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NSAIDs vs. Curcumin: Which One Relieves Joint Pain Without Stopping Healing?   
Date:
September 14, 2026 11:22 AM
Comparative Analysis of NSAIDs versus Curcumin in Musculoskeletal Tissue RepairPrimary Biological Mechanisms and Pharmacological TargetsManaging soft tissue and joint injuries presents a persistent therapeutic challenge in musculoskeletal medicine. Acute inflammation triggers pain, localized swelling, and mechanical disability, which routinely drives patients toward pharmacological relief. For decades, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, celecoxib, and diclofenac have served as primary clinical interventions. While these synthetic agents effectively extinguish acute pain signals, expanding cellular and clinical research indicates that their biochemical mechanism interrupts the fundamental repair cascades required for long-term connective tissue healing. In contrast, curcumin - a natural polyphenolic compound derived from the rhizomes of Curcuma longa (turmeric) - exhibits a distinct, multi-targeted regulatory profile that calms hyperactive inflammation while protecting the structural components of cartilage and tendon tissue.The functional divergence between these two compounds becomes clear when considering an intuitive mechanical analogy. Tissue trauma resembles damage to a commercial building, where initial inflammation functions as the construction and demolition crew tasked with clearing rubble, stabilizing the foundation, and laying down fresh structural framing. NSAIDs function like abruptly cutting electrical power to the entire work site: the noisy machinery stops instantly and the immediate disturbance ceases, but the construction workers lose the power necessary to clean the debris and erect permanent walls. Conversely, curcumin operates as an experienced site manager: it silences unnecessary chaos and prevents site vandalism while ensuring that the skilled workers - specifically chondrocytes in cartilage and tenocytes in tendons - remain fully active, supplied, and capable of completing the restoration. At the cellular level, NSAIDs exert their effects through the catalytic inhibition of cyclooxygenase enzymes, categorized as constitutive cyclooxygenase-1 (COX-1) and inducible cyclooxygenase-2 (COX-2). Membrane phospholipids damaged during injury release arachidonic acid, which COX enzymes convert into pro-inflammatory lipid mediators known as prostanoids, most notably prostaglandin E2 (PGE2). Nonselective NSAIDs block both isoforms, while selective coxibs specifically target COX-2. By shutting off PGE2 production, NSAIDs rapidly elevate pain thresholds and blunt localized swelling. However, because PGE2 also functions as a vital signaling cue for cellular recruitment, angiogenesis, and cellular proliferation, this total enzymatic shutdown strips local repair cells of the baseline signals required to orchestrate tissue regeneration. Curcumin avoids this indiscriminate pathway paralysis by acting upstream on master transcriptional control switches rather than directly neutralizing isolated enzymes. Its primary therapeutic mechanism centers on the inhibition of Nuclear Factor-kappa B (NF-kB) and Activator Protein-1 (AP-1) signaling networks. Under acute stress or chronic inflammatory loads, the NF-kB protein complex is released from its cytoplasmic inhibitor, IkBa, and translocates directly into the cell nucleus, where it drives the transcription of catabolic cytokines such as interleukin-1 beta (IL-1ß), tumor necrosis factor-alpha (TNF-a), and interleukin-6 (IL-6). Curcumin blocks the phosphorylation and degradation of IkBa, effectively keeping NF-kB trapped in the cytoplasm. By preventing this nuclear entry, curcumin attenuates the expression of pro-inflammatory cytokines and downstream matrix-degrading enzymes while preserving baseline physiological functions. Furthermore, curcumin activates the nuclear factor erythroid 2-related factor 2 (Nrf2) and antioxidant response element (ARE) pathways, which upregulate endogenous cellular antioxidants to neutralize destructive reactive oxygen species (ROS) that induce cell death in injured joints.
The Mechanisms of NSAID-Induced Inhibition in Cartilage and Tendon RepairArticular cartilage and tendons are specialized, bradytrophic connective tissues characterized by relatively low basal metabolic rates and limited endogenous vascular supplies. These physical constraints make their cellular maintenance highly vulnerable to pharmaceutical disruptions. When synthetic compounds impair cell migration, survival, or extracellular matrix secretion, the intrinsic repair capacity of these structures is substantially degraded.Cartilage maintenance depends on chondrocytes, the sole cell type residing within articular joints, which are responsible for generating and maintaining the extracellular matrix of Type II collagen and water-binding proteoglycans such as aggrecan. Because adult articular cartilage lacks a direct vascular network, major defect repair relies heavily on the recruitment and chondrogenic differentiation of subchondral mesenchymal stem cells (MSCs) through endochondral ossification. Experimental evaluations demonstrate that systemic or intra-articular NSAID exposure halts this regenerative differentiation. Both nonselective NSAIDs and selective COX-2 inhibitors interfere with chondrocyte maturation and prevent successful tissue integration following cartilage transplantation or microfracture procedures. At the cellular level, common NSAIDs - including indomethacin, ketorolac, and diclofenac - induce cell cycle arrest in chondrocytes by blocking transition from the resting G0 phase to the proliferative G1. phase, substantially reducing viable cell numbers. Concurrently, NSAIDs downregulate Bone Morphogenetic Protein-2 (BMP-2), an essential anabolic signaling molecule that orchestrates matrix synthesis. Histological analyses in animal models reveal that NSAID administration causes a marked loss of extracellular proteoglycan content and widespread chondrocyte depletion, yielding elevated modified Mankin scores that signify advanced structural degeneration. In layman's terms, proteoglycans serve as water-absorbing structural sponges that grant cartilage its elastic shock absorption. When NSAIDs deplete these molecules, the joint surface dries out, becomes brittle, and rapidly wears down under routine mechanical friction. Tendon healing is similarly susceptible to disruption by NSAIDs. Tendons operate as high-tensile structural cables composed of longitudinally arranged Type I collagen fibers, maintained by specialized fibroblasts termed tenocytes and tenoblasts. Healing after acute rupture or chronic tear progresses through an initial inflammatory phase, followed by a proliferative phase of cell migration, and culminates in a lengthy remodeling phase of collagen alignment. In vitro and in vivo studies establish that NSAIDs directly suppress the migration and proliferative capacity of tenocytes during the critical early healing window. Without an adequate cellular workforce migrating into the wound bed, provisional collagen scaffolding cannot be synthesized effectively. The disruption is particularly pronounced at the enthesis, the specialized fibrocartilaginous junction where soft tendon inserts into rigid bone. Re-establishing this transition zone requires coordinated bone remodeling and chondrogenic differentiation, both of which are hindered by COX inhibition. In animal rotator cuff repair models, early administration of NSAIDs significantly delays collagen fiber organization and impairs mechanical integration at the insertion site, resulting in a measurable decline in load-to-failure strength and overall tendon toughness. Furthermore, while prolonged inflammation contributes to pathological degeneration, the transient synthesis of PGE2 during the initial hours following injury is essential for regulating localized microvascular flow and hyperemic nutrient delivery. By eliminating this early prostanoid pulse, NSAIDs starve the repair zone of oxygen and circulating factors precisely when the cellular metabolic demand is highest. Beyond direct biochemical cytotoxicity, systemic NSAIDs introduce a physical hazard known as analgesic arthropathy. In musculoskeletal biomechanics, pain functions as a protective feedback mechanism, forcing the patient to unload an injured joint or limb to prevent structural overload. By effectively blunting the pain reflex while simultaneously undermining the cellular synthesis of proteoglycans and collagen, NSAIDs create a deceptive state of perceived recovery. Patients prematurely resume unrestricted weight-bearing and strenuous activity, placing substantial, uncompensated mechanical forces onto compromised cartilage surfaces and unhealed tendon fibers. Over time, this recurring mechanical trauma accelerates joint space narrowing, promotes microfractures in the subchondral plate, and hastens functional joint breakdown. Chondroprotective and Tenogenic Mechanisms of CurcuminIn sharp contrast to the suppressive actions of synthetic COX inhibitors, curcumin exhibits a tissue-sparing, pro-regenerative biological profile. Rather than paralyzing cellular metabolism, curcumin modulates the microenvironment by suppressing destructive catabolic enzymes while supporting the baseline anabolic signals required for cartilage and tendon reconstruction.In articular cartilage, curcumin acts as a direct chondroprotective agent by dismantling the catabolic cascade induced by pro-inflammatory cytokines. When joint tissues are exposed to elevated IL-1ß and TNF-a, chondrocytes are provoked to synthesize matrix metalloproteinases - specifically collagenases such as MMP-1, MMP-3, and MMP-13 - along with aggrecanases like ADAMTS5. These enzymes function like enzymatic shears, systematically slicing through structural Type II collagen strands and degrading aggrecan cores. Curcumin suppresses the transcription and secretion of MMP-1, MMP-3, MMP-13, and ADAMTS5 by neutralizing NF-kB and AP-1 activation. Concurrently, it upregulates Cbp/p300 Interacting Transactivator with ED-rich tail 2 (CITED2), an essential transcriptional regulator that represses matrix metalloproteinases at the genomic level. In addition to halting extracellular degradation, curcumin protects chondrocytes from inflammatory apoptosis. Exposure to oxidative stress and inflammatory cytokines typically triggers programmed cell death by activating the intrinsic caspase cascade. Curcumin suppresses this apoptotic pathway by reducing the cleavage of executioner caspase-3, downregulating the pro-apoptotic factor Bax, and elevating anti-apoptotic Bcl-2 expression. Microscopic and histological analyses of osteoarthritic cartilage treated with curcumin consistently show robust Safranin O staining, intact surface regularity, preserved chondrocyte density, and significantly reduced Osteoarthritis Research Society International (OARSI) degradation scores. Within tendon biology, curcumin promotes active tissue regeneration (tenogenesis) rather than inert scar formation. In animal models of tendon rupture and surgical repair, curcumin guides tendon-derived stem and progenitor cells (TSPCs) toward mature tenocyte differentiation. This lineage-specific differentiation is orchestrated primarily through activation of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) and Wnt/ß-catenin signaling cascades. As stem cells commit to the tenogenic pathway, they significantly upregulate crucial structural and phenotypic markers, including epithelial cell adhesion molecule (EpCAM), tenomodulin, and the master tendon transcription factor Scleraxis. Through this guided differentiation, curcumin supports the preferential synthesis and organized deposition of high-tensile Type I collagen fibers, the primary architectural building blocks of healthy tendons. Injured tendons typically fill with disorganized, loose Type III collagen, which forms a structurally inferior, compliant scar. Curcumin supplementation promotes the progressive maturation from primitive Type III collagen to densely packed, parallel Type I collagen fibrils, restoring native tensile strength and mechanical breaking force. A major clinical challenge following tendon surgery is the development of peritendinous adhesions, in which excessive fibrotic scar tissue binds the healing tendon to its synovial sheath, restricting range of motion and joint gliding. Postoperative tendon repair involves a balance between extrinsic healing (in which exterior fibroblasts infiltrate the defect and deposit messy scar tissue) and intrinsic healing (in which tenocytes within the tendon substance reconstruct the matrix). Curcumin suppresses excessive peritendinous inflammation and extrinsic fibrosis while accelerating intrinsic tenocyte repair. Biomechanical testing confirms that local or systemic curcumin administration yields lower adhesion scores, increased gliding distances, and superior functional mobility without sacrificing structural load-bearing capacity. Comparative Clinical Efficacy and Systemic Safety ProfilesTranslating cellular findings into clinical practice requires weighing therapeutic outcomes against systemic safety profiles. While synthetic NSAIDs deliver potent, rapid analgesia during acute musculoskeletal pain events, their chronic administration is constrained by systemic toxicities across multiple organ systems.In randomized, active-controlled clinical trials of knee osteoarthritis, optimized curcumin preparations have demonstrated clinical pain reduction and functional recovery comparable to standard therapeutic doses of NSAIDs. In a randomized, open-label parallel-arm study evaluating 139 patients with symptomatic knee osteoarthritis, subjects received either 500 mg of a bio-enhanced curcumin extract three times daily or 50 mg of diclofenac sodium twice daily for 28 consecutive days. Patients treated with curcumin demonstrated comparable improvements in pain intensity on the Visual Analogue Scale (VAS) and functional scores on the Knee Injury and Osteoarthritis Outcome Score (KOOS) at days 14 and 28, showing no statistically significant difference in therapeutic efficacy compared to diclofenac. However, the systemic tolerability profiles between the treatments diverged markedly. Overall adverse events occurred in only 13% of the curcumin group compared to 38% of the diclofenac cohort. In the diclofenac arm, 28% of patients developed dyspeptic symptoms severe enough to require concurrent treatment with H2-receptor antagonists or proton pump inhibitors to prevent mucosal ulceration, whereas no patients in the curcumin cohort required gastroprotective intervention. Furthermore, the curcumin cohort experienced a significant reduction in flatulence and digestive discomfort, demonstrating beneficial gastric and intestinal cytoprotective effects. These safety observations are consistent across broader systematic reviews and meta-analyses. Nonsteroidal anti-inflammatory agents inherently compromise gastrointestinal integrity by systematically depleting cytoprotective prostaglandins, leaving the gastric epithelium vulnerable to acid erosion and hemorrhage. In addition, systemic inhibition of renal and vascular COX enzymes by NSAIDs reduces renal perfusion and disrupts the balance between prostacyclin and thromboxane, elevating the risk of fluid retention, hypertension, and adverse cardiovascular thrombotic events. Curcumin does not suppress these physiological prostanoid pathways, making it free from ulcerogenic, nephrotoxic, and cardiotoxic properties at therapeutic dosages.
A longstanding limitation of standard curcumin supplementation in clinical settings has been its low oral bioavailability. Native curcuminoids are highly lipophilic, poorly soluble in aqueous gastric fluids, and subject to rapid hepatic and intestinal phase II metabolism into inactive glucuronides and sulfates, leading to swift biliary and fecal excretion. Consequently, raw culinary turmeric powders struggle to achieve the therapeutic systemic circulating concentrations required to reach poorly vascularized joint and tendon compartments. Modern pharmacognosy has addressed this pharmacodynamic hurdle through advanced delivery formulations. Modern strategies - such as co-administration with the natural alkaloid piperine (which inhibits hepatic glucuronidation), micellar dispersions, phytosomal phospholipid complexes, and bio-enhanced submicron dispersions - elevate systemic blood bioavailability by ten- to thirty-fold compared to unformulated extracts. These modern delivery platforms ensure that therapeutic concentrations reach synovial fluid, subchondral bone, and fibrous tendon sheaths without requiring excessive oral dosing. Conclusions and Translational Clinical ImplicationsThe biological and clinical evidence reveals distinct physiological paths for NSAIDs and curcumin in orthopedic recovery. While NSAIDs remain powerful tools for the brief alleviation of acute, unmanageable pain, their ongoing administration during active tissue healing presents substantial biological compromises. Tendons and cartilage require a controlled, transient inflammatory cascade to signal cell recruitment, stimulate stem cell differentiation, and direct extracellular matrix synthesis. By completely shutting down cyclooxygenase enzymes and depleting local prostaglandins, NSAIDs disrupt this regenerative cascade. The resulting cellular consequences - including chondrocyte cell cycle arrest, proteoglycan loss, suppression of tenocyte migration, and weakened collagen tensile strength at the tendon-to-bone interface - demonstrate that pain relief from NSAIDs frequently comes at the cost of the structural integrity of healing connective tissues.In contrast, curcumin provides a tissue-preserving alternative that decouples pain and inflammation control from cellular suppression. Operating upstream at the level of NF-kB and AP-1 transcriptional activation, curcumin attenuates the expression of pro-inflammatory cytokines while leaving the physiological baseline of cellular metabolism intact. In cartilage, it actively represses the matrix-degrading enzymes MMP-1, MMP-3, MMP-13, and ADAMTS5, maintains water-binding proteoglycan content, and protects chondrocytes from inflammatory apoptosis. In damaged tendons, curcumin stimulates tenogenic differentiation of local stem cells via PI3K/Akt signaling, supports the proper maturation of dense Type I collagen fibers, and prevents restrictive peritendinous scar adhesions, preserving both joint mobility and mechanical breaking strength. From a translational perspective, these findings indicate that clinical protocols should reconsider relying on continuous NSAIDs as the default intervention for connective tissue injuries, post-surgical recovery, and chronic degenerative conditions. Where synthetic NSAIDs are deemed necessary, their use should be confined to short-term acute flare-ups to avoid interrupting early tissue remodeling. For long-term joint preservation, ongoing tendinopathy rehabilitation, and chronic osteoarthritis management, optimized bio-enhanced curcumin formulations deliver pain relief and functional restoration comparable to conventional pharmaceuticals, all while preserving the biological processes required for lasting musculoskeletal repair. References: NSAID therapy effects on healing of bone, tendon, and the enthesis The Detrimental Effects of Systemic Ibuprofen Delivery on Tendon Conservative management of symptomatic knee osteoarthritis - PMC Positives and negatives of nonsteroidal anti-inflammatory drugs in (PDF) Conservative management of symptomatic knee osteoarthritis Non-steroidal anti-inflammatory drugs influence cartilage healing Is Curcumine Useful in the Treatment and Prevention of ... - PMC - NIH Efficacy and mechanisms of curcumin in the treatment of osteoarthritis Biological actions of curcumin on articular chondrocytes - PubMed Curcumin slows osteoarthritis progression and relieves ... - PMC - NIH Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Anti-inflammatory management for tendon injuries - friends or foes? The mechanistic role of curcumin on matrix metalloproteinases in Therapeutic effects of turmeric or curcumin extract on pain and Curcumin inhibits chondrocyte apoptosis and inflammation in ... - PMC Analysis of the mechanism of curcumin against osteoarthritis using Synergistic enhancement of tendon-to-bone healing via anti ... - PMC A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis A randomized, pilot study to assess the efficacy and safety ... - PubMed Effectiveness of curcuminoids in the treatment of knee osteoarthritis THE EFFECTS OF TRADITIONAL STRENGTHENING EXERCISES Putting Some Muscle into Osteoarthritis | Annals of Internal Medicine Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Calebin A, a Compound of Turmeric, Down-Regulates Inflammation The Effect of Non-Steroidal Anti-Inflammatory Drugs on Tendon-to Chiropractor in Toronto, ON, Canada :: Head and Neck Pain Investigation of the association of long-term NSAID use with ... - PMC Curcumin Improves Functional Recovery of Ruptured Tendon by Chemically modified curcumin (CMC2.24) alleviates osteoarthritis Curcumin improves age-related and surgically induced osteoarthritis (PDF) Curcumin Improves Functional Recovery of Ruptured Tendon Investigation of the effects of umbilical cord-derived mesenchymal Effect of curcumin-loaded polycaprolactone scaffold on Achilles Controlled release of curcumin from curcumin-loaded nanomicelles Efficacy and safety of combination of curcuminoid complex ... - PMC The efficacy of Curcuma Longa L. extract as an adjuvant therapy in
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6653) Pine Bark vs. Grape Seed: Comparing Antioxidant Absorption 
Date:
September 11, 2026 10:33 AM
The Ultimate Guide to Plant-Based Antioxidants: Pine Bark Extract vs. Grape Seed ExtractIf you have ever left a sliced apple on the counter and watched it turn brown, you have witnessed oxidative stress. The same "rusting" process happens inside our bodies every day due to pollution, stress, poor diet, and natural aging. To fight this, our bodies rely on antioxidants—microscopic defenders that neutralize the damage.While vitamins C and E are famous antioxidants, the plant kingdom offers something much stronger. Two of the most powerful natural antioxidants on the planet are extracted from parts of plants we usually throw away: the bark of pine trees and the seeds of grapes. If you're looking to boost your health, you might find yourself stuck trying to figure out pine bark extract vs grape seed extract. And more specifically, you might be wondering about Pycnogenol vs grape seed extract. Let's break down the science of these plant-based powerhouses, explain what makes them tick, and look at how well your body actually absorbs them—all without needing a degree in chemistry. The Secret Ingredient: What are OPCs?To understand why these two extracts are so powerful, you need to know a very long word: Oligomeric Proanthocyanidins, or OPCs for short.Think of OPCs as the elite special forces of the antioxidant world. They are natural compounds found in the woody, outer parts of plants (like bark, stems, and seed shells). In nature, OPCs protect the plant from harsh weather, bugs, and UV rays. When we consume them, they offer us incredible protection. In fact, OPCs have been shown to be dramatically more powerful at fighting off cellular damage than standard Vitamin C or Vitamin E. Both pine bark and grape seeds are absolutely packed with OPCs, which is why they are so famous in the wellness world. Grape Seed Extract (GSE): The Circulation ChampionJust as the name suggests, Grape Seed Extract is pulled from the seeds of grapes (usually red wine grapes). For decades, scientists wondered why certain European cultures could eat diets high in rich foods and fats but still maintain incredible heart health. Part of the answer was found in the grapes they used to make wine.What it does: Grape Seed Extract is famous for supporting blood vessels. It helps keep your arteries flexible and strong, which promotes healthy blood pressure and reduces swelling (edema) in the legs. The makeup: GSE is highly concentrated with OPCs. It also contains a unique compound called gallic acid, which is excellent for fighting inflammation. Pine Bark Extract and Pycnogenol: The Premium DefenderPine bark extract comes from the inner bark of pine trees. While there are many generic pine bark supplements, you will almost always see the name Pycnogenol.What is Pycnogenol? Pycnogenol is a patented, highly standardized form of pine bark extract sourced exclusively from the French maritime pine tree. Because it is trademarked, every batch is guaranteed to have the exact same ratio of active ingredients. When scientists study pine bark, they are almost always studying Pycnogenol. What it does: Like grape seed extract, Pycnogenol is fantastic for blood flow. However, it is also famous for its effects on the skin and joints. It actually binds to collagen and elastin - the proteins that keep your skin looking plump and youthful—and protects them from breaking down. The Main Event: Pycnogenol vs Grape Seed ExtractSo, if both of these supplements are packed with OPCs, what is the difference? The real battle comes down to bioavailability (absorption rates).What is Bioavailability?"Bioavailability" is just a fancy way of asking: How much of this actually makes it into my bloodstream?You can swallow 1,000 milligrams of a supplement, but if your body can't absorb it, it just passes through your digestive tract and ends up in the toilet. To get into your bloodstream, antioxidant molecules have to be small enough to pass through the lining of your gut. The Size of the Molecules (Oligomers vs. Polymers)Here is where the comparison between pine bark extract vs grape seed extract gets interesting.OPCs come in different sizes.
The Grape Seed Absorption ProfileGrape seeds naturally contain a very wide mix of both small oligomers and large polymers. If you buy a cheap, low-quality grape seed extract, you might be getting a lot of large polymers that your body cannot absorb. However, high-quality, standardized Grape Seed Extracts are specially filtered to ensure they contain mostly small, easily absorbed OPCs. Once absorbed, the gallic acid in grape seed extract stays in the blood for a long time, providing excellent, long-lasting antioxidant protection.The Pine Bark (Pycnogenol) Absorption ProfilePycnogenol is famous precisely because of its absorption. The natural composition of the French maritime pine tree bark is already heavily skewed toward the smaller, highly absorbable oligomers. Furthermore, because Pycnogenol is a strictly controlled, patented extract, the molecule size is guaranteed. When you take it, you know with absolute certainty that a massive percentage of those OPCs are crossing the gut barrier and entering your system rapidly.Which One Should You Choose?Both extracts are spectacular choices for fighting oxidative stress, but your choice depends on your specific health goals and your budget.Choose Grape Seed Extract if:
The Bottom LineWhen comparing Pycnogenol vs grape seed extract, there is no "loser." Both are incredibly potent sources of plant-based antioxidants that protect your body from cellular rust.If you are looking for an affordable, heart-healthy daily shield, high-quality Grape Seed Extract is a phenomenal choice. If you are willing to spend a little more for a premium, heavily researched extract that targets skin, joints, and guaranteed absorption, Pycnogenol is the gold standard.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6651) The Ultimate Guide to Cellular Longevity: NAD+, Methylation, and Senolytics
Date:
September 10, 2026 10:57 AM
Introduction: Understanding Cellular Aging and Energy DeclineBiological aging represents a progressive decline in cellular maintenance, structural repair, and energy generation. Over decades, tissues experience an attrition of functional reserves, compromised stress resilience, and persistent low-grade systemic inflammation. At the cellular scale, biological degeneration is driven by a failure to generate bioenergetic fuel, repair genetic code, and clear metabolic waste.Cellular aging is characterized by interconnected biological disruptions known as the hallmarks of aging. These encompass genomic instability, epigenetic alterations, mitochondrial decay, loss of proteostasis, and cellular senescence. Rather than operating as isolated occurrences, these phenomena establish a self-reinforcing degenerative cycle: declining cellular power generation impairs enzymatic genetic repair, promoting the accumulation of damaged cells that enter irreversible growth arrest and poison surrounding healthy tissues. Mitigating cellular aging requires examining how microscopic bioenergetic pathways deteriorate and evaluating how targeted nutritional and biochemical interventions can restore cellular homeostasis. The Role of Mitochondria and ATP ProductionEvery biological function - from muscular contraction to continuous DNA replication - depends on adenosine triphosphate (ATP), the primary biochemical energy currency of living systems. Cells produce the vast majority of this energy within mitochondria through oxidative phosphorylation. Within these specialized organelles, metabolic intermediates derived from dietary carbohydrates and lipids donate high-energy electrons to the electron transport chain. The flow of these electrons across protein complexes establishes an electrochemical proton gradient across the inner mitochondrial membrane, driving ATP synthase to manufacture ATP.A youthful cell functions like an efficient municipal power grid, dynamically matching energetic demands with immediate ATP output. However, as biological aging progresses, mitochondrial efficiency declines. The electron transport chain becomes structurally leaky, inadvertently shedding electrons that react with ambient molecular oxygen to produce reactive oxygen species (ROS). While regulated levels of ROS participate in vital intracellular signaling, chronic excess induces widespread oxidative stress. Mitochondria are exceptionally vulnerable to this oxidative burden because they carry their own circular genetic material, known as mitochondrial DNA (mtDNA). Unlike nuclear DNA, mtDNA lacks the protective shielding of histone proteins and possesses rudimentary repair systems. As a result, mtDNA sustains cumulative oxidative damage, encoding increasingly defective electron transport chain proteins. This dynamic generates a bioenergetic deficit: degraded mitochondria synthesize progressively less ATP while emitting greater volumes of damaging free radicals. Deprived of optimal ATP reserves, cells lack the energy necessary to drive vital enzymatic repair cascades, accelerating structural degeneration and functional exhaustion. How Cellular Senescence Accelerates the Aging ProcessWhen healthy cells confront critical physiological damage - such as severe telomere attrition, persistent DNA double-strand breaks, or oxidative stress - they activate protective cell cycle arrest pathways governed primarily by the p53/p21^CIP1 and p16^INK4a/Rb molecular checkpoints. This defensive shutdown, termed cellular senescence, permanently prevents the replication of potentially premalignant or mutated cells.Senescent cells, colloquially known as "zombie cells," enter a state of permanent growth arrest while actively resisting programmed cell death (apoptosis). Over time, these cells accumulate within adipose depots, skeletal muscle, the vascular endothelium, and major organs, largely because immune surveillance and clearance pathways simultaneously lose functional efficiency. The systemic danger of senescent cells stems from their secretome. Rather than remaining biologically inert, senescent cells develop a hyperactive secretory state termed the Senescence-Associated Secretory Phenotype (SASP). The SASP is a destructive mixture of pro-inflammatory cytokines, chemokines, extracellular matrix-degrading matrix metalloproteinases (MMPs), and reactive oxygen species. Through this toxic secretome, even a small burden of senescent cells can impair whole-tissue architecture. SASP factors degrade surrounding structural proteins, induce insulin resistance in neighboring metabolic cells, and biochemically force adjacent healthy cells into secondary senescence. This persistent paracrine signaling fuels chronic, sterile, low-grade systemic inflammation, termed "inflammaging," which accelerates systemic tissue degeneration and elevates susceptibility to degenerative age-related pathologies. Nicotinamide Riboside (NR) and the NAD+ Salvage PathwayThe Biochemistry of NAD+ Depletion Over TimeNicotinamide adenine dinucleotide (NAD+) is an indispensable coenzyme present in every living cell. NAD+ fulfills a dual biological mandate: it serves as a central redox cofactor that shuttles electrons between cellular metabolic reactions, and it functions as an obligatory consumable substrate for regulatory enzymes that preserve cellular viability. In its redox capacity, NAD+ accepts electrons to form NADH during glycolysis, the tricarboxylic acid (TCA) cycle, and fatty acid beta-oxidation, subsequently donating those electrons to Complex I of the respiratory chain to power ATP synthesis.
The primary enzymatic driver of age-related NAD+ destruction is CD38, a membrane-bound glycohydrolase expressed on immune cells that is upregulated in response to chronic SASP exposure. Concurrently, lifelong genotoxic damage causes persistent activation of Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that cleaves the glycosidic bonds of NAD+ to assemble branched poly(ADP-ribose) chains at DNA lesion sites. Because PARP-1 consumes NAD+ without directly recycling the molecule, chronic DNA damage depletes intracellular NAD+ pools, impairing bioenergetics and limiting sirtuin activity. How NR Efficiently Boosts Cellular NAD+ LevelsThe mammalian body maintains its NAD+ supply through three distinct biosynthetic routes: the de novo pathway from dietary L-tryptophan, the Preiss-Handler pathway from nicotinic acid (niacin), and the NAD+ Salvage Pathway. The de novo pathway requires substantial energy expenditure, consuming roughly sixty milligrams of dietary tryptophan to yield a single milligram of NAD+. The Preiss-Handler pathway, while effective, can induce cutaneous prostaglandin-mediated flushing at therapeutic intakes. Consequently, the salvage pathway serves as the primary mechanism for maintaining intracellular NAD+ pools.The salvage pathway recycles the breakdown product nicotinamide (NAM), which is released whenever NAD+-consuming enzymes execute their functions. Under normal conditions, cells convert free nicotinamide into nicotinamide mononucleotide (NMN) via the rate-limiting enzyme nicotinamide phosphoribosyltransferase (NAMPT), after which NMN adenylyltransferases (NMNAT1–3) complete the conversion into NAD+. However, NAMPT expression declines with advancing age, chronic inflammation, and metabolic stress, limiting the recycling capacity of the cell. Nicotinamide Riboside (NR) is a naturally occurring pyridine nucleoside that bypasses this enzymatic bottleneck. Upon cellular entry via equilibrative nucleoside transporters, NR is directly phosphorylated into NMN by nicotinamide riboside kinases (NRK1 and NRK2) using a single molecule of ATP. Because the NRK pathway remains intact and robust across the lifespan, NR provides an efficient alternative entry point into the NAD+ salvage cascade. Clinical evaluations in humans confirm the safety, bioavailability, and pharmacokinetics of oral NR supplementation. Randomized, double-blind, placebo-controlled trials reveal that oral NR chloride produces dose-dependent increases in steady-state whole blood NAD+ concentrations. Dosing regimens of 100 mg, 300 mg, and 1,000 mg daily elevate blood NAD+ levels by approximately 22%, 51%, and up to 142%, respectively, within two weeks of administration, maintaining these elevations throughout continuous use. High-resolution metabolomic analyses also demonstrate parallel elevations in nicotinic acid adenine dinucleotide (NAAD), establishing it as a reliable biomarker of active intracellular NAD+ synthesis without hepatic or systemic toxicity. Sirtuin Activation and DNA Repair MechanismsReplenishing intracellular NAD+ supports functions beyond mitochondrial ATP generation. NAD+ functions as an obligatory cofactor for sirtuins (SIRT1 through SIRT7), a family of class III histone and non-histone protein deacetylases that regulate stress resilience, metabolic homeostasis, and cell survival. Sirtuins couple the removal of acetyl groups from target lysine residues to the stoichiometric cleavage of NAD+, producing nicotinamide and O-acetyl-ADP-ribose. In states of NAD+ deficiency, sirtuin enzymes remain inactive regardless of cellular demand.In the nucleus, SIRT1 coordinates defense against cellular decline. When activated by restored NAD+ levels, SIRT1 deacetylates peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1a), the master transcriptional coactivator of mitochondrial biogenesis. This deacetylation stimulates mitochondrial replication and assembly, expanding functional respiratory capacity. Concurrently, SIRT1 deacetylates the p65 subunit of nuclear factor-kappa B (NF-kB), suppressing the transcription of pro-inflammatory cytokines. In the mitochondria, SIRT3 utilizes NAD+ to deacetylate metabolic enzymes and superoxide dismutase 2 (SOD2), enhancing the organelle's capacity to neutralize reactive oxygen species. At the same time, cellular NAD+ levels directly regulate genomic integrity through PARP-1. When genotoxic stress or oxidative damage induces single- or double-strand DNA breaks, PARP-1 binds to the damaged termini using its zinc-finger domains. Bound PARP-1 hydrolyzes NAD+ to synthesize extensive, negatively charged poly(ADP-ribose) polymers on itself and adjacent histones. This modification relaxes chromatin architecture and establishes an electrostatic scaffold that recruits base excision repair and homologous recombination complexes. Recent discoveries demonstrate close crosstalk between sirtuins and PARP-1 during DNA repair. PARP-1 recruits SIRT1 to double-strand breaks, where SIRT1 deacetylates the chromatin-remodeling ATPase BRG1 to displace nucleosomes and facilitate homologous recombination. However, because PARP-1 and SIRT1 draw from the same intracellular NAD+ pool, severe NAD+ depletion forces a biological compromise: PARP-1 consumes the scarce remaining cofactor to address DNA damage, leaving sirtuins deactivated. Restoring NAD+ via NR prevents this deficit, enabling concurrent genomic repair and sirtuin-mediated metabolic defense. Quercetin: A Powerful Senolytic and mTOR RegulatorClearing Senescent "Zombie" Cells from TissuesThe accumulation of senescent cells has driven interest in senolytics: molecules that selectively eliminate senescent cells while sparing healthy, non-senescent populations. Senolytic agents exploit a specific vulnerability in senescent cells. Because senescent cells produce cytotoxic, pro-inflammatory SASP factors that would normally induce their own death, they become dependent on upregulated Senescent Cell Anti-Apoptotic Pathways (SCAPs) to survive. The SCAP network involves anti-apoptotic proteins (such as BCL-2 and BCL-xL), the PI3K/Akt kinase cascade, and cyclin-dependent kinase inhibitors.Quercetin is a polyphenolic flavonoid found in capers, red onions, apples, and the flower buds of Sophora japonica. Beyond its classical antioxidant properties, quercetin functions as a senolytic compound that exerts multi-target inhibitory effects across the SCAP network. By inhibiting the upstream PI3K/Akt survival axis and downregulating anti-apoptotic defenses, quercetin disrupts the signaling that protects senescent cells from intrinsic apoptosis. Deprived of these survival signals, senescent cells undergo programmed cell death. Preclinical studies demonstrate that senolytic protocols utilizing quercetin - often combined with the tyrosine kinase inhibitor dasatinib - reduce senescent cell burden across multiple tissues. This targeted clearance lowers circulating SASP factors, attenuates tissue fibrosis, restores endothelial reactivity, and improves functional health span. By removing senescent cells, quercetin mitigates the primary driver of chronic, low-grade inflammaging. Modulating the mTOR Pathway for Optimal AutophagyThe mechanistic Target of Rapamycin (mTOR) is an evolutionarily conserved serine/threonine protein kinase that coordinates cellular metabolism by balancing anabolic growth with catabolic recycling. Operating within two multiprotein complexes - mTORC1 and mTORC2 - the mTOR pathway integrates signals from amino acids, growth factors, and intracellular energy levels. In nutrient-rich environments, mTORC1 promotes protein synthesis, lipogenesis, and cellular growth, while suppressing catabolic breakdown. Conversely, nutrient scarcity downregulates mTORC1, activating autophagy.Autophagy is an intracellular degradation system that packages damaged organelles, misfolded protein aggregates, and biological debris into double-membraned autophagosomes for lysosomal degradation and recycling. A specialized branch of this pathway, mitophagy, selectively targets and clears damaged mitochondria. In modern metabolic conditions characterized by continuous caloric intake, mTORC1 can remain persistently active. This persistent signaling suppresses autophagy, causing damaged organelles and toxic aggregates to accumulate within tissues. Quercetin functions as a natural modulator of mTOR signaling. By inhibiting upstream PI3K/Akt signaling and activating intracellular energy sensors, quercetin attenuates overactive mTORC1, mimicking the metabolic effects of caloric restriction. This down-regulation relieves inhibition on the ULK1 autophagy initiation complex, stimulating both general autophagy and mitophagy. As autophagy proceeds, cells clear protein aggregates and eliminate damaged mitochondria, supporting cellular longevity and proteostasis. Enhancing Absorption: Phytosomes and Dietary FatsDespite the biological activities of quercetin identified in experimental models, its clinical translation has historically been limited by poor oral bioavailability. Raw quercetin aglycone is a crystalline, hydrophobic polyphenol with poor solubility in water and gastrointestinal fluids. When ingested in unformulated powder forms, quercetin molecules aggregate in the gut lumen, resisting dissolution and passive absorption. Consequently, the vast majority of an unformulated dose passes into the colon unabsorbed, where it undergoes microbial degradation without reaching meaningful systemic concentrations.To address these pharmacokinetic limitations, advanced delivery systems such as phytosomes were engineered. A phytosome is a 100% food-grade molecular complex where individual polyphenolic molecules are bound to dietary phospholipids, typically sunflower-derived phosphatidylcholine. Unlike a classical liposome - which encapsulates water-soluble compounds inside an aqueous core enclosed by a lipid bilayer - a phytosome forms an amphiphilic complex at the molecular level. The polar head of the phosphatidylcholine molecule forms hydrogen bonds with the hydroxyl groups of the quercetin molecule, while its lipophilic fatty acid tails extend outward. This structural arrangement shields the polar regions of the flavonoid, creating a lipid-compatible complex that integrates smoothly into the intestinal mucosa.
The Importance of Methylation in Healthy AgingVitamin B-Complex and Choline as Essential Methyl DonorsMethylation is an essential biochemical process occurring billions of times each second across all human tissues. It involves the transfer of a single-carbon unit - a methyl group consisting of one carbon atom bound to three hydrogen atoms - (CH3) - from a donor molecule to diverse recipients, including DNA, RNA, structural proteins, neurotransmitters, and membrane phospholipids. This transfer of one-carbon units is coordinated by the methionine-homocysteine cycle, which sustains genetic stability, detoxification pathways, and cellular repair.At the center of this pathway sits S-adenosylmethionine (SAM), the universal methyl donor in human biology. When a methyltransferase enzyme transfers a methyl group from SAM to an acceptor molecule, SAM is converted into S-adenosylhomocysteine (SAH). SAH functions as a potent competitive inhibitor of intracellular methyltransferases. To maintain functional methylation, SAH is rapidly hydrolyzed into homocysteine, a sulfur-containing amino acid that must be remethylated or cleared through transsulfuration. Homocysteine clearance proceeds through two distinct remethylation pathways. The primary route operates across most tissues via the enzyme methionine synthase, which requires vitamin B12 in its active methylcobalamin form. Methionine synthase transfers a methyl group from 5-methyltetrahydrofolate (5-MTHF, the active form of folate) to homocysteine, regenerating methionine. The ongoing production of 5-MTHF depends on the enzyme methylenetetrahydrofolate reductase (MTHFR), which utilizes riboflavin (vitamin B2) as a cofactor. Alternatively, excess homocysteine can be routed into the transsulfuration pathway by vitamin B6 (as pyridoxal-5'-phosphate) to synthesize cystathionine, cysteine, and ultimately the antioxidant glutathione. A secondary remethylation pathway, active predominantly in hepatic and renal tissues, bypasses folate entirely. In this route, dietary choline is oxidized to betaine (trimethylglycine or TMG). The enzyme betaine-homocysteine S-methyltransferase (BHMT) then transfers a methyl group from betaine directly to homocysteine, yielding methionine and dimethylglycine. When dietary intake of active B-vitamins or choline is insufficient, or when genetic variations like MTHFR polymorphisms reduce pathway flux, the methylation cycle slows. Homocysteine accumulates in circulation, promoting vascular and neurological inflammation, while SAM reserves decline, restricting cellular methylation capacity. Understanding DNA Methylation and Epigenetic HealthEvery somatic cell in an organism carries an identical genetic code. Cellular differentiation and tissue-specific functions are governed by the epigenome: a regulatory layer of chemical modifications that dictates gene expression without altering underlying DNA sequences. DNA methylation represents the primary and most stable epigenetic modification. In this process, DNA methyltransferase (DNMT) enzymes utilize methyl groups donated by SAM to add a methyl tag to cytosine bases adjacent to guanine residues, forming 5-methylcytosine within CpG dinucleotide sites.Under physiological conditions, DNA methylation maintains genomic stability and coordinates transcription. Methylation of promoter regions condenses chromatin, repressing transposable elements and silencing genes inappropriate for a given cell type. Conversely, hypomethylated promoters maintain an open chromatin state, allowing transcription factors to bind and initiate gene expression. During biological aging, this epigenetic landscape undergoes progressive dysregulation, a phenomenon termed "epigenetic drift". Aging cells experience global hypomethylation alongside focal hypermethylation of specific gene promoters. Global loss of methyl tags destabilizes the genome, activating retrotransposons and pro-inflammatory pathways. Simultaneously, hypermethylation at targeted promoter sites silences critical tumor suppressor genes and DNA repair complexes. This systematic change in DNA methylation patterns is consistent across populations, allowing researchers to develop molecular "epigenetic clocks". Algorithms such as the Horvath clock, PhenoAge, and GrimAge quantify biological age by profiling the methylation status of specific CpG sites across the genome. These clocks assess whether individuals are aging faster or slower than their chronological years. Ensuring a steady supply of methyl donors and preventing unnecessary SAM depletion supports DNMT activity, maintaining epigenetic patterns and genomic stability. How the Methylation Cycle Impacts Energy and Cognitive FocusBeyond long-term epigenetic regulation, the methylation cycle directly modulates immediate biochemical processes that govern daily energy, neurotransmission, and cognitive focus. Compromised methylation capacity frequently manifests as cognitive slowing, executive fatigue, and reduced physical stamina.A major consumer of methyl reserves is the endogenous synthesis of creatine. Approximately 40% of all SAM-derived methyl groups in the human body are utilized by guanidinoacetate N-methyltransferase (GAMT) in the liver to synthesize creatine. Creatine then translocates to the brain and skeletal muscle, where it is phosphorylated into phosphocreatine. Phosphocreatine functions as a rapid energy buffer, donating a high-energy phosphate group to regenerate ADP into ATP in milliseconds during demanding physical or cognitive tasks. When methyl donor availability falls, endogenous creatine synthesis drops, depleting phosphocreatine reserves and increasing susceptibility to neuromuscular and cognitive fatigue. Methylation is equally central to central nervous system architecture. SAM provides methyl groups to convert phosphatidylethanolamine into phosphatidylcholine, the predominant phospholipid comprising neuronal cell membranes and the myelin sheaths that insulate axons. Intact myelin preserves rapid action potential conduction throughout the nervous system. Furthermore, free choline derived from this pathway is the direct precursor to acetylcholine, the neurotransmitter required for attention, working memory, and learning. The methylation cycle also governs monoamine neurotransmitter metabolism. SAM is required for the synthesis of adrenaline (epinephrine) from noradrenaline, while catechol-O-methyltransferase (COMT) relies on SAM to degrade dopamine and norepinephrine within the prefrontal cortex. Sluggish methylation disrupts this balance, contributing to cognitive fatigue, mood variability, and impaired mental performance. Building a Comprehensive Longevity ProtocolSynergizing NR, Quercetin, and Methylated B-VitaminsLongevity supplementation often falters when single molecules are administered in isolation, ignoring interconnected metabolic pathways. Designing an effective cellular longevity protocol requires combining complementary mechanisms that reinforce one another while preventing secondary metabolic deficits. The combination of Nicotinamide Riboside, Quercetin Phytosome, and Methylated B-Vitamins illustrates this multi-target synergy.This synergy is grounded in the direct biochemical intersection between the NAD+ salvage pathway and the methylation cycle. When high-dose NR is supplemented to boost systemic NAD+, sirtuins and PARP enzymes consume the newly synthesized cofactor, generating substantial quantities of free nicotinamide (NAM). This intracellular nicotinamide faces two primary metabolic fates: it can be recycled back into NAD+ through the NAMPT-dependent salvage loop, or it can be cleared via methylation. When the influx of nicotinamide exceeds salvage recycling capacity, the excess is cleared to avoid feedback inhibition of sirtuin enzymes. To accomplish this, the enzyme nicotinamide N-methyltransferase (NNMT) transfers a methyl group from SAM directly onto nicotinamide, forming 1-methylnicotinamide (1-MNA/MNAM), which is subsequently excreted in urine. Prolonged, high-dose precursor administration without nutritional methyl support can elevate NNMT flux, depleting intracellular SAM reserves. As methyl groups are consumed clearing nicotinamide, the cellular SAM-to-SAH ratio falls, which can elevate circulating homocysteine and reduce methyl availability for DNA methylation and neurotransmitter synthesis. Co-administering a fully methylated B-complex alongside choline or betaine addresses this potential bottleneck. Providing active methyl donors (such as 5-MTHF, methylcobalamin, and betaine) maintains the one-carbon donor pool. Even during increased NNMT activity, SAM pools remain stable, protecting DNA methylation fidelity and maintaining homocysteine within safe parameters. Quercetin reinforces this protocol through complementary mechanisms. By clearing senescent cells and reducing SASP-mediated inflammation, quercetin downregulates CD38, the primary enzyme responsible for age-related NAD+ degradation. Suppressing CD38 prevents unnecessary breakdown of newly synthesized NAD+, enhancing the efficiency of NR supplementation. Furthermore, while NR provides the NAD+ necessary to activate SIRT1-driven mitochondrial biogenesis, quercetin concurrently modulates mTORC1 to stimulate autophagy. This coordinated action ensures that newly generated mitochondria operate in an environment cleared of proteotoxic cellular debris. The Crucial Role of Magnesium Glycinate and Zinc in Cellular FunctionLongevity protocols require essential mineral cofactors to function efficiently. Without adequate divalent minerals acting as enzymatic cofactors and structural stabilizers, metabolic longevity pathways cannot operate at full capacity. Among these, magnesium and zinc are required for cellular repair, genomic stability, and energy production.Magnesium serves as an obligatory cofactor in over 300 enzymatic reactions, primarily through its interaction with ATP. In biological systems, ATP exists predominantly as a chelate with a divalent magnesium ion, forming biologically active Mg2+ -ATP. Every enzymatic reaction that synthesizes, transfers, or consumes cellular energy - including the enzymes of the NAD+ salvage pathway (NRK and NMNAT) and DNA polymerases - strictly requires Mg2+ -ATP as its substrate. Magnesium deficiency impairs these phosphorylation reactions, reducing the cellular utilization of NAD+ precursors. Additionally, magnesium is an essential cofactor for the enzymes that activate dietary B-vitamins into their active forms. Supplying magnesium as magnesium glycinate provides high gastrointestinal bioavailability, minimal laxative effect, and yields glycine to support inhibitory neurotransmission and restful sleep. Zinc serves as a vital structural component for more than 3,000 human transcription factors and enzymatic proteins. Its most prominent structural role in longevity occurs within zinc-finger motifs. These are specialized protein conformations stabilized by a zinc ion coordinated to cysteine and histidine residues. The DNA damage sensor PARP-1 utilizes three zinc-finger domains to identify, track, and physically bind to single- and double-strand DNA breaks. Without adequate intracellular zinc, PARP-1 cannot properly assemble or dock onto damaged chromosomes, impairing DNA repair and increasing genomic instability. Zinc is also an obligatory structural component of copper/zinc superoxide dismutase (Cu/Zn-SOD or SOD1), the primary cytosolic antioxidant enzyme that dismutates superoxide radicals into hydrogen peroxide, protecting mitochondrial membranes and nuclear DNA from premature senescence. Integrating Prebiotics (like Acacia and Inulin) for Gut-Derived Longevity MarkersA comprehensive cellular longevity framework must extend beyond somatic tissues to encompass the gut microbiome. The intestinal microbiome functions as a central regulator of systemic inflammatory tone, immune development, and metabolic signaling. Age-associated dysbiosis - characterized by the loss of beneficial commensals and an overgrowth of pathobionts - frequently leads to breakdown of the intestinal barrier.The gut epithelium consists of a single-cell monolayer sealed by tight junction proteins, including zonula occludens-1 (ZO-1), occludin, and claudins. When this physical barrier is disrupted by poor dietary fiber intake or dysbiosis, gut permeability increases. This allows lipopolysaccharide (LPS), a component of the outer membrane of Gram-negative bacteria, to enter the portal and systemic circulation. The resulting "metabolic endotoxemia" activates Toll-like receptor 4 (TLR4) on immune cells, inducing NF-kB and systemic pro-inflammatory cytokine production. This persistent gut-derived inflammation exacerbates the SASP, accelerates tissue senescence, upregulates CD38, and drains systemic NAD+ reserves.
These short-chain fatty acids, particularly butyrate, exert direct protective effects on systemic longevity. Butyrate provides the primary metabolic fuel for colonic epithelial cells, supplying more than 70% of their baseline energy needs and supporting mitochondrial function within colonocytes. Furthermore, SCFAs upregulate the expression of epithelial tight junction proteins (ZO-1, occludin, and claudin-1), restoring intestinal barrier integrity and preventing the translocation of inflammatory LPS into systemic circulation. Systemically absorbed butyrate also functions as an endogenous histone deacetylase (HDAC) inhibitor, suppressing pro-inflammatory gene expression and supporting regulatory T cell (T_reg) development. Reducing metabolic endotoxemia dampens systemic inflammation, protecting vascular function and preventing premature NAD+ depletion. Conclusion: The Integrated Cellular Longevity MatrixCellular longevity is achieved not by addressing isolated biomarkers in isolation, but by systematically supporting interconnected biological pathways. As bioenergetic capacity declines, cellular senescence accelerates, epigenetic patterns degrade, and gut barrier integrity weakens. A comprehensive approach addresses these biological vulnerabilities simultaneously.
Quercetin Phytosome clears senescent cells and modulates mTORC1, stimulating autophagy while dampening the inflammatory SASP cascade that accelerates CD38-mediated NAD+ destruction. Methylated B-vitamins, active folate, and choline replenish SAM reserves, balancing the methyl requirements of NNMT-mediated nicotinamide clearance, preserving epigenetic DNA methylation, and maintaining neurotransmitter production. Magnesium glycinate and zinc provide the structural and catalytic foundation required for ATP utilization, B-vitamin activation, and PARP-1 zinc-finger DNA repair docking. Finally, prebiotic fibers generate short-chain fatty acids like butyrate, reinforcing the intestinal barrier and preventing metabolic endotoxemia from fueling systemic inflammation. By coordinating energy replenishment, cellular waste clearance, epigenetic maintenance, and the suppression of systemic inflammation, this unified approach directly addresses the underlying drivers of cellular aging to support long-term physiological vitality.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6650) Stevia: A Zero-Calorie Sweetener
Date:
June 03, 2024 04:15 PM
Stevia: A Zero-Calorie SweetenerIn a world where health consciousness is increasingly important, finding the right sweetener can be a game changer. One such alternative that has gained significant attention is Stevia. Known for its zero-calorie content, Stevia offers a natural sweetness without the drawbacks associated with sugar. This article examines the properties of Stevia, how it’s harvested, its sweetness compared to sugar, and its benefits for those managing diabetes.
What is Stevia?Stevia is a natural sweetener derived from the leaves of the Stevia rebaudiana plant, native to South America. Unlike artificial sweeteners, Stevia is completely natural and has been used for centuries by indigenous people in countries like Brazil and Paraguay. The leaves of the plant contain sweet-tasting compounds known as steviol glycosides, which are the primary components used in Stevia sweeteners found on shelves today.
How Stevia is HarvestedTraditionally, Stevia leaves are harvested by hand. Farmers usually pluck the mature leaves, which are then dried to maintain their sweetness. Once dried, these leaves can be used in their whole form, or they can be processed to extract the steviol glycosides. Modern extraction methods involve soaking the leaves in water and then processing the extract to remove impurities. This results in a highly concentrated sweetener that is hundreds of times sweeter than sugar.
Sweetness Compared to SugarWhen it comes to sweetness, Stevia stands out. Stevia is approximately 200 to 300 times sweeter than sucrose (table sugar). This means a very small amount of Stevia is needed to achieve the desired level of sweetness, which also makes it an efficient option for those looking to cut down on sugar intake. However, it’s important to note that Stevia doesn’t have the exact same taste profile as sugar. Some people describe its sweetness as having a slight, licorice-like aftertaste, which not everyone finds appealing.
Benefits for Those Managing DiabetesFor individuals managing diabetes, Stevia can be an invaluable part of their diet. One of the primary concerns for people with diabetes is managing their blood sugar levels. Traditional sugar can cause spikes in blood glucose, making it difficult to control diabetes symptoms. Stevia, on the other hand, does not contain carbohydrates and has no impact on blood glucose levels. This makes it a suitable alternative for those who need to keep their sugar levels in check. Moreover, using Stevia can help diabetic individuals enjoy sweet foods and beverages without the fear of negatively affecting their health. The zero-calorie aspect of Stevia also contributes to maintaining a healthier weight, which is a crucial factor in managing diabetes.
Nutritional and Health BenefitsIn addition to its zero-calorie feature, Stevia also offers several nutritional and health benefits. Some research suggests that Stevia may help in lowering blood pressure and improving cholesterol levels. These potential benefits make Stevia not just a sugar substitute, but a supplement that can contribute to overall well-being.
Antioxidant PropertiesStevia leaves are rich in antioxidants, which help to combat oxidative stress in the body. Oxidative stress is linked to various chronic diseases, including heart disease and cancer. By incorporating Stevia into your diet, you might benefit from its antioxidant content, aiding in the reduction of inflammation and promoting better health.
Culinary UsesStevia is versatile and can be used in a variety of culinary applications. It’s available in different forms such as powders, liquid extracts, and even whole leaves. You can use Stevia to sweeten beverages like tea and coffee, baked goods, desserts, and even savory dishes that require a touch of sweetness. However, due to its high sweetness level, it is recommended to start with a small amount and adjust according to taste. Keep in mind that Stevia might behave differently than sugar in recipes, particularly in baking. Sugar contributes to the texture and volume of baked goods, while Stevia does not. Therefore, recipes using Stevia may require additional adjustments for the best results.
Economic and Environmental ImpactGrowing and harvesting Stevia can be advantageous from both economic and environmental perspectives. Stevia plants require less land and water compared to sugar cane or beet crops, making it a more sustainable option in the long run. Additionally, Stevia farming can provide economic opportunities for communities in developing countries where the plant is grown.
Are You Ready For a Zero-Calorie Sweetener?Stevia stands out as an exceptional zero-calorie sweetener, especially beneficial for those managing diabetes and looking to reduce their calorie intake. Its natural origin, coupled with its impressive sweetness and array of health benefits, make it a compelling alternative to traditional sugar and artificial sweeteners. Whether you are looking to alter your dietary habits or manage a health condition like diabetes, Stevia offers a promising solution for a healthier sweetening choice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6610) The History of Stevia: From Ancient Sweet Leaf to Global Sweetener
Date:
May 31, 2024 11:05 AM
The History of Stevia: From Ancient Sweet Leaf to Global SweetenerStevia, a natural sweetener that has become globally popular in recent years, boasts a rich history spanning centuries. This article delves into the origins and historical significance of stevia, shedding light on its traditional use by indigenous peoples and its evolution into a mainstream alternative to sugar.
The Origins of SteviaStevia, scientifically known as Stevia rebaudiana, originates from South America. This small, green plant is part of the Asteraceae family, which also includes daisies and sunflowers. The leaves of the stevia plant contain sweet compounds known as steviol glycosides, which are responsible for its sweetness.
Traditional Use by the Guaraní PeopleThe historical journey of stevia begins with the Guaraní people of Paraguay and Brazil, who have used the plant for over 1,500 years. The Guaraní referred to stevia as "ka'a he'ê," which translates to "sweet herb." They traditionally used stevia leaves to sweeten beverages like yerba maté, a popular herbal tea, and to enhance the flavor of various traditional dishes. Stevia wasn't just a sweetener for the Guaraní; it also held medicinal importance. The leaves were used to treat a variety of conditions, including burns, stomach issues, and as a general tonic. This dual use of stevia as both a sweetener and a medicinal plant highlights its invaluable role in indigenous culture.
Stevia's Journey to the Modern WorldRediscovery by European ExplorersThe modern history of stevia began in the 16th century when European explorers first arrived in South America. Spanish botanist and physician Pedro Jaime Esteve (1500–1556) is often credited with the early European studies on stevia, although the plant was not widely documented until later. Interest in stevia grew in the early 20th century when it was scientifically studied by Paraguayan chemist Ovidio Rebaudi. Rebaudi analyzed the sweet properties of stevia leaves and confirmed that they were much sweeter than sugar, which caught the attention of the scientific community.
Introduction to Asia and BeyondIn the 1970s, stevia began gaining traction in Japan as the country sought alternatives to artificial sweeteners. Japanese researchers developed methods for extracting and refining steviol glycosides from stevia leaves, making it possible to use stevia as a commercial sweetener. The success of stevia in Japan set the stage for its global acceptance.
Stevia in the Modern Health MovementHealth Benefits and AdvantagesStevia's rise in popularity can be attributed to its myriad of health benefits. Unlike sugar, stevia is calorie-free, making it an attractive option for those managing their weight. Additionally, stevia has a negligible effect on blood glucose levels, which is beneficial for individuals with diabetes or those monitoring their carbohydrate intake. Moreover, steviol glycosides are stable at high temperatures, making stevia a versatile sweetener suitable for cooking and baking. This thermal stability, combined with its natural origin, has positioned stevia as a preferred option for health-conscious consumers.
Regulatory Approval and Global AdoptionThe journey of stevia to becoming a global sweetener has involved rigorous scientific scrutiny and regulatory approval. In 2008, the United States Food and Drug Administration (FDA) granted stevia the status of "Generally Recognized As Safe" (GRAS), which paved the way for its use in a wide range of food and beverage products. Following the FDA's approval, other countries, including those in the European Union, Canada, and Australia, also approved the use of stevia in food and beverages. Today, stevia is found in everything from soft drinks to baked goods, reflecting its widespread acceptance and global reach.
Challenges and Future ProspectsOvercoming ObstaclesDespite its many advantages, the path to widespread adoption of stevia has not been without challenges. One of the initial hurdles was the aftertaste associated with some of the early stevia extracts. However, advances in extraction and formulation techniques have significantly improved the taste profile of stevia, making it more palatable for consumers. Another challenge has been ensuring the sustainable cultivation of stevia. As demand grows, it is essential to implement agricultural practices that support environmental sustainability and fair labor conditions for farmers.
Research and InnovationThe future of stevia holds exciting possibilities as ongoing research continues to explore new applications and improvements. Scientists are currently investigating the potential of stevia extracts in providing health benefits beyond sweetness, such as their antioxidant properties and possible roles in managing certain health conditions. Innovations in biotechnology are also paving the way for the development of new stevia varieties with enhanced sweetness and improved agronomic traits. These advancements could further solidify stevia's position as a key player in the global sweetener market.
In SummaryThe history of stevia is a fascinating journey from the rainforests of South America to the shelves of supermarkets around the world. From its traditional use by the Guaraní people to its rediscovery by European explorers and subsequent global adoption, stevia has proven to be a remarkable sweetener with enduring significance. As the modern world continues to prioritize health and wellness, stevia's natural sweetness offers a much-needed alternative to sugar, promising a future where we can enjoy the sweetness of life without compromising our health.
Are You Ready to Make a Sweet Change?If you've been searching for a healthier way to satisfy your sweet tooth, the journey of stevia offers a compelling reason to make the switch. With its rich history rooted in traditional use by the Guaraní people, and its scientifically-backed benefits recognized globally, stevia stands out as a truly remarkable sweetener. Free from calories and gentle on blood glucose levels, it's an excellent choice for both weight management and diabetes care. Plus, its versatility in cooking and baking means you won't have to compromise on your favorite recipes. Join the growing number of health-conscious consumers who are choosing stevia for a naturally sweet life. Explore its various forms—from whole leaves to refined steviol glycosides—and incorporate this natural sweetener into your diet today. Embrace the future of sweetening and enjoy the benefits of stevia for yourself and your loved ones.
Frequently Asked Questions (FAQ) About SteviaWhat is stevia?Stevia is a natural sweetener derived from the leaves of the Stevia rebaudiana plant, which is native to South America. It has been used for centuries by the Guaraní people and is known for being much sweeter than sugar while containing zero calories.
How is stevia used as a sweetener?Stevia can be used in various forms, including whole leaves, powdered extracts, and liquid concentrates. It is commonly used to sweeten beverages, baked goods, and other foods. Thanks to its stability at high temperatures, stevia can also be used in cooking and baking.
Is stevia safe to consume?Yes, stevia is considered safe for consumption. The United States Food and Drug Administration (FDA) has granted stevia the status of "Generally Recognized As Safe" (GRAS). It has also been approved for use in many other countries, including those in the European Union, Canada, and Australia.
Can stevia help with weight management?Stevia can be an effective tool for weight management because it contains no calories. Replacing sugar with stevia in your diet can help reduce overall calorie intake, which may contribute to weight loss or maintenance.
Is stevia suitable for people with diabetes?Stevia is suitable for people with diabetes as it has a negligible effect on blood glucose levels. This makes it a preferable alternative to sugar for those needing to monitor their carbohydrate intake. However, it is always best to consult with a healthcare provider before making any significant changes to your diet.
Does stevia have any side effects?Stevia is generally well-tolerated and considered safe for most people. However, some individuals may experience mild side effects, such as digestive discomfort, when consuming large amounts. It is advisable to use stevia in moderation.
What does stevia taste like?Stevia is known to be much sweeter than sugar, and its taste can vary depending on the form used and the specific product. Early versions of stevia extracts were noted for having a slight aftertaste, though modern formulations have significantly improved the taste profile.
How is stevia cultivated?Stevia is typically grown in subtropical and tropical climates. Sustainable cultivation practices are essential as the demand for stevia increases. These practices include using environmentally friendly agricultural methods and ensuring fair labor conditions for farmers.
Are there any environmental benefits to using stevia?Stevia has the potential to be more sustainable than traditional sugar crops. It requires less land and water to produce the same level of sweetness, which can reduce the environmental impact associated with sugar cultivation.
Can stevia be used in baking?Yes, stevia can be used in baking due to its high-temperature stability. However, because it is much sweeter than sugar, recipes may need to be adjusted to account for its intensity. Many commercially available stevia sweeteners come with specific usage guidelines for cooking and baking.
Are there different types of stevia products?Yes, stevia products come in various forms, including whole leaves, powdered extracts, and liquid concentrates. Some products are blended with other sweeteners or filler ingredients to better mimic the taste and texture of sugar.
How does stevia compare to artificial sweeteners?Stevia is a natural sweetener, which sets it apart from many artificial sweeteners. It is derived from a plant and does not undergo extensive chemical processing. Many consumers prefer stevia because it is perceived as a more natural and healthier option.
What research is being done on stevia?Ongoing research on stevia explores its potential health benefits beyond sweetness, such as its antioxidant properties and possible roles in managing certain health conditions. Innovations in biotechnology are also working to develop new stevia varieties with enhanced sweetness and other desirable traits.
Where can I buy stevia?Stevia products are widely available at VitaNet LLC. Stevia can be found in the baking aisle or the section dedicated to natural and alternative sweeteners. By understanding the benefits and uses of stevia, you can make an informed decision about incorporating this natural sweetener into your diet. With its rich history, proven health benefits, and versatility, stevia offers a compelling alternative to traditional sugar.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6607) Debunking Myths About Stevia: Separating Fact from Fiction
Date:
May 29, 2024 05:02 PM
Debunking Myths About Stevia: Separating Fact from FictionStevia has gained significant popularity as a natural sweetener, but with popularity comes a wave of misconceptions and myths. As consumers become more health-conscious and seek alternatives to sugar, it’s essential to separate fact from fiction regarding Stevia. This article debunks stevia myths with evidence-based info to clarify consumer doubts.
Myth 1: Stevia Is ArtificialFact:One of the most prevalent myths about stevia is that it is artificial. In reality, stevia is a completely natural sweetener derived from the leaves of the Stevia rebaudiana plant. The plant has been used for centuries by indigenous people in South America for its sweetening properties. Unlike artificial sweeteners such as aspartame or saccharin, stevia is derived from a natural source and processed to extract its sweet components, known as steviol glycosides.
Myth 2: Stevia Is HarmfulFact:Another common misconception is that stevia is harmful to health. Scientific studies and regulatory organizations have repeatedly confirmed the safety of stevia. The Food and Drug Administration (FDA) classifies high-purity stevia extracts as "Generally Recognized as Safe" (GRAS) for consumption. Furthermore, research indicates that stevia can have health benefits like lowering blood pressure and blood sugar levels, making it a suitable sweetener for individuals with diabetes and hypertension.
Myth 3: Stevia Tastes BadFact:Some people believe that stevia has a bitter aftertaste, which makes it less appealing as a sweetener. While early formulations of stevia extracts indeed presented a noticeable bitter aftertaste, advancements in processing have minimized this issue. Modern high-purity stevia products are often combined with other natural sweeteners or flavor enhancers to improve taste, making them virtually indistinguishable from sugar in many applications.
Myth 4: Stevia Is Only for DiabeticsFact:While it’s true that stevia is an excellent sweetener for individuals managing diabetes due to its zero-calorie and zero-carbohydrate nature, it is not exclusive to them. Anyone looking to reduce sugar consumption or seeking a natural alternative can benefit from using stevia. It is a versatile sweetener that can be used in a variety of foods and beverages, making it suitable for the general population striving for a healthier lifestyle.
Myth 5: All Stevia Products Are the SameFact:Not all stevia products are created equal. The purity and quality of stevia extracts can vary significantly between products. It's crucial to read labels and choose products that contain high-purity stevia extracts, as some products on the market contain added fillers or lower-grade stevia. By selecting reputable brands and scrutinizing ingredient lists, consumers can ensure they are using high-quality stevia that meets their health standards. Kal Sure Stevia Extract is one of those high-quality brands that stand out in the market. Known for its commitment to purity and potency, Kal Sure Stevia Extract offers a product that is free from fillers and unnecessary additives. The brand’s stringent quality control measures ensure that each batch contains only high-purity stevia extracts, delivering consistent sweetness without the aftertaste. Consumers can trust Kal Sure Stevia Extract as a safe, reliable, and pleasant-tasting alternative to conventional sugar. When choosing a stevia product, it's essential to opt for a brand like Kal Sure stevia to enjoy the full benefits of this natural sweetener.
Myth 6: Stevia Causes Allergic ReactionsFact:Some believe that consuming stevia can trigger allergies. However, stevia is generally considered hypoallergenic and does not commonly cause allergic reactions. There have been few documented cases of stevia allergies, and these are typically related to individuals with specific sensitivities. For the vast majority of people, stevia is a safe and well-tolerated sweetener, even for those with common food allergies.
Myth 7: Stevia Leads to Weight GainFact:The notion that stevia contributes to weight gain is counterintuitive, given its zero-calorie nature. Unlike sugar, which is high in calories and contributes to weight gain, stevia provides sweetness without adding calories. Using stevia instead of sugar can help reduce overall caloric intake, aiding in weight management efforts. Multiple studies have shown that replacing sugar with stevia can be an effective strategy for achieving and maintaining a healthy weight.
Myth 8: Stevia Disrupts MetabolismFact:Concerns about stevia disrupting metabolism are unfounded. Research indicates that stevia neither affects metabolic rates nor alters insulin sensitivity in a negative manner. On the contrary, stevia has been shown to have a neutral or even beneficial impact on metabolism, particularly for individuals with metabolic disorders like diabetes. It allows for sweetening without the metabolic consequences associated with high sugar consumption.
Myth 9: Stevia Can’t Be Used in BakingFact:There is a misconception that stevia is unsuitable for baking due to its chemical composition. While it is true that baking with stevia requires some adjustments—since it does not have the same physical properties as sugar—it can still be used effectively. Bakers often use stevia in combination with other ingredients to achieve the desired texture and sweetness. Many recipes and commercial products have successfully incorporated stevia, proving its versatility in baking applications.
Myth 10: Stevia Is ExpensiveFact:Consumers sometimes think that switching to stevia will significantly increase their grocery bills. While high-purity stevia products may be more expensive per ounce than sugar, they are much sweeter. A small amount of stevia goes a long way, which means that even a small container can last a long time. In the long run, the cost of stevia can be comparable to or even less than sugar, particularly when considering the health benefits and potential medical cost savings from reduced sugar consumption. Brands like Kal Stevia 3.5 oz contains 1800 servings per container.
Are You Ready to Sweeten Your Life?It is crucial to approach any information about stevia with a critical eye and rely on evidence-based data rather than myths. Stevia is a natural, safe, and versatile sweetener that offers numerous health benefits without the downsides of sugar and artificial sweeteners. By debunking these common misconceptions, consumers can make informed choices that contribute to a healthier lifestyle.
Take the Next Step Towards a Healthier LifeNow is the perfect time to reconsider your sweetening choices and embrace the benefits of stevia. With its proven safety, versatility in cooking, and numerous health advantages, stevia stands out as a superior alternative to traditional sugar and artificial sweeteners. Start exploring reputable brands, like Kal Sure Stevia Extract, and experiment with incorporating stevia into your daily routine. By making this simple switch, you can enhance your overall well-being without compromising on taste. Visit your local grocery store or trusted online retailer to find high-quality stevia products and embark on your journey to a healthier, sweeter life today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6605) Magma Plus: The Power of Fruits and Veggies in a Drink
Date:
May 24, 2024 02:51 PM
Magma Plus: The Power of Fruits and Veggies in a DrinkImagine if you could get all your daily fruits and vegetables in just one drink. Magma Plus is a fruit and veggie powder supplement designed to provide natural energy and boost overall health. This drink mix, made from barley grass juice powder and 57 other natural ingredients, is a convenient way to get many essential nutrients all in one go. Magma Plus gives your body the vitamins, minerals, and antioxidants it needs for energy, immunity, and more.
What Is In it?Magma Plus is a dietary supplement that is rich in active enzymes, antioxidants, vitamins, minerals, amino acids, protein, and chlorophyll. Dr. Yoshihide Hagiwara discovered that "young barley grass is one of the most nutritionally balanced foods in nature." With this in mind, the creators of Magma Plus added barley grass juice powder along with a blend of other nutritious fruits, vegetables, plants, and herbs to create a potent energy drink. The product is available in two sizes: 150 grams (16 servings) and 300 grams (33 servings). Each serving contains 1.8 grams of barley grass juice extract, making it a nutrient-dense option for anyone looking to improve their daily nutrition.
Why Choose Magma Plus?Unlike many energy drinks that rely on sugar and caffeine, Magma Plus is a natural booster that contains important nutrients for energy production. It is packed with various fruit and vegetable extracts, including Siberian ginseng and barley grass. These ingredients energize you without the crash that often comes with caffeinated drinks. Some of the key benefits include:
IngredientsHere is a list of the natural ingredients found in Magma Plus:
Health BenefitsMagma Plus provides various health benefits:
How to Use Magma PlusIt's simple to add Magma Plus to your daily routine. Just stir three teaspoons into an 8 oz. glass of water or your favorite juice. Be sure not to mix it with hot liquids, as heat can neutralize the active enzymes. For best results, take it once or twice daily on an empty stomach, about 20 minutes before meals.
Customer TestimonialsDon't just take our word for it. Here are what some of our satisfied customers have to say:
Research and SourcesScientific studies support the benefits of many of the ingredients found in Magma Plus. Research shows that barley grass is rich in vitamins, minerals, and antioxidants that can help improve health. Studies have also shown the benefits of ginseng, Echinacea, and other herbs in boosting energy and immunity.
Brand InformationGreen Foods Corp., the company behind Magma Plus, has been in the health food business for many years. They are committed to providing high-quality, natural products that support a healthy lifestyle. Their gentle, temperature-controlled processing techniques ensure that the nutrients in Magma Plus remain intact and effective.
Are You Looking for Convenience When Consuming Fruits and Veggies?If you're looking for a convenient, natural way to boost your energy and support your overall health, Magma Plus is an excellent choice. With its unique blend of fruits, vegetables, and herbs, it provides a multitude of nutrients in each serving. Try Magma Plus today and experience the benefits for yourself! Buy Magma Plus Now!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6600) The Benefits of Horse Chestnut Extract
Date:
October 25, 2022 04:43 PM
Horse chestnut extract is a popular ingredient in European herbalism. It has many active constituents, including saponins and flavones, which have been scientifically shown to support the integrity of the vascular system and connective tissue.* Rutin, a powerful free radical scavenger, has been added to complete this formula.* Horse chestnut helps support healthy vascular system. What is Horse Chestnut? Horse chestnut is an flowering plant that is native to the Balkans. The tree can grow up to 30m tall and flowers in early summer. The fruit is a glossy brown nut that contains saponin. The Benefits of Horse Chestnut Horse chestnut extract is rich in saponins, flavones, and tannins, which are all substances that have been shown to support the health of the vascular system.* In addition, horse chestnut extract also contains rutin, a potent antioxidant.* Together, these nutrients work to help maintain healthy circulation and support the structure of connective tissue.* How to Use Horse Chestnut Extract Horse chestnut extract can be found in capsules or liquid extracts. For best results, follow the dosage instructions on the product label. Rutin and its potential benefits Rutin is a phytochemical that can be found in a wide variety of plants. Rutin-rich foods include apples, blackberries, buckwheat, chokeberries, cranberries, fonts, grapefruit, lemons, limes, onions, oranges, pineapples, tangerines, and many more. This nutrient is known for its anti-inflammatory properties and has been linked to a number of potential health benefits. Some of the potential benefits associated with rutin intake include:
While research on the effects of rutin is ongoing, there is some preliminary evidence to suggest that this nutrient could offer a wide range of health benefits. If you are looking for an herbal supplement to support healthy circulation and connective tissue, consider horse chestnut extract.* This potent formula contains saponins, flavones, tannins, and rutin—all of which have been shown to support vascular health.* Try horse chestnut extract today and see for yourself how this herb can help you maintain optimal health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6525) Gymnema Sylvestre - An Herb That Promotes Healthy Glucose Metabolism
Date:
October 25, 2022 02:41 PM
Gymnema sylvestre is an herb that has been used traditionally in India for centuries. Modern research has shown that this herb may help to support healthy glucose metabolism through its ability to promote healthy pancreatic function.* In addition, gymnema exhibits potent free-radical scavenging properties.* NOW® Gymnema Sylvestre Extract is standardized to gymnemic acids, which are the compounds that have been identified as its bioactive constituents.* Gymnema sylvestre is a woody climbing shrub that grows in the tropical forests of central and southern India. The leaves of the plant have been used traditionally in Ayurvedic medicine for centuries.1 Modern science has validated many of the traditional uses for this herb and has identified several key active components.2-4 Promotes Healthy Pancreatic Function* One of the traditional uses for Gymnema sylvestre was to support healthy glucose metabolism.5 This effect was thought to be due to the herb’s ability to promote healthy pancreatic function.* The primary active components in Gymnema sylvestre – gymnemic acids – have been shown in animal studies to increase insulin secretion from the pancreas.6,7 In addition, these compounds appear to help maintain healthy beta cell function and architecture.8,9 Maintenance of normal beta cell function is critical for long-term metabolic health since these cells are responsible for producing insulin in response to rising blood sugar levels.10,11 Exhibits Potent Free-Radical Scavenging Properties* In addition to supporting healthy pancreatic function, recent research has shown that Gymnema sylvestre extracts also possess potent free-radical scavenging properties.*12 These effects were attributed primarily to the gymnemic acids present in the herb.13 This natural free-radical scavenging activity may help support cellular health.* NOW® Gymnema Sylvestre Extract is standardized to a minimum of 25% gymnemic acids and provides 6:1 extract potency. For easy supplementation, take 2 capsules 1 or 2 times daily with food or water. In Summary: Gymnema sylvestre is an herb with a long history of use in Ayurvedic medicine. Modern science has validated many of the traditional uses for this herb and has identified several key active components, including gymnemic acids which have been shown in animal studies to increase insulin secretion from the pancreas. Additionally, extracts of Gymnema sylvestre have been shown to possess potent free-radical scavenging properties which may help support cellular health.* NOW® Gymnema Sylvestre Extract is standardized to a minimum of 25% gymnemic acids and provides 6:1 extract potency. For easy supplementation, take 2 capsules 1 or 2 times daily with food or water.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6523) D-Flame - Herbal Support for a Healthy Response to Stress
Date:
October 07, 2022 10:26 AM
Feeling stressed? You're not alone. In today's fast-paced world, it's more important than ever to find natural ways to support our bodies in responding to stress. Introducing D-Flame, a carefully crafted blend of herbal extracts that may help to support a healthy response to physiological stress. Read on to learn more about the key ingredients in D-Flame and how they work together to keep your body operating at its best. The Science Behind D-Flame D-Flame contains a unique blend of botanical extracts that work together to support the body's natural response to stress. Here's a closer look at some of the key ingredients in D-Flame and how they contribute to its ability to promote a healthy stress response: Holy Basil Extract - Holy basil is an ayurvedic herb that has been used for centuries in India for its many purported health benefits. Among these is the ability to help the body adapt to stress by supporting the activity of key stress mediators. Ursolic Acid - Ursolic acid is a type of triterpenoid compound that is found in a variety of plants. It has been shown to possess anti-inflammatory and antioxidant properties, which may help to protect cells from damage caused by oxidative stress. Turmeric Extract - Turmeric is a well-known spice with powerful antioxidant activity. Its active ingredient, curcumin, has been shown to modulate the activity of enzymes involved in inflammation, helping to keep inflammation levels in check. Ginger Extract - Ginger has long been used as a natural remedy for digestive issues like nausea and indigestion. It also possesses potent anti-inflammatory activity, which may help to reduce pain and swelling associated with occasional overexertion or injury. Green Tea Extract - Green tea is rich in antioxidants and polyphenols, which may help protect cells from damage caused by free radicals. It also contains caffeine, which has been shown to increase alertness and focus while also reducing fatigue. Boswellin® - Boswellin® is an extract of the herb boswellia serrata that has been shown to inhibit the production of pro-inflammatory molecules known as leukotrienes. This action helps to reduce inflammation throughout the body. Bromelain - Bromelain is an enzyme found naturally in pineapple that possesses powerful anti-inflammatory activity. It works by inhibiting the production of pro-inflammatory cytokines, helping to reduce inflammation and pain associated with conditions like joint pain and arthritis. Baikal Skullcap - Baikal skullcap is an herb native to Southeast Asia that has traditionally been used as a remedy for digestive issues and skin ailments. It also possesses potent anti-inflammatory activity, which makes it ideal for alleviating occasional pain and swelling associated with injury or overexertion. Resveratrol - Resveratrol is a type of phytonutrient that is found in grapes, berries, and other plant foods. It has strong antioxidant activity and has also been shown to modulate the activity of genes involved in inflammation, making it an effective tool for reducing chronic inflammation throughout the body.* Berberine - Berberine is a bitter alkaloid compound that is found in a variety of plants including goldenseal, barberry, and Oregon grape root. It has powerful antimicrobial activity against bacteria, viruses, and fungi.* Additionally, berberine has strong anti-inflammatory activity, making it ideal for alleviating occasional pain and swelling associated with injury or overexertion.* In Summary: D-Flame is an all-natural blend of botanical extracts that have been traditionally used for centuries to support the body's response to stress.* These herbs work together synergistically to modulate key enzymes and mediators involved in inflammation.* This action helps reduce chronic inflammation throughout the body.* Additionally, these herbs also help protect cells from damage caused by oxidative stress.* If you're looking for an herbal supplement to help support your body during times of stress, look no further than D-Flame!*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6487) D-Flame - Herbal Support for a Healthy Response to Stress
Date:
October 06, 2022 04:01 PM
Feeling stressed? You're not alone. In today's fast-paced world, it's more important than ever to find natural ways to support our bodies in responding to stress. Introducing D-Flame, a carefully crafted blend of herbal extracts that may help to support a healthy response to physiological stress. Read on to learn more about the key ingredients in D-Flame and how they work together to keep your body operating at its best. The Science Behind D-Flame D-Flame contains a unique blend of botanical extracts that work together to support the body's natural response to stress. Here's a closer look at some of the key ingredients in D-Flame and how they contribute to its ability to promote a healthy stress response: Holy Basil Extract - Holy basil is an ayurvedic herb that has been used for centuries in India for its many purported health benefits. Among these is the ability to help the body adapt to stress by supporting the activity of key stress mediators. Ursolic Acid - Ursolic acid is a type of triterpenoid compound that is found in a variety of plants. It has been shown to possess anti-inflammatory and antioxidant properties, which may help to protect cells from damage caused by oxidative stress. Turmeric Extract - Turmeric is a well-known spice with powerful antioxidant activity. Its active ingredient, curcumin, has been shown to modulate the activity of enzymes involved in inflammation, helping to keep inflammation levels in check. Ginger Extract - Ginger has long been used as a natural remedy for digestive issues like nausea and indigestion. It also possesses potent anti-inflammatory activity, which may help to reduce pain and swelling associated with occasional overexertion or injury. Green Tea Extract - Green tea is rich in antioxidants and polyphenols, which may help protect cells from damage caused by free radicals. It also contains caffeine, which has been shown to increase alertness and focus while also reducing fatigue. Boswellin® - Boswellin® is an extract of the herb boswellia serrata that has been shown to inhibit the production of pro-inflammatory molecules known as leukotrienes. This action helps to reduce inflammation throughout the body. Bromelain - Bromelain is an enzyme found naturally in pineapple that possesses powerful anti-inflammatory activity. It works by inhibiting the production of pro-inflammatory cytokines, helping to reduce inflammation and pain associated with conditions like joint pain and arthritis. Baikal Skullcap - Baikal skullcap is an herb native to Southeast Asia that has traditionally been used as a remedy for digestive issues and skin ailments. It also possesses potent anti-inflammatory activity, which makes it ideal for alleviating occasional pain and swelling associated with injury or overexertion. Resveratrol - Resveratrol is a type of phytonutrient that is found in grapes, berries, and other plant foods. It has strong antioxidant activity and has also been shown to modulate the activity of genes involved in inflammation, making it an effective tool for reducing chronic inflammation throughout the body.* Berberine - Berberine is a bitter alkaloid compound that is found in a variety of plants including goldenseal, barberry, and Oregon grape root. It has powerful antimicrobial activity against bacteria, viruses, and fungi.* Additionally, berberine has strong anti-inflammatory activity, making it ideal for alleviating occasional pain and swelling associated with injury or overexertion.* In Summary: D-Flame is an all-natural blend of botanical extracts that have been traditionally used for centuries to support the body's response to stress.* These herbs work together synergistically to modulate key enzymes and mediators involved in inflammation.* This action helps reduce chronic inflammation throughout the body.* Additionally, these herbs also help protect cells from damage caused by oxidative stress.* If you're looking for an herbal supplement to help support your body during times of stress, look no further than D-Flame!*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6486) The Many Benefits of Black Cohosh Root
Date:
September 14, 2022 01:52 PM
Black Cohosh Root is a plant that has been historically used by Native American women. Current scientific research shows that Black Cohosh Root may help support a healthy response to the natural changes occurring during menopause.* NOW® Black Cohosh Root also includes Licorice Root and Dong Quai, which have enjoyed widespread popularity in Asia for centuries, especially among middle aged women. In this blog post, we'll explore the many benefits of Black Cohosh Root and how it can help support your health during menopause. Historical Use of Black Cohosh Root among Native American Women Black Cohosh Root has been used by Native American women for centuries. In fact, it is sometimes referred to as "the female herb" due to its long history of use for supporting female health. Traditional uses of Black Cohosh Root include easing the discomforts associated with menstruation and menopause, such as hot flashes and night sweats.* Current Scientific Research on Black Cohosh Root Recent scientific research has shown that Black Cohosh Root may help support a healthy response to the natural changes occurring during menopause.* This is likely due in part to the plant's ability to mimic the effects of certain hormones in the body. Additionally, Black Cohosh Root is a rich source of phytoestrogens, which are plant-based compounds that may help offset some of the decline in estrogen levels that occurs during menopause. Studies have shown that taking Black Cohosh Root regularly can help reduce hot flashes and night sweats by up to 50%!* The Many Benefits of Black Cohosh Root In addition to its historical use among Native American women and current scientific research showing its efficacy for supporting menopausal health, there are many other benefits of taking Black Cohosh Root. For example, Black Cohosh Root has also been traditionally used for relieving anxiety, nervousness, and tension.* Additionally, animal studies have shown that extracts of Black Cohosh Root may help support healthy cholesterol levels already within the normal range.* If you're looking for an all-natural way to support your health during menopause, black cohosh root may be right for you! If you're looking for an all-natural way to support your health during menopause, black cohosh root may be right for you! With a long history of use among Native American women and current scientific research showing its efficacy for supporting menopausal health, there are many reasons to give black cohosh root a try. Talk to your healthcare provider today about whether black cohosh root is right for you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6449) The Health-Supporting Properties of Curcumin
Date:
September 14, 2022 11:19 AM
Curcumin, the active polyphenolic extract of turmeric, is one of the most scientifically investigated plant compounds. Curcumin's health-supporting properties depend on its bioavailability. NOW Curcumin Phytosome is a unique form of curcumin complexed with phosphatidylcholine that clinically demonstrates enhanced absorption and bioavailability as compared with standard curcumin extracts. Clinical studies also show that curcumin phytosome is a powerful free radical scavenger, can help to support a balanced immune system response to normal metabolic stress, and can promote healthy joint mobility and flexibility. The Benefits of Curcumin Curcumin has been shown to offer a wide range of health benefits, thanks to its potent antioxidant and anti-inflammatory properties.* Some of the ways in which curcumin supports health include: Brain Health: Curcumin has been shown to promote cognitive function and healthy brain aging.* It does this by reducing inflammation and oxidative stress, two factors that are known to contribute to age-related cognitive decline.* Heart Health: Curcumin has been shown to support cardiovascular health by helping to maintain healthy cholesterol levels already within the normal range.* It also promotes healthy blood vessel function.* Digestive Health: Curcuin supports a healthy inflammatory response in the digestive tract.* This helps to keep the gut lining healthy and promote regularity.* In conclusion, curcumin is a powerhouse compound with numerous health-supporting properties. Thanks to its unique formulation as a complex with phosphatidylcholine, NOW Curcumin Phytosome is one of the most bioavailable forms of curcumin on the market today. If you're looking for a supplement to support brain, heart, and digestive health, look no further than curcumin phytosome!*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6447) What is Curcumin ?
Date:
August 06, 2021 03:34 PM
Curcumin is a yellow pigment found in the turmeric plant of the ginger family, a popular spice used in curry. It is a polyphenol with anti-inflammatory properties and the ability to increase the amount of antioxidants produced in the body. Curcumin and its curcuminoids are contained in turmeric extracts, which are produced to supplement the high efficacy of the spice. Turmeric is a herb from the ginger family and is used in India, Asia and Central America to enhance the color and flavor of foods. Turmeric has various medical benefits associated with its active ingredient curcumin. One of the main claims of turmeric is that it is used to combat inflammation, but most of its anti-inflammatory power is attributed to curcumin. Curcumin is used in many different forms and has several potential health benefits. Below we outline some of the many potential benefits of turmeric and turmeric. It is the safe and effective alternative to OTC drugs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6382) Curcumin and Grapeseed
Date:
September 01, 2020 11:03 AM
Smoking, Chemical exposure, pesticides, nutrient deficiencies, to much sun exposure, and over the counter drugs and prescriptions can cause cancer. In the news, there are forever chemical roundup found in our water supply, it is no wonder we are laden with cancer as a society. Fortunately, a healthy cancer preventing diet along with natural plant compounds can be far more effective and cost a lot less than conventional care alone. Two top suggested natural medicines available right now are curcumin and grape seed extract. These two herbs are an amazing pair, curcumin is a fat soluble herb to fight oxidation on the fatty oil side in the body and grape seed extract is water soluble, making it a great antioxidant to fight oxidative stress on the water side of a cell. Cells in the body are made up of oil(fats) and water. The impact of both together on your health is virtually miraculous. Curcumin neutralizes unstable free radicals that take electrons from nearby molecules, and stop them from creating a cascade of damaged cells. It also reduces inflammation reduces inflammation markers in the body to prevent prevent tissue degradation. Curcumin has been shown to stop the changes that happen from free radical damage causing normal cells to become cancerous, and tumorous formations, and can even stop cancer from metastasizing or migrating to other parts of the body. Published studies anticancer activity have found that it can suppress breast, prostate, liver, skin, colon and lung cancer cells. Curcumin Must Be Absorbed To Be Useful One of the challenges or using curcumin for cancer prevention and treatment is that not all curcumin extracts are easily absorbable into the body. Blending curcumin in Turmeric essential oil enhances absorption and provides the additional benefits of ar-turmerone, a compound in the oil. Curcumin Makes Chemo More Effective There is big potential for curcumin when used with conventional treatment. BCM-95 curcumin, through research, has shown to sensitize human colon cancer cells to chemotherapy treatment where it would otherwise be resistant to this form of treatment. In some cases tumor recurrence rates can be as high as 60% but when treated with curcumin while under conventional treatment, curcumin boosted the effectiveness of the chemo drug 5-fluorouracil against cancer stem cells. Curcumin has great potential in conjunction with conventional cancer treatment and recovery. It has been found that as chemo treatment progresses, cancer cells become resistant to the chemo treatment and the dosage has to be increased as the treatment continues increasing the toxic side effects. Fortunately, curcumin taken in conjunction with conventional cancer treatment can improve the effectiveness of chemo and so the dosage can be lowered reducing the toxic side effects for individuals. This is good news! Curcumin Protects The Body During Cancer Treatment In a clinical study with curcumin, it showed to alleviate side effects of one of the most common treatments of prostate cancer known as external beam radiotherapy (EBRT) where the doctor uses radiation to destroy tumorous cancel cells. This sort of therapy has many side effects making it a difficult therapy for most men. I often causes sexual dysfunction, digestive problems, urinary tract pain and loss of control. The higher the radiation dosage the more effective the treatment is but this causes significant discomfort, that is why most doctors lean towards lower dosages which makes the treatment less effective. The clinical study administered 3000mg of BCM-95 curcumin that is 1000mg x 3 per day or a placebo one week before therapy started and during the treatment length. Each capsule of curcumin contained curcuminoids, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oil of turmeric, this is a full spectrum curcumin supplement. At the end of the treatment which lasted 20 weeks the most dramatic difference between the two groups in the study was urinary symptoms. The curcumin group said a 50% decrease in symptoms or side effects of the radiation. Also, researchers noted that the curcumin did not reduce the efficacy of the EBRT.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6362) Study identifies a natural preservative in the arjun tree
Date:
May 17, 2019 03:56 PM
Terminalia arjuna has been studied closely by researchers from India and New Zealand. Commonly known as the arjun tree, this plant was used on chevon sausages to test the properties of preservation. The study suggest that the it produced significantly lower values for total plate count, psychrophilic count, yeast and mold count, and free fatty acid values. The results showed an improved lipid oxidative stability and storage quality while refrigerated, thus suggesting that the arjun tree can be a novel natural meat preservative. Key Takeaways:
"Researchers from India and New Zealand explore the potential of Terminalia arjuna as a novel natural preservative in meat products." Read more: https://www.naturalnews.com/2019-04-09-study-identifies-a-natural-preservative-in-the-arjun-tree.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6329) Study: Astragalus can improve symptoms of pulmonary arterial hypertension
Date:
May 10, 2019 02:20 PM
Astragalus is known in Chinese medicine because it has been used by the Chinese for centuries as a medicinal herb. Recent researchers have backed up the healing claims of the plant. In a new study that was done in China, Chinese researchers have discovered that polysaccharide extracts from astragalus can be effective against pulmonary arterial hypertension. To carry out the study they fed rats with monocrotaline in order to induce pulmonary arterial hypertension in them. Then they gave the rats 200 milligrams per kilogram of astragalus polysaccharides once in every two days for a period of two weeks. The results were positive. It was found that the polysaccharides of astragalus reduced the hypertension of the pulmonary artery induced by monocrotaline in rats. There were other benefits that were discovered. The treatment with the polysaccharide of astragalus also eliminated oxidative stress, promoted vasodilation, and reduced inflammation in the rats. All these suggest that astragalus lowers the blood pressure in individuals. The findings of the study were then published in the American Journal of Chinese Medicine with the authors stating that astragalus can be used to eliminate symptoms of pulmonary arterial hypertension in individuals. Key Takeaways:
"In China, astragalus is one of the herbs commonly prescribed to help with diabetes management. Research has also shown that the active compounds in astragalus may help in reducing blood sugar levels in people with Type 2 diabetes. Lab trials have shown that it improves metabolism, reduce blood sugar levels, and aid in weight loss." Read more: https://www.naturalnews.com/2019-04-17-astragalus-improves-symptoms-of-pulmonary-arterial-hypertension.html Even CBD can help reduce hypertension.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6305) Natural anxiety relief: Scientific study reveals how ashwagandha root can help
Date:
May 08, 2019 02:35 PM
The many health benefits of the ashwagandha root is well known to ayurvedic medicine. It is only recently that conventional medicine is becoming aware of this due to the increase in the number of published articles on the effectiveness of ashwagandha root. It is known that the ashwagandha root is a good adaptogen and it is prolific for combating stress, for giving support to the adrenal system, and also for help in balancing the hormones in the body. It can also serve as an exceptional herb for aiding sleep. This effect on the body is due to the richness of alkaloids including sioinidosides that can be found in ashwagandha root which makes it serve as a mild sedative for natural anxiety relief. A recent study in which 64 human subjects were used and half were given a placebo while the other half ashwagandha root extracts gave impressive results in showing that ashwagandha root extracts is effective for boosting resistance to stressors and can help adults suffering from chronic stress. Furthermore, there is no side effect with taking ashwagandha roots even if one is not feeling stress. Key Takeaways:
"This study further propels holistic medicine’s reach into the mainstream by confirming that ashwagandha root extract boosts resistance to stressors and can be safely utilized as an adaptogen for adults suffering from chronic stress issues." Read more: https://www.naturalhealth365.com/ashwagandha-root-anxiety-2908.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6283) Polysaccharide extract from reishi mushrooms found to have hypolipidemic, antioxidant, and antiapoptotic properties
Date:
May 08, 2019 01:29 PM
A recent study published in the Journal of Medicinal Food found that some properties of the Reishi Mushroom can fight obesity. The study was conducted by a Chinese research team at Hunan Agricultural University. It involved feeding mice high fat diets and then studying how the compounds of the mushrooms combated the weight gain over the course of a 12 week research project. The mushrooms exhibited helpful properties at both dosage levels that were tested. Key Takeaways:
"In mice, treatment with reishi mushroom polysaccharides, in both doses, significantly reduced the body weight increases caused by the feeding with a high-fat diet." Read more: https://www.naturalnews.com/2019-03-27-reishi-mushroom-hypolipidemic-antioxidant-antiapoptotic.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6280) Can reishi mushrooms help prevent cancer and other life-threateningdiseases?
Date:
May 03, 2019 03:59 PM
Reishi mushrooms and reishi extract have substantial health benefits, especially for boosting your immune system. Reishi mushrooms include a diverse array of bioactive compounds that, collectively, may boost cellular metabolism and restore the efficiency that the immune system tends to lose over time. Studies also indicate that reishi mushroom compounds may help induce immune cells to target cancer cells more aggressively, and boost the cancer-fighting functions of the spleen and thymus. Reishi mushrooms extracts may also help boost your overall immune system response against viruses and other pathogens. Key Takeaways:
"Reishi mushroom extracts can block the human immunodeficiency virus, hepatitis B virus, and other infectious microbes from compromising the health of the targeted organs." Read more: https://www.naturalnews.com/2019-03-28-can-reishi-mushrooms-help-prevent-cancer-and-other-life-threatening-diseases.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6250) Oat extract can protect against alcohol-induced liver damage
Date:
May 02, 2019 02:59 PM
Eating oats may prevent liver damage caused by drinking, according to research published in the journal Nutrition Research. Indian researchers tested the effects of oat extract on mice with alcohol-induced liver damage. First, they pretreated mice with phenolic-enriched ethyl acetate fraction of oats at two levels every day for 12 days. Next, they induced liver damage in the same mice with doses of 50 percent ethanol every 12 hours. Their results showed that pretreatment with oat extract at higher dosages decreased the levels of liver injury. Key Takeaways:
"Research has found an association between consumption of oats and lower risk of cardiovascular disease, diabetes, and gastrointestinal disorders." Read more: https://www.naturalnews.com/2019-03-13-oat-extract-can-protect-against-alcohol-induced-liver-damage.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6244) A species of hawthorn has been found to control abnormally highblood sugar levels
Date:
May 02, 2019 02:45 PM
A team of researchers from the Middle East have found that a species of hawthorn, Crete hawthorn, has the ability to lower elevated levels of glucose in the blood. They have published their findings in the journal BMC Complementary and Alternative Medicine. Along with its effects on blood glucose, called its anti-hyperglycemic property, it also has hyperlipidemic properties, that is, the ability to protect the body against high levels of fat such as cholesterol in the blood. They carried out the study using mice that were induced with hyperglycemia through feeding them alloxan. The mice were then divided into two groups, one group receiving Crete hawthorn extracts and the other given a chemical for control. They also used another animal model to understand its hyperlipidemic properties and to investigate whether the plant had antioxidant and antimicrobial properties. The results of the findings were that Crete hawthorn had important antioxidant properties due to its containing phenols and flavonoids. They also found that it had antimicrobial properties because it acted against bacteria such as E. Coli and Staphylococcus aureus, among others. Key Takeaways:
"The mice were then divided into groups, with some receiving an ethanol extract from Crete hawthorn leaves while others were given glibenclamide for positive control." Read more: https://www.naturalnews.com/2019-03-12-hawthorn-controls-high-blood-sugar-levels.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6243) Fenugreek reduces menopausal symptoms
Date:
May 02, 2019 01:55 PM
According to a study in Phytotherapy Research, the nutrient fenugreek may help ease the symptoms associated with menopause without the unpleasant side effects of traditional hormone replacement therapy. Study participants who consumed 1,000 milligrams of fenugreek extract daily reported a significant improvement in headaches, hot flashes, insomnia, and night sweats, as well as an overall improvement in quality of life. Researchers concluded that fenugreek extract is a safe and effective treatment alternative for menopausal women. Key Takeaways:
"Furthermore, the researchers found fenugreek extract treatment is safe and plays a role in the management of lipid profile in menopausal women." Read more: https://www.naturalnews.com/2019-03-15-fenugreek-reduces-menopausal-symptoms.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6238) Field elm bark protects against liver damage, gastric ulcers andhigh blood pressure
Date:
April 25, 2019 04:51 PM
Field elm, which is known for its health benefits, is now being touted for helping with blood pressure, gastric ulcers, and liver damage. Researchers in France and Algeria found that field elm acted as an antioxidant which relaxed the coronary artery and protected the stomach from ulcers and the liver from toxins. There are various types of elm, some are good for skin irritations, diarrhea, heartburn, sore throats, or cramps. The trees are known for their strong wood. Key Takeaways:
"The researchers also saw that the extract can protect the stomach from ulcers and protect the liver from toxic substances. In addition, the extract also exhibited a relaxing effect on the coronary artery." Read more: https://www.naturalnews.com/2019-03-12-field-elm-bark-protects-against-liver-damage.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6186) How eating bitter herbs can fix digestive system problems
Date:
April 24, 2019 02:01 PM
Gastroesophagael reflux disease (GERD) is a common, vexing and potentially serious condition, but bitter herbs can sometimes help reduce its severity. The “bitters” used by herbalists usually include extracts from a variety of different plants. While plants produce bitter tastes to deter animals (including humans) from eating them, that bitterness can also indicate high concentrations of antioxidants and other compounds with valuable health benefits. Bitters can trigger the digestion-stimulating hormone called gastrin, as well as the release of bile and enzymes that break down protein. Key Takeaways:
"However, appropriate amounts of edible bitter greens, spices and herbs can provide important health benefits, and should be included in the diet." Read more: https://www.naturalhealth365.com/bitter-herbs-digestive-system-2779.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6173) 12 Proven Health Benefits of Ashwagandha
Date:
April 23, 2019 02:37 PM
Ashwagandha is known as an adaptogen herb, which means that it can support your body with overall stress, both physical and emotional. This powerful herb has been shown to support healthy blood sugar levels, decrease cortisol, and boost brain function. Ashwagandha has been used for generations to help fight depression and anxiety, providing an overall sense of wellness. Native to North Africa and India, the Ashwagandha plant is a tiny shrub adorned with yellow flowers. It is popular in Ayurvedic medicine due to its numerous health benefits. Ashwagandha is a powerful anti-inflammatory that has also been shown to inhibit the growth of tumors. Key Takeaways:
"The ashwagandha plant is a small shrub with yellow flowers that's native to India and North Africa. Extracts or powder from the plant's root or leaves are used to treat a variety of conditions." Read more: https://www.ecowatch.com/ashwagandha-2630934552.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6160) Eat more artichokes! Their leaves contain powerful compounds thatprotect you from diabetes
Date:
April 04, 2019 09:27 AM
Diabetes has the harmful potential of damaging the liver, kidneys, and pancreas. Fortunately, research is now showing that the consumption of artichoke leaves can protect your organs from this oncoming threat. This was concluded after a study was performed on rats, giving them a certain amount of alloxan each day which mimicked the effects of artichoke leaves. Once tissue was extracted from their organs, it showed that it was much less damaged than those who were not exposed to the alloxan. Key Takeaways:
"People who are at risk of diabetes and other metabolic disorders would do well to add artichokes (Cynara scolymus) in their diet to lower their chances of getting the disease, according to researchers from the University of Sfax in Tunisia." Read more: https://www.naturalnews.com/2019-02-04-artichoke-leaves-protect-you-from-diabetes.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6119) Eating ginger regularly may suppress the negative effects of ahigh-fat diet
Date:
March 27, 2019 03:21 PM
A study, conducted by Korean researchers and published in the journal "Nutrients", found that consuming ginger extract can prevent some of the detrimental effects of a high-fat diet. In the study, 27 rats were divided into three groups. Members of each group were fed a high-fat diet. Members of two of the groups were also given ginger extract. One group was given a hot-water extract; the other group was given ginger extracted by high hydrostatic pressure. Both groups that received ginger extract had lower body weight and lower body fat percentage than the group that was given no ginger extract. Key Takeaways:
"Consuming ginger or taking ginger extracts regularly may help prevent some of the negative effects of a high-fat diet, according to a study published in the journal Nutrients." Read more: https://www.naturalnews.com/2019-01-26-eating-ginger-suppresses-the-negative-effects-of-high-fat-diet.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6100) Easily boost your immune system by eating more pomegranates, studyconcludes
Date:
March 27, 2019 10:34 AM
Pomegranates have long been recognized for their beautiful red seeds that present in a much more vibrant light than many other fruits. Now researchers are finding that pomegranates have several health benefits, especially when it comes to treating chronic inflammatory conditions. A study performed on mice showed that the inflammation biomarkers present within their systems were dramatically reduced when they were given pomegranate extract on a continual basis, showing that it could have a similar impact on humans. Key Takeaways:
"Scientists from King Saud University concluded that pomegranates can boost the immune system and treat diseases such as malaria." Read more: https://www.naturalnews.com/2019-01-27-easily-boost-your-immune-system-with-pomegranates.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6097) Botanical study concludes the antioxidant potential of small nettle
Date:
March 22, 2019 03:54 PM
Researchers from the University of Sfax conducted a study on small nettle to determine it’s antioxidant potential. The small nettle plant can improve nutrition, livelihood, and overall health. It is also rich in flavonoids, fatty acids, and vitamins. Small nettle has already been in use for medicinal purposes as it can serve as a natural remedy for allergies, asthma, and bacterial infections. To conduct the study the researchers used extracts from small nettle leaves and watched for antimicrobial activity. They observed antioxidant activity along with high concentrations of flavonoids and shows that the plants are very important for health applications. Key Takeaways:
"A study conducted by researchers from the University of Sfax in Tunisia was the first to show not just the antioxidant potential of small nettle (Urtica urens) but its antimicrobial activity as well." Read more: https://www.naturalnews.com/2019-01-19-botanical-study-concludes-the-antioxidant-potential-of-small-nettle.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6090) Herbal supplement gingko biloba found to prevent cell death in thebrain, improve recovery from stroke
Date:
March 19, 2019 02:48 PM
Dr. Yun Xu is the head of the neurological department at Nanjing University, and he has made a breakthrough in the data supporting the herb ginkgo biloba and its neurological advantages to those who have suffered from ischemic strokes. By pairing ginkgo biloba with regular doses of Aspirin, Dr. Xu was able to measure the levels of cognitive ability among a large group of patients dealing with post-stroke difficulties. The results showed that those who had ginkgo biloba administered with their dose had improved memory function, attention, language, and more. Key Takeaways:
"Ginkgo biloba is one of the oldest living species of a tree native to China. It is known to have been used in traditional medicine and as a source of food. The leaves and the nuts of the tree have a high nutrient content, and is best known for its positive effects on the brain and nervous system." Read more: https://www.naturalnews.com/2019-01-03-herbal-supplement-gingko-biloba-found-to-prevent-cell-death-in-the-brain.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6082) Why diabetics should drink more tea and eat more cherries
Date:
February 16, 2019 08:57 AM
If you are a diabetic, you should consider drinking more tea and eating more cherries. A recent study done by Brazilian researchers says that both of these can improve diabetes. Tea is a natural antidiabetic treatment used for some time because it boosts the immune system, improves blood flow, and even reduces the risk of cancer. they tested two groups, giving one natural extracts and the other treatments similar to acarbose or miglitol. Phenolic compounds, chlorophyll, and carotenoids appeared to be higher in participants that received the natural extracts. Key Takeaways:
"This study, published in the journal Pharmacognosy Research, was based on in vitro assays that determined the ability of combined extracts from the two to act as an antioxidant and to inhibit alpha-glucosidase activity." Read more: https://www.naturalnews.com/2018-12-13-why-diabetics-should-drink-more-tea-and-eat-more-cherries.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6035) Noni is great for your colon
Date:
February 08, 2019 08:23 AM
Gut flora is vital to digestive health. An imbalance in this causes many ailments, such as irritable bowel syndrome, poor nutritional uptake, and bloating. Fermented Noni has been shown to promoted growth of several good bacteria in the gut that relieves inflammation of the digestive tract. Noni has also proven effective in helping to relieve inflammation and pain in other parts of the body. Traditionally it has been used to help treat infections and has a positive aspect in lowering cholesterol and may help to prevent damage from stroke events. Key Takeaways:
"You can keep your digestive system healthy with the help of fermented noni (Morinda citrifolia L.)" Read more: https://www.naturalnews.com/2018-12-21-noni-is-great-for-your-colon.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6008) Scientists discover the potential use of papaya leaf juice fortreating dengue
Date:
February 06, 2019 02:38 PM
Dengue is an infection of the immune system that lowers platelet counts in the blood, causing a variety of issues, including clotting disorders and anemia due to the viral born illness. Papaya leaf juice has immune boosting properties, one of which is it encourages platelet production. It is also used to help treat jaundice and other liver related diseases due to its detoxification value. Papaya leaf juice can also aid in digestion, lower cholesterol, lower and help maintain blood insulin levels, and finally , due to its high vitamin A and C levels, improve skin appearance and health. Key Takeaways:
"A recent study by researchers from Jamia Hamdard University in India revealed that extracts from papaya leaves have potential use as a natural remedy for dengue since they exhibit immunomodulatory activity and promote the production of thrombocytes, also called platelets." Read more: https://www.naturalnews.com/2018-12-21-papaya-leaf-juice-for-dengue.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6004) 6 Reasons why boswellia is one of the most powerful herbal extracts available today
Date:
January 19, 2019 10:09 AM
The more common name for boswellia is frankincense, and it is known for having a plethora of health benefits. Frankincense is made from the gum resin that originates from the boswellia tree. This boswellia resin has the ability to promote several incredible health benefits such as helping fight against various cancers, as well as preventing them in the first place. This is due to the anti-inflammatory aspects of frankincense, and an acid called Acetyl-11-keto-?-boswellic acid that naturally has the ability to fight cancer. Key Takeaways:
"This herbal extract has a long history of being used as perfume, incense, and medicine due to is therapeutic and anti-inflammatory properties." Read more: https://www.naturalnews.com/2019-01-15-6-reasons-why-boswellia-is-one-of-the-most-powerful-herbal-extracts-out-there.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5976) The Arjun tree holds potential for lowering blood sugar andcholesterol levels
Date:
January 08, 2019 09:58 AM
According to the Journal of Ayurveda and Integrative Medicine, Arjun Tree extract may have benefits for moderating your blood sugar and also your cholesterol levels. Diabetics are at dramatically higher risk of dying from heart conditions, perhaps because hyperglycemia tends to raise blood pressure and damage the circulatory system. The study in question focused on Wistar rats that received a high-fat diet, and found that Arjun Tree extract improved insulin sensitivity and liver triglycerides, and exhibited a pronounced anti inflammatory effect. Key Takeaways:
"In this study, which was published in the Journal of Ayurveda and Integrative Medicine, the researchers were able to determine that Arjun tree extracts exhibit anti-hyperglycemic and anti-hyperlipidemic activity." Read more: https://www.naturalnews.com/2018-12-24-arjun-tree-lowers-blood-sugar-and-cholesterol-levels.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5942) Herbal additives such as cumin oil found to increase shelf life offresh fish fillets
Date:
November 26, 2018 02:52 PM
Fish is a popular edible. In fact the Food and Agricultural Organization estimates that fish eaters consume up to 163 million tons of the aquatic protein every year. That's a lot of fish to freeze. And, unfortunately, more so than is the case with other popular proteins, fish spoils easily, even when kept on ice. Adding a natural antimicrobial agent, such as the common kitchen spice, black cumin, could be an inexpensive and economy-boosting way to extend the shelf life of vulnerable fish. This premise has actually been tested and proven by researchers at the Firat University in Turkey, where a study that utilized black cumin oil to extend the life of fish fillets proved entirely successful. The study showed that no negative side effects endured from the process. In addition to improving the safety of fish, the researchers noted that the process was environmentally sound as well, as it required less energy. Key Takeaways:
"The use of natural antimicrobials such as organic acids, essential oils, plant extracts, and bacteriocins could be good alternatives to ensure food safety." Read more: https://www.naturalnews.com/2018-11-06-cumin-oil-increases-shelf-life-of-fresh-fish-fillets.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5859) Milk thistle shows promise in treating liver cancer
Date:
October 10, 2018 03:26 PM
When it comes to treating liver cancer, milk thistle my be the key. For yes this prickly, purple plant has been used for good liver function and is sought out for its anti inflammatory and antimicrobial qualities. This plant extracts silibinin which has anti-cancer effects on cancer cells. It also inhibits the cancer cells cycle and increases the death of cancer cells. This plant also has another compound called silymarin which is supposed to be more enriching than Vitamin E. Key Takeaways:
"New studies have shown that the protective benefits of milk thistle are far greater than conventional scientists could have ever imagined." Read more: https://www.naturalnews.com/2018-09-16-milk-thistle-shows-promise-in-treating-liver-cancer.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5781) This humble medicinal herb found in open grasslands found topromote wound healing in diabetics
Date:
September 29, 2018 09:52 AM
There are a bunch of different methods that pop up for healing purposes all over the world. Depending on where you are from, and who you know, you have definitely heard of a bunch. The fact of the matter is that not all healing patterns work for everyone. Everyone's body is different and it is not indicative of anyone if they are not taken well to a certain healing technique. Find what works for you to heal. Key Takeaways:
"The asthma plant is known to Indian tribespeople as barokhervi. It is widely used as a medicinal herb. The entire plant is used to treat wounds. Extracts are also used to amend all kinds of illnesses such as the plant’s namesake disease, asthma, as well as bronchial infections and coughing." Read more: https://www.naturalnews.com/2018-09-11-this-humble-medicinal-herb-found-in-open-grasslands-found-to-promote-wound-healing-in-diabetics.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5777) Why the Indian olive is one of the best superfoods of all
Date:
September 02, 2018 05:53 PM
In today's day and age, many people are going through a phase of where they want to eat very healthy and are willing to go to a very far extent to ensure that they stick to a diet. Now, there are things like Indian olive which is considered to be a super food. Of course there is acai and most people know what that is. However, Indian olive is a new one that has been received well by many. Key Takeaways:
"For the study, the researchers looked at the phenolic contents, antimicrobial, and antioxidant activities of the olive plant. They used three crude extracts of the leaf and bark extracts of the olive tree: chloroform, ethanol, and methanol extracts." Read more: https://www.naturalnews.com/2018-08-30-why-the-indian-olive-is-one-of-the-best-superfoods.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5740) Three nutrient dense superfoods that are easy on your digestion
Date:
June 23, 2018 05:54 PM
Eating wholesome, unprocessed, nutritious “superfoods” can help promote better health and compensate for some of the other obstacles we encounter in trying to improve our diets. Moringa, for example, provides dense leaves rich in 90 vitamins, 18 amino acids and a variety of antioxidants, and is usually prepared as a fine powder that can be added to beverages. Aloe Vera is also rich in a wide variety of nutrients, including some rare ones, and freeze dried extracts of Aloe Vera can provide an excellent source of this remarkable superfood. Perhaps most promising of all is chlorella, an algae and one of the most nutritious foods in the world. The cracked cell wall and fermented variants of this rich protein source are especially easy to digest. Key Takeaways:
"From toxic onslaughts to poor food choices, the amount of trip wires on the road to good health can be nauseating and can paralyze people into doing nothing at all." Read more: https://www.naturalnews.com/2018-06-21-three-nutrient-dense-superfoods-that-are-easy-on-your-digestion.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5644) Cannabis extract fights â??incurable formâ?? of Leukemia
Date:
June 20, 2018 04:44 PM
More and more researching is emerging surrounding the benefits of cannabis when it comes to its medicinal properties. A study was shown that involved a 14-year-old girl who was diagnosed with cancer. She had undergone several aggressive treatments such as chemotherapy, and her family wanted to seek out another alternative route. They started seeing a doctor who overlooked her consumption of cannabis for medicinal purposes, and it was shown to have quite a positive impact on her recovery. She ended up passing of causes unrelated to the cannabis use, but it doesn't take away from the success that medicinal marijuana helped her and her family achieve. Key Takeaways:
"There are plenty of anecdotal reports of the successful use of cannabis in treating cancer, but few cases occur under conventional medical supervision, and virtually none make it into a peer-reviewed biomedical journal as a case report." Read more: https://www.healthnutnews.com/cannabis-extract-fights-incurable-form-of-leukemia/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5636) Not just for coffee: Cinnamon found to have potent anti-cancer effects in latest research
Date:
June 13, 2018 09:16 AM
Two South Korean colleges performed a study in which they hypothesized that cinnamon could successfully decrease the growth rate or infiltration status of certain cancer cells. They found that Chinese cinnamon was able to successfully decrease the amount in which cancer cells were able to infiltrate healthy cells when it comes to colorectal cancer specifically. However, the findings showed that this is not the only area in which cinnamon derived from the Chinese twig can help aid in cancer prevention and recovery. Key Takeaways:
"Based on the findings, researchers discovered that extracts derived from the twigs of the Chinese cinnamon were able to reduce the chances of human colorectal cancer cells to infiltrate other cells successfully." Read more: https://www.naturalnews.com/2018-06-10-not-just-for-coffee-cinnamon-potent-anti-cancer-effects-research.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5633) 5 Trending Adaptogenic Herbs To Reduce Anxiety And Depression
Date:
May 30, 2018 09:16 AM
Adoptogenic herbs are herbs that help the body to achieve balance. There non-specific nature is actually their strength, as the herb works to alleviate stress, by boosting what's lacking and reining in what's excessive, from nose to toes, across the body. And since it's all about stress, the herb makes no distinction between physical or emotional stresses. Studies have shown that various psychological conditions, such as anxiety, chronic stress, acute stress and depression are impacted in a positive way by adoptogenic herbs, such as Astragalus, Holy basil, and Asian Ginger. Key Takeaways:
"Everyone in the health world wants a piece of the adaptogenic action, and it’s not without reason." Read more: https://www.thealternativedaily.com/5-trending-adaptogenic-herbs-to-reduce-anxiety-and-depression/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5617) Were we wrong about fiber?
Date:
May 28, 2018 09:16 AM
In Uganda they primarily eat a plant-based diet. By adhering to this diet, it took 26 years before experts could find a case of a patient with coronary heart disease. Many researchers say that this is due to their diet containing so much fiber. However, it is important to note that fiber cannot come from extracts and supplements and provide us with the same beneficial results. In order to get the full impact, it needs to come from your diet. Key Takeaways:
"Heart patients who increase their intake of fiber after their first heart attack reduce their risk of a second and live longer than those who don’t." Read more: https://www.healthnutnews.com/were-we-wrong-about-fiber/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5612) Hibiscus extracts can be used to provide natural food coloring WITH health benefits
Date:
March 28, 2018 09:17 AM
While the hibiscus is known as a very ornamental bloom, gracing many gardens, it has an economic role to play as well, serving as a product of high significance in both the food and cosmetic industries. This dual nature of the plant arises from the fact that the hibiscus is both highly nutritious and also the source of a safe coloring agent that can be used even in foods. The periodical, 'Food Science and Human WellnessWellness', explored the viability of hibiscus-generated food coloring for cupcakes and found the resulting product to be both cost-effective and 'clean, ' with the added benefit of adding necessary flavonoids into the human diet. These anthocyanins, aside from the nourishment they provide, appear to be linked with the easing of numerous health complaints, including, hypertension, inflammatory conditions, coughing and excess weight. Key Takeaways:
"Extracts from hibiscus calyces could be used as a natural food coloring, which can provide health benefits at the same time, according to a study published in the journal Food Science and Human Wellness." Read more: https://www.naturalnews.com/2018-03-26-hibiscus-extracts-can-be-used-to-provide-natural-food-coloring-with-health-benefits.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5565) Reds Pak has over 150 Nutrients Per Packet
Date:
March 21, 2018 01:39 PM
Contains:
If you are looking for a great reds supplement, give Trace Minerals Research a try, This Reds Pak is Gluten free and Certified Vegan. Reds Pak is a full-spectrum antioxidant supplement of energy-packed whole foods and extracts, super fruits, vegetables, and other essential nutrients for superior health. It is designed to help maintain cellular integrity, support cardiovascular health and immune system function, provide increased energy, support healthy digestion, and fight against free radical damage.** Red Pak also Contains a Proprietary Liver Supplement Blend and an Enzyme & Probiotic blend that work together to support healthy digestion and aid in the processing and elimination of harmful toxins.** The digestive enzymes help break down macronutrients and absorption while the probiotics help boost production of the beneficial cultures that naturally reside in the digestive tract for good gut flora and healthy bacterial balance of the intestines.** To complete the formula, a complex of over 72 ionic trace minerals are added. Feel the difference, give it a try!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5559) Anise Seed Benefits Blood Sugar & May Protect Against Ulcers
Date:
January 23, 2018 03:59 PM
Anise seeds are now being seen as one of the latest in a line of good for you herbs and spices. They are in the same family as celery and carrots, but with a slight licorice flavor. They have been found to have many properties to aid with health including lowering blood sugar and treating depression. The properties of anise itself, often seen as a digestive, can aid with stomach ulcers and maybe even stop the growth of fungus and bacteria. Key Takeaways:
"More recently, researchers have uncovered a host of health benefits associated with anise seed, including improved blood sugar levels, decreased menopause symptoms and even protection against stomach ulcers." Read more: https://draxe.com/anise-seed/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5502) Scientists call on feds to allow research on CBD for pets
Date:
December 10, 2017 03:59 PM
Veterinarians, researchers and pet owners are looking to loosen federal regulations on the use of marijuana products to help treat sick animals. Medical issues in dogs, such as epilepsy, arthritis, anxiety, loss of appetite and inflammation could potentially by helped by marijuana-based drugs and extracts. Some people are already using marijuana extracts on their animals, such as those containing CBD, which is an element of marijuana that is not psychoactive. However, such extracts continue to be listed as Schedule 1 drugs by the Federal Drug Enforcement Administration, even when they contain little or no THC. THC is the active component in marijuana that causes intoxication. The Food and Drug Administration has warned that marijuana products for pets sold in animal hospitals or online pet stores are illegal, since such drugs are unapproved. The FDA has suggested it will pursue legal action against those in violation of the law. However, the policy-making body of the American Veterinary Medical Association, in conjunction with two group councils, is considering making a recommendation to the DEA for marijuana to be declassified as a Schedule 1 drug in order to enable research for both animal and human medical purposes. Declassification could also help prevent pet owners from accidentally overmedicating their animals in the absence of proper guidance from a medical professional. In September, Republican senator Orrin Hatch of Utah introduced a bill that would facilitate research on use of marijuana-based medications, concurring that the drug is over-regulated, although he continues to oppose recreational use of the drug,. Some veterinarians note that without sufficient evidence, it remains unsafe to use marijuana products on animals, with concerns about potential toxicity. Yet researchers are continuing to wait for clearance to proceed on various relevant studies, such as use of marijuana for dogs with osteoarthritis, pruritis and epilepsy. Some research on use of products with CBD has been stopped until federal approval is granted. Gaining approval has been difficult due to government requirements, which continue to be an obstacle to moving forward. Key Takeaways:
"The concern our membership has is worry about people extrapolating their own dosages, looking to medicate their pets outside the realm of the medical professional" Read more: https://www.aspentimes.com/news/scientists-call-on-feds-to-allow-research-on-cbd-for-pets/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5432) Turmeric may reduce inflammation from osteoarthritis
Date:
November 01, 2017 12:59 PM
Osteoarthritis is a condition affecting many people and without a cure, the condition turns lives upside down. Fortunately for sufferers, osteoarthritis inflammation and pain can be reduced with many at-home, natural remedies you probably already have lying around. Turmeric happens to be one of the remedies that works wonders for anyone who uses it and is suffering from this painful condition. Immediate inflammation relief is just one of the many benefits you enjoy when using turmeric for inflammation reduction. Key Takeaways:
"A recent study published in the Journal of Medicinal Food demonstrated that extracts of turmeric have a significant impact on the inflammation and pain associated with osteoarthritis." Read more: http://www.dailyherald.com/entlife/20171028/turmeric-may-reduce-inflammation-from-osteoarthritis
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5386) Men can boost brain health and enhance performance with ginkgo
Date:
October 08, 2017 10:14 AM
Men can greatly boost their brain health and enhance their performance with ginkgo. Young and active men can greatly benefit from taking extracts from Ginkgo biloba leaves. This is according to a recent study. The great thing about Ginkgo is that it can also combat memory issues that are related to dementia. They help boost the brain functioning in people that are having issues with dementia. Rats were used in studies and some interesting things were discovered. Key Takeaways:
"According to the researchers, the plant extracts’ positive effects may be stemming from its polyphenolic compounds." Read more: https://www.naturalnews.com/2017-10-02-men-can-boost-brain-health-and-enhance-performance-with-ginkgo.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5319) Ginseng extracts found to prevent obesity
Date:
September 25, 2017 12:14 PM
Obesity is a huge problem. More and more people suffer from it. It can lead to heart and other problems. There are things you can do such as eating right and exercising. Ginseng extract is also helpful. This extract has other health benefits as well so would be a great addition to anyone's health routine. Ginseng can also be found in some kinds of soda and other healthier drinks. There are many ways to take it in. Key Takeaways:
"both groups noted significantly lower levels of abdominal and epididymal adipose tissue mass" Read more: http://www.naturalnews.com/2017-09-15-ginseng-extracts-found-to-prevent-obesity.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5279) What is Okra Good For? 5 Wonderful Benefits of Okra
Date:
September 21, 2017 09:14 AM
Okra is a versatile plant that can provide both nutritional as well as health benefits. In terms of cooking, Okra can be prepared to your preference through roasting, boiling, frying or stewing. It can also be steamed to extract a gooey substance that can then be further utilized as a thickener in other recipes. But Okra also has numerous health benefits as well. It is effective at filtering your blood, aiding in the treatment of kidney deisease. It acts as an antioxidant and is particularly useful in protecting you from liver diseases. It also helps regulate blood sugar levels leading to the belief that it is a viable alternative treatment for those affected by diabetes. It also has been shown to be an effective alternative for treating depression. But perhaps the most exciting application is the possibility it presents in the treatment of breast cancer. This is currently being studied, but so far it seems that extracts gathered from Okra have shown promise in reducing the growth rate of cancer cells, and in eradicating some existing cancer cells. So this is an exciting development that bears further investigation. Given the vast list of proven and potential benefits previously listed, Okra seems to be a vegetable that we should all be giving serious consideration to adding to our diets. Key Takeaways:
"Okra extracts were used in a study performed to treat human breast cancer cells due to its high lectin content. The treatment both reduced cancer cell growth by 63 percent and killed 72 percent of the cancer cells." Read more: https://www.youtube.com/watch?v=PgEOZOi-2Uo
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5267) Organic onions richer in flavonoids
Date:
July 08, 2017 12:14 PM
Many studies have tried and failed to successfully prove whether organically grown foods are truly healthier then conventionally grown produce. A six year long study showed that onions grown organically consistently have ten to fifty percent more flavonoids then the conventionally grown onions, however, the difference in the amounts of flavoniods could have been caused by diffences in soil type, pest control or many other variables. Although higher in flavonoids, the studies still are inconclusive whether the higher amount makes the organically grown produce healthier then conventionally grown onions. Key Takeaways:
"Consistently higher levels of individual flavonoids were also present in the organic onions, and the extracts had higher antioxidant activity in two assays that measure radical scavenging activity." Read more: http://cen.acs.org/articles/95/web/2017/06/Organic-onions-richer-flavonoids.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4943) Cannabinoids can successfully kill leukemia cells, reveals groundbreaking new study
Date:
June 21, 2017 12:14 PM
Leukemia, which is prevalent in both children and adults, is a bone marrow cancer that results in an abnormal production of white blood cells.As for leukemia treatment, now it’s simply a matter of figuring out the most optimal combinations for greater effectiveness. Cannabis has long been known as having the ability to kill cancer, but the new revelation regarding leukemia is important because the disease is a cancer of bone marrow and other blood forming organs. Key Takeaways:
"The study revealed that the cannabiniod varieties cannabidiol and tetrahydrocannabinol (THC) eliminated leukemia cells when used alone." Read more: http://www.naturalnews.com/2017-06-20-cannabinoids-can-successfully-kill-leukemia-cells-reveals-groundbreaking-new-study.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4862) Lemongrass: The Herbal Remedy That Works Wonders
Date:
May 27, 2017 07:14 AM
Lemongrass is an herb known for its role in many citrus and herbal teas. Originating in Africa, it has a long history in Indian culture, Thai cuisine, and, more recently, Western markets. In addition to this, though, it offers many useful health benefits. Its oil has been used in treating anxiety, its extracts in fighting bacteria and fungus, and its tea in treating fevers. Although most known for its products as a tea, lemongrass oil has become more and more common in recent years. Read more: Lemongrass: The Herbal Remedy That Works Wonders
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4704) Is pine tree bark the key to healthier, stronger teeth?
Date:
April 13, 2017 03:44 PM
Not many people would associate pine tree bark with stronger teeth, but it's proving to be useful in strengthening the teeth and making fillings bind more effectively. This is because the compounds in pine tree bark are shown to strengthen the layer of teeth underneath the enamel. Tests performed by Dr. Guido Pauli are showing that this extract can strengthen dentine (the teeth material under the enamel) by up to ten times. Read this article for more details. Key Takeaways:
"Dr. Guido Pauli of the University of Illinois at Chicago says the “weak link in the chain of bonding is the interface between the resin and the dentine." Read more: http://www.naturalnews.com/2017-04-08-is-pine-tree-bark-the-key-to-healthier-stronger-teeth.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4403) Oakland Cannabis Company Gives Back to Cancer Patients
Date:
March 21, 2017 06:44 PM
Jetty Extracts, a cannabis company based out of Oakland, has been helping cancer patients for years with the Shelter Project which gives patients access to cannabis oil. The project started out with its founder, Matt Lee, and others involved simply giving this oil to friends and family members in need. It has since grown to benefit about 400 patients who receive a monthly care package. In this article, Lee talks about how he got the idea for the Shelter Project and how the project has grown since it began in 2013. Read more: Oakland Cannabis Company Gives Back to Cancer Patients
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4253) DEA Reiterates: Hemp CBD is Illegal
Date:
March 19, 2017 03:44 PM
The DEA has reiterated that Hemp CBD is illegal. It does not matter what the sellers of CBD oil tell you, it is illegal. The DEA believes it is illegal in all fifty states. The authority that the DEA has over drugs comes from the Controlled Substances Act. This issue is important to many people. Key Takeaways:
"The term ”marihuana” means all parts of the plant Cannabis sativa L., whether growing or not." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4225) Here Is Why Congress Believes Marijuana Is The Same As Heroin And Meth
Date:
March 12, 2017 11:59 AM
Congressman Garrett is working to get marijuana off the federal controlled substance list, which will put marijuana on a level similar to alcohol rather than heroin. The Controlled Substance Act, passed in 1970 by President Nixon, lists marijuana as a tier 1 substance (the highest possible tier, meaning no acceptable medical use), while only 2 years after it was discovered that marijuana posed no threat to the public. While marijuana is considered highly dangerous to the federal government, twenty-eight state governments so far have passes laws allowing medical marijuana. Even cannabis extracts with no THC are considered schedule 1 drugs. And yet, congress has no plan to reschedule any time soon, with several recent attempts all proving unsuccessful. Key Takeaways:
"Earlier this week, Congressman Tom Garrett, a Republican freshman from Virginia, introduced legislation aimed at federally decriminalizing marijuana." Read more: https://www.google.com/url?rct=j&sa=t&url=https%3A%2F%2Fthefreshtoast.com%2Fcannabis%2Fhere-is-why-congress-believes-marijuana-is-the-same-as-heroin-and-meth%2F&ct=ga&cd=CAIyGjViYjkzZDJlODZhNjI0ZWE6Y29tOmVuOlVT&usg=AFQjCNGVMruuanmcWtstgLlU4juLWyStng
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4118) Possible new head of the FDA is a supporter of medical marijuana … Could Trump's FDA finally stop suppressing cannabis?
Date:
February 04, 2017 12:59 PM
Back on November 8th 2016 there was much celebration among the marijuana community. There were four more states that legalized adult use cannabis and several, including Florida, that legalized medical marijuana. However, there was still a lump in the back of many of our throats. Sessions has a long standing anti-drug stance and has made some strong comments against cannabis legalization. Recently the Trump administration has made a surprising announcement when they confirmed previous reports that Jim O'Neil is being considered to lead the Food and Drug Administration. Key Takeaways:
"For decades, cannabis advocates have pushed for universal legalization of medical marijuana. Citing scientific study after scientific study, they have forcefully (and truthfully) argued that legalization would provide much needed relief to millions of people suffering from a host of medical ailments." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3882) How rooibos can protect you against the sun
Date:
January 06, 2017 12:59 PM
Rooibos tea is a versatile drink. Researchers have determined it can undo some of the damage caused by harmful rays of the sun. Scientists have been studying how rooibos protects against inflammation of skin cells for the past eleven years. Rooibos extracts are able to remove precancerous damaged cells and block the beginning of inflammation after the skin has been exposed to the sun’s ultra-violet rays. There are more tests that must be done before an after sun exposure product will be available for purchase. Key Takeaways:
"About 80 per cent of sun-induced skin damage occurs before the age of 18, therefore it is imperative to take special care of children in the sun." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3750) The Sky's Not Falling! Media Misreporting DEA on CBD “Illegality”
Date:
December 23, 2016 12:59 PM
The Drug Enforcement Agency (DEA) recently created a new code for tracking of cannabis extracts, independent of the code that tracks cannabis itself. This minor tweak to their paperwork unfortunately set off an internet scare, with multiple news sources stating that the new code effectively reversed cannabis and hemp legality when dealing with extracts rather than plants. That was not the case: the DEA has made clear that their coding system has no legal implications, and those statements have been confirmed by industry and legal experts. Key Takeaways:
"Later, in a follow-up phone interview Baer reiterated to The Cannabist that the move allows the DEA to more accurately track elements such as scientific and medical studies, as researchers use the codes to identify which substance they’re examining." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3691) The empire strikes back: DEA quietly announces "Schedule I" status for CBD extracts to comply with United Nations demands... CBD Prohibition begins on January 13, 2017
Date:
December 23, 2016 10:59 AM
There is concern over a rumor that the DEA seeks to create a brand new schedule I class of drugs just for marijuana extracts, known as CBD. They must go through a scheduling action to get approval, but many are outraged over the possibility of losing access to any medicinal product made from Cannabis. This can include non-psychoactive drugs. Some are trying to soothe the panic by stating that it doesn’t include hemp products. As long as it is not a drug, it is not restricted. We will have to wait and see how this plays out. Key Takeaways:
"Big Media, Big Pharma, Big Government, Big Banks and Big Agriculture are assaulting our bodies and minds by the hour, it seems." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3690) Do You Know The Benefits Of Olive Leaf Extract?
Date:
December 20, 2016 06:08 PM
Olive leaf extract offers several health benefits that you cannot get from other types of extracts. It has a wide range of unique health properties that work against symptoms and diseases. Here are some of the major benefits.
Prevention and inhibition of cancer
One of the major benefits of olive leaf extract is that it has the ability to offer protection against breast cancer. The good thing is that it helps prevention of the escalation of the problem at an early stage in its growth cycle.
Boost development of bones
Olive oil extract helps in stimulation of the production of bone building cells also referred as osteoblasts. This helps in prevention of the loss of bone density and helps in fighting osteoporosis.
Antibacterial and antiviral properties
The compounds found in olive leaf extract contain a unique feature that makes it have the ability to fight against different microorganisms such as viruses and bacteria. The compounds impair viruses, thus making them lack the ability to develop amino acids. This makes it impossible for them to reproduce and multiply. These compounds act against microorganisms in a way that antibiotics cannot.
Antioxidant effect
Olive leaf extract has several phenols, which are antioxidants that help in neutralizing the action of free radicals. Free radicals refer to active substances that destroy the process of DNA creation.
Anti inflammatory properties
Another common use of the olive oil extract is that it helps in treatment of various infections in the body. Oleuropein which is one of its major compound has anti microbial activity that helps reduce and boost inflammation. This means that it helps in reducing inflammation in the body.
Lower blood pressure
Studies have showed that oleuropein has the ability to relax your blood vessels, reduce blood pressure and helps in prevention of blood clot formation. It also helps stop irregular heartbeat, balance blood sugar levels and improve flow of blood in the coronary arteries.
References
https://draxe.com/olive-leaf-benefits/
www.about-olive-leaf-extract.com/benefits-of-olive-leaf-extract.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3679) Food with avocado extract could prevent bacterial illness
Date:
December 09, 2016 10:59 AM
A recent study has found that extracts from avocado seeds can potentially be used as a natural additive incorporated into ready-to-eat foods to control microbes that cause Listeria. Listeria is a foodborne bacterial illness that can be very serious for pregnant women and people with impaired immune systems. Researchers from Tecnologico de Monterrey in Mexico compared enriched acetogenin extract from avocado seeds with two name-brand synthetic antimicrobials. While humans already consume acetogenins from avocado pulp that are above antilisterial levels, bioavailability and safety of the extracts from avocado seeds need further assessment. Key Takeaways:
"A recent study has found that extracts from avocado seeds can potentially be used as a natural additive incorporated into ready-to-eat foods to control microbes that cause Listeria." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3605) Oregano Plant Is the Most Potent Antimicrobial In The world
Date:
November 15, 2016 07:24 PM
Along with its culinary usage, oregano shows antimicrobial and antioxidant properties and possess probable activity like an antispasmodic and in diabetes. But there is no clinical proof to facilitate the usage of oregano in any signs. Normal or wild oregano is a perennial plant grown in the Mediterranean region and Asia. It is also cultivated in the United States. The creeping rootstock of oregano makes a downy, square, purplish stem with reverse ovate leaves. The plant stem also grows about 76cm tall. Purple two lipped flowers develop in terminal groups from July to October. Features of OreganoThis plant has been a normal ingredient in Italy, Spain and Italian dishes like a spice and flavouring compound for several years. Its basic purpose was like a cautious digestive and circulatory stimulant. This plant has been availed in perfumery for the volatile oil materials, particularly in scenting soaps. The antiseptic feature of medicinal and aromatic plants and the extracts have been identified since antiquity. It has been recommended that an infusion of the new herb is useful in treating a collapsed stomach and indigestion, colic, headache and nervous problems as well as for some respiratory ailments. A mixture of the flowers has been utilized to avoid seasickness. Uses of OreganoThe oil of this plant has been availed externally in lotions and liniments and to ease toothache. Oregano has been utilized like an ant repellent. Oregano has ursolic and oleanolic acids, hydroquinones, flavonoids, rosmarinic, caffeic,tannins, lithospermic acid and phenolic glycosides. The compounds of phenolic represent seventy one percent of the full oil. The carvacrol and polar phenols thymol are accountable for several of the properties of the necessary oil as well as terpinene and P-cymene. Research has compared the impacts of oregano necessary oil, carvacrol and thymol on fungi. All three totally reduced fungal development of aspergillus and penicillium species. The oil also seems to possess certain activity against Candida species, probably due to the reason of its carvacrol content. The oregano volatile oil have explained in vitro antibacterial activity against different types of gram negative and gram positive microorganisms like pseudomonas, listeria, salmonella, proteus and clostridium species as well as certain methicillin resistant. There are different reports explaining antiparasitic activity of oregano. The origanum vulgare oil has been presented to remove normal parasites in pheasants and chickens. There are also some other Potent Antimicrobial seen in the world like clove, cinnamon, nutmeg, onion, garlic, anise, sassafras, ginger. These all have certain amount of antimicrobial properties in it. Related Products
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3451) The Health Benefits of Grape Seed Extract
Date:
November 14, 2016 10:20 PM
Grape seed extract is most commonly a waste product produced by the grape juice and winery industry. This is because grape seed extract doesn't go into finished drinks. Grape seed contains a wide variety of health-enhancing ingredients like protein, carbohydrates and lipids (healthy fats). Immune systemA study done on healthy volunteers found that grape seed considerably increased the levels of antioxidants in the blood. So, another one of the benefits of grape seed is it helps boosts the immune system to fight against harmful compounds which may reduce the risk of chronic diseases including breast, stomach, colon, prostate and lung cancer.
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Memory Loss
Nicotinamide Adenine Dinucleotide (NADH) is an activated form of B vitamin niacinin, which is available naturally in the body, from poultry, meat, fish and in minimal quantities from vegetables and fruits. This substance is also commonly referred to as the most important coenzyme mainly because of the import role of transforming food-based energy into energy, which can be utilized by the body cells. Due to the roles played by NADH, it has been developed into supplements, which have various benefits. NADH role in the body is important since the body cannot utilize the energy inform of whole proteins, carbohydrates and fats which are the main sources of energy. 
Green tea is made from the leaves of Camellia Sinensis, which is recognized for its health benefits. The nonfermented product is obtained by leaf desiccation that contains potent, polyphenolic antioxidants, with a flavanolic structure referred to as green- tea catechins, including epigallocat-echin-gallate (EGCG). Studies have shown that drinking EGCG prevents carcinogenesis in rodent organs. Studies have shown it had a significant chemoprotective effect against DMBA-induced mammary tumorigenesis in rats. Human breast cancer cell proliferation inhibition by green tea appeared mediated in part by (CKI). Mutagenesis was inhibited at concentration levels equivalent to human daily consumption.
Guggul extract on weight loss
Echinacea tea is Associate in Nursing flavoring remedy that several realize to be quite effective in fighting off colds, cough and respiratory disease. Plenty of individuals take asterid dicot genus tea as they believe it helps stop and even stop these ailments. After all, the herb has long been called Associate in Nursing immunostimulant that helps strengthen the system and beat back infections.
Almonds are fruits of deciduous trees that are originally found in North Africa and Asia. There are two varieties of almonds, sweet and bitter. Sweet almonds can be used to produce essential oil, and extract. Almond extract is often used as an alternative to vanilla extracts in diabetic safe recipes. Bitter almonds contain a toxic amount of prussic acid that can be converted to cyanide during refining, consequently prussic acid has to be leached out, before it can be suitable for human consumption. 
What is Citrimax
