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six top-notch supplements that can help you achieve your goals. Darrell Miller 12/6/23
Congress Gives Jeff Sessions $0 To Go After Medical Marijuana Laws Darrell Miller 5/9/17
Possible new head of the FDA is a supporter of medical marijuana … Could Trump's FDA finally stop suppressing cannabis? Darrell Miller 2/4/17
Heart disease protein could be connect to brain damage: Study Darrell Miller 12/16/16
Here's How the Food Lobby Affects What We Eat Darrell Miller 11/26/16
What Is Patchouli Oil? Darrell Miller 2/22/14
How Does Phosphatidyl Serine Improve Your Health? Darrell Miller 4/17/12
Advocacy Update Darrell Miller 5/17/08
CLA and the Catabolic Cascade Darrell Miller 6/22/05
Fats for Life - the quality of the fat you eat is probably much more important than the... Darrell Miller 6/12/05
Summer Sports Nutrition Guide Darrell Miller 6/11/05
GABA to improve memory ... Darrell Miller 5/23/05




six top-notch supplements that can help you achieve your goals.
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Date: December 06, 2023 04:55 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: six top-notch supplements that can help you achieve your goals.

If you're looking to stay in the game longer and improve endurance while promoting rapid recovery, we've got you covered! six top-notch supplements that can help you achieve your goals.

For most of us, life can feel like quite the balancing act. In an ideal world, we would all have ample time throughout the day to dedicate to our health and well-being. However, reality paints a different picture, where 24 hours can seem like an insufficient amount of time to squeeze in work, school, family, and the countless responsibilities that life throws at us. In recent years, the use of supplements for recovery has gained popularity, becoming more common than ever before.

Our bodies face a barrage of daily stresses, including exposure to environmental toxins, electromagnetic pollution, and the strain of intense physical activity. These factors increase our body's demands for antioxidants and essential nutrients that aid in the process of recovery. While consuming antioxidant-rich foods can certainly make a difference, it can be challenging to meet these requirements solely through our diet. That's where a well-rounded supplement regimen can play a crucial role in promoting optimal health and aiding in recovery. Even with our best efforts to exercise regularly, eat nutritious meals, and get sufficient sleep, life in the 21st century can be incredibly demanding, depleting our bodies on a cellular level.

For athletes, consistent training is key to reaching desired performance levels. It's important to understand that the muscle recovery and building process primarily occurs between gym Sessions. Developing a comprehensive recovery strategy during this crucial window, through the use of supplements, proper nutrition, and adequate rest, can help athletes perform at their best week in and week out. Failing to make the most of this recovery period may result in free radical damage and delayed onset muscle soreness (DOMS). To maximize the benefits, it's important to prioritize food as the primary source of vital nutrients, while also recognizing the significant role supplements can play in providing the necessary building blocks for muscle repair due to their rapid absorption rate. However, it's essential to ensure that any chosen supplements are clinically validated, demonstrating efficacy and supported by solid scientific evidence.

In today's fast-paced world, there is a growing demand for quick and convenient solutions to jumpstart the recovery process. Nevertheless, when it comes to choosing supplements, it's important to remember that one size does not fit all. The market offers an overwhelming array of options, often leaving individuals feeling bewildered about which products to select.

Before diving into my recommendations for the top six supplements to aid in recovery, I believe it's crucial to emphasize the significance of cellular renewal and its direct impact on the recovery process. This, in my opinion, serves as the key to achieving a quick and effective recovery.

Oxidation and Free Radical Damage

A fundamental key to staying young and maintaining optimal health is cellular renewal and minimizing the damage to cells over time. We all age, but studies have shown that some individuals age better than others. Have you ever wondered why? Well, recent research has linked oxidative stress to the aging process. So, what exactly is oxidative stress? Allow me to explain in simple terms – oxidation occurs when the body produces by-products commonly known as free radicals. It's almost like a machine rusting, but instead of rust forming on iron, our bodies experience the effects of aging and age-related diseases.

Now, our bodies naturally produce free radicals as part of our daily metabolism, and they can also be produced as a result of environmental pollutants from everyday things like air, water, and even sun exposure. As we age, our bodies become more vulnerable to the long-term effects of oxidative stress, which simply means we accumulate too many free radicals and experience increased inflammation at the cellular level.

As interesting as it may sound, the process of oxidation is actually abundant and can be beneficial for our bodies to function properly. But, and this is an important "but," this very process can also cause potential harm. You see, the oxidizing process creates these molecules called free radicals, which are electrically charged. These free radicals interact with our cells, and this interaction can lead to both positive and negative outcomes. For example, our immune system utilizes free radicals to help fight infection. However, when LDL cholesterol (often referred to as bad cholesterol) is oxidized, it can become a concern (cholesterol buildup).

Let's talk about oxidative stress. It occurs when the level of free radicals overwhelms the body's natural antioxidant defense system, resulting in cell damage. As I mentioned earlier, while free radicals serve useful functions in the body, they are highly unstable molecules. If they remain uncontrolled, they have the potential to wreak havoc by causing damage to cells, enzymes, and even our DNA, which ultimately accelerates the aging process. In addition, these free radicals can also contribute to the development of various age-related diseases, including arthritis, cancer, and heart disease

Now, inflammation is triggered by free radical damage, and it is this inflammation that leads to the negative effects of free radicals due to oxidation. The question then becomes, how can we address this in our daily nutritional regimen? The answer lies in the incorporation of antioxidants, which play a vital role in combating oxidative stress and minimizing the damage caused by free radicals in our bodies. You'll be glad to know that there are foods rich in antioxidant content that can help us on this journey. In fact, certain foods contain phytonutrients that, according to many health professionals, hold the potential to unlock the secrets of longevity and overall well-being.

So, my dear friend, let's take a proactive approach, nourish our bodies with antioxidant-rich foods, and strive to minimize the effects of oxidative stress caused by free radicals. It's never too late to make positive choices for our health and age gracefully.

Phytonutrients, also known as health boosters, are substances produced by plants to protect themselves from harmful bacteria and viruses. However, these compounds also offer significant benefits to the human body. Packed with essential nutrients, phytonutrients play an active role in promoting good health. They belong to the antioxidant family, responsible for eliminating harmful free radicals and thus slowing down the aging process. Incorporating a diet rich in high antioxidant foods like fresh fruits and vegetables is crucial as the first line of defense against aging.

While vitamins A, C, and E are commonly known antioxidants, there are other antioxidants available in both food and supplement form. These antioxidant supplements play a vital role in bridging the nutritional gap left by processed foods, lacking the necessary antioxidants and nutrients to combat free radicals effectively.

Let's take a closer look at my top six supplement recommendations, known for their efficacy in fighting oxidative stress and promoting optimal recovery:

Beta Alanine: As an amino acid derivative, Beta Alanine is proven to enhance intramuscular carnosine content, improving the body's ability to buffer hydrogen ions. During exercise, the body accumulates hydrogen ions, contributing to fatigue and lowering pH levels. Beta Alanine supplementation can reduce fatigue, enhance exercise performance, and increase training volume. Whether it's interval training or weightlifting to improve running economy, incorporating beta-alanine can have a positive impact on endurance performance and overall training results.

BCAAs: Branched Chain Amino Acids (BCAAs) have become a staple supplement for athletes due to their role in muscle and energy production during exercise. Consisting of three essential amino acids - leucine, isoleucine, and valine - BCAAs have been shown to significantly reduce muscle soreness and expedite the recovery process. Supplementing with BCAAs helps prevent muscle breakdown, as the body does not need to rely on its own muscle tissue for energy. Consequently, protein synthesis remains high, supporting muscle growth and repair.

Creatine, a natural molecule found in muscle cells. When engaging in high-intensity workouts like weightlifting, Creatine helps your body produce adenosine triphosphate (ATP), a vital energy source. This amazing compound improves strength, boosts lean muscle mass, and aids in faster muscle recovery.

Flavonoid Root, a breakthrough extract known for its cardiovascular benefits. This extract is packed with potent antioxidants and acts as a nitric oxide booster, promoting increased endurance during workouts. Studies have shown that it fights against free radical damage and increases the flow of oxygen-rich blood, ensuring optimal cardiovascular health. You can also boost nitric oxide with beet root, and l-citruline.

Speaking of studies, a published research paper in Food and Nutrition Research (April 2016) highlighted the effects of the unique flavonoid root extract on arterial health. The study revealed that after one year of consumption, participants experienced a decrease in artery wall thickness, total cholesterol, LDL levels, and blood pressure. This indicates that the extract may help reduce the risk of oxidation-related cerebral vascular issues and improve overall cardiovascular health

Glutamine. It's the most abundant amino acid in the human body and plays a vital role in muscle recovery and repair. Glutamine aids in preventing muscle soreness, optimizing post-workout recovery, and supporting muscle rebuilding. By facilitating nitrogen transport, regulating acid-base balance, and acting as an antioxidant, Glutamine ensures faster post-workout muscle recovery, giving you the freedom to train harder for better results.

Protein plays a crucial role in replenishing and repairing your muscles after a workout, making it a key nutrient to consume alongside carbohydrates. By opting for a protein shake as a post-workout option, you can efficiently supply amino acids to your muscles, stimulating muscle protein synthesis, enhancing recovery, and promoting growth. It's important, though, to choose a protein shake that contains high-quality ingredients, as prioritizing quality over quantity is key when it comes to protein.

Apart from protein, there are several other supplements that work through various mechanisms to provide natural, broad-spectrum antioxidant and nutrient support, ultimately contributing to optimal health and recovery. Taking preventative measures to protect the health of different body systems is much easier than trying to restore their function after damage has occurred. With this in mind, retailers should suggest a preventive program to their customers, aiming to limit free radical damage and promote recovery. As the adage goes, "an ounce of prevention is worth a pound of cure," emphasizing the significance of protecting and preserving one's health.

In conclusion, the role of antioxidants, particularly phytonutrients, in maintaining overall health and combating oxidative stress cannot be overstated. These beneficial compounds not only slow down the aging process, but also enhance the body's ability to recover from physical exertion. Various supplements, including Beta Alanine, BCAAs, Creatine, Flavonoid Root, Glutamine, and Protein, each offer distinct benefits in supporting muscle growth, improving athletic performance, and promoting quicker recovery. The incorporation of these supplements into one's regimen can effectively bridge the nutritional gap left by processed foods. A preventive strategy, emphasizing a diet rich in antioxidants and high-quality supplements, holds the key to optimal health and longevity. As the saying goes, 'an ounce of prevention is worth a pound of cure'.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6591)


Congress Gives Jeff Sessions $0 To Go After Medical Marijuana Laws
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Date: May 09, 2017 10:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Congress Gives Jeff Sessions $0 To Go After Medical Marijuana Laws





Erin Elizabeth summarizes the current political climate as it relates to medical marijuana and the prevailing opinion of lawmakers on Capital Hill. Attorney General, Jeff Sessions, has consistently expressed an emphatically negative view of medical marijuana and has expressed interested in addressing users from his position in the federal government. However, congress, who are simply honoring the wishes of the voters in their home states, have allocated no money to sessions in this effort, solidifying the federal government’s actual stance on medical marijuana: States have the rights to make their own rules and laws to govern the use of this substance for medical purposes.

Read more: Congress Gives Jeff Sessions $0 To Go After Medical Marijuana Laws

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Possible new head of the FDA is a supporter of medical marijuana … Could Trump's FDA finally stop suppressing cannabis?
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Date: February 04, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Possible new head of the FDA is a supporter of medical marijuana … Could Trump's FDA finally stop suppressing cannabis?





Back on November 8th 2016 there was much celebration among the marijuana community. There were four more states that legalized adult use cannabis and several, including Florida, that legalized medical marijuana.  However, there was still a lump in the back of many of our throats.  Sessions has a long standing anti-drug stance and has made some strong comments against cannabis legalization. Recently the Trump administration has made a surprising announcement when they confirmed previous reports that Jim O'Neil is being considered to lead the Food and Drug Administration.

Key Takeaways:

  • For decades, cannabis advocates have pushed for universal legalization of medical marijuana. Citing scientific study after scientific study, they have forcefully (and truthfully) argued that legalization would provide much needed relief to millions of people suffering from a host of medical ailments.
  • But the federal government has only responded with continued bans and regulatory restrictions that have limited access to the many who wish to freely choose this alternative medical treatment. In fact, the Drug Enforcement Agency (DEA) has now technically reclassified cannabis extracts as a Schedule I substance, putting them in the same category as heroin.
  • Now, however, the nightmarish over-regulation of cannabis may be about to be dismantled. President Donald J. Trump may be about to nominate someone to head up the Food and Drug Administration who believes in, and is a fan of, medical marijuana. (RELATED: Discover the latest scientific data on cannabis, hemp and marijuana at HempScience.news)

"For decades, cannabis advocates have pushed for universal legalization of medical marijuana. Citing scientific study after scientific study, they have forcefully (and truthfully) argued that legalization would provide much needed relief to millions of people suffering from a host of medical ailments."



Reference:

//www.naturalnews.com/2017-01-29-possible-new-head-of-the-fda-is-a-supporter-of-medical-marijuana.html

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Heart disease protein could be connect to brain damage: Study
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Date: December 16, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Heart disease protein could be connect to brain damage: Study





Women over the age of 50 who follow a high-protein diet could be at higher risk for heart failure, especially if much of their protein comes from meat, according to preliminary research presented at the American Heart Association's Scientific Sessions 2016. Researchers evaluated the self-reported daily diets of 103,878 women between the ages of 50 and 79 years, from 1993 to 1998. A total of 1,711 women developed heart failure over the study period.

Key Takeaways:

  • According to a new study, the level of a certain protein in the blood is linked to heart disease and early stage brain damage.
  • The study shows that the presence of NT-proBNP in the blood is indicative of sub-clinical heart disease and brain diseases like strokes or dementia.
  • Further research, including follow-up brain MRI studies and measurements of NT-proBNP, is needed to better understand the relationship.

"The study, published online in the Journal of Radiology, has said that a substance or marker in the blood is indicative of sub-clinical heart disease and brain diseases like a stroke and or dementia, and could speed up initiation of treatments and lifestyle changes, potentially slowing or even reversing the disease’s course."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.hindustantimes.com/health-and-fitness/heart-disease-protein-could-be-connect-to-brain-damage-study/story-t0pDSjXmMHRvFGnridyENO.html&ct=ga&cd=CAIyGjFmZmViMTExOGM5Mzg5YTQ6Y29tOmVuOlVT&usg=AFQjCNGitbxGFiZpCbRhb9ozY4qbFpilxw

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3655)


Here's How the Food Lobby Affects What We Eat
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Date: November 26, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Here's How the Food Lobby Affects What We Eat





Most people believe that fresh fruits and vegetables are the best choice for healthy food. Recent conferences with dieticians have been focusing more on prepackaged food as a healthy choice. Large companies at the conferences, such as Nabisco and PepsiCo, are trying to market their brands in a more healthy light. Many of these companies that are known for their less- healthy and high sugar products are trying to change the consumers’ views of them.

Key Takeaways:

  • "Newtons are made with real fruit and whole grains. True or false?" a Nabisco representative asks onlookers, who are among 10,000 attendees at a conference where dietitians can earn credits for continuing education.
  • While the influence of food corporations on the Academy of Nutrition and Dietetics and its 75,000 members has come under greater scrutiny, some see growing sensitivity to ethical and conflict-of-interest issues.
  • The academy noted that Sessions sponsored by companies or industry groups were distinct from regular educational Sessions because they required a $10 donation from session attendees to the academy's foundation, which provides scholarships and research grants. The sponsored Sessions still count toward continuing education credits, which are required to maintain licenses.

"Among the hundreds of exhibits, many focused on items like beans, eggs, strawberries and leafy greens."



Reference:

//www.nbcnews.com/health/diet-fitness/how-food-lobby-affects-nutrition-advice-n676266?cid=public-rss_20161101

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3512)


What Is Patchouli Oil?
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Date: February 22, 2014 08:12 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Patchouli Oil?

What is patchouli

patchouli plantPatchouli oil is normally distilled from the flowers and leaves of a plant known as Patchouli, a bushy herb which is native in Asian. It is famous for its beautiful scent and has been used in perfumes for centuries. It is recently used as an alternative herbal medication for chronic diseases as well as an insect repellent.

Health benefits of patchouli

Patchouli oil offers several health benefits including treating digestive conditions such as diarrhoea, nausea and vomiting, prevention of wrinkles, speeding healing of wounds and disappearance of bruises, fighting infection and healing snake bites. Elements of patchouli oil are found in many beauty and skin care products. Patchouli oil is very ornamental in preventing anxiety as well as a wide variety of allergies. It is used in herbal curing of hypertension, haemorrhoids, fluid retention and weight reduction. It is one of the major ingredients for treatment of depression.

When patchouli oil is applied undiluted on the skin, it can improve the skin condition by smoothening sagging and chapped skin. It clears dandruffs on the head and deals with skin undesirable conditions such as acne, dermatitis and eczema. The oil is also used to reduce stress in therapeutic and aroma therapeutic healing. It contains several desirable properties including being anti- inflammatory, antifungal, relaxant, stimulant and insecticidal, a digestive aid, diuretic, tonic, decongestant, deodorant, anti-infectious, antiseptic, antimicrobial and antitoxic. It is one of the most widely used products in medicine development.

Patchouli oil is naturally sweet and attractive to use. It offers an inspiring scent that feels very sweet. Its influence is known to relax both the body and the mind. It has been used in spiritual healing for hundreds of years. It is used to align the heart chakra with the sacral and root chakras. In meditational healing, it helps people release insecurities, obSessions, and jealousness while enhancing one’s desire for a satisfying and fuller life.

Sources

  1. //www.experience-essential-oils.com/patchouli-oil.html
  2. //en.wikipedia.org/wiki/Patchouli

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How Does Phosphatidyl Serine Improve Your Health?
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Date: April 17, 2012 07:22 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Phosphatidyl Serine Improve Your Health?

Health Benefits Of Phosphatidyl Serine

Phosphatidyl serine is phospholipid that is vital to your brain functioning. The phospholipid are molecules containing both fatty acids and amino acids found in every cell in the body. Phodphatidyl Serine supplements are plant extracts that has been proven safe and effective therapeutic substance in remedying memory disorders as well as in enhancing higher brain functions. Clinical trials have shown that this vitamin supplement do strengthen your memory, increase mental acuity, increase concentration, boosts learning, enhances attention and vigilance. In addition, Phodphatidyl serine relieves depression while improving your mood and inhibits increases in cortisol induced by exercise and stress.

The supplement works by enabling your brain cells to metabolize glucose and releases it to bind with neurotransmitters which hence support learning, memory and other cognitive functions. Phodphatidyl serine enhances the cells communication in the brain through increasing the number of membrane receptor sites. It is also important to note that this natural supplement modulates the fluidity of the cell membranes which are essential in supporting the ability of brain cells to send and receive chemical communications.

Health Benefits

Another health benefit associated with Phodphatidyl serine is its ability to restore the supply and output of acetylcholine in the brain. Acetylcholine is an essential transmitter to memory and is associated in reversing aging. Further, it increases the availability of endogenous chlorine used for de novo synthesis and production. Patients diagnosed with clinical depression that have ben put under the treatment of Phodphatidyl serine have registered a remarkable improvement with their symptoms. This follows from the fact that the supplement stimulates the production of dopamine by the brain. A deficit in dopamine in the brain has also been associated with attention deficit disorder and hence the natural supplement of Phodphatidyl serine has demonstrated to be an effective remedy for the disorder.

Weight Training

Research indicates that athletes involved in weight training, endurance running and cycling can reduce muscle soreness when they use Phodphatidyl serine. The athletes on this supplement have also been reported to undergo speed recovery during their rigorous training Sessions. Other benefits of the supplement include; testicular function, formation of bone matrix, heart beat coordination, cell repair and removal by the immune system and secretion of hormones by the adrenal glands.

Stress

It is vital to note that phodphatidyl serine is present in almost every cell in our body and the membrane proteins it activates are important in all these cells. However, our bodies cannot produce enough amounts of it when under stress, when there is a deficit in necessary enzymes and metabolic cofactors, and when aged. Stress increases the demands for phospatidylserine thus depleting the available levels in the cells. On the other hand, aging not only increases the brain's requirement for phosphatidylserine but also leads to inefficiency in the digestive and metabolic functions of the body. This makes it difficult for aged people to acquire enough of it from the diet and thus it is recommended that aged people should use phosphatidyl serine supplements.

Modern diets with low fat and low cholesterol levels have been shown to be lacking in phodphotidyl serine to levels of up to 150 mg per day. A vegetarian diet on the other hand may have a deficit of up to 250 mg per day. This deficit in supply of Phodphatidyl serine in the diet leads to impairment of your brain's ability to form, store, process and even remember. It is vital hence to consider taking vitamin supplements with phosphatidyl serine to cater for the deficit which may be detrimental to your health.

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Advocacy Update
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Date: May 17, 2008 10:17 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Advocacy Update

Recently, the Natural Products Association has experienced a flurry of activity on the legislative front. One month ago, Natural Products Association members went to Washington, D.C. to meet with their representatives and discuss legislation important to the association and the industry. Many who could not visit Washington in person were part of our "virtual march" on Washington that delivered e-mails, petitions, and videos to Congress on the importance of natural products. Natural Products Day was a great success, boasting higher than ever attendance at our evening Congressional reception, and resulting in additional co-sponsors for S. 771, the Child Nutrition Promotion and School Lunch Protection Act sponsored by Tom Harkin (D-Iowa). The bill now boasts co-sponsorship of more than a quarter of the Senate. Its companion bill in the House of Representatives, H.R. 1363, sponsored by Lynn Woolsey (D-Calif.), has gained an additional five co-sponsors as the result of Natural Products Day meetings and now has 140 co-sponsors. These bills continue to build momentum, thanks to your support.

More recently, the Natural Products Association urged supporters to contact their legislators to include an amendment to the "Farm Bill" allowing food stamp recipients to purchase dietary supplements. This provision was similar to free-standing bills that have been introduced in the current and previous Congresses by Sens. Harkin and Orrin Hatch (R-Utah) and have earned the association's support. Although the amendment advanced further than other versions in previous Sessions, it did not make the final Farm Bill, which was reported out of conference today. The good news is that the Farm Bill did contain significant increases in nutrition programs and increased funding for organic farming, another supported goal of the Natural Products Association. Because of the strong effort of our supporters on the amendment's behalf, the bill was placed on Congress's radar screens and has greatly improved the chances as stand-alone legislation, S. 770, the Food Stamp Vitamin and Mineral Improvement Act, of seeing passage. We will continue to ask for support on this important bill as this legislative session progresses.

In addition, the Natural Products Association has been leading the fight to protect Dehydroepiandrosterone (DHEA), and to keep this important, safe, and effective supplement available to elderly consumers. The same players behind S. 762, which would wrongly classify DHEA as an anabolic steroid, proposed S. 2470 in late 2007 as a misplaced reaction the release of the Mitchell Report, which chronicled the abuse of steroids by professional baseball players. Although DHEA has no performance enhancing attributes, this bill was proposed to limit the access of minors to DHEA. The Natural Products Association and its supporters have worked hard to inform Congress of the benefits of DHEA, and that it is not an anabolic steroid and should not be classified as one. We have been able so far to prevent any movement on the bill, but the association continues to monitor its progress and make sure that this supplement remains accessible to the seniors who need it most.

Thanks to your help, the Natural Products Association continues to have an active presence on Capitol Hill that is felt by legislators. We could not do it without the help of you, our supporters, who know how important it is to stand up for natural products. The impact of your messages to legislators continues to help the Natural Products Association to ensure all natural products - from natural and organic foods to dietary supplements and health and beauty aids - are accessible to Americans. With your continued support we will continue to be known as a vocal group with a wide base of support through the rest of this legislative session and beyond.

To get involved, please visit our action center at www.capwiz.com/nnfa/issues/



--
Vitanet ®, LLC

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CLA and the Catabolic Cascade
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Date: June 22, 2005 09:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CLA and the Catabolic Cascade

CLA and the Catabolic Cascade

Next fall, when you or a friend goes to the doctor to get a flu shot, notice how a low-grade fever starts. Notice how rundown you or your friend begin to feel for a day or so after the shot. It is as if you are dealing with a small portion of the disease. In some respects you are, but, in reality, the icky, yucky feelings we associate with sickness come from our body’s own response to an invasion. When the immune system goes on the o f f e n s i ve, it puts out hormones called cytokines. T h o s e cytokines cause fever and pain.

Doctors call this process the catabolic cascade. It is our body that produces it. An extreme example might have been when Jim Henson, the wonderful creator of Kermit the Frog, got an extreme bacterial infection. He died within about 12 hours. Although the bacteria caused some severe reactions, it was his body’s intense catabolic response that may have been the direct cause of death.

Cytokines are involved in more than just stimulating the immune system, they are involved in how the body accumulates fat, in how veins accumulate deposits and in how our body during disease can sometimes cause dangerous, rapid weight loss. CLA changes how cytokines work, but how it does it is not certain.

Here’s an example of why this is important: When young animals get sick, their immune systems kick into action. Besides contracting a feve r, the animals’ growth slow s . Furthermore, weight and muscle mass can be lost, not just because of loss of appetite, but because of degradation of muscle tissue. For a poultry farmer, this can be significant. In organized farms, bacteria can abound and young chicks often face sickness. Because their immune systems are firing, the cytokines can stunt growth and, accordingly, stunt the farmer’s profits.

Dr. Mark Cook was working on this dilemma in 1990 and jogging at the campus of the Un i versity of Wi s c o n s i n - Madison. During one of his regular exercise Sessions, he began chatting with Dr. Pariza. As researchers do, they began talking about their work. They decided to collaborate, seeing if CLA had an effect on this problem.

In 1993, the scientists at the University of Wisconsin-- Madison injected rat pups with endotoxin, the substances bacteria produce to do their damage.40 This injection activated their immune systems. They also did the same thing in two studies using chicks. In all three studies, the weight-loss was about half what it was during the other studies.

In a study published in 1994, re s e a rchers also injected endot oxin into mice. To some, they gave CLA, to others they didn’t After three days, the scientists weighed the mice and discove re d that those who also re c e i ved CLA in their diets lost much less weight. Indeed, after three days they weighed as much as the c o n t rol gro u p, which re c e i ved no endotoxin at all. The CLA - f e d g roup also had a much better appetite than those that re c e i ve d no CLA with endotoxin. They also had a higher muscle mass.41 Let’s repeat that. CLA gives a higher muscle mass in rats. Stop and think about the implications. Other studies have shown, and, we will get to them, that CLA also cuts the amount of food converted to fat. In an era of increasing battles with the bulge, CLA seems to show great promise. (That weight gain seems to be involved somehow with the immune system and cytokines indicates that working with cytokines may be how CLA affects body fat accumulation.) Yes, CLA can help cut the effects of immune stimulation, but does it do that at the expense of making our immune systems less effective? Does CLA affect how the body battles disease? Not from any evidence in any study. The 1993 studies measured several immune functions, and, if anything, the immune system worked better.42

Again, these are animal studies, not necessarily involved with how humans work. However, these studies involve more than one kind of animal, making it, again, more likely to be useful in humans.

Let’s speculate for a minute. When CLA cuts the catabolic cascade, doesn’t it make sense that the body would feel better, if only because the appetite is better? When CLA cuts weight loss, couldn’t that have immense benefits for patients suffering from long-term illnesses—including those illnesses that affect the immune system—who grow weak from a loss of muscle tone and from a loss of weight?

For the animal industry, of course, this nutrient clearly means better production methods and healthier animals. For those same animals, it seems possible to speculate that CLA may actually work as a growth factor for their young.43 For humans, this nutrient could mean feeling better and feeling stronger while the body fights off disease.

At the beginning of this booklet, we learned that CLA may be one of the most important nutrients discovered in recent years. The support for that statement should be clear. CLA, if the human studies hold true, could cut your risk for cancer, could lower your risk of heart disease, could help you feel better when you are ill, and improve muscle tone while decreasing body fat.

This research has one other interesting side effect. Cook says that during much of the research, graduate students helping in the work would continually report that animals were eating less. Indeed, the animals ate up to 30 percent less while gaining weight or helping the immune system.

If all animals in the world were fed CLA, and it cut feed intake by 30 percent, this would have strong implications on world starvation and feed efficiency. Especially in a world w h e re meat consumption may be growing. Cutting the amount of animal feed necessary to produce the same number of animals is vital. This, too, is a possible result of CLA.44

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Fats for Life - the quality of the fat you eat is probably much more important than the...
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Date: June 12, 2005 02:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fats for Life - the quality of the fat you eat is probably much more important than the...

Fats for Life by Henry Wolfe Energy Times, August 6, 2003

For years, many experts argued that the only good fatty foods were the ones you didn't eat. That was a big, fat mistake. Overwhelming evidence now shows that certain fats are not only necessary for optimal health, but that the quality of the fat you eat is probably much more important than the quantity.

Threatening Trans Fats

"The biggest thing wrong with the fats Americans eat today is that they are eating too many trans fatty acids," says Fred Pescatore, MD, author of The Allergy and Asthma Cure (John Wiley). "About 42,000 foods contain trans fats. These fats are linked to a higher risk of heart disease, stroke and cancer."

Trans fatty acids are fats that form when food manufacturers add hydrogen to fat molecules, a process called hydrogenation that makes fats stay fresh longer without growing rancid. Trans fats also form when foods are fried.

Hydrogenation extends the shelf life of refined foods like cakes, donuts, and crackers. Unfortunately, it also creates fats that many experts believe can compromise your health. In a study of the health effects of trans fats, 26 people agreed to eat a diet that changed every five weeks, continually shifting the types of fats in their meals (American Heart Association's Scientific Sessions 2000). All of the diets in the study provided 30% of calories from fat. One fifth of the fat came from either soybean oil, semi-liquid margarine, tub margarine, shortening, stick margarine or butter.

"We were interested in assessing what would happen when we substituted one fat for another," notes researcher Alice H. Lichtenstein, DSc, professor of human nutrition at Tufts University, Boston.

The study showed that as people ate more trans fatty acids (in the more solid margarines) and fewer polyunsaturated fats (in the liquid oils), their triglycerides increased after each meal. Triglycerides are blood fats that boost heart disease risk.

For instance, when these folks ate stick margarine, which is high in trans fats, their triglycerides climbed an average 18% higher than when they ate semi-liquid squeeze bottle margarine, a type of margarine that is softer because it is less hydrogenated. Stick margarine raised heart disease risk by causing a drop in HDL, or "good" cholesterol. Although butter increased HDL, it also caused a significant increase in LDL, the "bad" cholesterol that raises heart disease risk.

Dietary Advice

"The best dietary advice we can give people is to minimize their intake of animal and hydrogenated fats in order to reach the American Heart Association's target of 10% or less of total calories from saturated fat and trans fatty acids," Dr. Lichtenstein says. "That would mean consumers choosing low-fat and non-fat dairy products and lean cuts of meat, and the food industry decreasing the amount of hydrogenated fats used in their products." According to a study at Johns Hopkins University (Amer Coll of Card, 52nd Scientific Session, 3/30/03, Chicago), people who eat saturated fat have more visceral fat, fat surrounding their internal organs. This fat around the waist is now seen as a risk factor for heart disease and other illnesses.

Another hidden problem in our fat consumption, according to Dr. Pescatore, hides within canola oil. Dr. Pescatore says that although many consumers believe canola oil is beneficial to health, the refined canola oil sold in the US has had its potential health benefits removed during processing.

"People still think canola oil is healthy and eat too much of it," he says. "The problem with canola is that it is highly processed and refined....Processors hydrogenate canola oil to keep it from getting rancid."

According to Fred Ottoboni, PhD, coauthor of The Modern Nutritional Diseases (Vincente Books), "Canola oil is lightly hydrogenated to take out the omega-3 fatty acids (the healthiest, but most unstable, fats) and then the food manufacturers filter the trans fats out. I don't worry about the trans fats in canola, but the problem is the huge ratio of omega-6 fatty acids to omega-3s."

To get more of the omega-3 fatty acids, which are lacking in most Americans' diets, Dr. Pescatore advocates using macadamia nut oil. "Macadamia nut oil is higher in monounsaturated fats than olive oil; it is the healthiest fat with an omega-3 to -6 ratio of one to one."

The Omega-3 Difference

Omega-3 and omega-6 fatty acids are basic forms of fat found in oils. Fish oil, hempseed and flax oil are high in what are called omega-3s. Certain plant-derived oils like corn and soy are richer in omega-6 fatty acids.

"Primitive humans ate a diet that contained a one-to-one ratio of omega-3s and omega-6s," says Dr. Pescatore. "Today we (Americans) eat 20 times more omega-6 than -3; that's why we suffer so much chronic disease and chronic inflammation. For instance, the Japanese eat a (much better) diet that contains a two-to-one ratio of omega-6 fatty acids to omega-3." "Not all omega-6s are bad," he adds, "we just eat too many of them."

Switching to healthier fat isn't hard. Eat more fish. When cooking, stick to oils like olive oil and macadamia oil. The quality of your oil and your health may improve in a big, fat way.



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Summer Sports Nutrition Guide
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Date: June 11, 2005 03:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Summer Sports Nutrition Guide

Summer Sports Nutrition Guide by Joyce Dewon Energy Times, June 18, 2004

If you're hooked on exercise you're probably just as hooked on using top-notch equipment when you work out. Those who are serious about staying in shape buy the best running shoes, carefully pick out the best bikes and tread on durable treadmills. But do you pay just as much attention to your nutrition?

Scientists who have studied exercise have found that what you eat before, during and after workouts is crucial to maintaining your health, getting into shape and staying fit. To achieve your best athletic performance without getting injured or sick depends on optimum nutrition. When you carefully plan what to feed your exercised body, it rewards you by feeling and looking better.

Short 'n Sweet

If you thought long exercise Sessions were the only ways to get decent exercise benefits, take notice: small doses of exercise during the week can go a long way. " The important thing, apparently, is just do it," says Howard D. Sesso, ScD, author of an American Heart Association study on exercise and heart disease. In his study, exercisers demonstrated that several short Sessions of exercise were as good for the body as a single long session (Circ 8/00; 102:975-80). " Short Sessions lasting 15 minutes long appear to be helpful,"Dr. Sesso explains. Even walking about three miles per week, which is a moderate level of exercise, lowers your risk of heart disease by 10%.

No Sweat?

Some people glorify in working up a sweat; others curse the dampness. But putting in extra effort in even short bursts of activity pays off: experts have found that intense exercise burns more calories than more relaxed Sessions, more effectively reduces your risk of cardiovascular disease and helps stabilize blood sugar levels. In addition, it stimulates production of human growth hormone, which offsets some of the effects of aging (Exp Biol Med 2004 Mar; 229(3):240-6).

But don't go crazy if you haven't worked out in a long time. The intensity of the workout should match your physical fitness. According to the American Heart Association, when people exercise at a comfortable pace, their heart rate and level of exertion stay within a safe range, but still high enough to benefit their health. Strenuous activities, for those who can handle them, produce the most physiological bang for the jog. But brisk walking within your own level of fitness still offers significant benefits.

Feeding Your Muscles

When you exercise, you work and develop your muscles, which are made primarily out of protein. Despite this fact, many exercise experts have advocated high-carb diets for athletes. But, as John Ivy, PhD, and Robert Portman, PhD, point out in their book The Performance Zone (Basic Health), "[While] there is no doubt that aerobic athletes require more carbohydrate than strength athletes...we are now discovering that the addition of protein to a carbohydrate supplement offers significant benefits to aerobic athletes."

That is why researchers believe that consuming plenty of protein along with carbohydrates offers the best fitness benefits. Protein helps fuel activity more efficiently and aids in recovery after a session at the gym, allowing your body to repair muscle damage and build up muscle fibers.

During exercise, you break down muscle tissue. It is during recovery, after your exercise session ends, that muscles are rebuilt. At the same time, other cellular processes take place that adapt the body to working out.

According to Ivy and Portman, timing your intake of nutrients after exercise is crucial: "The ability of the muscle machinery to regenerate itself decreases very rapidly after a workout, so that the nutrients consumed more than 45 minutes after exercise will have far less impact in helping the muscles regenerate than nutrients consumed earlier."

Stresses and Tears

Engaging in athletics can cause microscopic muscle tears. These tears can cause a range of problems that, when you exercise excessively, can cause pain and injury.

Inflammation is the body's response to cellular damage. The damaged area can swell as the body sends white blood cells and other cells to repair the injured area. Unfortunately, the swelling can further damage the muscle cells.

Since inflammation can take 24 hours or more to cause the collection of cells in the injured area, it can be a day or two before the resulting muscle soreness reaches its peak painfulness and then starts to subside.

Cortisol, a hormone produced when you exercise strenuously, which can result in muscle fiber damage. Cortisol boosts protein breakdown, so it can be used to fuel muscle movement. But the more protein breaks down, the more potential exists for muscle fiber injury. Free radicals are caustic molecules that are created when the mitochondria (small structures in cells) create energy; these marauders can also cause microscopic shredding of muscle strands. As you increase your use of energy during exercise, you simultaneously increase the production of free radicals. This collection of free radicals can outstrip the body's antioxidant defenses, leading to extensive muscle damage and dampening of the immune system.

All of these cellular events can make you sore. They are also the reasons that athletes who overdo it day after day are liable to come down with nagging colds and a variety of infections.

Muscle Fuel

Your muscles use different substances for fuel depending on what you ask them to do. Lift a heavy weight and muscles recruit two processes called the creatine phosphate system and glycolysis to generate a large amount of quick energy. These are known as anaerobic types of energy production.

But if you jog, swim, bike or perform any other aerobic activity, the cells use oxygen in what is called cellular respiration to supply energy to working muscles.

When you exercise aerobically for extended periods of time, the energy available is generally limited by how much oxygen your body is capable of taking in and supplying to the muscles, where it takes part in energy production. In athletic circles, this upper limit is known as your VO2max.

The carbohydrates your body burns for energy during aerobic activity are taken from blood sugar and carbohydrate reserves called glycogen. (The muscles store glycogen, as does the liver.) During a workout session, your glycogen supply is limited to what is stored with your muscles. But blood glucose can be boosted by carbohydrate drinks, energy gels or bars.

Most people who work out have enough glycogen and blood sugar to fuel moderate aerobic activity for about two hours. After that, the body turns mostly to fat and protein stores to fuel exercise.

Fat Into the Fire

In contrast to the body's quickly diminishing supply of glycogen and blood sugar, fat can last for hours and hours of exercise. According to Portman and Ivy, a 200-pound man with 15% body fat has, theoretically, enough fat energy to run from Washington DC down to Miami Beach-and still has enough energy left over to jump into the ocean.

But using fat for energy is complicated; fat is stored in fat tissue and not readily available to working muscles. Plus, to burn fat for energy, the body needs carbohydrate-it cannot burn fat all by itself. What's more, the conversion of fat into energy doesn't go as quickly as carb conversion.

Protein is also used for energy when carbs run low. But the more you use protein for energy, the more you risk soreness as muscle fibers break down.

Prepare to Energize

To maximize your energy during exercise and minimize soreness, Portman and Ivy recommend some simple nutritional steps:

  • • Drink 14 to 20 ounces of water or a sports drink with electrolytes about a half hour before you work out. Consuming fluid helps stave off dehydration longer, helps you sweat more (which cools your body) and moderates the rise in body temperature that takes place during exercise. Portman and Ivy favor sports drinks to help you retain fluid and maintain your mineral balance.
  • • Eat carbohydrates an hour before exercising, which boosts glycogen and increases blood sugar and insulin. Portman and Ivy add that, alternatively, you can also consume a protein/carbohydrate sports drink about half an hour before working out. The protein helps protect muscle protein from being broken down.
  • • Drink small amounts of fluid frequently as you exercise to replace water lost through sweating. While some experts recommend only drinking enough to quench your thirst, most researchers agree that a sports drink with electrolytes is best to ensure proper mineral balance in your body.
  • • Consume carbs and protein during exercise. Portman and Ivy note that soccer players who consume sports drinks that contain electrolytes, carbohydrates and a bit of protein can perform more effectively. Cyclists who go on bike rides of three hours or more enjoy more endurance when they eat energy bars or consume other sources of carb and protein. Portman and Ivy advocate drinks that contain carbs and protein in a 4:1 ratio.

    Limit Soreness

    Taking protein and carbs while working out can limit muscle damage and curtail soreness. Carbs apparently drop your cortisol levels, and thereby limit muscle injuries linked to this hormone. While the mechanism that helps protein limit muscle soreness is not completely understood, it is possible that taking in protein while working out keeps the body from shredding muscle tissue in search of fuel.

    Supplements that contain antioxidants such as natural vitamin E and vitamin C (Portman and Ivy think you should take these during exercise) may limit free radical damage to muscle fibers.

    Muscle Reconstruction Plan

    If you want to help your exercise plan make you stronger, you should focus your after-exercise sports nutrition plan on these steps:

  • • Help your muscles recover from damage during activity and stimulate the rebuilding process
  • • Replace glycogen (carbohydrates) the muscles have used up during your workout
  • • Reinforce your immune system
  • • Replace water and minerals lost in sweat Even after you stop exercising, your muscles are still breaking down, according to Ivy and Portman. The key to putting the brakes on this breakdown and initiating the rebuilding process is by consuming a combination of protein and carbohydrate within 45 minutes after your workout is completed.

    The protein part of the equation is vital: don't merely indulge in only carbs after exercising. A recent study found that while carbs could help muscles rebuild, adding protein can make a big difference in improving your fitness (J App Phys 2/04).

    This combination of nutrients stimulates the pancreas so that it releases insulin. The release of insulin is the key, initial step that sets off a cascade of physiological events that speeds muscle recovery. Although many people think of insulin as an undesirable hormone-if you never exercise, too much insulin may help drive your blood sugar down and cause other problems-for exercisers, this hormone plays a crucial function in benefiting from exercise.

    By eating carbohydrate and protein soon after working out and stimulating insulin, according to Ivy and Portman, you help your body boost its synthesis of protein by:

  • • Increasing the amount of amino acids (protein building blocks) that get into the muscles-this can increase by up to 50%
  • • Increasing the production of protein synthesizing enzymes by up to two-thirds
  • • Slowing the breakdown of muscle proteins

    Drinking for Exercise The most obvious nutrient you lose during intensive exercise is water in your perspiration. However, that perspiration also contains an array of minerals known as electrolytes. So, for optimal performance and health, experts recommend you replace both the water and its minerals.

    Merely drinking water-instead of electrolyte-filled sports drinks-during prolonged aerobic activity can be dangerous. It leaves you vulnerable to a condition called hyponatremia, which can occur when your blood levels of sodium and other electrolytes drop, but your blood volume stays steady or increases because you drink lots of water.

    According to Edmund Burke, PhD, in his book Optimal Muscle Performance and Recovery (Avery), one out of four athletes who seek medical attention after a long race are suffering hyponatremia.

    " Typically," he says, "conscientious athletes get in trouble because they adhere too diligently to one recommendation: the need to drink lots of fluids. They tend to ignore another recommendation: The need to keep electrolytes up...for most endurance athletes the real problem is drinking too much water." Dr. Burke warns that you can possibly suffer hyponatremia even if you don't drink a lot of water.

    Signs of hyponatremia can be similar to those of heat exhaustion. But, while resting and cooling down can help alleviate heat exhaustion, that doesn't help hyponatremia. " To protect yourself against hyponatremia, start by paying attention to how much you sweat," Dr. Burke says. If your sweat seems very salty, burns your eyes or leaves an evident, white residue on your skin, you may be losing a great deal of sodium and should be diligent about eating salty foods. " You can also make sure you're getting enough sodium by drinking sports drinks instead of plain water during long (exercise) events," Dr. Burke notes.

    Exercise Matters

    Of course, no matter what you decide to eat or drink while exercising, the most important factor for your well-being is to get out to the gym, onto the track, or just on to the sidewalk, and do something, even if you only want to go out for a walk. No matter how old you are or what kind of shape you're in, you'll benefit from exercise.

    " It's solid evidence that across-the-board declines occur when people stop exercising," says Charles Emery, PhD, professor of psychology at Ohio State University (Health Psychology 3/04).

    Don't decline or remain supine. Let your fitness climb.



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    GABA to improve memory ...
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    Date: May 23, 2005 10:44 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GABA to improve memory ...

    Cerebral glutamate/GABA system to regulate learning and memory. Zhang, S. S.; Zhang, L.; Zhang, D. S. Pharmacol. Lab., Wenzhou Coll. Med., Wenzhou, Peop. Rep. China. Yaoxue Xuebao (1997), 32(8), 638-640. CODEN: YHHPAL ISSN: 0513-4870. Journal; General Review written in Chinese. CAN 131:111463 AN 1999:485466 CAPLUS

    Abstract

    A review with 28 refs., on pharmacol. of stimulation and injury of learning and memory, discussing the involvement of neurotransmitters GABA, glutamate, and piracetam, with the emphasis of glutamate/GABA system in regulation and maintenance of learning and memory.

  • over 24 medical studies stating GABA increases memory and learning.
  • Study done in laboratory on male rats state that Gaba increases memory and Learning

    GABA involvement in memory consolidation: evidence from posttrial amino-oxyacetic acid. Katz, R. J.; Liebler, L. Ment. Health Res. Inst., Univ. Michigan Med. Cent., Ann Arbor, MI, USA. Psychopharmacology (Berlin, Germany) (1978), 56(2), 191-3. CODEN: PSCHDL ISSN: 0033-3158. Journal written in English. CAN 88:164675 AN 1978:164675 CAPLUS

    Abstract

    In order to assess the possible effects of central GABA [56-12-2] activation on the consolidation of shock avoidance, the GABA inhibitor aminooxyacetic acid (I) [645-88-5] was administered posttrial to adult male rats. Learning was assessed over 9 widely spaced Sessions of 20 trials each. I-treated animals showed learning within Sessions and a lack of consolidation across Sessions. Controls, on the other hand, showed learning both within and across Sessions. This evidence agrees with previous reports suggesting GABA involvement in memory processes.

  • Gaba does improve memory


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