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Joint Support Supplement from NOW Foods
Date:
October 26, 2022 12:32 PM
As we age, it's not uncommon for our joints to start feeling a little stiff and sore. This is especially true if we've led an active lifestyle and put a lot of wear and tear on our joints over the years. If you're looking for a way to help support your joints and keep them healthy, you may want to try NOW Foods Joint Support™ formula. How NOW Foods Joint Support Works NOW Foods Joint Support™ is a combination of nutrients and other ingredients that help to support the formation and function of healthy joint tissue.* Joint Support™ provides Vitamin C, Manganese and Copper, which are critical for the production and maintenance of healthy joint structures.* It also has Zinc, B Vitamins and Boswellin®, which can help to support the body's proper response to everyday joint stress.* Glucosamine is included as an essential structural component that is naturally present in bones and joints.* The Ingredients in NOW Foods Joint Support Vitamin C is an antioxidant that helps to protect cells from free radical damage.* Manganese and Copper are co-factors in several important enzymes that are required for the production of collagen.* Zinc is involved in collagen synthesis.* B Vitamins are important for energy metabolism.* Boswellin® is a standardized extract of Boswellia serrata gum resin that has been used traditionally for supporting joint function.* Glucosamine is an amino sugar that occurs naturally in the human body and is a key component of cartilage.* In Summary: If you're interested in trying NOW Foods Joint Support™ formula, you can purchase it online or at many health food stores. Be sure to read the instructions carefully before taking and follow all directions provided. You should always consult with your doctor before taking any new supplements, especially if you have any existing medical conditions or are taking any medications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6529) D-Flame - Herbal Support for a Healthy Response to Stress
Date:
October 07, 2022 10:26 AM
Feeling stressed? You're not alone. In today's fast-paced world, it's more important than ever to find natural ways to support our bodies in responding to stress. Introducing D-Flame, a carefully crafted blend of herbal extracts that may help to support a healthy response to physiological stress. Read on to learn more about the key ingredients in D-Flame and how they work together to keep your body operating at its best. The Science Behind D-Flame D-Flame contains a unique blend of botanical extracts that work together to support the body's natural response to stress. Here's a closer look at some of the key ingredients in D-Flame and how they contribute to its ability to promote a healthy stress response: Holy Basil Extract - Holy basil is an ayurvedic herb that has been used for centuries in India for its many purported health benefits. Among these is the ability to help the body adapt to stress by supporting the activity of key stress mediators. Ursolic Acid - Ursolic acid is a type of triterpenoid compound that is found in a variety of plants. It has been shown to possess anti-inflammatory and antioxidant properties, which may help to protect cells from damage caused by oxidative stress. Turmeric Extract - Turmeric is a well-known spice with powerful antioxidant activity. Its active ingredient, curcumin, has been shown to modulate the activity of enzymes involved in inflammation, helping to keep inflammation levels in check. Ginger Extract - Ginger has long been used as a natural remedy for digestive issues like nausea and indigestion. It also possesses potent anti-inflammatory activity, which may help to reduce pain and swelling associated with occasional overexertion or injury. Green Tea Extract - Green tea is rich in antioxidants and polyphenols, which may help protect cells from damage caused by free radicals. It also contains caffeine, which has been shown to increase alertness and focus while also reducing fatigue. Boswellin® - Boswellin® is an extract of the herb boswellia serrata that has been shown to inhibit the production of pro-inflammatory molecules known as leukotrienes. This action helps to reduce inflammation throughout the body. Bromelain - Bromelain is an enzyme found naturally in pineapple that possesses powerful anti-inflammatory activity. It works by inhibiting the production of pro-inflammatory cytokines, helping to reduce inflammation and pain associated with conditions like joint pain and arthritis. Baikal Skullcap - Baikal skullcap is an herb native to Southeast Asia that has traditionally been used as a remedy for digestive issues and skin ailments. It also possesses potent anti-inflammatory activity, which makes it ideal for alleviating occasional pain and swelling associated with injury or overexertion. Resveratrol - Resveratrol is a type of phytonutrient that is found in grapes, berries, and other plant foods. It has strong antioxidant activity and has also been shown to modulate the activity of genes involved in inflammation, making it an effective tool for reducing chronic inflammation throughout the body.* Berberine - Berberine is a bitter alkaloid compound that is found in a variety of plants including goldenseal, barberry, and Oregon grape root. It has powerful antimicrobial activity against bacteria, viruses, and fungi.* Additionally, berberine has strong anti-inflammatory activity, making it ideal for alleviating occasional pain and swelling associated with injury or overexertion.* In Summary: D-Flame is an all-natural blend of botanical extracts that have been traditionally used for centuries to support the body's response to stress.* These herbs work together synergistically to modulate key enzymes and mediators involved in inflammation.* This action helps reduce chronic inflammation throughout the body.* Additionally, these herbs also help protect cells from damage caused by oxidative stress.* If you're looking for an herbal supplement to help support your body during times of stress, look no further than D-Flame!*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6487) D-Flame - Herbal Support for a Healthy Response to Stress
Date:
October 06, 2022 04:01 PM
Feeling stressed? You're not alone. In today's fast-paced world, it's more important than ever to find natural ways to support our bodies in responding to stress. Introducing D-Flame, a carefully crafted blend of herbal extracts that may help to support a healthy response to physiological stress. Read on to learn more about the key ingredients in D-Flame and how they work together to keep your body operating at its best. The Science Behind D-Flame D-Flame contains a unique blend of botanical extracts that work together to support the body's natural response to stress. Here's a closer look at some of the key ingredients in D-Flame and how they contribute to its ability to promote a healthy stress response: Holy Basil Extract - Holy basil is an ayurvedic herb that has been used for centuries in India for its many purported health benefits. Among these is the ability to help the body adapt to stress by supporting the activity of key stress mediators. Ursolic Acid - Ursolic acid is a type of triterpenoid compound that is found in a variety of plants. It has been shown to possess anti-inflammatory and antioxidant properties, which may help to protect cells from damage caused by oxidative stress. Turmeric Extract - Turmeric is a well-known spice with powerful antioxidant activity. Its active ingredient, curcumin, has been shown to modulate the activity of enzymes involved in inflammation, helping to keep inflammation levels in check. Ginger Extract - Ginger has long been used as a natural remedy for digestive issues like nausea and indigestion. It also possesses potent anti-inflammatory activity, which may help to reduce pain and swelling associated with occasional overexertion or injury. Green Tea Extract - Green tea is rich in antioxidants and polyphenols, which may help protect cells from damage caused by free radicals. It also contains caffeine, which has been shown to increase alertness and focus while also reducing fatigue. Boswellin® - Boswellin® is an extract of the herb boswellia serrata that has been shown to inhibit the production of pro-inflammatory molecules known as leukotrienes. This action helps to reduce inflammation throughout the body. Bromelain - Bromelain is an enzyme found naturally in pineapple that possesses powerful anti-inflammatory activity. It works by inhibiting the production of pro-inflammatory cytokines, helping to reduce inflammation and pain associated with conditions like joint pain and arthritis. Baikal Skullcap - Baikal skullcap is an herb native to Southeast Asia that has traditionally been used as a remedy for digestive issues and skin ailments. It also possesses potent anti-inflammatory activity, which makes it ideal for alleviating occasional pain and swelling associated with injury or overexertion. Resveratrol - Resveratrol is a type of phytonutrient that is found in grapes, berries, and other plant foods. It has strong antioxidant activity and has also been shown to modulate the activity of genes involved in inflammation, making it an effective tool for reducing chronic inflammation throughout the body.* Berberine - Berberine is a bitter alkaloid compound that is found in a variety of plants including goldenseal, barberry, and Oregon grape root. It has powerful antimicrobial activity against bacteria, viruses, and fungi.* Additionally, berberine has strong anti-inflammatory activity, making it ideal for alleviating occasional pain and swelling associated with injury or overexertion.* In Summary: D-Flame is an all-natural blend of botanical extracts that have been traditionally used for centuries to support the body's response to stress.* These herbs work together synergistically to modulate key enzymes and mediators involved in inflammation.* This action helps reduce chronic inflammation throughout the body.* Additionally, these herbs also help protect cells from damage caused by oxidative stress.* If you're looking for an herbal supplement to help support your body during times of stress, look no further than D-Flame!*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6486) Boswellia - The Anti-Inflammatory Herb
Date:
July 23, 2015 03:07 AM
Boswellia is some times referred to as Indian frankincense or boswellin. It comes from a tree known as boswellia serrata that is found to grow in the dry areas of India. Boswellia is said to have 55% of Boswellic acid. For centuries, many Indian healers have always taken the advantage of the anti-inflammation property of this tree. The bark's gummy resin contains anti-inflammation content in higher percentages - its known as salai guggal. In the modern world, preparations are done from a purified extract of the resin and normally packed in cream or pills which are then used mainly to reduce inflammation; rheumatoid or osteoarthritis arthritis. Unlike nonsteroidal anti-inflammatory drugs, like ibuprofen, which is one of the accepted treatments for joint inflammation, - boswellia according to research does not show signs of stomach irritation. It's also sometimes effective when it comes to back pains and other chronic related intestinal disorders. Its health benefits, according to research by scientists, has been outlined that this herb has specific and very active anti-inflammation ingredients. These ingredients are commonly known as boswellic acids. In the field of animal studies, boswellic acids have been proven to reduce inflammation. They improve rapidly the blood flow to the joints. They also do block those chemical reactions that always sets the stage for inflammation that cause chronic intestinal disorders. Boswellia maybe taken internally or even applied topically to the affected joints to help relieve inflammation that is associated with joint disorders. These always increase joint mobility and lessen the morning stiffness. In a study that was conducted involving 175 patients suffering rheumatic disorders such as rheumatoid arthritis, exactly 122 participants were found to experience reduced inflammation and stiffness after using boswellia for two to four weeks. Boswellia's inflammatory component helps reduce stiffness and aching, especially when associated with the low back pains. Though a lot of researches done shows that boswellia is effective when taken orally, creams also appear to be soothing all together. Boswellia also seems to reduce the inflammation related with Crohn's and ulcerative colitis disease, of which both are painful intestinal disorders. It's said to be able to accomplish this without actually the risk of gut irritation which is mainly associated with lots of convectional pain relievers. In the ?year 1997, a study was conducted involving ulcerative colitis victims, 82% those who took this boswellia extract like 3 times in a day, they experienced total and complete remission of this disease.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3180) The working principle of Curamin
Date:
March 22, 2013 11:49 AM
Curamin is a natural pain reliever that functions well. It has four very powerful ingredients with synergistic properties which make it very efficient in pain relieving. These ingredients are: Curcumin longa: a compound that is used to prevent several inflammation pathways in the human body and is a powerful antioxidant. Boswellia serrata: a substance which slows down the performance of inflammatory enzyme. Nattokinase is a type of enzyme which assists the cardiovascular system and also helps other inclusions to go to other regions of the human body. DLPA stops the disintegrating of enkephalins which relieves the body muscles from pain and boost mood.
The above named components works on particular cells which are sending pathways which consist of nerves that relay unwanted signals which are eventually amplified by the interconnected and overlapping pathways. During this process, curamin ingredients come together and blocks the way going to these signaling pathways which in the long run gets rid of the messages being sent. It's very good to put into consideration that it's not the same system used with conventional synthetic medications which include; aspirin, paracetamol, ibuprofen and diclofenac which are used to aim at one particular pathway and leave other subsidiary pathways unchecked. Curamin works in very distinct ways which makes it to be reliable and effective. These ways are:
Curcumin is a system modulator which immunes and safeguard the body from oxidative stress. EuroPharma Curamin is a way in which the body provides temporary relief of pain and eventually improving the natural defense mechanism of the body. Curcumina is a component of Curamin which supports the natural anti-inflammatory response of the body. Enzyme Nattokinase is a significant component of Curamin which aids in circulation of nutrients to get where they are required and helps in getting rid of waste from the body. It also balances fibrinogen levels in the body which is crucial since too much of it leads too pain in the muscles. It is therefore advisable to use curamin since it has no side effects.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2833) How Curamin Combats Inflammation Pain
Date:
December 19, 2012 12:08 PM
Fact: You can manage pain with natural remedies! Study has revealed the sad fact that four out of every five Americans perceive that pain is a natural inevitable part associated with old age. Athletes on the other hand believe that severe pain is essential for physical fitness. Many people again, think that there are certain disorders that ignite pain and you can do less or nothing to relieve the ache. In fact, 28% of America's population believes that there is no solution that can eliminate their personal pain concerns. In the contrary, Curamin by EuroPharma is a highly effective herbal remedy that combines four powerful and clinically proven ingredients, into a single award-winning product that offers an ultimate level of pain relief. Here is a look into how Curamin relieves inflammation pain. #Curamin's Ingredients The secret behind Curamin's power is blending the best of the best. These ingredients are well known for their fast action in relieving pain associated with inflammation especially in the bones and joints. Here are the four main ingredients used in the formulation of this unprecedented pain reliever. *DLPA (DL-phenylalanine) This is a double part amino acid (D phenylalanine & L phenylalanine) that impedes the breakdown of the enkephalin compound, also known as the positive mood enhancer. In addition to that, DLPA converts the L phenylalanine into tyrosine so as to enhance the secretion of two brain chemicals; norepinephrine and dopamine, which ease pain and dissolve inflammation. *Boswellia Boswellia serrata, also known as Indian frankincense is an anti-inflammatory herb used in the Curamin formula. The boswellic acids prevent the hyperactivity of an enzyme called lipoxygenase, which is often associated with inflammation. This way, it effectively combats inflammation pain. *Nattokinase This natural ingredient is extracted for a Japanese fermented cheese known as natto, hence its name. The production of this beneficial enzyme can be attributed to a certain bacterium called Bacillus natto. Its benefits in relieving pain come through its action of breaking down clots, promoting the circulation of blood. Thickened blood can intensify pain, and by promoting blood circulation, all other Curamin ingredients are well distributed to every single part of the body. *Curcumin This powerful, natural compound derived from turmeric requires no detailed introduction. It promotes the body's natural ability to combat inflammation and also contains anti-oxidant properties that are very useful in preventing tissue damage. Its functionality in pain relieving is behind its effectiveness in cutting off pathways that lead to inflammation. Numerous studies have also depicted its ability to promote cognitive-enhancing as well as anti-depressant benefits by igniting neuro-protective brain functions and moderating pain neuro-transmitters. #How Curamin Relieves Pain This proprietary formula combats inflammation pain by promoting the body's defense mechanism. In addition to that, it features curcumin BCM-95 which has an enhanced oral bioavailability and is highly soluble, thus availing a full spectrum or curcuminoids that fight pain in a flash. Additionally, the amino acids and Boswellia used in the formulation of Curamin helps the body to absorb the pain alienating ingredients quickly, which earns Curamin its well deserved fast-acting characteristic. Curcumin BCM-95 has extended blood retention; one among the many attributes that makes Curamin stronger than other plain curcumin products. We cannot forget to mention the fact that Curamin is associated to no known side effects. It combats all types of pain ranging from occasional back pain to chronic pain caused by arthritis. So, next time pain becomes a problem, grab a bottle of Curamin and make your life a whole lot easier.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2752) How Does Boswellia Fight Inflammation?
Date:
April 13, 2011 03:57 PM
Boswellia refers to the species of trees where the aromatic gum resin frankincense is obtained from. In herbal medicine, the term Boswellia often means Indian frankincense, which is noted for its potent anti-inflammatory properties. It has a centuries-old association with Ayurvedic medicine, and herbal preparations containing its extracts are formulated for arthritis. It now comes in supplements marketed as a viable treatment for inflammation-induced illnesses, such as arthritis, colitis, and asthma. Asthma Indian frankincense, also known as dhoop in India, is entirely derived from Boswellia serrata, and the common frankincense from a completely different species. The earliest known study looking into its purported benefit as an anti-inflammatory medication was in 1998, and it investigated its effects on asthma. In a span of 6 weeks, the boswellia group took 300 mg of the preparation three times a day and 70 percent experienced a significant improvement in symptoms and a noticeable decrease in incidence of asthma attacks in comparison with the control group. Arthritis In Ayurvedic medicine, boswellia has been utilized for hundreds of years with an emphasis on its use in the amelioration of joint pains. It is generally considered safe, explaining its prevalence in the treatment of arthritis and related disorders. Boswellia was the subject of several studies devoted to better management of osteoarthritis, and these studies published results that attracted more research. Today it is also touted to be useful for rheumatoid arthritis, which is inflammatory in nature. Colitis Recent studies yielded outcomes in favor of its anti-inflammatory claims. In 2007 one study pointed to its medicinal potential in the treatment of colitis, concluding that patients with chronic inflammation of the colon went into remission after regular intake of boswellia. In a similar study, individuals diagnosed with inflammatory bowel disease reported to have benefited from 6 weeks of supplementation while those who sought conventional treatments responded to their medications in a much longer time. 5-lipoxygenase Boswellia remains under scrutiny. Anecdotal evidence has been very positive largely owing to the fact that it hasn’t been linked to any adverse effect at all. But how does it work? There are many chemical reactions which boswellia may be directly involved in. It has been observed that it reduces the synthesis of pro-inflammatory leukotrienes. These mediators of inflammation are produced in the presence of an enzyme called 5-lipoxygenase, which is thought to be counteracted by the high terpene content of boswellia. Leukocytes Triterpenes in boswellic acid, the active ingredient unique to boswellia, are also believed to interfere with the adhesive interactions between leukocytes and endothelial cells present in the gastrointestinal tract. Leukocyte elastase is a serine protease, a special kind of enzyme, released by leukocytes or neutrophils during inflammation. It is postulated that boswellia down-regulates leukocytes and leukocyte elastase in addition to inhibiting the expression of endothelial cells adhesion molecules. Down-regulation of leukocytes will help reduce inflammation and improve health. If you are fighting systemic or joint inflammation, give boswellia a try and feel the difference!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2272) Improve Your Memory Naturall, How Does Huperzine A Help Improve Memory?
Date:
March 26, 2011 10:47 AM
Huperzine A and The BrainHuperzine A is an organic compound naturally occurring in a plant species believed to be one of the oldest vascular plants still in existence. It is derived entirely from the firmoss Huperzia serrata, which is reputed for its memory-enhancing effects in China for the most part of its history. It has gained the attention of researchers and health professionals in the West owing to its purported role as a cholinesterase inhibitor, which delays cognitive decline and brain shrinkage tied to Alzheimer’s disease. It has become popular to people seeking other forms of cholinesterase inhibitors apart from those commonly available in the market, and anecdotal evidence points to its noticeable effects on symptoms of Alzheimer’s disease. Increases Quantities of Neurotransmitters Cholinergic neurotransmission makes use of a system of nerve cells that participate in anti-excitatory activities in the central nervous system. These neurons rely on an endogenous compound called acetylcholine, which acts as the primary neurotransmitter in the brain, the brain stem, and the spinal cord. Acetylcholine as a neurotransmitter is synthesized from esterified acetic acid and choline, but its lifespan is cut short by the enzyme cholinesterase. This enzyme induces the hydrolysis of this neurotransmitter back into choline and acetic acid. Huperzine A works on the principle of inhibiting the enzyme cholinesterase, resulting in a longer acetylcholine lifespan especially those in the brain. By doing so, it also raises the levels of other neurotransmitters that are in the employ of nerve cells. Affects Chemical Compounds in the Brain Nerve cells constantly respond to many chemical brains that may induce more neuronal activities that affect cognitive function. The busier nerve cells become, the sooner the brain is able to sustain concentration. An increase in neurotransmitters has been tied to greater neuronal activities. Also, there are exogenous chemical compounds that when ingested pass the blood-brain barrier and act as stimulants to nerve cells, such as caffeine. It has been postulated that Huperzine A provides a nootropic effects by influencing endogenous brain chemicals and consequently stimulating neuronal activities in a similar way caffeine does. However, unlike caffeine, it is not considered a psychoactive drug. More importantly, a more recent study points to its effects on nerve growth factor, or NGF, a protein responsible for the growth and upkeep of nerve cells. This means Huperzine A not only influences brain chemicals, but also makes sure that nerve cells survive. Creates Positive Effects on Neuroplasticity In contrary to former claims that the brain does not change after early developments during infancy, recent studies point to changes in both chemical makeup and cellular structure as we age. These changes are a response to both physiological stimulus and learning experience. New nerve cells are created as we spend more time sharpening our mental skills, much like how the muscles respond to continuous exercise and body toning. This process of change in the brain is called neuroplasticity, which Huperzine A supports by acting as a vitamin-like nutrient to nerve cells and neurotransmitters. If you want to improve brain function and memory, give Huperzine A a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2259) Use Curamin For Painful inflammation and see how your life can change!
Date:
June 15, 2010 05:10 PM
Everyone experiences occasional pain at some time in their lives. We use the word pain in our jargon to describe something unpleasant and to indicate the necessity of toughening up such as “no pain no gain”. As common as the word pain may be, there are many misconceptions about pain. Four out of five Americans believe that occasional pain is just natural and unavoidable due largely to getting older. More than one quarter of Americans believe there is absolutely nothing they can do to relieve their personal pain. Pain is a warning signal that something has gone wrong in the body or that something is damaged. Pain is so unpleasant that it motivates you to remove yourself from the cause of this damage as quickly and completely as possible. There are four ways to relieve occasional pain: 1. You can leave the pain alone, but flood the body with feel-good substances that push the pain signals out from your consciousness (drugs). 2. you can put the person asleep and do surgical procedures to cut nerves and stop the pain. 3. You can impact the nervous system the internal wiring that carry the pain signals to dull them so that the signal becomes less distinct and weaker. 4. You can target what is causing the pain in the first place (most recommended). Occasional pain can be perfectly normal for instance, starting a new exercise routine when you are a bit out of shape. When dealing with type of pain, helping the body to balance its inflammation response can have tremendous impact. This is where curamin is the answer to pain problems. Curamin contains four high potency ingredients that make it work so well. The first ingredient is curcumin from Turmeric. Curcumin is a super antioxidant with a ORAC value of 1592.27 each gram. That’s 24 times stronger than blueberries. Curamin also contains Boswellia, DLPA (DL-phenylalanine) which help fight inflammation and maximize the endorphins and enkiphalins in our own body. It finally contains nattokinase which is a systemic enzyme known to help improve circulation. They all break down as follows: DLPA: DL-phenylalanine is an amino acid consisting of equal parts D-phenylalanine and L-Phenylalanine. D- inhibits the breakdown or compounds called enkephalins. Enkephalins are associated with positive mood and have been shown to relieve occasional muscle pain due to exercise or overuse. L- is converted into tyrosine, which in turn is used to produce brain chemicals norepinephrine and dopamine. Boswellia: Clinically tested boswellia helps reduce the activity of the inflammatory enzyme, 5-LOX (lipoxygenase). A compound (beta boswellic acid) found in boswellia which interferes with its benefitical activity has been removed, greatly increasing the effectiveness of this extract. Curcumin: Curcumin, a compound found in the spice of turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. Some of the benefits associated with curcumin include immune system modulation, protection from oxidative stress, and support the body’s natural anti-inflammatory response. The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefit. (Found in Curamin) Nattokinase: the enzyme nattokinase helps promote blood flow, aiding the other ingredients in the formula to reach all areas of the body. So if you are suffering from chronic pain, give curamin a try and see how well you can feel. If you are concerned about its effectiveness, have no fear, VitaNet ®, LLC offers a 100% Money back guarantee if the product does not work for you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2167) Fight Inflammation With Inflama-Care - Anti-inflammatory herbal combination
Date:
March 22, 2010 09:07 PM
Turmeric / Boswellia Complex Our modern lives have untold benefits, as well as great challenges. Our dependence on man-made toxic chemicals, junk food, nutrient-imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health. These unhealthy lifestyles and environmental changes have set our immune system on overdrive, a state call metabolic inflammation. Planetary Herbals Inflama-Care is a potent, herbal response to these modern challenges. The Inflammation Cycle As toxins and stress begin to alter our body chemistry and change the function of vital tissues, our body reacts with metabolic inflammation just as if it were being attacked. This reaction may result in a perpetual cycle of chemical imbalances and suboptimal health. Yet metabolic inflammation is often below the threshold of perception, not noticed or felt for years after its starts. It is only much later that the altered biochemistry and the system imbalances that it generates are noticed. A Powerful Herbal Blend Inflama-Care helps support the body’s natural response to metabolic inflammation. The main component of the formula is the rhizome of the curcuma species, long used as a spice in India. Known worldwide as turmeric (Curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines—inflammation messengers. This world-renowned spice is supported by boswellia, which inhibits proinflammatory enzymes, and ginger, an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skull cap, corydalis, holy basil, and hops. The PhytoDynamic Difference
Planetary Herbals presents inflama-Care to help maintain the body’s biochemical balance and integrity. Inflama-care was formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. Thie result: herbal products unsurpassed for quality and consumer satisfaction.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2132) Huperzine And Memory
Date:
December 04, 2008 01:20 PM
Chinese club moss goes by the name Huperzia serrata, and gives its name to the sesquiterpene alkaloid it contains: huperzine A. This alkaloid has been found to be a superstar in the arena of brain-saving treatments for conditions such as Alzheimer's and age-related senility. Studies in China have found up to 60% improvements in the cognitive functions of such patients, and its potential has been recorded in the Journal of the American Medical Association. This is no mere folk remedy, and is the subject of serious study. Known as Qian Ceng Ta, Chinese club moss has been a part of traditional Chinese medicine for centuries for the treatment of fever and inflammation, which is not surprising considering that most plants contain antioxidants and anti-inflammatories. However, what is unusual is the fact that it has also been found effective in treating some forms of dementia and depression, and also helps to reduce the incidence of panic attacks in those susceptible to them. Not only that, but the plant has been found to possess diuretic properties, and a reduction in the swelling associated with water retention could also help to reduce the pain and other effects of swelling and inflammation. However, for now it is its effect on the brain that we are concerned, and research has indicated the likely mechanism by which huperzine A works. Huperzine is an enzyme inhibitor - specifically inhibiting the enzyme acetylcholinesterase that breaks down acetylcholine, a neurotransmitter involved in the processes of memory, learning and mood. Outside the brain, it is involved in the movement of skeletal muscle tissue as well as in the regulation of cardiac and other smooth muscles such as those of the blood vessels. When acetylcholinesterase (AChE) attacks acetylcholine (ACh), the latter attaches to a chemical site on the enzyme where it is then destroyed. It is a deliberate function of the body, designed to terminate a synaptic transmission. The purpose of a neurotransmitter is to allow the transmission of an electrical impulse form one nerve cell to another over a gap between them known as a synapse. Once the transmission has been completed, the enzyme can destroy the neurotransmitter, and then another takes its place. In fact one molecule of AChE can destroy around 5,000 molecules of ACh. However, with age and for other reasons, these neurotransmitters can become depleted so that it becomes increasingly more difficult for brain cells to communicate with each other, and their destruction becomes undesirable. There are drugs available to help prevent this happening (e.g. donepezil, galantamine and tacrine), and so help to improve the memory and mental function of people as they grow older or contract conditions such as Alzheimer's disease. Huperzine A has been found to take up the site in the acetylcholinesterase molecule that would normally have been used by the acetylcholine, and so save it from destruction. The more Huperzine A molecules present, the more acetylcholine available to pass messages between brain cells, and the stronger the cognitive function of the subject or patient. The pharmaceutical drugs mentioned in the previous paragraph work in exactly the same way. This is a very specific reaction, one molecule adopting exactly the same space as the other, and has been proved scientifically by comparing the physical shapes of the two molecules. It's just like a jigsaw puzzle, where only one piece can fit into each position. Except here there are two: Huperzine A and acetylcholine both fit into the exact same place in the chemical structure of the acetylcholinesterase molecule. The biochemistry of the reactions involved is very complex, and shall not be discussed here, but the upshot is that Huperzine A can do exactly the same job as modern drugs to avoid this hydroxylation of the ACh needed for the proper functioning of your brain. In fact, clinical trials have indicated Huperzine A not only to be comparable in effect to the drugs current used, but also likely safer with respect to the possible side effects. This has still to be confirmed, but the National Institute on Aging is currently carrying out a trial to evaluate this claim in tandem with its effect on Alzheimer's disease. It has also been examined at Harvard University for its effect on epilepsy on patients with whom alternative pharmaceutical treatments have been unsuccessful. Another suggested benefit of Huperzine A is that it is an NMDA (N-methyl D-aspartate) receptor antagonist that provides protection against damage to the brain by an excess of glutamates, and that it can also help to protect nerve cells from damage. Since NDMA is responsible for the transmission of some types of pain, the antagonist can also act as an analgesic. There are other benefits that Chinese club moss can provide, and myasthenia gravis is one of them. Although relatively rare, this is a serious condition in which acetylcholine receptors are deactivated on muscle cells. This is achieved through the autoimmune system malfunctioning and creating antibodies against the receptors, and the end result is paralysis and respiratory failure. Huperzine A reduces the AChE available and so might possibly enable the acetylcholine to work more effectively and delay or even stop the deterioration of muscle function. When people hear of muscle paralysis they frequently forget that breathing requires muscle function, as indeed does your heartbeat. This is currently surmise, and studies are being carried out to determine whether or not this usage of Huperzine A is viable. Another promising application of Chinese club moss extract is in preventing organophosphate poisoning. These pesticides permanently suppress acetylcholine. This results in seizures due to a lack of interruption of the signals from nerves to muscles. The seizures can result in rapid death from uncontrollable seizures, or from permanent contraction of the diaphragm muscle that allows breathing. Although no human studies have yet been carried out, animals given Huperzine A prior to organophosphate exposure have survived without seizures. There are no doubts that Chinese club moss and the Huperzine A extracted from it are effective in preventing the suppression of acetylcholine, and in permitting the proper activity of this important neurotransmitter. It is finding an increasing number of potential uses beneficial to the human body, not the least of which would be a partial remedy for some of the effects of dementia and Alzheimer's disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1944) Secondly, the Herb Boswellia
Date:
April 03, 2008 12:43 PM
Boswellia is a tree that has a number of different species that have been used in Ayurvedic medicine. This is a form of Indian medicine that is used today by millions in India, and also in the neighboring Nepal and Sri Lanka. Its approximate translation is ‘Meaning of Life’, or could even be subtended to ‘Science of Life’, and is more a system of health care than the treatment of specific conditions. There are four species of Boswellia: Boswellia carteri, Boswellia frereana, Boswellia sacra and Boswellia serrata, and it is B.serrata that is predominantly used in Ayurvedic medicine to treat a number of conditions, including ulcers, rheumatoid arthritis, dysentery and asthma. It is not coincidence that most of these are inflammatory conditions, and even dysentery is a form of inflammatory colitis. You might be more familiar with Boswellia by the fragrant resin that it produces: Frankincense. There are different grades of Frankincense according to the species and grade of Boswellia, and if you are using the resin for its aroma then that could be an important consideration. However, the active ingredient of Boswellia are the so called boswellic acids that are contained within the resin. It has been used in the treatment of a number of inflammatory conditions including asthma. Many do not realize that asthma is an inflammatory response of the immune system to particulate irritants in the airway such as cigarette smoke and other small particles. In this case the inflammation is caused by the histamine that is released by mast cells sent to the area of irritation by the immune system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1740) Are Inflammation, Immunity, And Allergic Reactions A Role For Supplements?
Date:
November 10, 2007 11:29 AM
Inflammation, immunity diseases and allergic reactions are all connected with your immune system, and the way the body reacts to what it considers to be foreign invaders that are a risk to your health. Although you may not understand that all three have the basic underlying cause, in fact they do, and here is why. Inflammation manifests as pain and swelling in the inflamed area, and not only can the area also get hot, but it can also raise your temperature in general, commonly called a fever. Fever is the body’s way of raising temperature above that at which foreign organisms such as bacteria and viruses can live, so any inflammatory condition that results in fever by definition must be an immune response through the body trying to eliminate foreign invaders. If your body gets injured in any way, your immune system responds, and usually calms down again if decides that the injury is not serious. Your immune system is actually initiated by what are known as pro-inflammatory hormones, such as prostaglandins that stimulate the nerves to signal pain and swell the blood vessels close to the injury to make room for the large white blood cells when they arrive. That also allows blood and plasma to rush out and cause swelling at the site of the injury. Other prostaglandins act to quell the immune response, and get your body back to normal. Another such hormone is a cytokine, which informs the brain of the intrusion. Some cytokines called leukocytes stop the immune system when necessary to prevent the destruction of healthy tissue, and also halt the inflammatory response. If the leukocytes are not working properly, the body can be severely damaged as the immune system becomes uncontrolled and starts to attack healthy tissue. Then there are the histamines that allow you to expel the agents causing the problem by sneezing, watery eyes, runny noses and scratching. They lead lymphatic fluid and blood to the site of the problem in order that the invasion can be attacked and destroyed. It is the histamines that provide what is commonly referred to as an allergic reaction, which is really the immune system coming into action to remove invaders such as pollen, dust mites and any other agent that can cause an allergy. Immunity is caused by introducing small amounts of the agent into the blood, so that the immune system can develop a memory of them. Then, when the same invader returns at a later date, the system can immediately attack them with the antibodies that have been produced. All of these: inflammation, immunity and allergies, are caused by the reaction of the immune system to what it perceives as an invader. Normally these are bacteria and viruses, but sometimes they react to other foreign bodies such as pollen. In some people this provokes no response at all, while in others it provokes the immune system to create antibodies against the pollen, and emit histamine to expel it. Substances that cause allergies are referred to as allergens. Many allergens are environmental, such as dust, pollen and peanuts. Some people are allergic to certain animals, such as cats or dogs, and others to chemicals in the air such as hydrocarbon emissions, particularly when in particulate form. The symptoms can be simple, such as a runny nose, a cough and hay fever or more complex such as hives, eczema and asthma. All of these are caused by the immune system reacting to an invader. There are also foods that cause internal inflammation, such as shellfish and whitefish, eggs and tomatoes. Many of these can be extreme, leading to serious illness and can even be fatal. So what can be done to treat people who are particularly prone to inflammation and allergic reactions? Omega-3 fatty acids have been found to reduce inflammation, unlike their Omega-6 cousins that appear to increase it. Omega-3 oils contain chemicals known as eicosanoids, of which the prostaglandins are an example. While this might seem paradoxical, since prostaglandins are what set off the whole process, there are many types of these. Prostaglandin E2 is the type that leads to allergic immune reactions, and omega-3 fatty acids reduce the concentration of these in the blood. Those who eat little fish tend to suffer more from inflammatory conditions such as arthritis and other conditions indicating a lack of control of the immune system. On the other hand, processed foods contain more omega-6 fatty acids that can promote these conditions. The major components of omega-3 oils are alpha-linolenic acid (ALA) and eicosapentaenoic acid (EPA) and also DHA, docosahexaenoic acid. These are all anti-inflammatories and have been shown to have very positive effects on inflammatory conditions such as rheumatoid arthritis, Crohn’s disease and eczema. Each of these is a different type of inflammatory condition caused by inappropriate immune response. However, it not just fish oils that can help resolve problems with our immune system. Quercetin is what is known as a flavonoid. It is a strong anti-oxidant and natural anti-histamine that combats histamine release and the swelling associated with the immune response to allergens. It also counters the inflammatory agents of arthritis and so helps to reduce the pain associated with many of these conditions. It appears to work better in conjunction with bromelain, a very powerful anti-inflammatory that also possesses anti-allergen response properties. Bromelain is extracted from pineapple stems. Another natural product is a resin extract that is obtained from the Boswellia serrata tree. It has powerful anti-inflammatory properties, and has been recommended for the treatment of arthritis (rheumatoid and osteo), Crohn’s disease and has been suggested as a treatment for asthma, though studies are still under way. However, world wide experience is that Boswellia is effective against gout, psoriasis and ulcerative colitis, to name another three totally different inflammatory conditions. What all of this indicates are two things. First that inflammation, immunity and allergic reactions are connected conditions, and due to either poor control over or an over stimulated immune response to what the body perceives as being abnormal, in the way that hormones and other chemicals that are used to control our immunity detect it to be. Secondly, there are many natural products that can be used as supplements to treat these effects caused by the immune system, and that their effectiveness has been proven, if not by scientific study, then by generations of traditional application as treatments of the symptoms of the conditions concerned.
However, although many have been proved by scientific study, others have not, and you should always refer to your physician before undergoing any treatment other than that prescribed. Also, there is incontrovertible evidence that the role for supplements in the treatment of inflammation, immunity and allergic reactions are beneficial. Many use nothing else.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1625) Do you experience muscle pain and inflammation?
Date:
April 25, 2007 03:30 PM
FlexAgility MAX Everyone experiences muscle pain and inflammation due to overuse and exertion. We’ve all had those softball games, weekend camping trips or chore-intensive days when our body lets us know we’ve overdone it. So, what can you do about it? Well, fortunately, there is a proprietary formula with clinically studied ingredients that provides a natural solution: FlexAgility MAX. FlexAgility MAX is designed to reduce pain and inflammation due to overuse. Its clinically studied ingredients have been shown to help balance the body’s own inflammatory response. Let’s take a look at FlexAgility MAX and answer a few questions you may have about it. Q. What is inflammation? Why does it happen? A. Inflammation is actually an essential part of your body’s natural healing process. When some form of physical stress affects the body, the immune system responds by supplying defensive compounds to the stressed site. This is what causes the fluid build-up, pain and redness we typically associate with inflammation. And until the situation is resolved those symptoms will stick around. So, why is that good? Because without these signals – pain and inflammation – we’d probably do even more damage. In a sense, pain and inflammation are very effective stop signs. The problem is, if our bodies are continuously bombarded by factors that trigger inflammation, these defenders (and their symptoms) are always around. This can mean unnecessary pain and inflammation following overuse and exertion. Q. What does FlexAgility MAX have to do with inflammation? A. FlexAgility MAX provides triple-action activity against occasional pain and inflammation, with powerful antioxidant free-radical scavengers, the enzyme bromelain, and a natural COX-2 inhibitor. Q. So what is COX-2 and why should I inhibit it? A. We’ve all been hearing a lot in the news about COX-2 inhibition and may have wondered about its connection to pain and inflammation. Let’s take a look: Cyclooxygenase is an enzyme that comes in two main types, abbreviated for convenience: COX-1 and COX-2. The COX enzymes regulate compounds involved with inflammation, including prostaglandins. COX-1 is found throughout the body, and maintains the integrity of the stomach lining, circulation and kidneys. COX-2 on the other hand, cruises along the central nervous system – it’s much more attuned to our brain’s sense of “what hurts.” Primarily activated by inflammatory stress, COX-2 generates prostaglandins – the hormone-like defensive compounds that cause the responses we associate with pain and inflammation due to overuse. You can understand why so much research has focused on COX-2 inhibition. Decreasing its activity means short-circuiting the “inflammation cascade” that follows occasional overuse. Because COX-1 is associated with a healthy stomach lining, it is not an enzyme you want to inhibit. Unfortunately, many products don’t know the difference between COX-1 and COX-2 – filing both with one blast. Fortunately, there are ingredients in FlexAgility MAX that can tell them apart. One of them is IsoOxygene. IsoOxygene is a patented hops extract shown in scientific studies to significantly inhibit COX-2, while leaving COX-1 alone. And, it is a 20 times more potent COX-2 inhibitor than other tested popular botanic products, including curcumin and grape seed. Q. How do antioxidants support the body during times of inflammation due to overuse? A. Overall, the body ahs a pretty darn good repair system. However, oxidative stress due to free radical damage can take its toll, especially during times of occasional physical stress. Free radicals and reactive oxygen species can damage cells, because they are hungry, unstable molecules in search of electrons. To find them, they attack other cells. These pillaged cells then become free radicals themselves, setting off a chain reaction of oxidative stress. Free radicals are formed during the body’s normal functions, and can have benefits, such as neutralizing viruses and bacteria. However, in doing do, they erode the body’s own antioxidant defenses, too. And, free radicals typically become very active during times of inflammation due to overuse or other stressors. The good news is that the herbal and antioxidant elements in FlexAgility MAX help support the body’s own natural anti-inflammatory defenses. Take vitamin C, for instance. This extremely well-known antioxidant has been scientifically studied for its beneficial effects on muscle, collagen and connective tissue health. Collagen and connective tissue is what helps hold us together – literally. And famous antioxidant, green tea, has been well-studied for the benefits of a polyphenol called epigallocatechin-3-gallate, or simply EGCG. In scientific and clinical studies, EGCG from green tea works as an overall antioxidant, scavenging free radicals, and supporting healthy collagen. In fact, one study showed that green tea polyphenols supported collagen health by 50% versus only 16% in controls. The green tea extract in FlexAgility MAX is especially focused on these beneficial polyphenols. It’s standardized to contain 70% polyphenols – half from EGCG. The green tea acts in concert with elderberry and ginger in the formula to help prevent oxidative stress to the body due to occasional overuse. Anthocyanins are natural antioxidants found in berries and vegetables. Black elderberry extract, one of the herbal ingredients in FlexAgility MAX, was shown in scientific studies to be more bioavailable – that is, more readily used by the body – than the natural bioflavonoids of other plants. Again, antioxidants help keep the body in optimum health- especially during times of physical stress. Ginger, used for centuries in Ayurvedic medicine, provides strong, natural antioxidant activity. In fact, a recent scientific study found more than 50 separate antioxidants in ginger root. Of course, there are many components of plants that show strong antioxidant properties. A scientific study comparing flavonoid antioxidant activity and inflammation have shown that rutin was the most effective in reducing the inflammation cascade. Boswellia serrata is a tree found growing in the dry, hilly regions of Another antioxidant ingredient in FlexAgility MAX, N-acetylcysteine (NAC), even helps the body produce more of its own antioxidants, cysteine and glutathione. In a double-blind, placebo-controlled clinical study, N-acetylcysteine inhibited occasional pain and inflammation due to overuse and attenuated fatigue by 26% compared to controls! N-acetylcysteine has also been shown in scientific tests to act as an antioxidant, supporting healthy collagen and synovial fluid. The last ingredient, bromelain, provides the enzymatic pathway used by FlexAgility MAX. Bromelain is a proteolytic enzyme derived from pineapple. Clinical and scientific studies showed benefits from bromelain in reducing pain and inflammation from occasional overuse. So, there you have it- the triple action of FlexAgility MAX: COX-2 inhibition (and COX-1 sparing), antioxidant benefits, and enzyme support. Q. Is there another product you’d recommend that I use with FlexAgility MAX? A. One other product I recommend without hesitation is GS-500, a glucosamine sulfate supplement that has been shown to help build and support cartilage. The body’s connective tissue and cartilage include a natural compound called glucosamine. Supplemental glucosamine sulfate is up to 98% absorbable, so more glucosamine reaches the target structures. It has been clinically studied on its effect in building cartilage. About Enzymatic Therapy: Like Chris, Enzymatic Therapy is a trailblazer. Since our founding in 1981, we’ve been leading the industry with innovative natural products. After all, in 1993, Enzymatic Therapy introduced glucosamine sulfate, shown to help build and support cartilage, to the In the intervening years, Enzymatic Therapy has been at the frontline of innovation and invention. Many revolutionary precuts, including Saventaro, Cell Forte, Heartburn Free, Petadolex Patented Brain Support, Whole Body Cleanse, Earth’s Promise, Hot Plants for Him and Hot Plants for Her have been introduced by Enzymatic Therapy. One of the newest products, (and the reason you’re reading this) is FlexAgility MAX. FlexAgility MAX works with the body’s own natural anti-inflammatory pathways to relieve pain and reduce inflammation due to occasional overuse. Our proprietary FlexBend of ingredients, combined with antioxidants and the proteolytic enzyme, bromelain, is unique among natural products.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1529) Safe Solutions for Chronic Pain
Date:
March 30, 2007 12:09 PM
Safe Solutions for Chronic Pain One of the biggest challenged in healthcare today is the problem of pain. There are simply too many people living each and every day with ongoing, unremitting chronic pain. And there are far too many healthcare providers who – for a variety of reasons – are failing to adequately address this serious problem. Recently, 368 doctors who routinely care for patients with chronic pain agreed to take part in a unique study. The doctors were surveyed about the pain medicines hey prescribe, what kind of treatment goals they hope to achieve, and how they felt about their ability to help their patients. They were also presented with four chronic pain vignettes or mock case studies and asked to select the best treatment for each scenario from multiple choice answers. Sadly, many doctors chose the worst treatment options in the case studies. The medications they reported using in their practices did not reflect current pain treatment standards. They tended to set low treatment goals 0 instead of aiming for a least a 75% reduction of pain for their patients, they settled for 10% to 20% reductions. And many of the doctors admitted they lacked confidence in their ability to relieve their patients’ pain and suffering. Adding to the challenge are the almost daily news announcements about dangerous side effects in certain pain medications. Synthetic prescription COX-2 inhibitors, once hailed as the safest of drugs, have been linked to heart attacks, strokes, blood clots, and intestinal bleeding. The over-the counter (OTC) drugs aspirin and ibuprofen kill over 16,000 people each year. And acetaminophen, the most widely used pain reducer in the As a doctor specializing in chronic pain disorders, I know that optimal pain management can be a real challenge. However, I also know: -You do not have to live in chronic pain. -Your chronic pain, no matter what the cause, can be reduced, and usually eliminated. -Chronic pain can be relived both effectively and safely with powerful all-natural compounds. Q. What is chronic pain? A. Sudden, or acute, pain occurs when pain signals immediately fire in your nervous system alerting you to an injury, like a broken ankle, or an illness, such as appendicitis. Once the injury heals or the illness is cured, the transmission of pain signals stop. Ongoing – or chronic pain – is much different. Chronic pain persists. Pain signals keep firing in the nervous system for weeks, months, even years. There may have been an initial injury, such as sprained back muscles, or an initial illness, such as a serious infection. There might be an ongoing cause of pain, such as arthritis, cancer, or fibromyalgia. Chronic pain also occurs without any past injury or evidence of body damage. The most common kinds of chronic pain are headache, low back pain, cancer pain, arthritis pain, and neurogenic pain (pain resulting from damage to nerves or to the nervous system itself). While chronic pain differs in its origin and where it occurs, it is generally your body’s way of saying that something urgently needs attention, and will not o away unless its underlying causes are addressed. These causes can usually be determined if you remember the acronym “SHIN”. This stands for Sleep, Hormonal deficiencies, Infections/Inflammation/Impingement, and Nutritional deficiencies. When these are treated, pain often resolves. Q. Why is it so hard to effectively reduce chronic pain? A. Unfortunately, many physicians’ entire education in pain management consists of “giving nonsteroidal anti-inflammatory drugs or NSAIDs (pronounced en-sayds), COX-2 inhibitors, or acetaminophen and considering narcotics if the patient has cancer. Some NSAIDs, like aspirin and ibuprofen, are available over-the-counter, while others, like the synthetic COX-2 inhibitors are only available with a doctor’s prescription. These mediations are usually inadequate and often toxic when used for chronic pain. And they do not address the problem(s) that the pain is trying to alert you to. Q. What exactly are COX-2 inhibitors? A. COX-2 inhibitors do pretty much what their name implies – they inhibit a natural enzyme in our body called the clclooxygenase-2, or COX-2, enzyme. There are two COX enzymes – COX-1 and COX-2 and both complete several actions in our bodies. One very important action that both COX-1 and COX-2 enzymes share is the speeding up of our body’s production of prostaglandins. These hormone-like substances are made by the cells of the body and have several important functions. Some of the most powerful prostaglandins cause inflammation, pain, and fever when we are sick or injured. Prostaglandins also protect the lining of the stomach from the damaging effects of acid. Other prostaglandins make sure our platelets (important blood cells) make blood clots when needed. Still others help our kidneys get rid of unwanted salt and water. And researchers have just recently recognized the importance of still another prostaglandin that protects our heart and blood vessels. The NSAIDs reduce pain by reducing prostaglandin production by blocking or inhibiting the COX enzymes. In theory – less prostaglandins, less pain and welling seems reasonable. But if you really stop and think about it, it’s pretty easy to understand why this method of pain relief might result in significant consequences. Pain and inflammation are often needed for healing. And just as needed is the protection of our stomach lining, blood clotting ability, assisting kidney function, and keeping our blood vessels healthy. And scientists are beginning to understand if you interfere with one natural response, you may be disrupting the body’s ability to prevent extremes and imbalances. That’s why using aspirin and ibuprofen can result in stomach ulcers, kidney problems, and internal bleeding. And that’s why using synthetic COX-2 inhibitors can result in high blood pressure, blood clots, heart attacks, and strokes. Q. Why are we just now learning about the dangers of COX-2 inhibitors and other NSAIDs? A. That’s a good question! Many people over the age of 65 have chronic pain conditions and are frequent users of OTC and prescription NSAIDs. This age group also experiences heart disease and Alzheimer’s disease in greater numbers. So, if a 70 year old woman who’s been using Celebrex for the past two years for arthritis in her knees suddenly has a heart attack one morning, it would not be entirely unexpected. For the past five or six years, researchers have been studying the possibility that NSAIDs may prevent certain cancers, Alzheimer’s disease, and other health problems. The ongoing, close scrutiny of large group of people taking these medications by scientists who were conducting these studies has resulted in the discovery of these dangers. Q. What kind of natural compounds relieve chronic pain? A. There are many – glucosamine, Omega-3 fatty acids, the B vitamins – the list goes on and on. Instead of disrupting normal bodily responses, these natural compounds work in harmony with our body to eliminate chronic pain. Three very powerful and very effective all natural plant compound pain and inflammation relievers are Sweet Cherry, Boswellia serrata, and White Willow Bark. For many years there have been anecdotal or personal reports that claimed eating Sweet Cherries, specifically Prunus avium, wipes out back pain, arthritis, and gout. While anecdotal reports generally don’t account for much in the world of science, he sheer numbers of testimonials proclaiming the Sweet Cherry’s amazing ability to reduce pain made researchers sit up and take notice. When Sweet Cherries were examined in the lab, it was easy for scientists to understand how this natural fruit is able to relieve pain. It seems Sweet Cherry’s bright red color is the key. Like many deeply colored fruits, Sweet Cherries are full of flavonoids called anthocyanins and proanthocyanidins. These powerful plant compounds scavenge and destroy altered oxygen compounds called free radicals. Many degenerative, chronic diseases have been associated with the tissue damage caused by free radicals, including arthritis, heart disease, peripheral artery disease, and cancer. Cherry fruit extract is a natural anti-inflammatory compound, making it an excellent treatment for arthritis, fibromyalgia, and other chronic pain and inflammation diseases. A pain relieving plant compound that comes from the bark of a tree, Boswellia serrata has been used by Indian healers for hundreds of years to reduce painful inflammation. When 20th century researchers looked at extracts of Boswellia Gum Resin in the laboratory they discovered the presence of powerful plant compounds, called boswellic acids. Researchers found Boswellic Acids reduce inflammation in several ways. They open constricted blood vessels, improving blood flow to joints. They balance levels of leukotrienes – specific chemicals in the body that cause inflammation. And Boswellic Acids block two inflammatory chemicals that increase in asthma and inflammation of the colon. In addition to being helpful in treating these 2 illnesses, Boswellia has also been clinically studied and found to be quite effective in osteoarthritis and rheumatoid arthritis without any evidence of ulcers or stomach irritation. Another bark extract, White Willow Bark is one of the oldest and most effective pain relievers. For over 2,000 years extracts from the bark of the White Willow tree have been used to ease aches and pains and reduce fevers. It is the original source of aspirin, but when used as the entire plant medicine, White Willow Bark is much safer than aspirin and quite effective. White Willow Bark’s active ingredient is salicin and the combination of other compounds in the bark significantly enhances its pain killing power. In two large clinical trials of patients with chronic low back pain. White Willow Bark was found to be not only safer and much more effective than standard prescription therapies, it was also 40 percent more cost effective. Salicylic acid from White Willow Bark lowers the body’s levels of prostaglandins, easing both acute and chronic pain. White Willow Bark reduces the pain and swelling of arthritis, headache, back and neck pain, muscle aches, and menstrual cramps. But, unlike aspirin, it doesn’t cause stomach bleeding or other known adverse effects. Q. Do Sweet Cherry, Boswellic Acids, and White A. They do indeed. Because they reduce both pain and inflammation by a broad combination of actions, these natural extracts have been proven to be excellent against arthritis, back pain, and pain from inflammatory intestinal diseases (Crohn’s disease and ulcerative colitis), and would be expected to be helpful in most kinds of pain. Sweet Cherry, Boswellic Acids, and White Willow Bark relieve inflammation without causing stomach irritation, stomach ulcers, high blood pressure, blood clots, heart attacks, or strokes. That’s because these natural pain killers don’t disrupt the balance of enzymes or interfere with the body’s ability to prevent extremes and imbalances. However, as with any pain therapy, Sweet Cherry, Boswellic Acids, and White Willow Bark work best when they are used as part of a comprehensive treatment plan to relieve the most common underlying causes of chronic pain or SHIN. In addition, although these excellent natural remedies can often offer quick pain relief, natural remedies for severe chronic pains work best when they are given at maximum allowed doses and given 6 weeks to show their full effectiveness in combination with treating the pain’s underlying causes. The best chronic pain relief results when doctors and patients work together to meet the goals of treatment. Some important last notes: Many causes of chronic pain are serious and life threatening. Everyone who is living with chronic pain must consult their doctor or other healthcare practitioner to determine the reason for their ongoing discomfort. In other words – make sure you know why you are having chronic pain and what’s causing the pain you want to relieve. There are some types of chronic pain that only respond to opioids, or narcotic pain relievers. Morphine sulfate is an excellent pain medication and is used to relieve surgical pain, the pain of heart attacks, and pain from serious injuries. Morphine is also the very best drug for chronic cancer pain and non-malignant chronic pain. While many people fear opioids, these powerful pain killers can dramatically improve quality of life. If you are suffering with chronic cancer pain and you are hesitant to use morphine or another opioid, I urge you to discuss your concerns with your doctor other healthcare provider. No one with cancer should live with untreated or under-treated pain. Conclusion Even chronic pain can often be eliminated when SHIN is in combination with powerfully effective natural pain relievers. But, because some people may need to take pain relievers the rest of their lives, the medications they use must be safe as well as effective. The very safest come from natural plant compounds that have been studied for their ability to relieve chronic pain. You can become pain free and Sweet Cherries, Boswellic Acids, and White Willow Bark can help.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1503) Glucosamine Sulfate and Chondroitin Sulfate
Date:
March 28, 2007 11:10 AM
Glucosamine Sulfate and Chondroitin Sulfate Osteoarthritis is the most prevalent form of arthritis in the U.S., according to the Arthritis Foundation. One-third of all American adults have X-ray evidence of osteoarthritis of the hand, foot, knee, or hip. Osteoarthritis is responsible for more than 7 million physician visits per year and is second only to cardiovascular disease as the cause of chronic disability in adults. As Baby Boomers age, the number of people suffering from osteoarthritis is expected to rapidly increase in the next 10 years. While osteoarthritis research ahs led to the development of promising new prescription and over-the-counter medications aimed at reducing pain, none has created the excitement of glucosamine sulfate (GS), which actually addresses the underlying joint destruction. Q. What is osteoarthritis? A. Osteoarthritis is a complex, metabolic disorder of the cartilage and bones of certain joints. However, to fully understand how osteoarthritis develops, we need to understand how joints work. A joint is formed when two or more bones are brought together and held in place by muscles and tendons. Some joints have very little range of movement, such as the joints of the ribs, while others have much more range of movement. Hips, knees, elbows, writs, and thumbs are termed synovial joints, and have the greatest range of movement and mobility of human joints. To allow such mobility, synovial joints have a unique structure. The bones that form synovial joints are covered with cartilage. Tough fibrous tissue encloses the area between the bone ends and is called the joint capsule. The joint cavity within the capsule is lined with an inner membrane, called synovial membrane. The membrane secretes synovial fluid, a thick, slippery fluid that fills the small space around and between the two bones. This fluid contains many substances that lubricate the joint and ease movement. The cartilage of synovial joints serves two very important functions. First, it provides a remarkably smooth weight-bearing surface; synovial joints move easily. Secondly, synovial cartilage serves as a shock absorber, providing a soft, flexible foundation. Healthy cartilage absorbs the force of the energy, transmits the load to the bone, and distributes the mechanical stress created by joint movement. Synovial joints function under almost continual mechanical stress. A joint’s ability to withstand or resist this stress is a reflection of its health. When the mechanical stress is too great or the joint’s ability to resist this stress is compromised, physical changes occur in the cartilage covering the bones. Cartilage is a tough, elastic tissue, comprised mostly of water, collagen, and complex proteins called proteoglycans. In osteoarthritis, the cartilage starts to weaken, becomes frayed, and eventually breaks down. This exposes the bones of the joint, which then rub together. A gritty feeling and grinding sound may occur when an osteoarthritic joint is bent and flexed. As osteoarthritis progresses, bits of bone and cartilage often break off and float inside the joint space. The bones may enlarge, causing the joint to lose its normal shape. Tiny bone spurs may grow on the joints’ sides and edges. These physical changes in the diseased joint are responsible for progressive damage and continual pain. People with osteoarthritis most frequently describe their pain as deep and aching. The pain not only is felt in the affected joint but may also be present in the surrounding and supporting muscles. Joint inflammation also may occur, increasing the already considerable discomfort. Joint stiffness is another unfortunate component of osteoarthritis. Exercising the joint most often results in increased pain; however, stiffness tends to follow periods of inactivity. Humid weather often makes all osteoarthritis symptoms worse. As the disease progresses, the pain may occur even when the joint is at rest, creating sleepless nights and miserable days. Q. What causes osteoarthritis? A. Osteoarthritis’ exact cause remains unknown. Researchers know aging doesn’t appear to cause osteoarthritis. Cartilage in people with the disease show many destructive changes not seen in older persons without the disease. However, certain conditions do seem to trigger osteoarthritis or make it worse. Some families seem to have a lot of osteoarthritis, pointing to a genetic factor. This is most commonly seen in people who have osteoarthritis of the hands. Repeated trauma can contribute to osteoarthritis, too. Athletes, extremely active people, and individuals who have physically demanding jobs often develop the disease. Persons who have certain bone disorders are more prone to osteoarthritis due to the continuous, uneven stress in their hips and knees. Obesity also is a risk factor for the disease. In overweight women, osteoarthritis of the knee is fairly common. Excess pounds also may have a direct metabolic effect on cartilage beyond the effects of increased joint stress. Obese people also often have m ore dense bones. Research has shown dense bones may provide less shock-absorbing function than thinner bones, allowing more direct trauma to the cartilage. Q. Can osteoarthritis be prevented? A. While there is currently no sure way to prevent osteoarthritis or slow its progression, some lifestyle changes may reduce or delay symptoms. The Arthritis Foundation states that maintaining a healthy weight, losing weight if needed, and regular exercise are effective osteoarthritis prevention measures. Optimal calcium intake in younger years is vital to ensure a healthy aging skeletal system. Vitamins A, C, D, and E have been studied for their role in osteoarthritis prevention. These vitamins also have shown benefit in individuals who have osteoarthritis. Q. What treatments are available for osteoarthritis? A. The goal of treatment is to reduce or relieve pain, maintain or improve movement, and minimize any potential permanent disability. Typically, non-steroidal anti-inflammatory drugs or NSAIDs (pronounced “n-sayds”) such as aspirin and ibuprofen are used for pain and inflammation relief. These medications are effective in treating only the pain of osteoarthritis. These medications have many side effects, some of which are serious. NSAID-induced gastrointestinal complications cause more than 100,000 hospitalizations and nearly 16,500 deaths annually in the U.S. Aspirin can cause an extremely annoying and continual ringing in the ears. NSAIDs frequently cause damage to the stomach lining, which can produce uncomfortable heartburn and abdominal pain. Continued NSAID use may lead to the development of stomach ulcers. NSAID-related ulcers can perforate the stomach lining and cause life-threatening bleeding. Most NSAIDs also interfere with blood clotting and may cause kidney damage. When older persons take NSAIDs, dizziness, drowsiness, memory loss, and decreased attention span may occur. Acetaminophen (Tylenol and similar medications) is similar to aspirin and other NSAIDs in its pain-relief abilities. However, acetaminophen doesn’t reduce inflammation. And while acetaminophen doesn’t have the same side effects of aspirin and other NSAIDs, if large doses are taken, liver damage can occur. Newer medications called COX-2 inhibitors provide both pain relief and reduce inflammation without the many side effects of acetaminophen, aspirin, and other NSAIDs. More recent research has indicated that, in certain situations. COX02 inhibitors also can cause stomach lining damage and bleeding. While aspirin, NSAIDs, and COX-2 inhibitors may reduce osteoarthritis pain, they do nothing to stop or slow down cartilage deterioration. In other words, these medications have no effect on the disease itself. That is why many believe glucosamine sulfate (GS) and chondroitin sulfate (CS) are preferable to pain relievers and anti-inflammatory medications in osteoarthritis treatment: they actually improve synovial joint health. And they do this without potentially life-threatening side effects. Q. How do GS and CS work? A. GS improves the health of joints affected by osteoarthritis. This supplement is so effective that even physicians who mostly rely on conventional medications routinely recommend it to their patients with osteoarthritis. In fact, GS is so good at treating osteoarthritis, many physicians use it for their own osteoarthritis joints. There is even more good news. When glucosamine sulfate is combined with low-molecular weight CS, even greater benefits can be achieved. GS and CS are naturally occurring compounds found in human joints. The right GS/CS combination actually reverses damage in joints affected by osteoarthritis, in turn significantly reducing pain and stiffness. Glucosamine occurs naturally in the body and is found in synovial fluid. Glucosamine is a basic building block for proteoglycans, is a basic building block for proteoglycans, one of the important compounds of synovial cartilage. It also is required for the formation of lubricants and protective agents for the joints. In Europe, GS and CS have been used to treat osteoarthritis for more than 10 years. While persons with arthritis felt much better when they took GS and CS, no one really knew how these compounds worked. When European and American researchers first started to study glucosamine, they discovered GS can reduce synovial joint inflammation. This explains why people felt better after taking it. Q. What has additional study of GS and CS revealed? A. As the scientific study of GS progressed, researchers determined it can stimulate the growth of cartilage cells, inhibit proteoglycans breakdown, and rebuild cartilage damaged from osteoarthritis. In other words, GS does not simply make persons with osteoarthritis feel better; GS actually makes persons with osteoarthritis get better. GS is the form of glucosamine used in research. It’s the sulfate salt of glucosamine and breaks down into glucosamine and sulfate ions in the body. The sulfate part of GS plays an important role in proteoglycans synthesis. CS also provides cartilage strength and resilience. CS is an important component of the cartilage proteoglycans of synovial joints. Because CS helps the production of proteoglycans, researchers believe CS works in a similar nature to GS. Q. Couldn’t GS and CS be taken on their own? Is there any benefit in taking them together? A. Research has discovered GS and CS act synergistically (work well together) in improving joint health. Several studies have investigated this action and it’s recommended that GS and CD be taken together. However, there may be times when your healthcare practitioner may recommend using one or the other, but not both GS and CS together. Please follow their recommendations to obtain the best results for your own unique health concerns. Low-molecular weight chondroitin sulfate (CS) is the preferred CS form, and the form that has shown the most promise in studies. Q. Why is it important to take low-molecular weight CS? A. When CS was first studied, it was given to six healthy volunteers, six patients with rheumatoid arthritis, and six patients with osteoarthritis. Researchers then measured the levels of CS in all study subjects. They found no evidence of CS in any of the subjects. This single study led many physicians and scientists to believe CS can’t be absorbed, and was not an effective natural treatment. However, several other studies in healthy volunteers have reported CS can be absorbed. The distinct difference for these findings is thought to be associated with the types of CS used in the studies. Some forms are much more absorbable that others. This was demonstrated in a recent study using CS with lower molecular weight. A higher absorption is observed for low-molecular weight CS. This means CS products with a low molecular weight may be better absorbed, allowing the CS to get into the bloodstream and the synovial fluid of joints where it’s needed. Q. Are there other supplements that can help osteoarthritis? A. Several vitamins, minerals, enzymes, and natural supplements have benefits for individuals with osteoarthritis. Proteolytic enzymes effectively offer relief of the pain, stiffness, and swelling of osteoarthritis. Folic acid and vitamin B can reduce the number of tender joints and increase joint mobility. Vitamins C, D, and E not only may prevent osteoarthritis, but inhibit the disease’s progression. Niacinamide improves joint function, range of motion, and muscle strength. Clinical studies using the herb Boswellia serrata have yielded good results in osteoarthritis. Application of ointments on osteoarthritic joints may be helpful in reducing pain and stiffness. Menthol-based preparations can provide soothing relief to painful joints. Capsaicin ointments and gel made for cayenne pepper also are very beneficial. When applied to the skin, capsaicin first stimulates, then blocks, nerve fibers that transmit pain messages. Capsaicin depletes nerve fibers of a neurotransmitter called substance P. This neurotransmitter transmits pain messages and activates inflammation in osteoarthritis. Capsaicin ointment is very effective in relieving osteoarthritis pain in many individuals. Q. Is there anything else I can do for joint pain and stiffness? A. When osteoarthritis occurs in the hands, use of a paraffin dip can be very comforting. A licensed health care practitioner can provide information about how to safely use paraffin dips at home. Exercise is an excellent way to keep joints mobile, decrease pain, and increase body strength, too. Water aerobics also can reduce the pressure and stress on joints. The Arthritis Foundation strongly suggests making movement an integral part of your life. When you’re in less pain and have more energy, more range-of-motion, and a better outlook on life, you’ll reduce stress and be a much healthier person despite your osteoarthritis. One important last thought When we don’t feel well, we sometimes have a tendency to self-diagnose. If you haven’t been evaluated by a licensed health care practitioner for your joint pain and stiffness, you need to do so. These symptoms may be caused by other illnesses and may require much different treatment. Only licensed health care practitioner can provide a certain diagnosis of osteoarthritis. Conclusion Osteoarthritis may be a part of life for many of us as we age; however, constant pain and stiffness need not be. GS combined with absorbable CS can actually improve damage in joints affected by osteoarthritis and significantly reduce pain and stiffness. And it can be an empowering way to improve your health. Buy Glucosamine and Chondroitin Sulfate at Vitanet ®, LLC
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1500) Benefits - Supports joint function and tissue health*
Date:
December 11, 2006 03:46 PM
To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage. Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3 Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3 Promotes optimal joint comfort, function and flexibility* Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4 Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7 Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8 Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11 Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results. Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption* Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14 Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability. Sustained Release – For lasting joint comfort and convenient dosing To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day. Safety Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.
Scientific References 2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68. 3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149. 4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7. 5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146. 6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002. 7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5. 8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers. 9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46. 10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7. 11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308. 12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34. 13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232. 14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J. 15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1438) Improove Memory ...
Date:
June 09, 2005 05:49 PM
Mesmerizing Memory by Cal Orey Energy Times, January 1, 1999 In the 60s, the same rock 'n' rollers who belted out "One pill makes you larger and one pill makes you small," often espoused the belief that certain pills could expand the mind. While counter-culture pill purveyors were pilloried for their pill-popping claims, 90s nutritional research has uncovered a stash of supplements that may amplify mental improvement. Like a blues singer bending a high note, researchers are now humming with dramatic assertions that certain nutritional supplements can sustain and enhance concentration and memory function. For instance, studies reveal possible benefits for cognitive powers from vitamin C, magnesium and Ginkgo biloba. A recent report in the Journal of the American Medical Association (JAMA 278:1327-1332) said that an extract of Ginkgo biloba "can stabilize and, in some cases, improve the cognitive function and social behavior of demented patients." A researcher in the Proceedings of the National Academy of Sciences noted that a daily dose of vitamin E may "help protect the brain and its memories from the ravages of time." And the beat goes on: other evidence indicates that zinc, iron and boron may pump up short-term memory attention span and cut the time it takes to perform mental tasks.
Neuronutrients Lester Packer, PhD, professor of molecular and cell biology at UC Berkeley, told a joint 1996 United Nations-World Health Organization conference on Aging that "there is a growing body of evidence indicating that the free radical theory of aging and aging-related disease is valid," and that dietary and supplemental antioxidants can help fight illness and mental deterioration. Vitamin E and other memory aids are believed to protect brain chemicals called neurotransmitters, "the ferrymen of the brain's communication system," that influence concentration and memory. Experts say that sustaining the level of these nerve chemicals in the brain can potentially improve all mental processes.
Brain Well-Being Too much alcohol, for example, commonly causes progressive mental decline, according to Secrets of the Superyoung (Villard) by David Weeks and Jamie James. The authors also point out that "the memory tends to worsen noticeably after 15 years of alcohol drinking, and much sooner in people who go on massive binges." "The effects of cigarette smoke are subtler because the poisonous effects of carbon monoxide in each puff are temporarily offset by the alerting effects of the nicotine," they add. Can't remember the name of that singer cavorting in a music video? Tests have shown that smokers are worse at connecting peoples' names to their faces than nonsmokers.
Cognition Ignition n Learn something new: A second language, musical instrument, or unique puzzles and games keep neurons working like new. n Turn off the TV: Read. Studies show that passively watching TV requires less concentration than eating cereal. Mental rejuvenation also requires physical activity. Exercise increases oxygen flow to the brain, which supports memory, concentration and cognition. One study has shown that exercise significantly brightened the moods of middle-aged and older women, regardless of whether they were pre- or post-menopausal, with or without hormone replacement therapy.
Supplemental Brain Help Antioxidants, including the previously mentioned vitamin E (You haven't forgotten vitamin E already, have you?), provide crucial help for vigorous cerebral function. The free radicals created by tobacco smoke, air pollution, ultraviolet light and certain carcinogenic chemicals deconstruct cell membranes and may foster microscopic brain cell havoc. Antioxidant enzymes convert free radicals to more neutral, benign substances and nutritional antioxidants can neutralize free radicals by linking up with them. Vitamin C, a brainy antioxidant all star, performs so well that, according to Dr. Khalsa, its levels in the brain are almost 15 times higher than in other parts of the body. This nutrient, he asserts, aids mental and physical longevity. In a UCLA study, people who ingested at least 300 mg of vitamin C daily lived more than six years longer than those who ingested less.
Mental Fat Added to this mix, magnesium also scavenges free-radicals, according to Dr. Khalsa. Plus, experts recommend grape seed extract (phytochemicals that protect a wide range of cellular structures) to safeguard nerve cells and mental capacity.
B Vitamins for the Mind
Iron Mind Boron plays a crucial part in mental function. Scientists at the USDA's Human Nutrition Research Center have linked boron deficiencies to chronic lethargy and fatigue. In brain studies, they found that the electrical activity of the gray matter in the boron deficient indicated increased drowsiness and mental sluggishness.
Huperzine Boost HupA basically protects the brain from free radical damage (due to low levels of antioxidant defenses) and maintains or enhances crucial neurotransmitter action. More specifically, HupA helps reduce the breakdown of acetylcholine, the vital neurotransmitter, and makes this substance more bioavailable. In addition, HupA helps make choline accessible to the brain for the synthesis of acetylcholine, according to a study in Neuropharmacology (30, 1991: 763-768). Normally, the brain manufactures sufficient levels of the chemical phosphatidylserine, a lecithin-derivative that helps boost neurotransmitter release, but deficiencies of vitamin B12 and folic acid, or of essential fatty acids, may retard that production. Low levels of phosphatidylserine in the brain are related to impaired mental function and depression in the elderly. Scientists reporting in Aging (5, 1993; 123-33) describe "good results" using phosphatidylserine in the treatment of age-related cognitive ills.
Ginkgo Brain Power Another ingredient in what seems like an alphabet-soup of brain nourishment is DHA (docosahexaenoic acid), an omega-3 fat essential for normal brain function. Researchers met recently at The New York Hospital-Cornell Medical Center's Nutrition Information Center to discuss "Keeping Your Brain in Shape: New Insights into DHA." Their findings revealed links between low levels of DHA and Alzheimer's, depression, memory loss, attention-deficit/hyperactivity disorder (ADHD) and certain behavioral traits including aggression and hostility.
Mostly Fat Researchers from the National Institutes of Health point out, however, that fish is an excellent dietary source of DHA. In their studies, they discovered that depression rates in Japan and Taiwan, where fish ranks a top spot on the menu, are significantly lower than in North America and Europe. DHA also is crucial to the neurological development of children, according to findings published in Pediatrics (vol. 101, no. 1, January 1998). Researchers suggest that DHA-rich breast milk should be the model for infant formulas that enhance babies' neurological development. Scientists also have correlated some behavioral problems in children-ADHD, for example-to DHA deficiencies. If you are a vegetarian, or have other cause for concern about a potential lack of DHA in your diet, you can rely on dietary supplementation of DHA. Bruce J. Holub, PhD, of the University of Guelph in Canada provided vegetarians in his research project with DHA supplements over a 42-day period and substantially increased their DHA blood levels. The bottom line to enhanced mental performance is to take a balanced approach, says Robert Snider, MD, who specializes in preventive medicine in Massena, New York. "Maintaining brain power includes exercise, stress reduction and good nutrition." The message to keep in mind: Don't lose your nutritional balance or you could lose a piece of your peace of mind. Recommended Reading: & Brain Builders (Reward Books, 1995), by Richard Leviton. Brain Longevity (Warner Books, 1997), by Dharma Singh Khalsa, MD. Omega 3 Oils to Improve Mental Health, Fight Degenerative Diseases and Extend Life (Avery, 1996), by Donald Rudin, MD, and Clara Felix. Successful Aging (Pantheon, 1998), by John W. Rowe, MD, and Robert L. Kahn, PhD.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=261) GlucosaMend™ Tissue/Joint Repair Complex
Date:
June 02, 2005 11:19 AM
More than 40 million Americans experience joint discomfort. But exciting new research proves you can do something about it. Our health and well-being is inextricably linked to lifestyle choices: the right combination of exercise, weight training and supplementation can strengthen muscles and joint tissues to minimize stress and degradation. Targeted nutrition to the multiple body systems related to joint and connective tissue can help maintain flexibility and joint comfort. GLUCOSAMEND supports the musculoskeletal system with structural building blocks and tissue production cofactors, as well as aiding the body’s mechanisms for soothing relief and antioxidant defense. Bio-Aligned Formula™ GLUCOSAMEND is uniquely effective because it is a Bio-Aligned Formula. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance. Musculoskeletal System—Structural Building Blocks Certain building blocks of joints and connective tissue can help maintain joint integrity and comfort. Glucosamine is a major constituent of glycosaminoglycans, which in turn form proteoglycans, molecules that hold and bind the water that lubricates joints, disperses stress and nourishes joint tissue. The amino acids proline and lysine are structural components of collagen and elastin, which give strength to connective tissue. GLUCOSAMEND contains glucosamine sulfate, N-acetyl glucosamine, proline and lysine. Musculoskeletal System—Tissue Production Cofactors Some micronutrients are necessary as cofactors in the production of connective tissue. For example, vitamin C and copper help form hydroxyproline and hydroxylysine, main constituents of collagen. A unique property of grape seed extract is its ability to form a bond between broken collagen fibers, helping to repair them and restore flexibility and strength to connective tissues and joints. GLUCOSAMEND provides vitamin C, zinc, manganese, copper, and grape seed extract to address these cofactors. Soothing Relief Mechanisms Some herbs and nutrients have the capacity to support the body’s natural mechanisms for increasing comfort. Boswellia, for example, is an herb with soothing properties, while vitamin B-6 helps to stabilize collagen and elastin. Additional herbs and nutrients, acting in conjunction with antioxidant protectors, support tissue comfort and health. GLUCOSAMEND contains Boswellia serrata, quercetin, copper, and vitamin B-6. Antioxidant Defense The health and integrity of joints and tissues—specifically of cell membranes— is supported by botanicals and nutrients that support the body’s natural antioxidant response. When tissues become damaged, the body mounts a repair process that ultimately generates free radicals. These free radicals can also break down healthy cells and tissues in the process, hence the need for antioxidants to neutralize and break the cycle. GLUCOSAMEND provides grape seed extract, vitamin C, zinc, selenium, copper, quercetin to neutralize free radicals. Lifestyle Tips for Healthy Joints: A Strategy for WellnessSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Source Naturals believes in a holistic approach to living. Not only can supplements bring balances to your individual body systems but certain lifestyle choices can also bio-align your health. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, limit saturated fat and eliminate hydrogenated oils. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAME, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CHONDROITIN to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage. Structural Building Blocks N-Acetyl Glucosamine, Glucosamine Sulfate, L-Lysine, L-Proline Tissue Production Cofactors Grape Seed, Copper, Manganese, Zinc, Vitamins A, B-6 and C, Niacinamide Soothing Relief Mechanisms Boswellia Serrata, Quercetin, Turmeric, Copper, Magnesium, Zinc, Vitamin C Antioxidant Defense Grape Seed, Quercetin, Manganese, Selenium, Zinc, Vitamins A, C and E
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=152) |