Search Term: " Grape Seed Extract "
Magma Plus: The Power of Fruits and Veggies in a Drink
Date:
May 24, 2024 02:51 PM
Magma Plus: The Power of Fruits and Veggies in a DrinkImagine if you could get all your daily fruits and vegetables in just one drink. Magma Plus is a fruit and veggie powder supplement designed to provide natural energy and boost overall health. This drink mix, made from barley grass juice powder and 57 other natural ingredients, is a convenient way to get many essential nutrients all in one go. Magma Plus gives your body the vitamins, minerals, and antioxidants it needs for energy, immunity, and more.
What Is In it?Magma Plus is a dietary supplement that is rich in active enzymes, antioxidants, vitamins, minerals, amino acids, protein, and chlorophyll. Dr. Yoshihide Hagiwara discovered that "young barley grass is one of the most nutritionally balanced foods in nature." With this in mind, the creators of Magma Plus added barley grass juice powder along with a blend of other nutritious fruits, vegetables, plants, and herbs to create a potent energy drink. The product is available in two sizes: 150 grams (16 servings) and 300 grams (33 servings). Each serving contains 1.8 grams of barley grass juice extract, making it a nutrient-dense option for anyone looking to improve their daily nutrition.
Why Choose Magma Plus?Unlike many energy drinks that rely on sugar and caffeine, Magma Plus is a natural booster that contains important nutrients for energy production. It is packed with various fruit and vegetable extracts, including Siberian ginseng and barley grass. These ingredients energize you without the crash that often comes with caffeinated drinks. Some of the key benefits include:
IngredientsHere is a list of the natural ingredients found in Magma Plus:
Health BenefitsMagma Plus provides various health benefits:
How to Use Magma PlusIt's simple to add Magma Plus to your daily routine. Just stir three teaspoons into an 8 oz. glass of water or your favorite juice. Be sure not to mix it with hot liquids, as heat can neutralize the active enzymes. For best results, take it once or twice daily on an empty stomach, about 20 minutes before meals.
Customer TestimonialsDon't just take our word for it. Here are what some of our satisfied customers have to say:
Research and SourcesScientific studies support the benefits of many of the ingredients found in Magma Plus. Research shows that barley grass is rich in vitamins, minerals, and antioxidants that can help improve health. Studies have also shown the benefits of ginseng, Echinacea, and other herbs in boosting energy and immunity.
Brand InformationGreen Foods Corp., the company behind Magma Plus, has been in the health food business for many years. They are committed to providing high-quality, natural products that support a healthy lifestyle. Their gentle, temperature-controlled processing techniques ensure that the nutrients in Magma Plus remain intact and effective.
Are You Looking for Convenience When Consuming Fruits and Veggies?If you're looking for a convenient, natural way to boost your energy and support your overall health, Magma Plus is an excellent choice. With its unique blend of fruits, vegetables, and herbs, it provides a multitude of nutrients in each serving. Try Magma Plus today and experience the benefits for yourself! Buy Magma Plus Now!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6600) New Now Foods Grape Seed Extract 500mg Maximum Strength
Date:
October 27, 2022 03:46 PM
NOW® Grape Seed Extract is a highly concentrated extract with a minimum of 90% polyphenols, including oligomeric proanthocyanidins (OPCs), which are the potent water-soluble free radical scavenging compounds found in grape seeds.* A growing body of research indicates that grape seed OPCs may help to support the health of vascular, bone, kidney, brain and other tissues by supporting a healthy, balanced immune response to normal metabolic stress.* Today, we'll be discussing some of the many benefits of Grape Seed Extract and why you should consider adding it to your supplement regimen. One of the most important benefits of Grape Seed Extract is its role in supporting cardiovascular health.* Grape Seed Extract helps to maintain healthy cholesterol levels already within the normal range and promotes healthy blood vessel function.* Additionally, Grape Seed Extract helps to protect cells from oxidative damage and supports a healthy inflammatory response.* Grape Seed Extract also provides cognitive support.* Grape Seed Extract helps to promote healthy brain function and neuronal health.* Additionally, Grape Seed Extract has been shown to provide support for healthy vision and eye health.* Finally, Grape Seed Extract supports a healthy immune system.* Grape Seed Extract helps to balance the immune system and promotes a healthy inflammatory response.* Additionally, Grape Seed Extract provides antioxidant protection for cells and helps to reduce oxidative damage.* As you can see, there are many reasons to consider adding Grape Seed Extract to your supplement regimen. If you're looking for a natural way to support your cardiovascular health, cognitive function, vision, eye health, and immune system, then Grape Seed Extract may be right for you. Give it a try today and see how you feel!*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6541) The Many Benefits of Grape Seed Extract
Date:
October 25, 2022 11:46 AM
Did you know that grape seeds are actually a potent source of antioxidants? NOW® Grape Seed Extract is a highly concentrated extract with a minimum of 90% polyphenols, including oligomeric proanthocyanidins (OPCs), which are the potent water-soluble free radical scavenging compounds found in grape seeds.* A growing body of research indicates that grape seed OPCs may help to support the health of vascular, bone, kidney, brain and other tissues by supporting a healthy, balanced immune response to oxidative and metabolic stress.* The Antioxidant Power of Grape Seeds* The natural world is full of antioxidants. These nutrients scavenge harmful toxins and byproducts that can damage cells, leading to inflammation. Inflammation is a major contributing factor in numerous degenerative diseases, so it's important to do everything we can to keep it in check. Some of the best sources of antioxidants are fruits and vegetables—grape seeds included. Grape seeds are an especially rich source of antioxidants due to their high concentration of polyphenols. Polyphenols are micronutrients that have been shown to have numerous health benefits.* NOW® Grape Seed Extract is a highly concentrated extract with a minimum of 90% polyphenols, including oligomeric proanthocyanidins (OPCs), which are the potent water-soluble free radical scavenging compounds found in grape seeds.* A growing body of research indicates that grape seed OPCs may help to support the health of vascular, bone, kidney, brain and other tissues by supporting a healthy, balanced immune response to oxidative and metabolic stress.* What does this mean for your health? Preliminary research suggests that Grape Seed Extract may support cardiovascular health, cognitive function, and healthy aging.* So if you're looking for a way to incorporate more antioxidants into your diet, consider giving Grape Seed Extract a try! In Summary: NOW® Grape Seed Extract is a concentrated source of polyphenols—micronutrients shown to have numerous health benefits.* If you're looking for an easy way to incorporate more antioxidants into your diet, consider giving Grape Seed Extract a try! *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. [*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.]
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6520) The Benefits of NOW Clinical Cardio
Date:
September 30, 2022 12:37 PM
If you're looking for a comprehensive way to support optimal cardiovascular health, look no further than NOW Clinical Cardio. This powerful combination of targeted nutrients and botanicals helps promote healthy cardiovascular structures and functions.* With L-carnitine and CoQ10 to support energy production in the heart, hawthorn and MegaNatural®-BP™ Grape Seed Extract to support blood pressure already within the normal range, and MK-7 to help maintain arterial flexibility, Clinical Cardio offers a broad range of benefits for those looking to maintain a healthy heart.* How NOW Clinical Cardio Works NOW Clinical Cardio is a powerful formula that contains a combination of targeted nutrients and botanicals that are known to support optimal cardiovascular health.* The nutrients and botanicals in Clinical Cardio work synergistically to provide a comprehensive approach to maintaining a healthy heart.* L-carnitine is an amino acid that is synthesized in the liver from methionine and lysine. L-carnitine plays an important role in energy production by transporting fatty acids into the mitochondria where they can be used for fuel.* In addition, L-carnitine has been shown to support healthy heart function and protect against oxidative stress.* CoQ10 is another important nutrient for energy production, as it is involved in the electron transport chain in mitochondria.* CoQ10 levels have been shown to decline with age, so supplementation may be especially important for older adults.* Like L-carnitine, CoQ10 has also been shown to support healthy heart function while protecting against oxidative stress.* Hawthorn is an herb that has been used traditionally for centuries to support cardiovascular health. Hawthorn's primary mechanism of action is vasodilation—the widening of blood vessels—which supports healthy blood pressure already within the normal range.* Additionally, hawthorn has antioxidant activity and can help protect the heart from free radical damage.* MegaNatural®-BP™ Grape Seed Extract is a patented extract of whole red grapes that has been shown in clinical studies to help maintain already healthy blood pressure levels.* MegaNatural®-BP™ contains polyphenols—powerful plant compounds with antioxidant activity—which may help explain its beneficial effects on blood pressure levels.* MK-7 is a form of vitamin K2 that is derived from natto, a traditional Japanese fermented food. Vitamin K2 is involved in calcium metabolism and has been shown to promote arterial flexibility by keeping calcium hydroxyapatite out of soft tissues such as arteries.* By promoting arterial flexibility, MK-7 helps maintain healthy blood flow throughout the body.* Conclusion: NOW Clinical Cardio is a comprehensive formula that contains nutrients and botanicals that are known to support optimal cardiovascular health. With L-carnitine and CoQ10 for energy production, hawthorn for blood pressure support, MegaNatural®-BP™ Grape Seed Extract for antioxidant protection, and MK-7 for arterial flexibility, Clinical Cardio offers a broad range of benefits for those looking to maintain a healthy heart. Try it today!* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6476) Curcumin and Grapeseed
Date:
September 01, 2020 11:03 AM
Smoking, Chemical exposure, pesticides, nutrient deficiencies, to much sun exposure, and over the counter drugs and prescriptions can cause cancer. In the news, there are forever chemical roundup found in our water supply, it is no wonder we are laden with cancer as a society. Fortunately, a healthy cancer preventing diet along with natural plant compounds can be far more effective and cost a lot less than conventional care alone. Two top suggested natural medicines available right now are curcumin and Grape Seed Extract. These two herbs are an amazing pair, curcumin is a fat soluble herb to fight oxidation on the fatty oil side in the body and Grape Seed Extract is water soluble, making it a great antioxidant to fight oxidative stress on the water side of a cell. Cells in the body are made up of oil(fats) and water. The impact of both together on your health is virtually miraculous. Curcumin neutralizes unstable free radicals that take electrons from nearby molecules, and stop them from creating a cascade of damaged cells. It also reduces inflammation reduces inflammation markers in the body to prevent prevent tissue degradation. Curcumin has been shown to stop the changes that happen from free radical damage causing normal cells to become cancerous, and tumorous formations, and can even stop cancer from metastasizing or migrating to other parts of the body. Published studies anticancer activity have found that it can suppress breast, prostate, liver, skin, colon and lung cancer cells. Curcumin Must Be Absorbed To Be Useful One of the challenges or using curcumin for cancer prevention and treatment is that not all curcumin extracts are easily absorbable into the body. Blending curcumin in Turmeric essential oil enhances absorption and provides the additional benefits of ar-turmerone, a compound in the oil. Curcumin Makes Chemo More Effective There is big potential for curcumin when used with conventional treatment. BCM-95 curcumin, through research, has shown to sensitize human colon cancer cells to chemotherapy treatment where it would otherwise be resistant to this form of treatment. In some cases tumor recurrence rates can be as high as 60% but when treated with curcumin while under conventional treatment, curcumin boosted the effectiveness of the chemo drug 5-fluorouracil against cancer stem cells. Curcumin has great potential in conjunction with conventional cancer treatment and recovery. It has been found that as chemo treatment progresses, cancer cells become resistant to the chemo treatment and the dosage has to be increased as the treatment continues increasing the toxic side effects. Fortunately, curcumin taken in conjunction with conventional cancer treatment can improve the effectiveness of chemo and so the dosage can be lowered reducing the toxic side effects for individuals. This is good news! Curcumin Protects The Body During Cancer Treatment In a clinical study with curcumin, it showed to alleviate side effects of one of the most common treatments of prostate cancer known as external beam radiotherapy (EBRT) where the doctor uses radiation to destroy tumorous cancel cells. This sort of therapy has many side effects making it a difficult therapy for most men. I often causes sexual dysfunction, digestive problems, urinary tract pain and loss of control. The higher the radiation dosage the more effective the treatment is but this causes significant discomfort, that is why most doctors lean towards lower dosages which makes the treatment less effective. The clinical study administered 3000mg of BCM-95 curcumin that is 1000mg x 3 per day or a placebo one week before therapy started and during the treatment length. Each capsule of curcumin contained curcuminoids, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oil of turmeric, this is a full spectrum curcumin supplement. At the end of the treatment which lasted 20 weeks the most dramatic difference between the two groups in the study was urinary symptoms. The curcumin group said a 50% decrease in symptoms or side effects of the radiation. Also, researchers noted that the curcumin did not reduce the efficacy of the EBRT.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6362) Andrographis
Date:
July 30, 2019 02:31 PM
Dear Friends, I believe there’s an essential herb that everyone should be aware of, though not to many realize the powerful benefits of this near miracle botanical. This one nutrient has the ability to strengthen the immune system while also enhancing cardiovascular health, liver and kidney function, joint mobility, and much more. Recent studies have shown this herb to be three times more effective than milk thistle for liver health. And while I know there’s no miracle supplement, that can prevent all disease, there are a growing number of studies to show that this herb can promote overall health and well-being in a tremendous way. This herb, which I respect and hold in high regard, is andrographis. I believe it’s the next up-and-coming superstar in botanical medicine, and for good reason. I am not yet at liberty to give you the full details on a recent study, but I can tell you the results are impressive. The study involved treating three different groups of animals that had cancerous tumors. One group of animals was treated with curcumin, the second group was treated with french Grape Seed Extract, and the third group was treated with andrographis. And while all three herbs were beneficial in this study, andrographis proved to be the most effective in reducing the cancerous tumors in the animals. I can’t wait to share the study details when it’s published. It’s no wonder that andrographis has been used in natural medicine for years, due to its powerful antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, cancer-preventive, neuroprotective, and immune-stimulating properties. In fact, andrographis is the subject of over 800 studies in the National Institute of Health’s PubMed online database, with more to come! You’ll learn how this amazing herb:
And the benefits don’t stop there. Please take the time to read more at TerryTalksNutrition.com In Good health,
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6342) Natural antifungal remedies that reduce candida overgrowth
Date:
March 18, 2019 05:11 PM
Did you know that the most common cause of yeast infections in humans is caused by a fungi called Candida albicans? Those who have a high presence of Candida albicans can experience symptoms such as brain fog, depression, and unstable moods. Researchers have found that there are several natural remedies that can help decrease the presence of Candida albicans within our systems. Substances such as coconut oil have natural antifungal properties which help fight off any overgrowth of Candida albicans. Key Takeaways:
"If you suffer from candida overgrowth, you may experience symptoms like mood swings, leaky gut, brain fog, and depression, which can interfere with your daily life." Read more: https://www.naturalnews.com/2019-01-05-natural-antifungal-remedies-that-reduce-candida-overgrowth.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6080) The Health Benefits of Grape Seed Extract
Date:
November 14, 2016 10:20 PM
Grape Seed Extract is most commonly a waste product produced by the grape juice and winery industry. This is because Grape Seed Extract doesn't go into finished drinks. Grape seed contains a wide variety of health-enhancing ingredients like protein, carbohydrates and lipids (healthy fats). Immune systemA study done on healthy volunteers found that grape seed considerably increased the levels of antioxidants in the blood. So, another one of the benefits of grape seed is it helps boosts the immune system to fight against harmful compounds which may reduce the risk of chronic diseases including breast, stomach, colon, prostate and lung cancer.
|
Amount | %DV | |
Calories | 5 | |
Calcium (naturally occurring and dibasic calcium phosphate) | 57 mg | 6% |
Sodium (naturally occurring) | 5 mg | <1% |
Turmeric Rhizome Extract (95% curcumin) | 900 mg | |
Boswellia serrata Gum Resin Extract (85% boswellic acid) | 400 mg | |
Ginger Root Extract (5% gingerol) | 250 mg | |
Willow Bark Extract (15% salicin) | 100 mg | |
Chinese Skullcap Root Ext. (30% flavones) | 100 mg | |
Bromelain | 100 mg | |
Papain | 100 mg | |
Hops Flower Extract (Perluxan™) yielding 30 mg Humulex™ alpha-acids | 50 mg | |
Corydalis yanhusuo Tuber | 50 mg | |
Holy Basil Leaf Extract (2% ursolic acid) | 50 mg | |
Quercetin | 50 mg | |
Rosemary Leaf Extract (20% diterpenes) | 50 mg | |
trans-Resveratrols (from Polygonum cuspidatum root extract) | 25 mg | |
Masson Pine Bark Ext. (95% procyanidolic value) | 25 mg | |
Grape Seed Extract (95% procyanidins) | 25 mg | |
EGCG (epigallocatechin gallate) (from decaffeinated green tea leaf extract) | 25 mg | |
Lecithin | 25 mg | |
Black Pepper Fruit Extract (Bioperine®) | 5 mg |
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2132)
Oil Skin Treatment
Date:
February 12, 2010 12:31 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Oil Skin Treatment
Oily skin is the result of the sebaceous glands, which are the oil-secreting glands, produce more oil than is needed for proper lubrication of the skin. The excess oil is responsible for clogging pores and causing blemishes. Oily skin is most likely a result of heredity. However, it is known to be affected by factors such as diet, hormone levels, pregnancy, birth control pills, and the cosmetics that you use. Humidity and hot weather stimulate the sebaceous glands to produce more oil. However, it can occur at any age. A lot of people have skin that is oily only in certain areas and dry or normal in others. This condition is known as combination skin. Generally, the forehead, nose, chin, and upper back tend to be the areas that are more oily than other areas.
Oily skin does have some positive aspects. This type of skin is slow to develop age spots and discoloration, fine lines, and wrinkles. Often, it doesn’t freckle or turn red in the sun. It actually tans evenly and beautifully. On the negative side, oily skin is extremely prone to breakouts, even past adolescence. Oily skin also has a chronically shiny appearance, an oily or greasy feeling, and enlarged pores. The following nutrients are recommended for the prevention and maintenance of oily skin. The dosages recommended are for adults unless otherwise specified. For children between the ages of twelve and seventeen, the dosages should be reduced to three-quarters the recommended amount.
Flaxseed oil capsule or liquid in dosages of 1,000 mg daily or 1 tsp daily is helpful in supplying needed essential fatty acids. This nutrient is a good healer for most skin disorders. 25,000 IU of vitamin A for three months is necessary for healing and construction of new skin tissue. Vitamin B complex should be used as directed on the label as B vitamins are important for healthy skin tone. 1,000 to 1,500 mg of kelp should be taken daily. This nutrient is responsible for supplying balanced minerals that are needed for good skin tone.
Vitamin E should be taken in dosages of 200 IU daily or 400 IU every other day to protect against free radicals. 50 mg of zinc should be taken daily for tissue repair. This nutrient also enhances immune response. Grape Seed Extract should be taken as directed on the label, as it is a powerful antioxidant that protects skin cells. 500 mg of L-cysteine should be taken on an empty stomach, as it contains sulfur which is needed for healthy skin. 1 tsp of lecithin granules should be taken three times daily before meals. This nutrient is needed for better absorption of the essential fatty acids. SOD should be taken as directed on the label. It acts as a free radical destroyer. Tretinoin should be used as prescribed by a physician. This nutrient acts as a gradual chemical peel, unclogs pores, and speeds up sloughing off of top layers of skin. It helps to expose new, fresh skin.
Additionally, the following herbs may be beneficial: aloe vera, burdock root, chamomile, horsetail, oat straw, thyme, lavender, lemongrass, licorice root, rosebuds, and witch hazel. If you have a oily skin, washing the affected area two or three times daily will help keep the skin oil free and reduce acne along with a healthy diet low in sugar and vitamin supplements.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2125)
BerryOxidants - Food-Sourced Antioxidant Protection
Date:
April 12, 2009 11:07 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: BerryOxidants - Food-Sourced Antioxidant Protection
BerryOxidants - Food-Sourced Antioxidant Protection
- A power-packed antioxidant complex featuring standardized extracts from fruits, especially berries, as well as herbs and spices.
- This synergistic formula combines more than 30 plant-derived free radical fighters with a full 500 mg per tablet of the antioxidant vitamin C.
- Some scientific evidence suggests that consumption of antioxidant vitamins may reduce the risk of certain forms of cancer. However, the FDA has determined that this evidence is limited and not conclusive.
- Addresses six of the 12 SystemiCare™ body systems identified by Source Naturals as necessary for your optimal health: Liver/Detox (which may support longevity), Antioxidant Defense, Immunity, Circulation, Inflammation Response, and Structure/Connective Tissue.
2 tablets contain:
Vitamin C (as ascorbic acid) 1,000 mg
Grape Seed Extract (Proanthodyn™) 150 mg
Green Tea Leaf Ext (95% polyphenols, 150 mg 35% ECGC)
Turmeric Rhizome Ext (95% curcumin) 150 mg
Polygonum cuspidatum Root Ex 100 mg (8% total resveratrols)
Bromelain 100 mg
Quercetin 100 mg
Ginkgo Leaf Extract (50:1) 60 mg
24% Flavoneglycosides
Silymarin (from milk thistle seed ext) 60 mg
Hawthorn Berry Extract (4:1) 50 mg
Rosemary Leaf Extract (5:1) 50 mg
Citrus Bioflavonoids 50 mg
Lecithin 50 mg
Grape Skin Extract (20% polyphenols) 50 mg
Astragalus Root Extract (10:1) 50 mg
Cabbage Floret & Stem 50 mg
Cranberry Fruit Ext (90% solids) 50 mg
Sweet Cherry Fruit Ext (10:1) 50 mg
Holy Basil Leaf Ext (2% ursolic acid) 50 mg
Olive Leaf Ext (15% oleuropein) 40 mg
Rutin 40 mg
Lycium Fruit Extract (4:1) 40 mg
Strawberry Fruit 40 mg
Açai Fruit Juice Powder 40 mg
Organic Amla Fruit 40 mg
Pomegranate Seed Ext (40% elagitannins) 20 mg
European Elder Berry Ext (5% flavones) 20 mg
Mangosteen Fruit Rind Extract 20 mg (standardized to 95% flavonoids & 40% mangostins)
Raspberry Leaf Ext (40% elagitannins) 10 mg
White Mulberry Fruit Ext (10:1) 10 mg
Blueberry Leaf Ext (20% chlorogenic acid) 10 mg
Bilberry Fruit Ext (25% anthocyanidins) 5 mg
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1992)
Vitamins and Herbs
Date:
April 03, 2009 02:52 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Vitamins and Herbs
The whole human body is made up of cells that contain their own genetic material. In a healthy body, these cells divide at a controlled rate, growing and repairing damaged tissues and replacing dying cells. This predetermined rate of cell division is what keeps our bodies healthy. If cells keep multiplying when new ones are not necessary, a mass of tissue, often known as a tumor, is formed. This tumor can be either benign or malignant.
Benign tumors are not cancerous and can occur anywhere in the body. Benign tumors do not cause a threat to health, do not metastasize, and do not grow back if removed. Malignant tumors are cancerous and are usually serious. Often times, they can be life-threatening. Malignant tumors grow uncontrollably, interfere with normal metabolic and organ functioning, and have the ability to metastasize and invade other tissues. If a portion of a cell’s DNA is damaged, the cell can become abnormal. When an abnormal cell divides, it forms new cells that are a photocopy of the damaged genetic material. This ongoing process occurs constantly within our bodies. The majority of the time our bodies have the ability to destroy these abnormal cells and maintain a sort of cellular equilibrium. If a crucial part of the DNA is destroyed and the abnormal cells cannot be controlled any longer, cancer forms. All cancer cells have two things in common: growing uncontrollably and having the ability to metastasize. The immune system does not recognize cancer cells as dangerous or foreign.
Although the exact cause for the cell damage that initiates the cancer process is unknown (theoretically free radical damage causes DNA damage), the chain of events that leads to cancer is very complex, and each individual body reacts differently. It is a combination of genetic, behavioral, environmental, and lifestyle factors that are thought to be involved in turning normal cells into abnormal cells, and abnormal cells into cancer.
There are also factors that are believed to slow the process, while other factors can speed up the process. Possible contributors to the development and growth of cancer can be divided into three categories: external, internal, and lifestyle. External factors include unhealthy workplace environments and exposure to air and water pollution, chemicals, pesticides, and herbicides. Included in the internal factors include both genetics and infections. Lifestyle factors are those we personally can most readily control, such as diet, smoking, drinking, and sun exposure. External and lifestyle factors account for 80 percent of cancer deaths in the United States.
Just as each of us looks different, each of our bodies has its own unique composition. Some of us may react adversely to what some of us react well to. This is why some treatments prove to be successful for some, but not for others. This is why dietary wellness and prevention is so important. If we can keep our bodies healthy and avoid known cancer-causing agents, we have a good defense against cancer in the first place.
The following nutrients and supplements are designed for persons who have been diagnosed with cancer, as well as for those who wish to enhance their chances of avoiding the disease: coenzyme Q10, colostrum, DMG, garlic, IP6, melatonin, MSM, proteolytic enzymes, selenium, 7-keto DHEA, shark cartilage, SOD, vitamin A, shiitake extract, acidophilus, chromium picolinate, flaxseed oil, Grape Seed Extract, kelp, l-carnitine, multienzyme complex, a multi-mineral complex, multivitamin complex, NAC, raw glandular complex, taurine, and vitamin B complex. Additionally, the following herbs may be beneficial: astragalus, birch, burdock root, cat’s claw, chaparral, chuchuhuasi, cranberry, dandelion, Echinacea, fennel, green tea, licorice root, macela, milk thistle, parsley, pau d’arco, red clover, suma, cardamom, cayenne, ginger, rosemary, sage, thyme, turmeric, ragwort, wood sage, curcumin, essiac, noni, olive leaf extract, rosemary, and boswellia.
All of the above listed herbs and vitamins can help restore the body to good nutrition and help boost the immune system so the body can find and fight back against cancer. Natural vitamins and herbs are available at your local or internet health food store. When purchasing supplements, look for name brand vitamins like Solaray and Source Naturals to ensure you receive quality and you get what you pay for.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1986)
Green Coffee Bean Extract
Date:
October 22, 2008 04:59 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Green Coffee Bean Extract
It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs.
The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition.
However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here.
The Free Radical Theory of Aging
Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them.
Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging.
Free radicals are generated in the body in four different ways:
1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher.
2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes.
3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting.
4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products.
In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body.
So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell.
Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron.
Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals.
It has been established that green coffee bean reacts twice as fast as green tea or Grape Seed Extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol.
The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level.
Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging.
A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life.
There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.
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Vitamins Herbs And Antioxidants
Date:
October 17, 2008 09:48 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Vitamins Herbs And Antioxidants
Grilling meat over an open fire is something our ancestors have been doing for thousands of years. But people today who are indulging in chicken and cheeseburgers face a lot of concerns that our ancestors never even dreamed of. These include air pollutants and cancer-causing compounds. Research has proven that grilling meats creates two types of compounds that can lead to cancer. More so, both briquettes and lump charcoal spew hydrocarbons and soot particles as they burn, which encourage global warming contribute to many health problems. However, the majority of us cannot resist barbeque. So instead of dodging barbequed food, learn to grill without the guilt and fewer health risks.
Barbeque emissions are well below those from motor vehicles and the industry in rank, but its environmental effects are just as harmful given that burning charcoal contributes to smog and global warming. Lump charcoal is actually made from charred wood, which is a factor in deforestation. It can be compared to fuels that we use in furnaces and water heaters, such as oil, gas, and wood. Like these other fuels, charcoal produces soot when it is burned. These particles in soot are air pollutants and microscopic solids which are inhaled and deposited in the lungs. Particle pollution is associated with asthma, strokes, heart attacks, lung cancer, and reduced life expectancy. Once animal fat drips onto the flame of a charcoal or gas grill, carcinogenic compounds rise with the smoke and are deposited on the meat. Other harmful chemicals are then formed on the food as it continues to char. The more time the meat spends on the grill, the more harmful chemicals that are created. These compounds do not form on vegetables, as it is a reaction with animal-based foods that generates the harmful effects. However, any food that is over-charred contains other types of cancer-causing substances.
Grilling is a method of cooking that adds to the formation and deposit of cancer-causing substances on meat, as both substances deposited are undesirable and carcinogenic. The high heat of grill cooking produces more harmful chemicals than oven roasting or baking a lower temperature, but beef and chicken must both be cooked at temperatures high enough to destroy E. coli and other harmful bugs.
Because cancer risk is influenced much more by long-term patterns than occasional patterns, the goal is to have a diet that balances calories you take in with calories you put out, and to eat a diet containing many fruits and vegetables. Grilling less meat and more vegetables can reduce pollution on many levels. Also, vegetarian sources of protein, such as veggie burgers, contain few or no harmful chemicals when grilled. So for those summer days when a barbecue is irresistible, be sure to use natural charcoal, which is made from environmentally friendly wood sources and low-emission plant wastes.
Thankfully, all natural charcoals are chemical-free. In order to minimize cancerous compounds on the grill, cook at lower temperatures and flip meat every one to two minutes. Marinating meat or precooking it in a microwave for two minutes will also reduce hazardous compounds and carcinogenic compounds can be reduced by grilling lower-fat meats with fewer fat drippings.
By simply limiting the animal protein portion and making vegetables and grains a larger part of the meal, you can minimize the carcinogens and maximize your intake of cancer-protective vitamins and natural compounds. For most eliminating meat is undesirable, so supplementing with herbs and vitamins that help boost the immune system and act as antioxidants such as Grape Seed Extract, vitamin c, and bioflavonoids can help the body fight off those nasty carcinogens produced from grilling.
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GrapeSeed Extract
Date:
October 15, 2008 09:46 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: GrapeSeed Extract
It is possible to fight off aging with Grape Seed Extract due largely to the antioxidant effect of the phytochemicals contained within the seed of the grape. The seed is rarely absorbed by your body because it is so difficult for your digestive juices to break down; significantly more difficult than the skin or the pulp. So what is specific about the seed that makes it so useful as a source of antioxidants? That shall be discuss shortly, but for now let's discuss the causes of aging, and how antioxidants can help to keep them at bay.
To fight off aging you have to understand what causes it, and the take steps to avoid these causes. It is fairly obvious that all causes of aging cannot be circumvented, but there are things that can be done to keep some of them at bay. Here, we are specifically concerned with the aging of your skin, which is the most visible form of aging. The first aspect of aging to understand is that there are two types: intrinsic and extrinsic.
Intrinsic Aging
Intrinsic aging is natural aging, and is largely genetic. Starting when you are fairly young, normally in the early to mid 20s, intrinsic aging is typified by wrinkling, hair loss or graying of the hair, hollowing of cheeks and other areas where the fat underneath the skin that normally contributes to your physical appearance is lost, and also bone loss that causes your skin to sag due a gradual loss of the structure that sculpts your physical appearance.
The age at which this occurs, and its speed is determined by your genes; although the process generally begins around the mid 20s, the speed with which it progresses is genetically controlled.
Extrinsic Aging
This is where Grape Seed Extract can help. Extrinsic aging is not genetic, but environmental. Ten majority of this type of aging is due to exposure to the damaging UV light of the sun, which cause the typical 'leathery' look of the skin of people raised in areas such locations as the hotter parts of Australia and the USA, without the benefit of the native skin pigmentation that filters out these harmful ultra-violet rays.
Other factors that can cause the same degradation of your skin cells are smoking, the way you sleep and gravity. The sun generates free radicals (more on these later) that can destroy skin cells, cause freckles, leathery skin and a blotched complexion and also skin cancer. Smokers are more likely to develop leathery and wrinkled skin than non-smokers, and as the elasticity of your skin reduces, gravity cause jowls to develop and also a more pronounced lower lip.
Even your sleeping position can make you appear to age quicker, particularly using the same sleeping position on your pillow each night that cause what are known as sleep lines, that are really wrinkles that are difficult, if not impossible to remove. However, one of the most relevant factors is pollution, and the effects of car emissions, pesticides and other agricultural chemicals, paint fumes and 1001 other forms of chemical pollution that produce free radicals.
Where Grape Seed Extract is involved in fighting off aging is in extrinsic aging is by destroying the free radicals. All substances, from the air to the oceans, are formed of atoms that contain electrons. Stable molecules contain an even number of electrons, or what are known as 'electron pairs'. When a molecule loses one electron it is known as a free radical, whose prime purpose in its very short life is to steal an electron from the nearest molecule. This 'short' lifetime can as long as a day or as short as thousandth of a second: it depends on is size and the degree of steric hindrance to the reaction with the spare electron.
Now that the reasons for aging and the nature of free radicals are better understood it is easier for you understand why Grape Seed Extract can help to fight aging caused by the effects of free radicals on your skin.
Grape seed is a waste product of the wine industry. You cannot make wine from grape seeds, so they are removed from the final product by filtration or sedimentation. It contains a large number of phytonutrients, the most important being polyphenols in the form of flavanoids, lipids and carbohydrates. It also contains proteins that don't have much of an effect on aging. Flavonoids (also spelled flavanoids) are powerful antioxidants that destroy free radicals; they are twenty times as powerful as Vitamin E and over fifty times more powerful an antioxidant than Vitamin C.
Both of these vitamins are regarded as strong antioxidants in their own right, which is an indication of how good Grape Seed Extract is at killing free radicals. It's like a combination of Harry Callahan, Paul Kersey, John McClane and the whole of the Magnificent Seven after the scavengers in your body cells. They succeed, and do it in spades!
Not only do the ingredients of Grape Seed Extract kill off free radicals with the efficiency of a Delta Task Force, but are also anti-allergenic, anti-inflammatory, anti-cancer and anti just about anything else you can think of. However, let's have an even closer look and find out exactly what polyphenols are present in this so-called wonder juice.
Procyanadin was originally named Vitamin P in 1936 by its discoverer, Prof. Jacques Masquelier, and is believed to bond with collagen to protect you from premature aging by retaining and even improving the elasticity of your skin. An added benefit is that it also improves the elasticity of your blood vessels, and so helps to fight off the effects of high blood pressure and places less strain on your heart. The overall effect on your face is to practically give you a chemical face lift and also provide protection from the damaging effect of the UV component of sunlight through its lethal attitude towards the free radicals that UV radiation generates.
Another component of Grape Seed Extract particularly that of muscadine grapes is resveratrol; a phytoalexin that has strong anti-inflammatory properties and can also fight off the effects of aging. Phytoalexins are antibiotics produced by plants that are under attack, and, in addition to helping you age slower, confers other benefits to your body including helping your brain to carry out its work more efficiently.
All in all, Grape Seed Extract confers many benefits to your health and is also believed to possess powerful anti-cancer properties. However, it is for its ability to fight off aging that most people use it as a supplement, and in this respect it has been found to be extremely effective. Any antioxidant is of benefit to your body, but Grape Seed Extract is of particular benefit due its high antioxidant potency.
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Fiber
Date:
September 12, 2008 09:43 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Fiber
The ileocecal valve, which is made up of sphincter muscles that close the ileum, prevents toxins and other materials that are released by the appendix from entering into the small intestine. Additionally, the ileocecal valve helps to keep digested material in the small intestine until all of the nutrients have been absorbed. When the food residue is ready for elimination, the small intestine mixes bile, mucus, and other excretions with the food residue and releases it systematically through the ileocecal valve into the large intestine. This process prevents an overload of material in the intestine for the body to eliminate.
When the toxic material of the colon is able to enter back into the intestine, where it becomes rapidly reabsorbed, ileocecal valve syndrome occurs, which can lead to infection and disease. Symptoms of ileocecal valve syndrome include constipation, diarrhea, fatigue, irregular bowel movements, lower right bowel tenderness, acne, immune weakness, migraines, and duodenal ulcers.
To avoid ileocecal valve syndrome one should eat a diet that is high in fiber and includes whole grains. These whole grains should be soaked and cooked in order to avoid irritating the valve. Foods that cause constipation such as diary products, meat, and bananas should be avoided. Raisins, figs, and stewed prunes should be eaten for breakfast. More fresh fruits and vegetables should be added to the diet. Softer raw vegetables such as leaf lettuce, spinach, avocados, sprouts, and tomatoes should be used first.
Additionally, one should reduce the amount of meat that they eat and take a fiber supplement in order to avoid constipation. Fasting on juices two or three days a week will help to speed the healing process of the digestive tracts. Grains that are thermos-cooked are healing on the digestive tract and rich in enzymes, vitamins, minerals, and protein. The slow cooking process protects the body from destruction of vital enzymes. Milet, buckwheat, and basmati brown rice can also be eaten for breakfast, as they are easy for the body to digest and extremely nourishing. Raw vegetables and fruits, steamed vegetables, yams, and avocados are all also extremely helpful in healing the digestive tract, so they are recommended.
Nutritional supplements that can assist with ileocecal valve syndrome include antioxidants, vitamin A, B-complex, vitamin C with bioflavonoids, calcium, magnesium, essential fatty acids, blue-green algae, acidophilus, and plant digestive enzymes. Also, aloe vera juice, cat’s claw, Grape Seed Extract, pau d’arco, licorice, goldenseal, slippery elm, and comfrey are great herbal aids for helping for ileocecal valve syndrome.
Colon health is a lot more important than most people realize, as the digestive process is directly related to the health of the body, immune system function, and overall longevity. When any disease occurs, the colon should be the first thing looked to for treatment. By understanding what it means to have a healthy colon, adding fiber, nutritional supplements, herbal aids, and a change in diet, one can promote overall colon health. Eating habits should be changed slowly and unhealthy, nutrition robbing foods should be eliminated from the diet and replaced with whole grain foods, fruits, and vegetables.
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Rescue From High Cholesterol
Date:
July 01, 2008 05:22 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Rescue From High Cholesterol
Cholesterol is an unsaturated waxy solid that is manufactured in the body and has important functions relative to cell membrane management. It is also known to help produce bile to digest fats and can help in metabolizing fat-soluble vitamins. Cholesterol is both made in tissue membranes and derived through the diet. This is where the basis of good and bad cholesterol comes into play. Cholesterol that is made in tissue membranes is transported by high-density lipoprotein (HDL), which delivers the cholesterol to the liver. HDL is thought to remove cholesterol from arteries and delivers it back to the liver for processing. Increased levels of HDL have also been deemed as protective against heart disease. Low-density lipoprotein (LDL), on the other hand, is dietary cholesterol that is transported and carries cholesterol from the liver to tissue membranes.
This factor is not what makes LDL cholesterol bad, instead it is the amount of cholesterol in the wrong place at the wrong time. Large amounts of cholesterol and LDL in the arteries can lead to plaques that gradually damage arteries over time, which leads to heart attack, stroke, or some other type of heart and vascular diseases. Because of these reasons, cholesterol management for heart and vascular health focuses on lowering LDL cholesterol. What is often overlooked is the value of raising HDL cholesterol levels, which can improve removal of cholesterol from dangerous locations in the arteries.
The diet greatly influences health, and by addressing macro and micro nutrients, cholesterol health can be greatly reduced. Macro nutrients that affect cholesterol include fiber, protein, and fats. Micro nutrients are things such as vitamins and minerals, especially those that have potent antioxidant mechanisms, which can affect lipid peroxidation. Fiber, which has long been recommended by the American Heart association (AHA), lowers total and LDL cholesterol levels, while raising HDL levels. Although fiber is straightforward, the trick with protein is to always find a good source that does not have saturated fat and cholesterol that can negate its benefits. Although whey protein is animal-based, it has been shown to lower LDL cholesterol. However, many people have looked to soy to provide cholesterol-managing protein.
When it comes to natural products, there are a few key nutrients that can help with cholesterol management. Among these are DHA, EPA, Omega-3s and 6s, Vitamin E, Vitamin B, and Niacin. Limiting oxidative stress and lipid peroxidation are also important components of cholesterol management. Although micro nutrients give a good level of protection from oxidation, a large amount of antioxidant fighters comes from botanicals, flavonoids, and carotenoids. Some flavonoids that can help with cholesterol care include cocoa, tea, and fruit.
Citrus bioflavonoids also help with antioxidant management, especially when they are combined with vitamin E. Fruits such as pomegranate and Grape Seed Extract help to limit LDL oxidation. Botanicals such as garlic, which contain antioxidant constituents help to lower total and LDL cholesterol while still maintaining HDL levels. Other suggestions to help maintain healthy cholesterol levels include pine bark extract as well as some types of algae.
Whether you’re attempting to use just one or many of these approaches to battle cholesterol levels, there are many well-researched ways to both lower the bad and raise the good cholesterol.
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Grapefruit Seed Extract
Date:
May 06, 2008 05:14 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Grapefruit Seed Extract
Grapefruit seed extract is regarded as being natural antibiotic that is effective against a broad range of bacterial infections. It has also been used to treat parasitic infections and a range of viral infections as well as having found uses for a wide variety of medical conditions.
So what is it about grapefruit seed that is so special? Most people are acquainted with grapefruit, which as a member of the citrus family of fruits, and not to be confused with grapes which are a totally different type of plant. Grape Seed Extract is also a useful natural medication, but used for totally different conditions.
Because of its efficacy against parasitic and viral infections, grapefruit seed extract is very useful in treating various forms of food poisoning. But, how was this remarkable property of the simple grapefruit seed noticed? The answer to that depends very much upon what version of the story of Einstein Laureate physicist and immunologist Dr. Jacob Harich you believe.
Dr. Harich was not only a scientist but a hobby gardener in Florida, and the two versions of his story tell either that he decided to investigate why grapefruit seeds tasted so bitter, or why the grapefruit seeds in his compost heap failed to compost, or rot. Whichever story is correct, and perhaps both are, the result was the discovery that grapefruit seeds appeared to be a very effective antibiotic.
In fact it has been shown to be effective against over 800 strains of bacteria and viruses and also effective against many fungi that lead to illness in humans. Because of this it is used in cased of food poisoning that involve bacterial infection of the gastrointestinal tract. In fact during the latter part of the 1980s, grapefruit seed extract was tested against a number of known antibiotics and found to be as effective as any of them. Similar results obtained in a number of tests in the USA and elsewhere in the world, and it appears that it is an excellent treatment for the symptoms of food poisoning.
Not only that, but it has been found effective in the treatment of some immunodeficiency diseases, presumably because its antimicrobial properties does much of the work that the immune system would normally do, and so relieves it of much of its hard work. This allows the immune system to concentrate on conditions which are exacerbated by deficiencies in its operation.
Bifidobacteria and Loactobacilli are bacteria that are beneficial to the digestive system. The measure of a good broad spectrum antibiotic is that it does not affect the beneficial bacteria, and grapefruit seed extract has no effect on the former and only a mildly inhibiting effect on the latter. It is also non toxic to humans, which is another measure of a good antibiotic. You would have to drink about two pints of the extract, around 4000 time the normal dose, for the treatment to be potentially fatal.
Among the many uses of the extract are not only in controlling gastrointestinal infections, but also general fungal conditions of the skin, vaginal infections and yeast infections, and also colds and sore throats. It is also believed to support the immune system, not only by its antimicrobial properties but through its effect on intestinal health upon which much of our immune system is dependent. It can also protect patients with symptoms of AIDs and other immunodeficiency conditions from infection.
Its effect on yeast infections around the nether regions of small children has been documented, and it has also been found to be very safe to young children. In fact many mothers have it as a permanent addition to their medicine cabinet.
It is not that long ago when doctors believed all diseases to be due to bacteria or viruses. It is now becoming clear that a large proportion is actually due to fungal infections and parasites. Many conditions such as allergies, circulatory disease and some forms of arthritis have been shown to be due to fungal infections that weaken the immune system. Grapefruit seed extract has been found to be effective in treating many types of fungal disease.
In using the extract in this way, and to treat bacterial infections, it is best to start with a low dose and gradually increase it. This is because when fungi and bacteria are destroyed they release toxins, and too high a dose could result in too much toxin being produced for your body to handle. If you take it gradually you will get the same result, but without the risk of the nausea and diarrhea which the toxins can cause.
Despite all of these benefits, grapefruit extract has not been given the credit it deserves, and much research has still to be done to establish the constituents of the seed that confer these properties. Among these are known to be proanthocyanadins, a class of flavanols with strong antioxidant properties, and a diphenol hydroxybenzene complex that destroys bacteria through the cytoplasmic membrane to prevent the uptake of amino acids and cause leakage of the cell contents. Other active components are Vitamins C and E, tocopherols, limonoids and sterols, in addition to a number of important minerals.
However, there is still much work to be done, although the extract will continue to be used by many devotees for the treatment, not only of food poisoning symptoms, but also of conditions such as acne, athlete’s foot, gingivitis, cold sores, sinusitis and parasitic infections. It appears to be practically a cure-all.
There appear to be no drug interactions, although some medications do react with grapefruit juice, such as some treatments for high blood pressure. If your treatment advises you not to take grapefruit juice, then do not take grapefruit seed extract. Another factor to be aware of is that since the extract is an effective bactericide, then it could deplete the digestive tract of friendly bacteria essential for digestion. You are advised, therefore, to take a supplement of acidophilus, which is easily taken in the form of yoghurt type drinks specifically formulated or dietary supplement for the purpose.
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(OPC) Grape Seed Extract
Date:
May 03, 2008 12:49 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: (OPC) Grape Seed Extract
Back in the early 1930’s scientists discovered that proanthocyanidins found in grape seeds, green tea, and several other foods are powerful antioxidants that can help the body fight free radicals. Over the year’s research continued to mount on the benefits of proanthocyanidins and in the 1990’s grape seed took the spot light.
Research studies suggested in the 1990’s that moderate use of red wine daily has significant health benefits and mainstream press popularized this notion. Supplement manufactures jumped on the bandwagon and produced a product that was alcohol free with the same benefits of drinking red wine. This was good news for those who don’t want to drink on a regular basis but the manufactures didn’t back up their product with any research at that time.
Proanthocyanidins are a group or class of flavonoids found in many plants as discussed above. Scientists discovered polymecric and oligomeric proanthocyanidins (OPC), but the oligomeric has a smaller molecular weight and can pass through the intestinal walls easier than the polymecric proanthocyanidins (PPC). This means that if you are not consuming the OPC extract for of grape seed then you are probably getting very little benefit from the supplement.
If you are taking a Grape Seed Extract supplement and there is no OPC listed on the label, the manufacture is most likely just tableting or encapsulating crushed grape seeds that aren’t standardized to the most active form OPC. This will dramatically reduce the cost of Grape Seed Extract, so if you see a low prices Grape Seed Extract at your health food store, be weary of the product if it doesn’t say OPC.
When one consumes true OPC Grape Seed Extract, one can experience many health benefits including cardiovascular benefits. Have you had your OPC Grape Seed Extract lately?
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Supports Healthy Blood Pressure
Date:
April 18, 2008 03:59 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Supports Healthy Blood Pressure
- A comprehensive Bio-Aligned Formula™ that can help maintain blood pressure already within the normal range, when used as part of a healthy diet and exercise plan.
- A complex array of 35 nutrients, botanicals and special ingredients provides balanced support for blood pressure.
- Supports two of the most important SystemiCare™ metabolic systems identified by Source Naturals as critical for your optimal health: Heart/Circulation (including healthy blood vessels, blood flow, homocysteine levels, and blood lipid regulation) and Antioxidant Defense.
3 tablets contain:
(Vitamin C (as ascorbic acid) 45 mg
Vitamin D-3 (as cholecalciferol) 240 mg
Vitamin B-6 (as pyridoxine HCl) 24 mg
Folate (folic acid & calcium folinate) 480 mcg
Vitamin B-12 (as methylcobalamin) 600 mcg
Magnesium (magnesium oxide, chelate & succinate) 240 mg
Selenium (as L-selenomethionine) 120 mcg
Potassium (as potassium citrate) 59 mg
L-Arginine (as L-arginine HCl) 1.44 g
L-Citrulline 360 mg
Hibiscus Flower Ext (20% total acids) 120 mg
gamma-vitamin E Complex 90 mg
L-Taurine 60 mg
Masson Pine Bark Extract(95% procyanidolic value) 60 mg
Garlic Clove 60 mg
Freeze Dried White Onion Bulb 60 mg
Arjuna Bark Ext (0.5% arjunolic acid) 60 mg Ashwagandha Root Extract(5% withanolides) 60 mg
Forskohlii Root Extract(ForsLean®) (20% forskohlin) 60 mg
Guggul Extract (10% guggulsterones) 60 mg
Grape Seed Extract (Proanthodyn™) 48 mg
Chinese Salvia Root Extract (MSV-60®)
(60% magnesium salvianolate B) 45 mg
Ginkgo Leaf Extract (50:1)
24% Flavoneglycosides 36 mg
Hawthorn Berry Extract (4:1) 30 mg
Hawthorn Leaf and Flower Extract (4:1) 30 mg
Olive Leaf Ext. (15% Oleuropein) 30 mg
Trimethylglycine (TMG) 30 mg
Total Resveratrols (from Polygonum cuspidatum) 24 mg
Nattokinase (NSK-SD™) 21 mg
Coenzyme Q10 18 mg
Tocotrienol Complex (Tocomax®) 12 mg
Lycopene 3 mg
Suggested Use: 3 tablets mid-morning and 2 tabs mid-afternoon between meals on an empty stomach.
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Systemic C
Date:
April 08, 2008 08:41 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Systemic C
A unique blend of compounds, including alpha-lipoic acid, N-acetyl cysteine, quercetin, and Grape Seed Extract, which is designed to reactivate and recycle vitamin C in the body, making it more available for immune support and free radical scavenging.
- Antioxidants support clear blood flow, cardiovascular health, healthy inflammatory response and immune support.
- Uses non-acidic form of Vitamin C (calcium ascorbate), recommended for individuals with acid sensitivity.
The well-known benefits of vitamin C are recharged in this formula, which is designed to make more vitamin C available for immune support and free radical scavenging. The unique blend of compounds in systemic C may reactivate and recycle vitamin C in the body, providing increased antioxidant activity for healthy aging, heart health and immune support.
Vitamin C (as calcium ascorbate) 1 g
N-Acetyl Cysteine 120 mg
alpha-Lipoic Acid 100 mg
Quercetin 50 mg
Bioflavonoids 40 mg
Grape Seed Extract (Proanthodyn™) 30 mg
Suggested Use: 2 capsules/tablets 1 to 2 times daily.
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Systemic C - Vitamin C with Optimized Vitamin C Activity!
Date:
March 28, 2008 04:22 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Systemic C - Vitamin C with Optimized Vitamin C Activity!
What could be even better than vitamin C? source naturals systemic C, of course, a vitamin C that is designed to upgrade the important benefits of this powerful antioxidant. The systemic C formula is designed to make more vitamin C available for immune support and free radical scavenging.
After vitamin C carries out its antioxidant function of neutralizing free radicals, it is oxidized and spent. The unique blend of compounds in systemic C, including alpha lipoic acid, n-acetyl cysteine, quercetin, and Grape Seed Extract, helps to reactivate and recycle vitamin C in the body. this provides the body with increased antioxidant activity, an upgraded, robust C for healthy aging, immune, heart, and skin health. Reactivating vitamin C allows this important vitamin to continue its vital functions.
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Goji Berry Elixir Antioxidant Rich Tonic
Date:
January 26, 2008 08:25 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Goji Berry Elixir Antioxidant Rich Tonic
• Nutrient-rich goji extract
• Renowned longevity tonic from China
• Provides powerful antioxidant protection
• Helps maintain visual acuity
Goji is highly revered as a general health-promoting longevity tonic and has been used in Chinese herbalism for thousands of years. The antioxidants in Goji Berry Elixir support cholesterol wellness, healthy circulation and normal cellular metabolism. The addition of seven additional fruit concentrates enhances the many health benefits which goji provides. Planetary Herbals Goji Berry Elixir™ is a highly concentrated source of goji (Lycium barbarum) which is rich in polyphenols, carotenoids and other antioxidants.
1 fl oz contains:
Vitamin C (as ascorbic acid) 60 mg
Proprietary Goji Fruit Blend: 15 g
Goji Berry Concentrate, Apple Concentrate, White Grape Concentrate, Pear Concentrate, Cranberry Concentrate, Elderberry Concentrate, Grape Seed Extract.
Suggested Use: 1 ounce twice daily.
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Hyaluronic Acid Double Strength 100mg – w/ Proline, Alpha Lipoic Acid & GrapeSeed extract.
Date:
April 04, 2007 09:38 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Hyaluronic Acid Double Strength 100mg – w/ Proline, Alpha Lipoic Acid & GrapeSeed extract.
Hyaluronic Acid has emerged as one of the most significant anti-aging supplements in the natural products industry. As a mucopolysaccharide that occurs naturally within the human body, the highest concentrations of Hyaluronic Acid are found in the skin, eyes, and articular cartilage. Hyaluronic acid works by absorbing water within the body, which in turn supports the formation of effectiveness of the gel-like matrix that protects healthy cell structures from dehydration and free radical damage. Ongoing studies continue to suggest that it may help support some of the body’s most vital functions.*
Strong, Healthy Joints
At birth and well into our youth, the human body produces ample amounts of Hyaluronic acid. These levels decline, however, based on our physical activity levels, dietary habits, and other hereditary and environmental factors. Hyaluronic acid is a key component of synovial fluid and cartilage, and serves as one of the body’s most vital natural lubricants. Joint structures lack blood vessels, and there for relay on Hyaluronic acid to transport fluids and nutrients. Many structural and articular challenges have been traced back to insufficient Hyaluronic levels.
Wrinkles and Fine Lines
Healthy, wrinkle-free skin requires a constant supply of water. Without enough, dermal cells located deep below the skin’s surface can becomes deprived of the compounds they need, thus leaving the skin dry and dehydrated. Hyaluronic acid attracts and binds large amounts of water at the cellular level to ensure that the skin has everything it needs to remain smooth, elastic, and youthful-looking.
Some published reports suggest that a child’s ability to produce abundant amounts of Hyaluronic acid may explain why they heal so quickly, often without permanent scarring. Because of the many roles it plays within the body’s connective and epidermal tissues, Hyaluronic acid is becoming more and more accepted as a way to help encourage the body’s natural wound-healing processes.
Vision and Eye Health
In addition to cartilage and synovial fluid, the eyes contain some of the body’s highest concentrations of Hyaluronic acid. In fact, the vitreous humor (the Eye’s Core) is made up almost entirely of Hyaluronic acid. This gel-like structure absorbs shock, supports vision, and protects the retina from being damaged. It is believed that many common vision and ocular problems may be a result of poor Hyaluronic acid production during adulthood.*
Each Vcap contains 100mg of Hyaluronic acid, along with Alpha Lipoic Acid, standardized Grape Seed Extract, and pharmaceutical grade L-Proline for support. Compare Now’s 100mg formula to some 50mg formulas that do not include supporting antioxidants for the same price, and the choice is clear!
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Red Wine Extract with Resveratrol - Powerful Antioxidant Protection
Date:
December 11, 2006 12:27 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Red Wine Extract with Resveratrol - Powerful Antioxidant Protection
Polygonum cuspidatum Root Standardized Extract 1 g
Yielding: Total Resveratrols 80 mg
Resveratrol 20 mg
Red Wine Extract 600 mg
Grape Seed Extract (Proanthodyn™) 50 mg
Grape Skin Extract (20% polyphenols) 50 mg
Green Tea Leaf Extract (95% polyphenols, 35% EGCG) 50 mg
Quercetin 20 mg
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Ultimate Mangosteen Liquid
Date:
February 10, 2006 10:31 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Ultimate Mangosteen Liquid
Manufactured by Trace Minerals Research Ultimate Mangosteen is a dietary supplement with a special blend that includes the exotic Mangosteen, goji berries, pomegranate, blueberry concentrate, Grape Seed Extract, grape skin extract, canberry concentrate, lychee concentrate, red grape concentrate, and mixed fruit concentrates that offer a myriad of health-giving substances to promote good health. The Mangosteen is a native fruit from south east asia that contains several classes of powerful phytonutrient antioxidants, including xanthones. Our Formula has over 30,000 ORAC Value (ORAC - Oxygen Radical Absorbance Capacity). | |
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Your Cells Supercharge Your Cells
Date:
December 20, 2005 11:30 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Your Cells Supercharge Your Cells
Your Cells Supercharge Your Cells
The differences between aging and growing old are poles apart. Sure, they may sound similar in nature. But when you think about it, the two are as different as night and day. Growing old is about retirement and travel and enjoying what you’ve worked an entire life for. Aging, on the other hand, summons images of wrinkled skin, brittle joints, cloudy minds and medicine cabinets full of prescriptions. It’s safe to assume that the majority of us want to look, live, and feel better as we grow old. Not the opposite. Many of us are on the right track - committed to a healthy lifestyle that includes regular exercise and a well-balanced diet. And yes, these do serve as a solid foundation for good health during our golden years. It is our cells, however, that ultimately determine who grows old, and who just ages.
Still, slowing the proverbial hands of time is not all about health clubs and organic produce. If you want to grow old gracefully, you must nurture the ten trillion cells that defi ne you physically. Why? Because these cells are constantly under attack by free radicals - unstable molecules that either lack, or have an unpaired number of electrons. They scour the body in search of stable cells, and do whatever they can to rob them of their electrons, a process more formally known as oxidation. Considering that it’s environmentally impossible to completely avoid contact with the billions of airborne toxins that cause free radicals, the only other option is to safeguard your healthy cells. Making the commitment to a healthy lifestyle is the fi rst step in the process, and can be accomplished by eating healthier foods, exercising on a regular basis, and paying close attention to what you are exposed to environmentally.
The next step is to nourish and protect your cells. The best way to do this is to consume foods that are rich in antioxidants and other cell-friendly nutrients. Unfortunately, this task is often much easier said than done. Today’s average adult is busier than ever, making it far more diffi cult to consume fresh, unprocessed meals 100% of the time. This does not, however, imply that all hope is lost. Over the years, the nutritional sciences have made stunning advances that afford you the opportunity to live your life while still safeguarding the integrity of your most basic building blocks. Here are a few of the best.
Antioxidants
Antioxidants work at the cellular level to paralyze the free radicals that cause oxidation throughout the body. Some of today’s most popular nutrients and dietary supplements fall into this category. They include vitamins A, E, and C, Selenium, Zinc, Alpha Lipoic Acid, Lycopene, Lutein, CoQ10, in addition to a host of others. And though similar in function, each of these free radical fi ghters has a unique role within the body.
Take CoQ10 for example. It’s present in every cell of the body, and is especially important for cardiovascular support. Lutein has been used extensively to prevent oxidation in the macular regions of the eyes. Zinc is a powerful immune system booster that has become extremely popular during cold and fl u season. Alpha Lipoic Acid is both fat and water soluble, and is commonly referred to as the “universal” antioxidant based on its ability to quench free radicals anywhere in the body.
Immune Boosting Herbs
Herbs such as Astragalus, Olive Leaf, Rhodiola, Echinacea, Panax Ginseng and Ashwaganda have been used for centuries to help support healthy cells and strong, responsive immune systems. They’ve also been shown to exhibit natural synergistic effects when used together. Today, they remain one of the most popular ways to naturally promote all-around wellbeing. When it comes to supporting healthy cells, NOW is pleased to offer one of the best selections of antioxidants, herbs and immune support formulas. Be sure to look for these and other great products at fi ne health food retailers, nationwide.*
OPCs
OPCs (proanthocyanidins) are high-powered polyphenol antioxidants that belong to the fl avonoid family. Grape Seed Extract, pine bark extracts such as pycnogenol and enzogenol, bilberry, gingko biloba, resveratrol and others all fall into this category. Research continues to suggest that OPCs work in the same manner that traditional antioxidants do, however their ability to eradicate free radicals is much greater and more versatile. Equally appealing, OPCs can easily cross the blood barrier of the brain to help protect brain and neural tissues from the damage caused by oxidative stress.
Mushroom Extracts
Throughout history, many civilizations have relied on organic mushroom extracts to encourage wellness. What we know now is that mushrooms such as Shiitake, Maitake, Reishi and others are rich in 1,3 Beta-glucans - soluble fi ber compounds that help support both innate and adaptive immunity. In addition, the active compounds in some mushrooms have been shown to stimulate the production of microphages, T cells, and other natural killer cells. These biological warriors serve at the front line when it comes to responding to bacterial attacks. They are of immeasurable value to the immune system, though drastically lacking in today’s average diet. In just the past few years, more and more healthconscious individuals have learned fi rst-hand how benefi cial they can be in the preservation of healthy cells.
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Pomeratrol™ Fact Sheet
Date:
December 19, 2005 09:09 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Pomeratrol™ Fact Sheet
Pomeratrol™ Fact Sheet
Neil E. Levin, CCN, DANLA 9/28/04USER: Those needing antioxidant protection; People with a family history of cell growth abnormalities; Anyone concerned with aging
KEY INGREDIENT(S): Pomegranate fruit standardized extract 200 mg. (Punica granatum) containing 80% total polyphenols, including 40% Ellagic acid, Resveratrol (100% trans-resveratrol) 20 mg. from a blend of Japanese knotweed root extract (Polygonum cuspidatum) and grape skin extract (Vitis vinifera)
POTENTIAL BENEFITS: Ellagic acid is a polyphenol compound found in raspberries, strawberries, pomegranates, and other fruit. It has been shown to normalize cell death of abnormal cells, a process called apoptosis. This enhances the body’s cell growth control system by providing an important plant substance. It may bind to DNA to prevent damage to this all-important genetic material. This is a key step in preventing cell damage that leads to signs of aging.
The American Cancer Society says that research in animal and laboratory models has found that ellagic acid inhibits the abnormal growth of certain cells. Research at Ohio State University indicates that berries typically contain a few milligrams per ounce of ellagic acid, the actual level varying quite a bit from variables such as species, variety and growing conditions.
Resveratrol is an antioxidant compound that is a phytoestrogen, or plant estrogen, which is protective of hormone-mediated cells in the body. Resveratrol is a potent antioxidant if stabilized. If not stable, it may quickly metabolize out of the body. This compound is believed responsible for some of the beneficial effects of moderate red wine drinking on the cardiovascular system. Resveratrol is also considered to be beneficial to smokers’ lung tissue if it is stabilized to last long enough in the system to be transported there. Resveratrol is also an inhibitor of the COX-2 inflammatory enzyme and encourages cell death (apoptosis) of abnormally growing cells. In insect experiments resveratrol even repaired DNA, leading to a longer life for healthy cells even as it helped get rid of unhealthy cells. Again, this ability to protect cells and help the body rid itself of abnormal cells is a key factor in preventing signs of aging. One liter of red wine contains between 1.5 and 3 mg. of resveratrol.
OTHER IMPORTANT ISSUES: Resveratrol is a difficult substance to stabilize. Because of the difference between resveratrol produced in the oxygen-poor environment in red wine and the form of resveratrol in unstabilized supplements, it has long been thought that resveratrol supplements were not very effective in comparison with wine. Knowing the importance of how a resveratrol supplement is metabolized, Now’s scientific staff has recently developed a special technique of stabilizing this compound in order to have an antioxidant effect closer to drinking a good glass of wine. While both trans and cis forms of resveratrol are naturally occurring, most of the recorded health benefits are attributed to the trans form. Now’s Pomeratrol provides trans-resveratrol.
DOSE: One capsule per day. Resveratrol has been used safely in studies at doses equivalent to 500 mg./day.
COMPLEMENTARY PRODUCTS: Other antioxidants and plant compounds: Vitamin C, pycnogenol, Grape Seed Extract, and alpha lipoic acid.
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. There are some indications that resveratrol is a mild anticoagulant ("blood thinner"), and it also may help keep blood vessels to remain open and flexible. Caution should be used by those on blood-thinning drugs. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
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Vitaberry Plus + Super Fruit Antioxidant
Date:
December 07, 2005 05:43 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Vitaberry Plus + Super Fruit Antioxidant
Vitaberry Plus +™ Super Fruit Antioxidant
By Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape Seed Extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),- Catalase (neutralizes peroxides),
- Functions similar to reduced Glutathione (GSH),
- Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent),
- Functions similar to Glutathione S-transferase (GST),
- Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/
ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697
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VitaBerry Plus+ Fact Sheet
Date:
December 07, 2005 05:38 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: VitaBerry Plus+ Fact Sheet
VitaBerry Plus+ Fact Sheet
Neil E. Levin, CCN, DANLA 3/18/05LIKELY USERS: Antioxidant users who want the best food source formula; People seeking polyphenols or ellagic acid supplements; Those who don’t eat fruit and want some of their benefits
KEY INGREDIENTS: VitaBerry extract, Hi-Active Orange Extract, Pomegranate Extract (420 mg) (400 mg) (100 mg)
MAIN PRODUCT FEATURES: This is a high antioxidant (high ORAC: 2,500 units per serving of oxygen radical absorbing capacity), proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry extract, Grape & Grape Seed Extract, Raspberry & Raspberry seed extract, Cranberry, Prune, Tart Cherry, Wild Bilberry extract & Strawberry powder. Fortified with Hi-Active Orange Extract (Freeze-dried Orange (Citrus sinensis) powder with minimum of 40% vitamin C) and Pomegranate Extract (80% Polyphenols and 40% Ellagic Acid).
Provides a broad-spectrum antioxidant blend with phytochemicals such as anthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol etc. in a single “0” size vegetarian capsule. There is a synergistic effect of mixing fruit antioxidants that provides antioxidant protection greater than is predicted by measuring each fruit source used in the mix individually.
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: There will be some natural variation in color, taste and odor from these fruit sources. A special freeze drying technique preserves the antioxidant value of whole fruits in a concentrated form.
SERVING SIZE & HOW TO TAKE IT: Serving is 2 Vcaps. Take one or more servings per day as an antioxidant supplement. May be taken with food or on an empty stomach (this is food).
COMPLEMENTARY PRODUCTS: All antioxidants.
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This information has not been reviewed by the FDA or the company posting it. Information given here may vary from what is given on the product label because this page represents my understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
REFERENCES:
Bagchi D, Sen CK, Bagchi M, Atalay M. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Mosc). 2004 Jan;69(1):75-80, 1 p preceding 75. Review. PMID: 14972022
Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 2002 Jul 15;22(14):6114-20. PMID: 12122072
Huang D, Ou B, Prior RL. The Chemistry behind Antioxidant Capacity Assays. J Agric Food Chem. 2005 Mar 23;53(6):1841-1856. PMID: 15769103
Kay CD, Holub BJ. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 2002 Oct;88(4):389-98. PMID: 12323088
Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 2002 Dec 18;50(26):7731-7. PMID: 12475297
Prior RL, Cao G. Analysis of botanicals and dietary supplements for antioxidant capacity: a review. J AOAC Int. 2000 Jul-Aug;83(4):950-6. Review. PMID: 10995120
Prior RL, Cao G. In vivo total antioxidant capacity: comparison of different analytical methods. Free Radic Biol Med. 1999 Dec;27(11-12):1173-81. Review. PMID: 10641708
Prior RL, Hoang H, Gu L, Wu X, Bacchiocca M, Howard L, Hampsch-Woodill M, Huang D, Ou B, Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples. J Agric Food Chem. 2003 May 21;51(11):3273-9. PMID: 12744654
Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Radic Res. 2002 Feb;36(2):217-33. PMID: 11999391
Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berries. Free Radic Res. 2002 Sep;36(9):1023-31. PMID: 12448828
Sofic E, Rustembegovic A, Kroyer G, Cao G. Serum antioxidant capacity in neurological, psychiatric, renal diseases and cardiomyopathy. J Neural Transm. 2002 May;109(5-6):711-9. PMID: 12111462
Stintzing FC, Stintzing AS, Carle R, Frei B, Wrolstad RE. Color and antioxidant properties of cyanidin-based anthocyanin pigments. J Agric Food Chem. 2002 Oct 9;50(21):6172-81. PMID: 12358498
Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37. PMID: 15186133
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Enzogenol® Pine Bark Extract Fact Sheet
Date:
December 07, 2005 05:30 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Enzogenol® Pine Bark Extract Fact Sheet
Enzogenol® Pine Bark Extract Fact Sheet
Neil E. Levin, CCN, DANLA 4/14/05LIKELY USERS: Those seeking antioxidant protection; People trying to defeat the effects of aging KEY INGREDIENTS: Enzogenol® from New Zealand Pine Tree bark (Pinus radiata) Rutin (200 mg) and Grape Seed Extract (50 mg)
MAIN PRODUCT FEATURES: Enzogenol® is a powerful formulation of antioxidant bioflavonoids extracted from the bark of the New Zealand Pine (Pinus radiata) that is comparable to flavonoid formulations of other pine bark products. The flavonoids found in Enzogenol have been shown in clinical and non-clinical studies to support cardiovascular health and to protect cells and tissues from the damaging effects of oxidative stress. NOW® Enzogenol® also contains Rutin and Grape Seed Extract for their synergistic antioxidant benefits.
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: Enzogenol® is a powerful and highly effective formulation of antioxidants extracted from fresh New Zealand pine bark – one of the most comprehensive complexes of natural antioxidants. A breakthrough in processing technology combines all of these antioxidants in an Enzogenol® capsule in exactly the same ratios as are present in the tree's bark. What's more, the revolutionary pure-water extraction process doesn't use toxic solvents like traditional extraction processes do.
SERVING SIZE & HOW TO TAKE IT: One to four capsules a day as an antioxidant dietary supplement.
COMPLEMENTARY PRODUCTS: Other antioxidants including Vitamin C, VitaBerry Plus+TM, Alpha Lipoic Acid, NAC, etc.
CAUTIONS: There are no specific cautions with this product.
GENERAL CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is given on the product label because it represents my own understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
REFERENCES:
Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993 Oct 23;342(8878):1007-11. PMID: 8105262 Keli SO, Hertog MG, Feskens EJ, Kromhout D. Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study. Arch Intern Med. 1996 Mar 25;156(6):637-42. PMID: 8629875
Ames, BN, Shigenaga, MK, Hagen, TM (1993). Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA 90, 7915-7922
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Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
Date:
December 07, 2005 12:16 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05
LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue
KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients
MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.
Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.
Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas. Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body. NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator). Schisandra protects liver cells from toxins and may help to regenerate damaged cells. Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.
OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.
AMOUNT TO USE: Three or more capsules a day, preferably with meals.
COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.
AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)
CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
REFERENCES:
1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
2. Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil 1989;130:2723–7 [in Hungarian].
3. Muzes G, Deak G, Lang I, et al. Effect of silymarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind protocol.) Orv Hetil 1990:131:863–6 [in Hungarian].
4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871–9.
5. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999, 1179–80.
6. Rodriguez-Moreno F, Gonzalez-Reimers E, Santolaria-Fernandez F, et al. Zinc, copper, manganese, and iron in chronic alcoholic liver disease. Alcohol 1997;14:39–44.
7. Gibbs K, Walshe JM. Studies with radioactive copper (64 Cu and 67 Cu); the incorporation of radioactive copper into caeruloplasmin in Wilson’s disease and in primary biliary cirrhosis. Clin Sci 1971;41:189–202.
8. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999:1179–80.
9. Halsted CH. Alcohol: medical and nutritional effects. In Ziegler EE, Filer LJ (eds). Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, DC, 1996, 553.
10. Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2:1153–5.
11. Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicentre, double-blind study. Liver 1986;6:35–44.
12. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992. (Astragalus)
13. Hobbs, C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
14. Harada T, Kanetaka T, Suzuki H, Suzuki K. Therapeutic effect of LEM (extract of cultured Lentinus edodes mycelia) against HBeAg-positive chronic hepatitis B. Gastroenterol Int 1988;1(suppl 1):abstract 719. 15. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. Apr1998;3(2):114-27.
16. Montanini S, et al. Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients. Arzneimittelforschung. Dec1999;49(12):1044-7.
17. Buckley NA, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759-67. 18. Girardi G, Elias MM. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology. Apr1991;67(2):155-64.
19. Berkson MB. Alpha-Lipoic Acid (Thioctic Acid): My Experience With This Outstanding Therapeutic Agent. Journal of Orthomolecular Medicine. 1998;13(1):44-48.
20. Breithaupt-Grogler K, et al. Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. Eur J Pharm Sci. Apr1999;8(1):57-65.
21. Gebhardt R. Antioxidative and Protective Properties of Extracts from Leaves of the Artichoke (Cynara scolymus L.) Against Hydroperoxide-induced Oxidative Stress in Cultured Rat Hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
22. Adzet T, et al. Hepatoprotective Activity of Polyphenolic Compounds From Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes. J Nat Prod. Jul1987;50(4):612-17.
23. Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
24. Khadzhai I, et al. Effect of Artichoke Extracts on the Liver. Farmakol Toksikol. Nov1971;34(6):685-87.
25. Newall CA, et al. Herbal Medicine: A Guide for Health-Care Professionals. Cambridge: Pharmaceutical Press; 1996:36-37.
27. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
28. Bradley PR, ed. British Herbal Compendium. Vol.1. Bournemouth: British Herbal Medicine Association;1992:73-74.
29. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
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Grape Seed Extract - to fight prostate cancer...
Date:
October 10, 2005 10:37 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Grape Seed Extract - to fight prostate cancer...
Grape Seed Extract – contains proanthocyanidins, potent antioxidants that may lower the risk of cancer. In a recent study, Grape Seed Extract was used to inhibit cell growth in human cancerous prostate cells. The results suggest that grape seed antioxidant proanthocyanidins may exert a strong anticarcinogenic effect against prostate cancer by inhibiting abnormal cell growth and promoting tumor cell death.
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10 key nutrients and herbal extracts provide Prostate Support
Date:
October 04, 2005 10:54 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: 10 key nutrients and herbal extracts provide Prostate Support
The prevention of prostate cancer has been shown to be related to dietary intakes of some key nutrients, and several herbal extracts also can strongly influence prostate problems. It is important that herbal extracts and nutrients have the highest quality available and meet European pharmaceutical standards.
We looked hard and selected the following 10 items based on the following criteria:
1. Boron
2. Daidzein
3. Grape Seed Extract
4. Green Tea
5. Lycopene
6. Vitamin E
7. Selenium
8. Kohki Leaf
9. Pygeum Africanum
10. Nettle Root
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NEW PRODUCT ANNOUNCEMENT
Date:
July 05, 2005 06:29 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: NEW PRODUCT ANNOUNCEMENT
The Most Comprehensive Antioxidant Formula Available!
Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
Vitamin C (as ascorbic acid & ascorbyl palmitate) 1,000 mg
Vitamin E (as d-alpha tocopheryl) 400 IU
Riboflavin (vitamin B-2) 25 mg
Zinc (as monomethionine [OptiZinc®]) 15 mg
Selenium (as L-selenomethionine [SelenoPure™] 200 mcg
& sodium selenite)
Manganese (as manganese succinate) 10 mg
gamma-Vitamin E Complex 500 mg
Turmeric Rhizome Extract 95% 300 mg
alpha-Lipoic Acid & 210 mg
R-Lipoic Acid
N-Acetyl Cysteine 200 mg
Wheat Sprouts 150 mg
Quercetin 100 mg
Amla Fruit (Phyllanthus emblica) 100 mg
Grape Seed Extract 100 mg
(Proanthodyn™)
Green Tea Extract 100 mg
(95% polyphenols, 35% EGCG) Hawthorn Berry Extract (4:1) 100 mg
Mega H- Microcluster™ 100 mg
Silica Hydride Powder
Rosemary Leaf Extract 100 mg
(20% diterpenes)
Ginger Root 100 mg
Ginger Root Ext. (5% gingerols) 80 mg
SOD 80 mg (superoxide dismutase [GliSODin®])
Milk Thistle Seed Extract 80 mg
Yielding 66 mg Silymarin
Pomegranate Seed Extract 60 mg
(40% elagitannins)
Pomegranate Seed Extract 60 mg
(40% elagitannins) Red Raspberry Leaf Extract 50 mg
(40% elagitannins)
Blueberry Leaf Extract 50 mg
(20% chlorogenic acid)
L-Carnosine 50 mg
Ginkgo Biloba Leaf 24% 40 mg
(50:1 Extract)
Coenzyme Q10 30 mg
L-Glutathione 25 mg
Total Resveratrols (from 20 mg
Polygonum cuspidatum Extract)
Bilberry Fruit 20 mg
Std. Ext. (37% anthocyanosides)
Tocotrienol Complex 20 mg
(Tocomax®)
Myricetin 20 mg
DMAE (as bitartrate) 20 mg
Lycopene 3 mg
Lutein (FloraGLO®) 3 mg
Astaxanthin 1 mg
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Antioxidants
Date:
June 29, 2005 05:27 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Antioxidants
Antioxidants By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Antioxidants. A term we hear often, but do we really pay attention to the enormous role these substances play in our systems? And what are they exactly anyhow? Where do they come from and how do they work?
Antioxidants are a group of naturally occurring vitamins, minerals and enzymes found in plant foods. These vital substances help to protect our cells from free radicals, the culprits responsible for causing damage to our bodies very quickly.
Free radicals are groups of unstable atoms looking to obtain electrons in order to become stable themselves. They can pull electrons off cell membranes, causing the cell membranes to have free radical activity as well. This unleashes a vicious cycle of cell destruction, known as a “free radical cascade.” Free radical damage is linked to a plethora of diseases. Luckily there are literally thousands of antioxidants to help us win the “free radical battle”.
Antioxidants can be differentiated by their colors. Those of a red, orange or yellowish color fall into the group known as carotenoids, while those with a blue, purple, black color are from the phenolic family. Of course, there are also some yellow green phenolics too, like the polyphenols from Green Tea.
The carotenoid group of antioxidants are fat-soluble and therefore offer protection for the fat containing parts of the body. This is especially useful in protecting our lipid containing cell membranes. These carotenoids hang out in our membranes, thereby protecting them from free radical damage. What’s even more important is the ability of carotenoids to enhance the activity of other fat-soluble antioxidants such as vitamins A, E and Co Q-10. Some of the best carotenoid sources are lycopene, curcumin and lutein.
Lycopene, a red carotenoid derived from tomatoes, has been shown to contain strong protection capabilities against free radical damage. Curcumin, a yellow carotenoid from turmeric, displays a more protective antioxidant activity than that of Vitamin E or Vitamin A in protecting DNA breakdown (by free oxygen). It also serves as a potent anti-inflammatory agent. Lutein, another carotenoid antioxidant, is a primary component of the retina and macula areas of the eye. Lutein’s antioxidant properties may help protect the macula from light induced free radicals. Evidence shows it may help reduce the risk of age related macular degeneration as well.
The phenolic groups are the water-soluble antioxidants. This group protects the blood, lymph and other bodily fluids, as well as the organs containing those fluids. Some of the best phenolic antioxidants are those found in Green Tea, particularly a group known as catechins. Catechins have proven to have immune- enhancing benefits. Another family of important phenolic antioxidants are those called anthocyanins. These too have proven to act to protect the immune system. Finally, we can’t forget one of the best-known water-soluble antioxidants: Vitamin C !
The need for antioxidants is widespread. We normally think of smokers as the primary group who would most benefit from antioxidants, but the truth is that anyone under stress is a prime candidate for taking antioxidants. In addition, anyone who carries a strenuous physical or mental work load or who exercises often needs the protection of antioxidants, since free radical levels are increased by an active metabolism. And, of course, those individuals who don’t consume enough fruits and vegetables in their diet should also consider using a well-rounded antioxidant formula.
Nature’s Answer offers an outstanding selection of antioxidant formulas available in liquid and/or capsule form. These include Lycopene and Green Tea Extracts (liquid, softgel and vegetarian capsule), Bio-Flavonoids & Rose Hips (low organic alcohol liquid herbal extract) and Grape Seed Extract (vegetarian capsule). For a well-balanced potent antioxidant blend, try Antioxidant Supreme™, a standardized herbal extract formula containing the best of the carotenoid and phenolic antioxidants in one convenient vegetarian capsule. This formula, in particular, provides concentrated natural sources of antioxidants for “supreme” overall protection.
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Life Force - The Energy Activator
Date:
June 29, 2005 10:35 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Life Force - The Energy Activator
Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100%
We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating.
Bio-Align™ Yourself with Life Force
LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.
Get Ahead with Activated Energy and a Healthy Metabolism
Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.
LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.
Protect Your Heart and Circulatory System
The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.
Skin and Musculoskeletal Support
LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.
Brain and Nerves Nutrition
The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more Grape Seed Extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.
Immune Defense
LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.
Powerful Liver Support
Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.
Complete Antioxidant Defense
Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.
Cutting-Edge Vision Nutrition
The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.
Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle
LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.
Support Healthy Fat and Protein Consumption with Life Force
Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.
Complete Energizing Nutrition
LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!
References
Guyton, A. 1991. Textbook of Medical Physiology, Eighth Ed. W.B. Saunders Co., Philadelphia, PA. Halliwell, B. and Gutteridge, J. 1995. Free Radicals in Biology and Medicine. Clarendon Press, Oxford. Linder, M. 1991. Nutritional Biochemistry and Metabolism, Second Ed. Appleton and Lange, Norwalk, CT. Mathews, C. and van Holde, K.E. 1990. Biochemistry. The Benjamin Cummings Publishing Co., Inc. Shils, M. and Young, V. 1980. Modern Nutrition in Health and Disease, Sixth Ed. Lea & Febiger, Philadelphia, PA.
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Anti-Aging Nutrients
Date:
June 18, 2005 09:07 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Anti-Aging Nutrients
Anti-Aging Nutrients by Edward C. Wallace, DC, ND Energy Times, February 3, 2000
What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful, easy feeling.
How Do We Age?
Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.
The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.
Programmed Cell Theory
In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.
Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.
Free Radical/Oxidative Stress Theory
The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents.
Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.
DNA Repair Theory
Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.
What Can We Do?
The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.
In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."
Antioxidant Protection
Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.
Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.
In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.
Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.
Nutrition Deficiencies
A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).
When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).
A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.
Longevity Diets
A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460).
Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers (Epidemiology 3[5], 1992: 389-391).
Staying Alive
Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.
Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).
In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.
Longevity and Exercise
Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.
Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.
The Treadmill of Life
The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying (JAMA 273 [14], April 12, 1995: 1093-1098).
Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.
Longevity Supplementation
Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.
Toning Down Enzymes
Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).
In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.
The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).
Vitamins E & C
A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.
Chronological Age Vs.Biological Age
Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems.
In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.
Similar Relationship
A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less.
And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.
The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).
Carotenoids
When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.
Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119[1], Jan. 1989: 112-115).
Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.
Flavonoids
Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.
Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and Grape Seed Extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).
Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.
Amino Acid Health
Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.
Attitude & Behavior
Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).
In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).
Longevity at Last
While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of longer life. And by staying healthier, your old age will be more enjoyable, too.
--
Vitanet ®
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=377)
Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...
Date:
June 13, 2005 10:31 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...
Botanical Arsenal by Fred Thomas Energy Times, May 3, 1999
The complexities surrounding the various types of cancer stem from the variety of ways in which these diseases can wreak their havoc. Luckily, the equally complex world of plants contains novel compounds that can help our bodies fight off cancer's deadly progress.
Research Expands
Research into these botanical compounds is mushrooming. An example: The mighty maitake, a fungus with flair, alternately known as the king (it can grow as large as a basketball, worth its weight in silver to the ancient Japanese); the prince; the Hen of the Woods (it sticks out of from trees when it grows in the wild); and the dancing mushroom to those who leaped for joy when they found one growing in its native northeastern Japan.
Researchers today dub it with a new moniker: Herbal Heavyweight.
Mushroom with Potential
The maitake, with such other medicinal mushrooms as shiitake and reishi, historically has been eaten to promote general well-being and vitality. In the modern lab, however, scientists focus on the potent immune enhancing powers of maitake, which spotlight its cancer fighting potential.
Twenty years ago, maitake, Grifola frondosa, was an obscure, largely unavailable mushroom. A series of significant Japanese studies then catapulted it into prominence-and popularity.
Maitake Magic
Hiroaki Nanba, PhD, of the department of immunology at Kobe Women's College of Pharmacy on Kobe, Japan, and a leading international researcher on maitake, conducted the preliminary tests on the mushroom, demonstrating that it stimulates immune function and inhibits tumor growth.
In 1986, Dr. Nanba fed powdered maitake to mice injected with tumor cells; 86.3% displayed inhibited tumor growth.
Dr. Nanba and his colleagues went on to run additional mouse tests, finally reporting that this potent mushroom "directly activates various effector cells (macrophages, natural killer cells, killer T-cells, etc.) to attack tumor cells."
From then, maitake mushrooms were headed to fame as cancer ninjas.
Stoking The Immune Engine
Like other mushrooms, maitake is rich in complex polysaccharides, immunomodulators that successive tests after Dr. Nanba's have shown to be effective in cancer and AIDS treatment.
The polysaccharides in maitake have a unique structure, rendering them some of the most powerful to be studied (Chem Pharm Bull 1987:35:1162-8).
What makes maitake a particularly hot property is beta-D-glucan, its primary polysaccharide. Studies show that the body absorbs it readily, at which point it effectively stimulates interleukin-1, natural killer cells and macrophages, anti-tumor warriors that battle solid cancers (Chemotherapy 1990;38:790-6; also International Conference on AIDS, Amsterdam, 1992).
Effective And Safe
In addition to lab tests, trials on people have shown that maitake may offer powerful therapy against liver and stomach cancer (studies in China), breast and colon cancer (US research) and Kaposi's Sarcoma, the virulent cancer attacking AIDS sufferers.
Importantly, studies show that no side effects or interactions accompany maitake's efficacy.
Maitake fortunately has won the interest and enthusiasm of the scientific community. Currently, researchers at the Cancer Treatment Centers of America, headed by Denis Miller, MD, are completing an exhaustive test of the anticancer and immunostimulatory actions of maitake on folks with advanced colorectal cancer. These investigators hypothesize that the polysaccharide beta-glucans derived from the fruitbody of maitake fight tumors and boost immune function. "Though it cannot be said that maitake ...[is] the cancer cure," said Dr. Nanba in his closing remarks at the Adjuvant Nutrition in Cancer Treatment Symposium in Tampa, Florida, in October 1995, "one can safely say that they do maintain the quality of life of patients and improve the immune system, resulting in the possible remission of cancer cells with no side effects."
More Bodily Benefits
Maitake maven Dr. Nanba also has tested-with strongly positive results-the effect of maitake on blood glucose, insulin and triglycerides in mice, whose levels of all three substances declined when they were fed the mushroom (H. Nanba working paper, Anti-Diabetic Activity by Maitake Mushroom, 1994).
With colleagues, Dr. Nanba showed that maitake lowered blood pressure in hypertensive rats (Chem. Phann. Bu//36:1000-1006,1988). Other studies suggest it may accelerate weight loss.
This admirable adaptogen (meaning it helps the body adapt to stress and normalize its functions) is water soluble and may be eaten in food or taken as a supplement. Vitamin C is believed to intensify maitake's beta-glucans and enhance their absorption.
Tea Time
It's not just what you eat that may help protect against cancer, but what you drink as well. Research from China and Japan, where tea is the everyday drink and rates of several cancers like breast and prostate are lower, may persuade you to turn over a new leaf in your own beverage choice. One of the first studies to spark interest in tea came from Shanghai (Journal of the National Cancer Institute, June 1, 1994), where people who drank two to three cups a day were found to have about a 60% reduction in the risk of cancer of the esophagus. The reason: tea leaves contain compounds called polyphenols, potent antioxidants.
In fact, in tests at the University of Kansas, three of these, known as catechins, far outshone the common antioxidant vitamins C and E. Clinical trials are just starting, but early results are encouraging. A team of Chinese scientists reported that in a third of people with precancerous mouth sores who drank three cups of a mixture of green and black tea the lesions shrank significantly.
Researchers at the Saitama Cancer Center in Japan found that green tea seems to improve the prognosis of breast cancer. They followed a group of women with early-stage tumors for seven years. Those who drank more than five cups of green tea a day were only half as likely to suffer a recurrence as patients who consumed fewer than four cups a day.
Lung Help
And at the University of Indiana, toxicologist James Klaunig found that the lungs of cigarette smokers who drank the equivalent of six cups of tea a day suffered 40 to 50 percent less damage from the toxins in smoke, potentially lowering their risk of lung cancer and other pulmonary problems. Simultaneously, research from Purdue University suggests tea's cancer-discouraging powers go beyond being an antioxidant. Scientists Dorothy and D. James Morre showed that a tea catechin dubbed EGCG inhibits a growth-promoting enzyme on the surface of many cancer cells-happily without affecting normal cells. And researchers at the Ohio State University College of Medicine found that EGCG counteracted another enzyme, urokinase, that helps cancer cells spread. To top it off, Mayo Clinic scientists recently showed that EGCG prompted prostate cancer cells to commit suicide (Cancer Letters, Aug. 14, 1998).
Tea Research
So far, most tea research has focused on green tea, and investigators agree it's more potent than the black tea most Americans favor. But because both kinds come from the same plant, Camellia sinensis (it's the processing that makes the difference as black tea is fermented, green tea isn't) both contain cancer-fighting polyphenols, just in different quantities. As long as the tea you drink (even decaffeinated) is fresh brewed, it's likely to provide some benefit; powdered and prepared teas probably don't. And adding milk may dilute the effect.
Astragalus Against Tumors
Astragalus, an herb commonly used in Asia to boost stamina, has impressed western doctors for its potential for helping people cope with chemotherapy. As John Diamon, MD, W. Lee Cowden, MD and Burton Goldberg point out in the Definitive Guide to Cancer (Future Medicine), "Astragalus appears to protect the liver against the harmful toxic effects of chemotherapy and may be effective in treating terminally ill liver cancer patients." (They cite a study in the Jrnl of Ethnopharmacology 1990, 30:145-149.) In addition, they point out, research in Japan supports using a ginseng-astragalus combination to improve the function of natural killer (NK) cells which can boost immunity (Japanese Jrnl of Allergy, 37:2, 1998, 107-114).
Other studies confirm astragalus' potential in fighting off cancer. Research at the General Hospital of PLA, Beijing, showed that flavonoids (pigments) in astragalus could help protect cell membranes from oxidative damage caused by ultraviolet exposure (Chung Kuo Chung Yao Tsa Chih, 21(12):746-8; 1996 Dec).
A study of laboratory animals at Cunma University in Maebashi, Japan, found that Astragalus could help preserve immune function against the harmful side effects of chemotherapy (Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 15(2):101-3, 1995 Feb).
Garlic Benefits
Like a flame attracting moths, garlic bulbs have irresistibly drawn the attention of medical researchers. A study at Aarhus University, Denmark, found that skin cells in laboratory dishes treated with garlic supplements lived longer, healthier lives than untreated cells (Jrnl Ethnopharm, 1994. 43:125-133).
Meanwhile, a long list of research demonstrates that garlic's phytochemicals may fight tumors and reduce the carcinogenicity of the pollutants and chemicals that assault us daily. A study in China reported in the American Journal of Chinese Medicine showed that garlic helped slow tumors in lab animals (1983, 11:69-73). Another study in the Journal of Nutrition found that compounds in garlic could "suppress the growth of human colon tumor cells" (126, 1355-1361).
Added to those benefits, Robert A. Nagourney, MD, reports in the Journal of Medicinal Food (1:1, 1998, 13-28), garlic may "modify the carcinogenicity of foodstuffs." In other words, studies show that garlic can make chemicals in foods like pork less likely to cause your cells to become cancerous. (Ind J Physiol Pharmacol, 39:347-353).
DNA Protection
DNA, the stuff that genes are made of, face constant threats from free radicals, caustic molecules that can alter cellular structure and possibly cause genetic mutations that lead to cancer. But research into what are called oligomeric proanthocyanidins (OPC), flavonoids (pigments) derived from fruits vegetables, Grape Seed Extract and the bark of maritime pine trees shows that OPC may be able to shield DNA from injury.
In particular, studies of a Grape Seed Extract called Activin have demonstrated this substance can help liver cell DNA escape a destructive process called peroxidation (FASEB, 11:3, 2/28/97).
In these experiments, Activin demonstrated the ability to inhibit the growth of tumor cells as well as slow the replication enzymes of HIV viruses. This protective ability proved to be more potent than that of vitamin C, beta carotene and vitamin E.
Future Promise
What does the future promise to reveal? Scientists believe that many unexamined plants probably contain undiscovered phytochemicals that hold great potential for helping us fight the cancer epidemic.
Certainly, if the next few years produce as many results as the past decade, the next millennium will witness a long line of cancer-prevention discoveries. Before long, you should be able to take advantage of these potent substances.
As you gulp your garlic, tip your tea cup, mull your maitake, acquire Activin and await your astragalus, you may meditate on what may soon be added to our growing anti-cancer arsenal. Undoubtedly, scientists with a botanical bent will be uncovering more coveted anti-cancer secrets before too long.
--
Vitanet ®
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=326)
Nutrients for Longevity
Date:
June 10, 2005 09:59 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Nutrients for Longevity
Nutrients for Longevity by Edward C. Wallace, ND, DC Energy Times, September 1, 1999
What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful easy feeling.
How Do We Age
Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.
The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.
Programmed Cell Theory
In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.
Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.
Free Radical/Oxidative Stress Theory
The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain.
On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution.
Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.
DNA Repair Theory
Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.
What Can We Do
The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.
In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."
Antioxidant Protection
Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.
Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.)
Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.
In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725).
Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.
Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.
Nutrition Deficiencies
A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).
When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).
A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.
Longevity Diets
A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460)
Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers. (Epidemiology 3[5], 1992: 389-391).
Staying Alive
Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.
Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects. (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).
In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.
Longevity and Exercise:
Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.
Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184).
In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.
The Treadmill of Life
The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying. (JAMA 273 [14], April 12, 1995: 1093-1098).
Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.
Longevity Supplementation
Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging.
Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.
Toning Down Enzymes
Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls.
In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).
In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.
The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).
Vitamins E & C
A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.
Chronological Age Vs. Biological Age
Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.
Similar Relationship
A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.
The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).
Carotenoids
When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.
Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119(1), Jan. 1989: 112-115).
Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.
Flavonoids
Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs.
For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.
Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and Grape Seed Extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).
Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.
Amino Acid Health
Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68).
As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.
Attitude & Behavior
Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit.
In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).
In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).
Longevity at Last
While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of living longer. An added benefit: By staying healthier, your old age won't only be longer, it will be more enjoyable, too.
And, who knows, if you hang around long enough, taking your nutrients and getting a comfortable amount of consistent exercise, while meditating and refusing to succumb to stress, that magic bullet that will keep you alive for centuries may be discovered. Some day a new antioxidant or other substance may finally prove to provide the elusive fountain of youth. Stay tuned.
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Vitanet ®
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Immunity - The Big Picture
Date:
June 10, 2005 09:51 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Immunity - The Big Picture
Immunity: The Big Picture by Brian Amherst Energy Times, August 3, 1999
Your body wants to be well. Outfitted with a battalion of defenses for strategic deployment, your immune system explodes with resistant force at the first sign of infective invasion.
Think of the time a tiny splinter embedded itself in your thumb. By bedtime, the spot rose and reddened; by morning, white blood cells had launched their campaign, building a hot, throbbing fortification. By day's end, the bit of wood was propelled to the surface and ejected by the immune system warriors. Once again, a foreign assailant was summarily ousted.
The Protective Force
The immune system is a dazzlingly complex mechanism charged with guarding against infection, colds, flu and cancer. Laced with networks of couriers and transmitters, backed up by intricate fail safe devices and reinforced by memory units, immunity constantly adapts to highly specific and evolving needs.
"Supporting the immune system is critical to good health. Conversely, good health is critical to supporting the immune system." So write naturopathic doctors Michael T. Murray and Joseph E. Pizzorno in their Encyclopedia of Natural Medicine (Prima).
Maintaining the immune system requires a comprehensive program of wholesome diet, resilient attitude, fitness enhancing activity and nutrients keyed to the clear and specific needs of this energetic machine.
The all-star lineup for immune sustenance: a high-potency multiple vitamin/mineral formula, vitamins C and A, bioflavonoids, isoflavones, zinc and selenium, antioxidants like ActiVin (Grape Seed Extract) and pycnogenol (French maritime pine bark), as well as the botanicals echinacea and astragalus.
But optimal partnering with your immune system also benefits from understanding its workings.
The Battlefronts
The immune system wages war on the organ, tissue and cellular fronts. It encompasses the lymphatic vessels and organs (lymph nodes, thymus, spleen and tonsils), white blood cells, specialized cells in particular tissues and customized chemicals.
Lymph, a milky fluid consisting of water protein and immune cells, is the essence of the immune system. Powered by muscle movement (an important reason why exercise boosts immunity), the lymphatic system collects and transports lymph to the lymph nodes. These nodes contain certain immune cells and filter out invading antigens, as well as produce antibodies, before siphoning the lymph out into the bloodstream.
If you've ever had "swollen glands," that means your lymph nodes have been in overdrive.
Macrophages are the immune cells that filter lymph, consuming bacteria and cellular debris while protecting the lymph system from invasion and damage.
Gland Tidings
Two organs dominate immune function: n The thymus. The most influential, critical gland of the immune system, located just below the thyroid gland and above the heart; produces T lymphocytes, white blood cells responsible for cell-mediated immunity not controlled by antibodies. This immune response is tailored to specific antigens and is vital to resisting infection from mold-like bacteria including yeast, fungi, parasites and such viruses as Epstein-Barr, herpes simplex and hepatitis. It also protects against cancer, allergies and autoimmune disorders like rheumatoid arthritis. n The spleen. The largest mass (about seven ounces) of lymphatic tissue in the body, located in the upper left abdomen behind the lower ribs; it produces white blood cells, which engulf and destroy bacteria and cellular debris; recycles material from worn out red blood cells and platelets; produces immune system enhancing compounds, including the proteins tufsin and splenopentin, and spleen extracts.
The White Blood Cell Album
Although white blood cells (WBCs) are uniformly accountable for protecting the body against bacteria, viruses, fungi and parasites, the different types of WBCs vary considerably in form and function. n Neutrophils phagocytize, that is, eat, viruses, bacteria and old or dead cells. They don't need any biochemical messengers for activation and their effectiveness is wide-ranging.
In Monocytes collect cellular trash after infections and can trigger immune responses; eosinophils can eliminate foreign particles and, with basophils, are involved in immune response.
In Lymphocytes include varieties of T cells, which work with other white blood cells or attack and destroy foreign tissue, cancer cells or virus-infected cells; B cells that produce antibodies that bind to bacteria, viruses or tumors; and natural killer cells (NKCs) that destroy cancerous or virally-infected cells.
(Based on information in the Encyclopedia of Natural Medicine; The Road to Immunity: How to Survive and Thrive in a Toxic World (Pocket Books) by Kenneth Bock, MD, and Nellie Sabin; and the Johns Hopkins Family Health Book (Harper Resource).
Keep the System Sound
Your immunity mechanism calls for special care and support. The dilemma: How to develop a balanced system of complementary and alternative therapies to build and sustain powerhouse immunity? "There is no question that, in terms of immune system response, certain supplements can reduce infections, asthma, autoimmune disease and risk factors for cancer," says Samuel D. Benjamin, MD, former project director of the Arizona Center for Health and Medicine and an ardent advocate for complementary medicine.
"But you must always be sure to maintain the mind-body-spirit link," he told Energy Times. "For the mind, it could be exercise, yoga or meditation. Evidence shows improved immune system responses from these therapies. And in any case, you never read in the headlines that somebody has been admitted to the emergency room overdosing on meditation.
"Intentionality also is an important part of the mind link: believing you are going to fare well. For your spirit, you must ask yourself such questions as, Do I feel connected to others?
"For the body, a daily multivitamin and mineral supplement. Much depends on your community: I live on Long Island, where there is a high incidence of breast cancer, so I would recommend green tea and isoflavones from soy products for women."
Dr. Benjamin stresses moderation in the use of immune-intensifying supplements, among which he cites mixed carotenoids, zinc and vitamin E.
The Soy Solution
Scientists who took the cue from the apparent link between high-soy Asian diets and low cancer incidence have developed a compelling case for soy as an immune-supportive anticancer agent.
In a study conducted by the University of Southern California at Norris and published in the March 4, 1998 Journal of the National Cancer Institute, researchers reported that genistein, an active component of soy products, short-circuits the ability of tumor cells to elude destruction by the immune system due to an excess of defensive stress proteins.
Genistein seems to make cancer cells vulnerable to the immune response. Researchers at Wake Forest University told participants at the January 1999 meeting of the American Association for the Advancement of Science that dietary or supplemental soy fed to monkeys counteracted cell proliferation that is a cancer precursor.
That Championship C
Probably the most widely recognized immune accelerator is vitamin C, an honored warrior against scurvy and, in 1970, again celebrated by Linus Pauling for its preventive powers over the common cold.
Immune cells are known to accumulate and retain high levels of vitamin C. Researchers at Memorial Sloan-Kettering Cancer Center in New York now understand how that happens: Proteins called growth factors (which control growth and production of immune cells) also increase those cells' ability to take up vitamin C.
These researchers, reporting in the April 1998 issue of the journal Blood, explain that the additional glucose that the growth factors pump into immune cells (for enhanced energy), plus extra vitamin C, intensify immune response.
And folks with higher levels of vitamin C in their blood serum experience less cell damage from free radicals that leads to cancer, heart and pulmonary disease and other chronic conditions.
Scientists at the University of Buffalo (addressing the June 13, 1997 meeting of the Society for Epidemiologic Research) deduced from studying population groups that high levels of vitamin C are associated with low oxidative stress and lower risk of cell damage.
From A to Zinc
In Kids with neuroblastoma, a malignant tumor of embryonic nerve cells and the third most common form of childhood cancer, experienced significantly improved survival rates when their therapy included high doses of retinoic acid, a derivative of vitamin A, according to researchers at the University of California, San Francisco, and Childrens Hospital Los Angeles, who reported to the American Society for Clinical Oncology on May 18, 1998.
In Colostrum, the pre-milk liquid produced by mammals during the first 24 to 48 hours after birth, took the spotlight recently as a supplement imbued with multiple immune factors and natural antibiotics that augment body's immune response. A 1992 study showed that bovine colostrum might be able to reduce and prevente infections in immune deficient folks, especially those with AIDS.
In University of Pittsburgh Cancer Institute researchers found for the first time (on laboratory animals) that vitamin D appreciably inhibits widespread prostate cancer by binding to cancer cells and triggering cell death or their transformation to benign cells.
In Vitamin E exerts formidable immune-enhancing influence on both antibody and cell-mediated immunity. One fundamental study in the Journal of the American Medical Association (245, 1981: 53-58) established conclusively that vitamin E deficiency results in significant impairment of immune function. Later studies demonstrated that it reduces prostate cancer by up to one-third.
In Coenzyme A, described as a metabolic enzyme, takes part in starting numerous body processes that provide energy for the immune system. If you ever run short of this enzyme, fat processing within your body would grind to a halt.
in Researchers looking at a substance with the tongue twisting name 3-acetyl-7-oxo-Dehydroepiandro-sterone, believe it aids immunity by quelling stress hormones.
in Mushrooms contain natural substances called polysaccharides, believed to enhance immunity. In particular, maitake mushroom, which conveys the immune booster beta-D-glucans, is reputed to help fight infections and drop blood pressure.
in Men and women taking selenium supplements for 10 years had 41% less total cancer than those taking a dummy, according to a January 1997 study by Cornell University and the University of Arizona. Other studies have shown it to reduce the risk for colon cancer by about 60%. n Zinc may provide immediate protection against the all too common cold. Scientists at the University of Florida were the first to apply genetic fingerprinting methods like those used in criminal and paternity investigations to understand how nutrients directly affect human immune cells.
The study, in the April 1998 Journal of Nutrition, demonstrates that zinc signals cells to make the protein metallothionein, which protects against infections, toxins and other stressors.
Phytochemicals a la Carte
Researchers extol the powers of phytochemicals in fruits and vegetables available in dietary or supplement form as immune-igniting antioxidants. These compounds neutralize free radicals that oxidize cellular membranes, rendering them vulnerable to cancer.The Strang Cancer Prevention Center, an affiliate of New York Presbyterian Hospital, offers a menu of the top antioxidant phytochemicals. The center's director, Mitchell L. Gaynor, MD, is coauthor (with Jerry Hickey, RPh) of Dr. Gaynor's Cancer Prevention Program (Kensington): n Carotenoids, including beta-carotene from veggies and lycopene (the substance that lends the tomato is ruddy complexion), fight free radicals.
n Isoflavones from soy, fight angiogenesis, the process by which new blood vessels form to supply nutrients to cancerous growths. n Sulforaphane in broccoli, kale and cabbage activates anticancer enzymes.
n Omega-3 fatty acids in cold water fish block the synthesis of prostaglandins, natural compounds in the body that promote tumor growth.
n Ginger contains antioxidant compounds, each more potent than vitamin E. Recent studies on mice show ginger can prevent skin tumors. n Rosemary contains carnosol which deactivates carcinogens and helps limit the effects of prostaglandins.
Sometimes the world can look like a dangerous place, especially when you're sick and tired much of the time. But in the search for immunity, menus of health help like this ensure that no matter what your immunity needs, a boost can be yours with the proper nutrient selection.
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Vitanet ®
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Improove Memory ...
Date:
June 09, 2005 05:49 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Improove Memory ...
Mesmerizing Memory by Cal Orey Energy Times, January 1, 1999
In the 60s, the same rock 'n' rollers who belted out "One pill makes you larger and one pill makes you small," often espoused the belief that certain pills could expand the mind. While counter-culture pill purveyors were pilloried for their pill-popping claims, 90s nutritional research has uncovered a stash of supplements that may amplify mental improvement.
Like a blues singer bending a high note, researchers are now humming with dramatic assertions that certain nutritional supplements can sustain and enhance concentration and memory function. For instance, studies reveal possible benefits for cognitive powers from vitamin C, magnesium and Ginkgo biloba. A recent report in the Journal of the American Medical Association (JAMA 278:1327-1332) said that an extract of Ginkgo biloba "can stabilize and, in some cases, improve the cognitive function and social behavior of demented patients."
A researcher in the Proceedings of the National Academy of Sciences noted that a daily dose of vitamin E may "help protect the brain and its memories from the ravages of time." And the beat goes on: other evidence indicates that zinc, iron and boron may pump up short-term memory attention span and cut the time it takes to perform mental tasks.
Neuronutrients
Neuronutrients-mentally helpful vitamins, minerals, fatty acids, amino acids and trace elements-offer an exciting key to keeping mental functions from succumbing to the degenerations of aging and disease. According to Dharma Singh Khalsa, MD, author of Brain Longevity (Warner Books) and an energetic campaigner for mental fitness through nutrition and exercise, vitamin E "can not only prevent deterioration of the brain, but actually reverse an important element of deterioration." Dr. Khalsa describes vitamin E as one of the most potent antioxidants, a fighter of the electrically charged free radicals that attack and break down cell membranes and nerve endings.
Lester Packer, PhD, professor of molecular and cell biology at UC Berkeley, told a joint 1996 United Nations-World Health Organization conference on Aging that "there is a growing body of evidence indicating that the free radical theory of aging and aging-related disease is valid," and that dietary and supplemental antioxidants can help fight illness and mental deterioration.
Vitamin E and other memory aids are believed to protect brain chemicals called neurotransmitters, "the ferrymen of the brain's communication system," that influence concentration and memory. Experts say that sustaining the level of these nerve chemicals in the brain can potentially improve all mental processes.
Brain Well-Being
"Your brain is intricately bound up with your physical state of well-being and is, therefore, vulnerable to any kind of physical abuse, especially that of chemical or substance abuse," report Thomas H. Crook III, PhD, and Brenda Adderly, MHA, co-authors of The Memory Cure (Pocket Books).
Too much alcohol, for example, commonly causes progressive mental decline, according to Secrets of the Superyoung (Villard) by David Weeks and Jamie James. The authors also point out that "the memory tends to worsen noticeably after 15 years of alcohol drinking, and much sooner in people who go on massive binges."
"The effects of cigarette smoke are subtler because the poisonous effects of carbon monoxide in each puff are temporarily offset by the alerting effects of the nicotine," they add. Can't remember the name of that singer cavorting in a music video? Tests have shown that smokers are worse at connecting peoples' names to their faces than nonsmokers.
Cognition Ignition
A first step in beginning your brain-boosting regimen consists of intensified intellectual activity, insists Rebecca Rupp, writer of Committed to Memory: How We Remember and Why We Forget (Crown): n Keep working: The mental challenges and social interactions of a job prevents lapses in the brain's synapses.
n Learn something new: A second language, musical instrument, or unique puzzles and games keep neurons working like new.
n Turn off the TV: Read. Studies show that passively watching TV requires less concentration than eating cereal. Mental rejuvenation also requires physical activity. Exercise increases oxygen flow to the brain, which supports memory, concentration and cognition. One study has shown that exercise significantly brightened the moods of middle-aged and older women, regardless of whether they were pre- or post-menopausal, with or without hormone replacement therapy.
Supplemental Brain Help
As you provide for your physical and mental vitality through healthy exercise and diet, you can augment your regimens with other supplements that research has shown to boost brain power.
Antioxidants, including the previously mentioned vitamin E (You haven't forgotten vitamin E already, have you?), provide crucial help for vigorous cerebral function. The free radicals created by tobacco smoke, air pollution, ultraviolet light and certain carcinogenic chemicals deconstruct cell membranes and may foster microscopic brain cell havoc. Antioxidant enzymes convert free radicals to more neutral, benign substances and nutritional antioxidants can neutralize free radicals by linking up with them.
Vitamin C, a brainy antioxidant all star, performs so well that, according to Dr. Khalsa, its levels in the brain are almost 15 times higher than in other parts of the body. This nutrient, he asserts, aids mental and physical longevity. In a UCLA study, people who ingested at least 300 mg of vitamin C daily lived more than six years longer than those who ingested less.
Mental Fat
As a brain protector, selenium ranks high. Your brain consists of about 60% fat and selenium is a master at restricting detrimental fat oxidation. At the same time, zinc takes part in antioxidant processes that quell free radicals and strengthens neuronal cell membranes, protecting nerves from damage.
Added to this mix, magnesium also scavenges free-radicals, according to Dr. Khalsa. Plus, experts recommend Grape Seed Extract (phytochemicals that protect a wide range of cellular structures) to safeguard nerve cells and mental capacity.
B Vitamins for the Mind
John W. Rowe, MD, president of Mount Sinai Hospital and School of Medicine in New York and author of Successful Aging (Pantheon) states that "there is a significant relationship between blood levels of folic acid and vitamins B12 and cognitive decline." In other words, these vitamins seem to be necessary to eliminate a protein called homocysteine, which has been implicated in the development of coronary heart disease and cognitive problems. (Support for Dr. Rowe's conclusion appeared in the American Journal for Clinical Nutrition 63-306.)
Iron Mind
Iron also may strengthen memory. Since iron is involved in distributing oxygen to brain cells (and every other cell in the body), when you lack this mineral you may find it hard to concentrate. In the early 1990s, Harold Sandstead, MD, professor of preventive medicine at the University of Texas, discovered that women whose diets lack zinc and iron experienced more difficulties on standard exams than women with an adequate dietary supply. In his study of women aged 18 to 40, Sandstead found that giving these women more zinc and iron raised their scores on memory tests and average of 20%.
Boron plays a crucial part in mental function. Scientists at the USDA's Human Nutrition Research Center have linked boron deficiencies to chronic lethargy and fatigue. In brain studies, they found that the electrical activity of the gray matter in the boron deficient indicated increased drowsiness and mental sluggishness.
Huperzine Boost
Borrowed from Chinese folk medicine, Huperzine A (HupA) recently has attracted attention from researchers who credit it with enhancing cognitive function and helping folks suffering from disease-related dementia. HupA is an extract of the club moss Huperzia serrata and has been used for centuries in China to treat fever, inflammation and, most recently, dementia. Dr. Alan Kozikowski, professor of chemistry in the neurology department at Georgetown University's Drug Discovery Program, a researcher who first synthesized HupA and studied it extensively, reported in the Journal of the American Medical Association (JAMA, 277 (10):776-March 1997), that HupA is safe, having been used to treat 100,000 people in China.
HupA basically protects the brain from free radical damage (due to low levels of antioxidant defenses) and maintains or enhances crucial neurotransmitter action. More specifically, HupA helps reduce the breakdown of acetylcholine, the vital neurotransmitter, and makes this substance more bioavailable. In addition, HupA helps make choline accessible to the brain for the synthesis of acetylcholine, according to a study in Neuropharmacology (30, 1991: 763-768).
Normally, the brain manufactures sufficient levels of the chemical phosphatidylserine, a lecithin-derivative that helps boost neurotransmitter release, but deficiencies of vitamin B12 and folic acid, or of essential fatty acids, may retard that production. Low levels of phosphatidylserine in the brain are related to impaired mental function and depression in the elderly. Scientists reporting in Aging (5, 1993; 123-33) describe "good results" using phosphatidylserine in the treatment of age-related cognitive ills.
Ginkgo Brain Power
Researchers also have demonstrated that Ginkgo biloba extract (GBE) increases brain function mostly by boosting acetylcholine receptors and the transmission of nerve impulses, with no significant adverse reactions. GBE is effective not only for folks with Alzheimer's; it also helps when mental function is impaired by vascular deficiencies or depression. Keep in mind that experts believe that GBE requires about 12 weeks of supplementation to reach optimal effectiveness.
Another ingredient in what seems like an alphabet-soup of brain nourishment is DHA (docosahexaenoic acid), an omega-3 fat essential for normal brain function. Researchers met recently at The New York Hospital-Cornell Medical Center's Nutrition Information Center to discuss "Keeping Your Brain in Shape: New Insights into DHA." Their findings revealed links between low levels of DHA and Alzheimer's, depression, memory loss, attention-deficit/hyperactivity disorder (ADHD) and certain behavioral traits including aggression and hostility.
Mostly Fat
Since so much of the brain is fat, material like DHA forms the building block of brain tissue and the primary structural fatty acid in its gray matter. Although it is critical for mental and visual well being, the average American's consumption of DHA has declined since we're eating less of DHA's dietary sources: animal organ meats and eggs.
Researchers from the National Institutes of Health point out, however, that fish is an excellent dietary source of DHA. In their studies, they discovered that depression rates in Japan and Taiwan, where fish ranks a top spot on the menu, are significantly lower than in North America and Europe.
DHA also is crucial to the neurological development of children, according to findings published in Pediatrics (vol. 101, no. 1, January 1998). Researchers suggest that DHA-rich breast milk should be the model for infant formulas that enhance babies' neurological development. Scientists also have correlated some behavioral problems in children-ADHD, for example-to DHA deficiencies.
If you are a vegetarian, or have other cause for concern about a potential lack of DHA in your diet, you can rely on dietary supplementation of DHA. Bruce J. Holub, PhD, of the University of Guelph in Canada provided vegetarians in his research project with DHA supplements over a 42-day period and substantially increased their DHA blood levels.
The bottom line to enhanced mental performance is to take a balanced approach, says Robert Snider, MD, who specializes in preventive medicine in Massena, New York. "Maintaining brain power includes exercise, stress reduction and good nutrition." The message to keep in mind: Don't lose your nutritional balance or you could lose a piece of your peace of mind.
Recommended Reading: & Brain Builders (Reward Books, 1995), by Richard Leviton.
Brain Longevity (Warner Books, 1997), by Dharma Singh Khalsa, MD.
Omega 3 Oils to Improve Mental Health, Fight Degenerative Diseases and Extend Life (Avery, 1996), by Donald Rudin, MD, and Clara Felix.
Successful Aging (Pantheon, 1998), by John W. Rowe, MD, and Robert L. Kahn, PhD.
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NutraSpray in Melatonin, Proanthodyn, and St. John's wort
Date:
June 03, 2005 05:35 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: NutraSpray in Melatonin, Proanthodyn, and St. John's wort
NUTRASPRAY represents a quantum leap in the evolution of supplementation, an elegant combination of convenience, fast action, bioavailability, and sustained release delivery. Source Naturals has long championed the sublingual delivery system, and our Super Sublingual™ is the latest step in the science of nutrition. A quick spritz of NUTRASPRAY under the tongue delivers thousands of microscopic lipid spheres, each full of nutrients. These lipospheres are readily absorbed and retained by the mucosal tissue of the mouth. Here they release their nutrients quickly, but steadily, into the bloodstream – creating a Super Sublingual, the most bioavailable supplement today.
Nutrient delivery systems include tablets, capsules, softgels, and liquid extracts. Their purpose is to ensure the cells in your body get the nutrients they need from the supplements you take. Sublinguals bypass the digestive system – and its potentially destructive juices – by dissolving under the tongue to be directly absorbed into the bloodstream. Tests show that the NUTRASPRAY liposome sublingual delivery system is more efficient than traditional sublinguals.
The First Timed Release Sublingual
Due to the multi-layered structure of the tiny lipospheres, nutrients are gradually released for extended periods of time, maintaining optimal dosage throughout the day or night. This combined with a faster onset of the active ingredients – usually within 15 minutes – makes NUTRASPRAY the most bioavailable delivery system for nutritional supplements today, and the first truly timed release sublingual.
Unparalleled Convenience
NUTRASPRAY incorporates a simple, non-aerosol spray pump that’s easily carried in purse or pocket. Its modern functional design is a perfect complement to today’s active lifestyle. It’s easy to regulate nutrient amount, because the convenient pump delivers a specific amount of nutrient-rich liposomes with every spray, and each 2 fl. oz. recyclable plastic bottle can deliver 80 full sprays. Stevia is added as an ingredient in each NUTRASPRAY product.
Advanced Research
The lipid micro-encapsulation process is based on years of research in liposomal technology. The result is NUTRASPRAY, a proprietary system to deliver nutrients in the most efficient manner. This sublingual oral spray is a liquid suspension of liposomes, which are nutrients encased in very complex microscopic lipid spheres, 1/50th the diameter of a human hair. A highly purified natural lecithin forms the membrane of these lipid spheres, which are able to move easily through the lipid environment surrounding the capillaries in the mouth. Lipospheres then gradually release their nutrients into bloodstream.
Nutrients That Go To Your Head
The Source Naturals NUTRASPRAY line includes natural supplements that are particularly well-suited to this Super Sublingual delivery system, such as Melatonin, Ginkgo Biloba, Coenzyme Q10, Grape Seed extract, and Kava. That’s because these nutrients need to reach the brain for maximum benefit. Also, they’re usually taken for reasons that the fast-acting quality of NUTRASPRAY satisfies. Another unique reason NUTRASPRAY is so bioavailable is that its nutrients bypass the liver on their first pass through the circulatory system. This ensures the nutrient is available to the brain for maximum potency. Source Naturals NUTRASPRAY MELATONIN delivers 1.5 mg of the finest quality Melatonin with each full spray, easily allowing customers to control their intake. Melatonin is ideally suited to the fast-acting nature of NUTRASPRAY, which maintains a more balanced release of Melatonin throughout the night. Source Naturals NutraSpray GINKGO-24™ provides 60 mg of Ginkgo Biloba per full spray. This makes Ginkgo’s beneficial constituents readily available to the capillaries in the blood-brain barrier, facilitating oxygen flow to the brain. CoQ10 is fat soluble; therefore encapsulating it in a lipid is the perfect way to ensure its bioavailability. Each full spray of Source Naturals NUTRASPRAY™ COQ10 yields 30 mg of CoQ10. Furthermore, this popular metabolic enhancer is very experiential with the NUTRASPRAY delivery system. NUTRASPRAY Grape Seed Extract delivers 50 mg per spray of proanthocyanidins standardized to 95%. These highly bioavailable flavonoids are able to cross the blood-brain barrier, offering potent antioxidant protection to precious neurons. NUTRASPRAY KAVA KAVA is a potent extract standardized to a potent 40% kavalactones, the active constituents of this traditional root from the Polynesian cultures of the South Pacific. The relaxing action of Kava works through the brain’s limbic system, which regulates emotions related to survival issues, including the “fight or flight” response. Each spray yields 60 mg of Kava. Look for other fine products soon to come out in the Source Naturals line of NUTRASPRAYS. Source Naturals built its reputation on bringing the latest nutritional research to market, using the finest ingredients in substantial quantities – for an experience of wellness and vitality you can feel. Source Naturals NUTRASPRAY is a major step toward empowering people to achieve optimal health in a challenging world.
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Heart Science - A Five-Tiered Approach to Heart Health ...
Date:
June 02, 2005 12:07 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Heart Science - A Five-Tiered Approach to Heart Health ...
Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.
Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health
Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
1) generating energy,
2) decreasing harmful homocysteine levels,
3) fighting oxidized cholesterol,
4) maintaining the heart’s electrical rhythm, and
5) protecting artery and capillary linings.
Energy Generators for An Energetic Organ
Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.
There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.
CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10
Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.
Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21
HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.
Homocysteine Regulators
B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.
The Dangers of Oxidized LDL Cholesterol
While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.
When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.
The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.
Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.
Cholesterol Fighters
Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:
The Regulating Trio
Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.
Artery Lining Protectors
Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6
Capillary Strengtheners
Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.
Heart Smarts
The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.
Source Naturals HEART SCIENCE™
The Five Tiered Approach to Heart Health
Six tablets contain:
Vitamins and Minerals %USRDA
Pro-Vit A (Beta Carotene) 45,000 IU 900%
Vit B1 (Thiamine) 50 mg 3333%
Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
Vit B6 (Pyridoxine HCl) 25 mg 1250%
Coenzyme B6 (Pyridoxal-5-Phosphate)
25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
Vit B12 (Cyanocobalamin) 500 mcg 8333%
Folic Acid 800 mcg 200%
Vit C (Magnesium Ascorbate) 1500 mg 2500%
Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
Copper (Sebacate) 750 mcg 37.5%
Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
Potassium (Citrate) 99 mg *
Selenium (L-Selenomethionine) 200 mcg *
Silicon (From 400 mg of Horsetail Extract) 13mg *
* U.S. RDA not established.
Other Ingredients and Herbs
Coenzyme Q10 (Ubiquinone) 60 mg
L-Carnitine (L-Tartrate) 500 mg
Hawthorn Berry Extract 400 mg
Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from Grape Seed Extract) 100 mg
L-Proline 500 mg
L-Lysine (HCl) 500 mg
NAG™ (N-Acetyl Glucosamine) 500 mg
Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
Taurine (Magnesium Taurinate) 500 mg
Horsetail Extract (Yielding 31 mg of Silica) 400 mg
Inositol (Hexanicotinate) 50 mg
Reference:
1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.
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VitaNet ® Staff
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HEART RESPONSE - Comprehensive Support for a Healthy Heart!
Date:
June 02, 2005 11:51 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: HEART RESPONSE - Comprehensive Support for a Healthy Heart!
Today’s modern lifestyle, filled with stress, pollution, overprocessed and fatty foods, and lack of exercise, places great strains on the cardiovascular system. Source Naturals HEART RESPONSE is a broad-range formula that supports cardiovascular health, especially heart muscle contraction, healthy circulation and the generation of cellular energy.
HEART RESPONSE features clinical potencies of the renowned heart botanical, hawthorn, and significant amounts of the energy nutrients, coenzyme Q10 and carnitine, along with additional nutrients and herbs. Each daily use supplies 600 mg of hawthorn, the same amount used in recent research.
Supports Heart Health
HEART RESPONSE was formulated to include key nutrients and herbs known to support the cardiovascular system.
Hawthorn: Hawthorn, a rich source of flavonoids and procyanidins, has been used traditionally all over the world as a strengthening circulatory and heart tonic.
Modern research has documented that hawthorn increases coronary blood flow and strengthens the contraction of heart muscle. Hawthorn is also an antioxidant, which scavenges and neutralizes destructive free radicals. It is only when cholesterol is oxidized that it impacts the integrity of arteries.
Coenzyme Q10: HEART RESPONSE supplies 60 mg daily of CoQ10, a key enzyme in the Electron Transport Chain, the pathway that generates 90% of the ATP “energy currency” needed by the body. Heart muscle requires huge amounts of energy to perform efficiently—it beats more than 100,000 times each day, pumping more than 1,000 gallons of blood through the body. The heart utilizes ATP as an energy source for muscular contraction. CoQ10 also is a fat-soluble antioxidant.
L-Carnitine: Carnitine is an amino acid-derived substance that supports heart muscle metabolism. Carnitine is needed to carry long chain fatty acids into the cell mitochondria, where they undergo oxidation to generate energy. The heart utilizes fatty acids as a preferred energy source for its metabolism.
HEART RESPONSE delivers 300 mg per day of carntine. Taurine and Magnesium: Magnesium and taurine work closely together in the body to help maintain the normal electrical rhythm of the heart. Taurine comprises more than 50% of the free amino acid pool in our hearts, and has many electrophysiological effects on cardiac muscle cells. Alterations in magnesium levels can have profound effects on the heart. Magnesium is involved in autonomic control of the heart through several mechanisms. Bromelain: Bromelain is an enzyme mixture prepared from pineapple stems. Pineapple has been used for its health benefits for more than 500 years.
Grape Seed Extract: Grape seed is a source of procyanidins. These plant constituents are strong antioxidants that inhibit lipid peroxidation and scavenge free radicals. In vitro studies have demonstrated that procyanidins support the integrity of connective tissue. Garlic: The use of garlic for its health benefits predates written history. Garlic’s volatile oil includes sulfur-containing compounds such as allicin, which are considered to be important biological constituents.
Selenium: Selenium is an essential trace mineral that is necessary for the activity of the important antioxidant glutathione. Antioxidants are crucial for protecting cholesterol from oxidation, which in turn helps to maintain healthy blood vessels. B-Vitamins: Preventing an undesirable buildup of homocysteine levels may help support the integrity of arteries. Vitamins B-6, B-12 and folic acid are critical to the regulation of homocysteine levels.
You can count on Source Naturals’ expert formulators to bring you a product based on the most up-to-date nutritional research. HEART RESPONSE combines traditional botanicals and cutting-edge nutrients, scientifically formulated to deal with many aspects of cardiovascular health. It is available in bottles of 30, 60 and 90 tablets.
References
Heinicke, R.M. et al. 1972. Effect of bromelain (ananase) … Experientia. 28(7):844-5. Karpati, G. et al. 1975. The syndrome of carnitine deficiency. Neurology. 25:16-24. Schmidt, U. et al. 1994. Efficacy of the Hawthorn (Cratageus) preparation L1 132 … Phytomedicine. 1:17-24. Upton, R. ed. Hawthorn Leaf with Flower – Cratageus spp. Santa Cruz: American Herbal Pharmacopoeia, 1999.
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GlucosaMend™ Tissue/Joint Repair Complex
Date:
June 02, 2005 11:19 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: GlucosaMend™ Tissue/Joint Repair Complex
More than 40 million Americans experience joint discomfort. But exciting new research proves you can do something about it. Our health and well-being is inextricably linked to lifestyle choices: the right combination of exercise, weight training and supplementation can strengthen muscles and joint tissues to minimize stress and degradation. Targeted nutrition to the multiple body systems related to joint and connective tissue can help maintain flexibility and joint comfort. GLUCOSAMEND supports the musculoskeletal system with structural building blocks and tissue production cofactors, as well as aiding the body’s mechanisms for soothing relief and antioxidant defense.
Bio-Aligned Formula™ GLUCOSAMEND is uniquely effective because it is a Bio-Aligned Formula. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance.
Musculoskeletal System—Structural Building Blocks
Certain building blocks of joints and connective tissue can help maintain joint integrity and comfort. Glucosamine is a major constituent of glycosaminoglycans, which in turn form proteoglycans, molecules that hold and bind the water that lubricates joints, disperses stress and nourishes joint tissue. The amino acids proline and lysine are structural components of collagen and elastin, which give strength to connective tissue. GLUCOSAMEND contains glucosamine sulfate, N-acetyl glucosamine, proline and lysine.
Musculoskeletal System—Tissue Production Cofactors
Some micronutrients are necessary as cofactors in the production of connective tissue. For example, vitamin C and copper help form hydroxyproline and hydroxylysine, main constituents of collagen. A unique property of grape seed extract is its ability to form a bond between broken collagen fibers, helping to repair them and restore flexibility and strength to connective tissues and joints. GLUCOSAMEND provides vitamin C, zinc, manganese, copper, and grape seed extract to address these cofactors.
Soothing Relief Mechanisms
Some herbs and nutrients have the capacity to support the body’s natural mechanisms for increasing comfort. Boswellia, for example, is an herb with soothing properties, while vitamin B-6 helps to stabilize collagen and elastin. Additional herbs and nutrients, acting in conjunction with antioxidant protectors, support tissue comfort and health. GLUCOSAMEND contains Boswellia serrata, quercetin, copper, and vitamin B-6.
Antioxidant Defense
The health and integrity of joints and tissues—specifically of cell membranes— is supported by botanicals and nutrients that support the body’s natural antioxidant response. When tissues become damaged, the body mounts a repair process that ultimately generates free radicals. These free radicals can also break down healthy cells and tissues in the process, hence the need for antioxidants to neutralize and break the cycle. GLUCOSAMEND provides Grape Seed Extract, vitamin C, zinc, selenium, copper, quercetin to neutralize free radicals.
Lifestyle Tips for Healthy Joints: A Strategy for WellnessSM
Healthy lifestyle habits should be part of your individual strategy for joint wellness. Source Naturals believes in a holistic approach to living. Not only can supplements bring balances to your individual body systems but certain lifestyle choices can also bio-align your health. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, limit saturated fat and eliminate hydrogenated oils. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAME, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CHONDROITIN to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage.
Structural Building Blocks N-Acetyl Glucosamine, Glucosamine Sulfate, L-Lysine, L-Proline Tissue Production Cofactors Grape Seed, Copper, Manganese, Zinc, Vitamins A, B-6 and C, Niacinamide Soothing Relief Mechanisms Boswellia Serrata, Quercetin, Turmeric, Copper, Magnesium, Zinc, Vitamin C Antioxidant Defense Grape Seed, Quercetin, Manganese, Selenium, Zinc, Vitamins A, C and E
References
Bhavan’s, B. H. Selected Medicinal Plants of India (A Monograph of Identity, Safety, and Clinical Usage) Bombay: Chemexcil, 1992. Dore-Duffy, P., et al. (1990, Nov-Dec.). “Zinc profiles...” Clinical and Experimental Rheumatology 8.6: 541-46. Ellis, J. M. (1985, Winter). “Vitamin B6 deficiency and rheumatism.” Anabolism. Lakshmi, R., et al. (1991, Oct-Dec.). “Effect of riboflavin or pyridoxine deficiency on inflammatory response.” Indian Journal of Biochemistry and Biophysics 28.5-6: 481-84. Leibovitz, B., (1991). Nutrition Update 5.3: 5. Levine, M. (1986). “New concepts in the biology and biochemistry of ascorbic acid.” New England Journal of Medicine 314: 892-902. Pavelka, K, Gatterova, J., Olejarova, M, Machacek, S., Giacovelli, G., Rovati, L.C., (2002). “Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis: A 3-Year, Randomized, Placebo-Controlled, Double-Blind Study. Arch Intern Med, 2002 October 14; 162(18):2113-23. Roubenoff, R., et al. (1995, Jan.). “Abnormal vitamin B6 status...” Arthritis and Rheumatism 38.1: 105-9. Shampe, P., and R. Harvey. Lippincotts Illustrated Reviews: Biochemistry. Philadelphia: J. B. Lippincott Company, 1987. Tarp, U., et al. (1985). Scandanavian Journal of Rheumatology 14.2: 97-101. Volpi, N., (2002). “Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers,” 2002 Oct; 10(10):768.
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Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement
Date:
June 01, 2005 01:13 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement
What makes ÉLAN VITÀL unique is its unprecedented range of nutriments in high potencies and superior forms. Quite simply, it stands alone among multiples: a quantum leap beyond maintenance...into excellence. Not only does it offer unparalleled antioxidant nutrition and a full-spectrum of essential vitamins and minerals, ÉLAN VITÀL is also formulated with specific nutrients that support:
Today’s inflated levels of stress and pollution give rise to harmful free radicals – unpaired electrons that can damage living cells and compromise the proper function of tissues and organs. Antioxidants serve to protect the body by neutralizing free radicals; in fact, many scientists believe that high levels of antioxidants may prolong the effective working life span of the body’s cells. The primary strategy of ÉLAN VITÀL is to provide a wide range of antioxidants at exceptional levels, from both botanical and biochemical sources.
Plantioxidant Protection
ÉLAN VITÀL has the powerful advantage of Plantioxidants™, standardized botanical extracts with unparalleled free radical-scavenging properties. Plantioxidants have the unique quality of providing targeted protection because they tend to be attracted to different organs in the body. Grape Seed Extract is rich in potent proanthocyanidins, a special class of highly bioavailable, water-soluble bioflavonoids that have the unique ability to cross the blood-brain barrier where they support the health of brain cells. Proanthocyanidins have been shown to efficiently scavenge oxygen radicals, as well as optimize the transport of vitamin C. They also have an affinity for collagen and elastin, the structural proteins that are abundant in vessel linings and other connective tissue. ÉLAN VITÀL contains the most concentrated extract of Bilberry available, with at least 25% anthocyanosides – compounds which are similar to proanthocyanidins but with an unusually strong attraction to optical tissue. They have been shown to protect cellular integrity in the delicate structures of the eyes. Ginkgo biloba extract is a standardized concentration of prime quality ginkgo leaves, yielding 24% ginkgoflavoneglycosides. These active compounds are potent antioxidants that have been associated with superior oxygen transport throughout the body with a special affinity for brain capillaries. Silymarin is the name given to a complex of three bioflavonoid-like compounds — silybum, silycristin, and silymarin — extracted and concentrated from milk thistle seeds. Silymarin functions in the body as an antioxidant with a special attraction for the liver. It has been researched and used extensively in Europe, where it is prized for its unique ability to nourish the liver and support its natural regeneration process by speeding up DNA synthesis in liver cells. Quercetin is a bioflavonoid present in some foods, such as onions and blue-green algae. A cousin of rutin, quercetin has been shown to stabilize cell membranes and help prevent free radical damage to this vital but vulnerable part of cells. Bioflavonoids and related compounds do their best antioxidant work when in the presence of Vitamin C, the nutrient they are most often paired with in nature. The vitamin C provided in ÉLAN VITÀL is both water- and fat-soluble. This combination is crucial because the tissues and membranes richest in fatty acids are most at risk to free radical attack. Fat-soluble vitamin C in the form of ascorbyl palmitate has an affinity for these highly vulnerable structures.
Antioxidant Nutrients
ÉLAN VITÀL not only provides botanical defense plants to combat free radicals, but also contains tried-and-true antioxidant nutrients: Biochemicals known as vitamins, minerals, and amino acids work together for maximum protection to all the body’s cells. The amino acid, N-Acetyl Cysteine, is a powerful and highly versatile antioxidant that doubles as a precursor to glutathione and glutathione peroxidase, two of the most formidable cell-protective compounds manufactured by the body. Studies have shown that supplemental N-acetyl cysteine enhances internal levels of glutathione far better than supplements of glutathione itself. Methionine also contributes to the synthesis of glutathione, and is an efficient transporter of certain antioxidant minerals, magnifying their activity. Vitamin A is included in both its fat-soluble palmitate form and in its provitamin form, Beta Carotene. While preformed A has long been known to play a role in the body’s defenses, beta carotene itself has recently been shown to possess a powerful ability to scavenge free radicals and contribute to the youthful function of some tissues. Vitamin E is one of the most important antioxidant compounds in nature. It works to prevent harmful oxidation within each cell and is vital in the protection of red blood cells from free radical-induced rupture. Selenium is an extremely powerful antioxidant shown in studies to work synergistically with Vitamins A, C, and E. In combination with cysteine, selenium helps build the glutathione peroxidase molecule. ÉLAN VITÀL offers a 50/50 blend of the two most scientifically supported forms of selenium: L-selenomethionine and sodium selenite. In addition to being an antioxidant itself, Zinc works closely with fat-soluble vitamin A by facilitating its release from the liver to the rest of the body. In ÉLAN VITÀL, Zinc is synergistically bound to methionine for optimal bioavailability. Copper sebacate is a natural compound that can function as the copper-SOD antioxidant system in the body, one of the first lines of defense against free radical attack. Copper sebacate is a highly absorbable form that possesses significant free radical scavenging activity.
Supporting Structural Integrity
An important adjunct to antioxidant nutrition is the amino sugar N-Acetyl Glucosamine, or N-A-G™. Amino sugars are essential components of cell membranes and their surface structures, as well as of the “ground substance” that holds body tissues together. They are also a key constituent of the synovial fluid in the joints. Recent research has revealed that amino sugars play an important role in maintaining the integrity of the connective and structural tissues of the body, a property that complements perfectly the actions of antioxidants: where antioxidants may prevent damage from occurring, amino sugars may help the body repair and regenerate damaged tissue. N-A-G’s activity is supported in ÉLAN VITÀL by other nutrients helpful to structural tissue. The mineral Manganese is required for building amino sugars into mucopolysaccharides, the large molecules that make up the ground substance that holds cells together. Choline and Inositol are both components of phospholipids, principal constituents in cell membranes. Two B vitamins, Folic Acid and Vitamin B12, are important to cell regeneration and to the development of healthy red blood cells.
Enhanced Energy to Maximize Metabolism
ÉLAN VITÀL is a potent source of coenzymes, metalloenzymes, and metabolites involved in energy production in the body. There are two main energy production cycles in the cells: the glycolytic cycle and the Krebs’ cycle. Together, they generate about 90-95% of the body’s entire energy supply – using fats, sugars, and amino acids as fuel, with enzymes as facilitators. The enzymes which catalyze energy production function in combination with coenzymes made from vitamins such as B1, B2, B3, B5 and Biotin, plus metalloenzymes made from minerals, including Magnesium, Manganese, and Copper. Biotin, an often overlooked nutrient, may function to help the body maintain a youthful metabolism. The mineral Magnesium aids in energy production, not only by acting as a cofactor to some enzymes, but also as a stabilizer of ATP, the body’s primary energy molecule. Some of the key connecting enzymes in the energy production process require two additional non-vitamin coenzyme nutrients to maximally convert food into energy: Lipoic Acid and Coenzyme Q10. Lipoic acid helps convert the end-product of the glycolytic cycle, pyruvate, into acetyl-CoA, a principal fuel for the higher energy Krebs’ cycle. Coenzyme Q10. is the connecting link for three of the four main enzyme complexes in the Electron Transport System, an off-shoot of the Krebs’ cycle, where ATP molecules are “cashed in” for energy. The muscle-supporting electrolyte mineral Potassium is in the form of Alpha- Ketoglutarate, a critical Krebs’ cycle metabolite that has additional benefits. It has long been used to improve the efficiency of ammonia-clearance from the body, an indispensable function, as ammonia is both exceedingly harmful and constantly produced through the natural metabolism of proteins. Because alpha-ketoglutarate is an organic compound well-recognized by the cells, it is an excellent transporter of potassium into the cells. Succinic Acid, or succinate, is also a metabolite in the Krebs’ cycle. It not only boosts production of ATP energy potential, but also increases the muscle cells’ production of creatine phosphate, another high energy biochemical. Chromium is the essential mineral component of glucose tolerance factor, or GTF, which functions to help insulin (one of the two main blood sugar-controlling hormones in the body) draw sugar molecules from the bloodstream into the cells.
Smart Nutrients
ÉLAN VITÀL contains natural substances that sharpen performance beyond just the physical. N-Acetyl L-Tyrosine is a highly stable and absorbable form of the conditionally essential amino acid L-tyrosine, a precursor to the major excitatory neurotransmitters dopamine, norepinephrine, and epinephrine. DMAE is a precursor to one of the body’s main neurotransmitters, acetylcholine. From the Plantioxidants comes standardized Ginkgo biloba extract, whose compounds readily cross the blood-brain barrier where they support the integrity of the capillaries in the brain.
Guarding the Liver
ÉLAN VITÀL provides several nutrients which collectively support optimal liver function. This is an essential aspect of a multiple, because the liver is responsible for converting nutrients – from food as well as from supplements – into their usable forms. If liver function is compromised in any way, nutrient supplements may be rendered inert in the body. The liver is especially at risk because it must filter out ingested toxins and is continually exposed to chemicals that generate free radicals. N-Acetyl Cysteine and Silymarin have both demonstrated a strong affinity for the liver. Nacetyl cysteine contributes to increased levels of glutathione and glutathione peroxidase, both of which the liver uses in its natural cleansing function. Silymarin provides unparalleled support to the liver’s natural regeneration process. Because of its many vital functions, the liver uses as much as 12% of the body’s energy supply, even though it represents only 3% of body weight. The liver therefore uses a greater proportion of energy nutrients, especially Coenzyme Q10 and Lipoic Acid. Both are highly concentrated in the liver; and lipoic acid in particular has been researched and used heavily in Europe where it is prized for its special protective actions in the liver. Ascorbyl Palmitate is a fat-soluble form of Vitamin C, meaning it can provide antioxidant protection for fatty tissue. This is especially valuable to the liver, which tends to develop fatty streaks that are most vulnerable to damage. Vitamin E has been researched extensively for its antioxidant properties with regard to the liver.
The Multiple for the 21st Century
ÉLAN VITÀL is truly a one-of-a-kind multinutrient supplement: one that leaves no nutritional stone unturned. Based on the biochemical principles of nutrition and metabolism – in context of today’s challenges to our health – ÉLAN VITÀL approaches optimal nutrition from several directions...all leading to a lifetime of health and vitality.
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Bioflavonoid Complex - Botanical Antioxidant Protection
Date:
June 01, 2005 09:15 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Bioflavonoid Complex - Botanical Antioxidant Protection
Bioflavonoid Complex
The plant kingdom offers some of nature's most powerful antioxidants— biological molecules that scavenge and neutralize damaging free radicals. Source Naturals BIOFLAVONOID COMPLAEX ™ features outstanding plant antioxidants in a potent defense complex. Often referred to as "specialty bioflavonoids," these premium botanical protectors may have an affinity for specific organs and body systems. BIOFLAVONOID COMPLEX contains botanicals that support cardiovascular function, circulation, joint and connective tissue, vision, the liver, and the brain and nervous system.
Specialty Bioflavonoids
Bioflavonoids occur as pigments in plants, where they are found in close association with vitamin C. Together, bioflavonoids and C provide antioxidant protection, helping plants withstand harsh environmental conditions. BIOFLAVONOID COMPLEX features potent botanical extracts, many of them standardized to specific beneficial constituents. Included are bilberry, ginkgo biloba, grape seed, green tea, hawthorn berry, quercetin, and silymarin. The formula is enhanced by the addition of vitamin C as highly bioavailable magnesium ascorbate.
References
Armstrong, D., et al. (1984). Free Radicals in Molecular Biology, Aging, and Disease. Raven Press: NY Braquet, P. ed. (1988). Ginkgolides: Chemistry, Biology, Pharmacology, and Clinical Perspectives. J.R. Prous Science Pub: France. Busse, W.W., et al. (1984). J Aller and Clinic Immunol, 73:801-809. Hikino, et al. (1984). Planta Medica 50: 248-50. Meunier, M.T. et al. (1989). Plantes Med et Phytother, 23(4):267-274. Packer L. (1994) Ann. N.Y. Acad. Sci. 738: 257-264. Schmidt, U. et al. (1994). Phytomed 1: 17-24.
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Attentive Child - Enhances Mental Concentration ...
Date:
May 31, 2005 05:14 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Attentive Child - Enhances Mental Concentration ...
Most children are creative, energetic and spontaneous, but sometimes they don’t focus on requested activities. Sometimes kids find it difficult to apply themselves to the task at hand. Your child’s brain also may work differently than most people’s brains— just like the 5% of the population that is left-handed. Most people think an ultra-active child means an active brain, but active children may actually need a boost in brain metabolism. Source Naturals ATTENTIVE CHILD is a Bio-Aligned Formula™ designed to address the multiple systems that affect children’s ability to focus: neurotransmitters and brain metabolism, nerve cell communication, antioxidant defense, and essential fatty acid metabolism.
Comprehensive Brain Support
Parents are looking for a safe and natural product to support their children’s ability to focus. Source Naturals studied the research and created an experiential formula, based on the latest breakthroughs in cerebral and nervous system biochemistry. Each ingredient in ATTENTIVE CHILD plays a role in brain and nervous system structure or functioning, or is involved in important biochemical pathways. DMAE, a substance normally found in the brain, boosts brain metabolism and has been shown to enhance concentration. L-Aspartate is an amino acid neurotransmitter that stimulates brain activity. Research has shown that some ultra-active children may have special dietary needs for magnesium, zinc and DHA (docosahexaenoic acid). Magnesium is necessary for the transmission of nerve signals, and, along with zinc, for the processing of essential fatty acids into other vital biochemicals. DHA is an essential fatty acid that is very important for cerebral development and effective communication between nerve cells in the brain. Lecithin contains four phospholipids—fatty acid building-block molecules in nerve cell membranes. Phosphatidylserine, in particular, is vital in nerve cell communication and the electrical activity of the brain. Grape Seed Extract is a plant-derived antioxidant that protects the integrity of fatty acids in nerve cell membranes.
ATTENTIVE DHA™ in Tiny Kid Caps™
The ATTENTIVE CHILD formula can be supplemented with additional DHA. ATTENTIVE DHA Kid Caps are available in easy-to-swallow, small oval softgels, each containing 100 mg of DHA. For children who can’t swallow caps, simply pierce the gel and mix the oil with food. Sweeteners with Low Impact on Blood Sugar The delicious sweetand- tart taste in ATTENTIVE CHILD wafers comes from natural flavors, specially manufactured without sugar for Source Naturals. Unless specified, most flavors in other products contain maltodextrin, a sugar with a high glycemic index. The ATTENTIVE CHILD wafer itself is sweetened with crystalline fructose (natural fruit sugar) and xylitol (a naturally occurring sweetening agent found in many fruits and vegetables). These select natural sweeteners have a very low glycemic index—so ATTENTIVE CHILD will taste great to your child, but have little effect on blood sugar levels. We recommend carefully reviewing the labels of other products. They may contain honey, glucose, sucrose, maltodextrin, and maltose—all of which have moderate-tohigh glycemic indexes. In addition, maple sugar, molasses, malt syrup, rice syrup, and beet sugar contain varying amounts of high-glycemic-index sugars, which can set off blood sugar fluctuations that may affect concentration. Beware of children’s nutritional bars designed to enhance focus and concentration. Most have over 20 grams of sugar per bar. In contrast, each serving of ATTENTIVE CHILD contains only two grams of crystalline fructose, which has little effect on blood sugar.
Glycemic Index of Various Sweeteners
The glycemic index is a ranking of foods based on their immediate effect on blood glucose levels. It measures how much your blood glucose increases over a period of two or three hours after intake. The higher the glycemic index (GI), the greater the fluctuations in blood sugar. Sweetener Glycemic Index†
Xylitol* 7.0
Crystalline Fructose* 23.0
Organic Agave Nectar†† 10.0
High Fructose Corn Syrup 62.3
Sucrose 65.0
Honey 73.0
Glucose 97.0
Maltodextrin 105.0
Maltose 105.0
*sweeteners used in ATTENTIVE CHILD ™ †based on rate of 100 for glucose ††for information, see website www.wcommerce.com
Lifestyle Strategies for Your Child
You can help your child concentrate on schoolwork, chores and other challenges. Start with ATTENTIVE CHILD and ATTENTIVE DHA, and then incorporate a healthy lifestyle and nutrition routine.
Physical Health
Have your child’s overall health checked by a welltrained holistic health care professional, such as a naturopathic physician. It is particularly important to examine the functioning of your child’s thyroid gland (the master regulator of the body’s metabolism, which influences mood and energy level), and blood sugar metabolism (the brain depends on a steady supply of glucose to function properly, particularly when you are trying to concentrate).
Nutritional Health: Feeding the Brain
Help your child maintain a steady supply of energy and brain fuel by providing a balanced diet. Small, frequent meals are preferable since they dispense a steady level of glucose to the brain. Include foods high in the amino acid tyrosine, a precursor to neurotransmitters that support an alert state. It is found in protein foods, such as meat, poultry, beans, tofu, lentils and seafood. Also include complex carbohydrates such as whole grains, fruits and vegetables, which are metabolized slowly and yield a steady supply of glucose. The simple sugars found in candy, cookies, sodas and other processed foods can lead to a rapid rise in blood sugar levels, followed by an abrupt decline, and should be discouraged. It is important to include essential fatty acids, especially omega-3 fatty acids, which are abundant in the brain and essential for its development and normal functioning. Supplement with ATTENTIVE DHA, and encourage your child to eat cold-water fish, such as salmon. Avoid the hydrogenated fats found in processed foods and margarine, as well as chemicals and food additives. A nutrition program consisting of fresh, unprocessed natural foods is the healthiest choice for everyone.
Lifestyle Health
Some experts believe extended time watching TV and playing video games does not support optimal health or school performance. EEG studies have shown that these activities decrease brain activity rather than activating the brain. Encourage your child to spend time in outdoor physical recreation and in creative, challenging activities.
Supplement with ATTENTIVE CHILD and ATTENTIVE DHA
ATTENTIVE CHILD is available in bottles of 30 & 60 chewable wafers. ATTENTIVE DHA Kid Caps (algal-source Neuromins®) are available in 30- & 60-softgel bottles. References Amen, D. Windows into the....Mind. Fairfield, CA: MindWorks Press, 1997. Foster-Powell, K. & Miller, J.B. 1995, International tables of glycemic index. Am J Clin Nutr. 62:871S-93S. Natah, S.S. et al. 1997. Metabolic response to lactitol and xylitol in healthy men. Am J Clin Nutr. Apr; 65(4):947-50. Schmidt, Michael. Smart Fats. Berkeley: Frog, Ltd., 1997. Sears, William. Boston: Little, Brown & Co., 1998.
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