label

Good Label

Supplement facts

    1. serving size 3 tablets
    2. servings per container 20
    3. % DV (Daily Value)

Supplement facts

1. Serving Size 2 Tablets

2. Servings per container 30

3. % DV (Daily Value)

 

1. Serving size: SERVING SIZE is required on labels. It recommends the number of tablets, capsules, spoonfuls, ect. Taken at one time.  Be ware that a serving is not necessarily the total recommended daily amount.

 

2.      Cost-Effectiveness: To determine, first find the SERVING SIZE.  Then read the directions to see how much servings are suggested daily.  Finally, divide the number of servings needed into the number of SERVINGS PER CONTAINER.

 

Example: Assuming the two bottles above have the same ingredients and cost. The product on right offers more servings, and is a better buy. Product on left just has less nutritive ingredients, or more filler, in each pill.

 

3.      % DV (Daily Value): The daily value of a nutrient represents the amount expected to meet the daily needs of an “average” healthy person.  On labels, % DV indicates provided by one serving.  DVs have not been established for herbs, essential fatty acids and other nutrients.

 

Note: Many experts in nutrition think that suggested DV levels for some nutrients are far too low to optimize health.  This is why certain ingredients may be present at greater than 100% DV levels.

 

3.Games Labels Play

 

There is no free lunch in the world of supplements.  A bottle that costs less probably contains less – either fewer nutrients, or less effective forms of nutrients.  Educate yourself; compare ingredient amounts, forms and sources, and watch out for labeling tricks such as these.

 

“Padding” the label

 

padding” the label is a common way for supplement marketers to make their ingredients list look more complete and beneficial than it really is.  Padding methods include:

 

Poor Label  amount per serv.

Good Label  amount per serv.

1.CoQ10……….1000mcg

2.Oat Bran………20mg

   Oat fiber……….1mg

3. Oat flavonoids…25mcg

1. CoQ10………….50mg

 

  1. Pixie Dust:  Adding useful ingredients in therapeutically useless amounts. Some brands use tiny amounts of nutrients just to get the ingredient on the label.  Learn how much nutrient is required, and be watchful of inappropriate measurement sizes. (See Weights & Measures below.)

 

Example: CoQ10 useful range is 30mg to 400mg (milligrams.)  product on left provides 1000mcg  (microgram) of CoQ10, the equivalent of just one mg!  product on right provides a beneficial 50mg.

 

  1. Sounds Good:  Adding impressive but irrelevant ingredients, often in useless amounts, that are of no benefit to the formula.

Example: Whole grains such as oats are part of a heart healthy diet, but the product on left provides less than a pinch 20mg of oat bran.  Product on right includes no irrelevant ingredients in useless amounts.

 

  1. Expanding Assets:  Separately listing the parts of a single ingredient to give the illusion of additional ingredients. 

Example: Fiber and flavonoids are part of oats, not more ingredients.

 

The “Name’s the Same” Game

 

A common trick is to provide unproven, weak or useless forms of familiar, good ingredients.  Buyer beware!

 

Poor Label  .

Good Label   .

Pygeum Bark Powder

Pygeum Africanum…..100mg

Pygeum Bark Extract

Pygeum Africanum (Standardized to 13% total sterols……….100mg

 

Example: Studies suggest that Pygeum bark standardized extract helps support prostate health.  Product on left uses unresearched powdered bark.

 

 

Proprietary Blend = “It’s a Secret”

 

Some companies may hide the quantity and quality of their ingredients by calling their formula  a “Proprietary Blend.”  This term may allow manufacturers to use a lot of nutrient from a cheap source and very little from a good source without disclosing how much of each you are actually getting. 

 

This deceptive practice is legal—as long as the secret blend:

·        Is labeled “Proprietary Blend” (or fanciful trademark name)

·        Lists individual nutrients in descending order by weight

·        Lists the total weight per serving

 

When you see the word “Proprietary,” ask: “how relevant is the first or second ingredient?”  Sometimes, the most abundant ingredients are either fillers, or inexpensive, less effective forms.

 

Poor Label              amount per serv.

 

Good Label             amount per serv.

Special Proprietary Women’s Blend

Alfalfa herb, Black Cohosh root, Chaste Tree berry, Dong Quai root, Licorice root………….350mg

Black Cohosh root

Cimicifuga Racemonsa (2.5% total triterpene glycosides)…….125mg

Chast Tree berry

Vitex agnus-castus (0.5% agnusides)………………..100mg

Dong Quai root

Angelica sinensis (5:1 extract)..75mg

Licorice root

Glycyrrhiza glabra……………50mg

Example: Legally, product on left could contain 99% alfalfa filler and only 1% of all the other herbs together! The Good Label tells all.

 

Hiding Outside the Box

 

Another clever way to hide the quality of ingredients is by listing them outside the Supplement Facts box, in the Other Ingredients section located beneath the box.  This section is usually intended for listing agents used in the tableting or encapsulation process.

 

 

Poor Label

 

Good Label

Other Ingredients: Cellulose, stearic acid, spirulina, lycopene, grape seeds.

Other Ingredients: Cellulose, vegetable magnesium stearate.

Example: Agents used in supplement manufacture (i.e. cellulose and stearates) should be listed under Other Ingredients.  Product on left also uses this section to list catchy sounding spirulina, lycopene, and grape seeds.  With no amounts listed, assume these ingredients are present in low levels that provide little value.  A supplement maker who is proud of a product’s nutritive ingredients will fully disclose amounts within the Supplement Facts box not list these ingredients along with manufacturing agents in the Other Ingredient section.

 

4.Understanding Herbs

 

 

Herb Forms: Powders, Tinctures, Extracts

 

The form, preparation and concentration of an herb affects its potency and influences the herb’s potential for therapeutic effectiveness.  the potency of all herb forms except standardized extracts are uncertain and depends on factors invisible to the consumer (i.e. soil quality, rainfall, seasonal climate, harvesting methods, storage methods and age).

 

            Know Your Plant Parts: Medicinal plants often have specific parts that are most effective therapeutically, such as the root for goldenseal, the leaf for raspberry, and the blossom for clover.  Products using irrelevant plant parts may cost less, but offer little or no benefit!

 

Powdered Herb

 

Often encapsulated or used as tea, powdered herbs are more likely than other forms to lose potency when exposed to air.  Fresh, high quality powdered herb may add therapeutic or nutritional value to a supplement.  Low quality powders may provide little benefit.  Look for expiration or “use by” dates.

 

Poor Label

 

Good Label

Saw Palmetto………..320mg

Saw Palmetto berry

Serenoa repens……320mg

Example: If the label doesn’t say otherwise, assume the form of herb is powdered.  Better labels specify plant part and latin name (genus and species).  Sometimes a less effective species of a plant is used to save money.  Check to see if other related species may be equally effective.

 

Tinctures and Fluid Extracts

 

Tinctures contain the soluble parts of dried or fresh herbs, often extracted in a mixture of alcohol and water, vinegar or glycerin.  Tinctures are usually dispensed by drops. This form is more stable and thus has longer shelf life than powdered herb.

 

Poor Label

 

Good Label

Saw Palmetto berry

Tincture…………..320mg

Saw Palmetto berry

Serenoa repens 1:5 tincture, 40% alcohol………………..320mg

Example: Better labels specify tincture strength as a ratio.  Regular tinctures are made using 1 or 2 parts herb to 10 parts solvent, yielding strength ratio of 1:10 or 1:5.  higher potency tinctures (also known as fluid extracts) use more herb in less solvent, yielding stronger 1:3, 1:2, or even high strength 1:1 ratios.

 

Concentrated and standardized extracts

 

Concentrated or standardized extracts (solid, powdered, liquid) are generally prepared from evaporated herbal tinctures or teas.

 

Poor Label

 

Good Label

  1. Saw Palmetto Berry Extract..……..320mg
  2. Saw Palmetto berry standardized extract………..320mg
  1. Saw Palmetto berry

Serenoa repens extract 5:1…………320mg

  1. Saw Palmetto berry

Serenoa repens (standardized to 85%-95% fatty acids and sterals)………320mg

 

  1. Concentrated extracts commonly use 4 to 8 parts of plant matter to make 1 part extract (4:1 to 8:1).  Some may use up to 200 pounds of herb to make 1 pound of finished product (200:1)!

Example: A better label tells you the concentration strength by noting the ratio of herb to extract.  This is often appears after the plant name.

 

  1. Standardized Extracts are lab-analyzed to provide a verified amount of one or more nutritive ingredients.  In many cases, proportional amounts of other constituents are also present, retaining the natural “fingerprint” of the whole herb.  Standardized extracts are the most consistent, and often the most potent, form of an herb.  They are used in the majority of studies demonstrating therapeutic effectiveness.

Example: Standardized extracts provide a set percentage of an herb’s researched nutritive ingredient.  Useless this percentage is noted on the label, the term “Standardized” is meaningless.

 

5.Beware of False Claims

 

Is it science of is it marketing?  To avoid being misled, question all claims on supplement labels as well as in advertisements.  Although government guidelines restrict the types of claims that manufacturers can legally use to promote their products, not all companies comply.  Many promises mount to little more than marketing hype.

 

Use common sense to decide if a claim seems realistic.  Be aware of emotionally charged, misleading language in advertising.

 

When doubt, contact the company and request information to support a claim.  Unbiased research and human studies are most relevant.  If the science seems legitimate, verify that the form and dose used in product match form and dose showing benefit in studies.

 

Weights & Measures

1 kilogram (kg) = 1000grams (g)

1 gram (gm) = 1000 milligrams (mg)

1 milligram (mg) = 1000 micrograms (mcg)

1 liter = 1000 milliliters (ml)

946 milliliters (ml) = 1 quart

30 ml = 1 fluid once

1 teaspoon, medical = 5 milliliters (ml)

1 tablespoon = 15ml = ½ fluid ounce

28.35 grams (gm) = 1ounce

1 kilogram = 2.2 pounds

Vitamin E

Measured in mg alpha-tocopherol equivalents 1 mg alpha tocopherol = 1.49 IU

Beta Carotene 1mg = 1667 IU

Vitamin A

1 RE (retinol equivalent) = 5 IU

1 RE = 6mcg of beta carotene

1 RE = 1mcg of retinol

Vitamin D

Measured in mcg cholecalciferol

1 mcg cholecalciferol = 40 IU

 

 

 



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HDL Booster - Boost your good cholesterol
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Date: March 16, 2006 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL Booster - Boost your good cholesterol

 

                                      

 

 

HDL BOOSTER

(Product No. 02922)

 

 

 

DESCRIPTION:

 

HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*  

 

HDL Booster:

 

·         Formulated by Dr. Dennis Goodman, Chief of Cardiology at Scripps Memorial Hospital

·         Clinically studied to increase good cholesterol levels up to 23%*1

·         All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association

·         Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2

 

STRUCTURE/FUNCTION:

 

HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*  

 

FORMULA:

 

Two tablets (one serving) contain:

 

Vitamin C (ascorbic acid)                                                          148 mg

Vitamin E (as natural mixed tocopherols)                                    35 IU

Niacin (as niacinamide)                                                              21 mg

Vitamin B6 (as pyridoxine HCl)                                                  3 mg

Folic Acid                                                                                 301 mcg

Vitamin B12 (as cyanocobalamin)                                              20 mcg

Magnesium (from magnesium amino acid chelate)                       10 mg

Selenium (as L-selenomethionine)                                               49 mcg

Proprietary Blend                                                                      388 mg

   hawthorn (Crategus oxyacantha) berry extract,         

   taurine, garlic (Allium sativum) bulb, grape seed (Vitis

   vinifera) extract, grape skin (Vitis vinifera) extract,

   N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine

   max) isoflavones, tocotrienols

L-Arginine (as L-arginine HCl)                                                  153 mg

L-Carnitine (as L-carnitine L-tartrate)                                        51 mg

Coenzyme Q10 (CoQ10)(ubiquinone 10)                         25 mg

Policosanol                                                                                7 mg

 

Other ingredients: See label for most current information.

 

Contains no: sugar, salt, yeast, wheat, gluten,  corn, dairy products, artificial coloring, artificial flavoring, or preservatives.  This product contains natural ingredients; color variations are normal. 

 

INTRODUCTION:

 

Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5

 

Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4

 

Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4

 

Types of Cholesterol

 

Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5

 

LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6

 

Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7

 

The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7  

 

HOW IT WORKS:

 

HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9

 

Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at Scripps Memorial Hospital to evaluate the effects of a proprietary supplement on lipid profiles. The dietary supplement, which mirrors HDL Booster and contains a combination of antioxidants, B-vitamins, amino acids, and botanical extracts, was developed by Dr. Goodman, the leading cardiologist at Scripps. The trial involved 50 people, who were evaluated prior to the study, then again at three and six months. After three months of supplementation, good cholesterol levels increased in all groups.* The changes were more pronounced at the six-month time point, where good cholesterol rose up to 23 percent and levels of HDL-2 (the best cholesterol) increased 50 percent in one subset of participants (HDL <40 mg/dL).*1 Additionally, the supplement also helped maintain healthy triglycerides levels that were already within the normal ranges.* Decreases in homocysteine, an amino acid found in the blood that plays a role in cardiovascular health, were observed as well.*1,10

 

The following chart summarizes the benefits of each of the ingredients in HDL Booster:

 

Ingredient

Benefit

Vitamin C

An antioxidant clinically shown to support the health of the cardiovascular system and increase HDL-2 cholesterol levels.*11,12 An important factor in many metabolic reactions, including the conversion of cholesterol to bile salts and the formation of healthy connective tissue. Vitamin C provides protection for the inner lining of the arteries.*13,14

Vitamin E

Another powerful antioxidant, which inhibits the oxidation of low density lipids by inactivating free radicals.* Thought to inhibit the breakdown of certain fatty acids that help form cell structures, especially membranes13

Also supports healthy cholesterol levels already within the normal range.*15,16

Niacin

In lipid metabolism, supports normal cholesterol production and metabolism to help retain healthy cholesterol levels that are already within normal limits.*13 Increases good cholesterol levels, particularly HDL-2 (the best cholesterol).*17 Through peripheral vasodilatation, niacin also supports the retention of healthy blood pressure that is already within the normal range.*13

Vitamin B6

An essential coenzyme for normal amino acid metabolism. In particular, vitamin B6 is necessary for the breakdown of homocysteine, an amino acid that plays a supporting role in cardiovascular health.* Also involved in the production of circulating antibodies.13 High levels of circulating vitamin B6 have been associated with reduced levels of C-reactive protein, another important indicator of heart health.*18

Folic Acid        

Another homocysteine lowering agent, folic acid is essential for the formation of red and white blood cells and involved in the synthesis of certain amino acids.*13

Vitamin B12

A ubiquitous coenzyme necessary for DNA synthesis. Also lowers homocysteine levels.*13

Magnesium

Increases HDL levels, supporting a healthy lipid profile, and helps maintain healthy blood pressure already within the normal limits.*19 Magnesium is a constituent of many coenzymes and is required for normal functioning of muscle and nervous tissue.20

Selenium

An essential trace mineral with powerful antioxidant capabilities.*20 Research has revealed that selenium supports cardiovascular function.*21

L-Arginine

An important amino acid and precursor to nitric oxide (NO), which is important for the health of the cardiovascular, immune, and nervous systems.*22 In clinical study, an L-arginine-enriched diet increased good cholesterol levels.*23

L-Carnitine      

A naturally occurring hydrophilic amino acid derivative, both produced in the kidneys and liver and derived from dietary sources. Along with coenzyme Q10, L-carnitine is a key factor in metabolism, supporting the production of cellular energy.*24 Also shown to increase good cholesterol (HDL) levels.*25 L-carnitine supports healthy blood flow.*26

Coenzyme Q10 (CoQ10)

A fat-soluble nutrient present in the mitochondria of virtually all cells, CoQ10 is an essential factor for cellular energy production.27 Also a powerful free radical scavenger, clinically shown support arterial health.*27,28

Supplementation significantly improves good cholesterol levels.*29 Additionally, CoQ10 supports healthy heart contractility and circulation.*

Policosanol

A unique mixture of essential alcohols, including octacosanol, tetracosanol, hexacosanol and triacontanol, derived from sugar cane.30 In a clinical study, supplementation resulted in a 14 percent increase in HDL cholesterol over an 8-week period.*31

Hawthorn Berry Extract

Helps retain healthy cholesterol levels already within the normal range.* Supports the muscle strength of the heart, helping to maintain healthy heart rhythm, contractility, and vascular circulation.*32 A source of antioxidant constituents that protect against oxidative damage.* Supports the health of veins and arteries.*33,34 Also helps maintain healthy blood pressure levels already within the normal ranges.*

Taurine

An essential amino acid, present in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. Possesses both antioxidant and membrane-supportive properties.*35 Helps maintain a healthy lipid profile by increasing good (HDL) cholesterol levels.*36,37

Garlic Bulb

A powerful antioxidant that possesses wide-ranging cardiovascular health benefits.*38 Clinically shown to increase good cholesterol levels, particularly HDL-2 cholesterol.* 39

Grape Seed Extract

A source of free-radical scavenging phytonutrients, known as polyphenols.* Promotes healthy circulation.* Also supports cardiovascular health by increasing HDL cholesterol levels*40,41

N-Acetyl-L-Cysteine (NAC)

A derivative of the amino acid, cysteine, NAC is a key intermediary in the conversion of cysteine into glutathione, one of the body’s primary cellular antioxidants.* Supports the health of the cardiovascular and immune systems.* Also shown to significantly increase in HDL cholesterol.*42

Alpha Lipoic Acid (ALA)

An antioxidant and vital cofactor necessary for the production of cellular energy, ALA helps recycle other important antioxidants, including vitamins C and E, CoQ10, and glutathione. Also helps maintain healthy blood flow and healthy heart contraction.*43

Soy Isoflavones

Provide antioxidant protection, supporting cardiovascular and immune system health.* Soy protein-enriched diet has been shown

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Ola Loa Multi-Vitamin Mineral Formula
TopPreviousNext

Date: February 22, 2006 06:33 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ola Loa Multi-Vitamin Mineral Formula

Ola Loa

Lets face it. Most people don’t look forward to taking their daily vitamins. Its too complicated; there are too many pills and capsules. You take some with food, some with out. Forget to eat this morning? Put your pills in your pocket and carry them with you to take at lunch or dinner or tomorrow?

With Ola Loa’s single serving packs, getting your daily multi is not only convenient and delicious, but also based on sound nutrition science. That’s the Ola Loa Advantage!

In formulating Ola Loa, Richard Kunin M.D. chose its powerful combination of vitamins, minerals and amino acids based on their functional uses in the body and his 40 years of scientific research and experience giving nutrients to his patients. Nowhere will you find a more strategic and effective collection of nutrients.

Ola Loa Energy formula includes NAC, and Vitamin C (which strengthens antioxidant and immune function), along with six amino acids, CoQ10, and 40 mineral complexes. Ola Loa provides you with enough TMG to lower homocysteine and raise SAME levels. Ola Loa’s nutrients and pleasing taste have almost instant benefits. You will feel a difference.

Ola Loa REPAIR is a great tasting effervescent multi-vitamin powder that provides unparalleled nutrient support for bones, joints, cartilage and the aches and pains of everyday life. REPAIR is recommended for daily bone and joint health, as a general anti-aging vitamin and is a comfort to those concerned about bone health and regular wear-and-tear on joints.

Our convenient grab-and-go packs are easy to bring with you wherever you go. Just pack Ola Loa for your business or pleasure trips or throw a few packets in your brief case, purse or desk drawer. Having Ola Loa around encourages regular vitamin consumption and will give you that boost of nutrients whenever, wherever you need it.



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High Absorption CoQ10
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Date: February 13, 2006 05:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: High Absorption CoQ10

The human heart beats more than two and a half billion times in an average lifetime. The energy required for this miracle of nature is enormous, and maintaining heart tissue energy levels is essential. A vitamin-like nutrient found in the human body, Coenzyme Q10 or CoQ10 supports heart function. Without adequate CoQ10, cells become energy-deficient. When nourished with optimal levels of CoQ10, your body tissues, including the liver, nerves and muscles function optimally. With its high energy requirements, the heart needs to be supplied with CoQ10 at all times. Numerous clinical studies have shown significant improvements in heart function with oral administration of CoQ10. Immune cells need large amounts of energy, and CoQ10 helps make it available. A versatile antioxidant, it stabilizes membranes and protects them from free-radical damage. A fat-soluble nutrient, CoQ10 is difficult to absorb, so we’ve added Bioperine. Preliminary Trails on humans have shown significant increases in absorption of Bioperine-enhanced nutrients. High absorption CoQ10, a pharmaceutical grade supplement, is now available in three different forms: 30mg/60 caps; 100mg/30 caps; and 100mg/60 caps. High Absorption CoQ10 with bioperine


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Molecularly Distilled Omega-3 fish Oil Fact Sheet
TopPreviousNext

Date: January 12, 2006 03:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Molecularly Distilled Omega-3 fish Oil Fact Sheet

Molecularly Distilled Omega-3 fish Oil Fact Sheet

Neil E. Levin, CCN, DANLA 10/26/04

LIKELY USERS: Everyone consuming fast foods or diets high in vegetable oils; People with family history of heart disease or diabetes; People with inflammatory conditions

KEY INGREDIENT(S): Molecularly distilled fish oil concentrate

MAIN PRODUCT FEATURES:
  • Cholesterol free
  • Natural lemon flavor
  • This oil is easier for many people to tolerate than other fish oils
  • Antioxidant blend of Rosemary Extract, Ascorbyl Palmitate and Natural Tocopherols
  • Natural triglyceride form (unlike some other brands using the ester form)
  • Manufactured and distilled in a pharmaceutical facility in Norway according to pharmaceutical protocols
  • Molecularly distilled and screened for the absence of potentially harmful levels of contaminants (i.e. mercury, heavy metals, PCB's, dioxins, etc.)
  • Derived from open sea catches of sardines and anchovies
  • Also available in unflavored enteric-coated capsules
OTHER IMPORTANT ISSUES:
 
  • Molecular distillation removes impurities such as pesticides (PCBs, PCDFs, PCDDs, Dioxin) and heavy metals (mercury, lead)
  • Exceeds contaminant safety standards per CRN monograph and California state law
  • No trans-fats
  • Consumption of Omega-3 fatty acids may reduce the risk of coronary heart disease. (FDA evaluated the data and determined that, although there is scientific evidence supporting the claim, the evidence is not conclusive.)
  • Helps control triglycerides and prevent excessive clotting>
  • Promotes anti-inflammatory prostaglandins that also encourage dilation of blood vessels
  • Essential for brain, nerves, cell membranes and blood sugar metabolism
  • Aids in maintaining normal heart rhythm

    AMOUNT TO USE: One teaspoon a day provides 740 mg. of EPA and 475 mg. of DHA. Use one or more teaspoons per day.

    SYNERGISTS: Other supplements used as cardiotonics include Vitamin E, CoQ10, magnesium, antioxidants, garlic, ginger, cayenne pepper, L-carnitine and hawthorn leaf and flower extract.

    CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. But no cautions have been noted to date for pregnant or nursing women using fish oils, which are often recommended for pregnant and nursing women.

    Disclaimer:  These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.




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    Effer-C NUTRITION YOU CAN DRINK
    TopPreviousNext

    Date: December 27, 2005 09:49 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Effer-C NUTRITION YOU CAN DRINK

    Effer-C NUTRITION YOU CAN DRINK

    • 1000 mg of Vitamin C Per Serving
    • Helps Restore Vital Electrolytes
    • Includes CoQ10 and Alpha Lipoic Acid
    • High in Energy-Producing B Vitamins
    • 4 Great Tasting Flavors

    Vitamin C (ascorbic acid) is unquestionably one of life’s most important nutrients. Everyday we unknowing rely on it to help protect cells, produce energy, repair tissue and replenish lost electrolytes. Ironically, humans are just one of a handful of living creatures unable to produce our own supply of this vital nutrient. In fact, your dog can naturally manufacture upwards of ten times the amount of vitamin C that you might obtain in an entire day from food.

    To make matters worse, vitamin C can be a terribly stubborn nutrient. Not only are we incapable of producing it, but getting adequate amounts from the diet is a task all in itself. Today’s typical diet has become just that, typical. The convenience of fast food, sodium-rich snacks and over-processed heart bombs has reduced our once healthy society to a scrambling cluster of time-pressed professionals who’ve somehow forgotten what it’s like to actually prepare balanced, nutritious meals. This makes obtaining the nutrients we so desperately need, next to impossible.

    As if that wasn’t enough, vitamin C has a short halflife. Half lives measure the amount of time that it takes for one-half of a nutrient to be depleted from the bloodstream. In the case of vitamin C, it has a half life of just 30 minutes. For the sake of argument, let’s assume that your 7:00 AM breakfast includes an orange that contains a modest 70 mg of vitamin C. By 8:00, you’re left with only 35 mg. By 9:00, a mere 17 mg. And by the time lunch rolls around, you’ll be lucky to have any vitamin C in your system at all. This should be of great concern to anyone who doesn’t carry a bushel of oranges around at all times. Because aside from the fact that the body rapidly depletes its reserve of vitamin C, it also depends on what remains to carry out an long list of biological tasks. When it’s not there, everything suffers - energy, metabolism, immune response, cartilage integrity and so on.

    So how does one contend with this taxing concoction of unceasing stress, high-throttle lifestyle, endless toxins and pathetic dietary habits? It’s actually much simpler than you might imagine. Thanks to new technology in the nutritional sciences, getting the C you need no longer requires carrying around bottles of capsules or huge sacks of fruit. Effer-C™ from NOW® is an effervescent vitamin C unlike any other, and was designed to quickly replenish the vital electrolytes needed to keep you running strong. With a nutritional profile superior to other fizzy C drinks, a taste that won hands-down in blind tests and an exceptional grade of ascorbic acid, Effer-C™ is clearly the smart choice.

    Vitamin C

    Starting with a exceptional grade of Vitamin C was the first step in formulating this superior drink. Fueled by 1000 mg of highly absorbable, gentle vitamin C, you can be assured that you’re getting enough C to keep you tip-top for hours. By utilizing a buffered, non-acidic vitamin C, Effer-C™ offers fast assimilation to boost energy and restore vital electrolytes without causing gastric irritation.

    B-Complex

    Busy lifestyles rob you of so much more than just time. Physical stress and mental anxiety can drain even the healthiest individuals of energy producing, mood supporting B vitamins. As these reserves diminish, so does the ability to stay motivated, focused, patient, responsive and energetic. Effer-C™ is bursting with a full B profile that contains as much as two times the amount of certain B-vitamins found in other brands.

    Calcium/Magnesium

    Calcium and magnesium have become synonymous with strong, healthy bones. Aside from their structural supporting properties, these two minerals work synergistically to help support the body’s adenosine triphosphate (ATP) energy reserves. Individually, magnesium is present in virtually every human biological process. Many of today’s most common elements (alcohol, fluoride, processed foods) can hinder your ability to retain optimal levels of this vital nutrient. Effer-C™ brings them right back!

    Chromium

    This essential trace mineral is a primary component in the synthesis of fats, carbohydrates and proteins. Chromium also has a direct influence on the efficacy of our metabolism, in addition to how well we use glucose. Even a slight deficiency in chromium can result in fatigue, anxiety and glucose intolerance. Effer-C™ contains 20 mcg of chromium - more than even the most popular effervescent C supplement.

    Anti-oxidants

    Part of what makes Effer-C™ so effective is its unique antioxidant profile. By adding more alpha lipoic acid (ALA) than similar competing products, in addition to 5 mg of CoQ10 and zinc, Effer-C™ provides powerful protection against harmful, cell damaging free radicals. If you haven’t experienced the nutritional rush that Effer-C™ delivers, you don’t know what you’re missing. NOW makes it easier than ever to stay energized and fully replenished throughout the day, during workouts and even on the road. Available in four delicious flavors (orange, lemonlime, raspberry and cranberry Effer-C™ is a simple and effective way to maintain high levels of vitamin C and unlock the energy that’s just waiting within.

    EFFER-C RASPBERRY from NOW EFFER-C LEMON LIME from NOW EFFER-C CRANBERRY from NOW EFFER-C ORANGE from NOW



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    Your Cells Supercharge Your Cells
    TopPreviousNext

    Date: December 20, 2005 11:30 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Your Cells Supercharge Your Cells

    Your Cells Supercharge Your Cells

    The differences between aging and growing old are poles apart. Sure, they may sound similar in nature. But when you think about it, the two are as different as night and day. Growing old is about retirement and travel and enjoying what you’ve worked an entire life for. Aging, on the other hand, summons images of wrinkled skin, brittle joints, cloudy minds and medicine cabinets full of prescriptions. It’s safe to assume that the majority of us want to look, live, and feel better as we grow old. Not the opposite. Many of us are on the right track - committed to a healthy lifestyle that includes regular exercise and a well-balanced diet. And yes, these do serve as a solid foundation for good health during our golden years. It is our cells, however, that ultimately determine who grows old, and who just ages.

    Still, slowing the proverbial hands of time is not all about health clubs and organic produce. If you want to grow old gracefully, you must nurture the ten trillion cells that defi ne you physically. Why? Because these cells are constantly under attack by free radicals - unstable molecules that either lack, or have an unpaired number of electrons. They scour the body in search of stable cells, and do whatever they can to rob them of their electrons, a process more formally known as oxidation. Considering that it’s environmentally impossible to completely avoid contact with the billions of airborne toxins that cause free radicals, the only other option is to safeguard your healthy cells. Making the commitment to a healthy lifestyle is the fi rst step in the process, and can be accomplished by eating healthier foods, exercising on a regular basis, and paying close attention to what you are exposed to environmentally.

    The next step is to nourish and protect your cells. The best way to do this is to consume foods that are rich in antioxidants and other cell-friendly nutrients. Unfortunately, this task is often much easier said than done. Today’s average adult is busier than ever, making it far more diffi cult to consume fresh, unprocessed meals 100% of the time. This does not, however, imply that all hope is lost. Over the years, the nutritional sciences have made stunning advances that afford you the opportunity to live your life while still safeguarding the integrity of your most basic building blocks. Here are a few of the best.

    Antioxidants

    Antioxidants work at the cellular level to paralyze the free radicals that cause oxidation throughout the body. Some of today’s most popular nutrients and dietary supplements fall into this category. They include vitamins A, E, and C, Selenium, Zinc, Alpha Lipoic Acid, Lycopene, Lutein, CoQ10, in addition to a host of others. And though similar in function, each of these free radical fi ghters has a unique role within the body.

    Take CoQ10 for example. It’s present in every cell of the body, and is especially important for cardiovascular support. Lutein has been used extensively to prevent oxidation in the macular regions of the eyes. Zinc is a powerful immune system booster that has become extremely popular during cold and fl u season. Alpha Lipoic Acid is both fat and water soluble, and is commonly referred to as the “universal” antioxidant based on its ability to quench free radicals anywhere in the body.

    Immune Boosting Herbs

    Herbs such as Astragalus, Olive Leaf, Rhodiola, Echinacea, Panax Ginseng and Ashwaganda have been used for centuries to help support healthy cells and strong, responsive immune systems. They’ve also been shown to exhibit natural synergistic effects when used together. Today, they remain one of the most popular ways to naturally promote all-around wellbeing. When it comes to supporting healthy cells, NOW is pleased to offer one of the best selections of antioxidants, herbs and immune support formulas. Be sure to look for these and other great products at fi ne health food retailers, nationwide.*

    OPCs

    OPCs (proanthocyanidins) are high-powered polyphenol antioxidants that belong to the fl avonoid family. Grape seed extract, pine bark extracts such as pycnogenol and enzogenol, bilberry, gingko biloba, resveratrol and others all fall into this category. Research continues to suggest that OPCs work in the same manner that traditional antioxidants do, however their ability to eradicate free radicals is much greater and more versatile. Equally appealing, OPCs can easily cross the blood barrier of the brain to help protect brain and neural tissues from the damage caused by oxidative stress.

    Mushroom Extracts

    Throughout history, many civilizations have relied on organic mushroom extracts to encourage wellness. What we know now is that mushrooms such as Shiitake, Maitake, Reishi and others are rich in 1,3 Beta-glucans - soluble fi ber compounds that help support both innate and adaptive immunity. In addition, the active compounds in some mushrooms have been shown to stimulate the production of microphages, T cells, and other natural killer cells. These biological warriors serve at the front line when it comes to responding to bacterial attacks. They are of immeasurable value to the immune system, though drastically lacking in today’s average diet. In just the past few years, more and more healthconscious individuals have learned fi rst-hand how benefi cial they can be in the preservation of healthy cells.



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    GliSODin Anti-Aging and Antioxidant Protection
    TopPreviousNext

    Date: December 19, 2005 08:47 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GliSODin Anti-Aging and Antioxidant Protection

    GliSODin Anti-Aging and Antioxidant Protection

    • Superior Anti-Aging Formula
    • Stimulates Natural Antioxidant Defenses
    • Helps Protect DNA
    • Reduces Oxidative Stress
    • Prevents Oxygen Related Cell Damage

    In the time it takes you to finish reading this article, you, your body and your cells will have aged. Some, more than others. Nevertheless, every second that ticks away should serve as a reminder that our time here is temporary. How much time we actually end up with depends on many things. Diet. Lifestyle. Environment. Superoxide Dismutase? I’ll explain. What some of the healthiest individuals fail to realize is that our bodies age from the inside out. Aging is not the result of passing time, but rather the result of what we’re exposed to environmentally, physically and chemically. It is the integrity of our cells, not our clocks, that determine how smooth the aging process fares.

    Each day, we’re subjected to millions of elements that affect us in ways seldom seen, felt or noticed. From the moment we’re born, we rely on our cells to work around the clock - producing energy, fighting infections and sustaining life. These same cells eventually determine the rate at which we show (or hide) our age.

    Taking into consideration that our planet has no shortage of toxins & germs, the need to safeguard our cells becomes very real. Constant exposure to exhaust, secondhand smoke, heavy metals, lead, fluoride and uncountable other noxious compounds should ideally provide us with nothing more than a routine immune system workout. Unfortunately, over long periods they hinder our “resistance” abilities and become stepping stones to accelerated aging.

    Antioxidants. We’ve all heard the term before, and may even have a general understanding of their role. But to better grasp just how vital they are, it helps to know what’s happening at the cellular level. Free radicals are unstable molecular thieves that often lack electrons. To compensate, they rob healthy cells - a process better known as oxidation. Antioxidants work with the immune system to prevent oxidation, and clean up the mess it leaves behind. Hence, the name.

    There are two types. Exogenous antioxidants are derived from our diet and include vitamins A, E, and C along with others such as alpha lipoic acid, selenium, CoQ10, grape seed, pycnogenol and zinc. To date, we’ve been limited to exogenous antioxidants as a way to increase the rate at which our body wards off oxidation. They are not, however, our first line of defense. At birth, each and every one of us is equipped with three primary endogenous enzymatic antioxidants; SOD (Superoxide Dismutase), Glutathione Peroxidase (GPx) and Catalase.

    While both types of antioxidants are beneficial, we’ve become reliant on those from the diet to compensate for our inability to boost the effectiveness of our 3 primary antioxidants. For years, researchers have been examining ways to enhance the activity of our built-in bodyguards. One in particular, Superoxide Dismutase (SOD) has been of foremost interest. SOD targets what many researchers regard as one of our greatest health threats and aging accelerators - Superoxide radicals. These highly reactive, merciless molecules incite enormous amounts of oxidative stress and are capable of wreaking havoc on healthy cells. When cells are left unprotected by SOD, the results can be disastrous - respiratory problems, premature aging, memory loss, cardiovascular challenges, vision failure and joint structure damage, among others.

    Until now, we’ve been at the mercy of our natural SOD reserves to fight superoxides. Researchers have been working feverishly to produce an effective oral SOD supplement, but have continually encountered a frustrating hurdle - exposure to gastric acid denatures SOD, rendering it useless. As a result, the only effective way to supplement SOD was through injections. These, however, only yielded short-term spikes. And then something remarkable happened that changed everything. Nutrition scientists in France determined that by combining Cucumus melo (a melon high in SOD) with a wheat gliadin stabilizer, it would be possible to prevent SOD from deteriorating in the digestive tract, while preserving it in the blood for extended periods. Not only is this the answer to a puzzle that has plagued researchers, it’s a breakthrough that will impact the life of anyone seeking longevity and vitality.

    As the first proven oral SOD supplement ever introduced to the public, GliSODin® has taken antioxidant protection, immune support and antiaging science to an entirely new level. The primary function of GliSODin® is to scour the body for superoxide radicals and reduce them to less reactive ions that can be swept away; a process known as dismutation. In addition, GliSODin® reduces the oxidation vulnerability of healthy cells, protects mitochondrial activity and safeguards DNA structure.

    What’s most remarkable is that GliSODin® has actually been shown to stimulate the body’s own natural production of all three enzymatic antioxidants, including SOD. For the first time in history, we will have the ability to enhance the effectiveness of our body’s primary defense mechanism.

    New GliSODin® from NOW® represents the ultimate in antioxidant protection. By increasing one’s level of SOD while stimulating the natural production of Glutathione Peroxidase and Catalase, GliSODin® delivers antioxidant protection unlike any previously released dietary supplement. Remember, the aging process begins at a level that we simply can not see, the cellular level. Shielding your cells from superoxide damage is one of the smartest steps you can take against aging before your due time. GliSODin® has made this a reality.



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    The Free Radical Theory
    TopPreviousNext

    Date: December 14, 2005 12:11 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: The Free Radical Theory

    The popular theory has been the subject of a great deal of research. Developed by Denham Harman, M.D., Ph.D., at the University of Nebraska in 1956, the free radical theory proposes that unstable molecules known as free radicals are responsible for inflicting extensive cellular damage, which causes cell death and dysfunction and eventually, disease. The most common type of free radicals are oxygen derived, and free radical damage is often referred to as oxidation.

    Environmental sources of free radicals include radiation (I.E., sun exposure, X-rays), ozone and nitrous oxide, heavy metals (i.e., mercury, cadmium, lead), smoke, alcohol, saturated fat, and other chemicals and pollutants. The body itself generates free radicals in performing essential bodily functions including energy production and immune activities. Fortunately, the body also has the ability to create antioxidants to neutralize the free radicals and prevent extensive cellular damage. When free radicals are not neutralized by antioxidants, they inflict large-scale cellular damage which can cascade and lead to age-related degenerative diseases such as osteoarthritis, osteoporosis and age –relaged macular degeneration. For example, free radical damage to joint cells may cause the cartilage to become rough or break down, and can lead to the development of osteoarthritis. Antioxidants are needed to comb at free radicals and prevent this cellular damage. “Oxidative stress can lead to DNA mutations, cell death, and disease, all of which contribute to aging,” said Gerald R. Cysewski, president and chief executive officer (CEO) at Cyanotech corp. “Antioxidants are produced naturally by the body to combat oxidative stress by neutralizing free radicals. Increasing the amount of antioxidants in one’s system by consumption of supplements can provide further protection from the damaging effects of free radicals.”

    Because the body is continually assaulted by free radicals, antioxidant supplementation is often necessary. “by taking certain nutrients that our bodies stop producing over time, supplements help us to maintain a youthful look and health, which in turn enhances the quality of life,” Alkayali said. “Furthermore, supplements can help decrease oxidative stress that may otherwise accompany age-related illness and disease.”

    Many Substances are known antioxidants including certain enzymes, vitamins, phytochemicals and minerals, and include Vitamin C, Vitamin E, alpha-lipoic acid, coenzyme Q10 (CoQ10), Carotenoids, Selenium, superoxide dismutase, melatonin, quercetin, catechins, and zinc.

    Consuming a diet high in plant sources of powerful antioxidants is an important step to deter ageing, because nutrients from foods are often highly bioavailable and can act synergistically to increase their health benefits. Garlic contains several antioxidant phytochemicals and minerals including allicin, beta-carotene, quercetin, selenium and zinc, and may have a protective effect against stomach and colorectal cancers.

    Catechins are potent antioxidants flavonoids, with the best known source being green tea; they include gallocatechin (GC), epigallocatechin (EGC), epicatechin (EC) and epigallocatechin gallate (EGCG). These antioxidants are being studied for their powerful abilities to combat free radical damage. In particular, EGCG has been researched for its reported protection against certain cancers and Alzheimer’s disease.

    Green Foods such as seaweed, sea vegetables, young grain grasses and shoots, broccoli, cabbage and other green leafy vegetables pack a nutritional punch due to their concentratged amounts of antioxidant carotenoids, vitamins and the enzyme superoxide dismutase (SOD). SOD is produced by the body and neutralizes free radicals known as superoxide radicals, which cause damaging fat oxidation. GliSODin is a patented form of SOD derived from cantaloupe and bound to a wheat protein for superior bioavailability. “GliSODin promotes the body’s production of its own endogenous antioxidants, including SOD, catalase and glutathione peroxidase, in virtually every cell,” said Eric Anderson, brand manager at P.L. Thomas. “This activation of the cellular antioxidant defenses across the whole body creates a state of alertness against any shock of oxidative stress, including sun rays, to which our body may be exposed.”

    Pomegranates contain two powerful antioxidants—ellagic acid, derived from fruit’s seeds, and punicaligans, found in the juice. “Research has shown that the juice from the pomegranate, rich in polyphenols, reduces oxidative stress by helping to produce enzymes to fight free radicals,” Alkayali said. NeoCell Corp. manufactures of ellagic-acid based Pomegranate Power, while P.L. Thomas supplies POM40p, a kosher-free pomegranate juice extract standardized to 40-precent punicocides, polyphenols belong to the punicalagin family.

    Consumer demand is on the rise for products that address degenerative health conditions, including supplements that support function of the bones, joints, eyes. According to a June 2005 report by the freedonia group, “Bone and joint care products will continue to dominate the health maintenance segment, spurred by a growing customer base and a plethora of new and improved products expected to soon enter the marketplace.” The report also projected rapid gains for vision care. “Demand for vision care products will be propelled by aging baby boomers who are becoming aware of debilitating eye conditions and seeking both preventive measures and ameliorative treatments.” Dietary Supplements can help prevent and ease symptoms of age-related diseases affecting the joints, bones and eyes, including osteoarthritis, osteoporosis and age-related macular degeneration (AMD).



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    Coenzyme Q10 and Cardiovascular Health.
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    Date: December 13, 2005 11:34 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Coenzyme Q10 and Cardiovascular Health.

    CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function!

    CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body.

    CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits.

    As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.”

    “The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication.

    Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.



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    Tru-E Bio Complex
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    Date: December 08, 2005 04:58 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Tru-E Bio Complex

    Tru-E Bio Complex TM

    Neil E. Levin, CCN, DANLA 7/27/05

    LIKELY USERS: Most Americans are deficient in Vitamin E 8,9,10; People needing superior antioxidant protection3,5,6; People needing cardiovascular or cholesterol support27,30,31; People needing nervous system support7; Those wanting healthier skin6; Diabetics may need additional Vitamin E24 KEY INGREDIENTS: Tocopherols from IP-Preserved, non-GMO Soy; Tocotrienols and tocopherols from non-GMO virgin palm; Tocotrienols from non-GMO annatto seed

    MAIN PRODUCT FEATURES: NOW Tru-E Bio ComplexTM is a unique biologically balanced, patent-pending formula designed to provide optimal Vitamin E activity. This product features 100% natural, Non-Genetically Modified sources of all 8 isomers (forms) of the Vitamin E “family” in ratios similar to what is found in a healthy diet. It provides the superior benefits of foodsource Vitamin E versus those obtained from traditional E supplements.

    NOW® Tru-E Bio ComplexTM has been carefully blended to supply high levels of the natural gamma and delta “desmethyl” forms of both tocopherols and tocotrienols. This is important because recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues. This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants. This science-based natural Vitamin E supplement is unlike any other and the first to combine all of these benefits in one convenient non-GMO formula! 25-32

    Recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues.1-4, 25-32

    This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants.1,4-7

    Levels of Vitamin E above 100 IU daily are associated with decreased risk of coronary heart disease and certain types of cellular disorders, as well as enhancement of immune function. These vitamin E intakes are considerably above levels obtainable from diet alone. 11,12,13

    ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

    This is a product that is Patent Pending, based on months of research into optimal forms, potencies and ratios of the 8 isomers of natural Vitamin E. All of the Vitamin E formulas currently on the market use potencies of tocopherols that are very dissimilar to what is found in a healthy diet, with either too low or too high amounts of gamma and alpha tocopherols for a good balance. Some do not even include tocotrienols.

    All of the Vitamin E formulas on the market that do contain a mixture of tocopherols and tocotrienols tend to use either 400 IU or 100 IU of alpha tocopherol, some as little as 50-60 IU, combined with varying doses of gamma tocopherol. We have reduced the alpha tocopherol from the standard 400 IU per capsule to 200 IU, allowing more gamma tocopherol in the capsule to follow the typical ratio in a healthy diet. Other brands either cut the alpha tocopherol too low (to keep the gamma tocopherol at a good level) or else cut the gamma and other tocopherols too low (to keep the alpha tocopherol at 400 IU).

    Special care was used to maintain a certain ratio of tocopherols and of tocotrienols that is unique and from natural sources. Our formula is also unique in mixing sources of tocotrienols to achieve our desired balance, whereas other formulas include only one source, despite the dissimilarity of the mixture to what is found in a healthy, varied diet.

    Other formulas use either Vitamin E derived from genetically engineered soybeans and/or add soybean oil from similar sources as a base. NOW uses expensive non-GMO sources, the first formula to do so, with no soybean oil added. This enhances the quality of our product compared to every other formula on the market.

    We use the expensive virgin palm oil rather than the cheap palm distillates because it is un-denatured and contributes additional, valuable oil nutrients such as CoQ10, Squalene and Sterols. Also, much of the clinical research done on tocotrienols was done using virgin palm oil sources 32

    Natural Vitamin E is more effective than synthetic Vitamin E.14 - 23

    SERVING SIZE & HOW TO TAKE IT: One or two capsules per day, preferably with meal(s). Oils enhance the absorption of Vitamin E. Concentrated fiber supplements may decrease the absorption of Vitamin E, so it is best not to take both at the same meal.

    SYNERGISTS: Antioxidants (Alpha Lipoic Acid, Vitamin C Complex, Pine or Grapeseed Extracts, VitaBerry Plus+, CoQ10, etc.), Plant Sterols, Fish Oil, Flaxseed Oil, GliSODin, EGCg Green Tea Extract, Lecithin, Nuts and Seeds

    CAUTIONS: None.

    SPECIFIC: Aspirin and blood thinners should not be taken with Vitamin E without physician’s approval. Many other pharmaceutical drugs deplete Vitamin E, adding to the likelihood that a person will be deficient.

    GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

    REFERENCES:

    1. Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) g-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74:714-722.
    2. Schneider C (2005) Chemistry and biology of vitamin E. Mol Nutr Food Res 49(1):7-30.
    3. Pfluger P, Kluth D, Landes N, Bumke-Vogt C, Brigelius-Flohe R (2004) Vitamin E: underestimated as an antioxidant. Redox Rep 9(5):249-254.
    4. Liu M, Wallin R, Saldeen (2002) Effect of mixed tocopherols on ecNOS, SOD, and PKC in leukocytes in human subjects. Nutr Res 22:1253-1263.
    5. Saldeen T, Li D, Mehta JL (1999) Differential Effects of a- and g-Tocopherol on Low-Density Lipoprotein Oxidation, Superoxide Activity, Platelet Aggregation and Arterial Thrombogenesis. J Am Coll Cardiol 34:1208-1215.
    6. "Packer L, Valacchi G. (2002) Antioxidants and the response of skin to oxidative stress: vitamin E as a key indicator. Skin Pharmacol Appl Skin Physiol 15(5):282-90."
    7. Sen CK, Khanna S, Roy S. (2004) Tocotrienol: the natural vitamin E to defend the nervous system? Ann N Y Acad Sci 1031:127-42.
    8. Dial S, Eitenmiller RR. 1995. Tocopherols and tocotrienols in key foods in the U.S. diet. In: Ong ASH, Niki E, Packer L, eds. Nutrition, Lipids, Health, and Disease. Champaign, IL: AOCS Press. Pp. 327–342.
    9. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000). Institute of Medicine
    10. JASPREET K.C. AHUJA, JOSEPH D. GOLDMAN, and ALANNA J. MOSHFEGH. Current Status of Vitamin E Nutriture. Ann NY Acad Sci 2004 1031: 387-390.
    11. Bauernfeind, J. Tocopherols in Foods. In: Vitamin E: A Comprehensive Treatise. Marcel Dekker, Inc., New York and Basel, pp. 99-167, 1980.
    12. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
    13. Weber, P., Bendich, A. and Machlin, L.J. Vitamin E and Human Health: Rationale for Determining Recommended Intake Levels. Nutrition 13:450-460, 1997.
    14. Acuff RV et al. Am. J. Clin. Nutr. 1998;67:459-64
    15. Acuff RV et al, Am. J. Clin. Nutr. 1994, 60:397-402
    16. Behrens, W.A. and Madere, R. Tissue Discrimination between Dietary RRR-Alpha- and All-Rac-Alpha-Tocopherols in Rats. J. Nutr. 121:454-459, 1991.
    17. Burton G et al, Am. J. Clin. Nutr. 1998,67:669-84
    18. Ferslew, K.E., Acuff, R.V., Daigneault, E.A., Woolley, T.W. and Stanton, P.E. Pharmacokinetics and Bioavailability of the RRR and All Racemic Stereoisomers of Alpha-Tocopherol in Humans after Single Oral Administration. J. Clin. Pharmacol. 33:84-88, 1993.
    19. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
    20. Ogihara, T., Nishida, Y., Miki, M. and Mino, M. Comparative Changes in Plasma and RBC Alpha-Tocopherol after Administration of dl-Alpha-Tocopheryl Acetate and d-Alpha-Tocopherol. J. Nutr. Sci. Vitaminol. 31:169-177, 1985.
    21. Traber M et al, FEBS Letters 1998,437:145-148
    22. Traber MG, et al. J Lipid Res. 1990,31(4):675-85
    23. Weiser, H. and Vecchi, M. Stereoisomers of Alpha-Tocopheryl Acetate. II. Biopotencies of All Eight Stereoisomers, Individually or in Mixtures, as Determined by Rat Resorption-Gestation Tests. Internat. J. Vit. Nutr. Res. 52:351-370, 1982.
    24. Polidori MC, Mecocci P, Stahl W, et al. Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diabetes Metab Res Rev 2000;16:15–9.
    25. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, and Mordan LJ. gamma-Tocopherol Detoxification of Nitrogen Dioxide: Superiority to alpha-Tocopherol. PNAS 1993; 90: 1771-1775.
    26. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr. 2005 Feb;81(2):508-14. PMID: 15699242
    27. Inokuchi H, Hirokane H, Tsuzuki T, Nakagawa K, Igarashi M, Miyazawa T. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317
    28. Kline K, Yu w, Sander BG, et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. (1999), Nutr Cancer, 33 : pp : 26 – 32
    29. The Chicago Health and Aging Project, Martha Clare Morris, Denis A Evans, Christine C Tangney, Julia L Bienias, Robert S Wilson, Neelum T Aggarwal and Paul A Scherr. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. American Journal of Clinical Nutrition, Vol. 81, No. 2, 508-514, February 2005
    30. Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388
    31. Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Hypocholesterolemic activity of synthetic and natural tocotrienols. J Med Chem. 1992 Oct 2;35(20):3595-606. PMID: 1433170
    32. Soelaiman IN, Ahmad NS, Khalid BA. Palm oil tocotrienol mixture is better than alpha-tocopherol acetate in protecting bones against free-radical induced elevation of bone-resorbing cytokines. Asia Pac J Clin Nutr. 2004 Aug;13(Suppl):



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    Co-Enzyme B-Complex Fact Sheet
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    Date: December 08, 2005 04:40 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Co-Enzyme B-Complex Fact Sheet

    Co-Enzyme B-Complex Fact Sheet

    Neil E. Levin, CCN, DANLA 8/1/05

    LIKELY USERS: People with poor digestion or low stomach acid, People needing ENERGY, People desiring metabolism support.

    KEY INGREDIENTS: CoEnzyme B-Vitamins plus synergists

    MAIN PRODUCT FEATURES: B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as cofactors in biochemical reactions. NOWR Co-Enzyme B-Complex contains B Vitamins already in their active or "Coenzyme" forms. This enables the body to use them more quickly and efficiently because, once absorbed, they are transported directly to their site of action, requiring no conversion. 1

    B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes 1, 2. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as coenzymes in biochemical reactions 1, 2.

    ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOWR Co-Enzyme B-Complex tablets are enteric coated to enhance bioavailability by allowing delivery to intestinal absorption sites intact, unharmed by stomach acids.2 Our Quality department had to qualify several new ingredients for this formula.

    This formula is enhanced with added Coenzyme C10 (CoQ10), Alpha Lipoic Acid, Betaine (TMG), Vitamin C, and both coenzyme forms of B-12 (Methylcobalamin and Dibencoside) and is suitable for vegetarians and vegans.

    SERVING SIZE & HOW TO TAKE IT: Two tablets daily, preferably in divided doses. This enteric-coated tablet is best to take between meals (one or more hours before a meal or hours after a meal), as it has an acid-resistant coating that dissolves beyond the stomach and needs to transit quickly past the stomach.

    COMPLEMENTARY PRODUCTS: Vitamin C, TMG (Betaine), Lecithin (Choline, Inositol)

    CAUTIONS: None.

    SPECIFIC: Please discuss your use of B-Vitamins with your physician, especially if you are using any medications.

    GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

    Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

    REFERENCES:

    1. Shils ME, Olson JA, Shike M (eds.) (1994) Modern Nutrition in Health and Disease, Eighth Edition. Chapters 20-26, 28, 30. Lea & Febiger Philadelphia.
    2. Chang EB, Sitrin MD, Black DD (1996) Gastrointestinal, Hepatobiliary, and Nutritional Physiology. Chapter 9, Absorption of Water-Soluble Vitamins and Minerals. Lippincott-Ravin, Philadelpia



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    Carnitine Creatinate
    TopPreviousNext

    Date: December 08, 2005 03:33 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Carnitine Creatinate

    Carnitine Creatinate

    Neil E. Levin, CCN, DANLA 6/30/05

    LIKELY USERS: Athletes, Bodybuilders, Dieters, People who consume a lot of fat, People needing cardiovascular support (energy for the heart), People who need quick energy, especially for fast muscle response, People with muscle wasting problems (including the elderly), Weightlifters

    KEY INGREDIENTS: L-Carnitine and Creatine Monohydrate

    MAIN PRODUCT FEATURES: Carnitine Creatinate Monohydrate is a specialized form of Creatine bonded to L-Carnitine. Creatine is a compound natural to the human body that aids in the regeneration of ATP, the chemical energy used by muscle tissue. During exercise, large quantities of creatine are irreversibly consumed. Clinical studies have shown that oral supplementation with Creatine can increase the amount of Creatine available in muscles for ATP production. L-Carnitine is an amino acid that is necessary for the transfer of fatty acids into the fat-burning parts of the cell, facilitating energy production from fat. The combination of these two compounds can produce a synergistic effect, making NOW® Carnitine Creatinate an ideal energy supplement.

    ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: Carnitine and Creatinate Monohydrate is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product. Protected by U.S. Patent No. 5,994,581 (L-Carnitine Creatinate Monohydrate).

    Look at the price: this is a better way to buy both supplements than purchasing them separately.

    This formula is suitable for vegetarians and is offered in both tablet and powder forms.

    SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every two tablets provide 1,000 mg. (one gram) each of both L-Carnitine and Creatine Monohydrate. Or one teaspoon provides 1,150 mg.) each of both L-Carnitine and Creatine Monohydrate. Take one or more servings per day with a carbohydrate source, such as fruit juice or sports drinks.

    COMPLEMENTARY PRODUCTS: CoQ10, carbohydrates, B-Complex vitamins, chromium, vanadium, Hawthorn leaf and flower extract, protein supplements. Adaptogenic herbs: ginsengs, Eleuthero, Rhodiola, Maca, Ashwaganda, licorice root

    CAUTIONS: none.

    PRODUCT SPECIFIC: This product is very sensitive to moisture. Please keep in the original packaging or in a moisture resistant container. Do not take more than 20 grams per day. Discontinue use if cramps of stomach upset occur, especially if taking large doses. Do not take if kidney disease is present. Do not use large doses of caffeine with creatine, as it may increase the possibility of muscle cramping.

    GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems.

    Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

    Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

    REFERENCES:

    Fang S-M (1998) Carnitine Creatinate. U.S. Patent 5,994,581.

    L-CARNITINE:

    Beers MH, Berkow R (eds). The Merck Manual of Diagnosis and Therapy, 17th ed. Whitehouse Station, NJ: Merck and Co., Inc, 1999, 881-3.

    Broquist HP (1994) Carnitine, in Modern Nutrition in Health and Disease, 8th ed., Shils ME, Olson JA, Shike M (eds.) Lea & Febiger, Philadelphia, pp. 459-465. Casey A, Greenhoff PL (2000) Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance? Am J Clin Nutr 72(suppl):607S-17S. Columbani P, Wenk C, Kunz I, et al. Effect of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double blind crossover field study. Eur J Appl Physiol 1996;73:434-9.

    Dal Negro R, Pomari G, Zoccatelli O, Turco P. L-carnitine and rehabilitative respiratory physiokinesitherapy: metabolic and ventilatory response in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1986;24:453-6.

    Dal Negro R, Turco P, Pomari C, De Conti F. Effects of L-carnitine on physical performance in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1988;26:269-72.

    Del Favero A. Carnitine and gangliosides. Lancet 1988;2:337 [letter].

    Dipalma JR. Carnitine deficiency. Am Fam Physician 1988;38:243–51.

    Digiesi V, Palchetti R, Cantini F. The benefits of L-carnitine in essential arterial hypertension. Minerva Med 1989;80:227-31.

    Giamberardino MA, Dragani L, Valente R, et al. Effects of prolonged L-carnitine administration on delayed muscle pain and CK release after eccentric effort. Int J Sports Med 1996;17:320-4.

    Green RE, Levine AM, Gunning MJ. The effect of L-carnitine supplementation on lean body mass in male amateur body builders. J Am Diet Assoc 1997;(suppl):A-72.

    Harris RC, Soderlund K, Hultman E (1992) Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci 83(3):367-374.

    Kendler BS. Carnitine: an overview of its role in preventive medicine. Prev Med 1986;15:373–90.

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    Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci 1996;91:113-8.

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    Felber S, Skladal D, Wyss M, et al. Oral creatine supplementation in Duchenne muscular dystrophy: a clinical and 31P magnetic resonance spectroscopy study. Neurol Res 2000;22:145-50.

    Feldman EB. Creatine: a dietary supplement and ergogenic aid. Nutr Rev 1999;57:45–50.

    Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in man. Am J Physiol 1996;271:E821–6.

    Green AL, Simpson EJ, Littlewood JJ, et al. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. Acta Physiol Scand 1996;158:195-202.

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    Stout JR, Eckerson J, Noonan D, et al. The effects of a supplement designed to augment creatine uptake on exercise performance and fat-free mass in football players. Med Sci Sports Exerc 1997;29:S251.

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    Skin Eternal #1 Skin Care Line – Source Naturals
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    Date: November 04, 2005 09:16 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Skin Eternal #1 Skin Care Line – Source Naturals

    Skin Eternal #1 Skin Care Line – Source Naturals

    November is National Skin Health Month! It’s also a time of year when exposure to stormy winter weather and overheated rooms can play havoc with skin. Source Naturals #1 Skin Eternal line can help nourish and recondition dry, chapped and irritated skin.

    Source Naturals Skin Eternal skin care products in Whole Foods magazines annual Natural Choice Awards for two years in a row!

    Skin Eternal products enhance skin tissue with breakthrough ingredients that go deep to the cellular level to recharge and revitalize delicate skin. These include alpha lipoic acid, CoQ10, vitamin C ester, DMAE, plus a wide variety of nutrients and plant extracts. This premier line includes luxurious cosmetic products as well as supplements that support healthy skin from the inside out.



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    Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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    ENADA® NADH 5mg - NEW PRODUCT ANNOUNCEMENT
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    Date: August 03, 2005 05:23 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: ENADA® NADH 5mg - NEW PRODUCT ANNOUNCEMENT

    NEW PRODUCT ANNOUNCEMENT

    ENADA® NADH 5mg

    Energy-Rich Coenzyme—Convenient 60-tab Size!

  • •Essential for the production of ATP, the primary energy carrier in our cells.
  • •The brain, nerves, muscles and heart require a constant supply of ATP energy in order to function.
  • •NADH regenerates the powerful antioxidants CoQ10 and alpha-lipoic acid.
  • •Source Naturals uses ENADA®, the only patented, stabilized, absorbable form of NADH available.

    1 tablet contains:
    NADH (Reduced ß-Nicotinamide Adenine Dinucleotide) 5 mg

    Suggested Use: 1 tablet daily in the morning, on an empty stomach, with water. Wait 30 minutes before eating. Or, take as recommended by your health care professional.



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