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  Messages 1-65 from 65 matching the search criteria.
What Cellular Mitochondria Does in the Body Darrell Miller 4/28/22
Argan Oil Benefits Darrell Miller 5/28/19
Give your healthy diet a boost with supplements - USA TODAY Darrell Miller 8/27/17
CoQ10 — A Nutritional Powerhouse for Mitochondrial Health Darrell Miller 12/27/16
What Are The Benefits Of Ubiquinol Vs Regular CoQ10? Darrell Miller 5/31/14
Boost Energy With CoQ10 And L-Carnitine Darrell Miller 11/21/13
CoQ10: What You Ought to Know about This Substance? Darrell Miller 3/26/13
What Causes High Blood Pressure And What Can Reduce And Prevent It? Darrell Miller 12/28/12
stroke, what is it? Darrell Miller 9/28/10
Natural Vitamins for the Heart Darrell Miller 7/6/10
Natural Remedies To Control Blood Sugar Darrell Miller 6/17/10
Antioxidants and your health Darrell Miller 5/17/10
Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it Darrell Miller 2/25/10
Herbs, Serrapeptase, and your Sinus Darrell Miller 2/18/10
Omega Red And Cholesterol Darrell Miller 8/28/09
Thrombophlebitis Darrell Miller 4/15/09
Vitamins and Herbs Darrell Miller 4/3/09
Phytoestrogen Darrell Miller 3/27/09
Psyllium Husk Fiber Darrell Miller 3/18/09
Migraines Darrell Miller 2/21/09
Hay Fever Darrell Miller 2/19/09
Ubiquinol Reduced CoQ10 Darrell Miller 4/7/08
Alpha Lipoic Acid is a Powerful Antioxidant Darrell Miller 2/15/08
Seniors Need More Than a Multiple with Only 100 Percent of the RDA Darrell Miller 1/21/08
Give Your Health A Boost With Silica Hydride A Powerful Antioxidant Darrell Miller 1/18/08
Support Healthy Joint Function With Discount Vitamins Darrell Miller 11/22/07
Ubiquinol Darrell Miller 10/24/07
Active Coenzyme Q10 Darrell Miller 7/7/07
The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium Darrell Miller 5/18/07
CoQ10 for Heart Health Darrell Miller 3/28/07
Regulating Blood Pressure Naturally Darrell Miller 3/28/07
Neurological Health and CoQ10 Darrell Miller 2/25/07
For Better Heart Health ... Darrell Miller 2/6/07
Lower Cholesterol Naturally! Darrell Miller 10/6/06
What are you really Getting? Darrell Miller 8/21/06
HDL Booster - Boost your good cholesterol Darrell Miller 3/16/06
Ola Loa Multi-Vitamin Mineral Formula Darrell Miller 2/22/06
High Absorption CoQ10 Darrell Miller 2/13/06
Molecularly Distilled Omega-3 fish Oil Fact Sheet Darrell Miller 1/12/06
Your Cells Supercharge Your Cells Darrell Miller 12/20/05
GliSODin Anti-Aging and Antioxidant Protection Darrell Miller 12/19/05
Coenzyme Q10 and Cardiovascular Health. Darrell Miller 12/13/05
Tru-E Bio Complex Darrell Miller 12/8/05
Carnitine Creatinate Darrell Miller 12/8/05
Skin Eternal #1 Skin Care Line – Source Naturals Darrell Miller 11/4/05
CoQsol-CF™provides all the well-known benefits of CoQ10 Darrell Miller 7/26/05
LIFE FORCE MULTIPLE - Essential Nutrients to Support Your Low Carb Lifestyle.. Darrell Miller 6/29/05
Life Force - The Energy Activator Darrell Miller 6/29/05
SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol... Darrell Miller 6/29/05
SPECIFIC ACTIONS ASSOCIATED WITH GARLIC Darrell Miller 6/25/05
RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available Darrell Miller 6/24/05
CLA and Ather osclerosis Darrell Miller 6/22/05
Pep Up and Go! Darrell Miller 6/14/05
Energy Vitamins Darrell Miller 6/11/05
Re: Natural Energy Production ... Darrell Miller 6/9/05
Skin Eternal - Replenish Your Skin Darrell Miller 6/6/05
Red Yeast Rice For Lipid Wellness Darrell Miller 6/4/05
Menopause Multiple - Eternal Woman Darrell Miller 6/3/05
NutraSpray in Melatonin, Proanthodyn, and St. John's wort Darrell Miller 6/3/05
Joint Response and Ultra Joint Response Darrell Miller 6/2/05
Heart Science - A Five-Tiered Approach to Heart Health ... Darrell Miller 6/2/05
HEART RESPONSE - Comprehensive Support for a Healthy Heart! Darrell Miller 6/2/05
Gluco Sciense - Take Control of your Blood Sugar ... Darrell Miller 6/2/05
Fibro Response - Feel your Vitality ... Darrell Miller 6/2/05
Life Force Multiples -- Source Naturals Darrell Miller 5/21/05



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What Cellular Mitochondria Does in the Body
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Date: April 28, 2022 04:19 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What Cellular Mitochondria Does in the Body

If you want to stay healthy, it's important that you know what cellular mitochondria does in the body. Mitochondria are organelles found in the cytoplasm of cells. They are responsible for producing energy for the cell. Without them, the cell would not be able to function properly. We will discuss the role of mitochondria in the body, and how they impact our health.

What are mitochondria and what do they do in the body

Mitochondria are organelles that play an important role in the energy metabolism of cells. Most of the oxygen we breathe is used by mitochondria to convert glucose from the food we eat into ATP, the energy molecule used by our cells. Therefore, mitochondria are often referred to as the "powerhouses" of the cell. In addition to producing ATP, mitochondria also have other important functions, such as regulating cell growth and death, as well as calcium homeostasis. Mitochondria are unique in that they have their own DNA separate from the DNA in the cell nucleus. This mitochondrial DNA is passed down from mother to child, which is why defects in mitochondrial function can lead to diseases that are inherited in a maternal lineage. Although most of our cells contain only a single nucleus, they may contain hundreds or even thousands of mitochondria. This allows them to produce enough ATP to meet the energy needs of the cell.

How mitochondrial dysfunction can lead to health problems

Mitochondria are integral to many essential physiological processes in the body. Not only do they produce energy for cells, but they also play a key role in maintaining cellular structures and initiating cell division. Therefore, any disruption of normal mitochondrial function can have far-reaching consequences for overall health and well-being. Maladaptive responses to environmental stressors, such as chemical exposure or radiation, are among the most common causes of mitochondrial dysfunction. These stressors result in damage to mitochondrial DNA and can cause problems with cell division and abnormal growth patterns, which can lead to a range of disorders and chronic diseases. For example, mitochondrial dysfunction has been linked to conditions like Alzheimer's disease and type 2 diabetes, as well as cardiovascular disease and cancer. Therefore, it is important to understand the role that mitochondria play in maintaining healthy functioning bodies and take proactive steps to prevent or reverse damage from maladaptive responses to environmental stressors.

Mitochondria and Longevity

Mitochondria are specialized organelles found within our cells that perform many critical functions, including generating energy to support cellular processes and maintaining healthy cell function. These organelles are the site of many important chemical reactions, often referred to as oxidative phosphorylation or metabolism. Studies have shown that Proper functioning of these organelles is essential for healthy aging, and may be a key factor in determining how long we live. By promoting mitochondria health and making lifestyle changes that help to promote healthy mitochondria, we can take an important step towards optimizing our longevity potential. This includes eating a nutrient-rich diet with a focus on foods high in antioxidants, managing stress levels through regular exercise and relaxation techniques, and avoiding environmental toxins that can damage mitochondria health. Through such strategies, we can give ourselves the best chance at living a long, full life.

Ways to protect your mitochondria and keep them healthy with PQQ

PQQ, or pyrroloquinoline quinone, is an important molecule for the functioning of mitochondria in the human body. This compound plays a crucial role in adenosine triphosphate (ATP) synthesis, the fundamental energy currency of biological systems. By driving cellular processes that release energy for metabolic use, PQQ plays a key role in maintaining mitochondrial health and efficiency. Additionally, PQQ has been shown to exhibit powerful antioxidant properties, which help to mitigate the effects of oxidative stress on mitochondria and other critical cells in the body. Overall, PQQ is an essential component of healthy mitochondrial function and a crucial nutrient for energy production and overall metabolic health.

D-ribose, the Mitochondria, and Energy

D-ribose is a naturally occurring sugar that plays an important role in cellular metabolism and energy production. This nutrient is especially important for cells that rely on a lot of energy, such as those found in the heart and muscles. D-ribose helps these cells to generate adenosine triphosphate, or ATP, which is the main energy currency used by cells to drive chemical reactions. Additionally, research has suggested that d-ribose can help to improve physical endurance and reduce the pain and stiffness associated with exercise, making it an important part of a healthy, active lifestyle.

Also, D-ribose is a simple sugar that plays an important role in the structure and function of mitochondria, the powerhouses of the cell. In addition to supplying energy to the cells, mitochondria also help to regulate cell growth and death. D-ribose is essential for the proper function of mitochondria, and it plays a key role in energy production. Studies have shown that D-ribose can help to improve mitochondrial function and reduce fatigue. In addition, D-ribose supplements have been shown to improve exercise performance and increase energy levels. These effects are likely due to the ability of D-ribose to help the body produce more ATP, the energy currency of the cell. For these reasons, D-ribose is an important nutrient for maintaining healthy mitochondria and supporting cellular energy production.

Another important nutrient for the mitochondria is CoQ10

The process of producing energy is called oxidative phosphorylation, and it involves the transfer of electrons from nutrients to oxygen. This reaction creates a proton gradient across the mitochondrial membrane, which is used to generate ATP, the energy currency of the cell. Coenzyme Q10 (CoQ10) is an important component of this process. It acts as an electron carrier, shuttling electrons between enzymes in the respiratory chain. It also helps to maintain the proton gradient, allowing the mitochondria to continue generating ATP. Without CoQ10, oxidative phosphorylation would grind to a halt, and cells would quickly run out of energy. Consequently, CoQ10 plays a vital role in energy production and cellular metabolism.

The bottom line is that both D-ribose and CoQ10 are important nutrients the body needs to maintain optimal energy levels. If you’re feeling run down, low on energy, or just generally not your best, consider taking a supplement containing these two nutrients. You may be surprised at how much better you feel once you start including them in your diet. What’s stopping you from giving them a try?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6395)


Argan Oil Benefits
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Date: May 28, 2019 11:07 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Argan Oil Benefits





Moroccans have been using argan oil for centuries because it has a good, nufty flavor but also many health benefits. This has made the oil, derived from the fruit of the argan tree, very popular worldwide although it is native to Morocco. It is widely known and used for culinary, cosmetic, and medicinal purposes. The author suggests some 12 uses of argan oil in the blog. One of the uses is that it contains essential nutrients which are usually fatty acids like oleic and linoleic acid. These fatty acids are good sources for the health and also it contains a rich source of vitamin E. Another usefulness of argan oil is that is has antioxidant and anti-inflammatory properties. Some of its compounds that make this possible are vitamin E, CoQ10, melatonin, and plant sterols. The author states that more research is needed though to fully understand how argan oil is antioxidant and anti-inflammatory. Another good reason to use argan oil is that it boosts heart health. This is due to the omega-9 fatty acid, oleic acid, it contains. Other reasons to use argan oil are found in the blog.

Key Takeaways:

  • Argan oil has been used in Moroccan cooking for centuries because of its flavor and health benefits.
  • Argan oil is a healthy fat that is good for the hair, skin, and eyes.
  • Because argan oil is high in anti-oxidants, it has promising benefits for heart health and diabetes.

"Although native to Morocco, argan oil is now used across the globe for a variety of culinary, cosmetic and medicinal applications."

Read more: https://www.ecowatch.com/argan-oil-2634443123.html

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Give your healthy diet a boost with supplements - USA TODAY
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Date: August 27, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Give your healthy diet a boost with supplements - USA TODAY





There are many supplements out there. You have to research them so you can get good ones because they aren't all created equal, but there are reasons why taking them is helpful. They help you get the nutrients you need in case your diet is lacking. They can also help you if you are low on something because of a health condition. A good balance of nutrients will help your body to perform at its very best.

Key Takeaways:

  • Older women's bodies do not absorb nutrients as efficiently as they age.
  • Some supplements including calcium vitamin D, Magnesium, Omega 3 Fatty acids, Vitamin B-12, Resveratrol, turmeric, grapeseed oil, coenzyme Q10, and general multivitamins may benefit older women.
  • It is advisable to check with one's doctor before beginning a new supplement.

"It seems as if there isn’t anything that Curcuma longa can’t do."

Read more: https://www.usatoday.com/story/news/nation/2017/08/18/give-your-healthy-diet-boost-supplements/579373001/

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CoQ10 — A Nutritional Powerhouse for Mitochondrial Health
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Date: December 27, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CoQ10 — A Nutritional Powerhouse for Mitochondrial Health





coenzyme Q10, which is referred to as CoQ10 is gaining popularity in the supplement marketplace. The number of Americans who are using this supplement has risen to twenty-four million people. This is good news as research shows its benefits. New research shows it keeps the mitochondria healthy, allowing for oxygen to be converted to energy.

Key Takeaways:

  • At present, at least 1 in 4 American adults over the age of 40 are taking a statin — ostensibly to protect their heart health.
  • This is the enzyme inhibited by statin drugs. This means that, in addition to lowering your cholesterol, the drug also compromises your body's ability to benefit from a healthy and cleaner-burning fuel (fat).
  • Recent research found that taking CoQ10 in combination with selenium improves heart function and cuts cardiovascular mortality by nearly 50 percent in elderly people.

"Between 2000 and 2016, the number of Americans using CoQ10 increased from an estimated 2 million to 24 million, and the number of brands featuring CoQ10 has increased from 18 brands to 125."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.prohealth.com/library/showarticle.cfm%3Flibid%3D29771&ct=ga&cd=CAIyGjVkYjY3ZDViNDdiNGM3ZTc6Y29tOmVuOlVT&usg=AFQjCNFStHXdUv1oYIMpcXavYYI0sc130w

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What Are The Benefits Of Ubiquinol Vs Regular CoQ10?
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Date: May 31, 2014 06:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Benefits Of Ubiquinol Vs Regular CoQ10?

fruits and vegetables Nutritional Supplement

In modern society, nutritional supplements have become a common method to improve health. A wide range of specific needs determines the use of different supplements, but there are a few that will work in just about everyone and improve their health.

What is a CoQ10

Coenzyme Q10, commonly abbreviated to CoQ10, is one of those universally effective supplements. This vitamin-like substance offers far-reaching benefits for the human body. It has a crucial role in the body's energy maintenance and it's an extremely powerful antioxidant. This substance is naturally produced by the body, but as we get older, the organism's ability to synthesize CoQ10 weakens progressively. It is, therefore, recommended that people initiate a regular intake of CoQ10 somewhere at the adult or even young adult life stage. This is a commonly prescribed supplement for old people owing to its longevity and energy inducing benefits, but it's especially critical for those who are medicated with statin drugs because these are known to reduce CoQ10 levels in the organism. Elite athletes can also benefit from this substance to achieve higher peak power levels.

CoQ10 supplement is available in two forms: fully oxidized (Ubiquinone) and fully reduced (Ubiquinol).

What is an Ubiquinol

Ubiquinol is the most efficient way to take advantage of this supplement because it's the fully reduced form of CoQ10 that our body actually absorbs and uses. The consumption of Ubiquinone requires our body to firstly metabolize and convert it into Ubiquinol. This process limits the speed and efficiency of CoQ10 absorption, requiring larger quantities to be consumed for similar health effects, not to mention that the metabolism has a tendency to worsen with age. Ubiquinone is more widely available and is cheaper, though.

It is usually recommended for people around the age of 35 - 40, to start taking Ubiquinol instead of Ubiquinone. This is when the efficiency of Ubiquinol eventually compensates its higher price tag over Ubiquinone. Turning the ingestion of CoQ10 supplement into a habit is one of the best ways to potentiate a long and healthy life.

Sources:

  1. en.wikipedia.org/wiki/Ubiquinol
  2. en.wikipedia.org/wiki/Coenzyme_Q10#Biosynthesis
  3. articles.mercola.com/sites/articles/archive/2013/11/03/coQ10-vs-ubiquinol.aspx
  4. www.bodybuilding.com/fun/coQ10-ubiquinone-ubiquinol-whats-the-difference.htm
  5. www.ncbi.nlm.nih.gov/pmc/articles/PMC3661336/

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Boost Energy With CoQ10 And L-Carnitine
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Date: November 21, 2013 08:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Energy With CoQ10 And L-Carnitine

CoQ10 and L-Carnatine

 L-CarnatineCoQ10 and L-Carnitine offer double protection for the heart and the brain in just a single tablet. You obtain all benefits for your heart at 100% from CoQ10, while L-Carnitine supports your memory, learning ability, and focus. The exclusive combination of CoenzymeQ10 and L-Carnitine encloses an absorbable, water soluble capsule of CoQ10 and L-Carnitine, which is important for proper usage.

Why are CoQ10 and L-Carnitine Supportive in Energy Boost?

CoQ10 Energy Boost

CoQ10 is a vital nutritional element found in all body cells, in particular the mitochondria, in which most energy is generated. The major function of this coenzyme is to assist in the process of oxygen and food conversion into energy. As people grow older their ability to naturally, to produce this coenzyme decays.

At the same time as Coenzyme Q10 is taking part in the production of energy in each cell of your body, it is considered be remarkably imperative for the high energy requirements of the heart. The heart needs vast energy amounts, because it is the hardest worker in your entire body. Coenzyme Q10 seems to be indispensable for this process. It offers you sufficient antioxidant provision, protecting the body cells from damage of the free radicals, and proffering a dynamic function of the immune system.

L-Carnitine Energy Boost

L-Carnitine transports indispensable fat acids into the same organ where CoQ10 plays its major function - the mitochondria. There, with the help of L-Carnitine, all fatty acids are turned into energy. However, the beneficial function of L-Carnitine does not end here. In addition, it also supports the transportation of toxins outside the body. You can think of the problems that might occur if these vital body processes are not fully operational. At the same time however, the major impact of L-Carnitine over the body is directed towards the brain:
  • Cognitive function and concentration support
  • Cell membrane health support
  • Improves clarity and happiness
Encouraging the overall health of your brain, while offering your heart supreme support, the combination of CoQ10 and L-Carnitine is the best solution for you, in terms of:
  • Supporting your heart's energy needs
  • Providing essential nutrition for all cells of the body
  • Delivering powerful antioxidants, which protect your body
References:
  1. //www.webmd.com/heart-disease/heart-failure/tc/coenzyme-Q10-topic-overview
  2. //www.webmd.com/vitamins-supplements/ingredientmono-1026-L-CARNITINE.aspx?activeIngredientId=1026&activeIngredientName=L-CARNITINE
  3. //www.poliquingroup.com/ArticlesMultimedia/Articles/Article/767/Top_12_Reasons_to_Use_Carnitine.aspx
  4. //nutritionalengineering.org/coQ10-acetyl-l-carnitine-supplement.htm
  5. //www.livestrong.com/article/489829-why-should-i-take-l-carnitine-with-coQ10/

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CoQ10: What You Ought to Know about This Substance?
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Date: March 26, 2013 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10: What You Ought to Know about This Substance?

Coenzyme Q10 or simply CoQ10 is a substance naturally present not only in a human's body but as well as with the other mammals. It plays a vital role in the production of energy. Back in the year 1957, Dr. Frederick Crane successfully used the mitochondria from the cells of a beef heart in order to locate Coenzyme Q10. But the truth of the matter is that, the substance is also present in human mitochondria. Basically, this substance has antioxidant properties which are highly beneficial in protecting the body against the free radicals present in the environment. Below are some relevant details you ought to know about this substance.

Here they are:

CoQ10 in Kreb's Cycle

There are a number of chemicals that the body needs to induce metabolism and one of those chemicals is CoQ10. The Kerb's Cycle is the body's mechanism to convert certain enzymes into energy. In order to achieve that, the body needs CoQ10 to facilitate the conversion of the enzymes in energy production. CoQ10 is fundamental in the Kerb's Cycle as it supports the electron transport chain in which the oxidative phosphorylation of the ADP (adenosine diphosphate) into ATP (andenosine triphosphate) needs electrons that are exactly delivered where they must be. Without CoQ10, the entire Kerb's Cycle process would certainly fail. The mitochondria of every power cells synthesize CoQ10 so the substance is present in almost all the body parts. However, the heart consumes the most CoQ10 for the reason that it has the most number of mitochondria and it keeps on working even while the body is at rest.

CoQ10 Deficiency

If the Kerb's Cycle fails due to CoQ10 deficiency, the person will feel exhausted and weak. But aside from that, there are other conditions that are often associated with the deficiency such as cardiovascular related diseases, Parkinson's disease and gum disease. Conversely, it doesn't necessarily mean that those diseases are brought about by CoQ10 deficiency.

CoQ10 Dietary Sources

The main sources of CoQ10 include fish oil, whole grains and organ meats. With a balance diet, people can get sufficient amount of coenzyme Q10.

CoQ10 Supplements

Aging is an inevitable process and it can affect the synthesis of CoQ10. As humans grow older, the production of the coenzyme Q10 gradually decreases. It was mentioned earlier some of the foods that are incredibly beneficial in maintaining ample amount of CoQ10 in the body. But people who do not really include those foods in their diet should not worry for there are now food supplements that contain CoQ10.  Some medications like cholesterol meds can prevent the body from using CoQ10, this is when it is essential for one to take a supplement.

Fortunately, with the advent of medical researches and innovative technology in drug manufacturing, CoQ10 can now be ingested into one single tablet, soft gel capsule, hard shell capsule or an oral spray. CoQ10 is a fat-soluble substance so taking it along with foods is highly encouraged.

Who Takes CoQ10 Supplement?

Children under 18 years old are not allowed to take CoQ10 supplements unless prescribed by the doctor. For adults at the age of 19 or older, the recommended dosage in 30 - 600 mg daily. Higher dosage may be taken for special conditions.

Humans need energy in order to carry out all the tasks. Therefore, CoQ10 must be taken daily, whether from foods or supplements, so the body has the energy to move.

Have you had your CoQ10 Today?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2834)


What Causes High Blood Pressure And What Can Reduce And Prevent It?
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Date: December 28, 2012 11:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Causes High Blood Pressure And What Can Reduce And Prevent It?

High blood pressure is one of the most common conditions people suffer from in first-world countries; throughout the last few decades civilized countries have becomes exponentially more reliant on technology, without forgetting the rise of the fast food industry. In conjunction with the sedentary lifestyles most people lead nowadays, this has led to an increase of people with cardiovascular health problems. According to the American Heart Association, around 33% of adults in the United States are suffering from hypertension.

The silent killer

The disease is not known as the silent killer for nothing, as a person can live with it for years and years without even experiencing any symptoms. However, as time goes by the disease starts to take its toll on the body, with symptoms including dizziness, headaches and nosebleeds. However, if gone unchecked for a long time the condition is going to worsen considerably, eventually leading to the development of serious cardiovascular problems, including coronary heart disease.

What precisely causes high blood pressure?

For starters, one's body fat percentage plays an important role; the more fat a person has, the more the walls of their arteries are clogged, the higher the blood pressure rises. A lack of physical activity has also been known to help the condition develop as it forces your heart to contract itself more often. Intake of products such as tobacco, alcohol, sodium and potassium can all lead to an increase in your blood pressure, as well as your risk of heart disease.

Stress is a factor which often gets overlooked, but the truth is that when you tense up, your heart starts pumping blood faster, which consequently increases the pressure in your arteries. Finally, there is the one factor which cannot be controlled: genetics. Indeed, if a person has a family history of hypertension, that person is likely to suffer from it as well.

While it is possible to treat high blood pressure with chemical over-the-counter pharmaceutical remedies, they often bring about a slew of side effects which can cause problems even worse than the ones experienced with the blood pressure.

Natural Remedies

Fortunately, there are a few natural remedies which can be used to fight the condition.

For starters, you can take magnesium supplements which are sold by numerous companies, generally in the form of capsules. Magnesium is the most common mineral needed by the body and it helps to regulate one's blood levels. If you don't feel like taking supplements, you could always eat foods rich in magnesium, which basically translates to consuming lots of green vegetables, nuts, seeds and unrefined grains. 

Hibiscus tea

Hibiscus tea is another apparent miracle of nature; drinking it on a regular basis will slowly decrease one's hypertension. A clinical study was actually conducted in order to determine the tea's effectiveness, and it was found that it can noticeably improve the condition of those suffering from mild or moderate hypertension.

Coenzyme Q10

Finally, you might want to look into the Coenzyme Q10, a natural supplement which has undergone clinical studies. More precisely, there was a twelve-week double-blind placebo-controlled study involving eighty-three subjects with hypertension. They were treated for the entire duration with 17.8 mm Hg of the Coenzyme Q10, and in the end their pressure was significantly reduced.

Needless to say, there are countless more natural remedies which can help deal with high blood pressure, with the best part being that most of them don't cost much and are readily available for purchase anywhere. In some cases, you can even do it at home by yourself. All in all, as long as there are natural methods to try it is highly recommended that you stay away from pharmaceutical treatments; not only will they burn a hole in your wallet, they may very well leave you worse for wear.

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stroke, what is it?
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Date: September 28, 2010 03:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: stroke, what is it?

A stroke occurs when a clot forms inside an artery that blocks the flow of blood to the brain. This is also called a thrombus. Embolism, which is a wandering clot, is carried in the bloodstream until it wedges in one of the arteries that lead to the brain. Aneurysms are blood-filled pouches that balloon out from weak spots in the artery wall and burst. A hemorrhage results when a defective artery in the brain that bursts, flooding the surrounding tissue with blood.

A mild attack can lead to temporary confusion and light-headedness, along with difficulty in speaking clearly, weakness on one side of the body, visual dimness and confusion, severe speech difficulties, and/or sudden or gradual loss or blurring of consciousness. Additionally, amnesia can occur, but it is not typically permanent. A coma can even result for short or long periods.

It is important to watch for early warnings of stroke. Although they may only last a few moments, early warnings include fainting, stumbling, numbness or paralysis of the fingers of one hand, blurring of vision, seeing bright lights, and loss of speech or memory. It is much wiser and significantly less expensive to start improving health in order to prevent this disease. Some doctors who have treated thousands of people suffering from stroke believe that most strokes can typically be prevented.

The Chinese often view strokes as being caused by blood stasis and stagnation of the liver. Chinese medical practitioners attempt to prevent strokes and treat them by treating constipation. Constipation causes a poisoned bloodstream, setting the stage for a possible stroke. Poisoned blood flows through thousands of miles of arteries, veins, and capillaries. The walls of the arteries are made up for cells, which are subject to the same injury from toxins as the cells in the kidneys. The kidneys degenerate at the same time that the arteries do and even from the same causes. When the walls thicken and harden, degeneration results. As they harden they become more brittle, causing them to burst more easily under pressure. Pressure increases as the hole through the arteries grows smaller. AS the walls become more brittle, the extra pressure causes the blood pressure to rupture. This, in turn, causes a stroke. The brain cells rely primarily on oxygen-rich blood in order to get nourishment. If they don’t receive this nourishment, the brain cells will die. Other causes of this are poor diet, lack of exercise, obesity, and smoking.

Emotional health is an essential part to any healing. Strokes are often associated with resistance to change, giving up on life, and getting tired of doing all the same things over and over. It is important that we learn to accept changes and are able to go with the flow of life. Life can be exciting. Changes provide us with a new perspective on living.

Some herbs and supplements have been used to help as a preventative. These include vitamin E, vitamin C, coenzyme Q10, garlic, evening primrose oil, lecithin, chlorophyll, flaxseed oil, and germanium. For additional information on any of these, please contact a representative from your local health food store.

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Natural Vitamins for the Heart
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Date: July 06, 2010 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamins for the Heart

It has been consistently revealed by epidemiological research that individuals with a high dietary intake of antioxidant vitamins have a risk that is lower-than-average of cardiovascular disease. This evidence seems to be especially consistent for vitamin E. Additionally, many clinical studies show that magnesium supplementation is of significant benefit in the treatment of cardiac arrhythmias and in reversing the depletion of potassium that comes along with a magnesium deficit. Many cardiovascular events like angina pectoris, congestive heart failure, and cardiomyopathy are related directly to low magnesium status. Coenzyme Q10 is an essential component in cellular energy production. This nutrient is also prevalent in the heart muscle. When tissue levels of CoQ10 are low, there is an association with several cardiovascular complications. Among these are angina, congestive heart failure, cardiomyopathy, hypertension, and mitral valve prolapse. Research has found that the trio of coenzyme Q10, vitamin E, and magnesium plays a crucial role in the maintenance of cardiac health and the prevention of disease states.

The cardio-protective effect of vitamin E seems to come from its ability to bind to LDL cholesterol, which protects it from free-radical induce oxidative damage along with the consequent buildup of atherogenic plaque. Low levels of vitamin E in the blood are a predictive factor of heart health almost 70% of the time.

Studies on the general population have suggested that there is a link between the intake of calcium and blood pressure. Although results of the studies have not been consistent, there are several studies showing that calcium supplementation can lower blood pressure in those individuals who experience hypertension. Overall, those intakes of calcium that are sub-optimal contribute directly to hypertension. It seems that dietary calcium reduces blood pressure by normalizing intracellular calcium levels.

Supplementation with magnesium is of benefit for the treatment of cardiac arrhythmias and the prevention of potassium depletion. Both magnesium and potassium play an important role in the functioning of the heart. Several studies have found that there is improvement in heart function in those patients that have cardiomyopathies when they supplement with magnesium. Since magnesium acts in so many ways to enhance cardiac function and optimize cellular metabolism, magnesium is widely recognized as a critical nutrient for general cardiac support.

Several double-blind studies have taken place in those patients that experience various cardiomyopathies in order to show the benefits of CoQ10 supplementation. One study reported an 89% improvement rate in 80 cardiomyopathy patients who were treated with CoQ10. The coenzyme also appears to moderate blood pressure through the usual mechanism, as it lowers cholesterol levels and also stabilizes the vascular system with its antioxidant properties. Because of this, it is able to reduce vascular resistance. Several studies on CoQ10 supplementation have confirmed that this nutrient posses the ability lower both systolic and diastolic pressures by up to ten percent.

There are other nutrients that play important roles in optimizing cardiovascular health and reducing hypertension. Among these nutrients are gamma tocopherol, calcium, magnesium, l-carnitine, acetyl-l-carnitine, procyanidolic oligomers, phenolic compounds, and lycopene. As you can see there are many natural supplements that can help the cardiovascular system. Remember to always consult your doctor before adding supplements to your diet while on prescription drugs. Look to your local or internet health food store for quality vitamins, herbs, and specialty formulas to boost your health and wellness.

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Natural Remedies To Control Blood Sugar
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Date: June 17, 2010 01:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Remedies To Control Blood Sugar

Diabetes has now been found to be the seventh leading cause of death in the United States and Canada. It is a chronic disorder of carbohydrate, fat, and protein metabolism. The disease starts off as a variety of metabolic changes that are associated with hyperinsulinemenia and hyperglycemia. When this happens, Insulin Resistance Syndrome results, which is a precursor to actual, full-blown, diabetes. If left untreated, insulin resistance will develop into full-blown diabetes, which includes greatly magnified risks of heart disease, stroke, eye and kidney disease, and loss of nerve function. It should be noted that diabetes is the principal cause of adult blindness and limb amputation.

Type 2 diabetes is the most common form of diabetes. In this type of diabetes, the body either does not produce enough insulin or the cells ignore the insulin. Insulin is crucial for the body to be able to use glucose for energy. The body breaks down all of the sugars and starches that you consume into glucose, while insulin takes the glucose from the blood into the cells. When glucose builds up in the blood instead of going into the cells, the cells may be starved for energy immediately, and high blood sugar glucose levels over time can cause damage to your eyes, kidneys, nerves, and heart. Diabetes occurs in people of all ages and races, with some groups having a higher risk for developing it than others. Diabetes is more common in African Americans, Latinos, Native Americans, and Asian Americans, as well as the older aged population.

Non-insulin-dependent diabetes, also known as type 2 diabetes, is a disease that is strongly associated with a sedentary lifestyle and the modern western diet. Inadequate physical activity, along with a diet that is high in refined sugars, saturated fats, and proteins, and simultaneously low in dietary fiber has resulted in an obesity epidemic throughout the United States and Canada. With this epidemic has risen the prevalence of type 2 diabetes. In fact, obesity is a main factor in type 2 diabetes, with almost 90% of those diagnosed with type 2 diabetes being obese at the time of diagnosis. Although there is still a disagreement as to whether obesity actually causes type 2 diabetes or whether diabetes causes obesity, there is one thing that is clear: the disease involves a huge disturbance to the metabolic balance of the body and weight is a major factor in blood sugar management. This disturbance leads to dramatic consequences for the individual.

In order to reduce the risk of type 2 diabetes, it is crucial that one prevents the onset of insulin resistance. Unfortunately, millions of North Americans unknowingly suffer from this syndrome. This places them at an increased risk for cardiovascular and neurological dysfunctions. Research has shown that complications that are associated with the development of insulin resistance may be mitigated effectively by conscientious dietary and lifestyle changes along with weight loss.

Vitamins B3, B6, B12, C, E, biotin, coenzyme Q10, and the trace elements chromium, magnesium, manganese, and zinc are all crucial for proper blood sugar defense and metabolic support, as well as the regulation of glucose metabolism. Supplementation with these nutrients at levels that are determined to be suitable for optimal nutritional health by cited nutritional authorities is an important part of product-rating criteria. Nutritional experts ask themselves whether the product in question contains vitamin B3, vitamin B6, vitamin B12, vitamin C, vitamin E, biotin, coenzyme Q10, chromium, magnesium, manganese, and zinc at potencies that are up to 100% of the potencies for these nutrients in the Blended Standard.

Excess weight seems to be a key factor in type 2 diabetes so it seems to reason that reducing body fat can help one improve insulin sensitivity. Losing weight is no easy task but is possible with consistent work. Fortunately, heath food stores have vitamin formulas that may help improve insulin sensitivity, but this is no substitute for good clean eating and exercise. For additional information on these supplements, please contact your local health food retailer.

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Antioxidants and your health
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Date: May 17, 2010 10:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants and your health

There is an impressive amount of scientific evidence supporting the health benefits of supplementing with a wide variety of antioxidants. Consequently, there are many health practitioners who have begun to recommend high dietary intakes of these crucial nutrients in order to prevent against oxidative stress. It was anticipated over two decades ago by leading researchers that high-dose supplementation with antioxidants is developing a significant role in the prevention and treatment of a lot of today’s common illnesses. It should be noted that antioxidants do not work in isolation. When an antioxidant neutralizes a free radical, it, itself, is oxidized and must be regenerated by another antioxidant before it can be used again. Because of this, it is crucial to supplement with a wide variety of antioxidants, in order to reflect what actually occurs in nature.

Vitamin C, an aqueous-phase antioxidant, is the main guard against oxidative attack in the extra-cellular matrix, as well as within the cytoplasm of the cell. Vitamin C happens to be a substrate for eight different enzyme systems that are involved in various cellular functions. Among these functions are collagen synthesis, ATP synthesis in the mitochondria, and hormone biosynthesis. Its main antioxidant partners are vitamin E and beta carotene, both of which help to regenerate vitamin C.

Of all the antioxidants, it seems as if vitamin E offers the greatest protection against heart disease because of its ability to protect the cardiovascular system from oxidative damage. It is lipid-soluble, making it an important component of the cell membrane, where it works to protect the cell against lipid peroxidation and control oxidation-induced inflammatory events. Recently, the gamma tocopherol form of vitamin E has shown a great deal of promise in its ability to reduce the risk of several oxidative stress related disease.

Beta-carotene is a member of a diverse group of photosynthetic pigments. It plays a huge role in human nutrition. As an antioxidant, it possesses a double-bond structure that allows it to react effectively with single oxygen radicals, absorbing and diffusing their energy. Beta-carotene also acts as a precursor for vitamin A by supplying a portion of the body’s requirement for the vitamin. This act alone plays a central role in the chemistry of vision. Beta-carotene and vitamin A both prevent the oxidation of cholesterol, reduce oxidative damage to DNA, and disable oxygen free radicals that are produced by exposure to sunlight and air pollution. These antioxidants are also involved in the activation of gene expression and the control of cell differentiation.

When combined together, vitamin C, vitamin E, and beta-carotene produce and important antioxidant trio that plays a huge role in fighting oxidative and inflammatory events. There are several other antioxidants that should be noted due to their ability to work synergistically with the vitamin C, vitamin E, and beta-carotene trio. These include vitamin A, alpha-lipoic acid, lycopene, coenzyme Q10, and the antioxidant mineral, selenium. In order to determine whether a nutrient provides antioxidant support, scientists question whether the product contains vitamin C, vitamin E, vitamin A, beta-carotene, alpha-lipoic acid, lycopene, coenzyme Q10, and selenium and to what strength these vitamins and minerals are per serving.

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it
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Date: February 25, 2010 09:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it

Aloe Vera Sunblock SPF30 LILY OF THE DESERTSunburn is the result of excessive exposure to the sun’s ultraviolet (UV) rays. The amount of exposure that is required to cause a burn is unique to each individual, the geographical location, the time, and the atmospheric conditions. There are two types of ultraviolet rays, which are designated as ultraviolet-A (UVA) and ultraviolet-B (UVB). Both types of ultraviolet rays are dangerous. UVB rays attack the skin’s outer layers, while UVA rays attack the underlying layers of the skin.

The majority of sunburns are first-degree burns that cause the skin to become red, warm, and tender to the touch. Depending on the severity of the burn and the individual’s skin type, the burn may subsequently “cool” into a suntan or thin layers of skin may peel off. More serious sunburn can be categorized as a second-degree burn. A second-degree burn consists of extreme reddening, swelling, pain, and even blisters. This is a sign that the burn has gone deeper than just the surface layer of the skin and has caused damage and the release of fluids from cells in the lower layers of the skin. The result of this is eruptions and breaks in the skin where bacteria and other infectious organisms can enter. In the most severe cases, a burn can be accompanied by chills, fever, nausea, and/or delirium. These types of sunburns are extremely painful and are extremely dangerous for children. Sunburn can often be accompanied by dehydration.

Those people who are fair-skinned are more prone to sunburn than those darker-skinned individuals. However, no matter what your skin color, you will burn if you get enough exposure. Symptoms do not always appear while you are in the sun, as they may begin from one hour to twenty-four hours after sun exposure and they usually reach their peak in two to three days. Natural Mineral Oil Free Sunblock SPF18 4 fl oz from ALBA BOTANICA

The effects of sun exposure are becoming an increasing concern today due to the decline in the earth’s ozone layer. The ozone layer is responsible for screening out the most harmful ultraviolet rays, but it is becoming increasingly thinner all over the world. Holes that fluctuate in size have even developed in various places. Additionally, the incidence of skin cancer is growing at an alarming rate. It has been found that having two or more bad episodes of sunburn as a child can make you much more likely to develop skin cancer as an adult.

The following nutrients are recommended for prevention and treatment of sunburn: coenzyme Q10, colloidal silver, DMB, a free-form amino acid complex, L-cysteine, a multivitamin and mineral complex, potassium, Pycnogenol, vitamin A with mixed carotenoids, vitamin C with bioflavonoids, an all-purpose bactericide spray, calcium, magnesium, essential fatty acids, silica, a vitamin B complex, vitamin E oil, and zinc.

Additionally, the following herbs may be beneficial in treating sunburn. Aloe vera gel has been noted to be remarkably effective in treating any kind of burn. It is responsible for relieving discomfort, speeding healing, and also helping to moisturize the skin and relieve dryness. A salve of calendula flowers and St. John’s wort can act as painkiller for burns and promote healing of skin wounds because these herbs have antiseptic properties.

Also, Lavender oil or chamomile oil used in a herbal bath can help to minimize the stinging and pain of sunburn. Comfrey and gotu kola tea can be made it to a compress for the affected area. Horsetail is good for tissue repair, while tea tree oil can help to heal sunburn and other skin irritation. Apple cider vinegar diluted with water is a great wash for sunburned areas.

To prevent sunburns, apply sunblock on any exposed skin before going out side to prevent skin damage before it starts.

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Herbs, Serrapeptase, and your Sinus
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Date: February 18, 2010 04:26 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbs, Serrapeptase, and your Sinus

sinus CavitiesSinusitis occurs when the nasal sinuses become inflamed. There are sinuses that are located above the eyes (frontal sinuses), inside the cheekbones (maxillary sinuses), behind the bridge of the nose (sphenoid sinuses), and in the upper nose (ethmoid sinuses). Sinuses are air-filled pockets in the skull that are connected to the nose and throat by passages designed to drain away mucous. The sinuses are the first line of defense to protect the lungs from infection. The majority of sinusitis cases affect the frontal and/or maxillary sinuses. However, any or all of the sinuses may be involved, with each individual tending to have problems with a particular set of sinuses. If the sinuses are too small or happen to be poorly position to handle the volume of mucous produced, they can become clogged. This causes pressure in the sinuses to increase, which causes pain. Those sinuses that are clogged for a long time are extremely prone to infection.

Sinusitis can be either acute or chronic. Acute sinusitis is usually caused by bacterial or viral infections of the nose, throat, and upper respiratory tract, like the common cold. Over 50 percent of all cases of sinusitis are caused by bacteria. Air travel can also lead to acute inflammation of the sinuses, due to the changes in air pressure. Chronic sinusitis problems, on the other hand, may be caused by small growths in the nose, injury of the nasal bones, air pollution, dental complications, emotional stress, smoking, and exposure to irritant fumes and smells. Allergic sinusitis may be the result of hay fever of food allergies, especially those allergies to milk and dairy products. People who have compromised immune systems are susceptible to fungal sinusitis, which is a potentially dangerous condition that requires aggressive treatment.

Sinusitis is characterized by symptoms such as fever which is usually low-grade but can be higher in some cases, cough, headache, earache, toothache, facial pain, cranial pressure, difficulty breathing through the nose, loss of the sense of smell, and tenderness over the forehead and cheekbones. If pain results from tapping the forehead just over the eyes, the cheekbones, or the area around the bridge of the nose, the sinuses may be infected. Sinusitis occasionally produces facial swelling which can be followed by a stuffy nose and a thick discharge of mucous. Those who suffer from sinusitis can have other unpleasant symptoms as a result of previous symptoms. Postnasal drip can cause a sore throat, nausea, and bad breath, while difficulty breathing can cause snoring and loss of sleep.Serrapeptase from Solaray

The following nutrients are considered to be helpful in dealing with and preventing sinusitis: acidophilus, bee pollen, flaxseed oil, a multivitamin and mineral complex, Quercetin, raw thymus glandular, vitamin A with mixed carotenoids, vitamin B complex, vitamin C with bioflavonoids, vitamin E, coenzyme Q10, colloidal silver, DMSO, garlic, MSM, proteolytic enzymes, Pycnogenol, sea mussel, serrapeptase, and zinc lozenges.

Additionally, the following herbs may be helpful in preventing and treating sinusitis: anise, fenugreek, marshmallow, red clover, bayberry, bitter orange oil, cat’s claw, ginger root, goldenseal, horehound, mullein, nettle, olive leaf extract, and rose hips. Serrapeptase is an enzyme that is able to help keep sinus fluid thin and flowing properly. Serrapeptase also possesses anti-inflammatory properties and can help reduce sinus inflammation which will ease pain and speed healing of the sinus cavity.

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Omega Red And Cholesterol
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Date: August 28, 2009 05:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega Red And Cholesterol

Red Omega™ With Red Yeast Rice, CoQ10 & Omega-3 Fish Oils in Softgels

Individually, Omega-3 fatty acids, CoQ10, and Red Yeast Rice extracts have each been shown in numerous studies to exhibit a wide range of cardio-beneficial properties. Until now, anyone interested in reaping the benefits of these three products had limited options, with the exception of purchasing multiple products. Red Omega™ has made it possible for today’s cardiovascularconscious health enthusiast to reap the benefits of all three compounds in one convenient dietary supplement.*

NOW® Red Omega™ is an innovative complex formula that was developed to help support healthy cardiovascular function. Omega-3 Fish Oil and CoQ10 have each been the focus of extensive research, and are now used by millions on a worldwide scope. Combined, however, they exert a powerful synergism that may potentially provide even greater health benefits. The organic Red Yeast Rice in this supplement is carefully produced to avoid the presence of citrinin, a sometimes toxic by-product of the fermentation process.*

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Thrombophlebitis
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Date: April 15, 2009 01:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Thrombophlebitis

Thrombophlebitis is when inflammation occurs in the veins due to the formation of a blood clot in that vein. This problem usually occurs in the extremities, especially the legs. Thrombophlebitis can be considered superficial if it affects the subsutaneous vein, which is one of the veins near the skin’s surface.

In superficial thrombophlebitis, the affected vein can be felt and may be seen as a reddish line under the skin. Additionally, swelling, pain, and tenderness to touch can occur. If widespread vein involvement is included, the lymphatic vessels may become inflamed. Superficial thrombophlebitis is a relatively common disorder that can be brought about by trauma infection, standing for long periods of time, lack of exercise, and intravenous drug use. The risk of superficial thrombophlebitis can be increased by pregnancy, varicose veins, obesity, and smoking. Thrombophlebitis can also be associated with environmental sensitivities to allergies. This condition is usually diagnosed according to physical findings and a medical history that indicates an increased risk.

Deep thrombophlebitis (DVT) affects the intramuscular veins farther below the skin’s surface. DVT is a much more serious condition than superficial thrombophlebitis because the veins affected are larger and located deep within the musculature of the leg. These veins are responsible for the transport of 90 percent of the blood that flows back to the heart from the legs. Symptoms of DVT may include pain, warmth, swelling, and bluish discoloration of the skin of the affected limb. These symptoms are often accompanied by fever and chills. The pain is typically felt as a deep soreness that is worse when standing or walking and gets better with rest, especially with elevation of the leg. The veins directly under the skin may become dilated and more visible. Inflammation situated in a vein in the pelvis is referred to as pelvic vein thrombophlebitis.

The reason or reasons for the formation of the clots in the veins are often unknown. However, in most cases, clots are probably the result of a minor injury to the inside lining of a blood vessel. If the vessel lining receives a microscopic tear, clotting is initiated. Platelets clump together to protect the injured area, and a series of biochemical events is initiated that results in the transformation of fibrinogen, a circulating blood protein, into strands of insoluble fibrin, which are deposited to form a net that traps blood cells, plasma, and yet more platelets. This results in a blood clot. Other possible causes of the formation of DVT include abnormal clotting tendencies; poor circulation; certain types of cancer; and Behcet’s syndrome, which is a condition that affects small blood vessels that predispose an individual to the formation of clots. The following factors increase the risk of DVT: recent childbirth, surgery, trauma, the use of birth control pills; and prolonged bed rest.

The following nutrients are recommended for the prevention and treatment of thrombophlebitis: acetyl-l-carnitine, coenzyme Q10, flaxseed oil, garlic, l-cysteine, lecithin granules, l-histidine, magnesium, MSM, Pycnogenol, vitamin C with bioflavonoids, vitamin E, zinc, and vitamin B complex. Additionally, the following herbs may be beneficial: alfalfa, pau d’arco, red raspberry, rosemary, yarrow, butcher’s broom, cayenne, ginger, plantain, witch hazel, skullcap, valerian root, ginkgo biloba, goldenseal, hawthorn, and olive leaf extract.

Natural vitamins are a great way to help prevent conditions such as these. If you suspect that you have thrombophlebitis, consult your doctor before trying to take the problem into your own hands. Natural vitamins such as the ones listed above can be found at your local or internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Vitamins and Herbs
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Date: April 03, 2009 02:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamins and Herbs

The whole human body is made up of cells that contain their own genetic material. In a healthy body, these cells divide at a controlled rate, growing and repairing damaged tissues and replacing dying cells. This predetermined rate of cell division is what keeps our bodies healthy. If cells keep multiplying when new ones are not necessary, a mass of tissue, often known as a tumor, is formed. This tumor can be either benign or malignant.

Benign tumors are not cancerous and can occur anywhere in the body. Benign tumors do not cause a threat to health, do not metastasize, and do not grow back if removed. Malignant tumors are cancerous and are usually serious. Often times, they can be life-threatening. Malignant tumors grow uncontrollably, interfere with normal metabolic and organ functioning, and have the ability to metastasize and invade other tissues. If a portion of a cell’s DNA is damaged, the cell can become abnormal. When an abnormal cell divides, it forms new cells that are a photocopy of the damaged genetic material. This ongoing process occurs constantly within our bodies. The majority of the time our bodies have the ability to destroy these abnormal cells and maintain a sort of cellular equilibrium. If a crucial part of the DNA is destroyed and the abnormal cells cannot be controlled any longer, cancer forms. All cancer cells have two things in common: growing uncontrollably and having the ability to metastasize. The immune system does not recognize cancer cells as dangerous or foreign.

Although the exact cause for the cell damage that initiates the cancer process is unknown (theoretically free radical damage causes DNA damage), the chain of events that leads to cancer is very complex, and each individual body reacts differently. It is a combination of genetic, behavioral, environmental, and lifestyle factors that are thought to be involved in turning normal cells into abnormal cells, and abnormal cells into cancer.

There are also factors that are believed to slow the process, while other factors can speed up the process. Possible contributors to the development and growth of cancer can be divided into three categories: external, internal, and lifestyle. External factors include unhealthy workplace environments and exposure to air and water pollution, chemicals, pesticides, and herbicides. Included in the internal factors include both genetics and infections. Lifestyle factors are those we personally can most readily control, such as diet, smoking, drinking, and sun exposure. External and lifestyle factors account for 80 percent of cancer deaths in the United States.

Just as each of us looks different, each of our bodies has its own unique composition. Some of us may react adversely to what some of us react well to. This is why some treatments prove to be successful for some, but not for others. This is why dietary wellness and prevention is so important. If we can keep our bodies healthy and avoid known cancer-causing agents, we have a good defense against cancer in the first place.

The following nutrients and supplements are designed for persons who have been diagnosed with cancer, as well as for those who wish to enhance their chances of avoiding the disease: coenzyme Q10, colostrum, DMG, garlic, IP6, melatonin, MSM, proteolytic enzymes, selenium, 7-keto DHEA, shark cartilage, SOD, vitamin A, shiitake extract, acidophilus, chromium picolinate, flaxseed oil, grape seed extract, kelp, l-carnitine, multienzyme complex, a multi-mineral complex, multivitamin complex, NAC, raw glandular complex, taurine, and vitamin B complex. Additionally, the following herbs may be beneficial: astragalus, birch, burdock root, cat’s claw, chaparral, chuchuhuasi, cranberry, dandelion, Echinacea, fennel, green tea, licorice root, macela, milk thistle, parsley, pau d’arco, red clover, suma, cardamom, cayenne, ginger, rosemary, sage, thyme, turmeric, ragwort, wood sage, curcumin, essiac, noni, olive leaf extract, rosemary, and boswellia.

All of the above listed herbs and vitamins can help restore the body to good nutrition and help boost the immune system so the body can find and fight back against cancer. Natural vitamins and herbs are available at your local or internet health food store. When purchasing supplements, look for name brand vitamins like Solaray and Source Naturals to ensure you receive quality and you get what you pay for.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.



--
Vitanet ®, LLC

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Phytoestrogen
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Date: March 27, 2009 01:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Phytoestrogen

Menopause is the time at which a woman stops ovulating and menstruation ceases, which indicates the end of fertility. Menopause is not a disease, but rather a natural progression in life, similar to puberty. Many years before a woman stops ovulating, her ovaries will begin to slow their production of the hormones estrogen, progesterone, and testosterone. Estrogen and progesterone are often thought of as the reproductive hormones.

Although estrogen is essential in reproduction, it is also extremely important in other non-reproductive organs and systems in the body. Cells in the uterus, bladder, breasts, skin, bones, arteries, heart, liver, and brain all contain estrogen receptors. These organs need this hormone in order to stimulate these receptors for normal cell function. Estrogen is needed to keep the skin smooth and moist and the body’s internal thermostat working properly. Estrogen is also essential for proper bone formation. Even though estrogen levels drop sharply after menopause, they do not disappear entirely. Other organs take over for the ovaries, continuing to produce a less potent form of estrogen. These organs, known as endocrine glands, secrete some hormones from fatty tissue in order to maintain bodily functions.

Progesterone works along with estrogen, stimulating changes in the lining of the uterus to complete the preparation for a fertilized egg during the second half of the menstrual cycle. If no egg is fertilized, the uterine lining is broken down and expelled, allowing the cycle to being again. Progesterone also has effects beyond the reproductive system, as it calms the brain and also affects other aspects of nervous system function. Testosterone is most important for both men and women, with women producing about 80 percent less than men do. However, it is the driving force for maintaining a healthy life and proper functioning organs.

The period when a woman’s body is preparing for menopause is known as perimenopause. For the majority of women, hormone production beings to slow down then they reach their thirties, continuing to diminish with age. Many women will experience few if any symptoms at this time, but others may suffer from anxiety, dry skin, fatigue, feelings of bloating, headaches, heart palpitations, hot flashes, insomnia, irritability, decreased interest in their significant other, loss of concentration, mood swings, night sweats, reduced stamina, urinary incontinence, uterine dryness and itching, weight gain, cold hands and feet, joint pain, hair loss, and/or skin changes.

Menopause occurs when a woman stops menstruating altogether. At this point, most of the acute problems a woman may have experienced are actually over and a new balance between all hormones should be established. However, women become increasingly vulnerable to other, potentially serious health problems at this time. Over the long term, the diminished supply of estrogen increased the likelihood of cardiovascular disease, osteoporosis, and uterine atrophy. Osteoporosis especially is a major problem for women after menopause, with an estimated 80 percent of the hip fractures that occur in the United States every year being due to osteoporosis.

A proper diet, nutritional supplements, and exercise can help to minimize or eliminate most of the unpleasant side effects of menopause. The following nutrients are recommended for dealing with this stage of life: beta-1, cerasomal, coenzyme Q10, DHEA, essential fatty acids, lecithin granules, a multi-enzyme complex, soy protein, vitamin B complex, vitamin D3, vitamin E, boron, calcium, magnesium, quercetin, silica, zinc, l-arginine, multiglandular complex, a multivitamin and mineral complex, vitamin C, aloe vera gel, slippery elm, damiana, amaranth, chickweed, dandelion greens, nettle, seaweed, watercress, anise, black cohosh, fennel, licorice, raspberry, sage, unicorn root, wild yam root, hops, valerian root, gotu kola, red clover, dong quai, St. John’s wort, and Siberian ginseng.

All these above listed vitamins and herbs are available in capsule, tablet, or powder forms. When looking for natural alternatives to help replace estrogen naturally, look to your local or internet health food store for name brand products that can help restore an imbalance over time.

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Psyllium Husk Fiber
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Date: March 18, 2009 12:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Psyllium Husk Fiber

Hemorrhoids occur when veins in the anus and in the rectum swell and may protrude from the anus. The word hemorrhoid comes from the word hemo which means blood and rrhoids which means discharging. Hemorrhoids are also known as piles, which comes from the Latin word pila, meaning ball. Hemorrhoids are a lot like varicose veins, as they enlarge and lose their elasticity. This results in a saclike protrusion into the anal canal. Hemorrhoids are not tumors growths. Instead, they can be caused and aggravated by sitting or standing for prolonged periods, violent coughing, lifting heavy objects, and straining at bowel movements. This occurs especially when constipated.

However, bouts of diarrhea accompanied by involuntary spasms can further the problem. Other factors that contribute to the formation of hemorrhoids include obesity, lack of exercise, liver damage, food allergies, and insufficient consumption of dietary fiber. Hemorrhoids are extremely common during pregnancy and after childbirth, with hormonal changes and pressure exerted by the growing fetus are a huge being the main reason. About half of all Americans have had hemorrhoids by the age of fifty, with the incidence increasing with age until age seventy, and then decreasing again.

The most common symptoms of hemorrhoids include itching, burning, pain, inflammation, swelling, irritation, seepage, and bleeding. The bleeding can be startling or even frightening, as it is usually bright red during bowel movements. Although it does signal that something is slightly off in the digestive system, rectal bleeding is not necessarily an indication of a serious disease.

There are three different kinds of hemorrhoids, which are categorized depending on their location, severity, and the amount of pain, discomfort, or aggravation that they cause. These three types include external, internal, and prolapsed.

External hemorrhoids develop under the skin at the opening of the anal cavity. They may form a hard lump and cause painful swelling if a blood clot forms. When an external hemorrhoid swells, the tissue in the area becomes firm but sensitive and often turns blue or purple in color. Most often, this type of hemorrhoid affects younger people and can be extremely painful.

Internal hemorrhoids, which are located inside the rectum, are usually painless, especially if they are located above the anorectal line. This is because rectal tissues lack nerve fibers. However, internal hemorrhoids tend to bleed, with blood appearing to be bright red.

Prolapsed hemorrhoids are internal hemorrhoids that collapse and protrude outside the anus. These are often accompanied by a mucous discharge and heavy bleeding. Prolapsed hemorrhoids often become thrombosed, forming clots within that prevent their receding. Thrombosed hemorrhoids can also be extremely painful.

To our knowledge, hemorrhoids are unique to human beings, with no other creature developing this problem. This can be taken as an indication that our dietary and nutritional habits play a greater role in this disorder than anything else. About 50 to 75 percent of this country’s population develops hemorrhoids at one time or another, with many people being unaware of them. Hemorrhoids can occur at any age, but they tend to become more common as people grow older. Those younger people, pregnant women, and women who have had children seem to be most susceptible, with heredity also playing a part in the tendency to develop hemorrhoids. Although hemorrhoids can be quite painful, they usually are not a serious threat to our health.

The following nutrients can help prevent and treat hemorrhoids: calcium, vitamin C with bioflavonoids, vitamin E, vitamin B complex, coenzyme Q10, DMG, garlic, potassium, shark cartilage, vitamin A, and vitamin D3. Additionally, the following herbs are also beneficial: aloe vera gel, bayberry, goldenseal root, myrrh, white oak, comfrey root, elderberry, yarrow, witch hazel, buckthorn bark, collinsonia root, parsley, red grape vine leaves, and stone root.

Looking at that list one might think wow that could be expensive. Fortunately, the single most important factor to prevent hemorrhoids is fiber. Adding dietary fiber to ones diet can eliminate constipation and all the complications that follow with bowel problems. Fiber supplements can be an easy solution to the lack of fiber on ones diet. Psyllium husk is a natural fiber that can be taken daily to help alleviate constipation and is relatively inexpensive. Fiber supplements are available at your local or internet health food store.

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Migraines
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Date: February 21, 2009 12:33 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Migraines

Migraines are severe, throbbing headaches that may or may not be accompanied by nausea, possibly with visual disturbances and other symptoms. Migraine incidences have increased by 50 percent within the last twenty years, with an estimated 25 to 30 million people suffering from them in the United States. Three out of four of these 25 to 30 million are women, with up to 24 percent of women experiencing at least one migraine in their lives and only 12 percent of men getting migraines. Migraine headaches are one of the most severe types of headache.

Research has described migraines as vascular headaches, as they involved excessive dilation or contraction of the brain’s blood vessels. Current research, however, gives other clues. The inflammation involved in migraines is most noticeable in the meninges, which surround the brain and the spinal cord. However, the inflammation of the meninges is not what leads to the pain of migraine, but instead abnormal nerve activity. Stimulation of the trigeminal nerve, which goes from the brain to the head and face, triggers the release of substances that are known as calcitonin gene-related peptides. These induce inflammation and send messages to pain receptors in the meninges. Some researches even liken migraines to meningitis in some ways, as the symptoms are very similar. However, meningitis is caused by viral or bacterial infection.

Migraines can occur anywhere from once a week to once or twice a year, often running in families. One factor that may contribute to the higher incidence of migraine in women may be fluctuations in the level of the hormone estrogen, as women typically get migraines around the time of menstruation, when estrogen levels are low. Most often, migraines occur in people between the ages of twenty and thirty-five, seeming to decline with age. Children can also suffer from migraines, with pain tending to be more diffuse, rather than localized. Migraines can first show up in childhood as colic, periodic abdominal pain, vomiting, dizziness, and severe motion sickness, rather than as headaches.

There are typically five phases in a migraine. The first phase beings a day or so before the onset of a headache, as changes in mood, problems with memory, an alteration in one or all of the five senses, and speech problems occur. Secondly, some people will see flashes or patterns of light and experience numbness of the hands and mouth just before the headache. This is called an aura, and is a common sign of a classic migraine.

Those migraines that occur without auras are called common migraines. The third phase occurs when the headache starts with a severe, throbbing pain occurring on one or both sides of the head and can also move from side to side. Nausea can also set in this phase, along with tenderness in the neck and scalp, sensitivity to light, and possibly immobilization due to pain. The fourth phase occurs when the headache dissipates, although nausea may linger. During the fifth phase, the person may feel tired and lethargic, simply wanting to sleep.

A variety of things can trigger a migraine in an individual who is susceptible, including allergies, constipation, stress, liver malfunction, too much or too little sleep, emotional changes, hormonal changes, sun glare, flashing lights, lack of exercise, and changes in barometric pressure. Dental problems and low blood sugar can also be factors, while other underlying causes such as genetic factors, chemical imbalances in the brain, poor nutrition, and the overuse of painkillers can cause an individual to be susceptible to migraines. Block Migraines with vitamins and herbs.

The following nutrients are recommended for preventing and dealing with migraines: calcium, magnesium, coenzyme Q10, DMG, DLPA, essential fatty acid complex, 5-HTP, a multivitamin and mineral complex, rutin, vitamin B complex, garlic, quercetin, taurine, vitamin C with bioflavonoids, cordyceps, feverfew, ginkgo biloba, cayeene, chamomile, fumitory, ginger, peppermint, rosemary, valerian, willow bark, and wormwood.

If you are experiencing migraines, consult your doctor before starting vitamin supplements. Vitamin supplements are natural and feed the body to make it stronger and capable of fighting the diseases it may come up against, but medications prescribed by your doctor can conflict with certain vitamins and herbs and a doctors consultation is needed when taken with medications. A source of natural vitamins are available at your local or internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Hay Fever
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Date: February 19, 2009 05:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hay Fever

Hay fever, which is an allergy to proteins in the pollen of trees, grasses, some plants, or mold, affects the mucous membranes of the nose, eyes, and air passages. Symptoms of hay fever include itchy, red eyes; watery discharge from the nose and eyes; sneezing; fatigue; and nervous irritability. Many of the symptoms of hay fever can be confused with those symptoms of the common cold. However, allergies cause a distinctive clear, thin nasal discharge, whereas secretions that come from colds are usually thick and yellow-greenish as the illness progresses. Colds are also associated with mild fever and are usually gone within a week. On the other hand, allergy sufferers often feel wiped out for many weeks.

At least 50 million Americans suffer from seasonal sneezes, runny nose, and itchy eyes that come with hay fever. There happen to be three seasons of hay fever which are distinguished by the different pollen present at these different times of the year. Tree pollen appears first, usually between February and May, depending on the climate. When trees, weeds, grass pollens, and people are out at the same time, the biggest problems arise. This usually occurs later in spring and in summer. The fall is the season for ragweed pollen. Depending on which pollen or pollens an individual is allergic to, hay fever may be present at any or all of these times.

In more detail, the following is a summary of the types of plants according to the times of year they are most likely to cause problems. Alder, hazelnut, and elm trees cause the most problems in February through May, while birch, maple, and oak trees are problematic in March through June. Beech and spruce trees bring about issues in April through June, while horse chestnut trees are responsible for causing problems in April through August. In April through September, Asters, pine trees, plantain, sorrel, stinging nettle, and various grasses are responsible for bringing about allergies. Buttercups are problematic in May through July and Goosefoot is an issue in June through September. In July through September, mugwort seems to pose a problem.

Those people who suffer from hay fever also often suffer from other atopic disorders like asthma and dermatitis. Those people who suffer from hay fever symptoms throughout the year are said to have perennial rhinitis, which can be caused by animal hair, dust, feathers, fungus spores, molds, and/or some other environmental agent. It should be noted that a susceptibility to hay fever tends to be an inherited condition. Those people who are most prone to allergies are often aware of the time of year and conditions under which they are most sensitive. A RAST test can easily be done and provide reliable results for a definitive diagnosis.

The following nutrients are beneficial for hay fever: bromelain, coenzyme Q10, Quercetin, raw thymus, vitamin A, vitamin B complex, vitamin C with bioflavonoids, proteolytic enzymes, zinc, calcium, magnesium, garlic, kelp, manganese, Pycnogenol, SOD, and vitamin E. Additionally, the following herbs have been noted to be helpful: alfalfa, chlorophyll, vitamin K, eucalyptus oil, eyebright, lady’s mantle, goldenseal extract, horehound, mullein leaf, stinging nettle, wild cherry bark, turmeric, nettle leaf, and noni juice.

In conclusion, discovering your allergic substance is the first step to recovery. When you can narrow down what is the cause then you can combat the problem with vitamins, herbs, and dietary changes. Your local or internet health food store has a large selection of herbal and homeopathic remedies for hay fever symptoms.



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Ubiquinol Reduced CoQ10
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Date: April 07, 2008 01:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol Reduced CoQ10

Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.

Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.

In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.

CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.

While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.

In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.

A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.

As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.

The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.

Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.

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Alpha Lipoic Acid is a Powerful Antioxidant
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Date: February 15, 2008 02:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Alpha Lipoic Acid is a Powerful Antioxidant

The discovery of alpha lipoic acid at the University Of Texas Chemistry Department in 1951 was not heralded with trumpets of joy at the revelation of such a powerful antioxidant, but was instead largely ignored. This is largely due to the biochemistry involved not being fully understood at that time, but by the 1980s it was a commonly used supplement, recommended for several medical conditions.

Chemically, the substance is a 5-membered cyclic disulphide with a carboxylic acid grouping. Biochemically, it’s extremely powerful antioxidant properties are largely due to the fact that it one of those rare active molecules that are soluble in both water and fats, and in fact is the only such antioxidant currently know. One of the properties that this ability enables it to possess is to cross the blood-brain barrier, and apply antioxidant propertied to the brain.

Antioxidants are essential to human life in that they destroy free radicals. These are compounds with free unpaired electrons that destroy human body cells in their hunt for electrons to pair with. Electrons come in pairs in organic animal tissue, just as they do in organic compounds. However, under certain circumstances this pairing can become destroyed, leaving a molecule with one of its electrons without a partner.

The factors that lead to this situation are many and varied, and our own biochemistry can produce free radicals during the normal chemical processes of life. However, pollution can also lead to the oxidation processes that create free radicals, common such pollutants being cigarette smoke, vehicle exhaust fumes, pesticides and the like. Excessive exposure to the UV content of sunlight can also create free radicals as can eating barbecued and smoked foods, and exposure to carbon monoxide and peroxides. Even the biochemical conversion of glucose to energy in our bodies creates free radicals.

These free radicals can destroy body cells, including DNA, and can create conditions such as premature aging due to destruction of skin cells, destruction of brain cells, strokes, cancers, diabetes, atherosclerosis due to oxidation of LDL cholesterol that deposits in the main arteries of the body, stiffening of the joints and many other undesirable conditions.

Free radicals are destroyed rapidly by antioxidants: the reaction is very rapid and most are destroyed immediately they are formed before they can do harm. Fortunately, if your diet is well maintained, the body possesses many antioxidants such as vitamins A, C and E, and other substances such as Coenzyme Q10, flavanoids, xanthenes, polyphenols and carotenoids. Many of these are found in highly colored foods, and if your food is brightly colored, it should contain a good supply of antioxidants.

However, the problem with all of these is that they are either fat and oil soluble or water soluble, which means that they can either be freely carried round the body by the blood or have to be emulsified by the bile and transported via the lymphatic system that places restrictions on their effectiveness in certain organs of the body. The fact that alpha lipoic acid is soluble in both water and fats enables it to be carried to all parts of the body and to every organ, and can cross water/fat barriers that other antioxidants cannot do.

It can therefore be carried via the blood to the brain and carry out an essential antioxidant function within our brains. It took a long time for this property of ALA to be recognized and its consequent health benefits understood. It is, in fact, the ideal antioxidant. The substance provides many known benefits to the body due to its antioxidant properties and also helps the body to generate the maximum possible amount of energy from the blood glucose and thus improve the energy balance of your body.

However, it is with its antioxidant properties that we are most concerned here. One of the benefits of these properties is its effect in holding back the visible effects of aging on your body. Because it is both water and fat soluble, alpha lipoic acid can help destroy free radicals in every part of your skin; the areas served by the blood and the fatty and oily secretions are protected simultaneously by the same strong antioxidant. The end result is a reduction in the destruction of the cells through the dermis and epidermis and a reduction in the degree of wrinkling with age.

Its antioxidant effect in the brain renders ALA in great demand for reducing cognitive impairment with age. In fact studies have indicated that alpha lipoic acid can improve memory and brain function in the aging and the elderly. This effect appears to be increased by the synergistic combination of alpha lipoic acid and acetyl-L-carnitine that work together to prevent cognitive decline in the brain through the effect of free radicals.

There is evidence that during a stroke, ALA works synergistically with vitamin E to reduce the effect of free radical damage on the vulnerable brain cells, and so reduce the longer term effects of the stroke. Together with ALC, it also reduces oxidative stress on the mitochondria of cells and in so doing helps once again to reduce the effects of aging, and maintain the body’s capacity to generate energy from blood glucose.

Cardiovascular disease is the main killer of the western world, largely due to our diets, and this is especially true of the USA. Although Americans appear unable to change their unhealthy diet, alpha lipoic acid and acetyl-L-carnitine can be used to offset much of the damage done. ALA reduces the development of atherosclerosis through its antioxidant properties and the reduction of the adhesion of monocytes to the artery walls.

LDL trapped in the wall of the artery can be oxidized and enable monocytes to also enter under the surface of the arterial wall, where it changes into macrophages and ingests the oxidised LDL, causing the plaque that forms atherosclerosis. As the plaque thickens, the artery becomes increasingly restricted until the blood flow is significantly reduced or even stopped, causing cardiac failure or a stroke.

Alpha lipoic acid can prevent this free radical oxidation from occurring by destroying them before they act on the low density lipoprotein (LDL). Acetyl-L-carnitine works with the ALA to achieve this, as does another substance known as carnosine. Between them, these three musketeers work to keep your arteries clear and your brain functioning as it should, though it is the ALA that is most powerful due to its oil and water solubility properties.

Although alpha lipoic acid is available as a supplement, either alone or in combination with acetyl-l-carnitine, it is also available from natural food sources. It is particularly rich in offal such as heart and kidney, and also in broccoli, spinach and brewer’s yeast. It is also available in beef, and it is here that burgers can perhaps repay some of the damage that it causes. However, it is not a recommended source since burgers still cause more damage to your health than any of their constituent nutrients can allay.

Like any other supplement, you should seek medical advice before taking any substance if you have a health condition. Nevertheless, the benefits of alpha lipoic acid are such that it is difficult to see it doing anything but good. However, please consult your physician if are taking other drugs.

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Seniors Need More Than a Multiple with Only 100 Percent of the RDA
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Date: January 21, 2008 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Seniors Need More Than a Multiple with Only 100 Percent of the RDA

The aging process is a gradual one. That might seem obvious, and it is, but it is the fact that it is gradual that causes people not to notice the small but significant changes in their body that are taking place. Aging is more than just the oxidation of skin cells that cause them to wrinkle, but involves specific functional cell changes, such as their ability to multiply.

As this slows down the immune system is affected, and we find it more difficult to recover from injury and disease. Oxidation becomes more prevalent and free radicals become more common as the natural antioxidants of our bodies become overwhelmed. We are less able to recover from the effects of environmental stress, such as UV radiation from the sun, pollution and the effects of heat. We find it increasingly difficult to deal with a lack of nutrition or toxins in our food from pesticides. In short, we become less capable of dealing with attack by invaders, but do not notice this gradual lack of immune response.

Age also affects our joints from the vertebrae in the neck to the joints of our toes. The net result is a compression of the bones that causes a reduction in height. We also develop more body fat and less muscle tissue, which is a significant consideration in planning the nutritional needs of the elderly. However, of more critical importance when discussion the nutritional needs of our aging population is the possibility of malabsorption.

Malabsorption is an inability of the digestive system to absorb nutrients from food, and occurs in people of any age although it tends to be more prevalent in seniors. It is predominantly due to a dysfunction of the liver, the pancreas or the small intestine that are the three major physical components of the human digestive system.

The liver produces bile that is needed to process the fats in your food, and if the bile is not delivered to the small intestine, then malabsorption is possible. The same is true of the enzymes that are produced by the pancreas These enzymes are important components in the biochemistry that allow us to absorb nutrition from our food, and since most of this absorption occurs in the small intestine, this too is essential for proper absorption. When any of these three are reduced in efficiency, as they are with advancing years, then malabsorption will occur.

When this occurs in seniors, however, it is essential that a multiple supplement with more than 100% of the RDA (Rcommended Daily Allowance) is used. This type of nutritional deficiency can be very serious at an age when so many normal biochemical processes are slowing down, and it is important that steps are taken to avoid the serious problems that can arise.

The immediate symptoms of malabsorption are diarrhea and weight loss, although the more serious longer term effects are anemia due to a deficiency in folic acid and iron and a reduction in the blood’s ability to form clots due to a deficiency in vitamin K absorption. There are others, but not all problems associated with aging are actually due to malabsorption, or even with aging.

Many of the problems associated with aging are now believed to be connected with the patient’s lifestyle and diet. Heart disease such as atherosclerosis is now known to begin earlier in life, as are many other conditions once believed to be associated with age. A loss of cognitive ability can be age related, but also due to cigarette smoking and excessive alcohol consumption. However, irrespective of all this, it is essential that the aged are provided with vitamin and mineral supplements offering more than 100% RDA.

Calcium is of particular importance for older women who are particularly prone to osteoporosis due to malabsorption of calcium from their food. At least 1000mg daily should be taken, and extra magnesium and vitamins A and E will also be necessary since they are needed for the proper absorption of calcium. The extra does not infer that all of the supplement will be absorbed, but that enough should be to help reduce the possibility of bone density problems.

The elderly are particularly prone to vitamin B deficiencies, particularly of vitamin B12, due to absorption problems and a good vitamin B complex supplement is needed. Chromium too can be seriously depleted in the aged, and this mineral is necessary to enhance the activity of insulin. It is also believed to play a part in the metabolism of carbohydrates, proteins and fats. There are no known consequences of an excess of chromium so a good supplement can be provided. It is believed that vitamin B and chromium together are required for cardiovascular and neurological health that are so important as we age.

One important supplement for the elderly is Coenzyme Q10. Many older people are prescribed drugs such as statins for the treatment of high cholesterol levels. Statins work by depressing the biochemical synthesis of cholesterol by blocking the action of mevalonate, and this is known to interfere with the metabolism of Coenzyme Q10, otherwise known as ubiquinone.

CoQ10 is essential in allowing the production of energy within the cell mitochondria by allowing electron transfer back and forth between NAD and NADH to allow the production of adenosine triphosphate (ATP). A supplement of this important enzyme is therefore essential in maintaining the energy levels of the aged who are being prescribed statins.

Almost 20% of the elderly on prescription drugs are also taking herbal remedies and supplements, and there could be an interaction between them. Anybody taking prescription drugs should consult their physicians before taking natural remedies or any form of supplement, and this is particularly true of the elderly.

However, where the elderly are safely taking a vitamin and mineral supplement, it is extremely important that this contains more than just the RDA. Absorption problems are very common in the elderly, and this excess can make sure that they receive more than they would otherwise, if not the whole recommended dosage of the particular substance involved. Better safe than sorry, especially where an excess is not known to cause harm.

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Give Your Health A Boost With Silica Hydride A Powerful Antioxidant
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Date: January 18, 2008 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Give Your Health A Boost With Silica Hydride A Powerful Antioxidant

Hydride ions are strong proton acceptors and hence fatal to free radicals. Silica hydride is consequently a powerful antioxidant that can be used to protect your body against the ravaging effects of these free radicals that destroy the cells of your body, and due to its other unique properties this is a molecule that could be a very useful participant in the various redox reactions that occur naturally within our bodies every microsecond of every day of our lives.

A free radical is a positively charged molecule that is deficient in an electron. Whereas stable compounds consist of electron pairs, a free radical consists of electron pairs and one unpaired electron. Although such a compound is not stable, it does not immediately disintegrate but grabs the nearest electron it can find. This would normally be an electron in the nearest body cell to it, whether it is a blood cell, a cell in an artery wall or a skin cell. The result is that the cell that loses the electron is disrupted.

Free radicals are formed in the body through its normal biochemistry, and also promoted by pollutants such as cigarette smoke, pesticides and traffic fumes. Excessive exposure to the ultraviolet radiation of sunlight or sunbeds also creates free radicals, as does excessive exercise, believe it or not. As stated earlier, these chemicals have only one purpose in your body: to grab an electron from wherever they can, and in doing so they destroy the cells that make up your body tissue.

This can lead to premature aging, heart disease and many other problems with your health. Antioxidants such as vitamins C and E are important parts of your diet, and silica hydride is an other supplement which has been relatively recently discovered to have antioxidant properties. A component of glacial streams, this substance is generally in colloidal form, or in the form of small particles maintained in suspension by the interaction of positive and negative charges on the surface of the tiny particles of which it consists.

The interface between the silica and water can be saturated with reduced hydrogen to form a surface that is overall negatively charged and can hence neutralize free radicals that are seeking the free electrons available from the negative charge. This is otherwise described as a reducing or anti-oxidant effect. All anti-oxidants play their part in neutralizing the properties of free radicals that result in the destruction of body cells.

This leads to premature aging of your skin, if a skin cell is affected, if it is a cell in your artery wall, then the artery will become damaged, and if a blood cell then you can suffer from any one of a number of abnormal blood conditions. The stealing of an electron from one molecule by another is scientifically termed 'oxidation', and the substances that prevent this from occurring are called antioxidants, or reducing agents.

An antioxidant will destroy free radicals by providing the extra electron, or chemically, a negatively charged hydrogen ion. This occurs practically instantaneously, in microseconds in fact, as soon as the free radical is formed, so you need a good supply of antioxidants in your body at all times. Free radicals do not roam your bloodstream looking for likely candidate cells to destroy – they do it right away with the nearest available, so antioxidants must be present at the time that the free radicals are created.

Other beneficial effects of such antioxidants are an increase in the potential for the mitochondria to generate energy within your cells, an increase in the hydration of body cells and a decrease in lactic acid build–up that occurs as the result of exercise. The negative charges of silica hydride atoms are very strong antioxidants and can dramatically increase the energy production of mitochondria. It has been shown to do so by up to six times in Chinese hamsters. There is more on this claim for such a significant effect on your energy production later.

In addition to its action as an antioxidant, silica hydride is an electron donor to other antioxidants that have been neutralized by reaction with a free radical. When antioxidants do their work they are not destroyed, but neutralized. They act by giving an electron to the free radical, and are then one electron deficient themselves. This could virtually turn them into free radicals also were it not for the other electron donors available. Silica hydride is one of these. Thus, Coenzyme Q10, another very powerful antioxidant, can have is potency regenerated by silica hydride. If you take a silica hydride supplement, you are not only taking an effective antioxidant, but also a substance that can recharge the batteries of other powerful antioxidants.

Another side effect of this substance is that the reacted hydrogen atoms can also be used in the body to maintain a slightly alkaline pH which is an additional health benefit. pH is a measure of the acidity and alkalinity of the body fluids, and should be maintained slightly alkaline, other than in the stomach where the digestive juices are strongly acidic.

Silica hydride is not essential to the body, so you cannot suffer from a deficiency of it. It is not known to be contained in any foodstuff or water source, and appears to be available only as a supplement. Consequently no optimum dosage has been determined, though the supplements available contain from 200 to 250 mg per capsule. Likewise, side effects from it are unknown since there have been few scientific studies carried out on it. It has, however, been described as the ‘perfect antioxidant’.

Some of the claims made for the substance include reducing lactic acid concentration during exercise. Lactic acid production during exercise causes tiredness and cramps, and silica hydride is said to increase the body’s production of adenosine triphosphate (ATP) a substance essential for the production of energy in your body. This is through the reduction of nicotinamide adenine dinucleotide (NAD) to the reduced form NADH as a part of glycolysis and the citric acid cycle. Glycolysis is the metabolism of glucose to energy by the mitochondria.

If the claim that silica hydride effects this reduction of NAD to NADH six or seven times stronger than normal were true, then it would indeed be a significant energy booster invaluable to most athletes.



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Support Healthy Joint Function With Discount Vitamins
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Date: November 22, 2007 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Support Healthy Joint Function With Discount Vitamins

The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime.

Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones.

Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain.

Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue.

A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders.

A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints.

The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover.

Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids.

Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks.

Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage.

Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement.

It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that.

That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results.

Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density.

There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium.

You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.



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Ubiquinol
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Date: October 24, 2007 11:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

Benefits

Ubiquinol has powerful antioxidant actions in target cells *

 

Although ubiquinone (oxidized coenzyme Q10) and ubiquinol (reduced coenzyme Q10) are kept at a constant ratio within the body, the majority of the total coenzyme Q10 pool is made up of ubiquinol.  In fact, when ubiquinone is taken orally, much of it appears to be rapidly converted into ubiquinol. 1,4 Ubiquinol functions as a potent antioxidant in humans, including in low-density lipoproteins (LDLs) where it protects them from oxidative damage.1,4,5 The coenzyme Q10 molecule can be found in all membranes throughout cells.6 It appears to works in conjunction with both vitamin E and vitamin C to provide antioxidant actions throughout the body.7

 

Coenzyme Q10 supports mitochondria to enhance cellular energy production*

 

Coenzyme Q10, with its widespread distribution throughout the body, plays a crucial role in mitochondrial physiology as a critical member of the electron transport chain. This transport chain, which is part of cellular respiration, leads to the formation of adenosine triphosphate (ATP), our body’s primary energy source.  Levels of this key nutrient may decline as a healthy person ages.7,8  Animal studies have found that supplementation can restore normal levels in certain tissues 6, and human studies suggest that supplementing with this enzyme may have increased benefits when a person has depleted levels. 7

 

Coenzyme Q10 supports healthy heart functioning*

 

Concentrations of coenzyme Q10 are understandably high in the heart as these muscle cells require high levels of energy to constantly function optimally. A number of studies (both animal and human) strongly suggest that coenzyme Q10 supplementation is supportive for healthy heart functioning and for maintaining cardiovascular system health.7,9

 

Ubiquinol has been studied for safety and bioavailability in humans*

 

A recently published single-blind placebo-controlled study in healthy subjects found no safety concerns in people who took Kaneka’s QH ubiquinol supplement orally at doses of up to 300 milligrams daily for up to four weeks.4 Single oral doses of either 150 milligrams or 300 milligrams were given to fifteen healthy men and women, and standard laboratory testing (including hematology, blood chemistry, and urinalysis) as well as physical examination and electrocariography (EKG) results showed no clinically significant changes when tested two days after supplementation as compared to before the taking the supplement. In addition to the single dose study, 80 healthy volunteers were given either placebo, 90, 150 or 300 milligrams of ubiquinol each day for four weeks, and again no clinically significant differences were seen in any of the testing parameters after two and four weeks of supplementation, nor were there differences two weeks after discontinuation of the supplement.  By monitoring levels in the blood, the authors found that ubiquinol was well absorbed.4

 

Studies in several animals also reveal no concern of toxicity in doses of ubiquinol up to 200 milligrams per kilogram of body weight for up to thirteen weeks.4 When compared to humans, this dose level is enormously higher than the recommended doses.  Supplementation with ubiquinol appeared to be safe at even higher levels (up to 600 milligrams per kilogram body weight) in a study using a different animal. In vitro assays additionally found no safety concerns for the use of ubiquinol, as it was found to be non-mutagenic and did not cause damage to chromosomes in cells.

 

Safety

Suggested Adult Use: Take one softgel daily with food, or as directed by a nutritionally informed physician.

 

Scientific References

1.    Mohr, D., V.W. Bowry, and R. Stocker, Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta, 1992. 1126(3): p. 247-54.

 

2.    Weber, C., et al., Effect of dietary coenzyme Q10 as an antioxidant in human plasma. Mol Aspects Med, 1994. 15 Suppl: p. s97-102.

 

3.    Okamoto, T., et al., Human serum ubiquinol-10 levels and relationship to serum lipids. Int J Vitam Nutr Res, 1989. 59(3): p. 288-92.

 

4.    Hosoe, K., et al., Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol, 2007. 47(1): p. 19-28.

 

5.    Stocker, R., V.W. Bowry, and B. Frei, Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proc Natl Acad Sci U S A, 1991. 88(5): p. 1646-50.

 

6.    Crane, F.L., Biochemical functions of Coenzyme Q10. Journal of the American College of Nutrition, 2001. 20(6): p. 591-598.

 

7.    Jones, K., et al., Coenzyme Q-10 and cardiovascular health. Alternative therapies, 2004. 10(1): p. 22-31.

 

8.    Schulz, C., et al., Comparison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10). Int J Food Sci Nutr, 2006. 57(7-8): p. 546-55.

 

9.    Coenzyme Q10. Monograph. Altern Med Rev, 2007. 12(2): p. 159-68.

 



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Active Coenzyme Q10
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Date: July 07, 2007 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Active Coenzyme Q10

Active CoQ10

 

The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.

In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. What is ubiquinol? Is it the same or different from CoQ10?

A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.

 

Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?

A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.

So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.

 

Q. What are the health benefits of CoQ10 and Ubiquinol?

A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.

In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.

 

Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?

A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.

 

Q. How might ubiquinol be important for the heart?

A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.S. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment. Since ubiquinol is the active form of CoQ10, it may be able to overcome the hurdles to providing maximum impact, most importantly, age and genetic related inefficiencies in converting CoQ10 to active CoQ10 (Ubiquinol).

 

And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.

The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.

Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.

The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.

Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.

 

Q. What have been the results of research studies with Ubiquinol?

A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.

Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Should I take CoQ10 or ubiquinol? How much should I take?

A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.

Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.

 

Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological diseases, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagines. The more we study this naturally occurring compound, the more benefits we find. And with this new ability to provide CoQ10 in its active form, ubiquinol, for the first time, even greater benefits may be derived.

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The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
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Date: May 18, 2007 01:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium

The Awesome Foursome: Coenzyme Q10, L-Carnitine,

D-Ribose, Magnesium

 

The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.

 

Coenzyme Q10:

Energy Recycling through the Electron Transport Chain

Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.

Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.

In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.

What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.

Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.

 

L-Carnitine:

Transporting the Cellular Energy Fuel

Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.

 

D-Ribose:

Rebuilding the Cellular Energy Pool

As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.

When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.

Ribose is the only compound used by the body to refill this energy pool.  Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency.  Ribose is made naturally in the cells from glucose.  In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis.  So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.

    Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy.  Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days.  But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose.  Conditions like ischemic heart disease or congestive heart failure fall into this category.  In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.

 

Magnesium:

Switching on the Energy Enzymes

Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism.  Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work.  Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.

    Magnesium deficiency reduces the activity of important enzymes used in energy metabolism.  Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function.  Small changes in magnesium levels can have a substantial effect on heart and blood vessel function.  While magnesium is found in most foods - particularly vegetables - deficiencies are increasing.  Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.

 

Supporting the Links in The Energy Cycle Chain – the Synergy

Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.

The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.

The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.

Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.

These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.

The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.

L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.



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CoQ10 for Heart Health
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Date: March 28, 2007 12:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10 for Heart Health

CoQ10 for Heart Health

 

More than 40% of all deaths in the U.S. are from cardiovascular disease (CVD). You have a greater chance of dying from heart disease than from cancer, AIDS, diabetes, and accidents combined. More than 2,600 Americans die each day of CVD – an average of 1 death every 33 seconds. One in 5 men and women have some form of CVD. If all forms of major CVD were eliminated, life expectancy would rise by almost 7 years.

One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. For what health conditions is CoQ10 used?

A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.

 

Q. Why is CoQ10 especially important to heart health?

A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.

 

Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.

 

Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.

In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.

 

Q. What studies support this fact?

A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

 

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

 

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.s. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment.

 

Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?

A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.

 

The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

 

Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.

 

Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?

A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.

 

While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?

A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:

 

1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.

 

2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.

 

3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at Massachusetts General Hospital and Harvard Medical School.

 

4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.

 

Q. How much CoQ10 should I take?

A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.

 

CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

 

Q. What are some other heart-friendly supplements?

A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.

 

Q. What supplements support healthy blood pressure and cholesterol?

A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.

 

Conclusion

CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.

The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.

Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.

 

 



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Regulating Blood Pressure Naturally
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Date: March 28, 2007 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Regulating Blood Pressure Naturally

Regulating Blood Pressure Naturally

 

High blood pressure (also known as hypertension) affects about 65 million Americans, or about 1 in 3 adults. There are many potential causes of hypertension, but not necessarily any symptoms. In fact, 30% of the people who have high blood pressure don’t even realize it.

In other words, just because you don’t have symptoms doesn’t mean you don’t have high blood pressure. That’s why it’s called “The Silent Killer.” And, make no mistake about it: high blood pressure is dangerous. It is the number one modifiable cause of stroke. Just lowering blood pressure reduces the chance of stroke by 35 to 40 percent. Other conditions, including heart attack and heart failure can be reduced from 25 to 50 percent, respectively.

In this issue of Ask the Doctor, we’re going to talk about high blood pressure and an exciting natural treatment for lowering blood pressure safely and effectively.

Of course, changing blood pressure numbers depends, in a large part, on the choices we make every day – how much we exercise, the foods we eat, and our lifestyle overall. But, for those times we need extra help, there is a new, scientifically-studied supplement to help us along our path to better health and lower blood pressure.

 

Blood pressure guidelines from the National Heart, Lung, and Blood Institute.

Category

Systolic (mm/Hg)

Diastolic (mm/Hg)

Result

Normal

Less than 120

And Less than 80

Excellent!

Prehypertension

120-139

Or 80-89

Make changes in eating and drinking habits, get more exercise and lose any extra pounds.

Hypertension

140 or higher

Or 90 or higher

You have high blood pressure. Talk to your healthcare professional on how to control it.

 

Q. What exactly is blood pressure?

A. Blood pressure is divided into two parts, systolic and diastolic. Systolic is the pressure of the heart beating. Diastolic is the pressure of the heart and vessels filling. When blood pressure numbers are written out, like “120/80,” 120 is the systolic pressure and 80 is the diastolic pressure. The unit of measurement for blood pressure is millimeters of mercury, written as “mm/Hg.”

 

Q. What is considered high blood pressure?

A. A person’s blood pressure can naturally vary throughout the day – even between heartbeats.

However, if the numbers are consistently high (over 120 systolic and 80 diastolic), after multiple visits to your healthcare practitioner, you may have either pre-hypertension or high blood pressure.

Young arteries and arteries that are kept young through healthy diet and exercise are typically more elastic and unclogged. Blood flows through them easily and without much effort. However, as we age, our arteries become more prone to plaque buildup (due to diets high in saturated fat and sedentary lifestyles) and don’t “flex” as well under pressure. The result is faster blood flow, all the time. Over the long term, it damages heart tissue, arteries, kidney and other major organs.

To get a better idea of high blood pressure, compare your arteries to a garden hose. When unblocked, a garden hose allows water to flow through it quickly and easily – without any real rush or stress. However, if you block the end of the hose with your thumb, closing it off even a little, water rushes out much more quickly.

For many years, high diastolic pressure was considered even more of a threat than high systolic pressure. That thinking has changed somewhat but high diastolic numbers could still mean organ damage in your body – especially for individuals under 50.

 

Q. What courses high blood pressure?

A. The reasons for hypertension aren’t always clear. However, there are lifestyle factors that contribute to high blood pressure that you can change:

 

Body type: Weight isn’t always a reliable indicator of whether or not you’ll have high blood pressure – but the type of weight is. Lean body mass – muscle – doesn’t increase blood pressure levels the way that fat can. However, fat body mass, especially fat around your middle, can contribute to high blood pressure.

 

Sedentary lifestyle: Too often, many of us sit down all day at work, and then sit down all night at home. Over time, this inactivity usually leads to weight gain, making the heart work harder to pump blood through the body. In a way, it almost seems contradictory, but inactivity usually leads to higher heart rates.

 

Sodium intake: Sometimes it’s hard to believe how much salt there is in processed foods. However, salt intake in itself is not necessarily bad. For people with a history of congestive heart failure, ischemia, and high blood pressure, sodium is definitely out. For those individuals, it leads to more water retention, which increases blood pressure. (Salt’s effect on water retention is one reason that so many sports drinks have fairly high sodium content – the sodium in the drink prevents your body from sweating out too much water.) But, for healthy individuals, moderate salt intake, especially a mixed mineral salt like sea salt or Celtic salt (good salt should never be white) is fine.

 

Low potassium intake: Unlike sodium, potassium is a mineral which most Americans get too little of. Potassium helps regulate the amount of sodium in our cells, expelling excess amounts through the kidneys. Low levels of this mineral can allow too much sodium to build up in the body.

 

Heavy alcohol intake: Having three or more alcoholic drinks a day (two or more for women) nearly doubles an individual’s chance of developing high blood pressure. Over time, heavy drinking puts a lot of stress on the organs, including the heart, liver, pancreas and brain.

 

Unhealthy eating: Eating a lot of processed or fatty foods contributes to high blood pressure. Adapting a diet that is rich in fruits and vegetables, whole grain products, fish, nuts and magnesium and potassium (like the Dietary Approaches to Stop Hypertension, known as the “DASH” diet) can bring it back down.

 

Smoking: If you smoke, stop. Smoking damages the heart and arteries – period. Nicotine constricts blood vessels, increases heart rate, and raises blood pressure. This in turn, increases hormone production and adrenaline levels, further stressing the body.

 

As if that weren’t bad enough, the carbon monoxide in cigarette smoke replaces the oxygen in the blood, making the heart work even harder to make up the difference. Since the effect of a single cigarette can last for an hour, smoking throughout the day leads to continuously revved-up blood pressure.

 

Some of these factors might sound like a lot to overcome. The important thing to remember is that all of these behaviors are changeable. If you have high blood pressure, modifying any of these can significantly lower blood pressure as part of an overall plan.

 

Q. What are the blood pressure numbers I should see?

A. Experts consider healthy blood pressure numbers to be 115/75 mm/Hg. The reason? They found that the risk of cardiovascular disease doubles at each increment of 20/10 mmHg over 115/75 mm/Hg. Even small jumps in blood pressure numbers increase the risk of stroke and heart attack.

 

Q. Okay, so other than diet, exercise and lifestyle changes are there other natural ways or supplements I can use to lower my blood pressure?

A. Yes, in fact, you hear about some of them in the news all the time – fish oil, CoQ10, and garlic. As effective as these symptoms are, they typically lower systolic pressure much more than diastolic pressure.

However, there is a blend of scientifically and clinically studied natural ingredients that lower high blood pressure separately, and work even better when they’re combined. This combination blend contains: dandelion leaf extract, lycopene, stevia extract, olive leaf extract and hawthorn extract.

Every one of these ingredients has been studied and recommended for years. But now, a scientific study on a supplement that combines them in one synergistic formula shows encouraging results for lowering systolic and diastolic blood pressure.

Let’s take a look at each:

Stevia leaf extract

Supports healthy blood pressure levels according to clinical studies.

Hawthorn extract

Supports the heart and balance sodium and fluid levels.

Olive leaf extract

Scientifically shown to support healthy blood pressure.

Dandelion leaf

Helps reduce fluid retention

Lycopene

Clinically shown to support arteries, circulation and heart health.

 

Stevia:

Stevia (Stevia rebaudiana) originated in South America, and is often used as a sweetener. Glycosides in stevia, particularly stevoside, give the plan its sweet flavor 0 anywhere from 100 to 200 times sweeter than sugar.

The leaf of stevia is considered the medicinal part of the plant. Research shows that extracts of the leaf relax arteries and help prevent the buildup of calcium on artery walls – keeping them healthy and reducing blood pressure.

In a long-term, randomized, placebo-controlled clinical study, stevia reduced systolic and diastolic blood pressure. On average, participants’ blood pressure reduced from baseline 150 mm/Hg to 140 mm/Hg systolic and 95 mm/Hg to 89 mm/Hg diastolic.

And, in another double-blind, placebo-controlled clinical study, stevia lowered blood pressure quite significantly – by an average of 14 millimeters of mercury in both systolic and diastolic readings. Those are impressive numbers!

Despite its role as a sweetener, stevia may have a side benefit to for those with hypertension – blood sugar regulation. Scientific studies show that extracts of stevia regulated blood sugar and reduced blood pressure.

A clinical study showed that stevia extract actually improved glucose tolerance by decreasing plasma glucose levels during the test and after overnight fasting in all participants. Regulating blood sugar is very important for those with high blood pressure. When blood sugar levels are high, blood vessels are inflamed. Many people with diabetes have high blood pressure as well. In a paired, cross-over clinical study, stevioside (one of the compounds in stevia) reduced glucose levels in individuals with type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. It shows great potential in treating type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. Its shows great potential in treating type 2 diabetes as well as hypertension.

 

Hawthorn extract:

Hawthorn (Crataegus spp. Oxycantha) has been used since ancient ties as a medicinal herb – even being mentioned by the Greek herbalist Dioscorides, in the first century AD. Traditionally, it has generally been used for support of the heart. Modern research points to bioflavonoid-like complexes in hawthorn leaf and flower that seem to be most responsible for its benefits on cardiac health, like blood vessel elasticity.

The bioflavonoids found in hawthorn include oligomeric procyanidins, vitexin, quercetin, and hyperoside. They have numerous benefits on the cardiovascular system. Hawthorn can improve coronary artery blood flow and the contractions of the heart muscle. Scientific studies show that the procyanidins in hawthorn are responsible for its ability to make the aorta and other blood vessels more flexible and relaxed, so that blood pumps more slowly and with less effort – sparing the cardiovascular system such a hard workout.

The procyanidins in hawthorn also have antioxidant properties – protecting against free radical cellular damage.

And, hawthorn may also inhibit angiotensin-converting enzyme. Angiotensin-converting enzyme is responsible for retaining sodium and water, and may have roots in our evolutionary development. It influences blood vessel contraction and dilation, sodium and water balance and heart cell development – just about everything that has to do with blood pressure. This may have developed as a way of dealing with periods of drought and stress. By narrowing the blood vessels, the body could guarantee an adequate supply of blood and focus on repairing tissue.

Unfortunately, that can lead to real problems these days. Since many of us live in an industrialized society, and frequently have pretty sedentary lifestyles, conserving sodium just makes the conditions for high blood pressure that much worse.

Like the other ingredients in this combination, hawthorn showed benefits on other body systems, too. In clinical and scientific studies, it not only lowered blood pressure, but also showed anti-anxiety properties and regulated blood sugar.

 

Olive leaf extract:

Olive leaf (Olea europaea) comes up again and again in scientific and clinical studies as having beneficial effects on hypertension. One of olive leaf’s most beneficial compounds is oleuropein – the same compound that makes olive oil so helpful in reducing blood pressure. Here again, we have to look at the traditional Mediterranean diet, which features voluminous use of olives and olive oil. Not surprisingly, blood pressure is generally much lower in Greek and Italian populations.

But it’s not just the diet – scientific studies showed that oleuropein lowered blood pressure by relaxing the blood vessels and prevented buildup of plaque in arteries. Plus, whether in olive leaf extract or in olive oil, oleuropein works as an antioxidant, too.

 

Dandelion leaf extract:

Dandelion (Taraxacum offinale) leaves provide a healthy supply of vitamins, much like spinach. In fact, although it has become the bane of North American gardeners and lawn owners, dandelion greens are a component of many gourmet salads.

Medicinally, dandelion has been used for centuries, dating back to ancient Greece. Leaves intended for medicinal use are harvested before flowering, to ensure the most nutrients.

They are a very rich source of vitamin A, and contain vitamin D, vitamin C, carious B vitamins, iron, silicon, magnesium, zinc and manganese, too. Dandelion leaves produce a diuretic effect in the body, similar to a prescription drug. Since one of dandelion leaf’s traditional uses was the treatment of water retention, it’s really not too surprising. Dandelion leaf is also rich in potassium – one of the vital minerals many Americans lack in their diet. So, even though it may act as a diuretic, it replaces more potassium than the body expels.

The diuretic effect of dandelion can relieve hypertension by drawing excess water and sodium from the body and releasing it through the kidneys as urine. Getting rid of extra water and sodium allows the blood vessels to relax – lowering blood pressure.

 

Lycopene:

If a nutrient can be called exciting, lycopene is it. Lycopene is found mostly in tomatoes and processed tomato products, like pasta and pizza sauce. Related to beta-carotene lycopene shows great antioxidant abilities among its many talents. In fact, it shows even greater free-radical scavenging properties than beta-carotene, its more famous cousin. Healthy intakes of lycopene can guard against a variety of chronic conditions, including lowering LDL (bad) cholesterol, lowering homocysteine levels and reducing blood platelet stickiness that can lead to clogged arteries. It’s even being studied for its protective effect against prostate cancer.

And, for proof, you don’t have to look too far to see the amazing effect lycopene intake can have on health. The Mediterranean diet provides an excellent example. Its high intakes of vegetables, (tomatoes, of course, playing a central role) fish, and whole grains improve cholesterol levels and lower blood pressure. The research on lycopene as a stand-alone nutrient has been compelling. A randomized clinical trial found that not having enough lycopene was associated with early thickening of the arteries.

So, it makes sense that other clinical trials, showed that higher intakes of lycopene frequently meant less thickening of arteries, and a reduced risk of heart attack. In one study, the risk of heart attack was 60% lower in individuals with the highest levels of lycopene. In a multicenter study, similar results were found – men with the highest levels of lycopene had a 48% lower risk of heart attack.

 

Q. What can I expect taking this herbal combination?

A. You should notice both systolic and diastolic numbers lowering in about two weeks. The scientific study showed that for pre-hypertensive and stage I, (early hypertensive individuals) this combination for ingredients lowers both systolic and diastolic blood pressure.

When you’re taking herbs to support your blood pressure, it’s important to keep it monitored so you have an accurate reading (and record) of your numbers. If you need to, you can pick up a home blood pressure monitoring device. These can retail for anywhere from $30 all the way up to $200, but buying one in the $30 to $50 range is a good idea and money well spent. Consider taking the machine to your local doctor’s office or fire department to have it tested for accuracy against a professional blood pressure monitor. See the chart below for tips on getting an accurate reading from a home monitor.

 

Tips for Accurate Blood Pressure Monitoring:

-Relax for about 5 to 10 minutes before measurement.

-If you have just come inside from cold outdoors allow yourself to warm up.

-Remove tight-fitting clothing and jewelry.

-Unless your physician recommends otherwise, use left arm to measure pressure.

-Sit, don’t stand.

-Remain still and do not talk while using the monitor.

 

Q. Are there any side effects?

A. There were no side effects noted in the study. However, because of the mild diuretic effect of dandelion leaf extract, you may notice an increase in trips to the bathroom. It’s always important to make sure you don’t get dehydrated, so you may want to drink more water during the day.

 

Conclusion:

High blood pressure doesn’t happen overnight. As we get older, the likelihood of developing hypertension increases. And, stressful, fast-forward lifestyles, bad diets and no exercise conspire to raise our blood pressure.

 

In my own practice I have helped patients move toward a healthier lifestyle, including diet, exercise, and blood-pressure reducing supplements. They live better, more vibrant lives as a result, and their blood pressure normalizes. It really can happen – you can bring your blood pressure back to normal, and this combination of scientifically and clinically validated ingredients can help.



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Neurological Health and CoQ10
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Date: February 25, 2007 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Neurological Health and CoQ10

Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.

Q. Isn’t CoQ10 a supplement for heart health?

A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.

Q. How does CoQ10 affect brain health?

A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.

The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.

The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.

Q. What is the blood-brain barrier and why is it important?

A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.

Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.

Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.

Q. If CoQ10 is made in the body, why take supplements?

A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.

Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.

Q. How does CoQ10 help people with Parkinson’s disease?

A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.

A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.

Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.

The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.

The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.

Q. What were the results of clinical research on Huntington’s Disease?

A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.

Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.

Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.

Q. What other diseases could benefit from CoQ10 supplementation?

A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.

In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.

ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.

Q. Can taking CoQ10 prevent neurodegenerative disease?

A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.

Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.

Q. How much CoQ10 should I take?

A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.

CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

Q. What should I look for in a CoQ10 supplement?

A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.

Conclusion

CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.

All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.



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For Better Heart Health ...
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Date: February 06, 2007 12:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: For Better Heart Health ...

Nutrients Every Heart Needs

 

High blood pressure. High cholesterol levels. Ever increasing stress. All are factors related to the development of heart disease – the leading cause of death for both men and women. In fact, 1 in 2 women in the United States die of heart disease or stroke, while 1 in 30 dies of breast cancer. If current trends remain unchanged, not only will heart disease remain the primary killer in our country, the number of people it claims will steadily and dramatically increase in the next 20 years.

 

Fortunately, heart disease is a problem you can do something about. Proven ways to prevent or mitigate the effects of heart disease include taking targeted nutritional supplements, making changes in the foods we eat, exercising most days of the week, drinking in moderation, eliminating tobacco use and adapting a positive attitude. Research shows that those of us who are often angry and depressed have more heart disease than people that live their lives with a more positive outlook.

 

In this Ask the Doctor, we’ll talk about specific nutritional supplements that are heart healthy, whether your goal is to prevent heart disease or reduce the effects of heart disease if you currently have it.

 

Q. I am trying hard to live a healthier life. But it all seems so overwhelming. How do I start?

A. It may help to know that you’re not alone in feeling overwhelmed. Lots of people feel this way. This is why the Centers for Disease Control and the American Heart Association are both urging people to prevent heart disease by identifying their individual health risk factors.

 

A risk factor is an indicator of whether or not you may develop a certain health condition. In heart disease prevention, there are two kinds of risk factors. There are risk factor you can control – such as diet, exercise, and the supplements you take. There are also risk factors you can’t change or control –your age, race, and gender, as well as your family’s history of heart disease.

 

Examples can be really helpful. Let’s follow three adults – Fred, Jane, and Earl – and determine their risk factors.

 

Low Risk

Fred is 32, single, has a job he loves, has an optimistic attitude about his life, and works out 5 days a week. Most days Fred’s diet is fruits, vegetables, whole grains and low fat. Occasionally Fred will eat a cheeseburger and fries when he watches the game with his buddies. Fred’s risk factors are his male gender and the occasional high fat content in his diet.

 

Moderate Risk

Jane is 55, a lawyer, married, and has a very stressful job. Jane eats lots of salads, fruits, and whole grains. However, her job requires her to work long hours which leaves little time to exercise. Jane is for the most part happy with her life, but her work stress had led to times of negativity. Her father had a heart attack when he was 56. Jane’s risk factors include her age (greater than 50), negativity from job stress, lack of regular exercise, and a family history of heart disease.

 

High Risk

Earl is 65, married, and has just retired from a job he hated. He spends most of his day watching TV and eating potato chips and other high fat, salty snacks. Earl has told his friends and family since he worked so hard for so long, he is sure to drop dead soon after retiring. He has high cholesterol and high blood pressure. Earl’s father had a heart attack and died when he was 73. Earl’s risk is his male gender, age (greater than 50), sedentary lifestyle, poor diet, negative outlook on life, high cholesterol and high blood pressure, and a family history of heart disease.

 

Q. OK, it’s pretty easy to see that Fred needs to watch his diet, Jane needs to exercise more, and Earl needs lots of help. But, which supplements should they take?

A. The Whole Heart Nutrition chart is an easy way to determine the supplements each risk level needs. As you can see, everyone wanting to prevent heart disease – Fred, Jane, Earl, you, and I – need to take quality heart formula multivitamin, garlic, and a fish oil supplement providing Omega-3 fatty acids. CoQ10 is also a smart choice for complete heart heath support.

 

Q. Why do we all need to take a “heart multivitamin”? Why can’t we take a regular multivitamin to prevent heart disease?

A. Since the human heart simply cannot function without adequate amounts of certain vitamins and minerals, it seems logical that a multivitamin would be the foundation of good nutrition for your heart. Heart-health formulated multivitamins provide the exact nutrients needed to prevent heart disease.

 

That’s why we need to take a specially formulated heart-focused multi-vitamin. The cells and the tissues that make up the heart must have vitamins C, A, and E, as well as B1, B6, and B12 to function. Folic acid, the little B vitamin that is so crucial in preventing spina bifida (a birth defect), breast cancer, and Alzheimer’s disease is also needed to keep heart muscles strong. The B vitamins and folic acid are very important to heart health because they help lower homocysteine levels. Homocysteine is a potential and emerging cardiac risk factor,

 

Magnesium is a mighty mineral and healthy hearts need it every day. Aloha lipoic acid, a fatty acid, provides protection against heart cholesterol and high blood pressure. Lutein and lycopene are all-natural nutrients and keep our arteries free from the buildup of plaque, a condition linked to heart attacks and strokes.

 

Multivitamins formulated with these exact vitamins, minerals, and nutrients will work with medications often prescribed to treat heart disease and provide the nutrition our hearts need.

 

Q. Don’t all multivitamins work with medications prescribed to treat heart disease?

A. Many multivitamin formulas contain herbs and other nutrients that can interfere with prescription medications, especially mediations prescribed to treat heart disease. One multivitamin does not fit all.

The more risk factors you have, the greater your chance of developing heart disease.

Factors you CAN’T change

 

Increasing age

About four out of five people who die of coronary heart disease are 65 or older.

Male gender

Men have more heart attacks than women. Even after menopause, when women’s death rate from heart disease increases, men continue to have more heart attacks until both groups reach their 80s.

Heredity (including Race)

While heart disease has often been noted to occur in families, recent research has shown this link may be the result of environment more than heredity. In other words, your dad’s high blood pressure and your high blood pressure may be related more to your mutual love of salty foods than your genetics. African Americans tend to have very high blood pressure and a higher risk of heart attacks than other races.

Factors you CAN change

 

Tobacco smoke

Smokers have twice the risk of heart attack than nonsmokers.

High blood cholesterol

As blood cholesterol rises, so does the risk of heart disease.

High blood pressure

High blood pressure increases the heart’s workload, causing the heart to thicken and become stiffer.

Physical inactivity

Exercise most days of the week helps prevent heart disease. The more vigorous the activity, the greater your benefits.

Obesity and overweight

People who have excess body fat are more likely to develop heart disease and stroke even if they have no other risk factors.

Individual coping styles

Research has shown there is al ink between heart disease risk and stress, happiness, negativity, and socioeconomic status.

Alcohol consumption

Drinking too much alcohol can raise blood pressure. However, the risk of heart disease in people who drink moderate amounts of alcohol (an average of one drink for women or two drinks for men per day) is lower than in nondrinkers.

 

Q. What can garlic supplements do for Fred, Jane and Earl or other people with low to high risk factors?

A. Garlic supplements have a very long and very successful history of preventing premature death from heart attacks. Lately, however, there have been some conflicting news stories about supplemental garlic’s ability to lower high cholesterol and high blood pressure – the causes of heart disease and death. That’s because many different garlic supplements have been used in these studies – garlic oil, garlic powder, aged garlic extract, and supplements made from fresh garlic. They have all been studied clinically for their effects in heart disease.

 

The best garlic supplements (and the ones that showed the best effects in garlic studies) contain alliin, which is then converted to allicin. Allicin is the compound that lowers harmfully high cholesterol levels and dangerous blood pressure readings. Allicin is also responsible for garlic’s characteristic odor. Because alliin is very stable when dry, properly prepared and enteric coated fresh garlic preparations preserve the allicin-producing action until the garlic mixes with the fluids of the intestinal tract. Fresh garlic extract’s enteric coating also prevents garlic breath. In contrast, aged garlic contains absolutely no allicin or allicin potential. This fact is probably responsible for the poor results noted in lowering cholesterol and blood pressure from aged garlic preparations.

 

The most effective garlic supplements are made from fresh garlic, enteric coated, and provide a daily dose of at least 10 milligrams (mg) alliin or a total allicin potential of 4,000 micrograms (mcg). Taking a once-daily garlic supplement that delivers 4,000 mcg of allicin will lower Jane’s and Earl’s high blood pressure and Earl’s high cholesterol, naturally and effectively.

 

Whole Heart Nutrition

Supplement

Low Risk

Moderate Risk

High Risk

Heart multivitamin

Every day

Every day

Every day

Garlic supplement 4,000 mcg allicin

1 tablet each day

1 tablet each day

1 tablet each day

Fish oil supplement with omega-3 fatty acids

600 mg each day

1200 mg each day

1800 mg each day

CoQ10

60 mg

100-200 mg each day

200-400 mg each day

Each additional risk factor requires additional supplements or increased doses for protection from heart disease.

 

Q. What about fish oil supplements? I know they can prevent heart disease but I’ve also heard they contain harmful substances, too.

A. You’re right on both counts. But, there are excellent fish oil supplements naturally loaded with Omega-3 fatty acids, powerful nutrients that prevent heart disease, that are also certified free of harmful contaminants.

 

In the 1980s, researchers first began noticing the native Inuit (Eskimo) populations of Greenland and Alaska had hardly and heart disease despite a very high-fat diet. The deep-water fish that these peoples eat (and continue to eat to this day) are indeed quite fatty. But, this kind of fat, rich in Omega-3 fatty acids actually protects the heart instead of harming it.

 

Research has shown that the Omega-3 fatty acids in fish oil supplements can:

-Reduce the risk of arrhythmias, lethal heartbeat rhythms that cause sudden death.

-Lower the levels of triglycerides, fats in the blood that can increase a person’s

risk of dying from a heart attack, even if a person’s cholesterol levels are normal.

-Slow atherosclerosis – the growth of harmful plaque on artery walls.

Atherosclerosis develops over many years. If the plaque growth is slow and

stable, chances are low that a heart attack will result. However, rapidly growing

or unstable plaques can rupture. The body responds with inflammation, which

causes blood clots to form. These blood clots block the artery and cause a heart

attack.

-Keep blood pressure levels low. Many people have high blood pressure for years

without knowing it. That’s because it has no symptoms. Uncontrolled high

blood pressure can lead to stroke, heart attack, heart failure, and kidney failure.

While 25% of Americans have high blood pressure, nearly one-third of these

people don’t know they have it. This is why high blood pressure is often called

the “silent killer.”

 

You can get all of this heart disease preventive protection from just 600-1800 mg of fish oil. It’s pretty simple to see why Fred, Jane, Earl, and you and I need to take fish oil supplements every day.

 

However, it is absolutely critical that the fish oil supplement you take is free of contaminants and guaranteed fresh! Make sure that the manufacturer of the fish oil supplement you buy is able to provide documentation of purity in their product. Supplements should contain no detectable dioxin (a widely used toxic preservative), DDT (a toxic insecticide), PCBs (polychlorinated biphenyls) or heavy metals such as mercury and lead.

 

Before you buy any fish oil supplement, ask the clerk if you can open the bottle or jar and smell the contents. A fishy smelling fish oil supplementation means it is rancid. Rancid fish oil is not going to help your heart at all and may actually hurt it.

 

Q. That leaves CoQ10. Why is it important for Jane and Earl?

A. CoQ10, also known as ubiquinone, is the premier heart supplement! CoQ10 is part of our energy producing system. It works directly in the mitochondria of each cell. Mitochondria are highly specialized structures within each cell and are often referred to as powerhouses. These tiny energy producers generate 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. The heart has very important functions and requires a vast amount of energy. Thus, the heart has a lot of mitochondria or little powerhouses.

 

CoQ10 is incredibly crucial to the health of our hearts. Especially to hearts that are pumping blood with too much cholesterol. But, in a dangerous paradox, CoQ10 levels can become dangerously depleted when physicians treat high cholesterol in their patients with certain medications. The so-called “statin” drugs (Mevacor/lovastatin and Crestor/rosubastatin are two examples) are powerful and medications prescribed to lower harmful cholesterol levels. However, one very harmful side effect they share is that they deprive cells of CoQ10. While some physicians are aware of this serious side effect and tell their patients to take at least 400 mg of CoQ10 each day, most are not. The result? Any good the statin drugs may be doing is actually negated by their depletion of CoQ10.

 

Q. How does CoQ10 actually work? Has it been studied in heart disease?

A. Yes, it has! CoQ10 has been extensively studied in heart disease. This natural nutrient is present in every nucleated cell in our body (the only cells that don’t contain CoQ10 are red blood cells). Heart cells, however, are absolutely loaded with CoQ10. Its job is fairly simply – CoQ10 is vital to the production of adenosine triphosphate (ATP), the compound our body uses for 95% of its energy needs.

 

In 1998, 144 patients who had been admitted to the hospital after a heart attack, participated in a CoQ10 study. Half of the patients received 120 mg of CoQ10 a day in addition to the usual treatments given to heart attack patients. The other half, the control group, received the usual treatments and a placebo, but no CoQ10.

 

The results showed that the group taking CoQ10 had less irregular heartbeat, experienced less angina (a type of heart pain), and had much better function in the left ventricle (the most essential chamber of the heart), compared to the placebo group. Total deaths due to sudden heart failure or another heart attack were also reduced in the CoQ10 group.

 

Q. What if I have already been diagnosed with Congestive Heart Failure? Will CoQ10 still help me?

A. CoQ10 has been proven in study after study to help slow down the destruction that occurs in congestive heart failure (CHF), a serious heart disease, and heal the heart muscles damaged by heart attacks. In fact, heart attacks often occur when the body’s CoQ10 levels are low.

 

In a CHF study, patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the researchers introduced a catheter into the right ventricle of the patients’ hearts to determine the degree of muscle damage CHF had caused. In the group who took CoQ10, the pumping ability of the heart improved significantly. The placebo group’s hearts did not. The researchers conducting the study recommended that people with CHF add CoQ10 to the other medications they need to take to stay alive and well.

 

Q. Are some types of CoQ10 better than others?

A. Indeed they are. CoQ10 products are not created equally. The key to this natural medicine is the quality of the manufacturing. Take a CoQ10 supplement that’s been used in research conducted by prestigious universities (it will tell you this right on the label). Researchers want the best CoQ10 for their studies. You want the best CoQ10 for yourself and your loved ones.

 

The best CoQ10 has to meet the following criteria:

1. Must be easily absorbed during the digestion process so that it can get into the

bloodstream.

2. Must reach the mitochondria in the cell.

3. Must be proven effective in studies.

4. Must be safe and free of impurities.

 

Q. It sounds as if CoQ10 is only for people with moderate or high risk factors. Can others benefit from this supplement?

A. Many people, including those like Fred with low risk factors or no risk of heart disease take CoQ10 every day. CoQ10 supplements may reduce your risk of cancer, prevent gum disease, and help certain nerve cells work more effectively.

 

Conclusion

Understanding your personal risk factors, making it better lifestyle choices, taking a multivitamin formulated for your heart, an enteric-coated fresh garlic supplement, fish oil supplement with Omega-3 fatty acids, and CoQ10 – the heart’s super-nutrient – can help keep your heart healthy and strong.

 

Helen Keller, the famous lecturer and author, who was both blind and deaf wrote, “The best and most beautiful things in the world cannot e seen or even touched. They must be felt with the human heart.”

 

Healthy hearts have the most opportunities to “feel” the best and are the most beautiful thing our world has to offer.

 



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Lower Cholesterol Naturally!
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Date: October 06, 2006 09:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lower Cholesterol Naturally!

Because of organizations like the American Heart Association (AHA), we’ve learned a lot about cholesterol and how it affects our health. Thanks to these educational organizations, we know that high cholesterol levels can increase our risk for heart attacks and strokes and, by lowering these levels, we reduce these risks as well as keep our hearts and blood vessels healthy. We also know that our cholesterol levels can be improved through exercise, diet, and weight loss.

Although we’ve learned a lot through these educational organizations, there are still a few misconceptions about cholesterol. One of these being that not all cholesterol is harmful. There are both “good” and “bad” forms of cholesterol and a good balance between the two is what is needed for a healthy heart. Because so much emphasis is placed on lowering “bad” cholesterol levels, not enough attention is paid to the benefit of raising “good” cholesterol levels (HDL). Research states that raising HDL levels can provide even greater protection against cardiovascular disease than just simply lowering “bad” cholesterol levels. By raising HDL levels by simply 1%, the risk of heart disease can be lowered by 2% in men and 3% in women. Many studies have shown that low HDL cholesterol levels are an independent risk factor in heart disease. This is extremely important because we’ve learned that despite efforts to change a person’s diet and exercise habits, some people’s cholesterol levels are still unhealthy.

Prescription drugs to lower cholesterol are now available and have been proven by multiple studies to be very successful. The statins’ effectiveness in reducing LDL (“bad”) cholesterol has produced highly significant reductions in heart attacks and strokes. Although these medications do lower cholesterol levels, their side effects must be considered. Statin drugs can cause liver irritation, reduce CoQ10 levels in the body, are associated with myopathy, and are even linked to a rare and sometimes fatal condition called rhabdomyolysis. These drugs also have a relatively small effect on good (HDL) cholesterol levels. Thankfully, there are safe and effective solutions available that can help you manage your cholesterol levels naturally. However, first we must review what we know about cholesterol and heart disease.

Cholesterol is a fat-like substance needed to help digest fats, strengthen cell membranes, make hormones and insulate nerves. Although it is found in every cell of the body, cholesterol is mainly made in the liver, as well as cells lining the small intestine. Even though our bodies make all the cholesterol we need, we also get cholesterol from the foods we eat, such as egg yolks and organ meats. All foods from animal sources contain cholesterol, while plant derived food, including peanut butter and avocado, contains no cholesterol at all.

Cholesterol is important to many functions of the body. However, too much cholesterol in the bloodstream is extremely dangerous. After blood cholesterol reaches high levels, it builds up on the artery walls, and thus increasing the risk for blood clots, heart attack, and stroke. If the cholesterol clogs any of the coronary arteries, the heart’s supply of oxygen and nutrients will diminish, resulting in coronary heart disease, angina, or even heart attack.

Because cholesterol and other fats can’t dissolve in the blood and thereby can’t travel on their own, they have to be transported to and from the cells by lipoproteins. The two major lipoproteins are low density lipoproteins (LDL or “bad cholesterol) and high density lipoproteins (HDL or “good cholesterol”) LDLs carry cholesterol throughout the body to the cells and cause artherosclerosis by clogging up our arteries with fat. On the other hand, HDL prevents the fat buildup by carrying it away from the arteries and to the liver where it can be eliminated. Although high levels of LDL are associated with cardiovascular disease, high HDL can drastically reduce your risk of heart disease. As a result, the AHA has established three guidelines to keep your heart healthy: HDL levels about 40 for men and above 50 for women, LDL levels between 100 and 159, and a total cholesterol (HDL and LDL) of under 200.

Triglycerides are fats used as fuel by the body and a source for metabolism. These levels can fluctuate easily but increased levels are almost always a sign of too much carbohydrate and sugar intake. High amounts of triglycerides make the blood less capable of transporting oxygen and are another factor for cardiovascular disease. Thankfully, the HDL and LDL blend mentioned earlier can safely and effectively lower triglyceride levels.

It has been shown that high levels of HDL cholesterol are inversely related to coronary artery disease risk. However, what people do not know is that there are different subtypes of HDl, including HDL-2 and HDL-3. HDL-3 is produced by the liver and intestines and is responsible for scooping up free cholesterol from the blood vessel walls. The cholesterol carried by HDL-3 is chemically modified, forming a larger-sized subtype, known as HDL-2, or “mature HDL.” HDL-2 transports cholesterol to the liver for processing and elimination, and its molecules are then recirculated in the blood stream. Research has shown that HDL-2 provides more heart-protection because it moves the cholesterol away from arterial walls, and holds a greater number of receptor sites which allows it to carry a larger amount of cholesterol to the liver.

Although many prescription medications have been developed to lower bad cholesterol, there are very few medications that target good cholesterol. Therefore, patients with naturally low HDL cholesterol, who can not alter these levels through diet and exercise, have limited medical options to reduce their risk of heart disease. Multiple nutrients have been clinically shown to favorably alter good cholesterol levels including: vitamins C, E, B6, B12, niacin, folic acid, magnesium and selenium, with protein-building amino acids, powerful antioxidants such as coenzyme Q10, alpha lipoic acid, N-acetyle cysteine, and policosanol, and extracts of hawthorn, garlic, grape seed, and soy isoflavones. Although this HDL-boosting combination does not result in a significant reduction in LDL, antioxidants found in this formulation can help stabilize LDL and prevent build up in the arterial wall.

This formula combines essential vitamins and minerals, at levels recommended by the American Heart Association. It contains amino acids, antioxidants, and botanicals that have all been used safely for years. No serious adverse effects have been found following supplementation and the combination is safe to use with statin drugs.

Plant sterols, found in nuts, vegetable oils, corn, and rice are structurally similar to cholesterol and are able to block its absorption. Each day the liver receives about 800 mg of cholesterol from intestinal absorption through receptor sites. After entering these channels, the cholesterol is absorbed into the bloodstream. Since plant sterols look similar to cholesterol, they fit perfectly into these receptor sites and block the absorption, which allows the cholesterol to remain in our intestines where it can eventually be excreted. A large amount of plant sterols reduces the amount of cholesterol transported from the intestinal tract to the liver. This cholesterol reduction causes a decrease in LDL levels.

Even if a person does not have high cholesterol levels, reducing bad and raising good cholesterol greatly reduces their risk for ever developing chronic heart disease. Due to side effects, physicians do not normally prescribe statin drugs to people without actual heart disease of high LDL cholesterol levels. Instead, they recommend dietary changes. The HDL-boosting combination and LDL-lowering pantethine and plant sterols blend can effectively help people with heart disease, uncontrolled cholesterol levels, high triglyceride levels, or people who just want to improve their heart health.



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What are you really Getting?
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Date: August 21, 2006 05:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are you really Getting?

 

Supplement labels can be confusing!

 

The list of ingredients on some supplement labels can tax the mind of even a Ph.D. in nutrition!  What’s worse, although labeling laws exist to counter misleading and non-uniform labeling, confusing and deceptive labeling, confusing and deceptive labeling practices continue to abound.  Here’s some help to aid you in making better sense of supplement labels.

 

1.Begin at the Bottom

 

The supplement facts panel on the label of every nutitional supplement sold in the U.S. tells you about active ingredients in a product. Before analyzing this information, look beneath the panel, where the OTHER INGREDIENTS are listed.  Here, at a glance you can begin to spot a questionable product.  Synthetic colors, flavors, preservatives, or the absence of certain information, are early warning signals. 

 

Poor Label

 

 

Good Label

1.other ingredients: Cellulose, stearic acid, sucrose, sodium, silicoaluminate, talc, titanium dioxide, mineral oil, FD&C red #40, FD&C yellow, aluminum lake, polysorbate 80.

  1. other ingredients: Cellulose(capsule), vegetable magnesium state, silica.
  2. this product contains no gluten, wheat, yeast, eggs or dairy, no synthetic colors or flavors , and no toxic levels of lead or other heavy metals.
  3. Lot# 123456

Expires: 01/08 or use by: 01/08

 

 

  1. Other Ingredients: supplements can be natural only by degree, since their manufacture often requires the use of binders, flowing agents and other items.  Such materials may come from natural and artificial sources. They must be listed in descending order by quantity.
  2. Contains No / May Contain:  Sometimes, supplements are derived from sources that could cause reactions in allergic individuals (eg. Soy, shellfish).  Better labels tell you which allergens are absent, as well as those which may be present.
  3. Expiration date & lot Number: shelf life varies fro different supplements, but most will diminish in potency and quality over time.  Better labels provide a USE BYE or EXPIRATION date.  They also note a LOT NUMBER for identifying product origin (for tracking any product related problems).

 

2.Directions, Dose & Value

 

Poor Label

 

Good Label

 

DIRECTIONS: Take 6 tablents daily, two with each meal.

 

Directions: Though not required on labels, directions tell how and when to take supplements.  This is important because timing your doses can affect absorption. In general:

 

·        Vitamins are best absorbed when taken with food, and in divided doses throughout the day.

·        Fat-soluble vitamins (A,D,E,K) require dietary fat for absorption, so are best taken with meals.

·        Many minerals can be absorbed effectively at any time.

·        Most herbs, probiotics, amino acids & proteolytic enzymes (not digestive enzymes, which should be taken with meals) are best taken on an empty stomach.

 

Poor Label

Good Label

Supplement facts

    1. serving size 3 tablets
    2. servings per container 20
    3. % DV (Daily Value)

Supplement facts

1. Serving Size 2 Tablets

2. Servings per container 30

3. % DV (Daily Value)

 

1. Serving size: SERVING SIZE is required on labels. It recommends the number of tablets, capsules, spoonfuls, ect. Taken at one time.  Be ware that a serving is not necessarily the total recommended daily amount.

 

2.      Cost-Effectiveness: To determine, first find the SERVING SIZE.  Then read the directions to see how much servings are suggested daily.  Finally, divide the number of servings needed into the number of SERVINGS PER CONTAINER.

 

Example: Assuming the two bottles above have the same ingredients and cost. The product on right offers more servings, and is a better buy. Product on left just has less nutritive ingredients, or more filler, in each pill.

 

3.      % DV (Daily Value): The daily value of a nutrient represents the amount expected to meet the daily needs of an “average” healthy person.  On labels, % DV indicates provided by one serving.  DVs have not been established for herbs, essential fatty acids and other nutrients.

 

Note: Many experts in nutrition think that suggested DV levels for some nutrients are far too low to optimize health.  This is why certain ingredients may be present at greater than 100% DV levels.

 

3.Games Labels Play

 

There is no free lunch in the world of supplements.  A bottle that costs less probably contains less – either fewer nutrients, or less effective forms of nutrients.  Educate yourself; compare ingredient amounts, forms and sources, and watch out for labeling tricks such as these.

 

“Padding” the label

 

padding” the label is a common way for supplement marketers to make their ingredients list look more complete and beneficial than it really is.  Padding methods include:

 

Poor Label  amount per serv.

Good Label  amount per serv.

1.CoQ10……….1000mcg

2.Oat Bran………20mg

   Oat fiber……….1mg

3. Oat flavonoids…25mcg

1. CoQ10………….50mg

 

  1. Pixie Dust:  Adding useful ingredients in therapeutically useless amounts. Some brands use tiny amounts of nutrients just to get the ingredient on the label.  Learn how much nutrient is required, and be watchful of inappropriate measurement sizes. (See Weights & Measures below.)

 

Example: CoQ10 useful range is 30mg to 400mg (milligrams.)  product on left provides 1000mcg  (microgram) of CoQ10, the equivalent of just one mg!  product on right provides a beneficial 50mg.

 

  1. Sounds Good:  Adding impressive but irrelevant ingredients, often in useless amounts, that are of no benefit to the formula.

Example: Whole grains such as oats are part of a heart healthy diet, but the product on left provides less than a pinch 20mg of oat bran.  Product on right includes no irrelevant ingredients in useless amounts.

 

  1. Expanding Assets:  Separately listing the parts of a single ingredient to give the illusion of additional ingredients. 

Example: Fiber and flavonoids are part of oats, not more ingredients.

 

The “Name’s the Same” Game

 

A common trick is to provide unproven, weak or useless forms of familiar, good ingredients.  Buyer beware!

 

Poor Label  .

Good Label   .

Pygeum Bark Powder

Pygeum Africanum…..100mg

Pygeum Bark Extract

Pygeum Africanum (Standardized to 13% total sterols……….100mg

 

Example: Studies suggest that Pygeum bark standardized extract helps support prostate health.  Product on left uses unresearched powdered bark.

 

 

Proprietary Blend = “It’s a Secret”

 

Some companies may hide the quantity and quality of their ingredients by calling their formula  a “Proprietary Blend.”  This term may allow manufacturers to use a lot of nutrient from a cheap source and very little from a good source without disclosing how much of each you are actually getting. 

 

This deceptive practice is legal—as long as the secret blend:

·        Is labeled “Proprietary Blend” (or fanciful trademark name)

·        Lists individual nutrients in descending order by weight

·        Lists the total weight per serving

 

When you see the word “Proprietary,” ask: “how relevant is the first or second ingredient?”  Sometimes, the most abundant ingredients are either fillers, or inexpensive, less effective forms.

 

Poor Label              amount per serv.

 

Good Label             amount per serv.

Special Proprietary Women’s Blend

Alfalfa herb, Black Cohosh root, Chaste Tree berry, Dong Quai root, Licorice root………….350mg

Black Cohosh root

Cimicifuga Racemonsa (2.5% total triterpene glycosides)…….125mg

Chast Tree berry

Vitex agnus-castus (0.5% agnusides)………………..100mg

Dong Quai root

Angelica sinensis (5:1 extract)..75mg

Licorice root

Glycyrrhiza glabra……………50mg

Example: Legally, product on left could contain 99% alfalfa filler and only 1% of all the other herbs together! The Good Label tells all.

 

Hiding Outside the Box

 

Another clever way to hide the quality of ingredients is by listing them outside the Supplement Facts box, in the Other Ingredients section located beneath the box.  This section is usually intended for listing agents used in the tableting or encapsulation process.

 

 

Poor Label

 

Good Label

Other Ingredients: Cellulose, stearic acid, spirulina, lycopene, grape seeds.

Other Ingredients: Cellulose, vegetable magnesium stearate.

Example: Agents used in supplement manufacture (i.e. cellulose and stearates) should be listed under Other Ingredients.  Product on left also uses this section to list catchy sounding spirulina, lycopene, and grape seeds.  With no amounts listed, assume these ingredients are present in low levels that provide little value.  A supplement maker who is proud of a product’s nutritive ingredients will fully disclose amounts within the Supplement Facts box not list these ingredients along with manufacturing agents in the Other Ingredient section.

 

4.Understanding Herbs

 

 

Herb Forms: Powders, Tinctures, Extracts

 

The form, preparation and concentration of an herb affects its potency and influences the herb’s potential for therapeutic effectiveness.  the potency of all herb forms except standardized extracts are uncertain and depends on factors invisible to the consumer (i.e. soil quality, rainfall, seasonal climate, harvesting methods, storage methods and age).

 

            Know Your Plant Parts: Medicinal plants often have specific parts that are most effective therapeutically, such as the root for goldenseal, the leaf for raspberry, and the blossom for clover.  Products using irrelevant plant parts may cost less, but offer little or no benefit!

 

Powdered Herb

 

Often encapsulated or used as tea, powdered herbs are more likely than other forms to lose potency when exposed to air.  Fresh, high quality powdered herb may add therapeutic or nutritional value to a supplement.  Low quality powders may provide little benefit.  Look for expiration or “use by” dates.

 

Poor Label

 

Good Label

Saw Palmetto………..320mg

Saw Palmetto berry

Serenoa repens……320mg

Example: If the label doesn’t say otherwise, assume the form of herb is powdered.  Better labels specify plant part and latin name (genus and species).  Sometimes a less effective species of a plant is used to save money.  Check to see if other related species may be equally effective.

 

Tinctures and Fluid Extracts

 

Tinctures contain the soluble parts of dried or fresh herbs, often extracted in a mixture of alcohol and water, vinegar or glycerin.  Tinctures are usually dispensed by drops. This form is more stable and thus has longer shelf life than powdered herb.

 

Poor Label

 

Good Label

Saw Palmetto berry

Tincture…………..320mg

Saw Palmetto berry

Serenoa repens 1:5 tincture, 40% alcohol………………..320mg

Example: Better labels specify tincture strength as a ratio.  Regular tinctures are made using 1 or 2 parts herb to 10 parts solvent, yielding strength ratio of 1:10 or 1:5.  higher potency tinctures (also known as fluid extracts) use more herb in less solvent, yielding stronger 1:3, 1:2, or even high strength 1:1 ratios.

 

Concentrated and standardized extracts

 

Concentrated or standardized extracts (solid, powdered, liquid) are generally prepared from evaporated herbal tinctures or teas.

 

Poor Label

 

Good Label

  1. Saw Palmetto Berry Extract..……..320mg
  2. Saw Palmetto berry standardized extract………..320mg
  1. Saw Palmetto berry

Serenoa repens extract 5:1…………320mg

  1. Saw Palmetto berry

Serenoa repens (standardized to 85%-95% fatty acids and sterals)………320mg

 

  1. Concentrated extracts commonly use 4 to 8 parts of plant matter to make 1 part extract (4:1 to 8:1).  Some may use up to 200 pounds of herb to make 1 pound of finished product (200:1)!

Example: A better label tells you the concentration strength by noting the ratio of herb to extract.  This is often appears after the plant name.

 

  1. Standardized Extracts are lab-analyzed to provide a verified amount of one or more nutritive ingredients.  In many cases, proportional amounts of other constituents are also present, retaining the natural “fingerprint” of the whole herb.  Standardized extracts are the most consistent, and often the most potent, form of an herb.  They are used in the majority of studies demonstrating therapeutic effectiveness.

Example: Standardized extracts provide a set percentage of an herb’s researched nutritive ingredient.  Useless this percentage is noted on the label, the term “Standardized” is meaningless.

 

5.Beware of False Claims

 

Is it science of is it marketing?  To avoid being misled, question all claims on supplement labels as well as in advertisements.  Although government guidelines restrict the types of claims that manufacturers can legally use to promote their products, not all companies comply.  Many promises mount to little more than marketing hype.

 

Use common sense to decide if a claim seems realistic.  Be aware of emotionally charged, misleading language in advertising.

 

When doubt, contact the company and request information to support a claim.  Unbiased research and human studies are most relevant.  If the science seems legitimate, verify that the form and dose used in product match form and dose showing benefit in studies.

 

Weights & Measures

1 kilogram (kg) = 1000grams (g)

1 gram (gm) = 1000 milligrams (mg)

1 milligram (mg) = 1000 micrograms (mcg)

1 liter = 1000 milliliters (ml)

946 milliliters (ml) = 1 quart

30 ml = 1 fluid once

1 teaspoon, medical = 5 milliliters (ml)

1 tablespoon = 15ml = ½ fluid ounce

28.35 grams (gm) = 1ounce

1 kilogram = 2.2 pounds

Vitamin E

Measured in mg alpha-tocopherol equivalents 1 mg alpha tocopherol = 1.49 IU

Beta Carotene 1mg = 1667 IU

Vitamin A

1 RE (retinol equivalent) = 5 IU

1 RE = 6mcg of beta carotene

1 RE = 1mcg of retinol

Vitamin D

Measured in mcg cholecalciferol

1 mcg cholecalciferol = 40 IU

 

 

 



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HDL Booster - Boost your good cholesterol
TopPreviousNext

Date: March 16, 2006 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL Booster - Boost your good cholesterol

 

                                      

 

 

HDL BOOSTER

(Product No. 02922)

 

 

 

DESCRIPTION:

 

HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*  

 

HDL Booster:

 

·         Formulated by Dr. Dennis Goodman, Chief of Cardiology at Scripps Memorial Hospital

·         Clinically studied to increase good cholesterol levels up to 23%*1

·         All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association

·         Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2

 

STRUCTURE/FUNCTION:

 

HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*  

 

FORMULA:

 

Two tablets (one serving) contain:

 

Vitamin C (ascorbic acid)                                                          148 mg

Vitamin E (as natural mixed tocopherols)                                    35 IU

Niacin (as niacinamide)                                                              21 mg

Vitamin B6 (as pyridoxine HCl)                                                  3 mg

Folic Acid                                                                                 301 mcg

Vitamin B12 (as cyanocobalamin)                                              20 mcg

Magnesium (from magnesium amino acid chelate)                       10 mg

Selenium (as L-selenomethionine)                                               49 mcg

Proprietary Blend                                                                      388 mg

   hawthorn (Crategus oxyacantha) berry extract,         

   taurine, garlic (Allium sativum) bulb, grape seed (Vitis

   vinifera) extract, grape skin (Vitis vinifera) extract,

   N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine

   max) isoflavones, tocotrienols

L-Arginine (as L-arginine HCl)                                                  153 mg

L-Carnitine (as L-carnitine L-tartrate)                                        51 mg

Coenzyme Q10 (CoQ10)(ubiquinone 10)                         25 mg

Policosanol                                                                                7 mg

 

Other ingredients: See label for most current information.

 

Contains no: sugar, salt, yeast, wheat, gluten,  corn, dairy products, artificial coloring, artificial flavoring, or preservatives.  This product contains natural ingredients; color variations are normal. 

 

INTRODUCTION:

 

Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5

 

Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4

 

Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4

 

Types of Cholesterol

 

Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5

 

LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6

 

Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7

 

The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7  

 

HOW IT WORKS:

 

HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9

 

Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at Scripps Memorial Hospital to evaluate the effects of a proprietary supplement on lipid profiles. The dietary supplement, which mirrors HDL Booster and contains a combination of antioxidants, B-vitamins, amino acids, and botanical extracts, was developed by Dr. Goodman, the leading cardiologist at Scripps. The trial involved 50 people, who were evaluated prior to the study, then again at three and six months. After three months of supplementation, good cholesterol levels increased in all groups.* The changes were more pronounced at the six-month time point, where good cholesterol rose up to 23 percent and levels of HDL-2 (the best cholesterol) increased 50 percent in one subset of participants (HDL <40 mg/dL).*1 Additionally, the supplement also helped maintain healthy triglycerides levels that were already within the normal ranges.* Decreases in homocysteine, an amino acid found in the blood that plays a role in cardiovascular health, were observed as well.*1,10

 

The following chart summarizes the benefits of each of the ingredients in HDL Booster:

 

Ingredient

Benefit

Vitamin C

An antioxidant clinically shown to support the health of the cardiovascular system and increase HDL-2 cholesterol levels.*11,12 An important factor in many metabolic reactions, including the conversion of cholesterol to bile salts and the formation of healthy connective tissue. Vitamin C provides protection for the inner lining of the arteries.*13,14

Vitamin E

Another powerful antioxidant, which inhibits the oxidation of low density lipids by inactivating free radicals.* Thought to inhibit the breakdown of certain fatty acids that help form cell structures, especially membranes13

Also supports healthy cholesterol levels already within the normal range.*15,16

Niacin

In lipid metabolism, supports normal cholesterol production and metabolism to help retain healthy cholesterol levels that are already within normal limits.*13 Increases good cholesterol levels, particularly HDL-2 (the best cholesterol).*17 Through peripheral vasodilatation, niacin also supports the retention of healthy blood pressure that is already within the normal range.*13

Vitamin B6

An essential coenzyme for normal amino acid metabolism. In particular, vitamin B6 is necessary for the breakdown of homocysteine, an amino acid that plays a supporting role in cardiovascular health.* Also involved in the production of circulating antibodies.13 High levels of circulating vitamin B6 have been associated with reduced levels of C-reactive protein, another important indicator of heart health.*18

Folic Acid        

Another homocysteine lowering agent, folic acid is essential for the formation of red and white blood cells and involved in the synthesis of certain amino acids.*13

Vitamin B12

A ubiquitous coenzyme necessary for DNA synthesis. Also lowers homocysteine levels.*13

Magnesium

Increases HDL levels, supporting a healthy lipid profile, and helps maintain healthy blood pressure already within the normal limits.*19 Magnesium is a constituent of many coenzymes and is required for normal functioning of muscle and nervous tissue.20

Selenium

An essential trace mineral with powerful antioxidant capabilities.*20 Research has revealed that selenium supports cardiovascular function.*21

L-Arginine

An important amino acid and precursor to nitric oxide (NO), which is important for the health of the cardiovascular, immune, and nervous systems.*22 In clinical study, an L-arginine-enriched diet increased good cholesterol levels.*23

L-Carnitine      

A naturally occurring hydrophilic amino acid derivative, both produced in the kidneys and liver and derived from dietary sources. Along with coenzyme Q10, L-carnitine is a key factor in metabolism, supporting the production of cellular energy.*24 Also shown to increase good cholesterol (HDL) levels.*25 L-carnitine supports healthy blood flow.*26

Coenzyme Q10 (CoQ10)

A fat-soluble nutrient present in the mitochondria of virtually all cells, CoQ10 is an essential factor for cellular energy production.27 Also a powerful free radical scavenger, clinically shown support arterial health.*27,28

Supplementation significantly improves good cholesterol levels.*29 Additionally, CoQ10 supports healthy heart contractility and circulation.*

Policosanol

A unique mixture of essential alcohols, including octacosanol, tetracosanol, hexacosanol and triacontanol, derived from sugar cane.30 In a clinical study, supplementation resulted in a 14 percent increase in HDL cholesterol over an 8-week period.*31

Hawthorn Berry Extract

Helps retain healthy cholesterol levels already within the normal range.* Supports the muscle strength of the heart, helping to maintain healthy heart rhythm, contractility, and vascular circulation.*32 A source of antioxidant constituents that protect against oxidative damage.* Supports the health of veins and arteries.*33,34 Also helps maintain healthy blood pressure levels already within the normal ranges.*

Taurine

An essential amino acid, present in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. Possesses both antioxidant and membrane-supportive properties.*35 Helps maintain a healthy lipid profile by increasing good (HDL) cholesterol levels.*36,37

Garlic Bulb

A powerful antioxidant that possesses wide-ranging cardiovascular health benefits.*38 Clinically shown to increase good cholesterol levels, particularly HDL-2 cholesterol.* 39

Grape Seed Extract

A source of free-radical scavenging phytonutrients, known as polyphenols.* Promotes healthy circulation.* Also supports cardiovascular health by increasing HDL cholesterol levels*40,41

N-Acetyl-L-Cysteine (NAC)

A derivative of the amino acid, cysteine, NAC is a key intermediary in the conversion of cysteine into glutathione, one of the body’s primary cellular antioxidants.* Supports the health of the cardiovascular and immune systems.* Also shown to significantly increase in HDL cholesterol.*42

Alpha Lipoic Acid (ALA)

An antioxidant and vital cofactor necessary for the production of cellular energy, ALA helps recycle other important antioxidants, including vitamins C and E, CoQ10, and glutathione. Also helps maintain healthy blood flow and healthy heart contraction.*43

Soy Isoflavones

Provide antioxidant protection, supporting cardiovascular and immune system health.* Soy protein-enriched diet has been shown

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Ola Loa Multi-Vitamin Mineral Formula
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Date: February 22, 2006 06:33 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ola Loa Multi-Vitamin Mineral Formula

Ola Loa

Lets face it. Most people don’t look forward to taking their daily vitamins. Its too complicated; there are too many pills and capsules. You take some with food, some with out. Forget to eat this morning? Put your pills in your pocket and carry them with you to take at lunch or dinner or tomorrow?

With Ola Loa’s single serving packs, getting your daily multi is not only convenient and delicious, but also based on sound nutrition science. That’s the Ola Loa Advantage!

In formulating Ola Loa, Richard Kunin M.D. chose its powerful combination of vitamins, minerals and amino acids based on their functional uses in the body and his 40 years of scientific research and experience giving nutrients to his patients. Nowhere will you find a more strategic and effective collection of nutrients.

Ola Loa Energy formula includes NAC, and Vitamin C (which strengthens antioxidant and immune function), along with six amino acids, CoQ10, and 40 mineral complexes. Ola Loa provides you with enough TMG to lower homocysteine and raise SAME levels. Ola Loa’s nutrients and pleasing taste have almost instant benefits. You will feel a difference.

Ola Loa REPAIR is a great tasting effervescent multi-vitamin powder that provides unparalleled nutrient support for bones, joints, cartilage and the aches and pains of everyday life. REPAIR is recommended for daily bone and joint health, as a general anti-aging vitamin and is a comfort to those concerned about bone health and regular wear-and-tear on joints.

Our convenient grab-and-go packs are easy to bring with you wherever you go. Just pack Ola Loa for your business or pleasure trips or throw a few packets in your brief case, purse or desk drawer. Having Ola Loa around encourages regular vitamin consumption and will give you that boost of nutrients whenever, wherever you need it.



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High Absorption CoQ10
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Date: February 13, 2006 05:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: High Absorption CoQ10

The human heart beats more than two and a half billion times in an average lifetime. The energy required for this miracle of nature is enormous, and maintaining heart tissue energy levels is essential. A vitamin-like nutrient found in the human body, Coenzyme Q10 or CoQ10 supports heart function. Without adequate CoQ10, cells become energy-deficient. When nourished with optimal levels of CoQ10, your body tissues, including the liver, nerves and muscles function optimally. With its high energy requirements, the heart needs to be supplied with CoQ10 at all times. Numerous clinical studies have shown significant improvements in heart function with oral administration of CoQ10. Immune cells need large amounts of energy, and CoQ10 helps make it available. A versatile antioxidant, it stabilizes membranes and protects them from free-radical damage. A fat-soluble nutrient, CoQ10 is difficult to absorb, so we’ve added Bioperine. Preliminary Trails on humans have shown significant increases in absorption of Bioperine-enhanced nutrients. High absorption CoQ10, a pharmaceutical grade supplement, is now available in three different forms: 30mg/60 caps; 100mg/30 caps; and 100mg/60 caps. High Absorption CoQ10 with bioperine


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Molecularly Distilled Omega-3 fish Oil Fact Sheet
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Date: January 12, 2006 03:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Molecularly Distilled Omega-3 fish Oil Fact Sheet

Molecularly Distilled Omega-3 fish Oil Fact Sheet

Neil E. Levin, CCN, DANLA 10/26/04

LIKELY USERS: Everyone consuming fast foods or diets high in vegetable oils; People with family history of heart disease or diabetes; People with inflammatory conditions

KEY INGREDIENT(S): Molecularly distilled fish oil concentrate

MAIN PRODUCT FEATURES:
  • Cholesterol free
  • Natural lemon flavor
  • This oil is easier for many people to tolerate than other fish oils
  • Antioxidant blend of Rosemary Extract, Ascorbyl Palmitate and Natural Tocopherols
  • Natural triglyceride form (unlike some other brands using the ester form)
  • Manufactured and distilled in a pharmaceutical facility in Norway according to pharmaceutical protocols
  • Molecularly distilled and screened for the absence of potentially harmful levels of contaminants (i.e. mercury, heavy metals, PCB's, dioxins, etc.)
  • Derived from open sea catches of sardines and anchovies
  • Also available in unflavored enteric-coated capsules
OTHER IMPORTANT ISSUES:
 
  • Molecular distillation removes impurities such as pesticides (PCBs, PCDFs, PCDDs, Dioxin) and heavy metals (mercury, lead)
  • Exceeds contaminant safety standards per CRN monograph and California state law
  • No trans-fats
  • Consumption of Omega-3 fatty acids may reduce the risk of coronary heart disease. (FDA evaluated the data and determined that, although there is scientific evidence supporting the claim, the evidence is not conclusive.)
  • Helps control triglycerides and prevent excessive clotting>
  • Promotes anti-inflammatory prostaglandins that also encourage dilation of blood vessels
  • Essential for brain, nerves, cell membranes and blood sugar metabolism
  • Aids in maintaining normal heart rhythm

    AMOUNT TO USE: One teaspoon a day provides 740 mg. of EPA and 475 mg. of DHA. Use one or more teaspoons per day.

    SYNERGISTS: Other supplements used as cardiotonics include Vitamin E, CoQ10, magnesium, antioxidants, garlic, ginger, cayenne pepper, L-carnitine and hawthorn leaf and flower extract.

    CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. But no cautions have been noted to date for pregnant or nursing women using fish oils, which are often recommended for pregnant and nursing women.

    Disclaimer:  These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.




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    Your Cells Supercharge Your Cells
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    Date: December 20, 2005 11:30 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Your Cells Supercharge Your Cells

    Your Cells Supercharge Your Cells

    The differences between aging and growing old are poles apart. Sure, they may sound similar in nature. But when you think about it, the two are as different as night and day. Growing old is about retirement and travel and enjoying what you’ve worked an entire life for. Aging, on the other hand, summons images of wrinkled skin, brittle joints, cloudy minds and medicine cabinets full of prescriptions. It’s safe to assume that the majority of us want to look, live, and feel better as we grow old. Not the opposite. Many of us are on the right track - committed to a healthy lifestyle that includes regular exercise and a well-balanced diet. And yes, these do serve as a solid foundation for good health during our golden years. It is our cells, however, that ultimately determine who grows old, and who just ages.

    Still, slowing the proverbial hands of time is not all about health clubs and organic produce. If you want to grow old gracefully, you must nurture the ten trillion cells that defi ne you physically. Why? Because these cells are constantly under attack by free radicals - unstable molecules that either lack, or have an unpaired number of electrons. They scour the body in search of stable cells, and do whatever they can to rob them of their electrons, a process more formally known as oxidation. Considering that it’s environmentally impossible to completely avoid contact with the billions of airborne toxins that cause free radicals, the only other option is to safeguard your healthy cells. Making the commitment to a healthy lifestyle is the fi rst step in the process, and can be accomplished by eating healthier foods, exercising on a regular basis, and paying close attention to what you are exposed to environmentally.

    The next step is to nourish and protect your cells. The best way to do this is to consume foods that are rich in antioxidants and other cell-friendly nutrients. Unfortunately, this task is often much easier said than done. Today’s average adult is busier than ever, making it far more diffi cult to consume fresh, unprocessed meals 100% of the time. This does not, however, imply that all hope is lost. Over the years, the nutritional sciences have made stunning advances that afford you the opportunity to live your life while still safeguarding the integrity of your most basic building blocks. Here are a few of the best.

    Antioxidants

    Antioxidants work at the cellular level to paralyze the free radicals that cause oxidation throughout the body. Some of today’s most popular nutrients and dietary supplements fall into this category. They include vitamins A, E, and C, Selenium, Zinc, Alpha Lipoic Acid, Lycopene, Lutein, CoQ10, in addition to a host of others. And though similar in function, each of these free radical fi ghters has a unique role within the body.

    Take CoQ10 for example. It’s present in every cell of the body, and is especially important for cardiovascular support. Lutein has been used extensively to prevent oxidation in the macular regions of the eyes. Zinc is a powerful immune system booster that has become extremely popular during cold and fl u season. Alpha Lipoic Acid is both fat and water soluble, and is commonly referred to as the “universal” antioxidant based on its ability to quench free radicals anywhere in the body.

    Immune Boosting Herbs

    Herbs such as Astragalus, Olive Leaf, Rhodiola, Echinacea, Panax Ginseng and Ashwaganda have been used for centuries to help support healthy cells and strong, responsive immune systems. They’ve also been shown to exhibit natural synergistic effects when used together. Today, they remain one of the most popular ways to naturally promote all-around wellbeing. When it comes to supporting healthy cells, NOW is pleased to offer one of the best selections of antioxidants, herbs and immune support formulas. Be sure to look for these and other great products at fi ne health food retailers, nationwide.*

    OPCs

    OPCs (proanthocyanidins) are high-powered polyphenol antioxidants that belong to the fl avonoid family. Grape seed extract, pine bark extracts such as pycnogenol and enzogenol, bilberry, gingko biloba, resveratrol and others all fall into this category. Research continues to suggest that OPCs work in the same manner that traditional antioxidants do, however their ability to eradicate free radicals is much greater and more versatile. Equally appealing, OPCs can easily cross the blood barrier of the brain to help protect brain and neural tissues from the damage caused by oxidative stress.

    Mushroom Extracts

    Throughout history, many civilizations have relied on organic mushroom extracts to encourage wellness. What we know now is that mushrooms such as Shiitake, Maitake, Reishi and others are rich in 1,3 Beta-glucans - soluble fi ber compounds that help support both innate and adaptive immunity. In addition, the active compounds in some mushrooms have been shown to stimulate the production of microphages, T cells, and other natural killer cells. These biological warriors serve at the front line when it comes to responding to bacterial attacks. They are of immeasurable value to the immune system, though drastically lacking in today’s average diet. In just the past few years, more and more healthconscious individuals have learned fi rst-hand how benefi cial they can be in the preservation of healthy cells.



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    GliSODin Anti-Aging and Antioxidant Protection
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    Date: December 19, 2005 08:47 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GliSODin Anti-Aging and Antioxidant Protection

    GliSODin Anti-Aging and Antioxidant Protection

    • Superior Anti-Aging Formula
    • Stimulates Natural Antioxidant Defenses
    • Helps Protect DNA
    • Reduces Oxidative Stress
    • Prevents Oxygen Related Cell Damage

    In the time it takes you to finish reading this article, you, your body and your cells will have aged. Some, more than others. Nevertheless, every second that ticks away should serve as a reminder that our time here is temporary. How much time we actually end up with depends on many things. Diet. Lifestyle. Environment. Superoxide Dismutase? I’ll explain. What some of the healthiest individuals fail to realize is that our bodies age from the inside out. Aging is not the result of passing time, but rather the result of what we’re exposed to environmentally, physically and chemically. It is the integrity of our cells, not our clocks, that determine how smooth the aging process fares.

    Each day, we’re subjected to millions of elements that affect us in ways seldom seen, felt or noticed. From the moment we’re born, we rely on our cells to work around the clock - producing energy, fighting infections and sustaining life. These same cells eventually determine the rate at which we show (or hide) our age.

    Taking into consideration that our planet has no shortage of toxins & germs, the need to safeguard our cells becomes very real. Constant exposure to exhaust, secondhand smoke, heavy metals, lead, fluoride and uncountable other noxious compounds should ideally provide us with nothing more than a routine immune system workout. Unfortunately, over long periods they hinder our “resistance” abilities and become stepping stones to accelerated aging.

    Antioxidants. We’ve all heard the term before, and may even have a general understanding of their role. But to better grasp just how vital they are, it helps to know what’s happening at the cellular level. Free radicals are unstable molecular thieves that often lack electrons. To compensate, they rob healthy cells - a process better known as oxidation. Antioxidants work with the immune system to prevent oxidation, and clean up the mess it leaves behind. Hence, the name.

    There are two types. Exogenous antioxidants are derived from our diet and include vitamins A, E, and C along with others such as alpha lipoic acid, selenium, CoQ10, grape seed, pycnogenol and zinc. To date, we’ve been limited to exogenous antioxidants as a way to increase the rate at which our body wards off oxidation. They are not, however, our first line of defense. At birth, each and every one of us is equipped with three primary endogenous enzymatic antioxidants; SOD (Superoxide Dismutase), Glutathione Peroxidase (GPx) and Catalase.

    While both types of antioxidants are beneficial, we’ve become reliant on those from the diet to compensate for our inability to boost the effectiveness of our 3 primary antioxidants. For years, researchers have been examining ways to enhance the activity of our built-in bodyguards. One in particular, Superoxide Dismutase (SOD) has been of foremost interest. SOD targets what many researchers regard as one of our greatest health threats and aging accelerators - Superoxide radicals. These highly reactive, merciless molecules incite enormous amounts of oxidative stress and are capable of wreaking havoc on healthy cells. When cells are left unprotected by SOD, the results can be disastrous - respiratory problems, premature aging, memory loss, cardiovascular challenges, vision failure and joint structure damage, among others.

    Until now, we’ve been at the mercy of our natural SOD reserves to fight superoxides. Researchers have been working feverishly to produce an effective oral SOD supplement, but have continually encountered a frustrating hurdle - exposure to gastric acid denatures SOD, rendering it useless. As a result, the only effective way to supplement SOD was through injections. These, however, only yielded short-term spikes. And then something remarkable happened that changed everything. Nutrition scientists in France determined that by combining Cucumus melo (a melon high in SOD) with a wheat gliadin stabilizer, it would be possible to prevent SOD from deteriorating in the digestive tract, while preserving it in the blood for extended periods. Not only is this the answer to a puzzle that has plagued researchers, it’s a breakthrough that will impact the life of anyone seeking longevity and vitality.

    As the first proven oral SOD supplement ever introduced to the public, GliSODin® has taken antioxidant protection, immune support and antiaging science to an entirely new level. The primary function of GliSODin® is to scour the body for superoxide radicals and reduce them to less reactive ions that can be swept away; a process known as dismutation. In addition, GliSODin® reduces the oxidation vulnerability of healthy cells, protects mitochondrial activity and safeguards DNA structure.

    What’s most remarkable is that GliSODin® has actually been shown to stimulate the body’s own natural production of all three enzymatic antioxidants, including SOD. For the first time in history, we will have the ability to enhance the effectiveness of our body’s primary defense mechanism.

    New GliSODin® from NOW® represents the ultimate in antioxidant protection. By increasing one’s level of SOD while stimulating the natural production of Glutathione Peroxidase and Catalase, GliSODin® delivers antioxidant protection unlike any previously released dietary supplement. Remember, the aging process begins at a level that we simply can not see, the cellular level. Shielding your cells from superoxide damage is one of the smartest steps you can take against aging before your due time. GliSODin® has made this a reality.



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    Coenzyme Q10 and Cardiovascular Health.
    TopPreviousNext

    Date: December 13, 2005 11:34 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Coenzyme Q10 and Cardiovascular Health.

    CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function!

    CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body.

    CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits.

    As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.”

    “The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication.

    Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.



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    Tru-E Bio Complex
    TopPreviousNext

    Date: December 08, 2005 04:58 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Tru-E Bio Complex

    Tru-E Bio Complex TM

    Neil E. Levin, CCN, DANLA 7/27/05

    LIKELY USERS: Most Americans are deficient in Vitamin E 8,9,10; People needing superior antioxidant protection3,5,6; People needing cardiovascular or cholesterol support27,30,31; People needing nervous system support7; Those wanting healthier skin6; Diabetics may need additional Vitamin E24 KEY INGREDIENTS: Tocopherols from IP-Preserved, non-GMO Soy; Tocotrienols and tocopherols from non-GMO virgin palm; Tocotrienols from non-GMO annatto seed

    MAIN PRODUCT FEATURES: NOW Tru-E Bio ComplexTM is a unique biologically balanced, patent-pending formula designed to provide optimal Vitamin E activity. This product features 100% natural, Non-Genetically Modified sources of all 8 isomers (forms) of the Vitamin E “family” in ratios similar to what is found in a healthy diet. It provides the superior benefits of foodsource Vitamin E versus those obtained from traditional E supplements.

    NOW® Tru-E Bio ComplexTM has been carefully blended to supply high levels of the natural gamma and delta “desmethyl” forms of both tocopherols and tocotrienols. This is important because recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues. This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants. This science-based natural Vitamin E supplement is unlike any other and the first to combine all of these benefits in one convenient non-GMO formula! 25-32

    Recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues.1-4, 25-32

    This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants.1,4-7

    Levels of Vitamin E above 100 IU daily are associated with decreased risk of coronary heart disease and certain types of cellular disorders, as well as enhancement of immune function. These vitamin E intakes are considerably above levels obtainable from diet alone. 11,12,13

    ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

    This is a product that is Patent Pending, based on months of research into optimal forms, potencies and ratios of the 8 isomers of natural Vitamin E. All of the Vitamin E formulas currently on the market use potencies of tocopherols that are very dissimilar to what is found in a healthy diet, with either too low or too high amounts of gamma and alpha tocopherols for a good balance. Some do not even include tocotrienols.

    All of the Vitamin E formulas on the market that do contain a mixture of tocopherols and tocotrienols tend to use either 400 IU or 100 IU of alpha tocopherol, some as little as 50-60 IU, combined with varying doses of gamma tocopherol. We have reduced the alpha tocopherol from the standard 400 IU per capsule to 200 IU, allowing more gamma tocopherol in the capsule to follow the typical ratio in a healthy diet. Other brands either cut the alpha tocopherol too low (to keep the gamma tocopherol at a good level) or else cut the gamma and other tocopherols too low (to keep the alpha tocopherol at 400 IU).

    Special care was used to maintain a certain ratio of tocopherols and of tocotrienols that is unique and from natural sources. Our formula is also unique in mixing sources of tocotrienols to achieve our desired balance, whereas other formulas include only one source, despite the dissimilarity of the mixture to what is found in a healthy, varied diet.

    Other formulas use either Vitamin E derived from genetically engineered soybeans and/or add soybean oil from similar sources as a base. NOW uses expensive non-GMO sources, the first formula to do so, with no soybean oil added. This enhances the quality of our product compared to every other formula on the market.

    We use the expensive virgin palm oil rather than the cheap palm distillates because it is un-denatured and contributes additional, valuable oil nutrients such as CoQ10, Squalene and Sterols. Also, much of the clinical research done on tocotrienols was done using virgin palm oil sources 32

    Natural Vitamin E is more effective than synthetic Vitamin E.14 - 23

    SERVING SIZE & HOW TO TAKE IT: One or two capsules per day, preferably with meal(s). Oils enhance the absorption of Vitamin E. Concentrated fiber supplements may decrease the absorption of Vitamin E, so it is best not to take both at the same meal.

    SYNERGISTS: Antioxidants (Alpha Lipoic Acid, Vitamin C Complex, Pine or Grapeseed Extracts, VitaBerry Plus+, CoQ10, etc.), Plant Sterols, Fish Oil, Flaxseed Oil, GliSODin, EGCg Green Tea Extract, Lecithin, Nuts and Seeds

    CAUTIONS: None.

    SPECIFIC: Aspirin and blood thinners should not be taken with Vitamin E without physician’s approval. Many other pharmaceutical drugs deplete Vitamin E, adding to the likelihood that a person will be deficient.

    GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

    REFERENCES:

    1. Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) g-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74:714-722.
    2. Schneider C (2005) Chemistry and biology of vitamin E. Mol Nutr Food Res 49(1):7-30.
    3. Pfluger P, Kluth D, Landes N, Bumke-Vogt C, Brigelius-Flohe R (2004) Vitamin E: underestimated as an antioxidant. Redox Rep 9(5):249-254.
    4. Liu M, Wallin R, Saldeen (2002) Effect of mixed tocopherols on ecNOS, SOD, and PKC in leukocytes in human subjects. Nutr Res 22:1253-1263.
    5. Saldeen T, Li D, Mehta JL (1999) Differential Effects of a- and g-Tocopherol on Low-Density Lipoprotein Oxidation, Superoxide Activity, Platelet Aggregation and Arterial Thrombogenesis. J Am Coll Cardiol 34:1208-1215.
    6. "Packer L, Valacchi G. (2002) Antioxidants and the response of skin to oxidative stress: vitamin E as a key indicator. Skin Pharmacol Appl Skin Physiol 15(5):282-90."
    7. Sen CK, Khanna S, Roy S. (2004) Tocotrienol: the natural vitamin E to defend the nervous system? Ann N Y Acad Sci 1031:127-42.
    8. Dial S, Eitenmiller RR. 1995. Tocopherols and tocotrienols in key foods in the U.S. diet. In: Ong ASH, Niki E, Packer L, eds. Nutrition, Lipids, Health, and Disease. Champaign, IL: AOCS Press. Pp. 327–342.
    9. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000). Institute of Medicine
    10. JASPREET K.C. AHUJA, JOSEPH D. GOLDMAN, and ALANNA J. MOSHFEGH. Current Status of Vitamin E Nutriture. Ann NY Acad Sci 2004 1031: 387-390.
    11. Bauernfeind, J. Tocopherols in Foods. In: Vitamin E: A Comprehensive Treatise. Marcel Dekker, Inc., New York and Basel, pp. 99-167, 1980.
    12. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
    13. Weber, P., Bendich, A. and Machlin, L.J. Vitamin E and Human Health: Rationale for Determining Recommended Intake Levels. Nutrition 13:450-460, 1997.
    14. Acuff RV et al. Am. J. Clin. Nutr. 1998;67:459-64
    15. Acuff RV et al, Am. J. Clin. Nutr. 1994, 60:397-402
    16. Behrens, W.A. and Madere, R. Tissue Discrimination between Dietary RRR-Alpha- and All-Rac-Alpha-Tocopherols in Rats. J. Nutr. 121:454-459, 1991.
    17. Burton G et al, Am. J. Clin. Nutr. 1998,67:669-84
    18. Ferslew, K.E., Acuff, R.V., Daigneault, E.A., Woolley, T.W. and Stanton, P.E. Pharmacokinetics and Bioavailability of the RRR and All Racemic Stereoisomers of Alpha-Tocopherol in Humans after Single Oral Administration. J. Clin. Pharmacol. 33:84-88, 1993.
    19. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
    20. Ogihara, T., Nishida, Y., Miki, M. and Mino, M. Comparative Changes in Plasma and RBC Alpha-Tocopherol after Administration of dl-Alpha-Tocopheryl Acetate and d-Alpha-Tocopherol. J. Nutr. Sci. Vitaminol. 31:169-177, 1985.
    21. Traber M et al, FEBS Letters 1998,437:145-148
    22. Traber MG, et al. J Lipid Res. 1990,31(4):675-85
    23. Weiser, H. and Vecchi, M. Stereoisomers of Alpha-Tocopheryl Acetate. II. Biopotencies of All Eight Stereoisomers, Individually or in Mixtures, as Determined by Rat Resorption-Gestation Tests. Internat. J. Vit. Nutr. Res. 52:351-370, 1982.
    24. Polidori MC, Mecocci P, Stahl W, et al. Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diabetes Metab Res Rev 2000;16:15–9.
    25. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, and Mordan LJ. gamma-Tocopherol Detoxification of Nitrogen Dioxide: Superiority to alpha-Tocopherol. PNAS 1993; 90: 1771-1775.
    26. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr. 2005 Feb;81(2):508-14. PMID: 15699242
    27. Inokuchi H, Hirokane H, Tsuzuki T, Nakagawa K, Igarashi M, Miyazawa T. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317
    28. Kline K, Yu w, Sander BG, et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. (1999), Nutr Cancer, 33 : pp : 26 – 32
    29. The Chicago Health and Aging Project, Martha Clare Morris, Denis A Evans, Christine C Tangney, Julia L Bienias, Robert S Wilson, Neelum T Aggarwal and Paul A Scherr. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. American Journal of Clinical Nutrition, Vol. 81, No. 2, 508-514, February 2005
    30. Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388
    31. Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Hypocholesterolemic activity of synthetic and natural tocotrienols. J Med Chem. 1992 Oct 2;35(20):3595-606. PMID: 1433170
    32. Soelaiman IN, Ahmad NS, Khalid BA. Palm oil tocotrienol mixture is better than alpha-tocopherol acetate in protecting bones against free-radical induced elevation of bone-resorbing cytokines. Asia Pac J Clin Nutr. 2004 Aug;13(Suppl):



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    Carnitine Creatinate
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    Date: December 08, 2005 03:33 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Carnitine Creatinate

    Carnitine Creatinate

    Neil E. Levin, CCN, DANLA 6/30/05

    LIKELY USERS: Athletes, Bodybuilders, Dieters, People who consume a lot of fat, People needing cardiovascular support (energy for the heart), People who need quick energy, especially for fast muscle response, People with muscle wasting problems (including the elderly), Weightlifters

    KEY INGREDIENTS: L-Carnitine and Creatine Monohydrate

    MAIN PRODUCT FEATURES: Carnitine Creatinate Monohydrate is a specialized form of Creatine bonded to L-Carnitine. Creatine is a compound natural to the human body that aids in the regeneration of ATP, the chemical energy used by muscle tissue. During exercise, large quantities of creatine are irreversibly consumed. Clinical studies have shown that oral supplementation with Creatine can increase the amount of Creatine available in muscles for ATP production. L-Carnitine is an amino acid that is necessary for the transfer of fatty acids into the fat-burning parts of the cell, facilitating energy production from fat. The combination of these two compounds can produce a synergistic effect, making NOW® Carnitine Creatinate an ideal energy supplement.

    ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: Carnitine and Creatinate Monohydrate is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product. Protected by U.S. Patent No. 5,994,581 (L-Carnitine Creatinate Monohydrate).

    Look at the price: this is a better way to buy both supplements than purchasing them separately.

    This formula is suitable for vegetarians and is offered in both tablet and powder forms.

    SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every two tablets provide 1,000 mg. (one gram) each of both L-Carnitine and Creatine Monohydrate. Or one teaspoon provides 1,150 mg.) each of both L-Carnitine and Creatine Monohydrate. Take one or more servings per day with a carbohydrate source, such as fruit juice or sports drinks.

    COMPLEMENTARY PRODUCTS: CoQ10, carbohydrates, B-Complex vitamins, chromium, vanadium, Hawthorn leaf and flower extract, protein supplements. Adaptogenic herbs: ginsengs, Eleuthero, Rhodiola, Maca, Ashwaganda, licorice root

    CAUTIONS: none.

    PRODUCT SPECIFIC: This product is very sensitive to moisture. Please keep in the original packaging or in a moisture resistant container. Do not take more than 20 grams per day. Discontinue use if cramps of stomach upset occur, especially if taking large doses. Do not take if kidney disease is present. Do not use large doses of caffeine with creatine, as it may increase the possibility of muscle cramping.

    GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems.

    Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

    Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

    REFERENCES:

    Fang S-M (1998) Carnitine Creatinate. U.S. Patent 5,994,581.

    L-CARNITINE:

    Beers MH, Berkow R (eds). The Merck Manual of Diagnosis and Therapy, 17th ed. Whitehouse Station, NJ: Merck and Co., Inc, 1999, 881-3.

    Broquist HP (1994) Carnitine, in Modern Nutrition in Health and Disease, 8th ed., Shils ME, Olson JA, Shike M (eds.) Lea & Febiger, Philadelphia, pp. 459-465. Casey A, Greenhoff PL (2000) Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance? Am J Clin Nutr 72(suppl):607S-17S. Columbani P, Wenk C, Kunz I, et al. Effect of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double blind crossover field study. Eur J Appl Physiol 1996;73:434-9.

    Dal Negro R, Pomari G, Zoccatelli O, Turco P. L-carnitine and rehabilitative respiratory physiokinesitherapy: metabolic and ventilatory response in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1986;24:453-6.

    Dal Negro R, Turco P, Pomari C, De Conti F. Effects of L-carnitine on physical performance in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1988;26:269-72.

    Del Favero A. Carnitine and gangliosides. Lancet 1988;2:337 [letter].

    Dipalma JR. Carnitine deficiency. Am Fam Physician 1988;38:243–51.

    Digiesi V, Palchetti R, Cantini F. The benefits of L-carnitine in essential arterial hypertension. Minerva Med 1989;80:227-31.

    Giamberardino MA, Dragani L, Valente R, et al. Effects of prolonged L-carnitine administration on delayed muscle pain and CK release after eccentric effort. Int J Sports Med 1996;17:320-4.

    Green RE, Levine AM, Gunning MJ. The effect of L-carnitine supplementation on lean body mass in male amateur body builders. J Am Diet Assoc 1997;(suppl):A-72.

    Harris RC, Soderlund K, Hultman E (1992) Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci 83(3):367-374.

    Kendler BS. Carnitine: an overview of its role in preventive medicine. Prev Med 1986;15:373–90.

    Kobayashi A, Masumura Y, Yamazaki N. L-carnitine treatment for congestive heart failure—experimental and clinical study. Jpn Circ J 1992;56:86–94.

    Murray MT. The many benefits of carnitine. Am J Natural Med 1996;3:6-14 [review].

    Tamamogullari N, Silig Y, Icagasioglu S, Atalay A. Carnitine deficiency in diabetes mellitus complications. J Diabetes Complications 1999;13:251–3.

    Yesilipek MA, Hazar V, Yegin O. L-Carnitine treatment in beta thalassemia major. Acta Haematol 1998;100:162-3. CREATINE MONOHYDRATE: Almada A, Mitchell T, Earnest C. Impact of chronic creatine supplementation on serum enzyme concentrations. FASEB J 1996;10:4567.

    Becque MD, Lochmann JD, Melrose DR. Effects of oral creatine supplementation on muscular strength and body composition. Med Sci Sports Exerc 2000;32:654-8.

    Casey A, Constantin-Teodosiu D, Howell S, et al. Creatine supplementation favorably affects performance and muscle metabolism during maximal intensity exercise in humans. Am J Physiol 1996;271:E31-E7.

    Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci 1996;91:113-8.

    Earnest C, Almada A, Mitchell T. Influence of chronic creatine supplementation on hepatorenal function. FASEB J 1996;10:4588.

    Earnest CP, Snell PG, Rodriguez R, et al. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 1995;153:207-9.

    Felber S, Skladal D, Wyss M, et al. Oral creatine supplementation in Duchenne muscular dystrophy: a clinical and 31P magnetic resonance spectroscopy study. Neurol Res 2000;22:145-50.

    Feldman EB. Creatine: a dietary supplement and ergogenic aid. Nutr Rev 1999;57:45–50.

    Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in man. Am J Physiol 1996;271:E821–6.

    Green AL, Simpson EJ, Littlewood JJ, et al. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. Acta Physiol Scand 1996;158:195-202.

    Greenhaff PL. Creatine and its application as an ergogenic aid. Int J Sport Nutr 1995;5:94-101.

    Greenhaff PL. The nutritional biochemistry of creatine. J Nutr Biochem 1997;8:610-8 [review].

    Greenhaff PL, Bodin K, Soderlund K, et al. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am J Physiol 1994;266:E725-30.

    Greenhaff PL, Casey A, Short AH, et al. Influence of oral creatine supplementation on muscle torque during repeated bouts of maximal voluntary exercise in man. Clin Sci 1993;84:565-71.

    Harris RC, Soderlund K, Hultman E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci 1992;83:367-74.

    Hultman E, Soderlund K, Timmons J, et al. Muscle creatine loading in man. J Appl Physiol 1996;81:232–7.

    Juhn MS, O’Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593–5.

    Kreider RB, Ferreira M, Wilson M, et al. Effects of creatine supplementation on body composition, strength, and sprint performance. Med Sci Sports Exerc 1998;30:73-82.

    Poortmans JR, Auquier H. Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men. Eur J Appl Physiol Occup Physiol 1997;76:566–7.

    Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108–10.

    Pritchard NR, Kaira PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252–3 [letter].

    Sewell DA, Robinson TM, Casey A, et al. The effect of acute dietary creatine supplementation upon indices of renal, hepatic and haematological function in human subjects. Proc Nutr Soc 1998;57:17A.

    Silber ML. Scientific facts behind creatine monohydrate as a sports nutrition supplement. J Sports Med Phys Fitness 1999;39:179–88 [review].

    Sipila I, Rapola J, Simell O, et al. Supplementary creatine as a treatment for gyrate atrophy of the choroid and retina. N Engl J Med 1981;304:867-70.

    Stone MH, Sanborn K, Smith LL, et al. Effects of in-season (5-weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 1999;9:146-65.

    Stout JR, Eckerson J, Noonan D, et al. The effects of a supplement designed to augment creatine uptake on exercise performance and fat-free mass in football players. Med Sci Sports Exerc 1997;29:S251.

    Tarnopolsky MA. Potential benefits of creatine monohydrate supplementation in the elderly. Curr Opin Clin Nutr Metab Care 2000;3:497-502 [review].

    Tarnopolsky M, Martin J. Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology 1999;52:854-7.

    Tarnopolsky MA, Roy BD, MacDonald JR. A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies. Muscle Nerve 1997;20:1502-9.

    Toler SM. Creatine is an ergogen for anaerobic exercise. Nutr Rev 1997;55:21-5 [review].

    Vandenberghe K, Gills N, Van Leemputte M, et al. Caffeine counteracts the ergogenic action of muscle creatine loading. J Appl Physiol 1996;80:452–7.

    Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training. J Appl Physiol 1997;83:2055-63.

    Walter MC, Lochmuller H, Reilich P, Klopstock T, Huber R, Hartard M, Hennig M, Pongratz D, Muller-Felber W. Creatine monohydrate in muscular dystrophies: A double-blind, placebo-controlled clinical study. Neurology. 2000 May 9;54(9):1848-50. PMID: 10802796

    Walter MC, Reilich P, Lochmuller H, Kohnen R, Schlotter B, Hautmann H, Dunkl E, Pongratz D, Muller-Felber W. Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study. J Neurol. 2002 Dec;249(12):1717-22. PMID: 12529796



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    Skin Eternal #1 Skin Care Line – Source Naturals
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    Date: November 04, 2005 09:16 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Skin Eternal #1 Skin Care Line – Source Naturals

    Skin Eternal #1 Skin Care Line – Source Naturals

    November is National Skin Health Month! It’s also a time of year when exposure to stormy winter weather and overheated rooms can play havoc with skin. Source Naturals #1 Skin Eternal line can help nourish and recondition dry, chapped and irritated skin.

    Source Naturals Skin Eternal skin care products in Whole Foods magazines annual Natural Choice Awards for two years in a row!

    Skin Eternal products enhance skin tissue with breakthrough ingredients that go deep to the cellular level to recharge and revitalize delicate skin. These include alpha lipoic acid, CoQ10, vitamin C ester, DMAE, plus a wide variety of nutrients and plant extracts. This premier line includes luxurious cosmetic products as well as supplements that support healthy skin from the inside out.



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    CoQsol-CF™provides all the well-known benefits of CoQ10
    TopPreviousNext

    Date: July 26, 2005 03:11 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CoQsol-CF™provides all the well-known benefits of CoQ10

    CoQsol-CF™provides all the well-known benefits of CoQ10.

    CoQ10 works at the cellular level to produce energy for metabolism in the form of ATP. It serves as a vital link in the "electron transport chain," which is the final step in the production of ATP in the mitochondria of cells. When cells are nourished with optimal levels of CoQ10, tissues, organs and systems function properly.

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    LIFE FORCE MULTIPLE - Essential Nutrients to Support Your Low Carb Lifestyle..
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    Date: June 29, 2005 10:39 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: LIFE FORCE MULTIPLE - Essential Nutrients to Support Your Low Carb Lifestyle..

    Life Force Multiple

    Taking care of your body is an especially important challenge in today’s stressful and hectic world. Choosing a low carb lifestyle is an increasingly popular way to seek better health. In fact, there are approximately 30 million U.S. adults counting their carbs right now. While effective for weight control and therefore having positive health effects, low carb approaches can also result in serious nutrient imbalances. Thus, adding the right multiple to your low carb approach is an enormously important next step for your good health. LIFE FORCE MULTIPLE, the top-ranked and award–winning multiple from Source Naturals, replenishes these nutrients and provides compounds that will help your body process the increased proteins and fats better while you are restricting carbs.

    Low Carb Benefits

    Restricting carbs can have many health benefits. And lowering your intake of refined simple carbs, such as sugar and white flour, can help you promote healthy blood sugar and insulin levels, which is critical for your good health. Insulin is used to move the glucose from carbs into your cells for energy. Ingesting too many refined carbs can greatly reduce your body’s ability to use insulin well, which can lead to short and long-term health concerns.

    Replenish Nutrients with LIFE FORCE

    LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient dense foods such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including beta-carotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products such as calcium, potassium, vitamin A and vitamin D.

    Support Healthy Fat and Protein Consumption with Life Force

    Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, N-Acetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.

    Restricting simple carbs can do much more than help you maintain a healthy weight; it can also be the foundation for maintaining good health throughout your long life. But you need to develop a thoughtful holistic strategy for success. When you integrate LIFE FORCE MULTIPLE into your wellness plan, then you can benefit from decades of clinical research about the nutrients your body needs to support optimal health and a low carb lifestyle, long before this information becomes part of mainstream health recommendations. Join this wellness revolution by adding LIFE FORCE to your strategies for health and allow yourself to start feeling energized today!

    References
    Marchione, M. (2004). Eating Lots of Carbs May Raise Cancer Risk. Associated Pres. Available at com/news?tmpl=story&u= /ap/20040806/ap_on_he_me/fit_cancer___carbs . Warner, J. (2004). Have We Gone Carb Crazy? Experts Clear Up the Confusion Over the Low-Carb Craze. WebMD. Available at ent/ Article/83/97595.htm?pagenumber=2 . Whitney, E. N., et al. (1998). Understanding Normal and Clinical Nutrition. Wadsworth Publishing Company, Belmont, CA. 325-484.



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    Life Force - The Energy Activator
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    Date: June 29, 2005 10:35 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Life Force - The Energy Activator

    Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100%

    We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating.

    Bio-Align™ Yourself with Life Force

    LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.

    Get Ahead with Activated Energy and a Healthy Metabolism

    Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.

    LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.

    Protect Your Heart and Circulatory System

    The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.

    Skin and Musculoskeletal Support

    LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.

    Brain and Nerves Nutrition

    The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.

    Immune Defense

    LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.

    Powerful Liver Support

    Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.

    Complete Antioxidant Defense

    Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.

    Cutting-Edge Vision Nutrition

    The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.

    Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle

    LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.

    Support Healthy Fat and Protein Consumption with Life Force

    Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.

    Complete Energizing Nutrition

    LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!

    References
    Guyton, A. 1991. Textbook of Medical Physiology, Eighth Ed. W.B. Saunders Co., Philadelphia, PA. Halliwell, B. and Gutteridge, J. 1995. Free Radicals in Biology and Medicine. Clarendon Press, Oxford. Linder, M. 1991. Nutritional Biochemistry and Metabolism, Second Ed. Appleton and Lange, Norwalk, CT. Mathews, C. and van Holde, K.E. 1990. Biochemistry. The Benjamin Cummings Publishing Co., Inc. Shils, M. and Young, V. 1980. Modern Nutrition in Health and Disease, Sixth Ed. Lea & Febiger, Philadelphia, PA.



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    SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...
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    Date: June 29, 2005 09:44 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...

    SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...

    Maintaining your cardiovascular health is one of the best ways you can stay fit. That means working to keep your cholesterol levels within the normal range. And contrary to popular belief, the amount of cholesterol you consume in food is not the most important factor for regulating normal cholesterol levels. It is actually the liver’s imbalanced production of cholesterol that is much more critical for your cardiovascular health.

    You can address the root cause of maintaining normal cholesterol levels today with Source Naturals SYTRINOL™. This patented blend of citrus polymethoxylated flavones and tocotrienols has been clinically shown to promote cardiovascular health by supporting normal cholesterol production by your liver, promoting balanced triglyceride (fat) production, and providing antioxidant protection. Source Naturals, an industry leader in many categories, introduces the science of SYTRINOL™ in the CHOLESTEROL RESCUE™ product family to support your better heart health today.

    The Truth About Cholesterol

    Cholesterol is a very confusing subject – our bodies require it but we can also get too much of it. Cholesterol is one type of the ring-shaped compounds called sterols. Other sterols include bile acids, sex hormones, adrenal hormones and vitamin D. Approximately 90% of the cholesterol in your body is in your cell membranes. The remaining 10% can be found in your blood and throughout your body.

    Liver’s Over-Production of Cholesterol

    When your body needs more cholesterol, your liver takes carbohydrates, proteins and fats (also called triglycerides) from your diet and converts them into cholesterol. The amount of cholesterol that you might consume from foods (in animal products such as eggs, milk, cheese and beef ) is minute compared to the amount of cholesterol produced by your liver. Thus, cholesterol from food isn’t as critical to your total cholesterol. But balancing the cholesterol produced by your liver is very critical to your total cholesterol and thus, your cardiovascular health.

    Oxidized LDL Cholesterol

    Despite the confusion, cholesterol is a vital component of good health that strengthens cell membranes and provides building blocks for hormones, bile and vitamin D production. However, there is one potential pathway where cholesterol can contribute to an imbalance. When cholesterol moves through the blood to individual cells, it can travel in groups such as lipoproteins, which also contain fats and proteins. When the cholesterol is moving through your blood in Low Density Lipoproteins (LDL) it can undergo oxidation by free radicals in the artery walls. Some medical experts theorize that the oxidized LDL cholesterol becomes trapped in the artery walls as imbalanced deposits instead of completing the journey to join cell membranes. These deposits can eventually reduce the size and function of the arteries, compromising blood flow. Thus, antioxidant protection, balanced triglyceride production, and normal cholesterol production by the liver can all be critically important to your good health. And SYTRINOL™ provides all of these benefits.

    How SYTRINOL™ Supports Heart Health

    SYTRINOL is a powerful scientifically formulated blend protected by U.S. patent numbers 6,251,400, 09/ 481724. It contains natural citrus polymethoxylated flavones (PMFs) and tocotrienols that go deep to address the root causes of cholesterol wellness.

    Citrus PMFs

    Polymethoxylated flavones are types of polyphenolic compounds called flavonoids, which are the largest known category of phytonutrients. Health benefits of various flavonoids include antioxidant activity, immune system support, and cellular protection. The unique structure of polymethoxylated flavones, which naturally contain methyl groups paired with oxygen in key places, enables PMFs to interfere with cholesterol production. The citrus PMFs in SYTRINOL, such as tangeretin and sinensetin, promote normal cholesterol levels by inhibiting both the production of cholesterol precursors, such as cholesteryl esters, and the activity of HMG CoA Reductase, an enzyme that synthesizes cholesterol in the liver. These PMFs can also balance the body’s production of triglycerides by inhibiting the activity of your liver’s triglyceride producing enzyme, diacylglycerol acetyltransferase. Since LDL cholesterol is made from cholesterol and triglycerides, decreasing your liver’s production of triglycerides will reduce the amount of those triglycerides available to form LDL cholesterol compounds.

    Tocotrienols

    Tocotrienols are compounds similar to vitamin E in structure and function. The tocotrienols in SYTRINOL increase degradation of cholesterol building blocks such as Apolipoprotein B, interfere with cholesterol production, and provide antioxidant protection. The tocotrienols in SYTRINOL are also especially protective antioxidants for LDL cholesterol compounds that have already been produced, helping to prevent the oxidized LDL cholesterol conditions that may affect your cardiovascular circulation.

    SYTRINOL’s Proactive Synergy

    SYTRINOL works so well because this natural blend of PMFs and tocotrienols works proactively, synergistically, and independently. In preliminary human research, SYTRINOL proactively supported balanced cholesterol and triglyceride production by the liver through the synergistic effects of the PMFs and tocotrienols. Furthermore, SYTRINOL promotes LDL cholesterol antioxidant protection.

    The above information has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

    Other products work reactively to disable existing cholesterol and may only work in conjunction with diets. And because SYTRINOL works independently of diet, you can take it anytime.

    Three Lifestyle Strategies for Cardiovascular Health

    1. Exercise regularly to increase hearthealthy HDL cholesterol and lower blood triglycerides (fats).

    2. Eat a healthy diet rich in fruits, vegetables, whole grains, and lean proteins to help maintain normal cholesterol and triglyceride levels.

    3. Take the right supplements to promote your cardiovascular health. In preliminary clinical studies, the amino acid L-ARGININE supported healthy blood flow to the heart and body. GARLIC OIL helps to maintain healthy cholesterol levels and promotes healthy circulation. POLICOSANOL CHOLESTEROL COMPLEX, CHOLESRESPONSE™, CHOLESFIBER™, CHOLESTREX®, and GRAPEFRUIT PECTIN all help to support normal cholesterol levels. HEART RESPONSE™ and HEART SCIENCE™ are advanced formulas that address heart health. Additionally, you can get cardiovascular system supporting compounds such as folic acid, betacarotene, CoQ10, lipoic acid, ginkgo, grapeseed extract, hawthorn extract, magnesium, vitamin E, and many other nutrients in LIFE FORCE MULTIPLE™, Source Naturals’ best-selling multiple. There is a revolution underway in natural health consciousness, and your local health food store is at the forefront. You can benefit right now – long before word spreads to the general public – with the innovative heart nutrition of SYTRINOL, a CHOLESTEROL RESCUE™ product. SYTRINOL™ is a trademark of KGK Synergize exclusively licensed worldwide to SourceOne Global Partners.

    References
    Guthrie, N. and Kurowska, E.M. (2000). Anticancer and Cholesterol-Lowering Activities of Citrus Flavonoids. Handbook of Nutraceuticals and Functional Foods, Wildman, R.E.C, Ed., CRC Press, Boca Raton, FL, 113-126. Guthrie, N. and Kurowska, E.M. (2000). Anticancer and Cholesterol-Lowering Activities of Tocotrienols. Handbook of Nutraceuticals and Functional Foods, Wildman, R.E.C, Ed., CRC Press, Boca Raton, FL, 269-280.



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    SPECIFIC ACTIONS ASSOCIATED WITH GARLIC
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    Date: June 25, 2005 10:34 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: SPECIFIC ACTIONS ASSOCIATED WITH GARLIC

    SPECIFIC ACTIONS ASSOCIATED WITH GARLIC

  • • Antioxidant: Protects cells against damage by free radicals found in environmental pollutants including heavy metals. Garlic contains the highest level of the antioxidant selenium, which affords excellent cellular protection.
  • • Anti-toxic: Can be considered a radiation antidote in that it stimulates cellular detoxification.
  • • Anti-cancer: Blocks the ability of carcinogens to mutate healthy cells into malignant ones. In some cases, Garlic can even inhibit the early proliferation of cancerous cells.
  • • Decongestant: Helps to rid the respiratory tract of mucus.
  • • Artery Cleanser: Significantly lowers blood levels of triglycerides which have been associated with an increased risk of heart attack.
  • • Anti-artherosclerotic: Promotes the regression of fatty deposits in blood vessels, a major cause of atherosclerosis, and can even help reverse arterial blockages caused by the collection of plaque.
  • • Antibiotic: Works as an immune system stimulant which helps the body fight bacterial, viral and fungal infections. Enhancing immune defenses may also help the body rid itself of cancerous invaders.
  • • Anticoagulant: Reduces the tendency of the blood to clot and helps to dissolve existing clots. Both of these actions are very significant in reducing the risk of heart attack and stroke.
  • • Tonic: Garlic has a positive effect on the heart, stomach, lungs and spleen.
  • • Anti-infection: Externally, garlic can be used as a drawing poultice.
  • • Antiparasitic: Garlic has traditionally been used in enemas to rid the colon of intestinal parasites.
  • • Blood Purifier: Helps to stimulate the lymphatic system to more efficiently get rid of waste material.
  • • Glucose Control: Garlic has been found to be useful in controlling glucose tolerance and is beneficial for both hypo and hyperglycemia. Anyone with diabetes can benefit from garlic as well.
  • • Swelling: Garlic suppositories have been used to shrink hemorrhoids.
  • • Anti-inflammatory: The anti-inflammatory action of garlic makes it a valuable treatment for arthritis. Garlic reduces joint swelling and inflammation
  • • Antihypertensive: Garlic has been recognized by the Japanese Food and Drug Administration as an official treatment for high blood pressure.
  • • Garlic is a “wonder” food that is considered to be one of the most effective natural healing substances in the world.

    COMBINATIONS THAT ENHANCE GARLIC

  • • garlic, capsicum and vitamin C
  • • garlic, coenzyme Q10, carnitine, selenium and hawthorne berries
  • • garlic, ginseng, echinacea, and white willow
  • • garlic, horehound, echinacea, chickweed, mullein and licorice
  • • garlic, onion, raspberry leaves and licorice

    Garlic: Primary Applications

  • • asthma
  • • artherosclerosis
  • • arthritis
  • • blood clots
  • • blood pressure
  • • bronchitis
  • • Candida Albicans
  • • cardiovascular disease
  • • cancer prevention
  • • circulation
  • • colds
  • • colitis
  • • contagious diseases
  • • coughs
  • • ear infections
  • • digestion
  • • fever
  • • flu
  • • fungus
  • • gas
  • • heart disease
  • • hypertension
  • • infections (viral, bacterial and fungal)
  • • liver disorders
  • • parasites
  • • prostate gland
  • • respiratory diseases
  • • staph and strep infections
  • • yeast infections

    Garlic: Secondary Applications

  • • acne
  • • allergies
  • • arthritis
  • • diabetes
  • • diarrhea
  • • emphysema
  • • gallbladder
  • • hypoglycemia
  • • insomnia
  • • kidneys
  • • pneumonia
  • • rheumatism
  • • sinus
  • • ulcers
  • • warts
  • • worms

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    RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available
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    Date: June 24, 2005 05:34 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available

    The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.

    Bio-Aligned Antioxidant Support

    RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.

    Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.

    Healthy Heart

    Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.

    Nourishing the Brain

    Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.

    Liver Support

    Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.

    Immune Defense

    The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.

    Skin & Connective Tissue

    Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.

    Clear Vision

    Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.

    Energy Generation

    Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.

    DNA Protection

    DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.

    Living Longer, Living Better Strategies for Wellness

  • • Eat Well: Include plenty of fresh fruits and vegetables. Antioxidants in foods exist as vitamins C and E, beta-carotene, selenium and as flavonoids (tea), lycopene (tomatoes) and anthocyanins (berries). The highest concentrations of antioxidants are found in deeply colored fruits and vegetables such as dark leafy greens, artichokes, blueberries, cranberries, plums, blackberries and cherries. Spicing up food with cinnamon, turmeric, cloves and oregano can also boost antioxidant power.
  • • Stay Active: Exercise benefits the heart, helps regulate weight and slows the aging process by increasing the amount of oxygen available to body tissues.
  • • Reduce Stress: Deep breathing improves your blood’s oxygenation and circulation.
  • • Stop Smoking: Smoking depletes the body of vitamins C and E along with other antioxidants.

    Wellness Revolution

    Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.

    References

    Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.

    Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf

    Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein

    Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts

    Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric

    Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE

    Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc

    Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf



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    CLA and Ather osclerosis
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    Date: June 22, 2005 09:47 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CLA and Ather osclerosis

    CLA and Ather osclerosis

    CLA may well have benefits in the battle against heart disease as well. The leading cause of death in the United States is heart disease or related diseases of the circulatory system. Indeed, U.S. statistics show that about half the people in the United States die that way.

    In 1989, for example, some 2 million Americans died, and about 950,000 of those died as a direct or indirect result of heart disease. T h a t’s far more than the total number of deaths fro m AIDS, shootings, bombings and accidents combined.3 4 For pers p e c t i ve, let’s discuss what happens when a new s w o rthy accident o c c u r s — l e t’s say an airline crash that kills 200 people.

    Statistically speaking, five times that many people will die the same day of heart disease, as many as two each minute. Thankfully, doctors have made great progress in battling these conditions, and researchers have discovered that a healthy lifestyle can help the heart. Indeed, as almost everyone knows, balanced nutrition, lower stress and plenty of exercise can lead a person to be more healthy and to run a lower risk of heart attack and other heart conditions. Evidently, at least in animals, CLA seems to possess the ability to cut risks as well. Dr. Pariza and two colleagues, Kisun Lee and David Kritchevsky, studied a group of 12 rabbits that were fed a diet high in fat and cholesterol. They gave six of them CLA. In the academic journal Atherosclerosis, they reported that two dangerous compounds, LDL cholesterol and triglycerides, were “markedly lower” in the six that had diets supplemented with CLA.

    When the scientists looked at the aortas—the largest artery leading from the heart—of these animals, they also found a lot less blockage than in those that didn’t have CLA. This is how they summarized their results: “CLA appears to be hypocholesterolemic and anti-atherogenic.”35 This is pretty bold stuff for cautious scientists. Though the words are complex, the statement is clear: CLA seems to cut cholesterol and makes it so veins won’t clog as easily. This finding was surprising to Dr. Pariza. Science shows that straightened fatty acids (trans-fatty acids) of which CLA is one, usually tend to increase the risk of heart disease. Pariza said it only made sense to test CLA with this kind of science. Indeed, the best he would hope for would be no effect.36 In 1996, another group studied atherosclerosis and hamsters supplementing diets with CLA. CLA didn’t cut the amount of cholesterol in the blood within three months, but it did cut the amount of fatty build-up in the aorta of the hamsters.37 The bottom line on heart disease and CLA? Because two different types of animals show less clogging of the arteries, it seems clear that a good chance exists for the same thing to happen in humans. Of course, as with the cancer research, solid studies in humans need to be conducted for researchers to say definitely that this can cut your risk of heart disease. But until that day, the news is good: A nutritional regimen that includes solid antioxidants like vitamin C and vitamin A, that includes magnesium,38 coenzyme Q10,39 and that includes other important circulatory system-fortifiers would likely benefit from CLA. Couple that nutrition with a healthful lifestyle, and your chances of living longer and living better will likely increase.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=395)


    Pep Up and Go!
    TopPreviousNext

    Date: June 14, 2005 05:45 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Pep Up and Go!

    Pep Up and Go!

    by Harris Parker Energy Times, February 2, 2000

    Feel your energy flagging?

    You've lost count of the number of phone calls you fielded all afternoon-the last was from your son, who missed the late bus home from school-and colleagues needing your decision are lined up outside your office. Your husband has invited clients home for dinner. You wilt like a new hairdo on a damp August day and pray for a miracle to jump-start your engine.

    Your pep quotient depends on three essential ingredients: nutrients you consume through your diet and supplements, how much you exercise and your sleep schedule.(Of course, if you're troubled by any kind of disabling, ceaseless fatigue accompanied by mental fuzziness, joint pain, sore throat, swollen glands, headaches and other chronic distress, consult your health practitioner.)

    Vitamins and Energy

    Certain nutrients are called vitamins because scientists consider them to be crucial for vitality. They generally function as coenzymes, partnering with the enzymes that are catalysts for the chemical reactions constantly taking place in our bodies. Our need to replenish our store of vitamins, which may merge with cell, muscle, enzyme, hormone, blood and bone structure once they have been absorbed, depends on their rate of utilization, according to The Real Vitamin & Mineral Book (Avery) by Shari Lieberman, PhD, and Nancy Bruning.

    While a low-fat diet rich in raw fruits and vegetables helps supply important nutrients, a B complex supplement and a balanced multivitamin can guarantee daily vitamin levels.

    Be Energetic with B Vitamins

    Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. The chart on page 39 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their benefit is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).

    Vitamins B2 and B3, for example, supply the major building blocks for substances that are called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH), which are critical elements of energy production in the Krebs cycle as well as a process called oxidative phosphorylation.

    Hundreds of Reactions

    Even though you may never have heard of NAD and NADH, these molecules are found in very many places throughout your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.

    Energy to Spend

    The main energy currency of every cell single cell is ATP: a chemical called adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.

    Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy. (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)

    Making Energy

    The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.

    From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP.

    This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.

    Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.

    And Don't Overlook. . . . . .other supplements that may aid energy production: • Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors • Coenzyme Q10, also known as ubiquinone as it exists everywhere in the body, acts like a vitamin because it stimulates some reactions. CoQ10 protects cell membranes, especially of the heart, against oxidation and toxins.

    Ginsengs: Energy Generators

    With their legendary and slightly mysterious characteristics, the ginsengs are greatly respected natural energy boosters. " Perhaps no herb has excited so much interest in medical circles as ginseng, and yet, strangely, it does not actually 'cure' any one particular ailment," reports Michael Hallowell, the author of Herbal Healing (Avery) and a frequent lecturer on botanic medicine. "Rather, its virtue lies in its tremendous power as a tonic and invigorator. Russian athletes are prescribed large amounts of ginseng because researchers in Moscow have shown that it not only improves stamina, but also increases the efficiency with which blood is pumped to the muscles."

    What are the physiological mechanisms that allow ginseng to bolster your get up and go? In order to unravel the legend and lore of ginseng, the first step is understanding the intricacies of the three types: • Asian (Panax ginseng), which produces the strongest and most profound stimulation; • American (Panax quinquefolium), which soothes at a more subtle level; • Siberian (Eleutherococcus senticosus), a stamina booster embraced by a wide range of athletes. All three varieties are treasured for their ability to help people adjust to stress.

    Biologically Active

    The ginsengs are adaptogens, "biologically active substances found in certain herbs and plants that help the body and mind adapt to the changes and stress of life," says Stephen Fulder, MD, author of The Book of Ginseng and Other Chinese Herbs for Vitality (Inner Traditions). "Stress is not an illness in itself. Stress is change, our ability to adapt to all the changes that occur in life, emotional or physical, from exercise, work, chemicals, drugs, food, radiation, bacteria, disease, temperature, or simply too many late nights or too much fun."

    The body reacts to stress by producing the hormone adrenaline, which throws the whole body into a state of alert. Metabolism, blood pressure and circulation accelerate; immunity and resistance drastically decline; performance suffers.

    Top-Notch Tonics

    Enter the ginsengs, with their varied, subtle tonic qualities. The Greek name for this herb, "panax," means "panacea" or cure-all. But the Chinese, who first referred to it 2,000 years ago, more literally called it "ren shen" or "person root," in reference to its physical resemblance to a miniature human form.

    " Most exhibit medicinal properties, but each species has a different chemical makeup and has a unique application in Traditional Chinese Medicine (TCM)," says Kim Derek Pritts, author of Ginseng: How to Find, Grow and Use America's Forest Gold (Stackpole). "In general, all true ginseng contains biologically active saponins (chemicals similar to human hormones), essential oils, carbohydrates, sugars, organic acids, nitrogenous substances, amino acids, peptides, vitamins and minerals."

    Building Vital Energy

    All the ginsengs strengthen, nourish and build Qi, the TCM concept describing basic vital energy circulating through our bodies. Every physical and mental function, from breathing, thinking, nutrition and circulation, is regulated by Qi. Although many of the Native American tribes used the abundant, indigenous Panax quinquefolium ginseng extensively, particularly to increase mental acuity and boost fertility, the herb never has been as popular in North America as it is in Asia. American ginseng traditionally has been a lucrative export crop to China, where the wild native variety suffers from overharvesting. Even today, according to Paul Bergner in The Healing Power of Ginseng & the Tonic Herbs (Prima), 95% of the American ginseng crop is exported to China, where XiYang Shen, or "western sea root," as it is called, is immensely valued and costs double what it does here.

    Energy Boost

    Jacques MoraMarco, author of The Complete Ginseng Handbook: A Practical Guide for Energy, Health and Longevity (Contemporary), as well as a licensed acupuncturist and doctor of Eastern medicine, suggests American ginseng for a slight energy boost. The moderate effect of American ginseng is considered a more appropriate tonic to the intensity of our pace and diet.

    Variations on a Theme

    In TCM terms, American ginseng cools and moistens, as well as lubricates and strengthens the body. It is reputed to reduce fevers and night sweats and alleviate hot, dry lung problems like smoker's cough. With its emollient qualities, American ginseng is considered to treat dry, wrinkled skin effectively.

    The Bolder Energizer

    Asian ginseng, which includes red Korean panax, is a bolder energizer taken by those who feel depleted from anemia, blood loss, cardiovascular weakness, injury, shock or trauma, as well as the disabling effects of age. In general, Asian ginseng is warming and stimulating, urging the body to run faster.

    Siberian ginseng, though botanically not a true ginseng, still acts similarly to Asian ginseng in its reputed power to control stress, boost energy, support the immune system, enhance performance and increase longevity. Called Wu Cha Seng in Chinese, Siberian ginseng is perceived by natural practitioners as an ideal herb for the healthy who want to lift both stamina and endurance. Experts believe it counteracts the effects of cortisol, the stress hormone produced by the adrenal glands in response to injury, pain or emotional turmoil.

    Natural Energy Boosters

    The herbal pharmacopeia includes several other natural energy boosters available in various forms-shakes and bars for those on the run-loaded with nutrition absent from commercial snacks. Some choices: • Ginkgo biloba-used in Chinese medicine to heat the body and increase sexual energy. Ginkgo enthusiasts take this herb to increase the supply of oxygen to the brain and generally increase circulation. • Gotu kola-may stimulate the central nervous system and help eliminate excess fluid, thereby reducing fatigue. • Astragalus-a Chinese herb that enhances energy and builds the immune system. It is credited with strengthening digestion, improving metabolism, increasing appetite, combating diarrhea and healing sores. • Schisandra-also a Chinese herb, treats respiratory illness, insomnia and irritability and rejuvenates sexual energy. Its mild adaptogens help the body to handle stress. • Licorice-is a favored endocrine toner in Chinese medicine. It is reputed to support the adrenals, the pair of small glands directly above the kidneys that secrete steroidal hormones, norepinephrine and epinephrine, the "fight or flight" hormones. People with high blood pressure or edema, or pregnant women, should avoid it. • Ashwagandha-an Ayurvedic herb used for thousands of years in the traditional healing of India as a potent strength builder for men and women.

    Experienced herbal practitioners acquire an impressive and fascinating store of knowledge and experience-you'll find it helpful to visit one as you begin your course of ginseng or other energy-boosting herbs.

    TCM Visitation

    When you visit a TCM practitioner, you'll notice that she evaluates your body's condition through an extremely careful examination of all the different systems: Several pulse points are felt in order to ferret out and detect troubling abnormalities. The condition and color of the tongue is observed to decipher digestive disorders. In addition, your urine may be examined to determine other imbalances and specific health problems.

    In many cases, your TCM practitioner will recommend ginseng as an adaptogen that can give you an overall boost. When taking ginseng, follow the directions on the package. Note: in some cases, you may want to consume a little bit less if you suffer headaches, insomnia or high blood pressure. Consult your health practitioner if you are afflicted with either acute inflammatory disease or bronchitis.

    Then take comfort in the eternal soothing wisdom of Chinese Traditional Medicine. In the first century A.D., the Shen Nong Ben Cao Jing (The Divine Husbandman's Classic of the Materia Medica) effusively described ginseng and the tonic herbs in this beguiling and intriguing manner: "The first class of drugs...are considered to perform the work of sovereigns. They support human life and they resemble heaven. They are not poisonous regardless of the quality and duration of administration."



    --
    Vitanet ®

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=353)


    Energy Vitamins
    TopPreviousNext

    Date: June 11, 2005 05:50 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Energy Vitamins

    Energy Vitamins by Daniel Mowrey, PhD Energy Times, June 7, 1998

    Do you suffer groggy mornings clouded with tired and achy feelings? Do you have to struggle to muster sufficient energy to cope with the day? Then, throughout the morning and afternoon, does frequent fatigue, weakness or depression persist on your horizon like an ugly storm cloud? And your evening may bring little relief as you slump into bed for a restless night, only to begin the same routine the next morning. If lack of vim and vigor plagues your days and nights, your body may be suffering from an inability to synthesize sufficient energy.

    Our lives depend on processing the food we eat into substances our cells can take in and use. In a never-ending cycle, our body breaks food down and reconstructs the components to form body structures and burn as energy.

    How much you exercise, the food and supplements you eat and how much you sleep influence the efficiency of these processes.

    Vitamins and Energy

    Certain nutrients are called vitamins because they are crucial for vitality. These nutrients are essential to a productive life, the starting point for all life-giving and life-sustaining processes. Because of vitamins' crucial role in energy production, many people can perk up their stamina simply by consuming an adequate supply of vitamins in their daily diet. Since many vitamins - especially the ones concerned with energy - must be constantly replenished, a decent diet and the right supplements must be consumed every day.

    Be Energetic with B Vitamins

    Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. Their most important roles are shown in the illustration on page 48. The chart on page 46 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their effect is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).

    Vitamins B2 and B3, for example, supply the major building blocks for substances called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH) which are critical elements of producing energy in the Krebs cycle as well as a process called oxidative phosphorylation.

    Even though you may never have heard of NAD and NADH, these molecules are found in many places in your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.

    Energy to Spend

    The main energy currency of every cell is ATP: adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.

    Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)

    Making Energy

    The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.

    From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP. This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.

    Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.

    Get Your Vitamins Every Day

    While we rely on our diet to supply many of our vitamins, a B complex supplement and multi-vitamins can ensure you consume sufficient amounts of these crucial nutrients.

    Many experts agree that a diet rich in raw fruits, nuts and vegetables that minimizes saturated fat can supply adequate a-mounts of these nutrients. Other supplements that may aid energy production:

    Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors. CoQ10, a nutrient that protects cell membranes, especially of the heart, against oxidation and toxins. Plus, herbs such as suma, ginseng and licorice root as well as creatine, carnitine and pyruvate.

    Of course if you suffer from any long term, intractable fatigue, consult your health practitioner. But for most cases of decreased vim and vigor, adequate vitamins should help your body recover your get up and go.



    --
    Vitanet ®

    Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=299)



    TopPreviousNext

    Date: June 09, 2005 05:36 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    Energy Vitamins by Daniel Mowrey, PhD Energy Times, June 7, 1998

    Do you suffer groggy mornings clouded with tired and achy feelings? Do you have to struggle to muster sufficient energy to cope with the day? Then, throughout the morning and afternoon, does frequent fatigue, weakness or depression persist on your horizon like an ugly storm cloud? And your evening may bring little relief as you slump into bed for a restless night, only to begin the same routine the next morning. If lack of vim and vigor plagues your days and nights, your body may be suffering from an inability to synthesize sufficient energy.

    Our lives depend on processing the food we eat into substances our cells can take in and use. In a never-ending cycle, our body breaks food down and reconstructs the components to form body structures and burn as energy.

    How much you exercise, the food and supplements you eat and how much you sleep influence the efficiency of these processes.

    Vitamins and Energy
    Certain nutrients are called vitamins because they are crucial for vitality. These nutrients are essential to a productive life, the starting point for all life-giving and life-sustaining processes. Because of vitamins' crucial role in energy production, many people can perk up their stamina simply by consuming an adequate supply of vitamins in their daily diet. Since many vitamins - especially the ones concerned with energy - must be constantly replenished, a decent diet and the right supplements must be consumed every day.

    Be Energetic with B Vitamins
    Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. Their most important roles are shown in the illustration on page 48. The chart on page 46 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their effect is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).

    Vitamins B2 and B3, for example, supply the major building blocks for substances called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH) which are critical elements of producing energy in the Krebs cycle as well as a process called oxidative phosphorylation.

    Even though you may never have heard of NAD and NADH, these molecules are found in many places in your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.

    Energy to Spend
    The main energy currency of every cell is ATP: adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.

    Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)

    Making Energy
    The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.

    From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP. This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.

    Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.

    Get Your Vitamins Every Day While we rely on our diet to supply many of our vitamins, a B complex supplement and multi-vitamins can ensure you consume sufficient amounts of these crucial nutrients.

    Many experts agree that a diet rich in raw fruits, nuts and vegetables that minimizes saturated fat can supply adequate a-mounts of these nutrients. Other supplements that may aid energy production:

    Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors. CoQ10, a nutrient that protects cell membranes, especially of the heart, against oxidation and toxins. Plus, herbs such as suma, ginseng and licorice root as well as creatine, carnitine and pyruvate.

    Of course if you suffer from any long term, intractable fatigue, consult your health practitioner. But for most cases of decreased vim and vigor, adequate vitamins should help your body recover your get up and go.



    --
    VitaNet ®
    VitaNEt ® Staff

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=260)


    Skin Eternal - Replenish Your Skin
    TopPreviousNext

    Date: June 06, 2005 08:45 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Skin Eternal - Replenish Your Skin

    Skin Eternal

    Source Naturals is proud to introduce our new SKIN ETERNAL Cosmetic Line. Our advanced skin care products recharge and revitalize your skin. Each product features scientifically advanced nutraceuticals: nutrients and botanicals with an inborn affinity for skin. You can nourish your skin with Source Naturals’ richly emollient SKIN ETERNAL CREAM smoothed under your eyes or on your neck. Or use our light, aqueous SKIN ETERNAL SERUM. Both products gently addresses imbalances and infuse skin with visible radiance. For a luxuriant, moisturizing bath, simply add SKIN ETERNAL BATH OIL under warm running water. Whatever your individual preference, Source Naturals has a SKIN ETERNAL product that will leave your skin looking refreshed and energized.

    Now available from Source Naturals®: a variety of elegant cosmetics to moisturize, smooth and tone your skin.

    Your skin is a reflection of your health and well-being. To attain skin that looks truly alive, energized and refreshed, we believe a holistic approach is necessary. This includes nourishing your body with fresh, organic foods, exercising every day to motivate your mind and spirit, and eliminating unhealthy lifestyle choices. As part of this holistic approach, the Skin Eternal™ cosmetic line feeds your skin cells with scientifically advanced nutraceuticals: nutrients and botanicals with an inborn affinity for skin.

    SKIN ETERNAL™ CREAM

    Apply this rich and luxurious blend under and around your eyes or massage it with upward strokes onto your neck—your skin will immediately feel the difference! SKIN ETERNAL CREAM features nutrients, natural oils and plant extracts. Included are alpha lipoic acid, biotin, CoQ10, DMAE, jojoba oil, MSM, squalane, tocotrienols, and vitamin C-ester, as well as extracts of grape seed, ginkgo, ginseng, green tea, sage, marigold, and grapefruit seed.

    SKIN ETERNAL™ SERUM

    SKIN ETERNAL SERUM is an aqueous moisturizing serum that contains a rich blend of nutrients and plant extracts. It is easily absorbed, and immediately makes skin feel softer and replenished. SKIN ETERNAL SERUM is lightly scented with pure lavender and lemon oils, and contains nutrients and herbs unavailable in other topical preparations. These include aloe vera, alpha lipoic acid, biotin, CoQ10, DMAE, MSM, vitamins A, C-ester, D-3 and E, and chamomile. Source Naturals also offers SKIN ETERNAL DMAE SERUM.

    SKIN ETERNAL™ BATH OIL

    OUR NEW SKIN ETERNAL BATH OIL adds to your skin’s hydrolipic film, lightly coating your skin with nutrients. It holds moisture inside and protects your skin. Its unique formula is rich in alpha lipoic acid, DMAE, essential fatty acids, vitamins C-ester and E, plus other nutrients and plant extracts. SKIN ETERNAL BATH OIL is lightly scented with pure lavender and lemon oils. And it is hypoallergenic and contains no alpha hydroxy acids—so it can be used even on delicate, sensitive skin.

    Lifestyle Tips for Healthy Skin: A Strategy for WellnessSM

    Eat a Healthy Diet Low-nutrient foods, such as sugar and refined carbohydrates, will not provide the vitamins and minerals your skin needs. Choose unprocessed organic foods, high in antioxidants such as beta carotene (carrots, apricots, and squash), vitamin C (oranges and peppers), vitamin E (cold-pressed oils, nuts and seeds), selenium (tuna, garlic, onions and broccoli) and zinc (whole grains, most seafood, and onions). Essential fatty acids, such as those in oily fish, flaxseed and olive oil, are important for skin repair. Eat high-fiber fruits, vegetables, whole grain bread and cereals, and brown rice. Restrict excess sodium intake.

    Take Supplements

    Key nutraceuticals can help radiate beauty from within, by supporting body systems involved with healthy, radiant skin. These nutraceuticals include alpha lipoic acid, DMAE, ascorbyl palmitate (vitamin C-ester), vitamin E and grapeseed extract. Source Naturals offers you SKIN ETERNAL™ tablets with these five ingredients, to protect against free radical damage and provide cofactors for healthy skin tissue. Source Naturals SKIN ETERNAL PLUS is a Bio-Aligned Formula™, which includes these key nutraceuticals plus 30 more! It is designed to support multiple body systems: antioxidant defense, connective tissue, cell membranes, cell renewal, blood and liver cleansing, muscle and nerve function, and stress response. It is also useful to supplement with essential fatty acids, such as omega-3 and omega-6 fatty acids, flaxseed and primrose oil.

    Drink Water

    Our bodies are made up of 50-70% water, so it’s important to drink at least 1.5 liters daily. Water flushes out wastes, and acts as an internal moisturizer, keeping skin hydrated and supple. Spring water is beneficial since it contains trace minerals vital to healthy skin.

    Protect Your Skin from the Sun

    Avoid direct sun from 10 am to 4 pm, when ultraviolet radiation is strongest. Use sunscreen even during winter and on cloudy days. Wear a broad-brimmed hat and sunglasses with full UV protection.

    Get Plenty of Sleep

    Research has shown that skin regenerates itself between 1-3 am; lack of sleep during those hours can cause skin to look dull or puffy. Taking a melatonin supplement can be helpful in supporting your body’s normal sleep cycle.

    Exercise Regularly

    Exercise increases circulation, which delivers nutrients necessary for a clear, glowing complexion. It also burns off fat, helps eliminate toxins, and is a great stress reliever. Exercise three to five times a week until you are perspiring freely and breathing deeply.

    Avoid Excessive Alcohol and Coffee

    Alcohol weakens the immune system and depletes nutrients. It causes dehydration, depriving skin of moisture, and overtaxes the liver, which helps keep impurities from reaching other organs. Alcohol consumption can lead to broken or distended capillaries, especially over the nose and cheeks. Caffeine-rich beverages like coffee promote dehydration, leaving skin flaky and dry. Substitute herbal or green tea for coffee.

    Stop Smoking

    Smoking slows healing and regeneration, causes carbon monoxide to increase in blood, and induces free radical formation. Nicotine constricts blood vessels and reduces blood flow to skin. The benzopyrene in cigarette smoke inhibits absorption of vitamin C, which is important for collagen synthesis.



    --
    VitaNEt ®
    VitaNet ® Staff

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=195)


    Red Yeast Rice For Lipid Wellness
    TopPreviousNext

    Date: June 04, 2005 02:30 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Red Yeast Rice For Lipid Wellness

    Red Yeast Rice

    Maintaining cardiovascular health is a fundamental strategy in the holistic healing system. It may be the most important thing you can do for your body. One of the factors for optimal cardiovascular health is keeping your lipid levels within the normal range. But with today’s fast-paced lifestyle, it’s hard to maintain a healthy diet and exercise program. Red yeast rice is a natural product that supports maintenance of normal lipid levels. Source Naturals RED YEAST RICE is standardized to 1.5% mixed mevinolinic acid monacolins. These monacolins block the synthesis of lipids in the liver by binding to the lipids production enzyme HMG-CoA reductase. Support your lipid wellness with the quality and science of Source Naturals RED YEAST RICE.

    The Liver and Lipid

    The amount of lipid you consume in food is not the most important factor for regulating normal lipid levels. The liver manufactures approximately 80% of total body lipid while the other 20% comes from dietary sources. Our bodies require lipid but we can also get too much of it. Lipid is only harmful to us if it becomes oxidized. Oxidized lipid can cause damage to tissues and accumulate in blood vessels. Balancing the lipid produced by your liver is critical to your total lipid and your cardiovascular health.

    Red Yeast Rice

    Red yeast rice has been used in China for centuries to make rice wine, to color and flavor foods such as Peking duck and as a health promoting food. It is prepared by fermenting a type of yeast (Monascus purpureus) over rice. Red yeast rice is a complex product that contains several active ingredients including monacolins. Monacolins act as HMG-CoA inhibitors. HMG-CoA reductase is an enzyme that helps make lipid. By blocking its lipid producing action, the natural compounds in red yeast rice can help you maintain lipid levels that are within the normal range. A double blind clinical trial using red yeast rice and placebo with 80 human subjects was conducted at UCLA. After eight weeks with no changes in diet composition the group taking red yeast rice maintained healthy lipid levels.

    Natural Support For Your Heart

    Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Taking personal responsibility for your health is at the heart of the wellness revolution. Changing your lifestyle is one of the most effective ways to take that responsibility and provide support and protection for your heart. A diet low in lipid, saturated fats and trans-fatty acids, and high in complex carbohydrates and fiber is important. Exercise regularly, quit smoking and supplement your diet with heart-healthy compounds such as red yeast rice, CoQ10, folic acid, garlic, omega-3 fatty acids, carnitine, hawthorn berry extract, arginine, vitamin E and tocotrienols. Source Naturals RED YEAST RICE is standardized to 1.5% mixed mevinolinic acid monacolins. This standardization process provides you with the assurance that you are getting a consistent concentration of these compounds in each dose. RED YEAST RICE is part of Source Natural’s extensive line of products scientifically formulated to provide support for your cardiovascular health.

    References:
    Heber, David. Lipid-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. American Journal of Clinical Nutrition 1999: 69(2):231-236. Zhu Y, Li CL, Wang YY, Zhu JS, Chang J, Kritchevsky D. Monascus purpureus (red yeast): a natural product that lowers blood lipid in animal models of hyperlipidemia. Nutr Res 1998; 18:71-81. Medical Encyclopedia. Medlineplus Health Information [online]. U.S. National Library of Medicine and the National Institutes of Health, 2003 [October 22, 2003]. Available from World Wide Web: edlineplus/ encyclopedia.html.



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    Menopause Multiple - Eternal Woman
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    Date: June 03, 2005 05:54 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Menopause Multiple - Eternal Woman

    Menopause

    Menopause happens to all women, but affects each woman uniquely. For some, the end of fertility (and the end of concerns about contraception) brings a sense of freedom. For others, it is a time of troublesome symptoms or perhaps the need for certain lifestyle adjustments. Menopause is a bridge to a point in life when many women report feeling more confident, empowered and energized than in their younger years. MENOPAUSE MULTIPLE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems: hormonal regulation, bone metabolism, cardiovascular health, energy generation and circulation.

    After menopause, the ovaries no longer secrete two critical steroid hormones in the amount or pattern characteristic of a regular menstrual cycle. These two hormones are estrogen and progesterone. The transition from regular ovarian function to its absence is often called the perimenopause or perimenopausal transition. The time involved can range from one to 10 years. More than one third of the women in the United States, about 36 million, have been through menopause. With a life expectancy of 81 years, a 50-year-old woman can expect to live more than one third of her life after menopause. Low estrogen levels are linked to some uncomfortable symptoms in many women. The most common and easy to recognize symptom is hot flashes -- sudden intense waves of heat and sweating. Some women find that these hot flashes disrupt their sleep, and others report mood changes. Other symptoms may include irregular periods, vaginal or urinary tract infections, urinary incontinence (leakage of urine or inability to control urine flow), and inflammation of the vagina. Because of the changes in the urinary tract and vagina, some women may have discomfort or pain during sexual intercourse. Many women also notice changes in their skin, digestive tract, and hair during menopause. Because the menopausal years place unique nutritional demands on a woman’s body, Source Naturals created MENOPAUSEMULTIPLE. This comprehensive formula brings together optimal amounts of the finest phytonutrients and herbs--including genistein, black cohosh, and chaste berry--plus vitamins and minerals known to support the biochemistry of mature women.

    Bio-Aligned Formula™

    MENOPAUSE MULTIPLE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with female hormone function.

    Hormonal Regulation

    Hot flashes are related to hormone levels. As estrogen declines, FSH and LH (folliclestimulating and luteinizing hormones) increase, causing blood capillaries to dilate. This brings more blood and higher temperatures to the skin. Soy isoflavones and other herbs can mimic the effects of estrogen. Support for the adrenal glands is important since they account for most estrogen production after menopause.

    Musculoskeletal System

    During and after menopause, a woman’s hormonal balance and biochemistry change. Lower estrogen levels may affect bone density. Phytonutrients and calcium are important to maintain healthy bones in postmenopausal women. Calcium and magnesium work together in the metabolism of bone.

    Heart & Circulation

    Menopause increases concern for the health of the heart and circulatory system. Soy isoflavones and other ingredients may help maintain healthy cholesterol levels. To regulate homocysteine levels for cardiovascular health, vitamins B-6, B-12, and folic acid are critical.

    Liver Support

    Among its many functions, the liver has the important job of promoting hormonal balance by processing excess levels of hormones. The powerful antioxidant, N-acetyl cysteine, helps the liver detoxify chemicals and milk thistle is a liver protectant.

    Energy Generation

    The fatigue that is common during menopause makes nutritional support for energy and metabolism especially important. Metabolism can influence weight, energy levels, and mood. MENOPAUSE MULTIPLE contains ingredients that support energy generation, including the advanced nutrients CoQ10 and lipoic acid and ginkgo biloba.

    Antioxidants: Anti-Aging

    Antioxidants help protect the circulatory system, which is important as estrogen declines. Antioxidants also defend tissues and cell membranes in all your body systems from free radicals, which are formed during normal cellular metabolism. Some important antioxidants: vitamin E, vitamin C, selenium, zinc, and manganese all have strong antioxidant powers.

    Lifestyle Tips for a Healthy Transition

    Get Moving. Exercise is a powerful remedy for many menopause complaints and may help prevent future menopause-related diseases. It promotes better, more restorative sleep, and it stimulates production of endorphins, or “feel good” brain chemistry. Some women report having fewer hot flashes when they exercise regularly. Eat Well. A balanced diet low in saturated fat and high in whole grains, fruits and vegetables, with adequate water, vitamins and minerals contributes to good health. Women at perimenopause and beyond have special dietary concerns, because both heart disease and osteoporosis are greatly affected by diet. A balanced diet is also important for bone development and maintaining bone strength. Some women – especially those who are elderly and have reduced appetites, who diet frequently, who don’t consume diary products, or who have eating disorders – may not consume adequate vitamins and minerals to maintain optimal bone mass. There is evidence that the natural, estrogenlike compounds in soybeans and many other plant foods used in MENOPAUSE MULTIPLE may reduce hot flashes and vaginal dryness and increase bone density in women after menopause. Studies suggest that body cells respond to plant estrogens as if they were weaker versions of the human hormone. So consuming more of these estrogen-mimicking compounds may help compensate for the loss of estrogen naturally as women age. Prevent Bone Loss. Osteoporosis is one of the most preventable of bone diseases. Exercise maintains the strength of bones through aerobics, stair climbing, hiking, or walking. Prevention focuses on nutrition for bones, including a sufficient calcium intake of 1000 to 1500 mg/day.

    Musculoskeletal System: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Boron, Calcium, Magnesium, Manganese, Vitamins A, B-6, B-12, C, D & E, Folic Acid

    Heart and Circulation: Black Cohosh, Coenzyme Q10, Dong Quai, Licorice, Soy Isoflavones, Magnesium, Vitamins B-6, B-12, & E, Folic Acid

    Hormonal Regulation: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Vitex, Vitamins B-5 & C

    Liver Support: Coenzyme Q10, N-Acetyl Cysteine, Dandelion, alpha-Lipoic Acid, Silymarin, Selenium, Vitamin C, Biotin

    Antioxidant Defense: Coenzyme Q10, N-Acetyl Cysteine, alpha-Lipoic Acid, Silymarin, Selenium, Zinc, Vitamins A, C & E

    Energy Generation: alpha-Lipoic Acid, Coenzyme Q10, Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-5, & B-6, Niacinamide

    References
    Abraham, G.E. & Grewal, H.G. 1990. JRM, 35:503. Anderson, J.W., et al. 1995. The New England Journal of Medicine, 335(5): 276-82. Avioli, L. V. (1993). Calcium and Bone: Myths, Facts and Controversies in the Osteoporotic Syndrome: Detection, Prevention and Treatment, 3rd ed. (Avioli ed.) New York: Wiley-Liss. Christy, C.J. 1945. American Journal of Obstetrics & Gynecology, 50:45. Colborn, Theo. 1996. Our Stolen Future. New York: Dutton. Murkies, A.L., et al. 1995. Maturitas, 21:189-95. Nielsen, F.H., et al. 1987. FASEB J, 1:394-97. Raines, E.W., & Ross, R. 1995. Journal of Nutrition, 125:624S-30S. Tranquilli, A., et al. 1994. Gynecological Endocrinology, 8(1):55-8.



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    NutraSpray in Melatonin, Proanthodyn, and St. John's wort
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    Date: June 03, 2005 05:35 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: NutraSpray in Melatonin, Proanthodyn, and St. John's wort

    NutraSpray

    NUTRASPRAY represents a quantum leap in the evolution of supplementation, an elegant combination of convenience, fast action, bioavailability, and sustained release delivery. Source Naturals has long championed the sublingual delivery system, and our Super Sublingual™ is the latest step in the science of nutrition. A quick spritz of NUTRASPRAY under the tongue delivers thousands of microscopic lipid spheres, each full of nutrients. These lipospheres are readily absorbed and retained by the mucosal tissue of the mouth. Here they release their nutrients quickly, but steadily, into the bloodstream – creating a Super Sublingual, the most bioavailable supplement today.

    Nutrient delivery systems include tablets, capsules, softgels, and liquid extracts. Their purpose is to ensure the cells in your body get the nutrients they need from the supplements you take. Sublinguals bypass the digestive system – and its potentially destructive juices – by dissolving under the tongue to be directly absorbed into the bloodstream. Tests show that the NUTRASPRAY liposome sublingual delivery system is more efficient than traditional sublinguals.

    The First Timed Release Sublingual

    Due to the multi-layered structure of the tiny lipospheres, nutrients are gradually released for extended periods of time, maintaining optimal dosage throughout the day or night. This combined with a faster onset of the active ingredients – usually within 15 minutes – makes NUTRASPRAY the most bioavailable delivery system for nutritional supplements today, and the first truly timed release sublingual.

    Unparalleled Convenience

    NUTRASPRAY incorporates a simple, non-aerosol spray pump that’s easily carried in purse or pocket. Its modern functional design is a perfect complement to today’s active lifestyle. It’s easy to regulate nutrient amount, because the convenient pump delivers a specific amount of nutrient-rich liposomes with every spray, and each 2 fl. oz. recyclable plastic bottle can deliver 80 full sprays. Stevia is added as an ingredient in each NUTRASPRAY product.

    Advanced Research

    The lipid micro-encapsulation process is based on years of research in liposomal technology. The result is NUTRASPRAY, a proprietary system to deliver nutrients in the most efficient manner. This sublingual oral spray is a liquid suspension of liposomes, which are nutrients encased in very complex microscopic lipid spheres, 1/50th the diameter of a human hair. A highly purified natural lecithin forms the membrane of these lipid spheres, which are able to move easily through the lipid environment surrounding the capillaries in the mouth. Lipospheres then gradually release their nutrients into bloodstream.

    Nutrients That Go To Your Head

    The Source Naturals NUTRASPRAY line includes natural supplements that are particularly well-suited to this Super Sublingual delivery system, such as Melatonin, Ginkgo Biloba, Coenzyme Q10, Grape Seed extract, and Kava. That’s because these nutrients need to reach the brain for maximum benefit. Also, they’re usually taken for reasons that the fast-acting quality of NUTRASPRAY satisfies. Another unique reason NUTRASPRAY is so bioavailable is that its nutrients bypass the liver on their first pass through the circulatory system. This ensures the nutrient is available to the brain for maximum potency. Source Naturals NUTRASPRAY MELATONIN delivers 1.5 mg of the finest quality Melatonin with each full spray, easily allowing customers to control their intake. Melatonin is ideally suited to the fast-acting nature of NUTRASPRAY, which maintains a more balanced release of Melatonin throughout the night. Source Naturals NutraSpray GINKGO-24™ provides 60 mg of Ginkgo Biloba per full spray. This makes Ginkgo’s beneficial constituents readily available to the capillaries in the blood-brain barrier, facilitating oxygen flow to the brain. CoQ10 is fat soluble; therefore encapsulating it in a lipid is the perfect way to ensure its bioavailability. Each full spray of Source Naturals NUTRASPRAY™ COQ10 yields 30 mg of CoQ10. Furthermore, this popular metabolic enhancer is very experiential with the NUTRASPRAY delivery system. NUTRASPRAY GRAPE SEED extract delivers 50 mg per spray of proanthocyanidins standardized to 95%. These highly bioavailable flavonoids are able to cross the blood-brain barrier, offering potent antioxidant protection to precious neurons. NUTRASPRAY KAVA KAVA is a potent extract standardized to a potent 40% kavalactones, the active constituents of this traditional root from the Polynesian cultures of the South Pacific. The relaxing action of Kava works through the brain’s limbic system, which regulates emotions related to survival issues, including the “fight or flight” response. Each spray yields 60 mg of Kava. Look for other fine products soon to come out in the Source Naturals line of NUTRASPRAYS. Source Naturals built its reputation on bringing the latest nutritional research to market, using the finest ingredients in substantial quantities – for an experience of wellness and vitality you can feel. Source Naturals NUTRASPRAY is a major step toward empowering people to achieve optimal health in a challenging world.



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    Joint Response and Ultra Joint Response
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    Date: June 02, 2005 01:01 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Joint Response and Ultra Joint Response

    Many people are unaware of the multiple body systems involved with joint health. Source Naturals ULTRA JOINT RESPONSE™ is a Bio-Aligned Formula™ that goes deep to bring alignment to these multiple systems. It features structural building blocks, tissue production cofactors, and ingredients that aid the body’s mechanisms for soothing relief and antioxidant defense.

    Joint Support Formulations

    You can use ULTRA JOINT RESPONSE alone or as the core of your healthy joints program, complementing it with additional potencies and ingredients. These include: GLUCOSAMINE CHONDROITIN WITH MSM™, MSM Cream, SAME, CM COMPLEX™ Cetyl Myristoleate, and BROMELAIN. For muscle discomfort and fatigue, Source Naturals also offers you FIBRO-RESPONSE™ Bio-Aligned Formula.

    ULTRA JOINT RESPONSE™: BIO-ALIGNED FORMULA

    ULTRA JOINT RESPONSE uses scientifically researched ingredients and nutritive co-factors for a comprehensive approach to soothing, lubricating, rebuilding and aligning connective tissue, joints, tendons and ligaments. MSM dietary sulfur, glucosamine and sea cucumber provide structural building blocks that are necessary to help maintain the integrity of joints and connective tissue. Vitamins A, B-6 and C, zinc, manganese, and copper act as co-factors or parts of enzymes that play a role in connective tissue formation and maintenance. Various soothing herbs, rich in polysaccharides and other constituents, assist the body’s natural mechanisms for soothing relief. Finally, N-acetyl cysteine, grape seed, beta carotene, vitamin C, zinc, selenium, horse chestnut, turmeric, and quercetin support the body’s natural antioxidant response, thereby helping maintain the health and integrity of joints and tissues (specifically cell membranes).

    GLUCOSAMINE CHONDROITIN WITH MSM: HOT RESEARCHED INGREDIENTS

    For added support, Source Naturals offers you a formula that combines higher potencies of the most popular joint nutrients: glucosamine sulfate, chondroitin sulfate and MSM. GLUCOSAMINE CHONDROITIN COMPLEX WITH MSM provides the same amounts of chondroitin and glucosamine shown in recent research to support healthy joints—along with MSM, vitamin C, and molybdenum, for a more powerful product. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement.

    FIBRO-RESPONSE: BIO-ALIGNED FORMULA Dealing with the muscle discomfort that affects millions in our society requires more than alleviating fatigue. FIBRO-RESPONSE influences specific body systems and tissues involved in joint health and muscular metabolism. Malic acid and magnesium, supplied in the same amounts used in recent research, help support muscular energy production, along with coenzyme Q10, lipoic acid and B-complex vitamins. MSM, copper, manganese, molybdenum, zinc, vitamin C, and beta carotene support healthy connective tissue, which is essential for proper joint and muscle function. Key ingredients, including N-acetyl cysteine and silymarin aid the liver in eliminating toxic waste from blood and tissues. Ingredients including lipoic acid, selenium, N-acetyl cysteine, and coenzyme Q10 support antioxidant defense, thereby helping to maintain tissue integrity. And ginkgo and GABA are among the ingredients that support clear focus and stress reduction.

    LIFESTYLE TIPS FOR HEALTHY JOINTS: A STRATEGY FOR WELLNESSSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, and eliminate polyunsaturated and hydrogenated oils. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: In addition to the formulas described above, Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAMe, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CM COMPLEX™ Cetyl Myristoleate, a fatty acid ester shown in recent research to reduce joint discomfort.



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    Heart Science - A Five-Tiered Approach to Heart Health ...
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    Date: June 02, 2005 12:07 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

    Heart Science 30 tabs

    Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

    Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

    Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
    1) generating energy,
    2) decreasing harmful homocysteine levels,
    3) fighting oxidized cholesterol,
    4) maintaining the heart’s electrical rhythm, and
    5) protecting artery and capillary linings.

    Energy Generators for An Energetic Organ

    Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

    There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

    CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

    Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

    Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

    HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

    Homocysteine Regulators

    B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

    The Dangers of Oxidized LDL Cholesterol

    While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

    When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

    The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

    Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

    Cholesterol Fighters

    Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

  • • Beta Carotene, a plant pigment, is the naturally occurring precursor to Vitamin A. When the body takes in high enough amounts of Beta Carotene, this lipid-soluble free radical scavenger concentrates in circulating lipoproteins and atherosclerotic plaques, where it performs its antioxidant functions. Beta Carotene is particularly unique and powerful as an antioxidant because it is capable of trapping a very toxic form of di-oxygen, called singlet oxygen, which can result in severe tissue damage. Beta Carotene is one of the most efficient quenchers of singlet oxygen thus far discovered. Six tablets of HEART SCIENCE provide an unprecedented 45,000 IU of Beta Carotene!
  • • Vitamin C is found in plasma, the watery component of blood, where it functions as a potent antioxidant. In addition to strengthening artery linings through collagen manufacture, Vitamin C is involved in the regeneration of Vitamin E within LDL particles. Vitamin C also plays an important role in the conversion of cholesterol into bile acids by the liver, a crucial step in reducing blood cholesterol levels. Once converted into bile acids, and then into bile salts, cholesterol can be excreted from the body, preventing build-up. Supplementation with Vitamin C may lower levels of LDL cholesterol and increase those of HDL cholesterol.25 It may also have a part in actually removing cholesterol deposits from artery walls — good news for people who are already experiencing plaque buildup.25 Each daily dose of HEART SCIENCE provides 1,500 mg of Vitamin C in its bioactive mineral ascorbate form.
  • • Vitamin E, together with Beta Carotene, protects lipids from free radical attack. It is the major antioxidant vitamin that is carried in the lipid fraction of the LDL particle, where it protects the LDL particle from damaging oxidation. Within an LDL particle, one molecule of Vitamin E has the ability to protect about 200 molecules of polyunsaturated fatty acids from free radical damage! Vitamin E also aids in protecting the heart by interfering with the abnormal clumping of blood cell fragments, called platelets, within blood vessels.4 It has been shown to inhibit the formation of thromboxanes and increase the production of prostacyclins, which together decrease abnormal platelet aggregation.11 A high potency of Vitamin E — 400 IU’s — is included in six tablets of HEART SCIENCE in the natural d-alpha succinate form, recognized by scientific researchers to be the most absorbable form!
  • • Selenium is an important mineral which has only recently gained attention. When incorporated into the enzyme Glutathione Peroxidase, it has highly powerful free radical-scavenging abilities, and has been shown to work synergistically with Vitamins A, C, and E. An essential mineral, Selenium used to be derived from eating foods grown in Selenium-rich soil. However, modern agricultural practices have depleted soil of its natural Selenium content, leaving many Americans deficient in this vital nutrient. Several epidemiological studies show that the incidence of advanced fatty deposits in blood vessels is much greater in individuals living in geographic areas of the United States and other parts of the world where the Selenium content of the soil is very low.27
  • Proanthodyn,™ an extract of grape seeds, is being called the most powerful antioxidant yet discovered. This highly potent, water-soluble bioflavonoid contains between 93-95% proanthocyanidins, the highest concentration of any nutrient available today. The protective actions of proanthocyanidins may help to prevent the development of plaque in artery walls by inhibiting the free radicals which are produced during the oxidation of cholesterol. The optimal daily amount (100 mg) of Proanthodyn is included in six tablets of HEART SCIENCE. In addition to the protective actions of antioxidants, several other nutrients can contribute to healthier cholesterol ratios.
  • • Chromium is a trace mineral which functions to aid the entrance of glucose into cells. Six tablets of HEART SCIENCE provide 300 mcg of Chromium in the form of Chromate® Chromium Polynicotinate and Chromium Picolinate — the most bioactive forms of Chromium. Not many people are familiar with the vital role Copper plays in the body. This trace mineral is found in all tissues of the body, and is particularly concentrated in the heart. Copper is part of several enzymes, and, in this capacity, is necessary for the development and maintenance of the cardiovascular system, including the heart, arteries, and other blood vessels. Because of its role in elastin production, Copper deficiency can severely damage blood vessels and heart tissue. In fact, researchers have found an inverse relationship between Copper status and increased risk for heart damage.10
  • • L-Proline and L-Lysine are two natural amino acids which show exciting promise in helping to prevent fatty deposits in blood vessels. Researchers have recently identified a particle associated with LDL called apoprotein (a) which is believed to be a main culprit in plaque development. 17 Scientific investigation has revealed that the lipoprotein (a) particle has an adhesive quality that makes the lipoprotein fat globule stick inside blood vessels. The sticky fat globules accumulate, leading to fatty deposits in blood vessels and the subsequent clogging of the arteries. L-Proline and L-Lysine tend to form a barrierlike layer around the apoprotein (a) particle, helping to push it away from the blood vessel wall, and impeding deposit.21

    The Regulating Trio

    Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.

  • • Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells.

    Artery Lining Protectors

    Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

    Capillary Strengtheners

    Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

    Heart Smarts

    The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

    Source Naturals HEART SCIENCE™


    The Five Tiered Approach to Heart Health
    Six tablets contain:
    Vitamins and Minerals %USRDA
    Pro-Vit A (Beta Carotene) 45,000 IU 900%
    Vit B1 (Thiamine) 50 mg 3333%
    Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
    Vit B6 (Pyridoxine HCl) 25 mg 1250%
    Coenzyme B6 (Pyridoxal-5-Phosphate)
    25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
    Vit B12 (Cyanocobalamin) 500 mcg 8333%
    Folic Acid 800 mcg 200%
    Vit C (Magnesium Ascorbate) 1500 mg 2500%
    Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
    Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
    Copper (Sebacate) 750 mcg 37.5%
    Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
    Potassium (Citrate) 99 mg *
    Selenium (L-Selenomethionine) 200 mcg *
    Silicon (From 400 mg of Horsetail Extract) 13mg *
    * U.S. RDA not established.
    Other Ingredients and Herbs
    Coenzyme Q10 (Ubiquinone) 60 mg
    L-Carnitine (L-Tartrate) 500 mg
    Hawthorn Berry Extract 400 mg
    Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
    L-Proline 500 mg
    L-Lysine (HCl) 500 mg
    NAG™ (N-Acetyl Glucosamine) 500 mg
    Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
    Taurine (Magnesium Taurinate) 500 mg
    Horsetail Extract (Yielding 31 mg of Silica) 400 mg
    Inositol (Hexanicotinate) 50 mg

    Reference:
    1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
    2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
    3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
    4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
    5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
    6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
    7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
    8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
    9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
    10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
    11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
    12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
    13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
    14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
    15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
    16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
    17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
    18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
    19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
    20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
    21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
    22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
    23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
    24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
    25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
    26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
    27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
    28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
    29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
    30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
    31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
    32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
    33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
    34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
    35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.



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    HEART RESPONSE - Comprehensive Support for a Healthy Heart!
    TopPreviousNext

    Date: June 02, 2005 11:51 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HEART RESPONSE - Comprehensive Support for a Healthy Heart!

    Heart Response 60ct

    Today’s modern lifestyle, filled with stress, pollution, overprocessed and fatty foods, and lack of exercise, places great strains on the cardiovascular system. Source Naturals HEART RESPONSE is a broad-range formula that supports cardiovascular health, especially heart muscle contraction, healthy circulation and the generation of cellular energy.

    HEART RESPONSE features clinical potencies of the renowned heart botanical, hawthorn, and significant amounts of the energy nutrients, coenzyme Q10 and carnitine, along with additional nutrients and herbs. Each daily use supplies 600 mg of hawthorn, the same amount used in recent research.

    Supports Heart Health

    HEART RESPONSE was formulated to include key nutrients and herbs known to support the cardiovascular system.

    Hawthorn: Hawthorn, a rich source of flavonoids and procyanidins, has been used traditionally all over the world as a strengthening circulatory and heart tonic.

    Modern research has documented that hawthorn increases coronary blood flow and strengthens the contraction of heart muscle. Hawthorn is also an antioxidant, which scavenges and neutralizes destructive free radicals. It is only when cholesterol is oxidized that it impacts the integrity of arteries.

    Coenzyme Q10: HEART RESPONSE supplies 60 mg daily of CoQ10, a key enzyme in the Electron Transport Chain, the pathway that generates 90% of the ATP “energy currency” needed by the body. Heart muscle requires huge amounts of energy to perform efficiently—it beats more than 100,000 times each day, pumping more than 1,000 gallons of blood through the body. The heart utilizes ATP as an energy source for muscular contraction. CoQ10 also is a fat-soluble antioxidant.

    L-Carnitine: Carnitine is an amino acid-derived substance that supports heart muscle metabolism. Carnitine is needed to carry long chain fatty acids into the cell mitochondria, where they undergo oxidation to generate energy. The heart utilizes fatty acids as a preferred energy source for its metabolism.

    HEART RESPONSE delivers 300 mg per day of carntine. Taurine and Magnesium: Magnesium and taurine work closely together in the body to help maintain the normal electrical rhythm of the heart. Taurine comprises more than 50% of the free amino acid pool in our hearts, and has many electrophysiological effects on cardiac muscle cells. Alterations in magnesium levels can have profound effects on the heart. Magnesium is involved in autonomic control of the heart through several mechanisms. Bromelain: Bromelain is an enzyme mixture prepared from pineapple stems. Pineapple has been used for its health benefits for more than 500 years.

    Grape Seed Extract: Grape seed is a source of procyanidins. These plant constituents are strong antioxidants that inhibit lipid peroxidation and scavenge free radicals. In vitro studies have demonstrated that procyanidins support the integrity of connective tissue. Garlic: The use of garlic for its health benefits predates written history. Garlic’s volatile oil includes sulfur-containing compounds such as allicin, which are considered to be important biological constituents.

    Selenium: Selenium is an essential trace mineral that is necessary for the activity of the important antioxidant glutathione. Antioxidants are crucial for protecting cholesterol from oxidation, which in turn helps to maintain healthy blood vessels. B-Vitamins: Preventing an undesirable buildup of homocysteine levels may help support the integrity of arteries. Vitamins B-6, B-12 and folic acid are critical to the regulation of homocysteine levels.

    You can count on Source Naturals’ expert formulators to bring you a product based on the most up-to-date nutritional research. HEART RESPONSE combines traditional botanicals and cutting-edge nutrients, scientifically formulated to deal with many aspects of cardiovascular health. It is available in bottles of 30, 60 and 90 tablets.

    References
    Heinicke, R.M. et al. 1972. Effect of bromelain (ananase) … Experientia. 28(7):844-5. Karpati, G. et al. 1975. The syndrome of carnitine deficiency. Neurology. 25:16-24. Schmidt, U. et al. 1994. Efficacy of the Hawthorn (Cratageus) preparation L1 132 … Phytomedicine. 1:17-24. Upton, R. ed. Hawthorn Leaf with Flower – Cratageus spp. Santa Cruz: American Herbal Pharmacopoeia, 1999.



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    Gluco Sciense - Take Control of your Blood Sugar ...
    TopPreviousNext

    Date: June 02, 2005 10:51 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Gluco Sciense - Take Control of your Blood Sugar ...

    Gluco Sciense for Blood sugar

    Sedentary lifestyles, obesity, and sugar-rich diets are prevalent in our society. The result: challenges to your multiple, interdependent body systems involved with blood sugar levels and insulin activity. Now is the time to learn how a healthy diet and lifestyle can help you maintain healthy blood sugar levels. For further support, Source Naturals offers you GLUCO-SCIENCE™, a breakthrough formula. GLUCO-SCIENCE is uniquely effective because it is a Bio-Aligned Formula™. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance. GLUCO-SCIENCE can help bring your body’s systems for carbohydrate metabolism back into alignment.

  • GLUCO-SCIENCE™ Maintains Healthy Blood Sugar Levels When Used as Part of Your Diet

    A Bio-Aligned Formula™

    GLUCO-SCIENCE is a comprehensive herbal-nutrient formula, based on the newest clinical research into key herbs and special ingredients. Source Naturals studied the scientific research, and then designed GLUCO-SCIENCE. This Bio- Aligned Formula provides targeted nutrition to five different body systems involved with healthy blood sugar levels and insulin activity.

    Glucose/Carbohydrate Metabolism

    GLUCO-SCIENCE supports glucose/carbohydrate metabolism with a range of nutrients. B-vitamins are required for glycolysis and the Krebs cycle, the metabolic pathways by which the body converts glucose into cellular energy. Chromium is believed to work closely with insulin to facilitate the uptake of glucose into cells. Manganese is also involved in glucose uptake. The formula also features herbs from several traditions, such as Gymnema sylvestre.

    Insulin/Pancreatic Activity

    Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. Certain nutrients (see chart) support these vital metabolic processes, including mediation of insulin release and activity, and enhancing insulin sensitivity. N-acetyl cysteine protects pancreatic beta cells from oxidative damage in animal studies. In addition, vanadium, zinc, and selenium are notable for their insulin-like actions.

    Heart and Circulatory System

    Vitamin E supports a healthy lipid status, while myricetin has been shown in animal studies to influence triglyceride levels. Gymnema sylvestre and vitamin C are involved with lipid metabolism. Additional heart-healthy ingredients include CoQ10, garlic, fenugreek, and hawthorn.

    Nervous System

    Antioxidants are important for a healthy nervous system. Lipoic acid helps prevent lipid peroxidation, which can impact nerve function. Many B-vitamins are vital to the metabolic processes of the nerves or are present in the phospholipids of cell membranes. Methylcobalamin, an active form of vitamin B-12, supports the central nervous system. Other supportive ingredients are included (see chart).

    Vision

    GLUCO-SCIENCE provides antioxidants, nutrients and herbs with an affinity for eyes and the physiological processes involved in sight. Alpha-lipoic acid, quercetin, and vitamin C support healthy lens function. Bilberry, shown to support microcirculation in animal studies, is widely recognized for supporting vision.

    Lifestyle Tips for Healthy Blood Sugar Levels: A Strategy for WellnessSM

  • • Eat a Glucose-Healthy Diet: Fiber: Soluble fiber helps modulate glucose absorption and lowers plasma cholesterol levels. Adding 50 grams per day to your diet could help lower blood sugar up to 10%. Foods high in soluble fiber include oranges, grapefruits, raisins, zucchini, oatmeal, oat bran, strawberries and apples. Viscous fibers, including guar gum, psyllium, and galactomannan can be helpful— they should be taken with liquid and mixed with carbohydrate foods. Protein: A high-protein, low-carbohydrate diet is associated with healthy blood sugar levels. Fat: Too much fat may increase your risk for heart disease and/or hardening of the arteries, which compromises circulation. Monounsaturated fats such as olive oil, however, are helpful for managing blood sugar. Glycemic Index: Avoid sugar and other foods with a high glycemic index. Different carbohydrates evoke different glycemic responses. Beans, peas, and oats, for example, raise blood glucose levels much less than bread and potatoes. The Glycemic Index, a useful educational tool in choosing foods to help modulate blood glucose levels, is available in the American Journal of Clinical Nutrition [1995;62:871S-93S (88)], or go to the Internet at www.mendosa.com/gilists.htm.
  • • Maintain a Healthy Weight: If you are overweight, lose weight. Although a Body Mass Index (BMI) between 18.5 and 22 is considered “healthy,” problems arise at a BMI of 22, especially for women.
  • • Exercise: Exercise lowers blood sugar and helps reduce risks associated with elevated levels, such as nerve and eye damage. Exercise also improves insulin sensitivity, and supports heart function and circulation. Try to get 20-45 minutes of aerobic exercise at least 3 days per week.
  • • Maintain Healthy Blood Pressure Levels: If your blood pressure is 140 over 90 or higher, you are more likely to experience challenges to healthy blood sugar levels. Eat a “DASH Diet” containing 8-10 servings of fresh fruits and vegetables, 2-3 servings of low-fat dairy products and less than 2,400 mg of sodium per day.
  • • Stop Smoking: Smoking raises glucose levels and aggravates related health problems.
  • • Manage Stress: During stress, the level of many hormones increases and stores of glucose are released into your bloodstream, clogging and weakening vessels and capillaries. You can relax and reverse the hormonal response to stress by practicing deep breathing, meditating or doing yoga, exercising regularly, or talking with friends, family, or a support group.

    Help Maintain Healthy Blood Sugar levels with Gluco-sciense.

    Glucose/Carbohydrate Metabolism American Ginseng, Bitter Melon, Blueberry, Fenugreek, Gymnema sylvestre, Maitake, Myricetin, Pterocarpus marsupium, Chromium, Magnesium, Manganese, Vitamins B-1, B-2, B-5, B-6 & B-12, Biotin, Inositol, Niacinamide Insulin/Pancreatic Activity alpha-Lipoic Acid, Bitter Melon, Gymnema sylvestre, Maitake Fruit Body, Myricetin, N-acetyl-L-Cysteine, Pterocarpus marsupium, Taurine, Chromium, Manganese, Selenium, Vanadium, Zinc Heart and Circulatory System Bilberry, Blueberry, CoQ10, Fenugreek, Garlic, Grape Seed, Gymnema sylvestre, Hawthorn, Myricetin, Taurine, Siberian Ginseng, Magnesium, Selenium, Vitamins B-6, C & E, Folic Acid, Niacinamide Nervous System alpha-Lipoic acid, Glutamine, Magnesium, Taurine, Vitamins B-1 & B-6, Biotin, Choline, Inositol, Methylcobalamin Vision alpha-Lipoic Acid, Bilberry, Quercetin, Taurine, Zinc, Vitamins B-6, C & E



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    Fibro Response - Feel your Vitality ...
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    Date: June 02, 2005 09:56 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Fibro Response - Feel your Vitality ...

    Fibro Response

    Millions of Americans, the majority of them women, are looking for a product to soothe muscles, relieve joints, support energy, and assist the liver’s natural detoxification process. Source Naturals FIBRO-RESPONSE is based on recent research into the physiological mechanisms involved in muscular metabolism. This research has given new hope to millions of people.

    Fibro-Response: A Bio-Aligned Formulation™ FIBRO-RESPONSE is the latest in a series of formulas we refer to as Bio- Aligned Formulations. We evaluate the underlying causes of system imbalances, then design products that support alignment and harmony in your body’s interdependent systems and functions. These formulas provide targeted nutrition to help create Body Systems in Harmony™.

    FIBRO-RESPONSE was designed to help bring harmony to the interdependent systems and functions that influence joint and muscle health. Our muscles need energy and oxygen to prevent them from becoming fatigued. FIBRO-RESPONSE soothes muscles and joints by supporting oxygen supply and energy production, provides powerful antioxidants for healthy joints and connective tissue, assists healthy liver function, and supports the nervous system and circulation. The ingredients were carefully selected to influence a range of body systems. Some were included for their combined effects with other ingredients; some play important roles in more than one body system.

    Muscles and Energy Production: Our muscle cells are powered by adenosine triphosphate (ATP), a compound popularly referred to as “the energy molecule.” ATP supplies energy for all the body’s myriad physiological processes. To provide this chemical energy, the body generates and uses an amazing two to three pounds of ATP every day! ATP production occurs through a series of complex chemical reactions, including the Krebs cycle and the electron transport chain—and these energy production systems in turn require sufficient nutrients. Malic acid, a natural fruit acid that is also produced in our cells, and the essential mineral magnesium, are critical components of the energy production cycle in muscle cells. FIBRO-RESPONSE supplies both in the amounts used in recent scientific research. Additional ingredients that support energy production include coenzyme Q10, a coenzyme in the energy- producing pathways; manganese, which activates many metabolic enzymes; and copper, an important component of energy-producing enzymes. Pantothenic acid, and alpha-lipoic acid help form coenzyme A, a primary starting material for ATP production (pantothenic acid also supports the adrenal glands). Vitamins B-1, B-2, niacin and B-6 are all required for energy production.

    Connective Tissue: Healthy connective tissue is essential for proper muscle function. MSM dietary sulfur supports the integrity of connective tissue and joints. MSM is included in FIBRO-RESPONSE in the amount used in recent joint health studies. Vitamins A and C, zinc, manganese, and copper all have important roles in supporting connective tissue. Liver Support: The liver is the largest and one of the most important body organs. Its vital functions include clearing the blood of toxins, and producing bile, which aids in fat digestion and carries waste products away from the liver. Liver detoxification is essential for muscle and joint comfort. Silymarin from milk thistle seeds is an important contributor to the support of healthy liver function. N-acetyl cysteine serves as a precursor to glutathione, a critical selenium-containing antioxidant produced in the liver, which binds to toxins to help remove them from the body. Alpha-lipoic acid and coenzyme Q10 play important roles in supporting liver health. This is partly because they are components of the body’s energy production process, and the liver demands a great deal of energy. FIBRORESPONSE also contains a classic Chinese herbal combination traditionally used to harmonize liver “chi” or “energy”: bupleurum, ginseng, pinellia, skullcap, ginger, cinnamon, and licorice. Their actions are complemented by the traditional Western herb dandelion.

    Antioxidant Support: Antioxidants protect tissues and joints from highly destructive molecules called free radicals. Alpha-lipoic acid, termed the “ideal antioxidant,” complements the antioxidant activity of beta carotene and coenzyme Q10. Nacetyl cysteine, best known for supporting the liver, is also highly valued as an antoxidant. Zinc, selenium and copper support our natural defenses. Together, they provide a full armory of powerful antioxidants for joints and connective tissue.

    Nervous System Support: Ginkgo biloba is renowned for promoting blood flow to the brain. This is crucial, since brain tissue is very metabolically active, accounting for 2% of our body weight, yet using 15% of our total energy supply. GABA is an inhibitory neurotransmitter that may regulate the nervous system and support clear focus. The herb skullcap, and vitamin B-6, add further support.

    Taking Back Your Life: A Strategy for WellnessSM

    Source Naturals’ expert formulators have created an experiential product that can make a difference in the way you feel. But supplementation is only part of the picture. Healthy lifestyle habits can redefine and empower your own strategy for wellness.

    Rest and Relaxation. Deep, uninterrupted sleep is essential for energy and a healthy nervous system. Sleep 8 to 10 hours nightly and aim to finish meals two hours before retiring.

    Exercise. Even if you feel exhausted and it hurts to move your muscles, you must keep moving. Start easy with nonimpact movement—yoga is an excellent beginning. Do some gentle stretches, followed by 5 to 10 minutes of blood-pumping activity (i.e. biking, stair-stepping, or dancing). Listen to your body: increase activity time only when it feels comfortable. Food and Nutrition. You’ve heard it before but now it’s time to pay attention: eat healthy. Avoid spicy, oily foods and choose light, mild alternatives. Go easy on sugar and incorporate whole grains into your diet. Enjoy steamed vegetables, alternate brown and white rice, and eat less red meat and more fish or soy. Reduce or eliminate milk products. Relax and take time to chew. And drink LOTS of water—it is essential for hydrating the body, flushing out wastes, and absorbing nutrients.

    Breathing. Many people hold their breath unintentionally, often as a result of stress or anxiety. This can become a habit, reducing blood oxygen, interrupting the pumping mechanism of the diaphragm that helps circulation, and causing muscles to become tense. Breathe deeply and feel your lungs expand and fill. Notice how different you feel.

    You have in your hand a powerful, comprehensive formula. Combined with a healthy lifestyle FIBRO-RESPONSE can help you make lasting changes that will empower you throughout life.

    FIBRO-RESPONSE is available in bottles of 45, 90 and 180 tablets.

    References Abraham, G. and J. Flechas. 1992. J. Nutritional Medicine (3): 49-59. American Medical Association, Encyclopedia of Medicine. New York: Random House, 1989. Garfinkel, L. and D. 1985. Magnesium (4): 60-72. Russell, I.J. et al. 1995. J. Rheumatology 22(5): 953-8.

    Targeted Nutrition Muscle Cell Metabolism Malic Acid, Magnesium, CoQ10, Vitamin B-1, (ATP Production) Vitamin B-2, Vitamin B-3, Vitamin B-6, Manganese, Pantothenic Acid, Copper, alpha-Lipoic Acid. Connective Tissue MSM, Vitamin A, Vitamin C, Zinc, Manganese, Copper Liver Silymarin from Milk Thistle, N-Acetyl Cysteine, Ginkgo Biloba, Dandelion Root, Chinese Liver Blend (Bupleurum, Skullcap, Panax Ginseng, Pinellia Root, Ginger, Cinnamon, Licorice Root) Antioxidant Support N-Acetyl Cysteine, alpha-Lipoic Acid, Beta Carotene, CoQ10, Zinc, Selenium, Copper, Nervous System GABA, Skullcap, Ginkgo Biloba, Vitamin B-6.



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    Life Force Multiples -- Source Naturals
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    Date: May 21, 2005 10:24 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Life Force Multiples -- Source Naturals

    Life Force Multiple Vitamin

    Life Force is a Bio-Aligned Formula that goes deep to support your multiple, interdependent body systems. This comprehensive blend of herbs, nutrients and special ingredients addresses seven primary body systems: the brain and nervous system, liver, heart and circulation, immune system, musculoskeletal system, energy and metabolism, and antioxidant defense. While typical multiples supply just enough ingredients to meet minimum requirements, Life Force Multiple contains the Core Four™ - CoQ10, alpha lipoic acid, silymarin and N-acetyl cysteine - plus other critical nutrients not found in common multiples.



  • Life Force Capsules 60caps

  • Life Force Capsules 120 caps

  • Life Force Capsules 180caps

  • Life force Iron Free 60caps

  • Life Force Iron Free 120 caps

  • Life Force Iron Free 180caps



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