Search Term: " Gracefully "
five anti-aging food found in the grocery store
November 13, 2016 06:46 AM
The choices we make at meal time affect how we age. By choosing healthy options, some of the common symptoms of old age can be reversed, removed, or masked. Many vitamins and nutrients prevent diseases that are mostly diagnosed during old age and maintain a healthy body. Eating correctly is essential to preserving our youth.
"Tomatoes, eggplants, blueberries, blackberries, and other colorful fruits are packed with antioxidants. These help combat free radicals that damage healthy cells and suppress the immune system."
Resveratrol, Longevity, and Aging
August 04, 2009 01:34 PM
Today growing older means more than settling into a comfortable armchair with the TV remote. Healthy aging means staying active and vigorous long into old age - not aging Gracefully. An now intervention in the aging process - once regarded as fantasy - is within reach due to advances in nutritional science. One of the most exciting discoveries is resveratrol, a protective compound produced by grapes and other plants in response to environmental stress.
Stonger and more potent formulas are becoming available every day resveratrol included. One company Source Naturals has now produced a resveratrol product featuring 200 mg of pure resveratrol from traditional Chinese herb Hu Zhang (one of the richest sources) and from red wine extract.
A recent study at the Harvard Medical School reported that resveratrol triggers genes in mice that support longevity and metabolic balance. By stimulating SIRT I genes, it mimics the healthy aging benefits of caloric restriction. Resveratrol addresses the metabolic inflammation so prevalent in today’s society by inhibiting NF kappa-B and COX-2 enzymes. And it provides antioxidant protection to the cardiovascular and immune system. In fact, of the dozens of SystemiCare metabolic systems indentified by Source Naturals as necessary for optimal health, resveratrol positively affects five: cells/DNA; inflammation response; antioxidant defense; circulation; and immunity.
Have you given resveratrol a try? Staying healthy and living longer is appealing to all individuals who are climbing the age ladder.
February 04, 2009 09:17 AM
It has been announced that it pays to take your vitamins, as the American Medical Association has completely reversed its previous anti-vitamin stance after twenty years and is now encouraging all adults to supplement daily with a multiple vitamin. After this decision, a review of 38 years of scientific evidence has convinced the Journal of the American Medical Association (JAMA) to rewrite its policy guidelines regarding the use of vitamin supplements.
It is common knowledge that today's diet is not providing sufficient nutritional value to keep chronic diseases at bay. Although nutrient intakes in North American are generally sufficient to avoid overt vitamin deficiencies, sub-clinical deficiencies are extremely common. Most vitamins and minerals come mainly from fruits and vegetables, causing us to need at least five daily servings of each. Studies have found that the number of servings of fresh fruits and vegetables is well below the recommended fiver servings per day, with the intake of dietary iron, folic acid, and calcium being significantly below recommended levels for adolescent girls.
Not many people know that cardiovascular disease is a problem that has been cultivated by modern society, with the first report on cardiovascular disease in America being published in 1912. At that time, the disease was so rare that it took years to find. In less than 100 years, the changes to our lifestyle, environment, and to the food we eat have made cardiovascular disease the number one killer in North America.
A groundbreaking report on July 13, 2000 tied the development of most cancers to lifestyle and the exposure to environmental and occupational risk factors. Although a genetic influence was not negated, as it appears to account for about 30% of total cancer risk, the findings placed the blame on poor dietary habits, smoking, alcohol consumption, lack of exercise, and exposure to environmental toxins. It has been recommended that a diet made up of plant-based foods which include vegetables, fruits, and grains is essential.
Stroke, the third-leading cause of death in the most developed countries for decades, occurs when blood flow to the brain is cut off due to a thrombotic event in one of the major arteries feeding the brain. A major cause of disability among adults and a principal factor in late-life dementia, small strokes can often go unnoticed. Because hypertension is the major cause of stroke, potassium and its blood pressure-lowering abilities are often helpful. Additionally, nutrients such as folic acid, bioflavonoids, polyphenols, and assorted antioxidants play an important role. The consumption of citrus fruit juices that contain high levels of vitamin C, and cruciferous vegetables like broccoli, cabbage, Brussels sprouts, bok choy, and cauliflower give protection against stroke.
Not only are we not eating enough of the proper food groups, the foods we do eat are often short in vital nutrients and high in calories. Nothing can replace the value of a diet that is carefully balanced. However, in today's high-stress world, we often face a absence of physical activity and a surplus of meals on the run, consisting of fast-food and processed foods that lack nutritional value. We should never neglect the importance of a well-balanced diet that is high in fruits and vegetables and we should make every opportunity to eat as close to the earth as possible.
Unfortunately, in today's fast-food world, it is hard to get away from the high-calorie, low-nutrition, over-processed, corporate food culture. If you value your health, it makes sense to take the extra step and start supplementing your diet with nutritional supplementation, as it is your personal health insurance to help you age Gracefully. Stop into your local or internet health food store and look for a good multiple vitamin supplement to help boost your current diet.
Phytoestrogen - Plant Estrogen
September 25, 2008 05:57 PM
Phytoestrogens mainly belong to a group of phenolic compounds known as flavonoids: the coumestans, prenylated and isoflavones are three of the most active in estrogenic effects. Phytoestrogens are not considered as nutrients because the lack of in the diet will not produce any characteristic deficiency syndromes nor do they participate in any essential biological function. Phytoestrogens are considered archi-estrogens (naturally occurring) and as dietary phytochemicals they are considered as safe and effective in its estrogenic activity.
Phytoestrogen content varies in different foods, and may vary significantly within the same group of foods due to the way these foods are grown such as soil content. Phytoestrogen when consumed as a treatment for menopause was well tolerated and caused no changes in liver enzymes, creatinine levels, body mass index, or blood pressure. Phytoestrogen is found in a wide variety of edible plants and generally display both estrogenic and anti-estrogenic properties.
Canadian researchers examined the content of nine common phytoestrogens foods in a Western diet, foods with the highest relative phytoestrogen content were nuts and oilseeds, followed by soy products, cereals and breads, legumes, meat products, and processed foods that may contain soy, vegetables, fruits, alcoholic, and nonalcoholic beverages. Researchers are also studying if phytoestrogens can prevent prostate cancer, preliminary results are promising. Researchers focused primarily on the compound isoflavones because of its greater abundance in soy plus it exhibit estrogenic properties in the same strength as the other phytoestrogens compounds..
Isoflavones are structurally similar to the estrogen in human body’s, and thus have been shown to possess both estrogenic and anti-estrogenic activity. Isoflavones may directly inhibit bone re-sorption and prevent the onset of osteoporosis. The weak estrogenic effects of isoflavones have been postulated as being protective against various forms of cancer as well. Being that isoflavones are chemically similar to estrogen, one can take isoflavones as an estrogenic replacement with little to no side effects.
Two other clinical trials suggest that over the short term, soy isoflavones may reduce lumbar spine bone loss in peri- and postmenopausal women. Red Clover contains all four estrogenic isoflavones: biochanin formonoetin daidzein Genistein. Much research has been performed on soy and red clover based phytoestrogens sources. We do not eat much red clover and so we will focus more on soy sources.
Soybeans contain large amounts of isoflavones or phytoestrogens such as genistein, daidzein, glycitein, and isoflavones. Soybeans display a biological effect when ingested by humans and animals. Soybean oil is the most commonly used vegetable oil in the United States and Europe. Soybean oil contains approximately 61 percent polyunsaturated fatty acids making it a healthy alternative to other oils currently available on the market for cooking.
Soybeans contain high levels of phytoestrogens and are the most widely used oil in the United States, and is sold as either pure soybean oil or as a main ingredient in vegetable oil. Most of the supplements on the natural foods market contain isoflavones derived from soybeans or red clover and some contain botanicals such as black cohosh.
Phytoestrogen flavonoids and lignan exhibit significant antioxidant activity which is great for those anti-aging minded individuals. The antioxidant activity in flavonoid and lignan helps support breast, heart and bone health. Antioxidants can reduce free radical damage in the body as well as reduce oxidative stress which causes aging. We all know that over time we age, phytoestrogens might help one age more Gracefully.
Finally, phytoestrogens, sometimes called "natural estrogens", are a diverse group of naturally occurring non steroidal plant compounds that, because of their structural similarity with estradiol (estrogen), have the ability to cause estrogenic or/and anti-estrogenic effects in the body. Isoflavones are found in high concentration in soy bean and soy bean products changing ones diet to more soy based foods or taking a phytoestrogens supplement can help reduce estrogen related cancers and maybe even prostate cancer.
Growing Older, Feeling Better
March 28, 2007 02:15 PM
Growing Older, Feeling Better
Not long ago, when a man turned sixty-five, he became officially old – the best years of his life far behind him. The milestone meant his working days were done and if he was lucky, he might get four or five years to spend as he wished before illness and infirmity set in. It was simply expected and accepted that the older a man got, the sicker he got.
Well, not anymore. Today, a man age 65 is just as likely to be found hiking in the hills, running in a marathon, or even dancing in the streets than rocking in that proverbial front porch rocker. Because it’s becoming more and more evident that the older a man gets, the healthier that man has been.
Eating healthy, exercising, and kicking harmful habits (like smoking) can add years to a man’s life. Aging research is proving over and over again, that we can prevent and delay heart disease, cancer, diabetes, and Alzheimer’s disease – the major causes of disability and death in men over 50.
Now, it’s very true that good clean living from early on is preferable to sixty five years of bad habits and five years of good. But it’s also true that it’s never too late for men to make changes and vow to take better care of themselves. And one of the easiest and most effective ways men can improve their health is the addition of high quality nutritional supplements.
In this issue of Ask the Doctor, we’ll talk about specific dietary supplements that have been scientifically shown to improve the health of men over fifty, prevent the diseases that often strike at this crucial time in men’s lives, and actually slow the aging process.
Q. I just turned 50 and I’d like to begin taking nutritional supplements, but they seem so confusing. Where should I begin?
A. Many men feel the same way. There are literally hundreds and hundreds of nutritional supplements on health food store shelves. Figuring out which supplements provide the best health benefits for a 50+ man can be overwhelming.
The best foundation supplement is a high quality multivitamin. Research is repeatedly finding that even very healthy men who take daily multivitamins can significantly improve their health. In fact, an article published in the Journal of the American Medical Association (JAMA) recommends that all adult Americans take a vitamin supplement. Look for solid doses of vitamin supplement. Look for sol doses of vitamins and especially minerals. Multivitamins designed to be taken once a day are often woefully deficient in calcium, magnesium, and potassium. The only mineral a man should avoid is supplemental iron. Iron should only be in formulas for women prior to menopause. Men over 50 get all the iron they need from food and too much iron can cause health problems.
Look for men’s multivitamins that contain lycopene in the formula. Lycopene is the pigment that makes tomatoes red. The redder the tomato, the more lycopene is present. Numerous studies have shown that when men have high lycopene levels in their blood, they have a much lower risk of heart disease, age-related macular degeneration (a leading cause of vision loss) and prostate cancer.
Other important considerations are antioxidant blends, especially fruit- and tea-derived extracts; ginseng for energy and stamina; and digestive enzymes to aid in absorption and compensate for age-related decreased enzyme levels.
In fact, years of research has shown the foods a man chooses to eat (or not to eat) can have a profound impact on the health of his prostate gland. Because of this close nutritional link, prostate cancer may be the most preventable type of non-smoking related cancers.
Q. Aside from taking a quality multivitamin for general health, what nutritional supplements prevent and treat prostate cancer?
A. Six vital and all-natural nutrients can prevent prostate cancer from developing and even help fight the disease.
When men are exposed to excess levels of hormones, their risk of prostate cancer increases. A natural substance found in fruits and vegetables called calcium D-glucarate (or CDG), helps men’s built-in detoxification systems get rid of these harmful excess hormones.
This antioxidant has powerful effects on the prostate gland. In a recent study, researchers recruited 974 men to take part in a large clinical trial to determine if selenium could prevent cancer. The researchers found that selenium cut the rate of prostate cancer by 63%!
Green tea is the most widely consumed liquid in the world, after water. Men in
For many years, maitake mushrooms, or dancing mushrooms, have been linked to good health in those who eat them. That’s because maitakes contain an important compound called D-fraction. A recent study showed that maitake D-fraction destroyed 95% of human prostate cancer cells in lab experiments.
Promising preliminary reports demonstrate that lycopene can actually kill prostate cancer cells, so there has been an explosion of lycopene and prostate cancer research.
Q. What exactly happens to men’s hormones as they get older?
A. Just as women experience significant hormonal changes as they age, so do men. In fact, the term andropause has been used to describe men’s mid-life changes. Similar to menopause in women (where the decline of estrogen causes a myriad of symptoms), andropause in men signals the slow decline of testosterone, the chief sex hormone in men. While estrogen levels decline faster and more abruptly in women than testosterone levels do in men, testosterone decline can cause a number of unpleasant symptoms. These include abdominal weight gain, hair loss, reduced energy and sex drive, heart disease, and prostate enlargement. Whether a man labels these age-related changes as andropause or just the consequences of aging, most men will unfortunately experience some or all of them as their birthdays mount.
Q. So, is there a supplement that can give me the hormone level of a 20 year old?
A. Sadly, no, at least not yet! But there is a nutrient that can help the testosterone in a man over fifty “behave” more like a younger man’s testosterone.
A study that took place at the
The secret of DIM’s prostate cancer prevention is its ability to metabolize estrogen. While estrogen is generally thought of as a “female” hormone, a precise ratio of testosterone-to-estrogen is needed to maintain a man’s healthy sexual response, effective sexual function (erection of the penis and intercourse), strong bones and muscles, viable sperm, and a well-functioning prostate gland. As men enter their fifties, this ratio begins to change.
When men take DIM, however, their estrogen metabolism improves, testosterone metabolism accelerates, and the unwanted conversion of testosterone into estrogen is eliminated. This results in higher testosterone levels, similar to those seen in young men. As a result, DIM may speed weight loss, reduce prostate gland enlargement (benign prostatic hyperplasia or BPH), and help men over 50 feel stronger and leaner.
Some supplements on the market today contain indole-3-carbinol (I3C), a precursor to DIM. However, I3C is unstable and requires activation in the stomach to be converted into DIM. This means I3C must be taken at a much higher amount and can undergo unpredictable and undesirable chemical reactions in your stomach and colon. DIM is by far the preferred supplement.
Q. What is saw palmetto? Does it reduce symptoms of Benign Prostate Hyperplasia (BPH)?
A. Yes it does and very effectively too. Saw palmetto is a small palm tree native to
The prostate gland is about the size of a walnut and is located below the bladder and in front of the rectum. It wraps around the upper part of the urethra and its primary job is the production and storage of semen, the milky fluid that nourishes sperm. BPH is one of the most common health conditions in older men. Half of all men aged 40-60 and more than 90 percent in men over 80 have BPH. BPH causes the prostate gland to enlarge, putting pressure on the urethra.
Men have trouble starting or maintaining a stream of urine, find they can’t completely empty their bladders, and have to urinate frequently, even during the night. They may also have episodes of uncontrollable dribbling or complete loss of urine. BPH is caused by the conversion of estrogen to a very potent form of testosterone called, dihydrotestosterone (or DHT). When prostate cells are exposed to DHT, they multiply in number and get much larger.
BPH rarely improves. It most often remains the same for years or gets gradually worse. The need to continually urinate, interrupted sleep, dribbling, and loss of urine can significantly interfere with a man’s quality of life. Prescription medications that have been developed to treat BPH are only partially effective. And surgical removal of the prostate gland may result in even more persistent urinary incontinence and the inability to achieve an erection (ED).
However, saw palmetto berry extract relieves the symptoms of BPH by inhibiting the production of DHT. And, in study after study after study, saw palmetto caused none of the side effects that happen with prostate surgery or medications.
Q. There seem to be plenty of ads for supplements that claim they make men into Sexual Superheroes. Is there an “honest” nutritional supplement to help me sexually?
A. That’s a very good observation. And yes, there are honest nutritional supplements for men’s sexual health.
Sexual intimacy is an important, complex, and lifelong need. It makes us feel better physically and mentally and adds to our sense of security, belonging, and self-esteem. But just like other changes that happen to men as they get older, men’s sexual response most often changes, too. Declining testosterone levels, changes in blood flow to the penis, certain medications that older men are prescribed, and the presence of diabetes or heart disease can all affect men’s ability to engage in sexual activity.
When men have a chronic inability in obtaining and/or maintaining an erection, it’s called erectile dysfunction (ED). While ED is not an inevitable part of getting older, it does occur more frequently as men age. About 5% of 40-year-old men have ED, but more than 23% of 65-year-old men have difficulty maintaining erections.
The development of prescription medication Viagra (sildenafil citrate) has revolutionized ED treatment. When a man is sexually stimulated, Viagra helps the penis fill with enough blood to cause an erection.
Like all medicines, Viagra can cause some side effects, including headache, flushing of the face, and upset stomach. But because Viagra is a prescription medication, it requires a visit to a licensed healthcare practitioner. For many men, telling anyone (even a professional) that they are having trouble getting or keeping an erection is simply too embarrassing. Viagra is also fairly expensive and many older men do not have prescription drug health insurance.
These reasons may explain that while an estimated 30 million men in the United States – 10% of the male population – experience chronic ED, as few as 5% of men with chronic ED seek treatment.
Not every man can take Viagra, either. Men who use nitrate drugs, often used to control chest pain (also known as angina), must not take Viagra. This combination can cause their blood pressure to drop to an unsafe or life-threatening level. Men with serious liver and kidney problems who take Viagra must be monitored closely for possible serious side effects.
The good news is there is a nutritional supplement that’s formulated with vitamins, herbs, and glandular products that targets male sexual organs. The formula contains vitamin E, liver fractions, wheat germ, beta-sitosterol, and herbal extracts of muira puama, Mexican damiana, saw palmetto, cola nut, ginseng, and ginkgo biloba.
Vitamin E is a powerful antioxidant and men’s testicles, adrenal glands, and pituitary glands need high levels of this fat-soluble vitamin for proper functioning. Extracts of Muira puama, Mexican damiana, and cola nut have been studied for their beneficial effects on male hormones.
Study of ginkgo in sexual response came about when a patient in a nursing home who was taking the herb for memory enhancement noted that his erections were improved. Since then, study of ginkgo has shown it helps blood flow to the penis. Sexual response research in one ginkgo study showed that 76% of men taking ginkgo experienced improved sexual desire, erections, and orgasms.
While other nutritional supplements sold to improve sexual stamina often make outrageous claims, reputable manufacturers rely on science and results to sell their products.
An important note
Most often sexual problems are simply part of the aging process. They can also be signs of serious health problems. If the use of nutritional supplements for two months does not improve your erections, you do need to see your healthcare practitioner. Almost all practitioners understand how difficult this problem is for men to discuss and are experienced in getting the information as quickly and as painlessly as possible.
No man has the power to stop the passage of time. But every man has the power to make aging more healthy and less harmful. Research conducted on men who live to be 100 and beyond, has determined that those who reach extreme old age do so by avoiding ill health, rather than by enduring it. As I like to remind my patients, “Age is not determined by years, but by function.” And it’s never too late for men to detour around the major illnesses of getting older. With good nutrition, healthy habits, and high quality nutritional supplements, the best years of a man’s life can absolutely and positively be those he spends in his 70s, 80s and even his 90s.
Folic Acid: Strengthening the Immune System in the Elderly
January 09, 2006 09:38 AM
Folic Acid: Strengthening the Immune System in the Elderly
By Greg Arnold, DC, CSCS, December 20, 2005, abstracted from “Dietary folate improves age-related decreases in lymphocyte function” in the January 2006 issue of the Journal of Nutritional Biochemistry Recent research has elucidated health-promoting roles for folic acid beyond that of insuring normal development of the fetus. In addition to helping decrease neural tube defects,1 folic acid can also help treat inflammatory bowel disease 2 improve memory 3 and help decrease an amino acid in the body, homocysteine,4 that increases heart disease risk.5 Now a new study 6 has found another way that folic acid can help us age more Gracefully: by helping strengthen our immune system. Recognizing the importance of nutrition in the overall health of the immune system 7 and knowing that certain types of immune system cells, called “T cells”, decrease with age,(8,9) researchers fed 11-month-old and 23-month-old male rats either a control diet or a diet fortified with 35.7 mg per kg of folic acid for three weeks. Researchers found “a significant” increase in immune system strength in the folic acid group, specifically that of increased T cell levels, other immune system proteins called IL-2, IL-4, and anti-cancer proteins called “tumor necrosis factor”. While the study reaffirmed the immune system’s weakening with increasing age, the researchers concluded that “supplementing…with additional folate improves [immune system function] and that dietary folate requirement may be higher in the older population than in the younger population to support immune functions.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website www.CompleteChiropracticHealthcare.com Reference:
Your Cells Supercharge Your Cells
December 20, 2005 11:30 AM
Your Cells Supercharge Your Cells
The differences between aging and growing old are poles apart. Sure, they may sound similar in nature. But when you think about it, the two are as different as night and day. Growing old is about retirement and travel and enjoying what you’ve worked an entire life for. Aging, on the other hand, summons images of wrinkled skin, brittle joints, cloudy minds and medicine cabinets full of prescriptions. It’s safe to assume that the majority of us want to look, live, and feel better as we grow old. Not the opposite. Many of us are on the right track - committed to a healthy lifestyle that includes regular exercise and a well-balanced diet. And yes, these do serve as a solid foundation for good health during our golden years. It is our cells, however, that ultimately determine who grows old, and who just ages.
Still, slowing the proverbial hands of time is not all about health clubs and organic produce. If you want to grow old Gracefully, you must nurture the ten trillion cells that defi ne you physically. Why? Because these cells are constantly under attack by free radicals - unstable molecules that either lack, or have an unpaired number of electrons. They scour the body in search of stable cells, and do whatever they can to rob them of their electrons, a process more formally known as oxidation. Considering that it’s environmentally impossible to completely avoid contact with the billions of airborne toxins that cause free radicals, the only other option is to safeguard your healthy cells. Making the commitment to a healthy lifestyle is the fi rst step in the process, and can be accomplished by eating healthier foods, exercising on a regular basis, and paying close attention to what you are exposed to environmentally.
The next step is to nourish and protect your cells. The best way to do this is to consume foods that are rich in antioxidants and other cell-friendly nutrients. Unfortunately, this task is often much easier said than done. Today’s average adult is busier than ever, making it far more diffi cult to consume fresh, unprocessed meals 100% of the time. This does not, however, imply that all hope is lost. Over the years, the nutritional sciences have made stunning advances that afford you the opportunity to live your life while still safeguarding the integrity of your most basic building blocks. Here are a few of the best.
Antioxidants work at the cellular level to paralyze the free radicals that cause oxidation throughout the body. Some of today’s most popular nutrients and dietary supplements fall into this category. They include vitamins A, E, and C, Selenium, Zinc, Alpha Lipoic Acid, Lycopene, Lutein, CoQ10, in addition to a host of others. And though similar in function, each of these free radical fi ghters has a unique role within the body.
Take CoQ10 for example. It’s present in every cell of the body, and is especially important for cardiovascular support. Lutein has been used extensively to prevent oxidation in the macular regions of the eyes. Zinc is a powerful immune system booster that has become extremely popular during cold and fl u season. Alpha Lipoic Acid is both fat and water soluble, and is commonly referred to as the “universal” antioxidant based on its ability to quench free radicals anywhere in the body.
Immune Boosting Herbs
Herbs such as Astragalus, Olive Leaf, Rhodiola, Echinacea, Panax Ginseng and Ashwaganda have been used for centuries to help support healthy cells and strong, responsive immune systems. They’ve also been shown to exhibit natural synergistic effects when used together. Today, they remain one of the most popular ways to naturally promote all-around wellbeing. When it comes to supporting healthy cells, NOW is pleased to offer one of the best selections of antioxidants, herbs and immune support formulas. Be sure to look for these and other great products at fi ne health food retailers, nationwide.*
OPCs (proanthocyanidins) are high-powered polyphenol antioxidants that belong to the fl avonoid family. Grape seed extract, pine bark extracts such as pycnogenol and enzogenol, bilberry, gingko biloba, resveratrol and others all fall into this category. Research continues to suggest that OPCs work in the same manner that traditional antioxidants do, however their ability to eradicate free radicals is much greater and more versatile. Equally appealing, OPCs can easily cross the blood barrier of the brain to help protect brain and neural tissues from the damage caused by oxidative stress.
Throughout history, many civilizations have relied on organic mushroom extracts to encourage wellness. What we know now is that mushrooms such as Shiitake, Maitake, Reishi and others are rich in 1,3 Beta-glucans - soluble fi ber compounds that help support both innate and adaptive immunity. In addition, the active compounds in some mushrooms have been shown to stimulate the production of microphages, T cells, and other natural killer cells. These biological warriors serve at the front line when it comes to responding to bacterial attacks. They are of immeasurable value to the immune system, though drastically lacking in today’s average diet. In just the past few years, more and more healthconscious individuals have learned fi rst-hand how benefi cial they can be in the preservation of healthy cells.
7-Keto - The Key to Healthy Aging
June 21, 2005 05:05 PM
The global population is aging at an alarming rate and causing an explosion in health care costs, insurance premiums, cosmetic surgery and more. In the U.S. alone, more than one million baby boomers are expected to live to 100 years of age or older. This increased life expectancy presents a whole new set of health concerns that the medical community has not had time to address, since there is a greater need to care for age-related health problems in this ever-growing elderly population.1
Aging and the Decline in Vital Nutrients
We all grow old at the same rate but people age at different rates. Aging is a process of gradual changes that occur to varying degrees in each of us. Interestingly, the aging process is composed of different components and interactions, some of which can be impacted. One such component is the declining level of essential biological compounds, which causes our bodily functions to slow and become dysfunctional. Our organs don?t work efficiently, our immune system becomes lazy, we lack energy, our metabolism drops and we gain weight easily.1 7-oxo DHEA (7-Keto™) is a naturally occurring compound that declines with age.2 Replacing this key metabolite helps promote a healthy immune system and maintains resting metabolic rate at levels that accelerate weight loss during standard weight reduction programs.
Aging and a Healthy Immune System
Numerous changes occur in the immune system with advancing age, probably contributing to decreased immune responsiveness. Although all segments of the immune system are affected, investigators have most consistently identified declines in cellular or T-cell mediated immune function in the elderly. The decline in T-cell immune function is generally associated with an increased susceptibility to foreign organisms. For example, individuals with age-related declines in cellular immunity have an impaired response to vaccinations, making them more susceptible to health imbalances even though they have had their shots. In a clinical study presented at the Federation of American Societies for Experimental Biology meeting in April 2004, the effect of 7-Keto on elderly immune function was evaluated. Healthy elderly adults were given 7-Keto orally twice daily over a period of one month. The study revealed that 7-Keto augmented several key T-cell mediated immune function parameters compared to placebo administration.4
Age-Related Weight Gain
Age-related weight gain and obesity are approaching epidemic proportions in our country.5 Weight gain is a disorder of energy balance involving energy intake and/or expenditure. Low energy expenditure, a drop in resting metabolic rate (RMR), is a challenge during most weight loss attempts due to age, calorie restriction, lack of physical activity or a combination of factors. RMR represents 60% of total daily energy expenditure. Maintaining a higher RMR as we age and during weight reduction programs helps us achieve and maintain a normal weight. Furthermore, compounds with the thermogenic potential to achieve even minimal increases in daily energy expenditure of 2-3% may have clinical relevance in preventing the decline in RMR with calorie restricted diets or weight loss, and in decreasing the risk of regaining weight. 7-Keto, a non-stimulant thermogenic compound, has been shown to significantly increase energy expenditure in humans.6 A recently completed clinical study, also presented at the Federation of American Societies for Experimental Biology 2004 meeting, revealed that administration of 7-Keto to overweight adults in conjunction with a calorie restricted diet effectively reversed the decline in RMR normally associated with dieting. Obese participants following a calorie-restricted diet demonstrated a 5.4% increase in daily RMR with 7-Keto.7 The magnitude of the increase in RMR by 7-Keto is clinically relevant, and represents a promising agent for enhancing thermogenesis and weight loss in obese individuals on calorie-restricted diets. Additionally, 7-Keto has been shown in two confirmatory published clinical studies to result in three times more weight loss compared to diet and exercise alone. It has a favorable side effect profile and is easy and convenient to take.8,9 Our life expectancies will likely be longer than those of our parents, and our quality of life during those years will depend on how well we take care of our bodies now. Undoubtedly, the science of aging will give rise to new and exciting technologies to help us age more Gracefully and healthfully. Maintenance of healthy immune function is keenly needed for improved quality of life in the elderly. Dietary manipulation and supplementation has been identified as a method of immune system renewal, and supplements such as 7-Keto may play an important future role as immune system modulators. Moreover, the addition of 7-Keto to any weight loss program will offer vital support of energy expenditure and help with the attainment of a manageable and healthy weight into our older years.
1. 1995 White House Conference on Aging, ?Executive Summary: The Road to an Aging Policy for the 21st Century," February 1996: 17-18. 2. Marenich LP. Secretion of Testosterone, Epitestosterone, Androstenedione, and 7-Keto-Dehydroepiandrosterone in Healthy Men of Different Ages. Prob Endokrinol. 1979; 25(4): 28-31. 3. Ginaldi L, De Martinis M, D?Ostilio A, Marini L, Loreto MF, Quaglino D. Immunological Changes in the Elderly. Aging 1999; 11(5): 281-286. 4. Zenk JL, Kuskowski MA. The Use of 3-acetyl-7-oxo-dehydroepiandrosterone for Augmenting Immune Response in the Elderly, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 5. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and Trends in Obesity Among US Adults. 1999-2000. JAMA 2002;288:1723-1727. 6. Astrup A. Thermogenic Drugs as a Strategy for Treatment of Obesity. Endocrine 2000;13(2):207-212. 7. Zenk JL, Leikam SA, Kassen LJ, Kuskowski MA. A Prospective, Randomized, Double Blind Study to Evaluate the Effect of HUM5007 and 7-oxo DHEA on Resting Metabolic Rate in Overweight Adult Men and Women on a Calorie Restricted Diet, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 8. Kalman DS, Colker CM, Swain MA, Torina GC, Shi Q. A Randomized, Double-Blind, Placebo Controlled Study of 3-Acetyl-7-Oxo-Dehydroepiandrosterone in Healthy Overweight Adults. Current Therapeutic Research 2000;61: 435-442. 9. Zenk JL, Helmer TR, Kassen LJ, Kuslowski MA. The Effect of 7-Keto Naturalean on Weight Loss: A Randomized, Double-Blind, Placebo-Controlled Trial. Current Therapeutic Research 2002; 63:263-272.
John L. Zenk, M.D., is Chief Medical and Scientific Officer for Humanetics Corporation and President and Medical Director of Minnesota Applied Research Center, both located in Eden Prairie, MN. He has spoken nationally and internationally on the subjects of integrating conventional and complementary medicine, anti-aging technologies, evaluating the effectiveness of alternative medicine, and dietary supplement research and development. He is author of the book Living Longer in the Boomer Age, and co-author of the book Age Wise and is a frequent contributor to national media. He has served as Principal Investigator for 15 controlled clinical studies, three of which were recently published in national peer-reviewed journals, and has presented abstracts at the 11th World Congress for Food Science and Technology and the Federation of American Societies for Experimental Biology.
June 11, 2005 05:04 PM
Power Protein by Joanne Gallo Energy Times, August 4, 1999
Chances are, if you've been trying to lose weight, build muscle, or increase your energy levels, then you've been hearing about protein. This essential nutrient has stolen the spotlight of the health industry as the alleged key to vitality and a solid physique.
With books like Protein Power (Bantam) and Dr. Atkins' New Diet Revolution (Avon) firmly implanted on The New York Times bestseller list, and protein bars and shakes growing in popularity, more people than ever are seeking to tap into the power of protein.
But before you go on an all-out protein-blitz, how can you decide what's best for you?
The Purpose of Protein
No doubt about it, protein performs a variety of roles. First and foremost, it is used to manufacture and repair all of the body's cells and tissues, and forms muscles, skin, bones and hair. Protein makes up the connective tissue that forms the matrix of bones; keratin is a type of protein used to make hair and nails.
It is essential to all metabolic processes; digestive enzymes and metabolism-regulating hormones (such as insulin, which influences blood sugar levels) are all made of protein. This nutrient also intricately takes part in transport functions: Without sufficient protein the body cannot produce adequate hemoglobin, which carries nutrients through the blood. Lipo-proteins are fat-carrying proteins which transport cholesterol through the bloodstream.
Protein helps regulate fluid and electrolyte balance, maintaining proper blood volume. Immunoglobulins and antibodies that ward off diseases are also comprised of protein.
Any protein that you eat that is not utilized for these purposes is stored as fat, although some may be broken down, converted to glucose and burned for energy. This can occur during intensive workouts, or when the body runs out of carbohydrates from the diet or glycogen from its muscle and liver stores.
"Even though the body can depend on the fat it has stored, it still uses muscle protein, unless it is fed protein as food," explain Daniel Gastelu, MS, MFS, and Fred Hatfield, PhD, in their book Dynamic Nutrition for Maximum Performance (Avery). "When dietary circumstances cause the body to use amino acids as a source of energy, it cannot also use these amino acids for building muscle tissue or for performing their other metabolic functions."
One can see why it is so important to eat a sufficient amount of protein daily in food, shakes or bars. Without it, bone tends to break down, the immune system can become impaired, and muscle strength drops as the body uses up muscle protein for energy.
Proteins are built of chains of amino acids, and 20 different kinds of these building blocks are necessary for protein synthesis within the body. Eleven of them can be manufactured by the body through a process called de novo synthesis; these are referred to as non-essential amino acids. The other nine, which must be obtained from the diet, are known as essential amino acids. (Although some amino acids are called "non-essential," in actuality they are vital: The body needs all 20 amino acids to function properly.)
Some of the more familiar non-essential amino acids include: n Carnitine helps remove fat from the bloodstream n Arginine helps burn sugar Essential amino acids include: n L-tryptophan, a precursor of the neurotransmitter serotonin, helps create calm moods and sleep patterns n L-lysine, required for the metabolism of fats n L-methionine a component of SAM-e (a supplement intended to relieve depression and arthritis, see p. 45)
The body forms and destroys protein from amino acids in a constant cycle of synthesis and degradation. You must consume protein regularly to replace the lost amino acids that are oxidized when protein is broken down and used for fuel. The amount of amino acids lost each day depends on what you eat and how much exercise you do.
Athletes vs. Weekend Warriors
Protein intake in the general population is still adequate, notes Gail Butterfield, PhD, RD, director of Sports Nutrition at Stanford University Medical School. "But we're learning that what is true for the general population may not be true for the athletic population," she says. "With heavy training there is greater protein degradation and you need to increase your intake. Thus, protein requirements are higher for athletes than regular people."
Also, if you diet or restrict your eating in any way, you may also not be getting enough protein.
Certainly, if you work out, eating protein is important. Providing four calories of energy per gram, protein keeps blood sugar steady during exercise. After exercise, it helps replenish and maintain stores of glycogen (stored muscle fuel) and decreases the loss of amino acids, as recent research has shown (J Appl Physiol 81 (5), Nov. 1996: 2095-2104). Lab studies in animals show that protein consumed after you run, lift weights, bike, etc..., helps stimulate muscle growth (Jrnl of Nut 127 , June 1997: 1156-1159)
High-protein diets are frequently touted to promote weight loss and increased energy. One of the most influential: the so-called 40-30-30 formula, developed by Barry Sears in his book The Zone: A Dietary Roadmap (HarperCollins), which describes a diet whose calories are 40% carbohydrates, 30% protein and 30% fat. The rationale: when you eat too many carbohydrates, your body uses these starches for energy instead of burning body fat. A high protein diet is supposed to keep your blood sugar balanced and stimulate hormones that burn body fat instead of carbohydrates for energy.
Other fitness experts such as Sherri Kwasnicki, IDEA International Personal Trainer of the Year of 1998, say that while protein is a necessary component of any diet, extreme high-protein plans aren't necessary for recreational fitness buffs. However, she notes that maintaining muscle mass is the key to aging Gracefully, and getting enough protein is critical for that.
Many people today won't eat meat and dairy for ethical reasons, or to avoid the antibiotics and other chemicals in the raising of poultry and cattle. But that doesn't have to prohibit adequate protein intake. All soybean products, including tofu and soymilk, provide complete proteins, which supply ample quantities of all the essential amino acids.
In the past vegetarians were told to combine particular foods to make sure they consumed all the essential amino acids at each meal. (For example, beans with either brown rice, corn, nuts, seeds or wheat forms "complete" protein.) Today, diet experts aren't so picky. Eating a variety of plant-based foods throughout the day is just as effective as combining them at one meal.
Vegans who avoid all animal products should eat two servings at sometime during the day of plant-based protein sources, such as tofu, soy products, legumes, seeds and nuts.
The newest sources of protein are bars and shakes, which are growing steadily in popularity. Protein bars now constitute about 12% of the so-called energy bar market, with sales increasing about 38% per year. These bars generally provide at least 20 grams of protein, including soy and whey protein and calcium caseinate (milk protein). The benefits: bars supply protein along with carbohydrates for energy; protein powders, on the other hand, provide quickly digested, easily absorbed amino acids.
Edmund Burke, PhD, author of Optimal Muscle Recovery (Avery), suggests "If you need extra protein, you may benefit from the convenience of a mixed carbohydrate-protein supplement... choose a supplement that's healthy and low in fat."
Amino acid supplements are also growing in popularity, reported to build muscle and burn fat, or improve mood by boosting brain neurotransmitters. The amino acids glutamine, phenylalanine, tyrosine and 5-HTP (a form of tryptophan) are all used to boost spirits and enhance brain function.
And if you still ponder the merits of those high protein diets, do keep in mind that protein may be better at controlling hunger than carbohydrates or fat since it steadies blood sugar, so it may help you stick to a reduced-calorie plan. But excess protein can't be stored as protein in the body: It is either burned for energy or converted to fat. And carbs are still the body's top energy source, so forgoing too many can leave you tired and sluggish.
Still, with so many vital functions-and a variety of sources to choose from-you can't afford to not explore the benefits of protein.