Search Term: " Pumps "

	Fitness and Its Role in Beauty: Unlocking the Secrets to Glowing Skin and Well-being	Darrell Miller	6/1/24
	Introducing the Now Foods Bakuchiol Skin Renewal Serum for Fine Lines and Wrinkles!	Darrell Miller	9/10/22
	Increase circulation naturally with L-arginine and L-citrulline	Darrell Miller	9/7/22
	Tea drinkers can take comfort in new study about heart benefits	Darrell Miller	5/12/17
	Vitamin D Pumps Up Muscles	Darrell Miller	2/18/17
	How vitamins help lower blood pressure naturally	Darrell Miller	12/8/13
	How vitamins help lower blood pressure naturally	Darrell Miller	12/8/13
	How to manage high blood pressure with herbs and vitamins	Darrell Miller	2/20/12
	How Can I Raise Blood Pressure Naturally?	Darrell Miller	10/18/11
	Regulating Blood Pressure Naturally	Darrell Miller	3/28/07
	Pain - Post Op and Relaxation	Darrell Miller	7/13/05
	GARLIC IS A POWERFUL DETOXIFIER	Darrell Miller	6/25/05
	Garlic for the Ages - eat garlic because it's good for your heart...	Darrell Miller	6/13/05
	Higher Mind - Smart Nutrients for the Performance of a Lifetime...	Darrell Miller	6/2/05
	Heart Science - A Five-Tiered Approach to Heart Health ...	Darrell Miller	6/2/05
	COENZYME Q10 - Transforming food into energy	Darrell Miller	6/1/05

Date: June 01, 2024 10:58 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Fitness and Its Role in Beauty: Unlocking the Secrets to Glowing Skin and Well-being

Fitness and Its Role in Beauty: Unlocking the Secrets to Glowing Skin and Well-being

In the quest for beauty, many often look to skincare products and treatments, yet one of the most effective pathways to radiant skin and overall health is through regular physical activity. Exercise offers an array of benefits that enhance beauty from within, contributing to healthy skin, a glowing complexion, and a fit physique. This article explores how fitness plays a crucial role in beauty and well-being, suggests exercise routines that promote beauty from within, and recommends a supplement to boost hair and skin health.

The Connection Between Fitness and Beauty

Improved Circulation

When you engage in physical activity, your heart Pumps more blood, increasing circulation throughout the body. This enhanced blood flow delivers essential nutrients and oxygen to your skin cells, promoting cell regeneration and elasticity. Improved circulation also assists in flushing out toxins, contributing to clearer and more vibrant skin.

Reduction of Stress

Stress is a significant contributor to numerous skin concerns such as acne, eczema, and psoriasis. Regular exercise can help reduce stress by releasing endorphins, the body's natural mood enhancers. Lower stress levels can result in fewer breakouts and a reduction in skin flare-ups, ultimately leading to a more serene and healthy appearance.

Enhanced Skin Detoxification

Engaging in activities that make you sweat, such as running, cycling, or hot arobics, can help detoxify your skin. Sweating helps to open up pores and remove dirt and impurities, giving your skin a natural detox. Remember to cleanse your face thoroughly after sweating to prevent any potential buildup of bacteria.

Collagen Production

Exercise helps to boost collagen production, a protein that maintains skin's firmness and elasticity. High-intensity workouts and strength training, in particular, can stimulate collagen synthesis, leading to tighter, more youthful-looking skin.

Better Sleep

Regular exercise can improve your sleep patterns, which in turn benefits your skin. During deep sleep, the body works to repair and regenerate cells, including skin cells. Better sleep can result in fewer dark circles, reduced eye puffiness, and a more rested appearance overall.

Balanced Hormones

Hormonal imbalances can cause various skin problems, including acne and premature aging. Exercise helps regulate hormones, stabilizing levels of cortisol, estrogen, and testosterone, which are crucial for maintaining healthy skin.

Exercise Routines That Promote Beauty from Within

Cardiovascular Exercises

Running and Jogging

Running and jogging are excellent ways to boost circulation, enhance cardiovascular health, and induce sweating, which can help detoxify the skin.

Cycling

Cycling, whether outdoors or on a stationary bike, improves blood flow to the skin, reduces stress, and can be a fun way to stay active.

Swimming

Swimming is a low-impact exercise that increases circulation, tones muscles, and has the added benefit of keeping skin hydrated due to the water environment.

Strength Training

Weightlifting

Incorporating weightlifting into your routine can boost collagen production and improve skin elasticity. Focus on compound movements like squats, deadlifts, and bench presses for maximum effect.

Resistance Band Exercises

Using resistance bands can help build muscle and enhance circulation without putting too much strain on your joints. These exercises are great for improving muscle tone and skin firmness.

Mind-Body Workouts

Arobics

Arobics not only improves flexibility and muscle tone but also reduces stress and promotes a better sleep cycle, which are all beneficial for your skin. Floor leg lifts with dumbells and crunches and lateral lifts on the floor can increase blood flow to the face, enhancing your complexion.

Pilates

Pilates focuses on core strength, posture, and flexibility. The controlled movements and emphasis on breathing can improve circulation and reduce stress, contributing to overall skin health.

Tai Chi

Tai Chi is a gentle form of martial arts that reduces stress, improves flexibility, and enhances balance. It’s an excellent way for people of all ages to promote overall well-being and skin health.

High-Intensity Interval Training (HIIT)

HIIT workouts involve short bursts of intense exercise followed by rest periods. This type of training is highly effective for boosting metabolism, increasing collagen production, and promoting healthy, radiant skin. Exercises like burpees, jump squats, and sprinting can be incorporated into a HIIT routine.

Enhancing Beauty Through Nutrition: Supplements for Hair and Skin Health

Understanding the Importance of Supplements

While a balanced diet and regular exercise are vital for maintaining healthy skin and hair, supplements can provide an additional boost. Nutritional supplements can fill in dietary gaps, ensuring that your body gets the essential vitamins and minerals it needs to support glowing skin and strong, vibrant hair.

Recommended Supplement: Biotin and Collagen Complex

Biotin

Biotin, also known as Vitamin B7, is crucial for hair and skin health. It supports the structure of keratin, a protein that makes up your hair, skin, and nails. Regular intake of biotin can help reduce hair loss, strengthen nails, and improve skin's overall appearance.

Collagen

Collagen is a protein that provides structure and elasticity to your skin. As we age, collagen production decreases, leading to wrinkles and saggy skin. A collagen supplement can help replenish this essential protein, promoting firm, youthful-looking skin.

Combining Biotin and Collagen

For optimal results, opt for a supplement that combines both biotin and collagen. This combination can provide comprehensive support for your beauty regimen, enhancing skin elasticity and hydrating hair follicles from within.

Tips for Choosing the Right Supplement

When selecting a supplement, look for products that are:

• Clinically Tested: Ensure the product has undergone rigorous testing for safety and efficacy.
• High-Quality Ingredients: Choose supplements made with natural, high-quality ingredients.
• Free from Fillers: Avoid products with unnecessary additives, preservatives, or fillers.
• Transparent Labeling: Check for clear labeling about ingredient sources and concentrations.

Incorporating Supplements into Your Routine

Take your supplement consistently, as directed by the packaging, to see the best results. It's also beneficial to combine your supplement intake with a balanced diet rich in fruits, vegetables, lean proteins, and healthy fats.

Ready to Make a Change in Your Hair & Skin?

Integrating regular physical activity into your lifestyle is a powerful way to achieve glowing skin and overall well-being. From improved circulation to reduced stress, the benefits of exercise extend beyond physical fitness, promoting beauty from within. By incorporating a mix of cardiovascular exercises, strength training, and mind-body workouts, you can enhance your natural radiance.

Additionally, supporting your fitness routine with a biotin and collagen supplement can provide further benefits for your hair and skin health. Remember, beauty is not just skin deep—it’s a reflection of a healthy, balanced lifestyle.

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Date: September 10, 2022 09:42 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Introducing the Now Foods Bakuchiol Skin Renewal Serum for Fine Lines and Wrinkles!

Have you ever wished you could turn back the clock on your skin? If so, you're in luck! The Now Foods Bakuchiol Skin Renewal Serum is a plant-based retinol-alternative serum that contains clinically-tested bakuchiol and Pycnogenol to help gently combat the appearance of imperfections and wrinkles. This beauty renewing formula moisturizes and refines for visibly younger-looking skin. Keep reading to learn more about this amazing product!

What is Bakuchiol?

Bakuchiol is a plant-based compound that has been used medicinally for centuries. It is extracted from the seeds and leaves of the babchi plant, also known as Psoralea corylifolia. Bakuchiol has traditionally been used to treat a variety of skin conditions, such as eczema, psoriasis, and acne. More recently, it has gained popularity for its anti-aging properties.

How Does Bakuchiol Work?

Bakuchiol works by mimicking the effects of retinol, a vitamin A derivative that is commonly used in anti-aging products. Retinol works by stimulating collagen production and cell turnover, which helps to reduce the appearance of fine lines and wrinkles. However, retinol can also cause irritation, redness, and dryness, especially if you have sensitive skin. That's where bakuchiol comes in! Bakuchiol has been shown to provide many of the same benefits as retinol without causing irritation.

What are the Benefits of Bakuchiol?

In addition to reducing the appearance of fine lines and wrinkles, bakuchiol has also been shown to improve skin elasticity and firmness. It can also help to even out skin tone and texture. If you're looking for an anti-aging product that won't irritate your skin, bakuchiol is a great option!

The Now Foods Bakuchiol Skin Renewal Serum contains clinically-tested bakuchiol along with other naturally derived ingredients to help reduce the appearance of fine lines and wrinkles. It also contains Pycnogenol®, a patents pending ingredient derived from French maritime pine bark extract that helps improve skin firmness and elasticity while providing antioxidant protection against environmental stressors. The lightweight formula absorbs quickly into the skin without leaving behind any greasy residue. For best results, apply 1-2 Pumps to clean skin every morning and evening.

In Summary:

If you're looking for an anti-aging serum that won't irritate your skin, look no further than the Now Foods Bakuchiol Skin Renewal Serum! This lightweight serum contains clinically-tested bakuchiol along with other naturally derived ingredients to help reduce the appearance of fine lines and wrinkles while improving skin firmness and elasticity. For best results, apply 1-2 Pumps to clean skin every morning and evening. Trust us, your skin will thank you!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6437)

Date: September 07, 2022 03:09 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Increase circulation naturally with L-arginine and L-citrulline

How to Increase Circulation and Nitric Oxide Production with L-arginine and L-citrulline

Do you want to improve your circulation and nitric oxide production? If so, you may want to consider taking L-arginine and L-citrulline together. These two nutrients can work together to help increase NO levels in the body, leading to better blood flow and overall health. In this article, we will discuss the benefits of these two nutrients and how they can help improve your health!

Why is circulation so important?

Circulation is one of the most important functions of the human body. It is responsible for delivering oxygen and nutrients to cells, and for removing waste products. Without adequate circulation, cells would quickly become damaged or die. The circulatory system consists of the heart, blood vessels, and blood. The heart Pumps blood through the vessels, which carry it to different parts of the body. The blood contains oxygen and nutrients that are essential for cell health. Waste products are also carried away in the blood so that they can be eliminated from the body. Because circulation is so important, it is essential to keep the heart healthy. Regular exercise and a healthy diet can help to promote good circulation by keeping the heart muscle strong and functional. Additionally, consume foods and supplements that can boost Nitric Oxide (NO) in the blood stream, avoiding tobacco use and managing stress levels can also help to keep the circulatory system functioning properly.

How does Nitric Oxide (NO) improve circulation?

Nitric oxide is a gas that is produced naturally by the body. In addition to being an important component of cell communication, nitric oxide also has several other important functions, including regulating blood pressure and improving circulation. When it comes to circulation, nitric oxide works by relaxing the smooth muscle cells in the walls of blood vessels. This allows the vessels to widen, which increases blood flow and lowers blood pressure. In addition, nitric oxide helps to prevent platelets from sticking together, which reduces the risk of clot formation. As a result, nitric oxide plays a vital role in maintaining healthy circulation.

What are L-arginine and L-citrulline and what do they do for the body?

L-arginine and L-citrulline are amino acids that are important for the body in many ways. L-arginine helps the body to make nitric oxide, which is a molecule that helps to relax blood vessels. This can help to improve blood flow and reduce blood pressure. L-citrulline, on the other hand, helps to remove ammonia from the body. Ammonia is a waste product that can build up in the blood and cause fatigue. Citrulline also helps to improve blood flow by increasing the production of nitric oxide. In addition, citrulline has been shown to boost levels of energy and stamina. These amino acids are important for many functions in the body and can help to improve overall health.

What are the benefits of improved circulation and NO production?

There are many benefits to improved circulation and NO production. Improved circulation can help more nutrients get to the cells, which helps the body to function better. In addition, NO production can help to improve blood flow, reduce inflammation, and protect against free radical damage. As a result, improving circulation and NO production can have a positive impact on overall health.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6434)

Date: May 12, 2017 06:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Tea drinkers can take comfort in new study about heart benefits

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Date: February 18, 2017 05:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamin D Pumps Up Muscles

It turns out that Vitamin D Pumps up muscles. People that have higher active levels of the vitamin in the bloodstream had more muscle mass. This was found in a study. Researchers looked at multiple forms of Vitamin D in the study and found a very complex relationship than was thought previously.

Vitamin D Pumps Up Muscles

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Date: December 08, 2013 11:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How vitamins help lower blood pressure naturally

Blood Pressure

Blood pressure can be described as the force of blood as it goes through or Pumps in your blood vessels while circulating throughout your body. Those who have narrow arteries normally have a higher blood pressure, because the blood needs to be pumped much harder through their smaller passage-ways. Generally, high blood-pressure is usually caused by too much exercise or stress, but there are some people who may have chronic high blood-pressure. High blood-pressure symptoms can include; headaches, dizziness, and sometimes even nosebleeds. There are situations when there are no any symptoms and you won't know you've any problem until you get a stroke or have a heart attack, and this is why it's important for you to get your blood pressure checked regularly.

Below are some vitamins one can use to naturally lower their blood pressure:

Vitamin A

Vitamin A is a fat soluble which works primarily in body fat tissues. It prevents the LDL cholesterol and also prevents the build up of any plaque on your body's arteries. It can at times be quite toxic if you take too much of it, the recommended amount is only up to 5,000-IUs a day.

Vitamin C
Vitamin C will help in lowering and controlling your body's blood pressure in many ways. It will reduce the generation of all free radicals which can damage the artery walls. It will also help in fixing any damaged blood arteries, and will help elevate the levels of the HDL-cholesterol. If you happen to suffer from high blood-pressure, you should take a minimum of about 2,500-milligrams of vitamin-C every day. Vitamin C rich-foods can include; Oranges, red bell peppers, grape fruit,spinach, and tomatoes.

Vitamin E
Vitamin E will reduce the risk of suffering from heart disease and will also lower your blood pressure. Vitamin E will help protect your arteries from all effects of the LDL cholesterol. It's the most active anti-oxidant in the body. It's recommended you take up to 800 international units (IUs) of all natural vitamin E every day if you have a high blood pressure and want to lower it.

References:

1. //www.ehow.com/about_5415684_natural-vitamins-high-blood-pressure.html
2. //www.ehow.com/about_5208471_vitamins-high-blood-pressure.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2919)

Date: December 08, 2013 10:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How vitamins help lower blood pressure naturally

Blood Pressure as Described

Blood pressure can be described as the force of blood as it goes through or Pumps in your blood vessels while circulating throughout your body. Those who have narrow arteries normally have a higher blood pressure, because the blood needs to be pumped much harder through their smaller passage-ways. Generally, high blood-pressure is usually caused by too much exercise or stress, but there are some people who may have chronic high blood-pressure. High blood-pressure symptoms can include; headaches, dizziness, and sometimes even nosebleeds. There are situations when there are no any symptoms and you won't know you've any problem until you get a stroke or have a heart attack, and this is why it's important for you to get your blood pressure checked regularly.

Below are some vitamins one can use to naturally lower their blood pressure:

Vitamin A

Vitamin A is a fat soluble which works primarily in body fat tissues. It prevents the LDL cholesterol and also prevents the build up of any plaque on your body's arteries. It can at times be quite toxic if you take too much of it, the recommended amount is only up to 5,000-IUs a day.

Vitamin C

Vitamin C will help in lowering and controlling your body's blood pressure in many ways. It will reduce the generation of all free radicals which can damage the artery walls. It will also help in fixing any damaged blood arteries, and will help elevate the levels of the HDL-cholesterol. If you happen to suffer from high blood-pressure, you should take a minimum of about 2,500-milligrams of vitamin-C every day. Vitamin C rich-foods can include; Oranges, red bell peppers, grape fruit,spinach, and tomatoes.

Vitamin E

Vitamin E will reduce the risk of suffering from heart disease and will also lower your blood pressure. Vitamin E will help protect your arteries from all effects of the LDL cholesterol. It's the most active anti-oxidant in the body. It's recommended you take up to 800 international units (IUs) of all natural vitamin E every day if you have a high blood pressure and want to lower it.

References:

1. //www.ehow.com/about_5415684_natural-vitamins-high-blood-pressure.html
2. //www.ehow.com/about_5208471_vitamins-high-blood-pressure.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2918)

Date: February 20, 2012 06:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How to manage high blood pressure with herbs and vitamins

What is high blood pressure?

High blood pressure, also called hypertension, is a very common health condition whereby one's blood is pumped through the arteries at a higher than normal pressure. High blood pressure may lead to serious health problems like heart disease and stroke.

The quantity of blood pumped by the heart and the level of resistance to the flow of blood in the arteries. The more one's heart Pumps blood and the narrower their arteries, the higher will be their blood pressure.

Many people have hypertension without even knowing it for years. This is because the condition does not usually show any symptoms. Having uncontrolled hypertension increases a person's risk of developing serious medical conditions, for example heart disease or stroke.

Typically, high blood pressure develops over a long period of time, usually for years and can affect almost everybody eventually. Thankfully, the condition can easily be detected. And once somebody knows they have it, they can get medical advice on how to control it from a doctor.

Causes of high blood pressure

There are two well known types of hypertension-primary/essential high blood pressure and secondary hypertension.

The first type of high blood pressure occurs in most adults and has no identifiable cause. It tends to develop slowly over a number of years. On the other hand, secondary hypertension is a condition that seems to appear suddenly and is usually caused by an underlying health condition. This type of blood pressure is higher in intensity compared to primary hypertension. Some medications and conditions can lead to secondary hypertension and they include:

Kidney disorders

Congenital blood vessel defects

Adrenal gland tumors

Certain medications, for example cold remedies, birth control pills, decongestants, pain relief tablets bought over the counter as well as prescription medicines Illegal drugs like amphetamines and cocaine

What are the symptoms of high blood pressure?

Most people who have hypertension do not have any signs or symptoms, no matter the seriousness of the condition.

Even though a small fraction of people with early-stage hypertension may get dizzy spells, dull headaches, or even heavy nose bleeding from time to time, these signs as well as symptoms normally do not appear until the condition has reached a critical and even life-threatening stage.

How high blood pressure can be controlled with vitamins and herbs Vitamins

Certain vitamins are said to lower high blood pressure as well as support one's cardiovascular system. One of the vitamins that can help is vitamin C. it is an important vitamin that can help to manage hypertension as it is rich in antioxidants, which help in prevention of stroke and heart attack. Other vitamins that can help to prevent or control high blood pressure include vitamins A, E, D and B6.

Whole grains, green leafy vegetables, fresh fruits, nuts, chicken, corn, salmon, just to mention a few, are good sources of essential vitamins that help in controlling hypertension.

Herbs

Herbs such as Hawthorn, Rauwolfia Serpentina/Indian snakeroot, and Ginkgo Biloba etc can also be used in lowering blood pressure. All these herbs can also strengthen your cardiovascular system to help in lowering the blood pressure and allow for better circulation. However, make sure you consult an experienced herbalist or healthcare specialist before you use any of the above herbs to control your hypertension.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2585)

Date: October 18, 2011 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Can I Raise Blood Pressure Naturally?

Overview

One of the leading causes linked to most illnesses in some form or the other is an imbalanced blood pressure. Statistics have shown that 1 out of 3 adults in the US have imbalanced blood pressure. So much of our bodily functions rely on normal blood pressure to work well. Let us put it this way, if your blood pressure is higher than it is supposed to be that means it is giving your body more workload than it is supposed to have, so in turn what will happened is, your body’s degeneration will be amplified. A lot of your systems will be overworked, your heart will be overworked and eventually depending on the cause your arteries will take a beating causing other organ failures in more severe cases. Now on the other hand if blood pressure is too low, you may feel fatigued all the time, light headedness, dizziness, nausea, close to fainting or anxiety and these are all things that we want to avoid.

Blood Pressure

This is the process in which the blood is carried from the heart towards other parts of your body. This is done through blood vessels called arteries and ultimately blood pressure is defined as the force of the blood in which it pushes the arterial walls. How much pressure is experienced is also directly proportional to how much the heart beats per minute in other words blood pressure is also directly proportional to the rate of your heart beat. The faster it beats the higher your blood pressure is. The blood pressure form of measurement is based on systolic over diastolic rates. Simply put the systolic rate is when the heart Pumps blood and the diastolic is when the heart is at rest in between Pumps or beats and that is why the diastolic is usually lower than the systolic rate. With that said by now you probably are able to make the conclusion that blood pressure will be at its highest when you are active, nervous, or excited and on the other hand it is at its lowest when you’re a sleep.

Why would you want to increase your blood pressure?

Most of us will probably think that, that idea is ludicrous since most of us would like to avoid high blood pressure and a lot of us are taking medications to support that effort and do things like exercising and all the other stuff to help fight against high blood pressure. However there is also a problem when blood pressure is too low as stated above and that is why some people need to increase blood pressure. There are a couple of ways to do it. First and foremost is for you to make sure you are hydrated well. High liquid volume in the body will promote higher blood pressure. Second is to lie down and elevate your feet. This will increase the return of blood to the heart therefore increasing blood pressure. Eat smaller meals so that the body will not divert so much blood to your digestive tract for digestion. Some studies also have shown that small amounts of caffeine daily may help increase low blood pressure.

You can also try herbs like bitter melon and yohimbe to elevate the heart rate. An elevated heart rate will effectively raise blood pressure. If you have low blood pressure or high, make sure you get tested every other day and record the results. Maintaining a BP level of 80/120 is optimal for good health.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2517)

Date: March 28, 2007 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Regulating Blood Pressure Naturally

--
Buy Supplements to lower Blood Pressure at Vitanet ®

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Date: July 13, 2005 09:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pain - Post Op and Relaxation

Relaxation, Music Reduce Post-Op Pain. New research has found that relaxation and music, separately or together, significantly reduce patients' pain following major abdominal surgery. The study, published in the May issue of the journal Pain, found that these methods reduce pain more than pain medication alone. Led by Marion Good, PhD, RN, of Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, the study is supported by the National Institute of Nursing Research (NINR), at the National Institutes of Health. "This is important news for the millions of Americans who undergo surgery and experience postoperative pain each year," said Dr. Patricia A. Grady, director of the NINR.

"Better pain management can reduce hospital stays and speed recovery, ultimately improving patients' quality of life." Dr. Good and her research team studied three groups of patients undergoing abdominal surgery. In addition to the usual pain medication, one group used a jaw relaxation technique, another group listened to music, and a third group received a combination of relaxation and music.

Findings revealed that, after surgery, the three treatment groups had significantly less pain than the control group, which received only pain medication. "Both medication and self-care methods which involve patient participation are needed for relief," said Dr. Good.

"These relaxation and music self-care methods provide more complete relief without the undesired side effects of some pain medications." The findings have important implications for the 23 million people who undergo surgery and experience postoperative pain annually in the United States. Pain can hamper recovery by heightening the body's response to the stress of surgery and increasing tissue breakdown, coagulation and fluid retention. Pain also interferes with appetite and sleep and can lead to complications that prolong hospitalization.

Dr. Good and her research staff worked with 500 patients aged 18-70, who were undergoing gynecological, gastrointestinal, exploratory or urinary surgery. Prior to surgery, those in the music, relaxation or combination groups practiced the techniques. The relaxation technique consisted of letting the lower jaw drop slightly, softening the lips, resting the tongue in the bottom of the mouth, and breathing slowly and rhythmically with a three-rhythm pattern of inhale, exhale and rest. Patients in the music group chose one of five kinds of soothing music--harp, piano, synthesizer, orchestral or slow jazz.

On the first and second days after surgery, all patients received morphine or Demerol for pain relief by pressing a button connected to their intravenous patient controlled analgesia Pumps. The groups receiving the additional intervention used earphones to listen to music and relaxation tapes during walking and rest, while the control group did not. The research team measured the patients' pain before and after 15 minutes of bed rest and four times during walking to see if the sensation and distress of pain changed.

Dr. Good found that during these two days postsurgery the three treatment groups had significantly less pain than the control group during both walking and rest. "Patients can take more control of their postoperative pain using these self-care methods," says Dr. Good. "Nurses and physicians preparing patients for surgery and caring for them afterwards should encourage patients to use relaxation and music to enhance the effectiveness of pain medication and hasten recovery."

Dr. Good's findings have implications for future research into the effectiveness of self-care methods on other types of pain, including chronic pain, cancer pain, and pain of the critically ill.

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Vitamin D Lack Linked to Hip Fracture. Vitamin D deficiency in post-menopausal women is associated with increased risk of hip fracture, according to investigators at Brigham and Women's Hospital in Boston, Mass. In a group of women with osteoporosis hospitalized for hip fracture, 50 percent were found to have a previously undetected vitamin D deficiency. In the control group, women who had not suffered a hip fracture but who were hospitalized for an elective hip replacement, only a very small percentage had vitamin D deficiency, although one-fourth of those women also had osteoporosis. These findings were reported in the April 28, 1999, issue of the Journal of the American Medical Association.

The study, conducted by Meryl S. LeBoff, MD; Lynn Kohlmeier, MD; Shelley Hurwitz, PhD; Jennifer Franklin, BA; John Wright, MD; and Julie Glowacki, PhD; of the Endocrine Hypertension Division, Department of Internal Medicine, and Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, was supported by grants from the National Institute on Aging (NIA) and the National Center for Research Resources (NCRR. These investigators studied women admitted to either Brigham and Women's Hospital or the New England Baptist Hospital, both in Boston, between January 1995 and June 1998.

A group of 98 postmenopausal women who normally reside in their own homes were chosen for the study. Women with bone deterioration from other causes were excluded from the study.

There were 30 women with hip fractures caused by osteoporosis and 68 hospitalized for elective joint replacement. Of these 68, 17 women also had osteoporosis as determined by the World Health Organization bone density criteria. All the participants answered questions regarding their lifestyle, reproductive history, calcium in their diet, and physical activity.

Bone mineral density of the spine, hip, and total body were measured by dual X-ray absorptiometry (DXA) technique, as was body composition. Blood chemistry and urinary calcium levels were analyzed. The two groups of women with osteoporosis did not differ significantly in either time since menopause or bone density in the spine or hip. They did, however, differ in total bone density.

The women admitted for a hip fracture had fewer hours of exercise than the control group. Fifty percent of the women with hip fractures were deficient in vitamin D, 36.7 percent had elevated parathyroid hormone (PTH) levels (a hormone which can stimulate loss of calcium from bone), and 81.8 percent had calcium in their urine, suggesting inappropriate calcium loss. Blood levels of calcium were lower in the women with hip fractures than in either elective group.

These researchers propose that vitamin D supplementation at the time of fracture may speed up recovery and reduce risk of fracture in the future. Current Dietary Reference Intake Guidelines contain a daily recommendation of 400 IU of vitamin D for people aged 51 through 70 and 600 IU for those over age 70.

"We know that a calcium-rich diet and regular weight-bearing exercise can help prevent osteoporosis. This new research suggests that an adequate intake of vitamin D, which the body uses to help absorb calcium, may help women to reduce their risk of hip fracture, even when osteoporosis is present," observed Dr. Evan C. Hadley, NIA Associate Director for geriatrics research.

"Osteoporosis leads to more than 300,000 hip fractures each year, causing pain, frequent disability, and costly hospitalizations or long-term care. "Prevention of such fractures would greatly improve the quality of life for many older women and men, as well as significantly reduce medical costs." The bones in the body often undergo rebuilding. Some cells, osteoclasts, dissolve older parts of the bones. Then, bone-building cells known as osteoblasts create new bone using calcium and phosphorus.

As people age, if osteoporosis develops, more bone is dissolved than is rebuilt, and the bones weaken and become prone to fracture. Also in many older persons, levels of vitamin D in the blood are low because they eat less or spend less time in the sun, which stimulates the body's own production of vitamin D.

Experts do not understand fully the causes of osteoporosis. However, they do know that lack of estrogen which accompanies menopause, diets low in calcium, and lack of exercise contribute to the problem. Eighty percent of older Americans who face the possibility of pain and debilitation from an osteoporosis-related fracture are women. One out of every two women and one in eight men over the age of 50 will have such a fracture sometime in the future. These fractures usually occur in the hip, wrist, and spine.

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Sleep Apnea, Diabetes Link Found. Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes and more likely to suffer a stroke in the future, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published today in the Journal of Oral and Maxillofacial Surgery. Sleep apnea, a serious condition marked by loud snoring, irregular breathing and interrupted oxygen intake, affects an estimated nine million Americans. The culprit? Carrying too many extra pounds.

"The blame falls squarely on excess weight gain," said Dr. Arthur H. Friedlander, associate professor of oral and maxillofacial surgery at the UCLA School of Dentistry and associate chief of staff at the Veterans Affairs Medical Center in Los Angeles. Surplus weight interferes with insulin's ability to propel sugars from digested food across the cell membrane, robbing the cells of needed carbohydrates. Diabetes results when glucose builds up in the bloodstream and can't be utilized by the body. Being overweight can also lead to obstructive sleep apnea, according to Friedlander.

"When people gain too much weight, fatty deposits build up along the throat and line the breathing passages," he explained. "The muscles in this region slacken during sleep, forcing the airway to narrow and often close altogether." Reclining on one's back magnifies the situation. "When an overweight person lies down and goes to sleep," Friedlander said, "gravity shoves the fat in the neck backwards. This blocks the airway and can bring breathing to a halt."

Friedlander tested the blood sugar of 54 randomly selected male veterans whom doctors had previously diagnosed with obstructive sleep apnea. He discovered that 17 of the 54 patients, or 31 percent, unknowingly suffered from adult-onset diabetes. Using the same sample, Friedlander also took panoramic X-rays of the men's necks and jaws. The X-rays indicated that 12 of the 54 patients, or 22 percent, revealed calcified plaques in the carotid artery leading to the brain.

These plaques block blood flow, significantly increasing patients' risk for stroke. Seven of the 12, or 58 percent, were also diagnosed with diabetes. In dramatic comparison, the 17 patients diagnosed with diabetes showed nearly twice the incidence of blockage. Seven of the 17 men, or 41 percent, had carotid plaques. Only five of the 54 patients who displayed plaques did not have also diabetes. If he conducted this study today, Friedlander notes, he would likely find a higher number of diabetic patients. After he completed the study in 1997, the American Diabetes Association lowered its definition for diabetes from 140 to 126 milligrams of sugar per deciliter of blood.

"This is the first time that science has uncovered a link between sleep apnea and diabetes," said Friedlander. "The data suggest that someone afflicted with both diabetes and sleep apnea is more likely to suffer a stroke in the future." "Persons going to the doctor for a sleep-apnea exam should request that their blood be screened for diabetes, especially if they are overweight," he cautioned. More than half of the individuals who develop diabetes as adults will need to modify their diet and take daily insulin in order to control the disease, he added.

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Stress, Surgery May Increase CA Tumors. Stress and surgery may increase the growth of cancerous tumors by suppressing natural killer cell activity, says a Johns Hopkins researcher.

Malignancies and viral infections are in part controlled by the immune system's natural killer (NK) cells, a sub-population of white blood cells that seek out and kill certain tumor and virally infected cells. In a study using animal models, natural killer cell activity was suppressed by physical stress or surgery, resulting in a significant increase in tumor development.

These findings suggest that protective measures should be considered to prevent metastasis for patients undergoing surgery to remove a cancerous tumor, according to Gayle Page, D.N.Sc., R.N., associate professor and Independence Foundation chair at the Johns Hopkins School of Nursing. "Human studies have already found a connection between the level of NK activity and susceptibility to several different types of cancer," says Page, an author of the study.

"We sought to determine the importance of stress-induced suppression of NK activity and thus learn the effects of stress and surgery on tumor development. "Many patients undergo surgery to remove cancerous tumors that have the potential to spread. If our findings in rats can be generalized to such clinical settings, then these circumstances could increase tumor growth during or shortly after surgery." The research was conducted at Ohio State University College of Nursing and the Department of Psychology at UCLA, where Page held previous positions, and at Tel Aviv University.

Results of the study are published in the March issue of the International Journal of Cancer. In laboratory studies, Page and her colleagues subjected rats to either abdominal surgery or physical stress, and then inoculated them with cancer cells. In the rats that had undergone surgery, the researchers observed a 200 to 500 percent increase in the incidence of lung tumor cells, an early indicator of metastasis, compared with rats that had not received surgery.

The experiment also showed that stress increased lung tumor incidence and significantly increased the mortality in the animals inoculated with cancer cells. "Our results show that, under specific circumstances, resistance to tumor development is compromised by physical stress and surgical intervention," says Page.

"Because surgical procedures are life-saving and cannot be withheld, protective measures should be considered that will prevent suppression of the natural killer cell activity and additional tumor development. "Researchers do not yet know how to prevent surgery-induced immune suppression, but early animal studies have shown increased use of analgesia reduces the risk."

The study was funded by the National Institutes of Health, and the Chief Scientist of the Israeli Ministry of Health. Lead author was Shamgar Ben-Eliyahu, Ph.D., and other authors were Raz Yirmiya, Ph.D., and Guy Shakhar.

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Date: June 25, 2005 10:21 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GARLIC IS A POWERFUL DETOXIFIER

GARLIC IS A POWERFUL DETOXIFIER

One of the most difficult toxins to neutralize in the body is heavy metal poisoning. Lead, mercury, cadmium, arsenic and copper pollutants threaten our health on a daily basis. Industrial pollution Pumps out enormous quantities of lead and mercury, not to mention the contribution of certain paints and amalgam fillings. Fish are frequently contaminated and copper can enter our bodies form metal water pipes commonly installed in our homes and work places. Treating heavy metal poisoning has involved a process called chelation. Japanese research has discovered, however, that raw garlic extract can effectively protect the body from metal tox i c i t y. Controlled studies performed on both animal and humans concluded that arlic can prevent the toxic effect of heavy metals from damaging and destroying erythrocyte membrane (certain type of blood cell).

“In another study, conducted in Russia, a drug made from Garlic extract was given to workers in industrial plants who were suffering from chronic lead poisoning. The daily doses of Garlic improved the symptoms of chronic lead poisoning and lowered the high porphyrin levels in the urine. The preparation also normalized elevated blood pressure in the majority of workers.”46

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=441)

Date: June 13, 2005 09:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Garlic for the Ages - eat garlic because it's good for your heart...

Garlic for the Ages by Phyllis D. Light, RH Energy Times, January 1 , 2004

If you eat garlic because it's good for your heart, you swallow a plant renowned through human history: Garlic was eaten by Roman soldiers for courage; Egyptian slaves ate it to build strength; Christians, Moslems and Hindus include it in their sacred books. Others have used it as an aphrodisiac, a vampire deterrent and a magical charm.

Garlic has a long history as a culinary and medicinal herb that people either love or hate. Its pungent aroma and warming flavor captivates or repels, but its wealth of natural chemicals does great things for your heart.

Garlic (Allium sativum), a member of the onion family, is native to Siberia but, in modern times, has become a treasured naturalized citizen grown all over the world. Garlic's use in folk medicine dates back about 7,000 years, making it one of the oldest known medicinal foods or herbs.

In modern times, garlic is generally used as a condiment lending a unique, pungent flavor to dishes, but in medieval times, garlic was cooked and eaten as a vegetable in its own right. Today you can revel in a wealth of garlic choices, consuming garlic raw, cooked in various recipes, as a dried concentrated powder, as a fresh liquid extract or as aged garlic powder.

Powerhouse Herb

Each little clove of garlic is a powerhouse of good-for-you natural compounds, vitamins and minerals. The biologically active constituents of garlic include allyl sulfur compounds as well as the minerals germanium and selenium.

When you chop up raw garlic and allowed it to stand for about 10 minutes or more, the herb's fragments release an enzyme that converts its compounds from allyl sulfur to another natural chemical called allicin.

Although some allicin is found in garlic before it is cut apart, the yield multiplies considerably when the garlic clove is chopped or pressed and exposed to water (Garlic Conference, Newport Beach, 11/15/98; Penn State).

Many researchers believe that the more allicin produced, the better the health benefits. (Although this is still being debated among the garlic cognoscenti.)

But garlic's benefits don't end meekly on the kitchen counter with its allicin content rising.

Cooked garlic and aged garlic contain other helpful chemicals called diallyl sulphides. Consequently, in any form, garlic produces beneficial health effects.

Fortunately, since raw garlic juice or oil can often irritate the stomach lining, especially in people with sensitive stomachs and delicate digestive systems, garlic supplements and cooked garlic are both helpful for heart health.

Aged Garlic Extract

Aging garlic significantly reduces its irritating compounds and makes it easier on the stomach.

In the aged form, all of garlic's healthy sulfur-containing compounds are converted to water- soluble compounds that retain garlic's natural health benefits. In addition, the pungent odor of the garlic is greatly reduced, an outcome many people desire.

When a group of researchers at Brown University studied the effects of aged garlic extract on people's cholesterol levels, they found that after six months, cholesterol dropped about 6% (Am J Clin Nutr 1996; 64:866-70).

In another study from Brown, researchers found that aged garlic extract reduced platelet adhesion, a sticky blood problem that can cause vessel blockages (New Drug Clin 45(3):456-66). When platelets are less sticky, they are less likely to form blood clots that can cause heart attacks.

Garlic and Heart Disease

A growing body of research shows that a clove of garlic a day can significantly reduce your risk of heart disease.

A four-year study of 280 people who took dried garlic powder three times a day found a striking reduction in the types of arterial plaque blockages that threaten the blood supply to your heart. Interestingly, in this particular study, women displayed a greater reduction in plaque than men (Atherosclerosis 2000; 150:437-8).

Another study found that garlic may also keep important blood vessels more supple and less likely to spasm. Arterial spasms have been linked to heart attacks and other cardiovascular problems in women.

Aortic Complications

As you age, the aorta, one of the main arteries that carries blood, may harden, reducing blood flow from the heart and placing damaging stress on a number of other bodily organs. In research at Ohio State University, people who took garlic supplements had 15% less aortic stiffness than people who avoided garlic (Circulation).

In this study, scientists found that the older people enjoyed the greatest cardiovascular benefits from daily garlic use.

Researchers believe this extra benefit is linked to the fact that as you age, the endothelial tissue in the linings of the aorta and other blood vessels become less responsive to the need to dilate (expand). As a result, when more blood flow is required, and the heart Pumps faster, these vessels take more of a beating from the friction of blood passing through them.

That restriction in dilation has two damaging consequences: In one instance, vessel walls can be injured. In response to these injuries, cholesterol collects on artery walls, plaque forms and the blood supply to the heart muscle can be restricted, leading to a heart attack. In other cases, arteries can restrict blood flow to the heart simply because of the inability to expand sufficiently.

The Ohio State researchers found that arteries in folks aged 70 to 80 benefited the most from taking garlic. But those in their 60s also benefited significantly.

Garlic's natural antioxidant properties can also help protect the heart from damage after surgery (BMC Pharmacology 9/02).

In a study performed on lab animals, researchers found that oxidative stress, a source of cell damage that takes place after surgery, dropped when the animals ate a diet that included garlic.

Oxidative stress can seriously reduce cardiac function, limit the amount of blood the heart can pump and cause permanent damage to the heart muscle.

Garlic Against Blood Clots

Under normal circumstances, blood clots serve a useful purpose: Cut yourself and a blood clot stops the bleeding. Without this clotting ability, you might bleed to death. But if your blood is too prone to clotting, these clumps can cut off blood supply to your heart and other organs, endangering your life.

In a study of apparently healthy individuals whose relatives had already suffered from heart disease, researchers found that their blood formed thick, tangled blood clots, increasing their risk of heart problems (Circulation rapid access 9/23/02). These blood clots are made of a substance called fibrin, a protein in the plasma that can form elastic threads that cut off blood flow.

While these researchers recommended aspirin as an anti-clotting measure for people at risk of heart disease, garlic can also help break up fibrin and possibly lower your chance of heart problems (Pharmatherapy 5(2): 83).

The fibrin that forms clots is produced by blood cells called platelets. Other scientists who have looked into garlic's benefits believe that one of its natural chemicals called ajoene may keep platelets from producing excessive fibrin and gumming up the flow of blood through arteries.

If you've rarely indulged in garlic, you may need a period of adjustment in growing accustomed to its unique taste and aroma. But its heart benefits confirm the long-ago observation by Pliny, an ancient Roman naturalist, that "garlic has powerful properties."

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Vitanet ®

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Date: June 02, 2005 12:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Higher Mind - Smart Nutrients for the Performance of a Lifetime...

Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life.

To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood.

Brain Cells – Issued at Birth

Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity.

Brain Cell Membranes

The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion Pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain.

Phosphatidyl Serine – Key to Cognition

For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4

The Chemistry of Thought

Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn.

Total Nutrition for the Brain

The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain.

The Importance of Magnesium

Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral.

B is for Brain Vitamins

HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters.

Brain Power

Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings.

For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.

References
1. Palmieri, G., et al. (1987). Clin. Trials J. 24: 73- 83.
2. Crook, T.H., et al. (1991). Neurol. 41: 644-49.
3. Nunzi, M.G., et al. In Phospholipids: Biochemical, Pharmaceutical and Analytical Considerations (ed. I. Hanin and G. Pepeu).
New York: Plenum Press, 1990.
4. Heiss, W.D., et al. (1993). Annals N.Y. Acad. Sci. 695: 327-31.
5. Passeri, M., et al. (1990). Int. J. Clin. Pharm. Res. X(1/2): 75-79.
6. Kohjimoto, Y., et al. (1988). Japanese Journal of Pharmacology 48(3): 365-71.
7. Philpott, William H. Brain Allergies: the Psychonutrient Connection. New Canaan: Keats, 1987.
8. Passariello, N., et al. (1983). Int. J. Clin. Pharmacol. Ther. Toxicol. 21: 252-56.

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VitaNet ®
VitaNet ® Staff

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=156)

Date: June 02, 2005 12:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

Heart Science 30 tabs

Your heart is crucial to every function of your body. It is the sole organ which Pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
1) generating energy,
2) decreasing harmful homocysteine levels,
3) fighting oxidized cholesterol,
4) maintaining the heart’s electrical rhythm, and
5) protecting artery and capillary linings.

Energy Generators for An Energetic Organ

Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

Homocysteine Regulators

B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

The Dangers of Oxidized LDL Cholesterol

While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

Cholesterol Fighters

Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

• Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells.

Artery Lining Protectors

Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

Capillary Strengtheners

Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

Heart Smarts

The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

Source Naturals HEART SCIENCE™

The Five Tiered Approach to Heart Health
Six tablets contain:
Vitamins and Minerals %USRDA
Pro-Vit A (Beta Carotene) 45,000 IU 900%
Vit B1 (Thiamine) 50 mg 3333%
Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
Vit B6 (Pyridoxine HCl) 25 mg 1250%
Coenzyme B6 (Pyridoxal-5-Phosphate)
25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
Vit B12 (Cyanocobalamin) 500 mcg 8333%
Folic Acid 800 mcg 200%
Vit C (Magnesium Ascorbate) 1500 mg 2500%
Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
Copper (Sebacate) 750 mcg 37.5%
Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
Potassium (Citrate) 99 mg *
Selenium (L-Selenomethionine) 200 mcg *
Silicon (From 400 mg of Horsetail Extract) 13mg *
* U.S. RDA not established.
Other Ingredients and Herbs
Coenzyme Q10 (Ubiquinone) 60 mg
L-Carnitine (L-Tartrate) 500 mg
Hawthorn Berry Extract 400 mg
Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
L-Proline 500 mg
L-Lysine (HCl) 500 mg
NAG™ (N-Acetyl Glucosamine) 500 mg
Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
Taurine (Magnesium Taurinate) 500 mg
Horsetail Extract (Yielding 31 mg of Silica) 400 mg
Inositol (Hexanicotinate) 50 mg

Reference:
1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.

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VitaNet ® Staff

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COENZYME Q10 - Transforming food into energy

Date: June 01, 2005 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: COENZYME Q10 - Transforming food into energy

Coenzyme Q10

It’s 3:30 p.m. and you feel irritable; you can’t seem to concentrate. You were so busy you skipped lunch. At last you bite into the sandwich that you were ready for 3 hours ago. By the time you have eaten half of it, energy is starting to flow through you. What happened? The answer to that question is both extremely complex and very simple. In essence, your body transformed the food into useable energy. CoQ10 is a crucial component of the primary energy generating cycle that takes place in each of the trillions of cells in our bodies. CoQ10 is essential for human life.

To transform that lunchtime sandwich into useable energy your body essentially has to burn it - just the way a car burns gasoline to drive its engine. This energy generating process takes place in structures called mitochondria - tiny power plants which are within every cell. Inside these energy generating stations, fats, sugars, and amino acids are transformed into ATP, an energy-rich molecule sometimes called the “energy currency” of the body.

Energy Generation Requires Nutrients

The body requires many nutrients in order to perform the complex biochemical processes that convert food into ATP “energy currency.” Some of these nutrients such as the B-vitamins are familiar to us. However, there are many other substances which are essential to this process. Coenzyme Q10 is one of these.

Functions of CoQ10

Several complex metabolic pathways are required in order for the body to transform that lunchtime sandwich into energy that you can feel and use. First glycolysis and the Krebs’ cycle break down large molecules of protein, carbohydrate and fat into smaller components. CoQ10 is a key enzyme in the Electron Transport Chain - the final stage in this extraordinary design. This pathway generates 90% of the ATP needed by the body from the food we eat. ATP provides the “energy currency” for the following crucial metabolic functions: 1) synthesis of cellular components including cholesterol and proteins (formed primarily by the liver), 2) nerve conduction (in the brain and peripheral nerves), and 3) energy for muscular contraction (of the heart and skeletal muscles). The Heart: The heart muscle (myocardium) consumes a tremendous amount of energy. Your heart beats over 100,000 times and Pumps 1,000 gallons of blood each day! CoQ10 is necessary for the generation of the energy required by the heart. Numerous scientific studies have demonstrated that supplementation with this nutrient may support normal heart function. Its presence is necessary for cardiac performance during exercise as exemplified by criteria including: blood flow, oxygen utilization, contractility and exercise tolerance. In addition, CoQ10 may play a role in the regulation of blood pressure. The Gums: Since the 1970’s scientists have been researching the effects of CoQ10 on the health of the oral tissues. Although the mechanism of action is not known, research has established that CoQ10 has a profound ability to preserve and maintain the health of the gums. Antioxidant Properties: CoQ10 plays an additional vital role in our metabolism as a protector of lipids in cell membranes. Laboratory studies have also shown that CoQ10 is more efficient than vitamin E, beta carotene or lycopene in safeguarding LDL cholesterol from oxidation by peroxides. This process is important for maintaining the health of our blood vessels.

Energy Insurance

CoQ10 is needed in body tissues where energy production is critical, such as the liver, brain and muscles. Therefore we include CoQ10 in significant potencies in many of our premium formulas, such as Life Force Multiple™, Élan Vitàl™, Heart Science™, Liver Guard™, MenoBalance™, Higher Mind™, MegaMind™ and Wellness Multiple™. We also offer a combination of CoQ10 and Lipoic Acid (30 mg each), CoQ10 Sublingual (30 mg and 60 mg), 30 mg CoQ10 Softgels with Bioperine® and 30 mg CoQ10 NutraSpray™. Our single CoQ10 products are CoQ10 in 15 mg, 30 mg, 75 mg, 100 mg, and Ultra Potency 125 mg caps.

References
1) Folkers et al., BCACQ, Elsevier, 1977
2) Judy et al., BCACQ, Elsevier, 1984.
3) Kamikawa, T. et al., American Journal of Cardiology, Vol. 56, August 1, 1985, p. 247-250.
4) Nohara et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1984.
5) Packer, L., Oxidative Stress and Aging, Birkhauser Verlad, 1995.
6) Stocker, et al., Proceedings of the National Academy of Sciences, Vol. 88, pp 1646-1650, March 1991.
7) Tortora, G. Principles of Human Anatomy, 4th Ed., Harper & Row, New York, 1986, p. 301.
8) Wilkinson and Arnold, Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.
9) Yamagami et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.

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