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	Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?	Darrell Miller	12/7/23
	Acai may offer prebiotic benefits throughout the GI tract, researchers find	Darrell Miller	10/31/17
	Turmeric Extract May Help Overcome Chemotherapy Resistance	Darrell Miller	9/29/17
	9 Health Benefits of Switching to Brown Rice	Darrell Miller	8/12/17
	5 Reasons Why Your Eyebrows Are Thinning and How to Stop it	Darrell Miller	7/20/17
	High-Fiber Diet Keeps Intestinal Walls Intact	Darrell Miller	4/3/17
	Soluble corn fiber can improve women's bone health	Darrell Miller	1/14/17
	Alleviating Blood Sugar Levels with Chromium Picolinate	Darrell Miller	11/27/13
	Can Too Much Fiber Block Mineral Absorption ?	Darrell Miller	10/12/11
	What can you get from Too Much Fiber?	Darrell Miller	10/11/11
	Turmeric, Curcumin, And Good Health	Darrell Miller	11/11/10
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	Polyphenols is an Antioxidant	Darrell Miller	10/13/08
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Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be Inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

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Date: October 31, 2017 10:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Acai may offer prebiotic benefits throughout the GI tract, researchers find

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Date: September 29, 2017 10:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Turmeric Extract May Help Overcome Chemotherapy Resistance

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Date: August 12, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 9 Health Benefits of Switching to Brown Rice

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Date: July 20, 2017 07:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 5 Reasons Why Your Eyebrows Are Thinning and How to Stop it

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Date: April 03, 2017 06:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: High-Fiber Diet Keeps Intestinal Walls Intact

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Date: January 14, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Soluble corn fiber can improve women's bone health

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Date: November 27, 2013 08:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Alleviating Blood Sugar Levels with Chromium Picolinate

What is Chromium Picolinate

Chromium picolinate is among the essential trace minerals that have received a lot of attention as dietary supplements. While it is know to be inhibit blood sugar levels, there are recurring debates that remain unsettled. However, there are recent studies that consistently revealed the augmenting effect of chromium to the actions of the hormone insulin. That then suggests the intake of the said mineral as it seconds the claims of it being an effective solution to control blood sugar or glucose levels of people intolerant to carbohydrates.

Benefits of Chromium Picolinate

Keeping your blood sugar at a normal level does everything. May it be to gain or lose weight, reduce fat, curbing craving pangs and lowering appetites, as well as warding off numerous chronic diseases such as diaebetes and heart attack, a normal blood sugar level does it all. For that matter, chromium is really of the essence. And here are some of its major health benefits. 

Blood Sugar Control

Cholesterol Level Control

Curbs Down Carb Cravings

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Date: October 12, 2011 01:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Too Much Fiber Block Mineral Absorption ?

Fiber Overview

Fiber has always been known to be a helpful substance in many ways related to digestion and our bowel movements. In terms of how much is too much though we would need to look at first what fiber can do and how it works in the colon to have a broader point of view and to take all aspects into account before determining if too much fiber can cause health issues and specifically in this case, can cause a form of blockade for mineral absorption.

What is Fiber and what does it do?

Fiber, simply put is a substance that is found primarily in the outer layers of plants. Fiber is considered a carbohydrate and a special one at that because of its ability to stay intact even after passing through our digestive system unlike other carbohydrates that gets broken down by food and used for energy. For better understanding let’s talk more about its importance. For one, it has the ability to influence our digestive process in so many ways. It’s most evident importance and function is how it is able to regulate digestion and virtually slow the process down.

With this, it is able to allow us to feel full longer which will cause less appetite therefore affecting weight and in turn overall health. With the same process it slows glucose processing as well which will aid in sugar levels and also helps nourish the colon’s lining to keep it from damage and maintain its health. However in a more practical sense, it aids in our digestion because of its sponge like qualities. So if coupled with a good amount of water in the stomach it will aid and ease the stool and help bowel movements along. This is more known to many as a cleansing process which brings me back to the question, can it be too much and affect mineral absorption?

Can too much affect absorption?

A simple and most straight forward answer is “yes”. Yes it can, absolutely it can and “how?” you ask. As discussed above, one of the ways that fiber functions is aid with the cleansing process and the same sponge like qualities are the primary reason why it can affect mineral absorption in the colon. The reason why fiber is effective for cleansing is because it absorbs bacteria and any other toxin or harmful substances in the colon and flushes it out therefore promoting good health however it can’t filter through its absorption process and select only those toxins, rather it absorbs both good and bad substances, the good in this case being the minerals.

So before it can be absorbed by the body, fiber already caused it to be excreted. But this does not mean you stop taking fiber, remember the key words here are “too much” and all we need to do to avoid any mineral deficiency is to follow the right amount, we can check with our doctor for best advice but most experts believe getting somewhere around 30 – 35g maybe too much but then again most Americans does not even come close to that with their regular diets.

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Date: October 11, 2011 12:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What can you get from Too Much Fiber?

Dietary fibers are plant food particles which cannot be digested and absorbed by the body. Fiber only adds roughage or bulk to the stool making it easier to pass out. It cannot be broken down into simpler compounds then absorbed by the body for cellular consumption. Therefore, dietary fiber is generally intact inside and outside the body. However, despite this fact, certain fiber may be dissolved in certain kinds of solvent such as water.

Fiber is categorized into two, insoluble and soluble fiber. The former is a fiber which does not dissolve in water while the latter is a fiber which dissolves in water. Insoluble fiber significantly promotes the movement of digestive contents by increasing its bulk. This normal intestinal peristalsis then promotes regular bowel movement, thereby, lowering the risk of constipation or irregular bowel movement. Great sources of this kind of fiber include whole wheat flour, wheat bran, nuts and leafy vegetables. On the other hand, soluble fiber dissolves in water but is not absorbed by the body. After being dissolved, the fiber forms into a gel – like substance which alters the absorption of cholesterol and excess sugar thus regulating the blood levels of cholesterol and glucose. Popular sources of soluble fiber include oats, beans, apples, carrots, oranges and barley.

There are many great sources of dietary fiber. However, there are misconceptions on what fruit or vegetable contains rich amount of fiber. Among the commonly mistaken food items are lettuce, tomatoes and celery in the forms of fresh salads. Chemically, these fruit and vegetable contains little amount of fiber only. Another mistaken belief is that a food may be high in dietary fiber just because of its tag which states wheat, multi – grain, natural and enriched. Like for example, oat – bran doughnuts, cookies and grain chips are commonly low in oat bran fiber but instead high in fat and sugar. Therefore, be careful of commercial labels.

Great sources of dietary fiber mainly include fruits, vegetables, whole grains, nuts and legumes. Dietary fiber is important to the body because it can significantly normalize the individual’s bowel movement. Aside from such primary purpose, fiber can also greatly help in lowering the risk of certain diseases such as diabetes and cardiovascular diseases. Indeed, fiber is beneficial and important to the body. However, many questions have come out whether consuming more fiber can be good or bad to the body.

Certain clinical studies have revealed that consuming greater than 35 grams of fiber everyday can significantly influence the digestion and absorption of several vitamins and minerals. This may be technically valid. However, that certain amount of fiber is rarely eaten since most people eat only a small amount of dietary fiber. Therefore, this is not a significant threat to the health of an individual. The benefits of dietary fiber far outweigh the little possibility of adversely altering nutrient absorption and assimilation.

Also, rarely in certain individuals, consumption of more than 50 grams per day of fiber may cause intestinal obstruction. However, this chance is only very little since in most individuals this amount of fiber can improve instead bargain the health of the intestines.

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Date: November 11, 2010 03:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Turmeric, Curcumin, And Good Health

Turmeric and its history

Turmeric, because of its Curcumin content, has many health benefits to humans. Firstly, Turmeric has an anti-inflammatory property. Its active ingredient, Curcumin, has been proven to help reduce inflammation. Decade to decade, Turmeric has been used as an anti-inflammatory agent to treat inflammations of the skin and muscles. Experiments done by researchers also revealed that this herb has been effective in decreasing post-surgical inflammation. This important health benefit of Turmeric is considered to be a result of the herb’s ability to slow down, if not to totally stop, Eicosanoid Biosynthesis, one of the processes the immune system undergoes during an inflammatory response.

Secondly, as a result of its anti-inflammatory characteristic, Turmeric also has an anti-arthritic property. It is widely used as an alternative medicine for rheumatoid arthritis and other autoimmune disorders. In addition, this herb also has a natural painkiller effect. Studies show that it has similar actions to the commonly used medications such as COX-2 inhibitor and Nonsteroidal Anti-inflammatory Drugs.

Thirdly, several studies have shown that Turmeric is also helpful in lowering the level of bad cholesterol in the blood known as the Low Density Lipoprotein or LDL and in increasing the body’s good cholesterol, High Density Lipoprotein or HDL. An increased level of LDL promotes cholesterol plaque deposits to the walls of blood vessels, most commonly in the arteries of heart. These plaques narrow the arterial diameter hence resulting to high blood pressure and even circulation blockage. An arterial block may cause poor circulation and oxygenation to heart muscles leading to cardiac injury then infarction. This is oftentimes the cause of heart attacks. It has also been discovered that Turmeric can promote excretion of dietary fats. Thus, controlling the intestinal uptake of fats, especially cholesterol.

Turmeric - Powerful Antioxidant

This herbal plant can be prepared in the household by pounding and pressing its roots to be able to extract the juice out. It is then mixed with water and may be used topically or by nasal inhalation. The root can also be lightly cooked and eaten. Turmeric is also helpful in earaches and to clear clogged sinuses thus easing breathing. This herb can also be purchased in bulk powder or standardized forms to ensure its beneficial properties are intact.
~facebook~

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Date: October 28, 2009 11:39 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Horse Radish

The horseradish plant is a perennial plant that is part of the Brassicaceae family, which includes mustard, wasabi, broccoli, and cabbages. Native to southeastern Europe and western Asia, the plant is popular around the world today. The horseradish plant grows up to five feet tall and is mainly cultivated for its large, white, tapered root. The intact horseradish root has hardly any aroma. However, when cut or grated, enzymes from the damaged plant cells break down to produce allylisothiocyanate, which often irritates the sinuses and eyes. Once grated, if the plant is not mixed with vinegar or used immediately, the root darkens and loses its pungency. It quickly becomes unpleasantly bitter when exposed to air and heat.

Horseradish has been cultivated since ancient times. The Delphic Oracle in Greek mythology told Apollo that horse radish was worth its weight in gold. Horseradish was known in Egypt by 1500 BC and has been used by Jews from Eastern Europe traditionally in Passover. The plant is discussed by Cato in his treatises on agriculture. It is thought that horseradish is the plant known as Wild Radish by the Greeks. Both the root and leaves of the horseradish plant were used as a medicine during the Middle Ages, with the root used as a condiment on meats in Germany, Scandinavia, and Britain. This herb was taken to North American during Colonial times. It is not certain as to where the name horseradish come from. Some believe that it derives by misinterpretation of the German Merettich as mare radish. Others think the name comes from the coarseness of the root. The common thought in Europe is that it refers to the old method of processing the root called hoofing, in which horses were used to stamp the root tender before grating it.

For at least two thousand years, horseradish has been cultivated. It was brought to America by early settlers and used to treat conditions such as pain from sciatic, colic, and intestinal worms. Horseradish provides antibiotic action that is recommended for respiratory and urinary infections. The volatile oil in horseradish has the ability to work as a nasal and bronchial dilator. Internally, it has been used to clear nasal passages, alleviate sinus problems, help with digestion, work as a diuretic, aid with edema and rheumatism, and cleanse various body systems. Also, horseradish has been used to stimulate digestion, metabolism, and kidney function. This herb helps promote stomach secretions to aid in digestion. Horseradish can be used as a compress for neuralgia, stiffness, and pain in the back of the neck. Additionally, this herb can be used as a parasiticide.

The root of the horseradish plant can be used to provide antibiotic, antineoplastic, antiseptic, bitter, caminative, diaphoretic, digestive, diuretic, expectorant, hepatic, parasiticide, mild purgative, rubefacient, sialagogue, stimulant, and stomachic properties. The primary nutrients found in this herb are calcium, iron, phosphorus, sodium, and vitamins A, B-complex, and P. Primarily, horseradish is extremely beneficial in dealing with loss of appetite, circulation, coughs, edema, excessive mucus, sinus problems, internal and skin tumors, and worms.

Additionally, this herb is very helpful in treating arthritis, asthma, bronchitis, congestion, gout, jaundice, kidney problems, irritated membranes, neuralgia, palsy, rheumatism, skin conditions, water retention, and wounds. For more information on the many beneficial effects provided by horseradish, please feel free to contact a representative from your local health food store with questions.

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Date: October 13, 2008 02:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Polyphenols is an Antioxidant

A lot of new evidence suggests that consuming more plant polyphenols is a powerful way to protect aging arteries. These polyphenol compounds help improve endothelial function, a critical factor in preventing atherosclerosis; inhibit abnormal platelet aggregation which causes most sudden heart attacks and strokes; fight inflammation; and support healthy blood lipids. Polyphenols that are of particular interest are those derived from green tea, cocoa, apples, and black chokeberry, which all complement each other in helping to build the body’s defenses against various ailments.

All throughout history, the medicinal potential of plants has been celebrated. Modern science has found that edible plants are to be valued for their high vitamin and fiber along with their rich store of polyphenols. Polyphenols are found in fruits and vegetables, as well as cocoa, tea, and chokeberry and have been shown to be a type of chemical that may protect the body against some common health problems as well as certain effects of aging. Polyphenols protect cells and body chemicals against damage that is caused by free radicals and block the action of enzymes that cancers need for growth, deactivating substances that promote the growth of cancer. The increased consumption of polyphenols has been associated with a reduced risk of cardiovascular disease and potentially cancer and stroke.

In Aztec culture, cocoa was one of the most highly prized due to its medicinal and stimulant value, along with its taste. The polyphenols found in cocoa occur in a higher concentration than can be found in any other food. They also have antioxidant activity much greater than those found in broccoli or red wine. The catechins and procyanidins that are found in cocoa seem to lower the risk of cancer and heart disease. Cocoa has also been proven in studies to reduce blood pressure, improve insulin sensitivity, and slightly ameliorate the lipid profile. Although cocoa is a healthy and tasteful food, it is high in caloric content and therefore, its ingestion must be accompanied by the careful reduction of calories from other sources.

Many studies have shown that tea polyphenols can be extremely beneficial to human health, possessing anti-obesity, antihypertensive, anti-diabetic, antioxidant, anti-inflammatory, and anticancer effects. Tea is the world’s second most consumed beverage, although less popular in the Western diet. Green tea and white tea retain more polyphenols in their intact form, as oolong and black teas undergo more extensive processing before they are marketed. Tea polyphenols break down in high temperatures therefore; freshly brewed tea contains a higher amount of polyphenols per serving than do tea drinks that are canned or bottled.

Similar to the blueberry, the black chokeberry is high in anthocyanins and antioxidant activity. It is native to eastern North America and has become popular in Eastern Europe and Russia due to its health-promoting potential. This berry protects the liver from chemical poisoning and the stomach lining from ulcers. It also acts as an anti-inflammatory, lowers harmful cholesterol levels, and prevents dangerous swings in blood pressure. Some studies have shown that this berry seems to prevent the harmful mutations in cell cultures, regulates immune function of human white blood cell cultures, and suppressed the growth of human colon cancers.

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Date: July 21, 2008 02:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Fiber?

Fiber often has been called roughage, as it technically is a food component that is undigested and processed through the gastrointestinal tract. Since it readily absorbs water, it helps to add to the bulk that is required in order to form a good bowel movement. Fiber is often described as a complex carbohydrate, which consists of the polysaccharide and lignin substance that often gives structure to the cell of a plant and is the portion of plant food that is not digested.

Fiber which is insoluble has the capability of passing through the intestines intact and unchanged. Unlike fats, carbohydrates, and proteins, fiber does not give the body nutrients or fuel for energy, and has no caloric value. Dietary fiber can only be found in plant components including vegetables, fruits, and whole grains. Primarily, there are only two types of fiber: soluble and insoluble, with some foods containing both types.

Soluble fiber is eventually digested in the large intestine, causing it to have limited bulking power. Soluble fibers dissolve in water and have often been linked to helping prevent blood sugar highs and lows, helping to lower blood cholesterol, lowering the risk of heart disease, helping to control high blood pressure, and encouraging friendly bacteria growth. Soluble fiber can be found in pectin, lignin, gums, mucilages, and other sources such as psyllium, beans, apples, pears, and oat bran.

Soluble fiber doesn’t usually seem like fiber. It is digestible and, when broken down, it creates a gel as it absorbs water in the intestinal tract. It does not bulk the stool to the extent of insoluble fiber, but it does slow down the rate at which food is digested. Soluble fiber is found in vegetables, particularly onions, bulbs, leeks, and asparagus, and also fruits, including dried varieties.

Insoluble fiber remains undigested for the most part and promotes a faster stool transit time. Insoluble fiber can keep the bowel clean and operative and also help to bind dangerous toxins and hormones in order to promote better excretion. Insoluble fiber also fosters regularity in the body, contributes to better digestion, prevents constipation, and helps to lower the risk of bowel disease.

Insoluble fiber is primarily composed of cellulose and hemicelulose. Cellulose is a non-digestible form of fiber, found in outer portions of vegetables and fruits. Bran or seed covering of whole grains is another type of insoluble fiber. Hemicellulose fibers remain unchanged and absorb water as they travel the digestive tract. They increase stool bulk and transit time, preventing constipation and conditions like hemorrhoids. Stalks, stems, peels, and fruit and vegetable skins are all made up of insoluble fiber. However, the insoluble fiber content of fruits is actually found in its flesh and stringy membranes, rather than its peelings.

The average person needs a good variety of foods that contribute to at least 35 grams of dietary fiber in our diet daily. Most foods contain both types of fiber, but the ones that are most fiber rich are not usually the ones that we commonly eat. Whole grain cereal, raw fruits and vegetables, split peas, beans, lentils, millet, and barley are the best sources of fiber. Unfortunately, statistics have shown that most of us only get 9 grams of fiber each day, if we are lucky.

Finally, fiber has the ability to increase fecal bulk by retaining water, decrease stool transit time, keep blood sugar levels more stable, lower blood serum and liver cholesterol, help prevent weight gain by slowing the rate of digestion and absorption and controlling hunger, expediting the removal of dangerous toxins, binding with bile salts to help decrease the risk of gallbladder disease and certain types of cancer, and creating the presence of healthier intestinal bacteria.

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Date: June 30, 2008 04:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fennel

If there has ever been an overlooked vegetable, it would definitely be fennel. Some people have an aversion to its licorice-like scent, while others feel as if fennel is a bizarre and obscure vegetable that they have no interest in learning how to prepare. However, those who have discovered it know that ignoring fennel is a waste of a versatile vegetable’s amazing flavor and healthful benefits. Even those who already cook with fennel might find that they aren’t taking advantage of its versatility. For example, many people use only the delicate, lacy parts of fennel as a flavor-enhancing garnish for soups or salads. Others stick to just using the green-white bulbs, while tossing the remaining pieces aside. However, there’s no season like now to start using and enjoying all the parts of fennel.

Fennel is available from autumn until early spring and both its stems and bulbs have been found to contain many nutrients. Fennel spice, which is made from the vegetable’s seeds, can be found year round, as it is one of five spices in Chinese five-spice powder. One cup of raw, sliced fennel is a huge source of vitamin C, folic acid, fiber, and potassium. History has shown that fennel can be taken to alleviate bad breath, indigestion, intestinal spasms, cramps, and gas. It is thought that Puritans chewed the seeds in order to tame hunger during fasts. Recently, scientists have found that fennel contains antioxidants which promote good health.

In order to gain these healthful benefits, be sure to purchase white or pale-green fennel that has clean, firm bulbs. The bulbs should not be split, bruised, or spotted, while the stalks that grow from the bulb should be relatively straight. Additionally, the vegetable’s fronds would be green but not flowering because blooms indicate that the bulb is past maturity. When consumed right away, fennel is at its best. But, it can be kept in the crisper for up to four days. Be sure to wash it before using its base in hors d’oeuvres, salads, and gratins. Also, make sure to reserve its fronds in order to enhance dishes in a potent way. With such versatility in the kitchen, there is absolutely no excuse not to include fennel in your meals this season.

Once you discover that fennel is both crunchy and slightly sweet, you will want to incorporate it into many of your daily meals. Thankfully, fennel can enhance many dishes and make them extraordinary. Here are some quick ideas for using fennel this season. You can thinly shave the desired amount of a fennel bulb and toss it with a bit of olive oil, fresh lemon juice, and a small amount of Parmesan cheese to make a fennel salad at moment’s notice. Another option is sauté sliced fennel with equal parts of onion and bell pepper in order to make a simple vegetarian side dish. One can take advantage of fennel’s ability to enhance flavors by adding fennel with tuna or grilled sea bass. Fennel can also be cut vertically, leaving bulb, stalk, and leaves intact and then brushed with olive oil and grilled until lightly browned. Another idea is to garnish your favorite vegetable soup with coarsely chopped fennel fronds.

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Date: April 25, 2008 02:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Oregano oil hi in Carvacrol

VitaNet ®, LLC is pleased to distribute Nature’s Answer Oil of Oregano—one of the finest quality oregano oils available today. Nature’s Answer offers you a concentrated oil of true oregano, Origanum Vulgare, steam-distilled in a base of extra virgin olive oil. There is a lot of confusion about oregano, because many plants throughout the world are called oregano. For example, marjoram (origanum marjorana) is a close cousin to true oregano, and Spanish and Mexican oregano are actually different plant species. It is important to be aware of these differences, because only Origanum Vulgare contains high amounts of the active ingredient, carvacrol. This is the exact species that Nature’s Answer uses in its products.

It takes approximately 200 pounds of oregano to produce two pounds of Nature’s Answer Oregano Oil. This highly concentrated form yields a quality plant product, retaining all the important volatile oils intact, true to Nature’s Answer’s philosophy of maintaining the plant’s Holistic Balance.

Holistic Balance guarantees that the natural constituents of our herb products are in the same synergistic ratio as those found in the plant; an herb of this type reflects the natural balance of the plant, and all of its many micronutrients.

Oregano is rich in nutrients including vitamin A and C, niacin, calcium, magnesium, zinc, iron, potassium, copper, boron, and manganese. It also contains the active chemical constituents, thymol and carvacrol. These components have shown strong activity in protecting cells against foreign organisms.

The protective properties of oregano have been recognized by traditional herbalists throughout history as well as supported by modern scientific research. Oregano is also a powerful antioxidant, offsetting the adverse effects of free radicals on out bodies. Oregano oil has been shown in scientific studies to support intestinal, digestive and respiratory health and can also be used topically for minor skin irritations.

Each four-drop dose of Nature’s Answer Oil of Oregano provides 13mg of oregano oil, which is guaranteed to contain a minimum of 7mg of carvacrol. Nature’s Answer Oil of Oregano liquid and its high quality oregano oil in softgel form are always on deal at VitaNet ®, LLC Health Food Store.

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Date: January 21, 2008 02:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Genetically Engineered Foods May Cause Rising Food Allergies

Arguments made by the Environmental Protection Agency, which regulates plant produced pesticides, tell us not to worry about the thought of consuming toxic pesticides. Instead, they say that the pesticides used, Bt, are produced naturally from a soil bacterium which has a history of safe use by organic farmers who have used the solution for yeas as a method of insect control. Genetic engineers simply remove the gene that produces Bt and insert it into the DNA of corn and cotton plants, making the plant do the work, instead of the farmer. They also say that the Bt toxin is quickly destroyed in our stomach, and even if it survived would not harm humans or any other mammals. However, these arguments are solely that, arguments, which are unsupported and refuted according to a lot of research.

When a study was done, spraying natural Bt over areas in Vancouver and Washington State for months, about 500 people reported reactions, mostly those being allergy or flu-like symptoms. Six of those people had to go to the emergency room, while workers who applied the Bt sprays reported that their eyes, nose, and throats were irritated. Similarly, farmers who were exposed to liquid Bt said that they had reactions such as infection, ulcers on the cornea, skin irritation, burning, swelling, and redness. One woman even reported fever, altered consciousness, and seizures when she was accidentally sprayed with Bt. This proves that the statements of Bt doing no harm on humans is extremely false. As for being destroyed in the digestive system, studies on mice disproved this as well. Results of these, and other, studies showed that plant-produced Bt is always active and much more likely to trigger an immune response than the natural version.

Additional studies in 2005 reported by medical investigators in India found that hundreds of agricultural workers are developing severe allergic reactions when they are exposed to Bt cotton. This exposure includes picking cotton, loading it, cleaning it, or simply leaning against it. Some people that work at ginning factories must take antihistamines daily in order to go to work. These reactions are only trigger with the Bt varieties and the symptoms are virtually identical to those that were described by the 500 people in Vancouver and Washington who were sprayed with Bt.

Another study was done on the basis that Bt-toxin is produced in GM corn and can be eaten intact. It is also in pollen which can be breathed in. Therefore, a village of Filipino people were studied in 2003 when an adjacent Bt cornfield was pollinating. 100 of these people were stricken with disease which included symptoms such as headaches, dizziness, extreme stomach pain, vomiting, chest pains, fever, and allergies, along with respiratory, intestinal, and skin reactions. The symptoms first appeared in those that were living closest to the field and then progressed to those further away. When the same corn was planted in four other villages the following year, the same symptoms returned in all four areas only during the time of pollination.

All of these studies confirm that GM crops engineered to produce built-in pesticides provoke a great variety of immune responses. Allergic reactions are a defensive and often harmful reaction from the immune system to an external irritant that occur when the body interprets something foreign as harmful and offensive and acts accordingly. Since all GM foods have something foreign and different, it is easy to see why the body would react in such ways. As the GM foods arise on the market place make sure you scan each label to make sure you are not buying a GM vegetable of fruit. Check every label this way you will not be stricken with debilitating symptoms that may prevent you from going to work. Always say NO to GM foods and support your organic foods store.

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Date: May 05, 2007 01:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Selecting the Right Probiotic is the Key to proper digestion

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Date: March 08, 2007 02:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Oil of Oregano – The Natural Antiseptic

Oregano is an aromatic herb that grows in the Mediterranean region, and is cultivated in many areas of the world. It is a member of the Lamiaceae or mint family, a plant family recognized for square stems and opposing pairs of leaves. The ancient Greek’s original name for this plant, “oreganos”, translated to “Delight of the Mountains”. It earns this name because the fragrance that is exuded, which has been described as complex, warm and spicy. The Greeks believed that if their cows ate oregano, it gave the meat a better flavor. Today, Oregano is recognized internationally as a culinary spice. It is a popular herb with Americans, especially in the distinctive aroma of Italian style cooking. Aromatic spices have been used through out the world for centuries for both their distinctive flavor and aroma as well as for their medicinal qualities.

Oregano is rich in vitamins and minerals including vitamin A and C, niacin, calcium, magnesium, zinc, iron, potassium, copper, boron and manganese. In addition, the herb contains many active chemical constituents that provide beneficial support to our bodies, such as thymol and carvacrol these components strongly discourage the growth of microorganisms, as action recognized by traditional herbalists throughout history as well as supported by modern scientific research. Oregano additionally provides antioxidant activities, useful to offset the effects of free radical damage.

There is a lot of confusion about oregano, because there are many plants throughout the world that are called oregano. Marjoram is often referred to as oregano, because it is a close cousin to the “true” oregano, and the genus and species name of marjoram is Origanum marjorana. To add to the confusion, the plant called oregano in Spain, Thymus nummularius, is different than Mexican oregano, Lippia graveolens. It is important to be aware of this because different species have different chemical constituents. The active ingredient, carvacrol, is found in high amounts only in “true” oregano, origanum vulare, the exact species that vitamin supplement manufacture use.

It takes approximately 200 pounds of oregano to produce 2 pounds of oregano oil. This highly concentrated form provides you with a quality plant remedy containing all the important volatile oils intact, thus remaining true to maintaining the plant in its holistically balanced state.

Oregano oil is exceptional in its ability to destroy many different kinds of pathogenic (disease-causing) microorganisms. It has a stronger effect than commercial preparations of phenol, a well-recognized medical antiseptic. Disease causing microorganisms including bacteria, fungus, virus and parasites are involved in illnesses ranging from colds and flues to gingivitis of the gums, athlete’s foot and candida. Oregano oil has been shown in scientific studies to actively inhibit and destroy E. Coli, candida albacans and the bacteria’s that cause strep and staff infection. It has been used for diarrhea, intestinal gas and digestive problems, as well as sore throats and minor breathing difficulties in traditional herbology. Oil of Oregano can act as an immediate first aid for insect bites and minor cuts and scrapes as well as dandruff, diaper rash and other skin disorders.

Unlike pharmaceutical drug antibiotics, Oregano oil does not cause the development of resistant strains of bacteria. Although it is always possible for an individual to have an allergic reaction to any substance, there are no known adverse effects to Oil of oregano.

Try Oil of Oregano on the skin for external conditions such as athlete’s foot. A few drops can be diluted in a teaspoon of water and used to brush the gums to help with gingivitis. Due to its high concentration, suggested internal use is just four drops (Start with one drop) in a full glass of water, three times per day. Each four drop dose of Nature’s Answer Oil of Oregano provides 13mgs of Oregano oil, which is guaranteed to contain a minimum of 7mg of Carvacrol. It is also available from Nature’s Answer in soft gel form.

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Date: March 02, 2007 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Power Plant of the Amazon

Enzymatic Therapy Amazon Herbs

It may surprise most Americans to know that rainforest plants are the original source for one-fourth of the chemotherapy medications used today. Plants offer a plethora of beneficial compounds, and rainforests contain a superabundance of beneficial plants.

In fact, plant medicines are the most widely used medicines of all types in the world. Over eighty-five percent of the world’s population uses plant and herbal medicines as their primary medicines. That’s 5.1 billion (5,100,000,000) people worldwide! While Americans overwhelmingly use synthetically manufactured pharmaceuticals to cure their ills, the vast majority of Earth’s inhabitants use healing plant medicines instead.

One of the most powerful healing rainforest plant medicines is cat’s claw, or Uncaria tomentosa. This high climbing woody vine grows at the base of tall trees in the Peruvian rainforest. The plant’s claw-shaped thorns latch onto the trees and spiral further upward, nourished by the lush rainforest environment. For over 2,000 years, the Ashaninka, a tribal people of the Peruvian rainforest, have used the root of U. tomentosa to treat illnesses in the tribe, including asthma, bladder infections, infected wounds, arthritis, bone pain, bowel inflammation, and cancer.

Q. I’ve heard about cat’s claw, but what does it do and how do I know which one is right for me?

Cat’s claw might be one of the most confusing (and most effective!) nutritional supplements available in health food stores today. One reason that it’s so confusing is there are so many kinds of cat’s claw supplements-there are cat’s claw leaves, cat’s claw bark, and even cat’s claw twigs. While each of these supplements claim to help the immune system, it is the root of Uncaria tomentosa that is proven to impart the true cat’s claw health benefits.

Scientists, who have extensively studied every part of the plant, discovered that extracts made from selected cat’s claw roots possess the healing power to treat and prevent diseases like cancer, rheumatoid arthritis, ulcers and degenerative diseases. In addition, it demonstrates anti-inflammatory, anti-viral and anti-microbial benefits.

Adding to the confusion is the fact that not all Uncaria tomentosa roots actually contain healing properties.

Healers in the Ashaninka tribe attribute the healing properties in cat’s claw to the “good spirits” that live in the plant’s roots. The Ashaninka healers, or sancoshi, are able to actually “see” the good spirits hidden inside the root of the plant before they harvest them.

Some cat’s claw plant roots have the good spirits. Some don’t. If the good spirits are mixed with any cat’s claw root without good spirits, the healing power is lost. While there are no apparent differences in the plants or the roots to the untrained eye, only certain cat’s claw roots possess the power to heal. And, for a very long time, only the Ashaninka tribal healer seemed to be able to identify them. They call the good spirit cat’s claw Saventaro, or “powerful plant”.

However, scientists who were given cat’s claw roots by the Ashaninka to study in the laboratory discovered that they could “see” the good spirits, too! Using high performance liquid chromatography, or HPLC, a laboratory process that identifies various chemical compounds, the good spirits of cat’s claw roots were revealed to be important medicinal compounds called pentacyclic oxindole alkaloids (POAs). Research has learned that POAs provide powerful benefits for the human immune response.

Q. Why are good spirits, or POA’s, good for the immune system?

Cat’s claw POAs work to keep us healthy by directly interacting with white blood cells, the backbone of our immune system. Our white blood cells are the disease fighting cells of the human body. These highly specialized cells fight diseases we catch, such as colds and flu, as well as diseases that start within our own cells, such as cancer and autoimmune diseases. There are many kinds of white blood cells; each has a specific job to do in fighting diseases.

Certain POAs help white blood cells called macrophages work faster. The macrophages’ job is to engulf and digest foreign material. This means that macrophages can ingest m ore bacteria and disease causing microbes when they are exposed to POAs. The scientists also discovered that POA cat’s claw extract increases the production of a chemical protein called interleukin that is secreted by macrophages. This macrophage-secreted interleukin (IL-1) has important immune enhancing properties. IL-1 alerts resting white blood cells and spurs them into action. It also helps make other biochemicals that are essential to an activated immune system.

POAs also help B cells. B cells are white blood cells that make antibodies that kill germs. Each B cell is programmed to make one specific antibody that is effective against one specific germ (such as a bacteria, virus, or fungus). When scientists looked at the number of B cells after they were exposed to POA cat’s claw root extract, they found that the B cells had increased significantly, resulting in an increased supply of antibodies. And perhaps most importantly as they relate to cancer, the POAs in cat’s claw root extract help increase the number of T cells, the true soldiers of the immune system. There are many different kinds of these white blood cells, including Helper T cells, Suppressor T cells, and Killer T cells. Increased Helper, Suppressor, and Killer T-cells can more effectively destroy cancer cells. Increasing the number of circulating T-cells is very important in a disease like AIDS as well.

Q. Can cat’s claw and other plants in the rainforest really cure diseases? Isn’t that just folklore?

It’s folk use and modern science combined-plants have long been known for their ability to kill cancer cells. In fact, the National Cancer Institute (NCI) has identified over 3000 plant extracts that can kill cancer cells. More than 70 percent of these plants are found only in the rainforest.

Q. What is it about the rainforest that gives plants like cat’s claw these cancer killing compounds?

Most of the time when we talk about rainforests, we’re talking about the tropical rainforests. While other forests, like the old-growth temperate forests of the Pacific Northwest, also have high rainfalls and tall trees, the tropical rainforests located near the equator are where most plant medicines come from.

The Amazon rainforest in South America is the world’s largest, covering an area about two-thirds the size of the continental United States. Depending on the elevation and distance to the equator the Amazon rainforest receives between 160 and 400 inches of rain per year. The rain is spread pretty evenly from January to December-it’s always the rainy season-and the temperatures remain between 75-80 degrees Fahrenheit all year.

This fertile environment continually recycles itself. When leaves fall from the trees, flowers wilt, and animals die in the rainforest-all of the nutrients are recycled back into the roots of the trees and plants. Because the rainforest reuses almost everything that falls to the ground, the plant growth is amazingly rich in alkaloids and other medicinal compounds. Researchers think these compounds and alkaloids, like POAs, protect the plants from illness and insect attacks. These are the very same compounds that protect us from disease.

Q. When the Ashaninka harvest the cat’s claw roots, does it impact the rest of the plant?

No. The Ashaninka work intelligently to keep rainforest cat’s claw plants perpetually healthy. The Ashaninka employ responsible and innovative harvesting techniques to keep the plants alive and tribal members healthy. Individual cat’s claw plants are never completely harvested. Only one third of the lateral roots are collected at any one time to allow re-growth by the remaining root. Once a plant’s lateral roots have been partially harvested, that plant is left to regenerate, and no more root is harvested from it for 10 years.

Q. Why are the Ashaninka willing to share their cat’s claw?

They are generous people. The Ashaninka see no benefit in hoarding cat’s claw for themselves alone. They also want to make sure that the plant’s healing properties continue on. As their homelands continue to be destroyed by deforestation, rainforest peoples are also disappearing. There were an estimated ten million tribal and indigenous peoples living in the Amazonian Rainforest in 1510. Today there are less than 200,000.

Since the 1900’s more than 90 indigenous tribes have died out and disappeared. Each time a rainforest medicine man or woman dies without passing their arts on to the next generation, the tribe and the world loses thousands of years of irreplaceable knowledge about medicinal plants. With them, centuries of accumulated knowledge of the medicinal value of rainforest species have been lost.

A good example of the impact of this loss can be seen in cat’s claw. When European explorers began venturing into the Amazon River basin, t hey were skeptical of the stories the Ashaninka people told them of U. tomentosa’s amazing healing powers. But when the explorers became sick with colds, flu, or other illnesses, they harvested cat’s claw root for themselves and gave the plant a try. Sometimes the explorers got better when they used the cat’s claw root, sometimes they stayed the same.

Q. Why didn’t the cat’s claw root help all the explorers?

Because some cat’s claw plant roots have good spirits-POAs-and some cat’s claw plant roots have tetracyclic oxindole alkaloids, or TOAs. While the POAs have very powerful effects in the immune system, the TOAs have different effects in the body, none of which help the immune system cells at all. All U. tomentosa plants look virtually identical, so it’s hard to tell if they have the healing POAs or non-helpful TOAs.

What makes cat’s claw identification even more challenging is the fact that plants with POAs one year will have TOAs the next. Cat’s claw plants seem to change their alkaloid chemotypes at will, an incredibly powerful accomplishment for a plant to possess. Harvesting of cat’s claw roots that contain POAs is very tricky. Unless the person gathering the root extract is an Ashaninka sancoshi. These medicine men know which cat’s claw to use; they can actually “see” the good spirits hidden inside the root. When scientists studying cat’s claw discovered they could “see” presence of TOAs using HPLC technology, they were able to harvest cat’s claw root extracts with POAs that consistently helps people get and stay healthy.

Q. Do some cat’s claw root extract supplements contain TOAs?

Yes they do. And buying those products will only benefit the cat’s claw distributor; they won’t help you stay healthy. When cat’s claw root is harvested from the rainforest, responsible supplement maker examine the root with HPLC to make sure that only POA roots are collected. But, this identification of the chemotypes takes significant time and costs money. For these reasons, many cat’s claw distributors don’t include this important process in their harvesting. The POAs and TOAs are simply just mixed together and sold as a cat’s claw product with no mention of any alkaloid content on the label.

Q. Why should I avoid TOAs?

While the POAs in cat’s claw root extracts have numerous benefits to the immune system, the TOAs have different effects in the body, none helping the immune system cells. Most importantly, however, when POAs and TOAs are mixed together, the TOAs actually work against the POAs. TOAs reduce the capacity of POAs to beneficially modulate the immune system.

Q. How can I be sure the cat’s claw I buy is POA cat’s claw?

Read the label of the cat’s claw root extract product you are considering buying. If it does not clearly state that it is the high POA cat’s claw, then chances are that it’s not.

Q. What do the Ashaninka receive in return for the cat’s claw harvesting?

The Ashaninka and reputable distributors of cat’s claw root extract have established a mutual and ethical relationship. Both groups benefit from the sale of the plant material. Maintaining this relationship is important for both the tribe and the distributors.

The distributors are paying a fair price for the raw material directly to the tribe. No intermediary is involved. This payment covers the raw material itself, a license-fee for the k knowledge of the plant, and a guarantee (from both sides) of a lasting relationship. Payment is also made for the protection of the rainforest. No deforestation is allowed. The area where the cat’s claw materials are processed is also leased and payment is made for this, as well.

This arrangement allows the Ashaninka to make independent decisions in how to spend this income from sale of their cat’s claw plants. They have been able to make improvements in the tribe’s water supply and in their living areas. They are also able to obtain outside medical aid as needed and provide for education of their children.

The partnership with cat’s claw distributors has created a sustainable resource for the Ashaninka. The tribe has been able to not only preserve their rainforest, but also compete financially with unsustainable income sources offered by timber and agricultural firms.

Q. Why is it important to preserve the rainforest?

The most amazing fact about these impressive medicinal plants is the vast number that5 has yet to be discovered. In fact, the rainforest’s abundance is one reason it is home to so many healing plants. Within a four square mile patch of rainforest, you could see 1500 species of flowering plants, 750 species of trees, 125 mammal species, 400 species of birds, 100 reptile species, 60 amphibian species, and 150 different species of butterflies.

Unfortunately, not everyone looks to the rainforest for the same reasons. Many consider its real value in board feet and cultivated acreage. The forces pushing industrial development move quickly; experts estimate that we’re losing over 130 plant, animal, and insect species every day/ That amount to almost 50,000 species a year.

A combination of logging, petroleum interests, cattle grazing operations, and, of course, our own consumer appetites are putting pressure on rainforest resources. The consequences are sobering:

• Rainforests once covered 14% of the earth’s land surface; it’s only 6% today
• The last remaining rainforests could be consumed in less than 40 years.
• Nearly half of the world’s species of plants, animals and microorganisms will be destroyed or severely threatened over the next quarter century due to rainforest deforestation.

By leaving the rainforest intact, however, and harvesting its many nuts, fruits, oil-producing, and medicinal plants, the rainforest has more economic value than if it was cut down for timber or to make grazing land for cattle. If managed properly, the rainforest can provide the world’s need for sustainably harvested natural resources on a perpetual basis. That’s what the Ashaninka are doing with their cat’s claw harvesting.

Conclusion

The discovery of medicinal plants is dependent upon healthy rainforests. When an acre of tropical rainforest is lost due to deforestation, the impact on the number of plant and animal species lost and their possible uses is staggering.

We can all help the development of sustainable rainforest industries. By purchasing renewable and sustainable rainforest products, like POA type cat’s claw root extract, we are keeping rainforests alive and well. By benefiting from the innate wisdom of the Ashaninka people we are keeping ourselves just as alive and well. By honoring the science and the sacred of the world’s rainforests, like my friend the oncology nurse, the massive wealth and diversity will be there for generations to come.

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Date: October 17, 2006 01:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Carbohydrate Loading

Carbohydrate loading is an ergogenic technique devised for endurance athletes to trick the muscles into storing more fuel than it normally would. Although carbohydrate loading has been hailed as an innovative training technique in the past few years, the discovery of carbohydrates as the preferred fuel of the body dates back several decades. In 1939 two scientists named Christiansen and Hensen demonstrated that the body burns carbohydrates before drawing upon its fat and protein. The research found that the body readily uses carbohydrates as fuel for the muscular and nervous system with minimal wastage and toxic by products – unlike the case with protein and fats.

The body stores carbohydrates in the form of glycogen in the muscles and liver. This glycogen helps the liver to detoxify otherwise dangerous substances. It also supplies a readily available source of glucose to maintain the essential blood sugar level. Glycogen stored in a muscle is available for energy use for only that particular muscle, unlike glycogen stored in the liver, which is available systemically. At rest, and during low-intensity exercise, the body burns about an equal mixture of fat and carbohydrate for energy purposes. However, as work intensity increases, carbohydrates become the dominant fuel because of its quick availability. Laboratory research has shown that an exercise intensity of less than 40-50 percent VO2 max, the body burns mostly fat, and the degradation of stored glycogen is minimal.

The situation changes during high intensity exercise, when carbohydrates become the sole source of energy. The activity itself is limited by the availably of glycogen as an energy source.

Muscle glycogen is five times more available as an energy source for intensity exercise as compared to liver glycogen. When the muscle glycogen becomes depleted, the muscle its self begins to fail, and fatigue rapidly sets in marathon running, this dreaded phenomenon is known as “hitting the wall”.

Since it is obvious that the availability of glycogen is a limiting factor in endurance athletic events, exercise physiologists devised ways to increase glycogen storage in the body. In 1967 two Swedish exercise physiologists came up with carbohydrate loading, also called glycogen loading, as a method of supper-compensation of glycogen through diet and exercise.

Hydrate loading usually is approached by any of the following means:

• Consumption of high (complex) carbohydrate and high protein foods while limiting intake of refined sugars, 3-4 days before competition. This results in a glycogen level 40-60 percent above normal.
• Exercise to exhaustion for several days, followed by a carbohydrate-loading period. This will deplete stored glycogen and then double its reserves.
• A combination of low carbohydrate consumption and exhaustive exercise. The athlete eats only proteins and fats for 3 days, followed by eating only carbs for the next 3 days. On the carbo-concentration days, the athlete exercises minimally, so as not to interfere with the glycogen storage process.

According to researchers David Costill, Ph.D., carbohydrate consumption in excess of 600 grams daily won’t result in proportionally larger amounts of synthesized glycogen. In the first 24 hours of carbo-loading, the type of carbs eaten is not of critical importances. However, after the second day, Costill suggests eating complex rather refined or simple sugars.

Complex carbs are those which contain lots of intact fiber, such as whole grains, fruits and vegetables. An exception to this rule is pasta, which is a refined sugar but is good to ingest during carbo-loading. Complex carbs tend to maintain a steady output of the hormones insulin, which activates the enzymes glycogen synthetase, essential for effective glycogen storage.

Most experts today advocate a gradually tapering exercise program while increasing carbo consumption to about 525 grams daily. This avoids the problems associated with the low-carb period, such as fatigue, weakness, potassium loss and muscle tissue loss.

One day prior to competition, the athlete rests completely and consumes about 550 grams of carbohydrates.

The carbohydrate loading program should be limited to three times a year. More often than seems to decrease its effectiveness. Costill suggests that athletes engaged in intense exercise on a daily basis consume about 70 percent of their daily calories in carbohydrates. This will maintain adequate glycogen levels in both the liver and muscles, according to Costill.

Carbohydrate loading is of no real benefit in athletic events lasting less than 60 min, because lesser activity time does not deplete glycogen levels enough to inhibit work capacity of endurance.

Carbohydrate loading isn’t for everyone. Each gram of cellular glycogen is stored with 2.7 gram of water. This rapid water storage makes some people feel stiff and tight, resulting in decreased performance. The only way to determine if the carbohydrate loading works for you is to try it – carefully!

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Discount Vitamins

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Date: August 26, 2006 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Remifemin symptomatic relief, scientifically supported*

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Date: July 08, 2006 01:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acidophilus pearls

Acidophilus pearls is a prebiotic dietary supplement designed to help support digestion and a healthy intestinal system. It provides a combination of two different active, live cultures to support overall health of the intestinal tract. Acidophilus pearls are processed using an advanced, patented, encapsulation technique, which results in a product that is stable at room temperature for up to 18 months. Many other live bacteria products are unstable at room temperature, and fail to meet their level claim in less than 12 months after manufacture. Additionally, the patented True Delivery Technology pearl capsule protects the bacteria from harsh stomach acid so they can be released live and intact in the intestines, where they need to arrive in live form to perform their beneficial function.

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Date: April 29, 2006 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The True Whey, boost your immune system

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Date: April 29, 2006 01:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Perplexed about Protein? immunoglobulins to boost the immune system.

The Wellness Revolution

Perplexed about Protein?

As protein and whey powders have advanced in popularity, the confusion about them has grown. In particular, protein processing technology has advanced by leaps and bounds; consumers are being presented with protein claims and counter-claims that are highly contradictory.

The confusion is part of a rapid growth. Little Miss Muffet’s quiet dish of curds and whey has expanded from a minor sideline aid for weight lifters, with sales increases around to percent a year, into an explosive $1 billion a year industry, with some companies announcing sales growth of 110 percent in just the last year.

The increase in market is from whey’s expanding appeal. As new technology has made whey’s nutritive value beneficial to a wide range of consumers, more people are using whey, and whey is being added to more products. The problem is, those advanced nutritive qualities are not included in all whey products. The fantastic immune benefits, for example, apply to only the top tier of whey products.

Protein Quality

The standard of protein quality—the ability to provide indispensable amino acids—is judged on the basis of digestibility, nutrients, and amino acid composition. Whey has historically been acknowledged as on of the best sources of high quality protein.

With the increasing popularity of whey, attention on new processing methods has raised the bar on quality, and new products have greatly expanded nutritional values. What may have been an acceptable high-quality whey protein a few years ago, no longer makes the grade. Tony Lucchesi, Natural Sales Trainer at Source Naturals says, “The different processing methods have changed the entire protein market.”

He explains, “In separating casein from whey, (a process used to make cheese), most processing methods use heat, chemical modification, or pH adjustments. These all damage the native protein structure. The result is little or no biological activity in the whey product. All the low temperature drying and micro-filtration won’t help if the raw material is denatured before a protein is dried and brought to market.”

Damaged Proteins

Damaged protein may have been acceptable a few years ago, but it isn’t now. Lucchesi continues, “Animal experiments have shown that polypeptides—whole, non-denatured proteins—have greater nutritional value than protein isolates.”

Protein isolates are what is left after the pasteurization process. The protein has traditionally been “Cross cooked” out of its normal balance. “What you have left are incomplete bits and pieces of whole protein,” he says. These protein bits have only partial nutrients.

New Whey

The latest introduction to the protein category are concentrates, which are intact, biologically-active whole proteins. The entire difference is in the processing; high heat, acids, and traditional methods of separating the caseins from the whey are no longer used. The new processing preserves the nutrients of the protein. This is the method that is the basis for a new Source Naturals whey product, True Whey.

Lucchesi says, “TRUE WHEY is different in that it was designed to provide nutritional support for enhanced immune function. The entire process was designed for nutritive value. The preservation of these nutrients—lactoferrin, glutamine, immunoglobulins—give TRUE WHEY a huge benefit to athletes, children, and anyone interested in boosting their immune system.”

Per serving, TRUE WHEY offers 8 grams of un-denatured protein that includes 900 mg immunoglobulins and 190mg of lactoferrin. Its vanilla flavoring has gotten very high reviews, and it has a two-year shelf life. It appears that the bar has truly been raised in the whey protein category!

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Date: February 11, 2006 09:28 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Potent Antioxidant Protection *

Goji berry possesses a unique combination of flavonoids, vitamins, minerals and polysaccharides that are thought to be responsible for the antioxidant and anti-aging properties attributed to Goji. Studies have been conducted which characterize some of these antioxidant nutrients and show possible beneficial effects of the berry and its extracts on various systems and organs.

In a study published in 2004, scientists undertook an experiment to assess whether Goji berries contained compounds that would be known to exert potential beneficial effects on skin complexion and anti-aging properties. After analyzing the berry, leaf and roots of the Goji plant, they found that the Goji berry contained a unique analog of vitamin C known as 2-O-(beta-D-glucopyranosyl) ascorbic acid. They determined that this compound was unique to the berry and not found in the other parts of the plant. Furthermore, the vitamin C compound was present in levels equivalent to those found in citrus fruits such as lemons. However, the question remained as to whether this vitamin C analog served as a precursor to vitamin C when ingested in the body. A further experiment in rats was performed to determine the intestinal absorption and tissue uptake of this vitamin C analog. The results showed that some of the compound was indeed metabolized into vitamin C in the blood, while the rest was absorbed intact. These studies suggested that the compound was easily transported from the blood into cells and tissues, where it is activated to active vitamin C. Therefore, the vitamin C from Goji berries seems to be highly absorbable and targeted for delivery to the cells that utilize it.1

Zeaxanthin is a carotenoid that is widely distributed in fruits and vegetables and, along with lutein, is present in significant amounts in the macula of the human eye. Studies suggest that the presence of zeaxanthin is highly desirable for healthy visual function. Goji berries are used in traditional Chinese herbalism to support eye health and are also known to contain a high level of zeaxanthin dipalmitate. Researchers compared the bioavailability of this naturally esterified zeaxanthin to that of an unesterified form in 12 individuals who underwent a 23-day study in which they received one form or the other, and then switched. Administration was done on day one followed by a three-week washout period. The individuals were then crossed over to get the other form on day 23 in a single administration. Analysis revealed that the esterified zeaxanthin from Goji berry caused a higher increase in plasma levels than the non-esterified form, indicating higher bioavailability.2

A second study confirmed these findings. In this study, fourteen individuals consumed 15 grams of whole Goji berries daily for 28 days. These individuals were compared to thirteen age and sex-matched controls who did not consume the berries. Fasting blood samples were taken for all individuals before and after the 28-day period. Results indicated that zeaxanthin plasma levels increased 2.5-fold in the group who consumed the berries daily, suggesting the high bioavailability of zeaxanthin from the berries.3

Goji berry was also studied on various measures of antioxidant activity. Researchers subjected three Chinese herbs, one of which was Goji berry, to various assays of reactive oxygen scavenging potential. The results indicated that all of the herbs had significant free radical scavenging properties; however, Goji berries showed the most potent scavenging effect in the assays. Goji berry was especially strong at inhibiting the formation of superoxide anion and scavenging free radicals. The researchers concluded that among these herbs, Goji could be considered the best antioxidant to promote healthy aging.4

An interesting study was performed in human skin cultures to determine the mechanism of the potentially protective effect of Goji berry extracts. Researchers found that bathing human skin cultures with an extract from Goji berry impacted the function of several enzymes that promote skin aging. This provides evidence of an anti-aging and antioxidant effect of Goji berry extract in these human skin cultures. Researchers also noted that when these skin cultures were subjected to suboptimal growth conditions (lack of adequate nutrients), supplementing the medium with this Goji berry extract allowed the skin to maintain normal metabolic functions.5 Goji berry extract contains numerous compounds that confer potent antioxidant protection to various tissues.*

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Date: December 08, 2005 04:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Co-Enzyme B-Complex Fact Sheet

Co-Enzyme B-Complex Fact Sheet

LIKELY USERS: People with poor digestion or low stomach acid, People needing ENERGY, People desiring metabolism support.

KEY INGREDIENTS: CoEnzyme B-Vitamins plus synergists

MAIN PRODUCT FEATURES: B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as cofactors in biochemical reactions. NOWR Co-Enzyme B-Complex contains B Vitamins already in their active or "Coenzyme" forms. This enables the body to use them more quickly and efficiently because, once absorbed, they are transported directly to their site of action, requiring no conversion. 1

B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes 1, 2. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as coenzymes in biochemical reactions 1, 2.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOWR Co-Enzyme B-Complex tablets are enteric coated to enhance bioavailability by allowing delivery to intestinal absorption sites intact, unharmed by stomach acids.2 Our Quality department had to qualify several new ingredients for this formula.

This formula is enhanced with added Coenzyme C10 (CoQ10), Alpha Lipoic Acid, Betaine (TMG), Vitamin C, and both coenzyme forms of B-12 (Methylcobalamin and Dibencoside) and is suitable for vegetarians and vegans.

SERVING SIZE & HOW TO TAKE IT: Two tablets daily, preferably in divided doses. This enteric-coated tablet is best to take between meals (one or more hours before a meal or hours after a meal), as it has an acid-resistant coating that dissolves beyond the stomach and needs to transit quickly past the stomach.

COMPLEMENTARY PRODUCTS: Vitamin C, TMG (Betaine), Lecithin (Choline, Inositol)

CAUTIONS: None.

SPECIFIC: Please discuss your use of B-Vitamins with your physician, especially if you are using any medications.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Shils ME, Olson JA, Shike M (eds.) (1994) Modern Nutrition in Health and Disease, Eighth Edition. Chapters 20-26, 28, 30. Lea & Febiger Philadelphia.
2. Chang EB, Sitrin MD, Black DD (1996) Gastrointestinal, Hepatobiliary, and Nutritional Physiology. Chapter 9, Absorption of Water-Soluble Vitamins and Minerals. Lippincott-Ravin, Philadelpia

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Date: October 06, 2005 10:08 PM
Author: Darrell Miller (dm@vitanetonline.com)

Magnesium is a dietary mineral with a wide array of biological activities in the body. Magnesium participates in numerous life-essential processes that occur both inside and outside cells. Magnesium deficiency impacts normal physiologic function on many levels. Adequate magnesium is a fundamental requirement for optimum function of the cardiovascular system, the nervous system and skeletal muscle, as well as the uterus and GI tract. Magnesium deficiency can affect health of the heart, bones and blood vessels and alter blood sugar balance [1].

Magnesium–Important for Everyone, Deficient in Many The average person living in a modern country today very likely consumes less than the optimum amount of magnesium [2]. An abundance of data collected over the last two decades shows a consistent pattern of low magnesium intake in the U.S. This pattern cuts a wide swath across various age-sex groups. The USDA’s Nationwide Food Consumption Survey found that a majority of Americans consumed less than the recommended daily magnesium intake [3]. Twelve age-sex groups were studied and this low magnesium intake was true for all groups except 0 to 5 year olds.

An analysis of the nutrient content of the diets of 7,810 individuals age four and above included magnesium among several nutrients where the amounts supplied by the average diet "were not sufficient to meet recommended standards" [4]. The FDA’s Total Diet study examined the intakes of eleven minerals, including magnesium, among eight age-sex groups. Data was collected four times yearly from 1982 to 1984. Levels of magnesium, calcium, iron, zinc and copper were low for most age-sex groups [5]. Surveys conducted in Europe and in other parts of North America paint a similar picture. Loss of magnesium during food processing is one explanation for this global lack of adequate dietary magnesium [6].

In particular, the elderly may be susceptible to magnesium deficiency for a variety of reasons, including inadequate magnesium intake, poor absorption due to impaired gastrointestinal function and use of drugs such as diuretics that deplete magnesium from the body [7]. It has recently been theorized that magnesium deficiency may contribute to accelerated aging, through effects on the cardiovascular and nervous systems, as well as muscles and the kidneys [8].

Women who take both synthetic estrogen and calcium supplements may be at risk for low blood levels of magnesium [9]. Estrogen promotes the transfer of magnesium from blood to soft–tissues. Low blood magnesium may result if the ratio of calcium to magnesium intake exceeds 4 to 1. Magnesium supplementation is thus advisable for women taking estrogen and calcium.

Young adults are not immune to magnesium deficiency. The University of California’s Bogalusa Heart Study collected nutritional data from a cross-sectional sample of 504 young adults between age 19 and 28 [10]. The reported intake of magnesium, along with several other minerals and vitamins, was below the RDA.

Glycine is a highly effective mineral chelator. This is because it is a low-molecular-weight amino acid, hence is easily transported across the intestinal membrane. A study conducted at Weber State University found this particular magnesium glycinate was absorbed up to four times more effectively than typical magnesium supplements.

Magnesium-the Versatile Mineral

The average adult body contains anywhere from about 21 to 28 grams of magnesium. Approximately 60 percent of the body’s magnesium supply is stored in bone. Soft tissue, such as skeletal muscle, contains 38%, leaving only about 1 to 2% of the total body magnesium content in blood plasma and red blood cells. Magnesium in the body may be bound either to proteins or "anions" (negatively charged substances.) About 55% of the body’s magnesium content is in the "ionic" form, which means it carries an electrical charge. Magnesium ions are "cations," ions that carry a positive charge. In its charged state, magnesium functions as one of the mineral "electrolytes."

Magnesium works as a "co-factor" for over 300 enzymatic reactions in the body. Metabolism uses a phosphate containing molecule called "ATP" as its energy source. Magnesium is required for all reactions involving ATP [11]. ATP supplies the energy for physical activity, by releasing energy stored in "phosphate bonds".

Skeletal and heart muscle use up large amounts of ATP. The energy for muscle contraction is released when one of ATP’s phosphate bonds is broken, in a reaction that produces ADP. Phosphate is added back to ADP, re-forming ATP. ATP also powers the cellular "calcium pump" which allows muscle cells to relax. Because it participates in these ATP-controlled processes, magnesium is vitally important for muscle contraction and relaxation. By controlling the flow of sodium, potassium and calcium in and out of cells, magnesium regulates the function of nerves as well as muscles [12].

Magnesium’s importance for heart health is widely recognized. The heart is the only muscle in the body that generates its own electrical impulses. Through its influence on the heart’s electrical conduction system, magnesium is essential for maintenance of a smooth, regular heartbeat [13]. Magnesium appears to help the heart resist the effects of systemic stress. Magnesium deficiency aggravates cardiac damage due to acute systemic stress (such as caused by infection or trauma), while magnesium supplementation protects the heart against stress [14]. This has been found true even in the absence of an actual magnesium deficit in the body.

Evidence suggests that magnesium may help support mineral bone density in elderly women. In a two-year open, controlled trial, 22 out of a group of 31 postmenopausal women who took daily magnesium supplements showed gains in bone density. A control group of 23 women who declined taking the supplements had decreases in bone density [15]. The dietary intakes of magnesium, potassium, fruit and vegetables are associated with increased bone density in elderly women and men [16]. In an interesting animal study, rats were fed diets with either high or low levels of magnesium. Compared to the high magnesium-fed rats, bone strength and magnesium content of bone decreased in the low-magnesium rats, even though these rats showed no visible signs of magnesium deficiency [17]. While this finding may or may not apply to humans, it raises the possibility that diets supplying low magnesium intakes may contribute to weakening of bone in the elderly.

Maximizing Absorption––Chelated Minerals Explained Mineral absorption occurs mainly in the small intestine. Like any mineral, magnesium may be absorbed as an "ion," a mineral in its elemental state that carries an electric charge. Mineral ions cross the intestinal membrane either through "active transport" by a protein carrier imbedded in the cells lining the membrane inner wall, or by simple diffusion. The magnesium in mineral salts is absorbed in ionic form. However, absorption of ionic minerals can be compromised by any number of factors, including: 1) Low solubility of the starting salt, which inhibits release of the mineral ion, and 2) Binding of the released ion to naturally occurring dietary factors such as phytates, fats and other minerals that form indigestible mineral complexes [18].

A second absorption mechanism has been discovered for minerals. Experiments have shown that minerals chemically bonded to amino acids (building blocks of protein) are absorbed differently from mineral ions. This has given rise to the introduction of "chelated" minerals as dietary supplements. Mineral amino acid chelates consist of a single atom of elemental mineral that is surrounded by two or more amino acid molecules in a stable, ring-like structure.

Unlike mineral salts, which must be digested by stomach acid before the desired mineral portion can be released and absorbed, mineral chelates are not broken down in the stomach or intestines. Instead, chelates cross the intestinal wall intact, carrying the mineral tightly bound and hidden within the amino acid ring. The mineral is then released into the bloodstream for use by the body. Research by pioneers in the field of mineral chelation and human nutrition indicates that the best-absorbed chelates consist of one mineral atom chelated with two amino acids. This form of chelate is called a "di-peptide." Compared to other chelates, di-peptides have the ideal chemical attributes for optimum absorption [19]. Dipeptide chelates demonstrate superior absorption compared to mineral salts. For example, a magnesium di-peptide chelate was shown to be four times better absorbed than magnesium oxide [20].

Consumer Alert! Not all "amino acid chelates" are true chelates. In order for a mineral supplement to qualify as a genuine chelate, it must be carefully processed to ensure the mineral is chemically bonded to the amino acids in a stable molecule with the right characteristics. The magnesium bis-glycinate/lysinate in High Absorption Magnesium is a genuine di-peptide chelate ("bis" means "two"). It has a molecular weight of 324 daltons, considerably lower than the upper limit of 800 daltons stated in the definition of "mineral amino acid chelates" adopted by the National Nutritional Foods Association in 1996 [21].

Bioperine® For Enhanced Absorption Bioperine® is a natural extract derived from black pepper that increases nutrient absorption.* Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine® [22].

Scientific References 1. Abbott, L.R., R., Clinical manifestations of magnesium deficiency. Miner electrolyte Metab, 1993. 19: p. 314-22. 2. Durlach, J., Recommended dietary amounts of magnesium: Mg RDA. Magnesium Research, 1989. 2(3): p. 195-202. 3. Morgan, K.e.a., Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition, 1985. 4: p. 195-206. 4. Windham, C., Wyse, B., Hurst, R. Hansen, R., Consistency of nutrient consumption patterns in the United States. J AM Diet Assoc, 1981. 78(6): p. 587-95. 5. Pennington, J., Mineral content of foods and total diets: the Selected Minerals in Food Survey, 1982 to 1984. J AM Diet Assoc, 1986. 86(7): p. 876-91. 6. Marier, J., Magnesium Content of the Food Supply in the Modern- Day World. Magnesium, 1986. 5: p. 1-8. 7. Costello, R., Moser-Veillon, P., A review of magnesium intake in the elderly. A cause for concern? Magnesium Research, 1992. 5(1): p. 61-67. 8. Durlach, J., et al., Magnesium status and aging: An update. Magnesium Research, 1997. 11(1): p. 25-42. 9. Seelig, M., Increased need for magnesium with the use of combined oestrogen and calcium for osteoporosis treatment. Magnesium Research, 1990. 3(3): p. 197-215. 10. Zive, M., et al., Marginal vitamin and mineral intakes of young adults: the Bogalusa Heart Study. J Adolesc, 1996. 19(1): p. 39-47. 11. McLean, R., Magnesium and its therapeutic uses: A review. American Journal of Medicine, 1994. 96: p. 63-76. 12. Graber, T., Role of magnesium in health and disease. Comprehensive Therapy, 1987. 13(1): p. 29-35. 13. Sueta, C., Patterson, J., Adams, K., Antiarrhythmic action of pharmacological administration of magnesium in heart failure: A critical review of new data. Magnesium Research, 1995. 8(4): p. 389- 401. 14. Classen, H.-G., Systemic stress, magnesium status and cardiovascular damage. Magnesium, 1986. 5: p. 105-110. 15. Stendig-Lindberg, G., Tepper, R., Leichter, I., Trabecular bone density in a two year controlled trial of peroral magnesium in osteoporosis. Magnesium Research, 1993. 6(2): p. 155-63. 16. Tucker, K., et al., Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr, 1999. 69(4): p. 727-736. 17. Heroux, O., Peter, D., Tanner, A., Effect of a chronic suboptimal intake of magnesium on magnesium and calcium content of bone and bone strength of the rat. Can J. Physiol. Pharmacol., 1975. 53: p. 304-310. 18. Pineda, O., Ashmead, H.D., Effectiveness of treatment of irondeficiency anemia in infants and young children with ferrous bisglycinate chelate. Nutrition, 2001. 17: p. 381-84. 19. Adibi, A., Intestinal transport of dipetides in man: Relative importance of hydrolysis and intact absorption. J Clin Invest, 1971. 50: p. 2266-75. 20. Ashmead, H.D., Graff, D., Ashmead, H., Intestinal Absorption of Metal Ions and Chelates. 1985, Springfield, Illinois: Charles C. Thomas. 21. NNFA definition of mineral amino acid chlelates, in NNFA Today. 1996. p. 15. 22. Bioperine-Nature's Bioavailability Enhancing Thermonutrient. 1996, Sabinsa Corporation: Piscataway, N.J.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Doctor's Best•1120 Calle Cordillera•Suite 101, San Clemente, CA 92673

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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=821)

Date: August 20, 2005 11:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Source Naturals - Flawless Finished Goods

The packaging process requires careful coordination from start to finish. All products are meticulously tracked, counted or measured, filled into finished containers, safety-sealed, and assigned identification codes. This ensures the highest quality product – from our facility to the consumer’s hands. -Alex Rosario, Packaging Supervisor

Flawless Finished Goods

Our Packaging Department has final responsibility for seeing that our high quality supplements reach you in a form that ensures safety, freshness and accountability.

Maintaining Freshness Source Naturals takes great care to package our products in a manner that maintains the quality and potency of the ingredients. We print “best if used by” dates on our bottles to let you know they are fresh. To protect certain products from moisture, which can lower tablet potency, desiccants are inserted into bottles. An inner seal provides further protection.

Ensuring Uniform Safety Standards

High-speed tablet counters correctly add the number of tablets to place in each bottle. After bottles are filled, they are capped and pressuresensitive seals are applied to make the product tamper-evident. A full body sleeve is heatshrunk to each bottle, adding a second tamper seal.

Achieving Accountability

Source Naturals traces all material lots used in our products from receipt to finished product. Through careful documentation, we have the ability to track a single ingredient throughout the entire manufacturing process to the completed bottled product. The material number, weight, and lot number of each ingredient are recorded on batch sheets. Each bottle is marked with a unique, traceable manufacturing lot number. This means a bottle can be taken off a store shelf and every ingredient traced back to its source.

Inspecting Finished Products

Our finished goods inspectors follow a very specific set of standards to determine if the finished product can be released for shipping. Our inspectors verify that bottles meet our appearance standards, are appropriately labeled, contain the correct number of tablets, have intact tamper-evident seals and, in the case of products with high iron content, child-resistant caps.

Every ingredient in every product can be traced back to its original source and manufactured lot number.

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Date: July 27, 2005 04:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: An old Indian remedy gives your teeth a new gleam - NEEM

Keen on Neem

An old Indian remedy gives your teeth a new gleam.

The search for clean teeth, healthy gums and fresh breath is not just a modern obsession, but an age-old fixation. Dental historians believe that ancient cavity rates ranged from 1% among Eskimos, with their highly carnivorous diet, to 80% among members of Egypt’s royalty, who feasted on dainties that included many high-carb delights. So it’s no surprise that most ancient cultures had their favorite oral hygiene therapies.

In Indian, the tooth scrubber of popular choice was twigs taken from the neem tree. Small wonder: This tropical evergreen’s therapeutic versatility sports and impressive 4,000-year-old track record, earning it the nickname of “village pharmacy.” Indians who went abroad carried neem with them, and they put the entire tree-bark, fruit, leaf, root, seed-to health-enhancing use. One famous Indian emigrant, Mahatma Gandhi, was a keen neem enthusiast; after returning to his native land, Gandhi held prayer meetings under a neem tree.

Today, neem’s beautiful branches grace a vast swath of the Southern Hemisphere, including Australia (which may become the biggest neem-producing nation over the coming decades), Fiji, sub-Saharan Africa, Central and South America and the Caribbean. This remarkable plant’s Sanskrit name, arista, says it all-“perfect, complete and imperishable.”

Keeping Teeth Intact

Your dentist is actually the second one to drill your pearly whites. The first drillers are the germs that reside in your mouth-or, to be more accurate, the acids these wee beasties produce. Their handiwork: dental caries, or just plain cavities. These bacteria are also responsible for gum disease, which can lead to tooth loss if unchecked. What’s even worse, low-level inflammation caused by disordered gums may create the kind of blood-vessel havoc associated with heart problems.

Neem extracts act against a variety of detrimental microbes, which may explain its time-tested success in helping to keep teeth whole. Scientists at India’s Zydus Research Centre found that individuals who used a neem dental gel twice a day for six weeks enjoyed significant reductions in both plaque-the gummy, bacteria-harboring stuff that accumulates on teeth-and gum disease (International Dental Journal 8/04).

Neem’s fame is spreading among Northern Hemisphere consumers. It is becoming an herbally aware toothpaste ingredient valued for the fresh feeling its cool astringency imparts to the mouth. Neem is also a prized component of other health and beauty products, such as bath powders, lotions, shampoos and soaps.

Ayurvedic Superstar

In India, neem is a vital weapon in the arsenal of Ayurveda, that country’s system of traditional medicine. Practitioners there mash the leaves into a paste to alleviate chickenpox and warts, and brew them into tea to break malaria’s feverish grip. The leaves also make a soothing soak for fungus-infected feet.

Indian scientists are also hard at work studying neem. They’ve distilled the substances that account for neem’s ability to fight bacteria, fungi and parasites (including the pests that infest pets). Researchers have explored neem’s other traditional usages; in one study, a bark extract was able to ease ulcers (Life Sciences 10/29/04). What’s more, neem is esteemed for its contributions to Indian agriculture; the seedcake makes a nutritious feed supplement and bees that feed on neem are free of wax moths.

If you value keeping your teeth in gleaming condition, consider neem.
-Linda James

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Vitanet ®

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Date: July 25, 2005 10:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Progesterone and PMS

Natural Progesterone and PMS

When a woman’s body experiences an imbalance of progesterone resulting in estrogen dominance, a variety of pre-menstrual symptoms can result. Estrogen dominance can occur when a progesterone deficiency is present. PMS refers to a whole host of symptoms which can vary from woman to woman. Conventional therapies for PMS involves the use of antidepressants, diuretics, counseling, nutritional regimens and synthetic hormones. Interestingly, most symptoms which commonly characterize PMS are also typical of estrogen dominance. Due to this observation, Dr. John R. Lee gave natural progesterone to his patients with PMS and obtained some impressive results. “The majority (but not all) of such patients reported remarkable improvement in their symptoms-complex, including the elimination of their premenstrual water retention and weight gain.”10 Let’s quickly review the hormonal flux which characterizes the menstrual cycle. During the week following the end of the menstrual period, estrogen is the dominating hormone which initiates the buildup of the uterine lining once again. At the same time, eggs in the ovary begin to mature. Estrogen levels also contribute to the secretion of more vaginal mucous at this time making the tissue environment more conducive to sperm survival and motility. From ten to twelve days after the beginning of the last period, estrogen levels will crest and then begin to taper just prior to ovulation and when the egg (corpus luteum) has matured enough to produce progesterone.

Consequently, progesterone will dominate during the second half of the cycle. Increased levels of progesterone cause the body temperature to rise, the continued development of the uterine blood-filled lining, and the thinning of cervical secretions. All of these events occur in anticipation of the presence of a fertilized egg. If pregnancy does not occur within 10 to 12 days after ovulation, both estrogen and progesterone levels rapidly fall, which initiates the shedding of the uterine lining (menstruation) and a new cycle begins again. If a woman becomes pregnant, progesterone levels continue to rise and the uterine lining remains intact to receive and nourish the fertilized egg.

Eventually the placenta will produce much higher than normal amounts of progesterone throughout the remainder of the pregnancy. It’s rather easy to see that a woman’s monthly cycle is regulated by the rise and fall of estrogen and progesterone. This perfectly natural fluctuation of hormones can wreak havoc with the health of a woman when imbalances occur. More often than not, a hormonal imbalance consists of a progesterone deficiency. Progesterone was designed by nature to inhibit many of the negative effects of estrogen. If progesterone levels do not balance out estrogen during the last two weeks of the cycle, PMS can become a problem. Dr. Lee illustrates this, saying: “A surplus of estrogen or a deficiency of progesterone during these two weeks allows for an abnormal month-long exposure to estrogen dominance, setting the stage for the symptoms of estrogen side effects.”11

Clearly, natural progesterone may be one of the most, if not the most effective, therapies to deal with PMS miseries. Unfortunately, many women are completely unaware of its action or availability.

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Date: June 29, 2005 05:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bio-Chelation

Bio-Chelation* By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt In The Beginning The Bio-Chelated¨ process describes a proprietary cold extraction technique developed by Mr. Frank D'Amelio Sr., founder and owner of Nature's Answer¨, and well- respected author*. Long before Nature's Answer¨ was formed (early 1970's), Mr. D'Amelio was immersed in the study of botanical medicine, researching the various herbal texts including the national USP/N.F. (United States Pharmacopeia/National Formularies) dating back to the mid -1800's. (The USP/N.F. is a reference source that provides manufacturing standards and extraction techniques used to make herbal formulas; these standards were considered official prior to 1938.) This authoritative formulary discussed the use of plant parts such as leaf, stem, bark, flowers and roots. It recommended certain solvents known as "menstruums", in which plant parts were soaked in order to extract their active constituents. High heat was also often utilized to concentrate the extract. Mr. D'Amelio noticed that high amounts of solvents, usually alcohol, were often recommended, and that sediment would fall to the bottom (precipitate) in certain solutions. He began to investigate how he could offer the consumer potent herbal products made with very low heat, with minimum precipitation, and without a lot of alcohol!

A Clue From Nature In working towards the goal of attaining a final botanical extract product with little alcohol, Mr. D'Amelio turned to Nature for the apparent answer. He realized that plants were composed of 80-85% water as well as some alcohols, fats, etc. If plants were able to keep the active constituents in solution and use them as needed mainly through water, not alcohol or other solvents, why couldn't he? Thus, he began a long, in-depth series of experiments with many different plants. Through rigorous research protocols and scientific testing, he discovered that the active constituents of some plants could be extracted using lower alcohol amounts with water and other natural solvents such as organic apple cider vinegar or vegetable glycerine. At other times, however, higher alcohol was necessary, such as when he was extracting volatile oils like menthol from peppermint. The experimentation process continued, with Mr. D'Amelio documenting the optimum menstruum combinations required for each plant to yield the maximum beneficial components. (Note that there are differences in alcohol. The alcohol consumed in wine and beer is derived through a natural fermentation process with no processing other than filtration. When distilled alcohol is added to an extraction, which some herbal manufacturers use, it effects the body in a more detrimental way; thus the development of the Bio-Chelation¨ process, which uses only organic alcohol).

The Bio-Chelated¨ Method Is Developed As Mr. D'Amelio continued his experimentation with various plants and menstruums, his extraction processes became more refined, and eventually led to the development of the Bio-Chelated¨ method. The Bio-Chelated¨ method incorporates soaking for a period of time, using different menstruum ratios for different plants to optimize their therapeutic values. Furthermore, this procedure offers additional significant advantages when compared with other types of extraction processes commonly employed by competitors in the herbal industry.

Bio-Chelation includes the use of "cold extraction", where the plant parts are extracted without being exposed to excessive amounts of heat. Cold extraction helps the herb maintain vital minerals and other trace elements in solution, thus enabling the herb to keep its Holistic Balanceª intact. (Holistic Balanceª means that extracts retain as many of the natural constituents of the original plant as possible.) In addition, the Bio-Chelated¨ process incorporates the use of an exclusive technique that removes much of the alcohol used during the menstruum soaking (maceration) phase, replacing it with vegetable glycerin instead. The resulting yield is an herbal extract that is either alcohol-free, or has a low alcohol content. (Both alcohol-free and low alcohol products from Nature's Answer feature vegetable glycerin only. Glycerin is used because it helps bind certain plant constituents, is natural to the body, is easily absorbed by the cells and has little insulin response. Only vegetable glycerin has been used since 1972. In addition, all alcohol used in Nature's Answer's low alcohol formulas is certified organic.)

The Bio-Chelated¨ method was the first extraction process to yield a 12-14% alcohol extract in the herbal industry!

Nature's Answer Stands The Test of Time Over the last quarter of a century (since 1972), the Bio-Chelated¨ cold extraction process has been painstakingly tested and proven to stand the test of time. Incorporating Mr. D'Amelio's proprietary cold extraction process in today's manufacturing procedures continues to yield a measurably superior product. One such example is Saw Palmetto from Nature's Answer¨, a product that is produced utilizing our Bio-Chelated¨ method versus the more expensive CO2 method. Our Bio-Chelated¨, cold extraction process yields a product that not only contains the same amounts of active constituents as the more expensive CO2 extracted product, but features a higher percentage of polyphenols, the compounds responsible for the herb's antioxidant properties. The end result is a Saw Palmetto extract that maintains its holistic balance! (Note that most prior successful studies done on Saw Palmetto utilized grain alcohol extracts which contained naturally occurring polyphenols; the CO2 extracted products do not contain polyphenols!) Although larger quantities of herbal products are now being produced as compared to the earlier experimental batches made by Frank D'Amelio, his founding corporate philosophy remains intact - combine the greatest care with the highest quality of raw material to create the ultimate herbal extract that works. After all, that's what it's all about, isn't it? Bio-Chelated¨..Another reason to count on Nature's Answer Without Question! Manufacturing Highlights:

State-of-The-Art Laboratory Manufacturing Equipment HPLC, UV, IR, GC/MS, LC/MS, TOC and Densitometer 316 Pharmaceutical Grade Stainless Steel or Glass Lined Extraction Vessels (instead of the inexpensive, more commonly used plastic or polyethylene extraction vessels; these vessels are porous and may contain microorganisms, residual plasticizers that are difficult to clean and could cross contaminate different batches of herbs) FDA Registered & Pharmaceutically Licensed cGMP and SOP Compliant Manufactured in the U.S.A. *Botanicals - A Phytocosmetic Desk Reference (1999), Botanical & Herbal Folklore (1974), The Botanical Practitioner (1978) Bio-Chelated¨ is a registered trademark of Bio-Botanica Inc.¨ Holistic Balanceª is a trademark of Bio-Botanica Inc.¨

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Date: June 14, 2005 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Your Healthy Harvest

Your Healthy Harvest by Marjorie Flakowitz Energy Times, August 15, 2004

Once frowned on by conventional farmers, organic food has won respect from everyone concerned about the health of both the earth and the people who inhabit it.

Today, organic farming is considered one of the most rapidly growing areas of American agriculture. Organic foods sales topped $9 billion in 2002 and grew about 20%, up to almost $11 billion in 2003 (Organic Trade Association).

So when you buy organic, you join an expanding market that takes advantage of great-tasting, good-for-you food. Long ago, when the practice of farming was first devised, all farming was organic farming. So today's organic movement is bringing farming back to its roots.

But, safe to say, that is not what's motivating most consumers. A main reason for the popularity of organic food derives from the reassurance that organic foods, raised without artificial chemicals and pesticides, cut your exposure to toxic residues. A growing body of research shows organic food is richer in beneficial natural substances, too.

" Organic food and organic farming represent a philosophy that goes beyond just the quality of the food," says Steve Meyerowitz in The Organic Food Guide (Globe Pequot). "It strives to maintain the integrity of the entire food chain-plants, soil, air, water, animals and people. We are all part of the same ecosystem."

By eating organic, you eliminate pollution both from your body and the earth. Because our bodies are made of the animal and plant products we consume, our internal, physiological ecosystem and the earth's environment are inexorably entwined.

Chilling Arctic Evidence

As evidence of this connection, consider what's happened in the Arctic. Researchers who have analyzed Arctic water, ice, snow, soil and plants have found that chemicals used in farming and industry in other parts of the world have traveled north and accumulated in alarming quantity. How and if these chemicals break down depends on sunlight and the amount of organic matter contained in Arctic waters (American Chemical Society, 9/11/03).

" Once pollutants enter the water column, their behavior is poorly understood-particularly the processes that govern their lifetime and concentrations," says Amanda Grannas, PhD, a researcher at Ohio State University. "Such pollutants are now being found in wildlife, from fish to seals to whales, and even in people living in the Arctic."

Dr. Grannas and others looked at the pesticides lindane and hexachlorobenzene (HCB), two chemicals that have migrated to Arctic waters. Lindane is used by American farmers to treat seeds before they are planted. HCB, banned in the US in 1984, is still used in other countries to protect wheat from fungus.

The scientists found that sunlight at the top of Arctic waterways can help break down some pesticides. At lower depths, however, cut off from the sun's rays, pesticides can remain largely intact. In this research, lindane proved to persist much more readily than HCB.

" Lindane is one of the most persistent of pollutants," warns Dr. Grannas. "This could be because it's photochemically inert, whereas pollutants like HCB degrade relatively quickly. The main message is that pollutants can behave quite differently. These pollutants already affect local ecosystems, and could have repercussions for human health."

Organics Means More Benefits

Researchers are also finding that organic produce contains larger quantities of beneficial natural chemicals. For instance, one study (Journal of Agriculture and Food Chemistry 2/26/03) showed that berries and corn grown organically can have almost 60% more polyphenolics. Polyphenolics are antioxidants plants use for protection against disease and which are good for humans. Researchers believe that when crops are grown conventionally, protected by pesticides and herbicides, they produce fewer of these substances. " This really opens the door to more research in this area," says Alyson Mitchell, PhD, assistant professor of food science at University of California at Davis, who led the research.

These scientists compared levels of total polyphenolics and vitamin C content in marionberries (a type of blackberry) and corn grown organically, sustainably or conventionally, and also looked at chemicals in strawberries grown either sustainably or conventionally. (Sustainable farming falls between the organic and conventional methods, and concentrates on farming that's self-sufficient-for example, feeding cows hay you've grown yourself, and then using the cows' manure to fertilize another crop.) They found that organic marionberries and corn had 50% to 58% more polyphenolics. The sustainably grown strawberries had 19% more polyphenolics. And all the organic produce contained more vitamin C.

Self-Defense for Plants

According to Dr. Mitchell, the organic crops contained the high levels of polyphenolics you'd expect to find in wild plants, suggesting that, on conventional farms, pesticides reduce the necessity for plants to make these protective, natural chemicals. " If an aphid is nibbling on a leaf, the plant produces phenolics to defend itself," she says. "[P]henolics guard the plant against these pests."

Pesticides kill insects like aphids and thereby reduce the antioxidants produced by the plant. " This helps explain why the level of antioxidants is so much higher in organically grown food," Mitchell says. "By synthetically protecting the produce from these pests, we decrease their need to produce antioxidants. It suggests that maybe we are doing something to our food inadvertently.

" We know [polyphenolics] are beneficial [to human health], but we don't know what types of polyphenolics are beneficial, or in what quantities," Dr. Mitchell notes. " Originally, the question was just really intriguing to me. I found that the higher level of antioxidants is enough to have a significant impact on health and nutrition, and it's definitely changed the way I think about my food."

Vitamin C in Oranges

Meanwhile, nutritional research on the vitamin C in oranges turns up similar results: organic oranges are richer in this antioxidant nutrient than conventionally grown oranges (Great Lakes Regional Meeting, American Chemical Society, 6/2/02).

The more common supermarket oranges are significantly larger than organically grown oranges, and they have a deeper orange color. Because of their larger size, "we were expecting twice as much vitamin C in the conventional oranges," says Theo Clark, PhD, chemistry professor at Truman State University in Kirksville, Missouri.

But when he isolated the chemicals in the oranges and further refined his search with nuclear magnetic resonance (NMR), spectroscopy demonstrated that organically grown oranges possess 30% more vitamin C than the conventionally grown fruits-even though they are only about half as large.

Dr. Clark isn't sure why organic oranges are richer in vitamin C, but he says, "...[W]e speculate that with conventional oranges, [farmers] use nitrogen fertilizers that cause an uptake of more water, so it sort of dilutes the orange. You get a great big orange but it is full of water and does not have as much nutritional value.

" However, we can only speculate. Other factors such as maturity, climate, processing factors, packaging and storage conditions require consideration." Along with analyzing oranges, Dr. Clark and his research team questioned about 70 people to measure their concept of the nutritional value of organic oranges. In this survey, 85% of the respondents thought that organic oranges have a higher nutritional content than conventionally grown fruit.

Dr. Clark's laboratory work shows that "they were right on." In Dr. Clark's view, these issues are important because consumers have a right to know the real nutritional content of organic produce, and the fact that analyses show that organic fruit has much more vitamin C validates the benefits of eating organic.

Defense Mechanism

Both plants and animals protect themselves from disease with many of the same chemicals. The natural substances that, in a farmer's field, defend vegetables from insects and microbes before they are harvested for your dinner go to work defending your body after you eat and digest them.

When you eat organic you bolster your health with more of these natural wonders. No wonder organic is becoming so popular!

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Date: May 23, 2005 09:11 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Resveratrol - support for healthy cardiovascular health

The following abstract proved that Resveratrol improves cardiovascular health:

Mechanisms of Cardiovascular Protection by Resveratrol. Hao, Han Dong; He, Li Ren. Postgraduate School, Shanghai University of Traditional Chinese Medicine, Peop. Rep. China. Journal of Medicinal Food (2004), 7(3), 290-298. CODEN: JMFOFJ ISSN: 1096-620X. Journal; General Review written in English. CAN 142:147537 AN 2004:763821 CAPLUS

Abstract

A review. The phytoantitoxin resveratrol is a plant-derived polyphenol with phytoestrogenic properties. Resveratrol protects the cardiovascular system by mechanisms that include defense against ischemic-reperfusion injury, promotion of vasorelaxation, protection and maintenance of intact endothelium, anti-atherosclerotic properties, inhibition of low-d. lipoprotein oxidn., suppression of platelet aggregation, and estrogen-like actions.

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Date: May 20, 2005 12:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Sytrinol -- Natures way to lowering cholesterol up to 40%

In a Lab experiment, cholesterol was lowered by 40%

Abstract

Formulations contg. citrus polymethoxylated flavones (PMF), mainly tangeretin, or citrus flavanone glucosides hesperidin and naringin were evaluated for blood cholesterol-lowering potential in hamsters with diet-induced hypercholesterolemia. PMF metabolites were also investigated. Diets contg. 1% PMF decreased blood serum total and very-low-d. lipoprotein (VLDL) + LDL cholesterol by 19-27 and 32-40%, resp., and decreased serum triacylglycerol levels. Comparable decreases were achieved by feeding 3% mixt. of hesperidin and naringin (1:1), implying lower hypolipidemic potency of the hesperidin/naringin mixt. vs. PMF. HPLC-MS anal. identified high blood serum, liver, and urine concns. of tangeretin metabolites, including dihydroxytrimethoxyflavone and monohydroxytetramethoxyflavone glucuronides and aglycons. The total liver concns. of tangeretin derivs. corresponded to hypolipidemic concns. of intact tangeretin in earlier expts. in vitro. PMF may be novel flavonoids with cholesterol- and triacylglycerol-lowering potential. Elevated liver levels of PMF metabolites may be directly responsible for their hypolipidemic effects in vivo.

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Date: May 12, 2005 12:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Garlic Extract Modulation or Pulmonary Vascular Function:

Garlic Extract Modulation or Pulmonary Vascular Function: Comparisons Among Fresh, Aged, Freeze-dried Powder and Oil Macerate

Author:
Ku DD, Abdel-Razek TT, Dai J, Fallon MB, Abrams GA

Source:
FASEB Journal, 1998

Abstract:
Garlic has been advocated for a variety of therapeutic applications including pulmonary vasodiladon, but definitive experimental evidence supporting these claims remain inconclusive. We compared the relative vasorelaxation efficacv of fresh garlic extract (FG) to those commercially packaged garlics on rat pulmonary artery (PA) rings. Water extract of fresh whole garlic (1-500 µg/ml) produced a dose-dependent relaxation in endothelium (EC)-intact (PA, reaching a maximum of -62±4% (M±SE of 18 rings). Maximum relaxation observed with the garlic storage leaves (-79.±4%, n=16 rings) was significantly higher than the garlic inner stem (-48±5%, n=12 rings). Boiling of garlic extracts at l00ºC for 30 mins reduced the relaxation by 10-20%. Mechanical disruption of EC or pretreatment with L-NAME, reduced the relaxation by 30-40%. Extracts from freeze-dried powder (Garliquc; Pure-Gar and Kwai), aged garlic (Garlique), and garlic oil macerate (Softgel) resulted in -87±3% (n=16 rings), -72±6% (n=30 rings), -45±3% (n=30 rings), -22±5% (n=14 rings) and -5±3% (n=14 rings relaxation, respectively. Vasoinhibitory effect of FG extract was readily reversible upon washing, whereas the Pure-Gar and Garlique effects tended to be longer lasting and PA contractile response remained depressed even after 60-min washing. These results show that extracts of both fresh and freeze-dried garlic, but not the oil macerate, are capable eliciting both EC-dependent and -independent relaxation in rat PA. Differences in vasorelaxant potency may be related to the concentrations of the garlic active ingredient, allicin, in different garlic preparations.

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Date: May 12, 2005 12:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Garlic Elicits a Nitric Oxide-Dependent Relaxation and...

Garlic Elicits a Nitric Oxide-Dependent Relaxation and Inhibits Hypoxic Pulmonary Vasoconstriction in rats.

Author:
Kim-Park S, Ku DD.

Source:
Clin Exp Pharmacol Physiol 2000 Oct;27(10):780-786.

Abstract:

1. The aims of the present study were to determine the characteristics of garlic extract-induced relaxation in rat isolated pulmonary arteries, its susceptibility to changes in oxygen tension and its protective effect against hypoxic pulmonary vasoconstriction.

2. In normoxia, garlic extract (3-500 µ/mL) produced a dose- and nitric oxide (NO)-dependent relaxation. Following 60 min hypoxia, maximum garlic relaxation was reduced compared with control (mean (-SEM) -86 +/- 3 vs-69 +/- 2% of phenylephrine (PE) precontraction, respectively), but recovered after 60 min reoxygenation (-85 +/- 3% PE precontraction).

3. Acetylcholine (0.1 micromol/L)-induced NO-dependent relaxation was reduced from a control value of -76 +/- 1% to -46 +/- 4% during hypoxia and was further reduced to -35 +/- 2 % after reoxygenation.

4. In endothelium-intact arteries, hypoxic exposure resulted in a triphasic response: early transient contraction (+24 +/- 4%), followed by transient relaxation (-37 +/- 7%) and then sustained contraction (+62 +/- 5%).

5. Pretreatment with NG-nitro-L-arginine methyl ester abolished the early transient contraction, moderately attenuated the sustained contraction and had no effect on the transient relaxation. Mechanical endothelial disruption inhibited all hypoxia-induced vascular changes.

6. Garlic pretreatment had no effect on the early transient contraction (+25 +/- 4%), but inhibited the transient relaxation (-5 +/- 3%; P < 0.05) and the sustained contraction (+26 +/- 5%;P < 0.05).

7. Garlic also significantly inhibited endothelin-l-induced contractions in a dose-dependent manner.

8. These findings show that garlic extract modulates the production and function of both endothelium-derived relaxing and constricting factors and this may contribute to its protective effect against hypoxic pulmonary vasoconstriction.
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Date: May 12, 2005 10:00 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Under-Reported (and Underappreciated) Cholesterol control.

Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Control

Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat.

The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol.

Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid.

The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.)

Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them.

Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established.

How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a closer look.

Gugulipid

In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides.

Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels."

Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions.

Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state.

Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves.

Pantethine

Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6

Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels.

Niacin

When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long.

There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12

Tocotrienols

We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health.

Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger.

The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E."

It would be a tremendous service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E.

References

1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.

2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18.

3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.

4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.

5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.

6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86.

7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980.

8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45.

9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93.

10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26.

11. Welsh, A.L. Ede, M. Inositol hexanicotinate for improved nicotinic acid therapy. International Record of Food Medicine 1961;174(1):9-15.

12. "Inositol hexaniacinate" (Monograph). Alternative Medicine Review 1998;3(3):222-3.

13. Serbinova, E., et. al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha tocotrienol. Free Radical Biology and Medicine 1991;10:263-275.

14. Qureshi, N. Qureshi, A.A. Tocotrienols: Novel Hypercholesterolemic Agents with Antioxidant Properties. in 'Vitamin E in Health and Disease' Lester Packer and Jürgen Fuchs, Editors. 1993; New York: Marcel Dekker, Inc.

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