Search Term: " Grant "
New gut bacteria discovered: Scientists are researching a strainthat shows potential for enhancing weight loss
March 20, 2019 12:52 PM
According to Dr. Gilberto Flores, there is a bacteria called Akkermansia muciniphila that may have the ability to jump-start weight loss. Dr. Flores and other medical experts have an inkling that Akkermansia muciniphila is actually a probiotic, but there still needs to be additional research in order to determine if this is true or not. It has been proven, however, that those who have higher levels of Akkermansia muciniphila within their bodies have a less chance of being overweight or obese.
"If we’re lucky, we can soon learn more about a certain kind of gut bacteria that might have various health benefits such as preventing weight gain."
Read more: https://www.naturalnews.com/2019-01-06-gut-bacteria-shows-promise-for-weight-loss.html
3 Nutrients that reduce excessive amounts of the stress hormonecortisol
February 28, 2019 08:47 AM
In the appropriate quantities, the stress hormone known as cortisol is actually beneficial to our bodies. It's when these levels rise to an abnormal level that they can become detrimental to our bodies. Fortunately, there are many natural nutrients that can aid in the reduction of cortisol levels in order to get them down to a more efficient level. Foods that are high in omega-3 fatty acids, for instance, are great sources of health benefits including cortisol regulation.
"Too much cortisol in the body, which can be attributed to stress, lack of sleep, infections, or white light exposure, can become a problem since it depletes the adrenals that also produce other hormones."
Read more: https://www.naturalnews.com/2019-01-13-3-nutrients-that-reduce-excessive-stress-hormone-cortisol.html
Another benefit of aloe vera: It reduces fasting blood glucose
February 04, 2019 09:52 AM
Blood sugar regulation is imperative for all individuals, but especially those who are living with conditions such as diabetes. While many patients opt for pharmaceutical interventions to help maintain their glucose levels, natural alternatives such as aloe vera are showing to have a positive impact on sugar regulation. Aloe vera through oral consumption was able to reduce the glucose levels of diabetic patients by 46.6 milligrams while fasting. These results show that aloe vera could be exceptionally beneficial to those dealing with endocrine issues.
"Researchers at David Grant Medical Center at Travis Air Force Base in California aimed to verify the effectiveness of oral consumption of aloe vera on reducing fasting blood sugar and HbA1c."
Read more: https://www.naturalnews.com/2019-01-23-aloe-vera-reduces-fasting-blood-glucose-2.html
Help ward off infections and improve your immune system withoregano oil
November 13, 2018 08:51 AM
There are a lot of ways in which you can help enhance your immune system. Not everyone is blessed with a rock solid immune system in the sense that you can just fight off anything that comes your way. If you are feeling bad, your immune system will help you feel better over time. However, studies are showing that oregano oil can help sharpen your immune system. It is said to be very good to ward off infections.
"Oregano, the fragrant herb commonly used to flavor pasta and meat dishes, is renowned for its versatility in the kitchen. But did you know that it can also be transformed into an herbal oil with a wide range of benefits?"
Read more: https://www.healthnutnews.com/help-ward-off-infections-and-improve-your-immune-system-with-oregano-oil/
Scientists call on feds to allow research on CBD for pets
December 10, 2017 03:59 PM
Veterinarians, researchers and pet owners are looking to loosen federal regulations on the use of marijuana products to help treat sick animals. Medical issues in dogs, such as epilepsy, arthritis, anxiety, loss of appetite and inflammation could potentially by helped by marijuana-based drugs and extracts.
Some people are already using marijuana extracts on their animals, such as those containing CBD, which is an element of marijuana that is not psychoactive. However, such extracts continue to be listed as Schedule 1 drugs by the Federal Drug Enforcement Administration, even when they contain little or no THC. THC is the active component in marijuana that causes intoxication.
The Food and Drug Administration has warned that marijuana products for pets sold in animal hospitals or online pet stores are illegal, since such drugs are unapproved. The FDA has suggested it will pursue legal action against those in violation of the law.
However, the policy-making body of the American Veterinary Medical Association, in conjunction with two group councils, is considering making a recommendation to the DEA for marijuana to be declassified as a Schedule 1 drug in order to enable research for both animal and human medical purposes. Declassification could also help prevent pet owners from accidentally overmedicating their animals in the absence of proper guidance from a medical professional.
In September, Republican senator Orrin Hatch of Utah introduced a bill that would facilitate research on use of marijuana-based medications, concurring that the drug is over-regulated, although he continues to oppose recreational use of the drug,.
Some veterinarians note that without sufficient evidence, it remains unsafe to use marijuana products on animals, with concerns about potential toxicity.
Yet researchers are continuing to wait for clearance to proceed on various relevant studies, such as use of marijuana for dogs with osteoarthritis, pruritis and epilepsy. Some research on use of products with CBD has been stopped until federal approval is granted. Gaining approval has been difficult due to government requirements, which continue to be an obstacle to moving forward.
"The concern our membership has is worry about people extrapolating their own dosages, looking to medicate their pets outside the realm of the medical professional"
Read more: https://www.aspentimes.com/news/scientists-call-on-feds-to-allow-research-on-cbd-for-pets/
Why you need essential oils in your household for the fall and winter season
October 14, 2017 01:14 PM
Fall is coming and after that it will be winter. If you have ever wanted to try essential oils now will be a good time. This gives many reasons why this is a good time to use them. They can do a lot in the home. They can help with health, cleaning, ad more. Those who have tried them usually end up wishing they had done so much earlier because of all the benefits they reap.
"Some of the benefits of essential oils during this time are:
Natural (and naturally fragrant) cleansing of the indoor air Helps supports healthy immune function Uplifts mood, and supports emotional well-being Supports muscle and joint health Improves skin health Supports the respiratory system Supports digestive balance May help improves sleep"
Read more: https://www.naturalnews.com/2017-10-09-why-you-need-essential-oils-in-your-household-for-the-fall-and-winter-season.html
Research pilot explores industrial hemp
September 07, 2017 12:14 PM
Although the Washington state legislature has allowed hemp to once again be grown in the state, there are still some questions and uncertainties about growing the product. For now, those growing hemp are doing it for research purposes to monitor what the future growers will need it to do in order to create an industrial hemp harvest. Despite the four different types of licenses being granted, there is still some caution because of the plants close relationship it to marijuana. Hopefully some restrictions will change and beneficial aspects of the hemp can be produced, such as CBD oil.
"Hector Castro, Olympia-based communications director for the WSDA, says although the program is new, it’s generated a lot of interest from farmers and others who see potential in harvesting hemp."
Read more: https://www.spokanejournal.com/local-news/research-pilot-explores-industrial-hemp/
9 Health Benefits Of Hibiscus
June 30, 2017 09:14 AM
Hawaii is an island known mostly for its luaus and gorgeous views, Hawaii is also covered with beautiful hibiscus trees. These hibiscus flowers while beautiful, hold many not well known health benefits. The hibiscus flower is mostly used to make a tea known as "sour tea" or made into a topical application. Hibiscus is loaded with antioxidants, these antioxidants help combat free radical damage that lowers inflammation in the body. The flowers is also filled with nutrients and help boost your immune system especially during cold and flu season. Hibiscus also has many other benefits including lowering blood pressure and cholesterol, helps improve your mood and digestive system. When applied to your skin it will make it more firm and great at moisturizing as well. All around hibiscus has many health benefits and would be very beneficial for your body.
"not only are hibiscus flowers beautiful and fragrant, they also have a wide array of health benefits."
Read more: http://www.thealternativedaily.com/health-benefits-of-hibiscus/
Cancer-killing Dandelion Tea Receives $157K Research Grant
May 18, 2017 08:44 AM
Chronic monocytic myeloid leukemia, a cancer of the blood, has been shown to respond to respond to dandelion root extract in clinical studies. Siyaram Pandey, a biochemist at the University of Windsor, began studying its effects after an oncologist pointed out to him that patients of hers who drank dandelion root tea, were getting better. He developed a formula concentration the roots into a potent tea that has shown to treat cancer cells, while leaving healthy cells alone. His team has received a substantial research grant to continue their research.
"After other medical treatments for his leukemia failed he tried the tea. Four months later, he returned to the clinic in remission and has been cancer-free for three years."
Read more: http://www.healthnutnews.com/cancer-killing-dandelion-tea-receives-157k-research-grant/
how to get rid of ants naturaly
April 22, 2017 04:44 AM
Ants are a real problem for many homeowners. What do you do to get rid of them if you don't want to use harmful chemicals? There are many solutions with things you probably have around the house. Dust them with fraGrant talcum baby powder. They don't like this. You can also squirt vinegar on them, or make a less strong mix of water and vinegar. They also head away from cinnamon and black pepper, so sprinkle this where they are. Another solution is 50 percent Windex and 50% Ivory soap. Try some of these. They aren't harmful to your family and they just might work perfectly for what you need.https://www.youtube.com/watch?v=5mZI2E5tKjw&rel=0
"If you find a trail of them in your house or some scouts looking for food so they can bring the rest of their nest to enjoy it, just sprinkle the baby powder on the the ants and wherever they are coming from."
Fake weed: Why does government marijuana look so weird?
March 27, 2017 08:59 AM
The government, yet again, is trying to control/discourage research and development of products related to marijuana. Outlined here is how the only products available for research studies are outdated, ineffective, and poor quality marijuana plants. Most plants that are used are grown in outdated environments and conditions. In states where the plant is legal, it can't be used for research purposes. The product must be the sub-standard, government issued plants. People who could benefit from this research, should pay attention to, and follow-up on this report.
"Photographs of the government marijuana samples received by Sisley show a substance that bears almost no resemblance to commercial marijuana."
Read more: http://www.naturalnews.com/2017-03-23-fake-weed-why-does-government-marijuana-look-so-weird.html
Medical cannabis - The healing pros and cons
March 18, 2017 01:44 PM
Medical cannabis is becoming more widely accepted across the world as studies continue to show the phenomenal results patients have obtained with its use. There is no question that medical marijuana has an array of positive benefits associated with its use that you should know. But, are there disadvantages of using medical marijuana? Nothing is perfect, so it is only expected that some disadvantages exist. Learn more about both the pros and the cons of medical cannabis without delay.
"The use of medical cannabis is currently legal in 28 states, and proponents say the herb is changing lives by granting relief to people suffering from such problems as chronic cancer pain, multiple sclerosis, epilepsy, anxiety and sleep disorders."
Read more: http://www.naturalnews.com/2017-03-15-medical-cannabis-the-healing-pros-and-cons.html
How does CBD help with Seizures
December 19, 2016 10:28 PM
Seizures are the sudden changes in the brain's electrical activity. It usually affects how a person acts for a short period of time or appear. The symptoms of seizure include a loss of control and violent shaking. There can be several causes for the seizures. Anything that affects the brain's normal activity can lead to seizures. Several causes of seizures include injury to the head, fever, disease or even certain uses of medications. A person suffering from regular seizures due to brain disorder is called to be having epilepsy. Seizures can take different forms that affect many people in different ways, as some people call it electrical storms in the brain.
CBD has several therapeutic effects. Unlike THC, CBD has a less binding affinity to the CB1 and CB2, those are Cannabinoid receptors. Instead, CBD stimulates endogenous cannabinoid signal by suppressing enzyme fatty acid amide hydroxylase (FAAH). CBD helps in enhancing endocannabinoid by suppressing FAAH. CBD also opposes the action of THC at CB1 receptor, thus help to mute the effects of THC. CBD also stimulates 2-AG, that activates the CB1 and CB2 receptors, where CB2 receptors are predominant in the immune system and peripheral nervous system. It is found that CBD binds directly with 'G-protein' coupled receptors and other ion channels to Grant therapeutic effect. CBD is also known as the TRPV-1 stimulant that helps, CBD-rich Cannabis in the effective treatment of the neuropathic pain.
Here's How the Food Lobby Affects What We Eat
November 26, 2016 10:59 AM
Most people believe that fresh fruits and vegetables are the best choice for healthy food. Recent conferences with dieticians have been focusing more on prepackaged food as a healthy choice. Large companies at the conferences, such as Nabisco and PepsiCo, are trying to market their brands in a more healthy light. Many of these companies that are known for their less- healthy and high sugar products are trying to change the consumers’ views of them.
"Among the hundreds of exhibits, many focused on items like beans, eggs, strawberries and leafy greens."
Saturated fats and refined sugar linked to brain damage, encourage overeating
November 23, 2016 02:59 PM
You probably already know about the three basic types of food, what they're used for, and how these sources of energy can affect your body. and you probably already know that certain things are bad for you -- like saturated fats and refined sugar. But do you know just how bad for you these two are? In "Saturated fats and refined sugar linked to brain damage, encourage overeating", this article assesses the dangers...
"When it comes to weight loss, it's important to realize that saturated fats and refined sugar do more than just pack on the pounds."
Ginger root: a homemade remedy for stomach pain and nausea
November 17, 2016 05:41 PM
A fraGrant homemade remedy for an upset stomach is ginger. There are several properties that make ginger root a stomach pain soother. Researches have shown that ginger root has proved effective in getting rid of nausea while pregnancy. It is more effective than any anti inflammatory drug. Ginger root can alleviate the pain and discomfort in your abdomen in many ways. One gram of ginger taken in the form of tea, ale, salad, juice or soup is as efficacious as the anti-nausea drug, dimenhydrinate because it has lesser side effects. Ginger root is a better cure for nausea than vitamin B6. Ginger has reduced nausea due to chemotherapy in many cases.
The healing spice, ginger has anti-inflammatory properties which helps it in increasing the digestive juices, neutralizing the stomach, thus soothing the stomach pain. Ginger helps in the secretion of some digestive juices and enzymes that neutralize the stomach. The root of ginger contains two chemicals: gingerols and shogaols. These are antioxidants that reduce the free radical production, thus protecting the body from them.
When we use ginger root to treat stomach pain, these two chemicals soothe the intestinal tract, in order to prevent motion sickness and relieve the person from vomiting, stomach cramps, diarrhea and nausea. As the intestinal tract gets relaxed, the person is instantly relieved of pain. It causes elimination of any extra gas from the intestinal tract. Ginger root help in the quick flow of food in the stomach through the digestive tract by facilitating better absorption of nutrients. It aids in the production of bile, saliva and other gastric juices for better digestion and prevention of gas. The muscles are relaxed because of the phenols present in ginger root, that act like a sedative. Any over activity of stomach is prevented. The stomach cramps are prevented because ginger reduces the food from backing up in the digestive system. These phenols also help in quick movement of food and toxins in intestine and digestive system. Besides, ginger root helps in improving blood circulation and decreasing inflammation.
Improving Liver Health - Does NAC Help Improve Liver Health?
September 25, 2015 01:33 AM
All organs in our body have purposes why they exist. This includes our football size liver. Many people take their liver health for Granted. Since it is an internal organ, we do not see the actual effects of toxins and unhealthy lifestyle as they slowly destroy the liver. However, we might feel the results from time to time. Our liver has the size of a football, making it a star football player in our digestive system where everything passes through it. It cleanses the blood by taking away hazardous chemicals, converting the liquid into bile, which is then used to break down fat from the food we eat. The liver also stores glucose, a sugar that quickly boosts energy. So how do we take care of our liver?
How to Take Care of Liver Health
It is okay to enjoy and have fun, but to do it every day with a lot of alcohol is dangerous. Drinking too much alcohol leads to the swelling of liver cells.
Controlling what you eat and good amount of exercise will help you avoid non-alcoholic fatty liver diseases, a condition that might lead to severe liver damage.
There are some medicines such as Tylenol and cholesterol drugs that may hurt your liver when taken in uncontrolled doses. Also avoid taking medicines with alcohol, because they are not a good combination, or joining different drugs together.
Many studies say that liver diseases are caused by the lack of Glutathione or GSH in our body. That is why NAC comes to the rescue.
NAC is a small protein powerful to restore intracellular level of Glutathione or GSH, an effective antioxidant. The GSH is most needed by those who have liver diseases because it protects the liver against toxicity. When you are suffering from stress caused by a chronic liver disease, there is the reduction of glutathione, which is why there is a need to supplement it. NAC also helps to protect against present liver damages by reducing a wide range of chronic, deteriorating issues which include liver inflammation and impaired glucose control.
Taking good care of our liver health is like grooming a football superstar. Always watch out of the things you are doing to it.
Wintergreen Oil- Used For Pain, Arthritis, Headaches and More
February 26, 2014 09:06 AM
What is wintergreen
Wintergreen (Gaultheria procumbens) is in the heather family of organic plants and is local to North America. It is a little evergreen herb that develops just something like 6 inches high with thin crawling stems. It has hanging white blossoms which are accompanied via red berries. Local Americans used to bite the stems to build respiratory limit. Early American pilgrims had their youngsters bite the leaves for some weeks each one spring to avoid tooth rot and throughout the American Revolution, it was a substitute for Black Tea. They so reveled in the essence that it has proceeded right up 'til today as the character of root brewskie, mulling over gum and toothpaste. The oil hails from steam refining of the leaves and produces an in number, entering fragrance. The science of wintergreen is very nearly indistinguishable to that of birch .
Generally wintergreen has been utilized for respiratory conditions however the essential utilize as of late has been as a part of liniments and treatments for bulky issues, for example, lumbago, sciatica, neuralgia, myalgia, and so on it is known for its capability to diminish bone agony.
Check Out The Wonder Grain: Amaranth
February 02, 2014 07:48 AM
The wonder of amaranth
The wonder grain Amaranth has been known to humans for centuries. It was heralded as a staple in the diets of pre Columbian-Aztecs who heralded the plant is Granting them special powers. Unfortunately, when the Spanish Conquistadors arrived in the region, they outlawed the crop and went to great lengths to push its existence far from common knowledge. It has only resurfaced on the market in recent decades.
A broad and bushy plant, amaranth can grow to around six feet in height. It sports a bright and colorful flower head which contains an immense amount of seeds. It is not uncommon for a single plant to produce seed quantities around the 60,000 mark. The seeds are typically used in the creation of amaranth cereal or flour.
The plant itself is not technically a grain, belonging instead to the same plant family as beets, spinach and quinoa. This classification is the reason it offers nutritional benefits that are closer to those offered by darker, greener plants with more foliage rather than those of true grains. Amaranth plays host to a myriad of different nutrients, including vitamins, minerals, and amino acids. One amino acid in particular, lysine, which is generally present in fairly low levels in other grains, appears in a noticeably higher concentration here. Compared to wheat, Amaranth also carries four times as much calcium and double the content of iron and magnesium. It also boasts an exceptionally high level of protein.
Uses of amaranth
This miracle plant can be prepared with a wide variety of techniques. It can be simmered to produce a consistency not unlike porridge. It can also be mixed with other grains to create a dish that resembles rice. Traditionalists can also toss the grains in a skillet to be cooked like popcorn, producing a crunchy, almost nutty experience. While still not yet immensely popular and therefor sometimes harder to find, amaranth can be an excellent addition to any healthy diet.
Health Benefits Of Chamomile
December 03, 2012 07:56 AM
It is believed that ancient Egypt saw Chamomile as an effective cure for most illnesses. In the modern world too, this golden herb retains its healing properties and is used for treating many a disease and discomforts of the body. Most commonly, German chamomile blossoms are infused to prepare 'Chamomile tea' which is a fraGrant concoction full of medicinal properties. The tea can be combined with honey to enhance the taste.
Health Benefits Of Chamomile Tea Chamomile tea, supposedly, helps to bring about restful sleep. It is thus of great value for people suffering from insomnia and other sleep-related disorders. Due to its soothing and relaxing effects, it is generally taken before a person goes to bed. Since time immemorial, Chamomile has been considered a remedy for stomach ailments. Known to soothe gastric and bowel related problems, the herb is a blessing for people with stomach aches.
All in all, Chamomile helps facilitate the complete digestion process by promoting bowel movement. For women facing menstrual cramps and nausea every month, Chamomile tea comes as a welcome relief. Research indicates that regular consumption of Chamomile tea increases the level of glycine in the body. Glycine is a compound that controls muscular spasms, thus it tends to calm menstrual cramps. A healthy cup of golden chamomile tea has also been found to combat the morning sickness of pregnancy. However nothing has been proven till now to this effect. Some studies suggest that this wonder herb accelerates the wound healing process too.
Many researchers are of the belief that age-old Egyptians and Greeks used Chamomile flowers on wounds to speed up their healing time. Though there is no established evidence as such regarding this subject, history stands witness to the magical healing properties of Chamomile in more ways than one. Diabetes patients are also in for some good news concerning Chamomile tea. Many ongoing studies and surveys conducted worldwide are hinting at Chamomile playing a role in diabetes management.
Consumed regularly in the form of tea, the herb may arrest complications arising out of diabetes and may also prevent hyperglycemia. What's more, the golden herbal tea prepared from chamomile is caffeine-free and will not be addictive in any way. However, it is always a good idea to take professional advice before going all-out for Chamomile. Some people may display allergic reactions to the herb and suffer side-effects.
Therefore, it is best to try the herb first in small amounts before one decides to include chamomile tea in the daily routine of life. Besides its therapeutic uses, chamomile is being increasingly used as an ingredient in cosmetic products and is being considered a good friend of the skin. Since Chamomile is known to be a stress-buster, a cup of chamomile tea after a hectic work day might just prove to be the right beverage to save the evening. With its sedative, anti-inflammatory and anti-bacterial properties and benefits, Chamomile is sure to become more popular by the day. Used wisely, the golden herb is no less than gold itself.
What Can Chromium Picolinate Do In The Body?
July 23, 2011 03:15 PM
It is inevitable that health awareness and protection are very vital. It is also very crucial for us to take necessary measures and precautions to boost our guards from elements that could pose harm and threat to our very delicate body. If we just take these things for Granted, for sure, we will be paying for the consequences of our own actions. Fortunately, we are living in this generation where in many have already been discovered that we could utilize to help us achieve a health state that we have always wanted. Chromium Picolinate is one useful element that could help us control the blood sugar levels in our body. Therefore, it is deemed necessary especially for those that are suffering from diabetes mellitus.
Many experts would claim that Chromium is beneficial in reducing body fat as well as in improving muscle tone. With the array of benefits it is capable of offering the human body; its discovery could be considered as a miracle breakthrough in the field of medical science. However, there are still questions that lurk in the minds of many about chromium. Questions like “could chromium be the answer of our predicament with the very common diabetes mellitus?” Such question is surely expected because not all are fully aware about its importance therefore; its discovery is not yet wholly appreciated. Because of this, there is a great need to educate the populace about its benefits.
Chromium is an important trace mineral that is useful in the metabolism of carbohydrates hence; it could play a vital role in the regulation and metabolism of blood sugar. Other benefits of chromium would also include management of cholesterol, and hypertension. Chromium can be grasped from many food sources. But it is most abundant in true brewer’s yeast. The more common nutritional yeast though has chromium content but is not as high compared to that of a true brewer’s yeast. Chromium can also be found in grains and cereals. However, at the course of the refining process, most of the said mineral is depleted and lost. Beers also contain small amounts of chromium.
Many individuals who have good knowledge about chromium would really agree about the above mentioned benefits. As a matter of fact, a lot of dieters and health conscious individuals could really testify about the benefits of chromium picolanate especially in improving muscle tone, fat metabolism, and blood glucose level control. At present, there are a growing number of people who are already enticed to take chromium picolinate because of the irrefutable benefits it offers. Needless to say, we are the culprits of our own actions. Whatever health state we would grasp is surely the result of the things that we have sow and invested for our health. If you do not want to suffer from dreadful consequences of your own doing then you have to give yourself the protection that you truly deserve.
Grab Some Chromium and fee the difference!
What are Homeopathic Remedies and How do They Work?
March 25, 2011 11:28 AM
Homeopathic remedies have been in use for over a century in treatment of diseases. Homeopathy is considered a forerunner of modern medicine, but today largely classified as a form of alternative medicine. Medications prepared by practitioners of homeopathy are still widely available. Moreover, there has been a resurgence of interest in homeopathy in the past few decades. Germany in particular Grants the title Physician of Homeopathy after a training program of three years while other countries require professional training in more accepted conventional medicine.
Potentization and Succussion
Repertories are the primary source of information for practitioners of homeopathy. These reference books point to a process called potentization, which works on the principle of systematic dilution of substances in a solution. Homeopathic remedies administered today use distilled water or alcohol as major solvents, with proponents of this alternative medicine believing that water has the capability of retaining properties of substances even when the molecules of the substance are no longer present in the solution.
However, this effect is only achieved through succussion, the proper shaking of solution, which must be applied between each process of dilution. On the other hand, desirable dilutions of insoluble solids are possible to achieve by first reducing the size of the substance with the use of a mortar and a pestle. Potentization and succussion produce homeopathic remedies that are believed to display their well-documented potent pharmacological effects.
Law of Similars
Modern scholars consider Samuel Hahnemann to have single-handedly invented the alternative medicine practice of homeopathy. In fact, he coined the term homeopathy and outlined procedures known as homeopathic provings. He was a German physician who studied in several German universities and practiced conventional medicine before he developed the law of similars in response to medical practices of the time that are harmful in general, such as bloodletting. He gave up his medical practice amid the conviction that information on medicine was very limited and often conflicting.
All the homeopathic provings that followed the rise of homeopathy depends on the most important principle he called law of similars, which is believed to govern diseases and their treatment. Substances that produce symptoms similar to a known disease when taken by an individual in large amounts ought to bring about curative effects when taken in small amounts by an individual afflicted with the disease. Homeopathic repertories document the effects of a host of substances and their identified sources in a process called homeopathic proving in an effort to support the laws of similar.
Modern Homeopathic Remedies
The continued support for homeopathy comes from people who are seeking alternative forms of healing. Also, homeopathic remedies that follow standard preparation procedures of potentization and succussion have never been associated with any known adverse effects. While present-day doctors and medical professionals are particularly critical of homeopathic remedies, which they generally consider as placebo, they also believe that homeopathic remedies are the safest among all forms of alternative medicine.
OralBiotic for Ear, Nose, and Throat Health
May 28, 2010 01:29 PM
OralBiotic™ For Ear, Nose & Throat Health
NEW IN JUNE 2010
Many people, even some of the most nutritionally well-versed health enthusiasts, are unaware that the body’s immune system activity actually begins in the mouth. In addition to Amylase, saliva contains an important enzyme, called lysozyme, which functions as a first line of defense against potentially harmful constituents. This simple aspect of human health speaks volumes about what’s happening inside our mouths. The short version is that the mouth offers a near perfect environment for the growth and fortitude of various bacteria; some good, and some clearly not so good. No one is immune to this, including those who are meticulous in their oral care practices.
The food we eat, the environmental particles we inadvertently inhale, and a wide range of additional factors can all contribute to the residual presence of undesirable oral bacteria. For the most part, these particles are harmless and can be washed away by saliva or enzyme activity. Some bacterium, however, can lead to acute halitosis (bad breath) when left behind, as well as a potentially-increased affinity towards various infections resulting from bacterial imbalance. For individuals striving to support on a head-to-toe good health, it is important to take this into consideration when developing or augmenting one’s nutritional program. NOW® Foods new OralBiotic™ is a completely innovative natural supplement developed specifically to help promote healthy oral bacteria, and therefore, a desirable state of overall health and wellness.
OralBiotic™ contains the naturally-occurring probiotic organism Streptococcus salivarius BLIS K12®, which has been shown in clinical studies to support both oral and throat health. OralBiotic™ BLIS K12® is not an antibiotic, but it can successfully colonize the oral cavity at the expense of other bacteria, thereby encouraging oral health.1 For greater support, we’ve included Fructooligosaccharides (FOS), a prebiotic that provides nutritional support for the growth and preservation of S. salivarius. OralBiotic™ can also promote fresh breath when used in conjunction with proper oral hygiene, such as NOW® XyliWhite™ products. To help your customers get the most out of this exciting new formula, we recommend taking it in conjunction with one of
NOW® Foods’ various high-potency natural Probiotic supplements.*
BLIS K12® Advantages:
• The strength of the scientific and clinical data behind BLIS K12®
• A unique probiotic clinically-demonstrated to benefit the mouth and throat*
• Strong IP position (13 patents Granted worldwide and 15 patent applications pending)
• Stability/shelf life (Two years shelf life at ambient temperatures)
• Demonstrated efficacy of various delivery formats
• An extensive safety record and comprehensive safety data
† Used with permission from the BLIS K12® website
June 11, 2009 06:16 PM
The boswellia family of trees are specifically known for their fraGrant, gummy sap, which possesses many medicinal uses. Among these, especially, if the use as an anti-inflammatory. It is believed that the frankincense of the bible was actually an extract from the resin of the Boswellia tree. Boswellia, which is also known as boswellin, has a long history of use in Ayurvedic healing. The resin is called salai guggal and has been used to treat asthma, arthritis, various inflammatory conditions, and to relieve joint pain and pain that results from sports injuries. The resin of the boswellia tree is also though to be helpful for treating back pain as well as some other chronic intestinal disorders.
The boswellia plant is a genus of trees that are known mainly for their fraGrant resin. This resin has many pharmacological uses, particularly as anti-inflammatories. There are four main species of boswellia, producing true frankincense. Each type of resin is available in various grades. These grades depend upon the time of harvesting. The resin of the boswellia plant is hand sorted for quality. Anyone who is interested in frankincense is advised to obtain a small sample from each reputable dealer to determine the difference between each resin.
Boswellic acids are the main compounds that are believed to be at the source of boswellia’s anti-inflammatory properties. These acids have the ability to inhibit the enzymes that induce pain and inflammation in the body.
A few studies have been conducted on boswellia’s effect on sports injuries and arthritis. Among these, some have shown that boswellic acids may contain anti-inflammatory benefits that are extremely powerful. These benefits are similar to those found in ibuprofen and aspirin. One study done on rheumatoid arthritis patients found that pain and swelling were reduced after three months of treatment with boswellia. Those who used boswellia occasionally reported mild gastrointestinal distress, like heartburn and nausea, but there were no other reports of serious side-effects.
Boswellia has a long tradition of safe and effective use as a mild anti-inflammatory to alleviate pain and stiffness. It is also used to enhance mobility without serious side effects. However, further research is needed to confirm the long-term safety and effectiveness of this extract. Boswellia seems to be best taken as needed in order to reduce pain and stiffness, as opposed to being taken regularly as a maintenance herb.
The resin of boswellia is used in many herbal formulas because of its analgesic and anti-inflammatory properties. Primarily, this extract is most useful in dealing with arthritis, asthma, inflammatory conditions, joint pain, and sports injuries.
A boswellia standardized extract is recommended by many doctors. When dealing with rheumatoid arthritis or osteoarthritis, 150 mg of boswellic acids are taken three times per day. For example, if an extract contains 37.5% boswellic acids, 400 mg of the extract would be taken three times daily. Treatment with boswellia should generally last between eight and twelve weeks. Generally, boswellia is safe when used as directed. Rare side effects include diarrhea, skin rash, and nausea. Any inflammatory joint condition should be closely monitored by a health care professional. To date, there are no well-known drug interactions with boswellia.
Boswellia comes in capsule form at your local or internet health food store. When making a purchase always read the label to ensure that the product is standardized to its active acids to ensure quality and purity and to ensure that the herb when taken regularly will function as intended.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Boswellia is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
May 19, 2009 01:10 PM
Even though bayberry is known best for the candle wax that is made from its fraGrant berries, the dried root bark is used very often for its medicinal properties. Bayberry has been long used as a tonic to treat both diarrhea and external wounds. This herb has also been used as stimulant. Some Native American tribes even use bayberry to help reduce fevers. Bayberry is recommended as a tonic for its ability to stimulate the system and increase immune function. It is also recommended as a gargle to help treat tonsillitis and sore throat. It has also been considered that the astringent value of this plant may make it a great candidate for healing wounds.
The root, bark, and leaves of bayberry are used to provide alterative, antibacterial, antiseptic, astringent, emetic, febrifuge, insecticide, sialagogue, and stimulant properties. The primary nutrients found in this herb include calcium, magnesium, manganese, niacin, phosphorus, potassium, silicon, sodium, vitamins B1, B2, C, and zinc. Primarily, bayberry is used for its beneficial effects in treating cholera, colds, congestion, diarrhea, dysentery, fevers, flu, glandular problems, goiters, uterine hemorrhage, indigestion, jaundice, excessive menstruation, and primary tuberculosis. Additionally, this has been shown to be extremely helpful in dealing with bleeding, colitis, bleeding gums, liver disorders, excessive mucus, scurvy, sore and ulcerated throat, thyroid problems, ulcers, prolapsed of the uterus, and varicose veins. For more information of the many beneficial effects of bayberry, please contact a representative from your local health food store.
Bayberry was initially only used in the south of the United States, where the Choctaw Indians boiled the leaves and drank the decoction as a treatment for fever. Later, Louisiana settlers drank bayberry wax in hot water as a treatment for the most violent cases of dysentery. Bayberry was popularized by Samuel A. Thomas, a New England herbalist, in the early 19th century, for its ability to produce “heat” within the body. He recommended this herb be used for colds, flu, and other infectious diseases, in addition to using it for the treatment of diarrhea and fever.
Since then, other herbalists recommend bayberry as it is an excellent emetic after narcotic poisoning of any king. This herb is also valuable when it is taken daily for all kinds of hemorrhages. Bayberry has an excellent general effect on the female organs as it is excellent in helping the uterus during pregnancy. Additionally, it makes a great douche for women. Excellent results have also been demonstrated after bayberry’s use in goiter. Bayberry tea should be used as an enema in treating diarrhea and dysentery.
To treat sores, boils, or carbuncles, the herb should be used as a wash or poultice, or can be applied to the infection as a powder. Bayberry tea is also an excellent wash for both spongy and bleeding gums. When the tea is taken internally, it is useful in jaundice, scrofula, and canker sores in both the throat and mouth. When the tea is taken warm, it promotes perspiration, improves the whole circulation, and tones up tissues. If bayberry is combined with yarrow, catnip, sage, or peppermint, it provides an incomparable remedy for colds.
As you can see bayberry is an herb that is good for many different ailments. Look for this wonderful herb in capsule or tablet forms at your local or internet health food store. Always purchase name brands to ensure quality and purity of the product you purchase.
December 20, 2008 11:16 AM
If starting your day with a cup or coffee or two, having another while you’re on the road, another after arriving at work, and another to get through the afternoon slump, and perhaps a can of pop or a candy bar after work followed by an ice tea and ice cream after dinner, you may have a serious caffeine addiction.
Many people often feel irritable as the next day’s events are closing in on them at bed time and are restless about the next day’s problems race through their mind. It’s been like this for years for many of us, with an estimated 80 percent of adult Americans being regular coffee drinkers and each adult coffee drinker averaging 3.3 cups of coffee per day, without taking into account other sources of caffeine.
Caffeine can be found in tea, chocolate, soft drinks, and medicines, but is most often consumed in coffee. Coffee is somewhat popular because of the stimulating effect of its caffeine constituent, but it can contribute to irritability, depression, diarrhea, insomnia, and other disorders. The number one legal mind-altering drug in the world, caffeine is odorless, slightly bitter and can be found in coffee, tea, kola nuts, ilex plants, mate, and cocoa. You may know and accept that you have a caffeine habit, but many people are convinced that they need a pick-me-up from time to time in order to get through the day. What is important is that caffeine is not actually giving you the burst of energy, but instead negative moods and emotions.
The coffee tree, which is a small evergreen, has smooth leaves and clusters of fraGrant white flowers that mature into red fruits that are about half of an inch long. The fruit contains two seeds usually, which become raw coffee beans when dried. After roasting, coffee contains more than 700 volatile substances including acids, alcohols, and even residues of cancer-causing pesticides. In all fairness, caffeine does act as a mild stimulant to the nervous system when used in moderation, which results in a feeling of well-being and alertness. It increases the heart rate, urination, and stimulates the secretion of stomach acid.
Although a little caffeine may wake us up and give us a sense of energy, too much caffeine actually hurts our moods and overall well being. Two cups of caffeine per day seems to have a positive effect, but research shows that even one cup a day is enough to cause dependence. Caffeine may temporarily improve your mood and give a sense of vitality, it wears off and your mood and energy levels crash to levels even lower than before. Additionally, our bodies adjust, causing us to need more caffeine to give us the same desired effect. Caffeine does not provide any energy or increase our alertness. Instead, it stimulates our bodies.
Excessive intake of coffee can lead to restlessness, insomnia, and heart irregularities. Those people who drink a lot of coffee often complain of jittery nerves, chronic anxiety, frequent bouts of diarrhea or loose stools, and restless nights. Coffee can also cause stomach and intestinal problems, as well as coronary diseases. An occasional cup of coffee is one thing, but depending on a cup to keep you awake is something entirely different.
Harsh symptoms of withdrawal such as headache, fatigue, and depression are common among regular caffeine users. Caffeine also causes the body to expel vital nutrients like b vitamins from the body that we need to function. If you consume more than two cups of coffee each day then a multi-vitamin should be taken once daily to help replenish was is lost by the diuretic effects of caffeine in the body.
December 10, 2008 10:48 AM
Hoodia Gordonii is a South African succulent plant of the family Apocynaceae. They are remarkable similar in appearance to cacti, although they are totally unrelated to them and grow predominantly in the region of Central Namibia in the south west of Africa, up to the southern regions of Angola. They are most commonly found in rocky ground and on the plains.
There are several species of hoodia, some of them grown domestically, and it is Hoodia gordonii that is used as an appetite suppressant in hoodia weight loss pills. Although the plant has historically found use in the treatment of infections and gastric problems, most interest is displayed in its use by the bushmen of the Kalahari Desert to suppress their appetite during long hunting trips when food and water are scarce.
The active ingredient was isolated in 1977, and given the name P57: the product is therefore often referred to as Hoodia P57. It was patented by its discoverers, the CSIR (South African Council for Scientific and Industrial Research) and a license Granted to UK company Phytopram, who worked together with Pfizer to isolate the active ingredients and manufacture them synthetically. This was found to be very difficult, if not impossible, since any synthetic form of the extract failed to display any hunger-suppressant properties.
Finally, the rights to the main ingredient were released by Pfizer in 2002, thus indicating that it was of no commercial benefit to them. The main problem they admitted with synthesizing P57 was not only the difficulty in doing so, but also that there were side effects of the extract on the liver caused by other components that could not be removed. No synthetic form of hoodia is therefore available, and only the natural plant is used in current Hoodia 57 preparations.
The rights of the San Bushmen to the plant were recognized by the CSIR in 2002, and not only do they receive a proportion of the profits of marketing hoodia, but also the plant is protected with wild-harvesting licenses provided to only certain individuals and companies. Due to the rising popularity of the hoodia weight loss industry, the plant has been named as an endangered species in the wild.
It is believed that the active ingredients are steroidal saponins that can fool the body into believing it is full. This theory is based upon the effect on appetite of glucose concentrations in the blood. Your appetite is controlled by the amount of unconverted glucose in your blood, and glycogen in the liver. When you eat carbohydrates, they are digested and converted into glucose which is absorbed into the bloodstream.
Under normal conditions your blood glucose levels increase to a level where a signal from hypothalamus stops you feeling hungry. Insulin is then secreted from the pancreas to prepare your cells to use that glucose in the mitochondria to create energy by means of the Kreb's Cycle, or Citric Acid Cycle as it is also known. This reduces the concentration of glucose in the blood, and once it reaches a certain level the body begins to use its emergency energy supply, glycogen, that is stored in the liver.
A signal then informs the brain that more glucose is needed. You then feel hungry again, and this cycle is repeated several times a day in a normally healthy person. This cycle is controlled by certain hormones in the brain, specifically in the ventromedial center of the hypothalamus, where it is believed that the ATP (adenosine triphosphate) availability controls the release of the hormones involved.
ATP is the molecule of energy, and as the concentration of blood glucose and of glycogen drop, then the amount of ATP produced also drops and this is detected in the hypothalamus, which reacts by releasing ghrelin. Increased leptin increases the feeling of satiety and ghrelin increases the feeling of hunger. Serotonin acts on the brain to increase the effect of leptin in the hypothalamus, and therefore make us feel less hungry, or more satiated.
It is believed that hoodia gordonii, or the Hoodia P57 component of it, fools the brain into believing that your blood glucose or glycogen levels have reached the point at which it should trigger a satiated response, so that you stop eating even though your ATP levels might be low. The steroidal saponins that it contains is believed to be ten thousand times more effective than glucose in stimulated the secretion of serotonin.
Hoodia has also been found to contain a number of glycosides, including pregnane glycosides that some studies have indicated to help control appetite of the subjects tested. Most of these tests have been carried out on animals, although Hoodia weight loss preparations are offered in a form standardized on both steroidal saponins and pregnane glycosides.
Hoodia gordonii is becoming so popular as a weight loss product that its export is being monitored by the South African government. It has become so endangered that, since 2005, only hoodia grown on commercial farms is permitted an export license, and exporters must obtain a license from the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). Importers also require a permit from the US department of Agriculture, and a CITES certificate is also needed to re-export the finished product.
Because of this, more hoodia weight loss pills are being sold than there is hoodia gordonii to produce them. It is not uncommon for cacti such as the prickly pear cactus from Mexico, to be used, or for low concentrations of hoodia to be bulked up with fillers. Neither of these is of any use as an appetite suppressant, the former having no active ingredients whatsoever and the latter containing only traces.
If you are purchasing hoodia, therefore, be aware of this. Request sight of the CITES certificate and USDA permit, and also the analysis results by an authorized laboratory to confirm that the product is what it purports to be. Otherwise, there is some evidence that Hoodia gordonii can help you reduce weight, although to date there are only four recognized analytical laboratories registered to analyze the active content of hoodia weight loss products.
Finally, check for the analysis certificates. All Hoodia weight loss products should be analyzed by each of three methods: Microscopy, High Performance Thin Layer Chromatography (HPTLC) and High Performance Liquid Chromatography (HPLC) - all there are needed. The four authorized laboratories are: the University of Mississippi, Chromadex labs in Irvine California, Alkemist Pharmaceuticals and Advanced Laboratories, Smithfield, NC.
No others will do, so if your Hoodia weight loss preparation has not been analyzed using the three methods by one of these laboratories, don't buy it, even if it can show the CITES and USDA documentation.
NK Immune Boost
September 25, 2008 03:59 PM
The immune system is the ultimate bodyguard that can prevent illnesses before it even takes hold in the body when it is properly taken care of. Immune impairment has become a major concern within recent decades among health professionals. The strength of the immune system directly influences the quality of health. However, it is often something that we take for Granted. There are a lot of things that can interfere with proper immune function, including diet, stress, and level of activity. It is within our ability to create a health immune system for ourselves.
If we do something that makes us a little bit healthier, we will experience less disease and suffering. Each of us individually must do what is necessary to protect ourselves from common health threats that can occur if the immune system is compromised like heart disease, arthritis, fibromyalgia, gastrointestinal problems, AIDS, cancer, and many other illnesses. We will be able to avoid disease and the suffering it causes if we do what is necessary to keep our immune system healthy and balanced.
In order to understand how to fight against health problems in the best way, it is necessary to first understand the basics of how the immune system functions. The smallest components of the immune system are biomolecules, which are also called immune factors or immuno-regulatory molecules. The immune system fights against the potential health dangers by identifying and then eliminating dangerous and unfamiliar particles, which include bacteria and viruses. The immune system can very selectively discriminate between self and non-self, a trait that is extremely unique. It then destroys the foreign antigens and leaves itself alone.
Biomolecules called cytokines work to regulate and simulate the body’s defense system. Cytokines help to fight against foreign molecules, also called pathogens, by inducing the production of antibodies. These antibodies work to neutralize antigens and create immunity to them. Additionally, a functioning immune system remembers the foreign antigens that it has encountered before so that it can prevent or quickly defeat secondary attacks by the same pathogen.
There are many immunity agents that are found in the body. An antibody is a molecule of the immune system that is secreted into the blood and helps to fight against antigens like bacteria and parasites to help create immunity, Antigen are substances that stimulate the production of an antibody when it is introduced into the body. Antigens include toxins, bacteria, foreign blood cells, and the cells that are found in transplanted organs. Colostrum, antibody-rich milk, is produced by a mother during the first week of her child’s life. Cytokines consist of any of several regulatory molecules that are released by cells of the immune system and acts as a mediator in the generation of an immune response. Cytokines assist in the regulating and controlling of the immune system.
Interleukin is a type of cytokine which encourages the growth of immune cells. There are many types of interleukins, with three of the most common stimulating the inflammatory response, the growth of blood stem cells, and the production of helper T cells. Pathogens are agents that cause disease, while tumor necrosis factor is a type of cytokine that has anti-tumor properties. It affects blood vessels, therefore, regulating both inflammation and killing tumors. Lastly, white blood cells help to protect the body from infection and disease.
Keeping the immune system in tip top shape is very important. There are a variety of natural substances such as colostrum that can help the immune system function at optimal levels. Natural supplements are available at your local or internet health food store.
Evening Primrose Oil
September 04, 2008 09:08 AM
The tiny seeds of the evening primrose flower are the source of oil that has been valued in the world for building health and overcoming a lot of common health problems. Evening primrose, also known as evening star, night willow herb, scabish, and tree primrose, has a recorded history of at least 500 years of use for its health promoting properties. Growing in a wider variety of climates, the plant can be found in rocky roadsides, shallow streams, or even high deserts.
The plant can even be found growing at elevations as high as 9,000 feet. This plant has yellow flowers from July through September that open after sunset and are pollinated by insects of the night. Open only until sunrise, the flowers die the next day, causing hundreds of small black seeds to form inside. These seeds are the source of the plant’s oil, with about 5,000 seeds being used for just one 500 mg capsule. Due to this, evening primrose can be relatively expensive. Evening primrose’s value in a variety of illnesses was recognized by American Indians and European immiGrants. Indians used it to treat skin wounds, asthma, coughs, and also as a sedative. One of the first botanicals exported to Europe from North America, it was brought to Italy in 1619 and planted in the Padua Botanical Gardens. It was so valued by the Puritans that they called it the “King’s cure-all” and exported it to England. The ancients didn’t know scientifically why evening primrose was so effective for so many illnesses, but that didn’t affect its abilities. Modern science has found that the essential fatty acids that are found in the oil of the evening primrose seeds are the secret to the health-building properties.
Fat has gotten a bad name for itself in the past few years, but the truth is that there are actually certain types of fats that are vital for good health. One of these healthy fats is essential fatty acids, which are found in unprocessed vegetable, plant, and fish oils. One of the richest sources known is actually mother’s milk. Like vitamins and minerals, essential fatty acids are nutritional substances that have far-reaching effects on many body processes.
These effects include reducing blood pressure, helping to prevent arthritis, reducing the growth rate of breast cancer, lowering cholesterol and triglyceride levels, maintaining healthy skin, aiding in transmission of nerve impulses, playing a role in normal brain function, constituting the building blocks of body membranes, promoting proper hormone function, and forming the basis for prostaglandin production.
Because essential fatty acids can not be manufactured in the body, they must be consumed in the diet, with at least three percent of an adult’s daily caloric intake being recommended to be comprised of essential fatty acids. Children and pregnant women should have a diet containing at least five percent essential fatty acids. Essential fatty acids are essential for normal functioning of all body tissues.
Because of this, the list of symptoms of essential fatty acid deficiency includes reduced growth rate, skin disorders, male and female infertility, kidney abnormalities, decreased capillary resistance, susceptibility to infection, heart problems, anemia, enlarged liver, sparse hair growth in infants, poor wound healing, and an increased susceptibility to infection.
In conclusion, to prevent or heal these conditions, a diet that is rich in essential fatty acids must be present. Evening primrose oil is a good source of essential fatty acids, containing about 72 percent linoleic acid and 9 percent GLA. Have you had your evening primrose oil today?
Pinolenic Acid - Appetite Control
April 25, 2008 02:50 PM
Mention "pine nuts" and peoples’ mouths are apt to start watering for a taste of garlicky pesto or fraGrant pilaf. Ironically, the same ingredient that is so irresistible in gourmet cooking may help curb our out-of-control appetites. But only a particular variety of pine nut—Pinus koraiensis from Korea—will do.
Source Naturals PineSlim is a Korean pine nut oil (PinnoThin™). A small-scale study suggests that PineSlim may reduce feelings of hunger by increasing concentrations of appetite-suppressing hormones. The study also suggests that a feeling of fullness is experienced 30-60 minutes after taking PineSlim. For best results, PineSlim should be taken while following the Maximum Metabolism Weight Loss Plan™ enclosed in every bottle.
Enjoying good food is part of a healthy lifestyle, but too often we don’t know when to stop. PineSlim can help by addressing one of the most basic of the dozen deep metabolic systems identified by Source Naturals as critical to your optimal health: Hormones/Metabolism.
Less Calories for Improved Health
According to a National Health and Nutrition Examination Survey, an estimated 66% of U.S. adults are overweight. A normal body fat level is one of the factors associated with many markers of good health, including insulin efficiency, healthy inflammation response, good circulation, and normal cell regeneration. One of the best ways to achieve healthy weight is by curbing the amount of calories we take in—but that’s not always easy to do. Now an ancient Asian food source may help.
Korean Pine Nuts—Traditional Asian Food
The Korean pine nut (Pinus koraiensis) has been used as a food source for centuries and is often served as a snack at social events in China. Korean pine nuts grow on evergreen trees that produce seeds (commonly referred to as nuts) that are rich in oil, particularly oleic, linoleic, and pinolenic acids.
Pinolenic acid is a fatty acid, which may influence healthy blood pressure. According to recent research, pinolenic acid also may increase concentrations of the satiety hormones glucogon-like peptide-1 (GLP- 1) and cholecystokinin (CCK).
Both GLP-1 and CCK are hormones that have been found to increase satiety and suppress appetite in normal-weight humans. They are believed to work by delaying gastric emptying. Retaining food in the stomach for a longer period of time may prolong a feeling of fullness.
In a randomized, double-blind trial, 18 overweight women received 3.00 grams of Korean pine nut oil (PinnoThin™)—the same amount as one daily dose of Pine Slim—or an olive oil placebo before a carbohydrate meal. Hormone measures of CCK and GLP-1 were taken from blood samples, and subjective measures of appetite were recorded. The study demonstrated a significant increase in appetite-suppressing CCK and GLP-1 hormones at 30-60 minutes after supplementation.
Your Source for Advanced Nutrition
The plant world offers an abundance of health promoting compounds. Today exciting discoveries are emerging from research into the health benefits of botanicals. The development of PineSlim reflects Source Naturals’ commitment to manufacturing supplements on the cutting edge of nutritional science. We are glad to partner with your local health food store in bringing you nutritional resources that help you take charge of your health.
Causey JL (3/28/06) Korean Pine Nut Fatty Acids Induce Satiety-producing Hormone Release in Overweight Human Volunteers, American Chemical Society Abstract, “Health Benefits of Lipids” Symposium. ABSTRACT 0117: TECH-3.
Fontana L. (2006) Excessive Adiposity, Calorie Restriction, and Aging. JAMA. 295(13): 1577-1578. Masoro EJ. (2005) Overview of caloric restriction and ageing. Mech Ageing Dev. 126: 913-922. Sugano M, Ikeda I, Wakamatse K, Oka T. (1994)
Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. British Journal of Nutrition. 72:775-783.
Secondly, the Herb Boswellia
April 03, 2008 12:43 PM
Boswellia is a tree that has a number of different species that have been used in Ayurvedic medicine. This is a form of Indian medicine that is used today by millions in India, and also in the neighboring Nepal and Sri Lanka. Its approximate translation is ‘Meaning of Life’, or could even be subtended to ‘Science of Life’, and is more a system of health care than the treatment of specific conditions.
There are four species of Boswellia: Boswellia carteri, Boswellia frereana, Boswellia sacra and Boswellia serrata, and it is B.serrata that is predominantly used in Ayurvedic medicine to treat a number of conditions, including ulcers, rheumatoid arthritis, dysentery and asthma. It is not coincidence that most of these are inflammatory conditions, and even dysentery is a form of inflammatory colitis.
You might be more familiar with Boswellia by the fraGrant resin that it produces: Frankincense. There are different grades of Frankincense according to the species and grade of Boswellia, and if you are using the resin for its aroma then that could be an important consideration. However, the active ingredient of Boswellia are the so called boswellic acids that are contained within the resin.
It has been used in the treatment of a number of inflammatory conditions including asthma. Many do not realize that asthma is an inflammatory response of the immune system to particulate irritants in the airway such as cigarette smoke and other small particles. In this case the inflammation is caused by the histamine that is released by mast cells sent to the area of irritation by the immune system.
Artichoke Promotes Healthy Fat Digestion and Metabolism
January 30, 2008 10:37 PM
In discussing the health benefits of the artichoke, and the way it promotes healthy fat digestion and metabolism, we are talking here about the true artichoke: the globe artichoke. The alternative Jerusalem artichoke is not an artichoke at all, but a member of the sunflower family. The globe artichoke is a type of thistle.
It is in fact a perennial thistle that originated in the Mediterranean area and is now cultivated world wide. The edible portions are the lower parts of the bracts and the base of the buds, known as the heart while the inedible portion in the center of the bud is known as the ‘choke’. Globe artichokes were introduced to the USA in the 19th century by French and Spanish immiGrants who settled in Louisiana and California respectively. Contrary to popular opinion its name did not come from the ‘heart’ and the ‘choke’, but from the Arabic for ground thorn: ‘ardi shauki’.
In today’s world of fast foods, a high consumption of fats and red meat and excessive alcohol consumption, your liver is put under a great strain. Its main function is as a chemical factory, to produce the chemicals, such as enzymes and other proteins, needed to maintain life and also to metabolise the nutrients we need from the food we eat. If you overtax your liver it will not work as it should, which results in poor digestion and assimilation of the nutrients in your food and an increase in the toxins in your blood.
You will feel tired and run down, with digestion problems and many other health complaints. Liver abuse can result in malnutrition, which also results in cirrhosis which is not curable. You should seriously appraise your diet, and identify the eating and drinking habits that are causing the problem, and give your liver a rest. Artichoke extract is a great liver tonic, and your liver will respond well to a break from alcohol and fatty foods, and a course of artichoke leaves and extract.
The main active ingredient of the artichoke is cynarine (1,5-dicaffeylquinic acid), a substance that stimulates the production of bile, and hence renders the artichoke an excellent starter for any meal. This is yet another example of science finding a logical reason for people eating artichokes for centuries in order to promote the health of their liver and digestive system. It is not only for its cynarine content that the globe artichoke is useful, however, but also the luteolin and chlorogenic acids that it contains.
The stimulation of bile production by the cynarine is one the more important of the effects of artichoke on your well being. Bile emulsifies fats and renders them into an easily digested form. Most of the digestive chemicals are water soluble, and without this emulsification of the fat with water then most of the fats we consume would pass through the body unchanged. We would the vats majority of the fat soluble nutrients in our food, including vitamins A, D, E and K.
Bile enables us to digest fats and to absorb vitamins from our food, and also promotes the general health of our digestive system. It is biosynthesized in the liver from various enzymes and triglycerides and then stored in the gall bladder until needed. Its use is prompted by the presence of fats in the system, and this is stimulated by the cynarine in the artichoke leaves.
Its ability to improve bile flow has been recognized by scientist’s world wide, and artichoke juice has been used by the French for many years as a liver tonic. However, it is not just for the liver and the digestive system that artichokes are useful in maintaining good health. They also have an effect on the cholesterol levels in your blood. This is believed to be due to the inhibition of the activity of enzyme HMG CoA Reductase that helps the liver to generate cholesterol. Inhibiting the activity of this enzyme reduces the amount of cholesterol produced.
This can have the effect of reduced the possibility of you developing atherosclerosis, a condition caused by deposition of low density lipid (LDL) cholesterol through the effect of free radical oxidation of the lipid. The less cholesterol to be transported by your blood, then the lower levels of the low density lipid needed to do this. This effect is also possibly due to the fact that bile is formed from cholesterol and triglycerides, and so stimulated bile production would possibly leave less cholesterol in the bloodstream.
Artichoke also possesses antioxidant properties that would contribute even further to this effect by preventing the oxidation of the LDL by free radicals. These free radicals, formed in the body both naturally and by the effects of pollutants such as pesticides, cigarette smoke and traffic fumes, are destroyed by antioxidants. In atherosclerosis the LDL lipids are oxidised and deposited under the surface cells of the blood vessels, and are then digested by certain blood cells forming a hard fatty deposit that can eventually block the arteries affected.
The result can be a heart attack or a stroke, depending on where in the body the blood vessels are affected, and if the cholesterol levels in the body are decreased through it being used to produce bile, then the concentration of LDL lipids used to transport it will also be reduced and the condition will be less likely to occur..
Apart from the liver, the gall bladder is also given a boost by artichoke because that is where bile is stored, and a regular flow to and from the gall bladder maintains its health. The only thing you should be aware of if is that if you are prone to gallstones then the increase in bile flow could cause the stones to be stuck in the bile duct. You should therefore refer to your physician before embarking on a course of artichoke extract if you have a propensity to develop gallstones.
Apart from the phytonutrients already discussed, the globe artichoke also contains a good supply of fiber and minerals such as potassium, iron, calcium and phosphorus, and also some trace elements that your body needs. It is therefore more than just a bile stimulant, but provides a wide range off essential nutrition to your body. It is know to aid conditions such as gout, high blood sugar, and digestive complaints such as flatulence, bloating and abdominal cramps.
Apart from cooking and eating the tender parts of the leaves, or bracts, you can make an infusion of the parts that you don’t eat. Chop up the tougher leaves and pour boiling water over them as if making tea. Leave it to infuse for a few minutes and then drink. Honey can be used to take away the bitter taste; honey rather than sugar due to its greater nutritional content.
The Growing Organic Market Place
June 26, 2007 01:51 PM
It probably doesn’t come as much of a shock that the market for organic produce is growing—estimated by various sources at about 20 percent a year. What may be surprising is that the organic food market, which generated about $13.8 billion last year, represents only about 2.5 percent of the total U.S. food consumption.
While those of us involved in the natural products industry or natural healthcare take for Granted the advantages of organic products over “traditional” ones, there is a pressing need to mobilize resources in order to meet the consumer demand for pesticide-free foods.
Currently, only 0.2 percent of the U.S. farmland is organic. The other 99.8 percent produces food utilizing the high-production, low-nutrient and flavor lacking industrial chemical methods we grew up with—the same tradition that drove consumers to seek out organic produce in the first place. The picture isn’t any better in Canada, according to the Canadian Organic Growers Association, where only 1 percent of the food grown there is organic.
This of course raises the question as to how we are going to satisfy this increasing consumer demand. In a word: imports. We already import more than 10 percent of the organic food we eat. But perhaps the figure of greater interest is that we consume 42 percent of the worldwide organic food supply, leaving only 58% for world’s non-U.S. residents.
In this enlightened era in which we understand the downside of processed foods, chemical residue and the portent of global warming, it’s hard to understand why we don’t muster our great resources and legendary spirit to launch a program to address these issues—like JFK’s Apollo Project, which put a man on the moon in under a decade using computers less powerful than are commonly found on our desktops today.
While we ponder the question, there are people of good will and strong conviction who are working, albeit with limited resources, to do something about it. one group is working on remineralizing the earth. We are proud to be supporters and friends and we think you will find their concept as exciting as we do. -Peter Gillham – editor.
May 20, 2006 12:15 PM
Today’s scientists might be less poetic that tea’s ancient admirers. But they are no less impressed by the fraGrant beverage’s lengthy list of health-boosting compounds, including a powerful antioxidant called epigallocatechin gallate (EGCG) that may interfere with potentially harmful genetic changes. Researchers at the University of Rochester (New York) Medical Center have found that EGCG binds to a protein called HSP90, jamming an important gene-damaging mechanism (biochemistry 4/5/05). Tea may also help stymie cancer development by interacting with toxin-neutralizing enzymes in the liver and by encouraging apoptosis, a process that causes cells to die when their useful life is over.
Studies of actual tea-drinking humans have had mixed results; some show a cancer-preventive effect, others don’t. The most promising research comes from China, where green tea is the beverage of choice. Among more than 18,000 men, those who drank tea were half as likely to develop cancer of the stomach or esophagus (which leads from the mouth to the stomach) as non-imbibers (Carcinogenesis 9/02).
Americans have traditionally favored black tea, which has different chemical properties. A 2005 American Institute for Cancer Research survey showed that only 15% of the US population drinks green tea on any given day and less than 1% matches the per-person consumption seen in Asia (although green tea sales have climbed considerably in recent years).
Meanwhile, the good news continues to pour in. in February, an investigation published in the Journal Carcinogenesis found a 22% drop in breast cancer risk among women who quaffed five cups a day. And in two preliminary studies, green tea extract, which provides tea compounds in an easy-to-take, form, has been linked to reduced risk of cancer in men with precancerous prostate changes and has benefited people with leukemia.
At Last some good news concerning breast health!
February 23, 2006 03:33 PM
At last, some good news concerning breast health!
Brevail is for women interested in maintaining optimal breast health.
Perhaps you, like many woman, are concerned with the important issue of breast health. Annual mammograms, monthly self breast exams, escalating national statistics, or perhaps an unfortunate occurence in a loved one has raised awareness and concern in many of us.
There is now reason for Optimism
Brevail is the first all-natural product to address the maintenance of orderly cellular division in the preservation of healthy breast tissue.
Research suggests that our bodies use natural plant lignans, now sparse in the modern diet, to sarely and gently buffer and balance potentially adverse effects of excess or toxic estrogens, established as the most well-known cause of certain breast problems.
Estrogen left unchecked may result in rapid multiplication of breast cells, as well as inability for cells to repair potential mutations between cellular divisions.
Body and Nature is balance
Brevail was university researched and developed to increase lignan concentrations in the body to levels found in women who collectively demonstrate an extraordinary history of breast health.
After only 48 hours of Brevail supplementation, women participating in a university based, oral pharmacokinetics study achieved lignan concentrations in plasma and urine equivalent to a reference group of women with a well-established history of extraordinary breast health.
The results is a gentle return to balance between body and nature, just as nature intended.
In addition to the primary purpose of optimal breast health, many women have reported secondary benefits of brevail related to hormonal balance including improvements in pre and peri-menopausal, menopausal and post-menopausal discomforts. Further, many women have reported a greater sense of well-being associated to a reduction of stress and apprehension, and for taking a positive step toward a healthy future.
Brevail has good news for you, a “window” of opportunity.
The good news is a revolutionary new approach to breast health. Though a new approach, managing your “Estrogen window” is time honored, true, and scientifically established.
Your lifetime exposure to estrogen is the most well-known risk factor for breast related health challenges. Your cumulative lifetime exposure to estrogens is referred to as your “Estrogen window.” Influences that increase and extend exposure to estrogen are said to “open” the window. Those that reduce or shorten exposure are said to “Close “ it. The wider and longer the window is left open, the greater your risk for breast related complications.
Managing your estrogen window empowers you to choose a healthy future.
Brevail is the first all-natural product designed to address the estrogen window by gently displacing excess or toxic estrogens. Adequate rest, exercise, a plant-based diet, and avoidance of alcohol are also ways to which you can consciously choose to manage your estrogen window toward a healthy future.
Make a decision for health, life, and vitality!
Proactive Breast Health is a monumental shift in thinking and action, away for passive resignation and toward proactive empowerment. The difference between fate and destiny is that you can plan your destiny in advance. Make a commintment to Brevail, and make a commitment to health, life, and vitality today.
Brevail donates a percentage of all proceeds to the Breast Cancer Prevention Foundation, established to fund scientific and clinical research into breast cancer prevention, as well as to educate the public and medical community on proactive and preventative breast health measures, and for the purpose of outreach and support for women with breast cancer.
Brevail, winner of two consecutive research Grants
Brevail was awarded an unprecedented two consecutive research Grants from the Washington Technology Center, University of Washington, in the course of the 6-year span in which it was developed. Lignan Based strategies for Cancer Prevention was the topic and title of the Grants.
December 22, 2005 09:37 AM
Glucosamine & Chondroitin - JOINT HEALTH
Everyone old enough to walk appreciates the value of fl exibility and ease of movement. Unfortunately many of us take such good things for Granted. A famous folksinger sang, “You don’t know what you’ve got till it’s gone.” That’s certainly true for millions of Americans who live with stiff and uncomfortable joints.
Fortunately there are a number of nutrients available that provide the vital components of healthy joint structure and function and ease of mobility. These nutrients are referred to as “chondroprotective agents,” and include glucosamine and chondroitin, which supply the raw material necessary to produce new cartilage, and may even help rebuild worn cartilage. Other chondroprotective nutrients and herbs, like Cetyl Myristoleate, MSM, and Boswellin, work synergistically with glucosamine and chondroitin and further support normal joint function To understand how chondroprotective agents work, one must fi rst understand how joints work. The key element in human joints is articular cartilage, the shock-absorbing tissue that connects two bones together and allows pain-free movement. Articular cartilage is comprised of two different molecules, collagen and proteoglycans, with the remainder composed primarily of water (65-85%). Collagen, a protein that binds tissue together, provides elasticity. Proteoglycans, composed of sugars and protein, absorb water, which provides lubrication and resiliency, nature’s shock absorber for your joints. Both compounds are produced by chondrocytes, caretaker cells responsible for the formation and maintenance of cartilage. A defi ciency in any one of the above constituents will increase the likelihood of wear and tear on articular cartilage, which can eventually lead to compromised joint function.
Glucosamine and chondroitin are safe, natural and effective nutrients that support healthy joint function by supplying the materials needed to produce collagen and proteoglycans.
Glucosamine is composed of glucose (a sugar) and glutamine (an amino acid). It is utilized by chondrocytes to form glycosaminoglycans (GSG) and proteoglycans (PG). Both of these constituents attract and bind water into cartilage, increasing resiliency. Research indicates that glucosamine may actually help your body repair damaged or eroded cartilage. A number of studies have been conducted on glucosamine sulfate and glucosamine hydrochloride, with a preponderance of positive results. Glucosamine sulfate is considered the more effective of the two. One study from the University of Liege in Liege, Belgium studied the effects of glucosamine sulfate on 212 patients with knee osteoarthritis. Participants took either 1,500 mg glucosamine or a placebo once daily for three years. The study compared joint-space width at enrollment, one year, and at the study’s conclusion.
The 106 patients on placebo had a progressive jointspace narrowing, while participants taking glucosamine experienced no significant joint-space loss, indicating glucosamine may benefi cially modify cartilage structure.3 A study published in the journal Osteoarthritis and Cartilage in 1998 investigated the in vitro effects of glucosamine sulfate on proteoglycan and collagen production by chondrocytes taken from osteoarthritic articular cartilage. The results showed “a statistically signifi cant stimulation of PG production by chondrocytes from human osteoarthritic cartilage cultured for up to 12 days in 3-dimensional cultures.” 4 Another study from Italy enrolled eighty inpatients with established OA. They received either 1,500 mg of glucosamine sulfate or placebo daily for 30 days. The patients treated with glucosamine sulfate experienced a reduction in symptoms almost twice as large and twice as fast as those receiving placebo. Researchers also used electron microscopy of patient’s articular cartilage to support this hypothesis. Patients who received glucosamine sulfate showed a picture more similar to healthy cartilage. The researchers concluded that glucosamine sulfate tends to rebuild damaged articular cartilage and restore articular function.5
Chondroitin is classifi ed as a glycosaminoglycan. It bonds with collagen to form the basis of connective tissue. Chondroitin helps attract fl uid into proteoglycans, thereby bringing nutrients into cartilage and providing shock absorption. While glucosamine helps manufacture and maintain cartilage, chondroitin keeps cartilage from becoming malnourished. Chondroitin works synergistically with glucosamine, and these two nutrients form the basis of most joint health supplements on the market today. A 6-month randomized, multi-center, double-blind, doubledummy study published in 1996 compared the effectiveness of chondroitin versus a popular non-steroidal anti-infl ammatory drug (NSAID) in patients with knee osteoarthritis (OA). One hundred and forty-six patients with knee OA were recruited and separated into two groups; an NSAID group and a chondroitin sulfate (CS) group. The NSAID group was given the NSAID and a placebo for the fi rst month, then placebo alone for months 2-3. The CS group was given the NSAID and CS for the fi rst month, and then CS alone for months 2-3. Both groups were then given 1200mg of CS for months 4-6. “Patients treated with the NSAID showed prompt and plain reduction of clinical symptoms, which, however, reappeared after the end of treatment; in the CS group, the therapeutic response appeared later in time but lasted for up to 3 months after the end of treatment. CS seems to have slow but gradually increasing clinical activity in OA; these benefi ts last for a long period after the end of treatment.”6
NOW® Foods is your source for natural joint support products. Our Extra Strength Glucosamine & Chondroitin is one of our best-selling products, and we also have combination supplements that include MSM, Concentrace® minerals, and more. We also carry both glucosamine and chondroitin as separate products, as well as in powder and lotion forms.
December 17, 2005 09:42 AM
Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood
As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body.
There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable.
Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel.
SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.*
SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance.
As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants.
Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health.
SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification.
SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were Granted to allow the production of SAMe in a stabilized form.
SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability.
This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed
Coenzyme Q10 and Cardiovascular Health.
December 13, 2005 11:34 AM
CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function!
CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body.
CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits.
As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, Granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.”
“The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication.
Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.
Court Rules for FDA in Lane Labs Appeal
December 12, 2005 09:44 AM
A federal appeals court has ruled that Lane Labs (Allendale,NJ) may be ordered to pay back consumers for selling what the food and drug administration (FDA) considered unapproved new drugs. The three-judge panel upheld the 2004 decision by U.S. district Judge William G. Bassler of the District of New Jersey, which stated that FDA may demand that Lane Labs pay back every consumer who had bought the company’s top selling products—shark cartilage supplements that were allegedly marketed as treatments for diseases including cancer and HIV. The restitution amount is estimated at 109 million. The appeals court rejected the argument that FDA cannot demand restrictions because the Federal Food, Drug, & Cosmetic Act (FDCA) does not expressly provide for such a remedy. “Whether or not congress specifically contemplated restitution under the FDCA, the ability to order this remedy is within the broad equitable power Granted to the district courts to further the economic protection purposes of the statute,” 3rd Circuit Judge Marjorie O. Rendell wrote in an opinion joined by Judges Maryanne Trump Barry and Edward R. Becker.
In its appeal, Lane Labs was supported by an amicus brief from the Washington Legal Foundation (WLF, Washington, DC) urging the court to reverse Bassler’s decision, on the grounds that restitution is not authorized anywhere in the text of the FDCA.
WLF attorneys Daniel J. Popeo and Richard A. Samp, joined by attorney Jeffrey A Lamken of Baker Botts in Washington, DC, argued that the FDCA gives courts the power to “restrain” violations, but does not allow FDA to seek “Backward-looking monetary relief.”
WLF argued that FDA, throughout most of its history, never asserted a right to seek restitution until recently, when it began asserting that power in order to have “a big club with which to intimidate manufacturers who might otherwise seek to challenge FDA directives,” including large pharmaceutical companies. However, the court upheld FDA’s authority to seek restitution on the grounds that the FDCA’s Grant of authority to restrain violations of the Act should be read broadly to include all forms of equitable relief.
FDA cannot be allowed to get away with this power grab,” said Samp after reviewing the Third Circuit’s decision. “The American economy suffers, and public safety and health are jeopardized, when FDA seeks to exert power beyond its authority, upsetting to delicate balance struck by Congress in its attempt to both preserve the public welfare and encourage valuable pharmaceutical innovations.” He added that WLF has pledged to continue to litigate the issue and to support Lane Labs in any further appeals the company may file.
CLA Extreme Fact Sheet
December 07, 2005 12:59 PM
CLA Extreme Fact Sheet Neil E. Levin, CCN, DANLA 01/31/05
LIKELY USERS: People wanting to control body fat; People wanting to increase their body’s lean mass (muscle tissue); People wanting an oil that helps to reduce pro-inflammatory body chemicals; Those wanting to prevent undesirable cellular changes through diet KEY INGREDIENT (S): CLA from safflower oil, L-Carnitine amino acid, Guarana Seed extract (20% naturally occurring caffeine), Green Tea extract (40% polyphenols), Chromium Picolinate
MAIN PRODUCT FEATURES: Conjugated Linoleic Acid (CLA) is a derivative of linoleic acid, an essential fatty acid. The softgel is formulated with CLA (derived from safflower oil), Green Tea extract (polyphenols), Guarana extract (caffeine), L-Carnitine, and Chromium (III) Picolinate for synergistic effects of reducing body fat and increasing lean muscle mass.
OTHER IMPORTANT ISSUES: One study, titled "Efficacy and Safety of One-Year Supplementation with Conjugated linoleic Acid in Moderate Overweight," found that compared to placebo, CLA-supplemented subjects had Body Fat Mass index scores averaging 9% lower than the placebo group and had Lean Body Mass results showing lean muscle mass averaging 2% more than the placebo group. Analyses of blood tests showed no side effects over this one-year period. CLA plus Guarana reportedly reduces the size and number of fat cells in another report. CLA may also reduce insulin resistance and prevent undesirable cellular changes.
AMOUNT and HOW TO USE: One to five capsules a day, preferably with meals.
COMPLEMENTARY PRODUCTS: Alpha Lipoic Acid, Vitamin E, other Antioxidants
CAUTIONS: CLA may reduce insulin resistance, so people on blood sugar medications may not need as much of their drugs. Use with caution to avoid an overdose of your blood sugar medication when using this oil. Please notify your physician about your supplement use if you are using any drugs!
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Gaullier JM, Halse J, Hoye K, Kristiansen K, Fagertun H, Vik H, Gudmundsen O. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am. J. Clin. Nutr. 79(6):1118–1125 (2004).
Tricon S, Burdge GC, Kew S, Banerjee T, Russell JJ, Grimble RF, Williams CM, Calder PC, Yaqoob P. Effects of cis-9,trans-11 and trans-1 0,cis-12 conjugated linoleic acid on immune cell function in healthy humans. Am. J. Clin. Nutr. 80(6):1626–1633 (2004).
Aminot-Gilchrist DV, Anderson HDI. Insulin resistance-associated cardiovascular disease: potential benefits of conjugated linoleic acid. Am. J. Clin. Nutr. 79(6):1159S–1163S Suppl. S (2004).
Bassaganya-Riera J, Reynolds K, Martino-Catt S, Cui YZ, Hennighausen L, Gonzalez F, Rohrer J, Benninghoff AU, Hontecillas R. Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gastroenterology 127(3):777–791 (2004).
Bergamo P, Luongo D, Rossi M. Conjugated linoleic acid - Mediated apoptosis in Jurkat T cells involves the production of reactive oxygen species. Cell Physiol. Biochem. 14(1–2):57–64 (2004).
Bouthegourd JC, Martin JC, Gripois D, Roseau S, Tome D, Even PC. Fat-depleted CLA-treated mice enter torpor after a short period of fasting. Appetite 42(1):91–98 (2004).
Brown JM, Boysen MS, Chung S, Fabiyi O, Morrison RF, Mandrup S, McIntosh MK. Conjugated linoleic acid induces human adipocyte delipidation - Autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines. J. Biol. Chem. 279(25):26735–26747 (2004).
Cheng WL, Lii CK, Chen HW, Lin TH, Liu KL. Contribution of conjugated linoleic acid to the suppression of inflammatory responses through the regulation of the NF-kappa B pathway. J. Agric. Food Chem. 52(1):71–78 (2004).
Choi JS, Jung MH, Park HS, Song JY. Effect of conjugated linoleic acid isomers on insulin resistance and mRNA levels of genes regulating energy metabolism in high-fat-fed rats. Nutrition 20(11–12):1008–1017 (2004).
Cortes HN. CLA and body composition: Research shows conjugated linoleic acid can help maintain a healthy balance between lean muscle and body fat. Agro Food Industry Hi Tech 15(2):49–51 (2004).
Dauchy RT, Dauchy EM, Sauer LA, Blask DE, Davidson LK, Krause JA, Lynch DT. Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. Cancer Lett. 209(1):7–15 (2004).
Eyjolfson V, Spriet LL, Dyck DJ. Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans. Med. Sci. Sport Exercise 36(5):814–820 (2004).
Field CJ, Schley PD. Evidence for potential mechanisms for the effect of conjugated linoleic acid on tumor metabolism and immune function: lessons from n-3 fatty acids. Am. J. Clin. Nutr. 79(6):1190S-1198S Suppl. S (2004).
Hirao A, Yamasaki M, Chujo H, Koyanagi N, Kanouchi H, Yasuda S, Matsuo A, Nishida E, Rikimaru T, Tsujita E, Shimada M, Maehara Y, Tachibana H, Yamada K. Effect of dietary conjugated linoleic acid on liver regeneration after a partial hepatectomy in rats. J. Nutr. Sci. Vitaminol. 50(1):9–12 (2004).
Inoue N, Nagao K, Hirata J, Wang YM, Yanagita T. Conjugated linoleic acid prevents the development of essential hypertension in spontaneously hypertensive rats. Biochem. Biophys. Res. Commun. 323(2):679–684 (2004).
Kritchevsky D, Tepper SA, Wright S, Czarnecki SK, Wilson TA, Nicolosi RJ. Conjugated linoleic acid isomer effects in atherosclerosis: Growth and regression of lesions. Lipids 39(7):611–616 (2004).
Lamarche B, Desroches S. Metabolic syndrome and effects of conjugated linoleic acid in obesity and lipoprotein disorders: the Quebec experience. Am. J. Clin. Nutr. 79(6):1149S–1152S Suppl. S (2004).
Malpuech-Brugere C, Verboeket-van de Venne WPHG, Mensink RP, Arnal MA, Morio B, Brandolini M, Saebo A, Lassel TS, Chardigny JM, Sebedio JL, Beaufrere B. Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans. Obesity Res. 12(4):591–598 (2004).
McCann SE, Ip C, Ip MM, McGuire MK, Muti P, Edge SB, Trevisan M, Freudenheim JL. Dietary intake of conjugated linoleic acids and risk of premenopausal and postmenopausal breast cancer, Western New York Exposures and Breast Cancer Study (WEB study). Cancer Epidemiol. Biomarkers Prevent. 13(9):1480–1484 (2004).
Moloney F, Yeow TP, Mullen A, Nolan JJ, Roche HM. Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am. J. Clin. Nutr. 80(4):887–895 (2004).
Ochoa JJ, Farquharson AJ, Grant I, Moffat LE, Heys SD, Wahle KWJ. Conjugated linoleic acids (CLAs) decrease prostate cancer cell proliferation: different molecular mechanisms for cis-9, trans-11 and trans-10, cis-12 isomers. Carcinogenesis 25(7):1185–1191 (2004).
O'Shea M. Clarinol(TM) CLA (Conjugated Linoleic Acid): the weight of evidence supports a safe and efficacious product for weight management. Agro Food Industry Hi-Tech 15(4):24–26 (2004).
O'Shea M, Bassaganya-Riera J, Mohede ICM, Immunomodulatory properties of conjugated linoleic acid. Am. J. Clin. Nutr. 79(6):1199S–1206S Suppl. S (2004).
Rainer L, Heiss CJ. Conjugated linoleic acid: Health implications and effects on body composition. J. Am. Dietetic Assoc. 104(6):963–968 (2004).
Pure Organic Cocoa Powder
December 06, 2005 06:49 PM
New Organic Cocoa Powder from NOW is a perfect addition to any health-conscious kitchen. From holiday desserts and everyday baking, to a steaming cup of hot cocoa on those cold winter days, NOW Organic Cocoa Powder Grants you the freedom of satisfying their sweet tooth without the high amounts of sugar, fat and preservatives common to many commercially available mixes.
Each ¼ cup, 55-calorie serving contains only 2.25 grams of fat, just over 11 carbohydrates, 6.5 grams of dietary fiber, 325mg of potassium, 5 grams of protein, is completely free of cholesterol and rich in polyphenols. And of course, it has a delicious taste that young and old will love!
NOW is the leader in quality and value
October 21, 2005 08:12 AM
NOW is the leader in quality and value
“We only deal with companies that support the natural products industry and have a strong public service mission”
We couldn’t agree more. NOW has, and will continue to fight for the rights of consumers to take safe supplements. As one of the most active and influential advocates in the natural products industry, we proudly support the following industry organizations.
NFA, Citizens for health, AHPA, OTA, The Herb Research Foundation, The American Botanical Council, Consumers for Health Choice (UK), The GMO Task Force, The GMP Task Force, American Herbal Pharmacopoeia, The Campaign to label Genetically Engineered Foods, AOAC (method validation), AOCS (American Oil Chemist Society), The Dietary Supplement Education Alliance (DSEA), and More…
“Does NOW support any Charitable or public services?”
NOW is a leading recycling company and was awarded a silver medal for nutrition business journal in 2005 for our dedication to environmental and sustainability issues. We use environmental-friendly packaging and procedures to ensure that our impact on the environment is minimal. Here are just a few of the charities and originations NOW generously supports:
Local Heal Clinics and food banks, Salvation Army, Marklund children’s home, African meal-a-day fund, compassion international, vitamin angel, world relief, Indian orphanage, Hephzibah children’s home, nature conservancy, Americas second harvest, world wild life, and many more
Comprehensive Prostate Formula-the Clinical Studies
October 13, 2005 04:32 PM
Helps maintain a healthy prostate gland.
Supports normal urinary function.
Comprehensive Prostate Formula-the Clinical Studies
Saw palmetto extract is one of the world's leading herbal products for prostate support. Widely-cited clinical studies conducted over the last fifteen years suggest Saw palmetto extract can produce major improvements in prostate-related urinary function. In clinical studies, Saw palmetto extract has produced measurable improvements in urinary functions and prostate size. Quality of life scores have also improved. The results with Saw palmetto extract have been duplicated in open trials and controlled, double-blind studies.11,12,13 For example, in a large open trial, 505 men took 320 mg of Saw palmetto extract daily for three months.1 The results were evaluated with various measurements such as the International Prostate Symptom Score, the quality of life score, urinary flow rates, residual urinary volume, and prostate size. After 45 days these parameters improved significantly. After 90 days of treatment nearly ninety percent of both the doctors and patients regarded Saw palmetto extract as effective as therapy for the prostate.
The changes in prostate health that accompany middle age are related to the hormone DHT, or dihydrotestosterone, a metabolite of testosterone. DHT levels rise, and DHT binds to prostate cells, accelerating growth of prostate tissue. Saw palmetto extract has been shown to inhibit 5 alpha-reductase, an enzyme that controls conversion of testosterone to DHT.14 Experimental evidence suggests Saw palmetto extract blocks the binding of DHT to prostate cells.15 The fatty acids and sterols in Saw palmetto are believed to be responsible for these actions.14,16 These include oleic acid, lauric acid, campasterol, stigmasterol, beta-sitosterol and others. Clinical studies have used extracts containing 85 to 90 percent fatty acids and sterols.
Like Saw palmetto, Pygeum contains natural sterols and fatty acids.2 Although the mechanisms for its effect have not been clearly established, animal experiments suggest Pygeum may work by inhibiting prostate cell proliferation and reducing inflammation.17,18 In several European trials, Pygeum has successfully improved urinary function. In a large double-blind, placebo-controlled study, 263 men were given 100 mg of Pygeum extract a day for 60 days. Urination improved in 66 percent of the men taking Pygeum, compared with 31 percent on placebo, based on subjective and objective tests.19
Nettles are approved by the German Commission E as effective for relieving inflammation in the urinary tract.20 As far back as 1950, German investigators have observed favorable effects on the prostate with the use of Nettle root. These initial findings have been confirmed through case studies, as well as double-blind studies, published mainly in German medical journals. In a recent double blind study published in the journal Clinical Therapeutics, 134 men took a combination of Nettle root extract and Pygeum extract over a period of 56 days.3 Urination was significantly improved.
L-Alanine, Glutamic Acid and Glycine
As noted above, Drs. Feinblatt and Gant discovered that a combination of the amino acids L-alanine, glutamic acid and glycine has a positive effect on prostate-related urinary function.5 A controlled study of 45 men was conducted to follow up on these initial observations.21 The majority of subjects experienced complete or partial relief in urinary complaints such as nighttime urination and urgency.
2. Lawrence Review of Natural Products. Pygeum. Jan 1998. Facts and Comparisons, St. Louis, MO.
3. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses Clinical Therapeutics 1993; 15(6):1011-19.
4. Wagner, H., Willer, F., Samtleben, R., Boos, G. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots Phytomedicine 1994; 1:213-224.
5. Feinblatt, H.M., Gant, J.D. Palliative treatment of benign prostatic hypertrophy. Journal of the Maine Medical Association, March 1958:99-124.
6. Giovanni, E., et. al. Intake of carotenoids and retinol in relation to risk of prostate cancer. Journal of the National Cancer Institute 1995;87(23):1767-76.
7. Wallace, A.M., Grant, J.K. Effect of zinc on androgen metabolism in the human hyperplastic prostate. Biochemical Society Transactions 1975; 3(3):540-42
8. Badmaev, V., Majeed, M., Passwater, R. Selenium: A quest for better understanding. Alternative Therapies 1996; 2(4):59-67.
9. Fouhad, M.T. Selenium and cancer, chromium and diabetes: two trace elements that have merits as dietary supplements in human nutrition. Journal of Applied Nutrition 1979:31(1&2):14-17.
10. Vescovi, P.P., et. al. Pyridoxine (Vit. B6) decreases opoids-induced hyperprolactinemia. Horm. metabol. Res. 1985; 17:46-47.
11. Tasca, A., et. al. Treatment of obstructive symptomatology caused by prostatic adenoma with an extract of Serenoa repens. Double-blind clinical study vs. placebo. Minerva Urologica e Nefrologica 1985; 37:87-91.
12. Champault, G., Bonnard, A.M., Cauquil, J., Patel, J.C. Medical treatment of prostatic adenoma. A controlled test of PA 109 vs. placebo in 110 patients. Ann. Urol. 1984; 18(6):407-410.
13. Crimi, A., Russo, A. The use of Serenoa repens extract in the treatment of functional disturbances caused by prostate hypertrophy. Med. Praxis 1983; 4:47-51.
14. NiederprŸm, H.J., Schweikert. H.U., ZŠnker, K.S. Testosterone 5 alpha-reductase inhibition by free fatty acids from Sabal serrulata fruits. Phytomedicine 1994; 1:127-133.
15. Sultan, C., et. al. Inhibition of androgen metabolism and binding of liposterolic extract of Serenoa repens B in human foreskin fibroblasts. J. Steroid Biochem. 1984; 20(1):515-519.
16. Weissner, H., et. al. Effects of the Sabal serrulata extract IDS 9 and its subfractions on 5 alpha-reductase activity in human benign prostatic hyperplasia. The Prostate 1996;28:300-06.
17. Yablonsky, F. Nicolas, V., Riffaud, J.P., Bellamy, F. Antiproliferative effect of Pygeum africanum on rat prostatic fibroblasts. J. of Urology 1997; 157:2381-87.
18. Marconi, M. et. al. Anti-inflammatory action of Pygeum extract in the rat. Farmaci. & Terapia. 1986; 3:135.
19. Barlet, A, et. al. Efficacy of Pygeum africanum extract in the treatment of micturational disorders due to benign prostatic hyperplasia. Evaluation of objective and subjective parameters. A multicenter, randomized, double-blind trial. Wien. Klin. Wocheschr. 1990; 22:667-73.
20. The Complete German Commission E Monographs. 1998, Blumenthal, M., ed., (p.216) Austin, TX: American Botanical Council.
21. Damrau, F. Benign prostatic hypertrophy: amino acid therapy for symptomatic relief. American Journal of Geriatrics 1962; 10:426-30.
An old Indian remedy gives your teeth a new gleam - NEEM
July 27, 2005 04:23 PM
Keen on Neem
An old Indian remedy gives your teeth a new gleam.
The search for clean teeth, healthy gums and fresh breath is not just a modern obsession, but an age-old fixation. Dental historians believe that ancient cavity rates ranged from 1% among Eskimos, with their highly carnivorous diet, to 80% among members of Egypt’s royalty, who feasted on dainties that included many high-carb delights. So it’s no surprise that most ancient cultures had their favorite oral hygiene therapies.
In Indian, the tooth scrubber of popular choice was twigs taken from the neem tree. Small wonder: This tropical evergreen’s therapeutic versatility sports and impressive 4,000-year-old track record, earning it the nickname of “village pharmacy.” Indians who went abroad carried neem with them, and they put the entire tree-bark, fruit, leaf, root, seed-to health-enhancing use. One famous Indian emiGrant, Mahatma Gandhi, was a keen neem enthusiast; after returning to his native land, Gandhi held prayer meetings under a neem tree.
Today, neem’s beautiful branches grace a vast swath of the Southern Hemisphere, including Australia (which may become the biggest neem-producing nation over the coming decades), Fiji, sub-Saharan Africa, Central and South America and the Caribbean. This remarkable plant’s Sanskrit name, arista, says it all-“perfect, complete and imperishable.”
Keeping Teeth Intact
Your dentist is actually the second one to drill your pearly whites. The first drillers are the germs that reside in your mouth-or, to be more accurate, the acids these wee beasties produce. Their handiwork: dental caries, or just plain cavities. These bacteria are also responsible for gum disease, which can lead to tooth loss if unchecked. What’s even worse, low-level inflammation caused by disordered gums may create the kind of blood-vessel havoc associated with heart problems.
Neem extracts act against a variety of detrimental microbes, which may explain its time-tested success in helping to keep teeth whole. Scientists at India’s Zydus Research Centre found that individuals who used a neem dental gel twice a day for six weeks enjoyed significant reductions in both plaque-the gummy, bacteria-harboring stuff that accumulates on teeth-and gum disease (International Dental Journal 8/04).
Neem’s fame is spreading among Northern Hemisphere consumers. It is becoming an herbally aware toothpaste ingredient valued for the fresh feeling its cool astringency imparts to the mouth. Neem is also a prized component of other health and beauty products, such as bath powders, lotions, shampoos and soaps.
In India, neem is a vital weapon in the arsenal of Ayurveda, that country’s system of traditional medicine. Practitioners there mash the leaves into a paste to alleviate chickenpox and warts, and brew them into tea to break malaria’s feverish grip. The leaves also make a soothing soak for fungus-infected feet.
Indian scientists are also hard at work studying neem. They’ve distilled the substances that account for neem’s ability to fight bacteria, fungi and parasites (including the pests that infest pets). Researchers have explored neem’s other traditional usages; in one study, a bark extract was able to ease ulcers (Life Sciences 10/29/04). What’s more, neem is esteemed for its contributions to Indian agriculture; the seedcake makes a nutritious feed supplement and bees that feed on neem are free of wax moths.
If you value keeping your teeth in gleaming condition, consider neem.
Pain - Post Op and Relaxation
July 13, 2005 09:24 AM
Relaxation, Music Reduce Post-Op Pain. New research has found that relaxation and music, separately or together, significantly reduce patients' pain following major abdominal surgery. The study, published in the May issue of the journal Pain, found that these methods reduce pain more than pain medication alone. Led by Marion Good, PhD, RN, of Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, the study is supported by the National Institute of Nursing Research (NINR), at the National Institutes of Health. "This is important news for the millions of Americans who undergo surgery and experience postoperative pain each year," said Dr. Patricia A. Grady, director of the NINR.
"Better pain management can reduce hospital stays and speed recovery, ultimately improving patients' quality of life." Dr. Good and her research team studied three groups of patients undergoing abdominal surgery. In addition to the usual pain medication, one group used a jaw relaxation technique, another group listened to music, and a third group received a combination of relaxation and music.
Findings revealed that, after surgery, the three treatment groups had significantly less pain than the control group, which received only pain medication. "Both medication and self-care methods which involve patient participation are needed for relief," said Dr. Good.
"These relaxation and music self-care methods provide more complete relief without the undesired side effects of some pain medications." The findings have important implications for the 23 million people who undergo surgery and experience postoperative pain annually in the United States. Pain can hamper recovery by heightening the body's response to the stress of surgery and increasing tissue breakdown, coagulation and fluid retention. Pain also interferes with appetite and sleep and can lead to complications that prolong hospitalization.
Dr. Good and her research staff worked with 500 patients aged 18-70, who were undergoing gynecological, gastrointestinal, exploratory or urinary surgery. Prior to surgery, those in the music, relaxation or combination groups practiced the techniques. The relaxation technique consisted of letting the lower jaw drop slightly, softening the lips, resting the tongue in the bottom of the mouth, and breathing slowly and rhythmically with a three-rhythm pattern of inhale, exhale and rest. Patients in the music group chose one of five kinds of soothing music--harp, piano, synthesizer, orchestral or slow jazz.
On the first and second days after surgery, all patients received morphine or Demerol for pain relief by pressing a button connected to their intravenous patient controlled analgesia pumps. The groups receiving the additional intervention used earphones to listen to music and relaxation tapes during walking and rest, while the control group did not. The research team measured the patients' pain before and after 15 minutes of bed rest and four times during walking to see if the sensation and distress of pain changed.
Dr. Good found that during these two days postsurgery the three treatment groups had significantly less pain than the control group during both walking and rest. "Patients can take more control of their postoperative pain using these self-care methods," says Dr. Good. "Nurses and physicians preparing patients for surgery and caring for them afterwards should encourage patients to use relaxation and music to enhance the effectiveness of pain medication and hasten recovery."
Dr. Good's findings have implications for future research into the effectiveness of self-care methods on other types of pain, including chronic pain, cancer pain, and pain of the critically ill.
Vitamin D Lack Linked to Hip Fracture. Vitamin D deficiency in post-menopausal women is associated with increased risk of hip fracture, according to investigators at Brigham and Women's Hospital in Boston, Mass. In a group of women with osteoporosis hospitalized for hip fracture, 50 percent were found to have a previously undetected vitamin D deficiency. In the control group, women who had not suffered a hip fracture but who were hospitalized for an elective hip replacement, only a very small percentage had vitamin D deficiency, although one-fourth of those women also had osteoporosis. These findings were reported in the April 28, 1999, issue of the Journal of the American Medical Association.
The study, conducted by Meryl S. LeBoff, MD; Lynn Kohlmeier, MD; Shelley Hurwitz, PhD; Jennifer Franklin, BA; John Wright, MD; and Julie Glowacki, PhD; of the Endocrine Hypertension Division, Department of Internal Medicine, and Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, was supported by Grants from the National Institute on Aging (NIA) and the National Center for Research Resources (NCRR. These investigators studied women admitted to either Brigham and Women's Hospital or the New England Baptist Hospital, both in Boston, between January 1995 and June 1998.
A group of 98 postmenopausal women who normally reside in their own homes were chosen for the study. Women with bone deterioration from other causes were excluded from the study.
There were 30 women with hip fractures caused by osteoporosis and 68 hospitalized for elective joint replacement. Of these 68, 17 women also had osteoporosis as determined by the World Health Organization bone density criteria. All the participants answered questions regarding their lifestyle, reproductive history, calcium in their diet, and physical activity.
Bone mineral density of the spine, hip, and total body were measured by dual X-ray absorptiometry (DXA) technique, as was body composition. Blood chemistry and urinary calcium levels were analyzed. The two groups of women with osteoporosis did not differ significantly in either time since menopause or bone density in the spine or hip. They did, however, differ in total bone density.
The women admitted for a hip fracture had fewer hours of exercise than the control group. Fifty percent of the women with hip fractures were deficient in vitamin D, 36.7 percent had elevated parathyroid hormone (PTH) levels (a hormone which can stimulate loss of calcium from bone), and 81.8 percent had calcium in their urine, suggesting inappropriate calcium loss. Blood levels of calcium were lower in the women with hip fractures than in either elective group.
These researchers propose that vitamin D supplementation at the time of fracture may speed up recovery and reduce risk of fracture in the future. Current Dietary Reference Intake Guidelines contain a daily recommendation of 400 IU of vitamin D for people aged 51 through 70 and 600 IU for those over age 70.
"We know that a calcium-rich diet and regular weight-bearing exercise can help prevent osteoporosis. This new research suggests that an adequate intake of vitamin D, which the body uses to help absorb calcium, may help women to reduce their risk of hip fracture, even when osteoporosis is present," observed Dr. Evan C. Hadley, NIA Associate Director for geriatrics research.
"Osteoporosis leads to more than 300,000 hip fractures each year, causing pain, frequent disability, and costly hospitalizations or long-term care. "Prevention of such fractures would greatly improve the quality of life for many older women and men, as well as significantly reduce medical costs." The bones in the body often undergo rebuilding. Some cells, osteoclasts, dissolve older parts of the bones. Then, bone-building cells known as osteoblasts create new bone using calcium and phosphorus.
As people age, if osteoporosis develops, more bone is dissolved than is rebuilt, and the bones weaken and become prone to fracture. Also in many older persons, levels of vitamin D in the blood are low because they eat less or spend less time in the sun, which stimulates the body's own production of vitamin D.
Experts do not understand fully the causes of osteoporosis. However, they do know that lack of estrogen which accompanies menopause, diets low in calcium, and lack of exercise contribute to the problem. Eighty percent of older Americans who face the possibility of pain and debilitation from an osteoporosis-related fracture are women. One out of every two women and one in eight men over the age of 50 will have such a fracture sometime in the future. These fractures usually occur in the hip, wrist, and spine.
Sleep Apnea, Diabetes Link Found. Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes and more likely to suffer a stroke in the future, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published today in the Journal of Oral and Maxillofacial Surgery. Sleep apnea, a serious condition marked by loud snoring, irregular breathing and interrupted oxygen intake, affects an estimated nine million Americans. The culprit? Carrying too many extra pounds.
"The blame falls squarely on excess weight gain," said Dr. Arthur H. Friedlander, associate professor of oral and maxillofacial surgery at the UCLA School of Dentistry and associate chief of staff at the Veterans Affairs Medical Center in Los Angeles. Surplus weight interferes with insulin's ability to propel sugars from digested food across the cell membrane, robbing the cells of needed carbohydrates. Diabetes results when glucose builds up in the bloodstream and can't be utilized by the body. Being overweight can also lead to obstructive sleep apnea, according to Friedlander.
"When people gain too much weight, fatty deposits build up along the throat and line the breathing passages," he explained. "The muscles in this region slacken during sleep, forcing the airway to narrow and often close altogether." Reclining on one's back magnifies the situation. "When an overweight person lies down and goes to sleep," Friedlander said, "gravity shoves the fat in the neck backwards. This blocks the airway and can bring breathing to a halt."
Friedlander tested the blood sugar of 54 randomly selected male veterans whom doctors had previously diagnosed with obstructive sleep apnea. He discovered that 17 of the 54 patients, or 31 percent, unknowingly suffered from adult-onset diabetes. Using the same sample, Friedlander also took panoramic X-rays of the men's necks and jaws. The X-rays indicated that 12 of the 54 patients, or 22 percent, revealed calcified plaques in the carotid artery leading to the brain.
These plaques block blood flow, significantly increasing patients' risk for stroke. Seven of the 12, or 58 percent, were also diagnosed with diabetes. In dramatic comparison, the 17 patients diagnosed with diabetes showed nearly twice the incidence of blockage. Seven of the 17 men, or 41 percent, had carotid plaques. Only five of the 54 patients who displayed plaques did not have also diabetes. If he conducted this study today, Friedlander notes, he would likely find a higher number of diabetic patients. After he completed the study in 1997, the American Diabetes Association lowered its definition for diabetes from 140 to 126 milligrams of sugar per deciliter of blood.
"This is the first time that science has uncovered a link between sleep apnea and diabetes," said Friedlander. "The data suggest that someone afflicted with both diabetes and sleep apnea is more likely to suffer a stroke in the future." "Persons going to the doctor for a sleep-apnea exam should request that their blood be screened for diabetes, especially if they are overweight," he cautioned. More than half of the individuals who develop diabetes as adults will need to modify their diet and take daily insulin in order to control the disease, he added.
Stress, Surgery May Increase CA Tumors. Stress and surgery may increase the growth of cancerous tumors by suppressing natural killer cell activity, says a Johns Hopkins researcher.
Malignancies and viral infections are in part controlled by the immune system's natural killer (NK) cells, a sub-population of white blood cells that seek out and kill certain tumor and virally infected cells. In a study using animal models, natural killer cell activity was suppressed by physical stress or surgery, resulting in a significant increase in tumor development.
These findings suggest that protective measures should be considered to prevent metastasis for patients undergoing surgery to remove a cancerous tumor, according to Gayle Page, D.N.Sc., R.N., associate professor and Independence Foundation chair at the Johns Hopkins School of Nursing. "Human studies have already found a connection between the level of NK activity and susceptibility to several different types of cancer," says Page, an author of the study.
"We sought to determine the importance of stress-induced suppression of NK activity and thus learn the effects of stress and surgery on tumor development. "Many patients undergo surgery to remove cancerous tumors that have the potential to spread. If our findings in rats can be generalized to such clinical settings, then these circumstances could increase tumor growth during or shortly after surgery." The research was conducted at Ohio State University College of Nursing and the Department of Psychology at UCLA, where Page held previous positions, and at Tel Aviv University.
Results of the study are published in the March issue of the International Journal of Cancer. In laboratory studies, Page and her colleagues subjected rats to either abdominal surgery or physical stress, and then inoculated them with cancer cells. In the rats that had undergone surgery, the researchers observed a 200 to 500 percent increase in the incidence of lung tumor cells, an early indicator of metastasis, compared with rats that had not received surgery.
The experiment also showed that stress increased lung tumor incidence and significantly increased the mortality in the animals inoculated with cancer cells. "Our results show that, under specific circumstances, resistance to tumor development is compromised by physical stress and surgical intervention," says Page.
"Because surgical procedures are life-saving and cannot be withheld, protective measures should be considered that will prevent suppression of the natural killer cell activity and additional tumor development. "Researchers do not yet know how to prevent surgery-induced immune suppression, but early animal studies have shown increased use of analgesia reduces the risk."
The study was funded by the National Institutes of Health, and the Chief Scientist of the Israeli Ministry of Health. Lead author was Shamgar Ben-Eliyahu, Ph.D., and other authors were Raz Yirmiya, Ph.D., and Guy Shakhar.
HAWAIIAN NONI (Morinda citrifolia)
July 11, 2005 08:50 PM
In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:
Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.
The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.
Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fraGrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.
Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.
discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.
ROOT AND ROOT BARK
Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.
Body Systems Targeted
The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.
Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.
Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .
NONI: ITS USE AND HISTORY
Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .
Wonder Herb of Island Folk Healers
Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.
Noni’s Medical Reputation
Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.
A Timely Reemer gence
Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.
TRADITIONAL USES OF NONI
Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15
decoctions to stimulate delayed menst ruation.
XERONINE: THE SECRET OF NONI?
One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .
Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18
How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.
MODERN APPLICATIONS OF NONI
Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.
Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.
xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.
A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21
In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.
with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.
The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.
The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.
The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.
While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.
A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29
Skin Healing Agent
One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.
burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30
The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.
Complementary Agents of Noni
PrimaryApplications of Noni
June 25, 2005 08:13 PM
1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in miGrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.
GARLIC AND CARDIOVASCULAR HEALTH
June 25, 2005 09:59 AM
GARLIC AND CARDIOVASCULAR HEALTH
Recent research has supported the fact that garlic shows excellent potential in the treatment of cardiovascular diseases. Disorders of the heart and the circulatory system claim more lives than any other disease. It is the obstruction or clogging of the coronary arteries which causes more deaths that any other factor. The arteries, which supply the heart with blood and oxygen, become increasingly narrower as plaque builds up over time. When blood supply becomes so restricted that a certain portion of the heart is deprived of oxygen, a heart attack occurs.
The two greatest predictors of heart disease are high blood pressure and high blood serum cholesterol levels. Both of these determinants are directly impacted by the therapeutic action of Garlic. What is particularly relevant about the role of Garlic in coronary heart disease is that several studies done on rabbits found that even pre-existing atherosclerotic deposits and lesions could actually be reversed if garlic was consistently consumed.4
Granted, the above study has not been performed on humans, however, its implications are extremely significant. It is important to remember that it is not always what we are eating that causes heart disease, but what we are not eating. Studies like the one just described suggest that even if our diets were high in cholesterol, adding chemical compounds like the ones found in garlic may keep us from developing cardiovascular disease. This might explain why some cultural groups which consume high fat diets do not suffer the coronary consequences so typical of our population.
What is particularly exciting about the potential of garlic for anyone suffering from heart disease is that it can help reverse the disease and substantially reduce the risk of a second heart attack. The longer garlic is used, the better its results are. For example; people who have heart disease showed more improvement after the third year of garlic therapy than before. A possible explanation for this is that using garlic consistently over time progressively reverses hardening of the arteries, therefore the longer the garlic usage, the less the risk of heart attack.5 The New York Times ran an article on garlic in their September 4, 1990 edition. Concerning heart disease and garlic, it stated:
“...most exciting to those attending the conference, which was co-sponsored by Pennsylvania State and the Federal Department of Agriculture, were the results of a three year study in India among 432 coronary patients who had already suffered one heart attack. The patients were randomly divid ed into two groups, with one group receiving daily supple ments of garlic juice in milk. Those who took the garlic sup plements suffered fewer additional heart attacks, had lower blood pressure and serum cholesterol levels and were less likely to die during the study. After three years, nearly twice as many patients had died in the group not taking garlic . . . Patients who drank the garlic supplement were more likely to report such subjective benefits as an increase in vigor, energy and sexual desire, improvements in exercise tolerance, and a decrease in joint pains and asthmatic tendencies.”
PADMA BASIC: A Tibetan Herbal Formula
June 21, 2005 05:27 PM
PADMA BASIC: A Tibetan Herbal Formula
By Isaac Eliaz, M.D.
"As an integrated system of health care, Tibetan medicine can offer allopathic medicine a different perspective on health. However, like other scientific systems, it must be understood in its own terms, as well as in the context of objective investigation. In practice it can also offer Western people another approach to achieving happiness through health and balance." --His Holiness the Dalai Lama, May 16, 1997
In this article I want to discuss a Tibetan-based herbal formula that reflects the philosophy outlined by H.H. the Dalai Lama. PADMA BASIC® is an extensively researched formulation that bridges the gap between Classical Tibetan Medicine and the modern Western medical paradigm. With over 50 published scientific papers spanning the last 30 years, PADMA's popularity among Western medical professionals can be attributed to its history of safe use and its health-enhancing properties. The original formula, used for centuries as a cardiovascular tonic and to counteract "heat" (inflammatory processes or infections), made its way to Europe by the first half of the 20th century. Acceptance of an ancient Tibetan formula into the Western medical tradition requires sensitivity to both the original Tibetan intention, and the rigorous requirements of the international pharmaceutical community. Today PADMA BASIC is produced in accordance with strict manufacturing guidelines. The herbs are grown organically, or meticulously tested to ensure they are not contaminated. Ingredients are verified using thin layer or high pressure liquid chromatography. While the highest "scientific Western methods" are used, traditional Tibetan "scientific methods" of smelling and tasting are also followed.
PADMA BASIC can be understood from two viewpoints. In Classical Tibetan Medicine, good health means maintaining a dynamic equilibrium of universal elemental forces. Illness is a manifestation of imbalance. Therapeutic intervention aims at restoring balance by treating the cause, not just the symptoms. Within this traditional model, PADMA has three functions:
Ingredients: Iceland moss (Cetraria islandica), Costus root, neem fruit (Azadirachtaindica), Cardamom fruit, Red Saunders heart wood (Pterocarpus santalinus), chebulic myrobalan fruit (Terminalia chebula), Allspice fruit, bael tree fruit (Aegle marmelos), Calcium Sulfate, Columbine aerial part (Aquilegia vulgaris), English Plantain aerial part, Licorice root, Knotweed aerial part (Polygonum aviculare), Golden cinquefoil aerial part (Potentilla aurea), Clove flower, Spiked ginger lily rhizome (Hedychium spicatum), Valerian root, Lettuce leaf (Lactuca sativa), Calendula flower, Natural Camphor (Cinnammum camphora).
Dr. Isaac Eliaz is a medical doctor and licensed acupuncturist with extensive training in complementary modalities. For 15 years, his practice has centered on the integrative treatment of cancer. He has been involved in numerous studies investigating the effects of nutritional supplements on cancer and has been Granted two patents.
Scents of Balance
June 14, 2005 11:54 AM
Scents of Balance by Rosemary Sage Energy Times, January 5, 2005
Life can feel like an emotional rollercoaster, with the high-stress jitters following the low-mood blues. But aromatherapy-the healing power of scent-can restore equilibrium.
The use of volatile plant oils, including essential oils, for psychological and physical well-being dates back thousands of years. The ancient Chinese, Egyptians, Greeks and Romans used infused oils and herbal preparations for medicinal, fraGrant, cosmetic, even spiritual reasons.
During the late 20th century, people started to relearn the benefits of aromatherapy and these days, aromatherapy's reputation as a soothing, healing art continues to grow. Once you've experienced the odiferous power of aromatherapy's essential oils, you'll keep coming back for more: These gently wafting odors have the power to stimulate or calm, invigorate or relax.
When you enter this scented world, "there you will find nature in one of its most powerful forms-aromatic liquid substances known as 'essential oils,'" says Valerie Ann Worwood in The Complete Book of Essential Oils and Aromatherapy (Thorsons). Essential oils form what Worwood refers to as the "fraGrant pharmacy," a collection of concentrated substances used in pharmaceuticals, foods and cosmetics.
When you sniff the aromas of essential oils, "they enter and leave the body with great efficiency, leaving no toxins behind," Worwood points out. "The most effective way to use essential oils is...by external application or inhalation. The methods used include body oils, compresses, cosmetic lotions, baths-including sitz, hand and foot baths-hair rinses...perfumes...and a whole range of room [scenting] methods."
As Worwood explains, essential oils are produced in various parts of different plants. As a result, it takes a great deal of specialized work to extract essential oils. About 60,000 rose blossoms are consumed in the production of an ounce (!) of rose oil.
Just as the antioxidant phytonutrients we eat in vegetarian foods link our bodies to the health-promoting chemistry of plants, the penetrating nature of essential oils are thought to connect our souls to the essences of flora. "From inside comes the voice and from inside comes the scent," observed the 19th century German doctor Gustav Fechner, quoted by Robert Tisserand in The Art of Aromatherapy (Healing Arts Press). "Just as one can tell human beings in the dark from the tone of voice, so, in the dark, every flower can be recognized by its scent. Each carries the soul of its progenitor."
Fechner believed that the power of essential oils to stir our deepest emotions derives from their function as a vital means of communication in the plant world. As Tisserand asks, can't we imagine that flowers "communicate with each other by the very perfumes they exude, becoming aware of each other's presence?"
The Science Behind the Scent
While alternative medical practitioners have acknowledged the effectiveness of aromatherapy for thousands of years, only recently have conventional medical researchers begun seriously looking into how this technique works.
For instance, a study of estragole, a chemical found in basil, fennel and tarragon, determined that it could potentially ease back pain by inhibiting inflammation of the sciatic nerve. (The sciatic nerve, the longest nerve in the body, runs from the back down the leg.) The researchers discovered that estragole is "active on nerves," a conclusion that aromatherapy practitioners, who employ the scent of these oils to soothe pain, already knew. Science is verifying another piece of information long known to practitioners-that while certain essential oils can calm you down, others prod your alertness. In a study performed at the University of Northumbria in England, scientists found that sniffing the scent of lavender lulls the human brain into a comfortable, rather stupefied state, while rosemary, in contrast, can sharpen recall.
As the English researchers noted, lavender "produced a significant decrement in performance of working memory, and impaired reaction times for both memory and attention-based tasks." That's probably why the odor of lavender is noted for enhancing sleep. On the other hand, the scientists found that rosemary "produced a significant enhancement of performance for overall quality of memory and secondary memory factors." However, they did point out that under the influence of both of these oils, performance slowed when tackling a battery of memory tests. Apparently, the oils mellowed people so that they had little motivation to rush through the paperwork.
As Frazesca Watson notes in Aromatherapy Blends & Remedies (Thorsons): "The aroma of the oils directly affects our moods and emotions and sometimes our short- and long-term memory. Together with a wide range of physiological benefits, the aroma can help with emotional upsets such as depression, anxiety, nervous tension, anger, apathy, confusion, indecision, fear, grief, hypersensitivity, impatience, irritability, panic and hysteria."
Essential oils are especially helpful at defusing stress. Watson notes, "Treatments with essential oils are therefore very helpful for all sorts of stress-related problems, so common in our modern life."
As scientific research into the effects of these oils continue, conventional medical practitioners are sure to embrace them in increasing numbers. But before there were scientists around to confirm the effects of these wonderful scents, the ancient medical practitioners in Egypt and Greece attributed the origins of aromatherapy to the gods. For many people in today's overstressed world, the relaxing assurance of essential oils certainly seems heaven-s(c)ent.