Search Term: " Stabilized "
Can reishi mushrooms help prevent cancer and other life-threateningdiseases?
May 03, 2019 03:59 PM
Reishi mushrooms and reishi extract have substantial health benefits, especially for boosting your immune system. Reishi mushrooms include a diverse array of bioactive compounds that, collectively, may boost cellular metabolism and restore the efficiency that the immune system tends to lose over time. Studies also indicate that reishi mushroom compounds may help induce immune cells to target cancer cells more aggressively, and boost the cancer-fighting functions of the spleen and thymus. Reishi mushrooms extracts may also help boost your overall immune system response against viruses and other pathogens.
"Reishi mushroom extracts can block the human immunodeficiency virus, hepatitis B virus, and other infectious microbes from compromising the health of the targeted organs."
Read more: https://www.naturalnews.com/2019-03-28-can-reishi-mushrooms-help-prevent-cancer-and-other-life-threatening-diseases.html
11 natural ways to lower your cortisol levels
August 22, 2018 09:53 AM
We've all heard about how cortisol levels can increase fat around the abdomen, but how do we lower these levels that are dangerous to our overall health? Reducing your stress levels is one of the main ways that you can decrease the presence of cortisol in your body. You can do this by finding ways to regulate your thinking into a more stabilized fashion such as learning how to participate in deep breathing and other meditative practices.
"It’s important for helping your body deal with stressful situations, as your brain triggers its release in response to many different kinds of stress."
Read more: https://www.healthnutnews.com/11-natural-ways-to-lower-your-cortisol-levels/
All about trace minerals.
March 18, 2014 10:26 AM
While much accentuation is put on the trace minerals that are discovered to be crucial to the human form, to be specific, calcium, iron, magnesium, phosphorous, and zinc, there are additionally follow minerals which help the figure to perform its normal schedules. Follow minerals are required by the constitution, yet just in little measurements. Moment measures of follow components can mean the distinction between poor and fitting health. A number of them perform distinctive, critical capacities which are needed by the constitution. In this article, we'll examine a portion of the diverse follow minerals that are of service to people.
Iodine is advantageous to the human figure because of the way that it serves to control advancement and usefulness in the thyroid organ. This is a capacity of most extreme criticalness, as the thyroid organ is answerable for to such an extent. The generation of vitality inside the human figure, fortified digestion system, discourse capability, and solid hair, skin, and teeth are all because of a legitimately working thyroid organ.
Copper is an alternate essential follow mineral. It has been discovered to be vital for legitimate assimilation of iron in the human form. It additionally works with the cell reinforcement Vitamin C to help structure elastin, which is a substance utilized within the muscles of the constitution. Fitting bone development, and also the best possible building of red platelets are likewise made conceivable because of copper.
Manganese, in itself, is capable cell reinforcement. Notwithstanding performing the capacities of a cancer prevention agent, manganese is answerable for fitting breakdown of amino acids and vitality generation. Vitamin B-1 and Vitamin E are likewise influenced by manganese, as it helps the form to metabolize them legitimately. Also, sex hormone creation is controlled by manganese.
While of service for all people, diabetics specifically profit from the best possible measurements of chromium. It helps insulin in the constitution to metabolize sugar, keeping glucose at a sensible level. Chromium is additionally answerable for serving to clean garbage out of our conduits, lessening cholesterol and triglycerides.
Potassium works in pair with sodium in regulation of the physique's waste procedures. It animates the kidneys to help free the assemblage of harmful waste. Heart rhythms might additionally be Stabilized by getting the correct dose of potassium. It is likewise known to encourage send more oxygen to the mind, which can bring about clearer considering.
Selenium is an alternate follow mineral that has critical cancer prevention agent properties. Some therapeutic reviews have demonstrated that a fitting selenium admission may bring about a diminished shot of contracting bosom, lung, colon and prostate malignancy.
The trace minerals recorded above are simply a portion of the more applicable follow minerals. There are numerous distinctive follow minerals that your constitution requirements and it might take truly a long rundown to depict every one of them. To get all the minerals you need, make sure to consume your everyday necessities of products of the soil. This sustenance’s hold probably the most vitamin and mineral-rich mixes accessible, and are beneficial to consume, to boot!
NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE
December 10, 2009 04:23 PM
NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE™
NADH is the biologically-active form of vitamin B-3 (niacin), and is involved in a wide range of functions throughout the body. An easier way to understand it, is to think of NADH as a biological spark plug that makes it possible for us to become and remain energetic, active, and functioning at our best. Remove the “spark” and some of the most basic human functions will inevitably suffer. This is not speculation. It is the result of decades of scientific investigation that has examined the link between nutrition and chronic conditions; notably those related to cellular life cycles and apoptosis, excessive fatigue, enzyme decline, free radical expansion, cognitive disparity, intracellular balance, normalized aging, and many more important aspects of human health.*
Based on a wealth of ongoing studies, we have a great understanding of the benefits of NADH. Not only is it an effective source of cellular energy, it is also one the body’s versatile electron donors—the molecule most frequently degraded during oxidation. Because of these characteristics NADH is, however, also very unstable with regard to light and oxygen, which leads to a very rapid loss of overall effectiveness. Additionally, poor lifestyle choices, such as the use of tobacco, excessive consumption of alcohol, drugs, and prescription medications, sleep deprivation, genetically-engineered foods, and a host of others can all inhibit the activity of NADH within the body. Hope is not lost, however.
NOW® NADH contains a patented form of NADH from Panmol® - the first natural Stabilized, stomach acidresistant form of this unique vitamin B3 supplement. Panmol® uses a patented process to naturally preserve its effectiveness. The end result is a highly stable, and bioavailable NADH which can easily withstand the harsh, acidic environment of the stomach and digestive tract; a breakthrough in the battle against many of todays’ most chronic conditions. NOW® NADH is available in both 10 and 20 mg potencies. Both varieties have been further enhanced with 200 mg of Bioenergy RIBOSE™ to support its cellular energy support properties.*
Who Stands to Benefit from NADH
With a proper supply of amino acids and/or B3 vitamins (niacin) the human body is, in fact, capable of producing a limited reserve of NADH. Under chronic strain however, the body’s need for NADH increases. As we age, the body’s ability to manufacture NADH becomes increasingly limited. With this in mind, the following groups stand to benefit the most from incorporating NOW® NADH into their supplement regimen.
• Those who work in stressful, cognitively-demanding professions
October 23, 2009 11:10 AM
Since the beginning of civilization, flax has been around. The early Swiss used the fibers for weaving, while Egyptians decorated their tombs with carvings of the flax plant and wrapped mummies in linen due to the high esteem they had for this plant. The fibers of the flax plant were a main source of clothing in biblical times, with even Christ being believed to have been buried in linen. The use of flaxseed oil was recommended by Hippocrates for inflammations of the mucous membranes. Charlemagne required his subjects to eat the seeds to remain healthy during the early eighth century in France.
Flaxseed has many medicinal properties, as the oil has been used as a remedy for colds, coughs, sore throats, mucus, congestion, lung conditions, and as an expectorant. The herb is soothing to the mucous membranes and has been used to treat asthmatic conditions.
Additionally, this herb is a mild, natural laxative, providing roughage to aid the body when constipation is a problem. It is also healing on the stomach and intestines. Flaxseed oil can be very beneficial for gastritis, ulcers, and heartburn, while the tea can be used to help detoxify the liver and purify the blood. This herb is also believed to aid in reducing the clotting tendency of blood, potentially lowering the risk of heart attacks and reducing cholesterol levels in blood. It is also used for reducing inflammation and for urinary tract irritations. Crushed flaxseed, made into a poultice, is often used to treat sprains or bruises.
Unrefined, cold-pressed flax oil is considered to be the richest vegetable source of omega-3 and 6 oils, which are essential fatty acids. These oils are useful for balancing the hormones in the body and helping in the weight-loss process. Essential fatty acids help to improve the function of the glands, which in turn helps weight loss. Those individuals on low or no-fat diets often experience symptoms of fatigue and no weight loss which is partly due to the absence of essential fatty acids in the diet. A small amount of essential fatty acids actually helps one to lose weight. This herb also contains lignans, which are a type of fiber that has anti-estrogenic activity. A study done at the National Cancer Institute followed vegetarian women. The study indicated a correlation between a high amount of lignans in the blood and a lower risk for breast cancer. It has also been discovered that people living in countries where flaxseed is consumed in high amounts have a lower risk for developing both breast and colon cancer. It should be noted that Stabilized flaxseed has a higher content of lignans than any other food.
Flaxseed can also be helpful in preventing heart disease and lowering cholesterol. One study found that ground flaxseed, when added to the diet, can reduce the incidence of heart disease.
The seeds of the flaxseed plant are used to provide anti-neoplastic, demulcent, emollient, expectorant, mucilant, mild purgative, and vulnerary properties. Primarily, flaxseed is extremely beneficial in dealing with arthritis, cardiovascular health, high cholesterol, constipation, immune disorders, multiple sclerosis, and skin disorders.
Additionally, this herb is very helpful in treating bronchitis, cancer, colds, gallstones, weak heart, jaundice, liver, lung disorders, muscular rheumatism, and tumors. For more information on the many beneficial effects provided by flaxseed, please contact a representative from your local health food store.
August 23, 2008 11:59 AM
Acidophilus is correctly named Lactobacillus acidophilus, and is one species of Lacobacillus used commercially in the preparation of certain types of yoghurt. The name refers to the fact it is found in milk (lacto), is rod-like in shape like many bacteria (bacillus) and it likes acidic conditions (acidophilus). It not only likes them, but creates them.
In fact, acidophilus thrives at a pH of 4-5 or less, and occurs naturally in the gastrointestinal tract of humans and animals, and also the mouth and vagina. It ferments milk to lactic acid, and dies in the presence of sunlight, excessive moisture and at high temperatures. Some, but not all, strains are probiotic, or ‘friendly’ bacteria that aid digestion and help to protect against harmful bacteria and their toxic emissions.
The fermentation of nutrients by friendly bacteria produce acids, such as the lactic acid previously referred to, hydrogen peroxide and other substances hostile to harmful organisms, and also reduces the population of harmful bacteria by competing for their food. There are additional health benefits that shall be discussed later, but first some comments about the stability of acidophilus to heat.
The growth rate of acidophilus reaches an optimum at around 36-37F (2.2C), and it tends to die off at temperatures much above this over a period of time. It also tends to be sensitive to oxygen and moisture, and if exposed to heat, moisture and oxygen, a supplement will lose its potency over time. This is true of all such supplements, and after purchase must be quickly refrigerated. It is possible, however, to purchase Stabilized forms of acidophilus that die off slower than normal. This extra resistance is built in during the manufacturing process, and many forms of acidophilus claim to be stable. Although there will never be a truly stable form of the probiotic, these Stabilized versions do last longer than those not claimed to be so.
During manufacture, the bacteria are first concentrated by removing the excess liquid by means of sedimentation, ultra-filtration, reverse osmosis and centrifuging. A substance is then added to protect the bacteria from the shock of freezing and the acidophilus freeze dried. A stabilizer is then added to maintain its properties between freezing and consumption.
It has also been found that bacteria grown at higher pH levels last longer than those at lower pH. The packaging is also important, and since the bacteria are sensitive to oxygen, nitrogen flushing the bottles will improve the stability of the product. Glass bottles are less porous than plastic, and so is the preferred packaging material for maximum stability and life. Another factor is refrigeration. If you keep the bottle in the fridge it was last a lot longer than at room temperature, but take care not to freeze it since acidophilus does not freeze well. If it is not refrigerated then it will quickly lose its potency.
The form in which you take the supplement is immaterial regarding the potency: at least initially. However, through time the powder will become less potent quicker, because it will adsorb oxygen and moisture. Otherwise the form in which it used is immaterial. So, yes, acidophilus can be Stabilized, but only for a while, and if allowed to warm up to room temperature in the presence of oxygen will quickly degrade, although this takes more than just a day or two.
Many health benefits are claimed for Lactobacillus acidophilus, although your daily consumption to achieve these should be at least 2 billion CFU, and preferably 5 billion. You can also fortify the bacteria with a prebiotic of fructooligosaccharides (FOS). These provide nutrition for the acidophilus and accelerate its growth.
One thing to be careful of is assuming that yoghurt contains acidophilus. It does not contain sufficient to be of benefit to you. Commercial yoghurt acidifies over time and kills off the bacteria, so commercial yoghurt sitting on a supermarket shelf has very little beneficial bacterial content. Natural yoghurt is better, and certainly contains beneficial bacteria, but not enough to make a significant difference. A supplement is therefore needed if you are to keep your intestinal tract sufficiently healthy. If you cannot take dairy products, acidophilus is available in non-dairy form. The major health benefits they impart are:
1. Digestive Problems.
Acidophilus can control many types of digestive disorder, particularly traveler’s diarrhea. In fact if you are traveling to countries where drinking water might be a problem, also take some acidophilus and this will tend to prevent you from becoming ill. Even if you drink bottled water, there are still washed salads, beverages made with local water and showers and the like whereby you could ingest some dodgy water.
Acidophilus, especially when supported by FOS, helps both to hydrate the feces, and improve their transport through the colon, an also to improve the general health and well-being of your entire intestinal system.
3. Yeast Infections (Candidiasis)
Acidophilus possess antifungal properties that kill off yeasts, particularly Candida albicans found in the vagina. This is due to the lactic acid produced by the bacteria, and there is evidence that gastrointestinal yeasts are affected in the same way by the oral probiotic. Furthermore, when bacteria and yeasts are killed off by medication, including friendly bacteria, the sites they occupied on the intestinal walls become free and acidophilus should be present to take these up and prevent any more yeast or bacterial infections. That is one reason why probiotics should be taken immediately after a course of antibiotic treatment.
4. Immune System Support
Lactobacillus acidophilus is believed to modify the balance of microbes in the intestine so as to lead to an enhanced production of antibodies, and white blood cells with increased phagocytic activity. The bacteria also appear to have some reducing properties, which can also give support to the immune system through the resultant antioxidant properties.
However, by far the most important property of probiotics are their properties in acidifying the intestinal tract, and so rendering them less attractive to harmful pathogens, and in producing hydrogen peroxide which has a similar effect. They also produce natural antibiotics, and there is now doubt that a supplement of acidophilus will provide you with several health benefits and also make you feel fitter and more alert.
August 19, 2008 08:38 PM
Folic acid is an important vitamin to the developing fetus in that it aids cell development, particularly those cells involved in the development of the baby's spine. A deficiency can result in neural tube defects, in which the neural tube, down through which the central nervous system passes, fails to close properly.
However, let's first discuss the substance itself so that its function in that process can be more easily understood. Neither should we ignore the other benefits that folic acid gives us, or the problems we can have in the event of a deficiency.
Folic acid is a form of Vitamin B9, sometimes referred to as Vitamin M. Its anionic form is known as folate, which is the form in which it is frequently offered in supplements. Incidentally, it gets its name from the Latin for leaf, so is from the same root as foliage. It is water soluble, and like Vitamin C can be leached through the body if not immediately used.
It is available naturally from leafy and green vegetables such as lettuce, broccoli, spinach and peas, but is also available in fortified breakfast cereals, sunflower seeds and some fruits. You would not normally suffer a deficiency, but if you are taking anticonvulsants, have liver problems or undergoing kidney dialysis, then you might need a supplement. Pregnancy, of course, is the important case in which a supplement should be taken, although, surprisingly, many mothers-to-be are unaware of this.
New body cells need folate for their production, particularly when they are dividing and growing rapidly such as during pregnancy and in infancy. The formation of DNA depends on many chemical entities, among them four nitrogenous bases, of which three, thymine and the two purine bases, adenine and guanine, depend on folate for their synthesis. If the growing fetus is lacking folate then DNA synthesis will be hindered. This retards cell division and growth.
Among the conditions this can cause are a form of anemia known as megaloblastic anemia, and neural tube deficiencies, where the sheath that surrounds the main nerve canal up the spine fails to close properly. The best known of such neural tube defects is spina bifida, though any condition caused by a lack of cell division can also occur. Anemia can be contracted by both adults and children, since production of red blood cells takes place constantly throughout your lifetime. These are the reasons why folic acid or folate is used in breakfast cereals.
The biochemistry is fairly simple to understand, and is important because it explains the importance of two other B vitamins, B3 and B12, in DNA synthesis. The initial stages are a six step reaction that forms methyl tetrahydrofolate from folate, starting with the reduction of folate to dihydrofolate, and then a further reduction to the tetrahydrofolate (THF). Vitamin B3 (in the form of nicotinamide adenine dinucleotide phosphate) is an essential cofactor for these reductions. Vitamin B12 is necessary as an acceptor for the methyl-THF so that it can continue along the biochemical pathway - now that is too complex to discuss here!
However, the inference you can rightly draw from this is that a deficiency of Vitamin B12 can cause what is known as a 'methyl trap', whereby the methy-THF cannot be used, and so a deficiency in Vitamin B12 can lead to the same symptoms as a folic acid or folate deficiency.
The implications of that are that vitamin B12 is also an essential component of a pregnant woman's diet. The problem here is that this vitamin is available only from animal sources, including dairy products. Its presence in vegetable organisms such as certain algae and fungi has been proposed, but it is believed that the cobalamin (chemical term for the vitamin) from these sources is not bioavailable to humans.
Vegans, therefore, who do not eat dairy products, will need a Vitamin B12 supplement in addition to folic acid or folate, particularly when they are pregnant and with young growing children. In this respect, a vegan diet is unsuitable for young children until their rapid growth period has Stabilized.
For those of you wondering why the biochemistry above was discussed: that is your answer. Such discussions can frequently explain why certain supplements are necessary, or certain diets should be reconsidered under particular circumstances. Such things are easier to understand and accept when the logic behind them are explained. A folic acid supplement taken from the onset of pregnancy up to 12 weeks at least, and also a Vitamin B12 supplement in the case of those with a low meat intake, should prevent neural tube defects such as spina bifida.
A daily supplement of 0.4 mg should be sufficient, along with a diet rich in green vegetables, fortified cereals and breads and oranges. Your greens are best steamed since prolonged boiling destroys folic acid - as it destroys Vitamin C. One source of folic acid that you might read about is liver, and its additional iron content might lead you to believe this to be a good component of your diet when pregnant. However, although normally a very nutritious food, liver should be avoided during pregnancy due to its high Vitamin A content. This can be harmful to your baby.
Finally, there are some circumstances under which the dose during pregnancy should be greater. If you have previously had a child with a neural tube defect, or have an NTD yourself (or your partner), if you are diabetic, if you have celiac disease (a gluten allergy) or are taking anti-epileptic medication, you should increase your dose to 5 mg (milligrams) for which you will likely need a prescription from your physician.
NTD is rare, so don't over-worry much about it, but take the above precautions to put your mind at rest since pregnancy is not a time during which you should be nervous but to enjoy. That will pass on to your growing baby, which will then itself be happy.
August 14, 2008 09:35 AM
Antioxidants are the body’s main defense against free radicals as they work against the substances that create oxidants and the reactive substances that result from oxidation and reduction. Antioxidants neutralize free radicals by supplying the missing electron so that the molecule may be Stabilized. There are many different types of antioxidants ranging from dietary antioxidants to those that the body produces itself. The four major antioxidant nutrients are vitamin A (beta carotene), vitamin C, vitamin E, and selenium.
Vitamin A, the first vitamin to ever be isolated, is essential for the proper function of the eyes and maintenance of the skin. It is found in the retina of all mammals as well as the liver. Vitamin A works to increase our resistance to infections by keeping all the linings in the body healthy. It is necessary for the health and moisture of the skin and the specialized cells lining the eyes, nose, mouth, throat, lungs, esophagus, stomach intestines, and urinary tract. When these cells don’t have sufficient vitamin A, they thicken and harden, which is extremely detrimental to health and makes us more susceptible to infection. Vitamin A also protects the body from cardiovascular disease and cancer, and is necessary for new cell growth, something that is extremely important in slowing the aging process.
Beta carotene is the best known of the two carotenoids that form vitamin A, being composed of two vitamin A molecules that are split apart by liver enzymes when the body is low in vitamin A. If body levels are sufficient, the enzymes remain inactive and beta carotene does not divide, making it a safe source of vitamin A, without producing the toxic effects that come with high levels of vitamin A itself. If excess beta carotene is consumed it is stored in fat tissue or circulated in the blood. Beta carotene is one of the most powerful antioxidant nutrients as it can prevent free radical formation and inactivate existing free radicals. Once free radicals have been formed, it traps them and breaks the chain reaction that occurs.
Vitamin C holds a crucial role in many body processes that are necessary for life, among these being its role in collagen formation. Collagen is important in the every structure of the body, as it works like glue to bind cells together to form tissues. The integrity of collagen depends on vitamin C. Vitamin C also functions as one of the most powerful free radicals to prevent the damage that contributes to aging and age-related diseases.
It also works against pollution and toxins that damage cells and cause mutations, possibly even reducing some food carcinogens and protecting lung lining fluids against damage by air pollution. Vitamin C is important in the immune system and it also increases immunity to infectious diseases, lowers total cholesterol, enhances the effect of vitamin E, promotes wound healing, growth, tissue repair, and helps with the utilization of iron.
Vitamin E prevents aging by prolonging the useful life of cells found in the body. It also works to protect vitamin C and vitamin A from free radical activity so that they may remain potent. Vitamin E has the ability to stop a free radical chain reaction as it is happening and plays an extremely important role in preventing the per-oxidation of lipids (cholesterol). It protects the cell membrane, which in turn causes it to help protect the body from disease.
Selenium, one of the ten essential trace minerals, can be found in all tissues of the body. It is best known for its antioxidant role and its function in fighting cancer. It protects the liver from damage and works to stop lipid per-oxidation. Selenium is vital in maintaining the elasticity of body tissues and preventing the oxidation of fatty tissue, in turn combating the effects of aging. Selenium causes the skin to be healthier, muscle mass and tone are more easily maintained, and the heart is strengthened. Selenium works along with vitamin E, enhancing the effects of each other. It is important to get our vitamins and minerals on a daily basis to maintain a health happier life.
Ubiquinol Reduced CoQ10
April 07, 2008 01:05 PM
Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.
Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.
In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.
CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.
While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.
In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.
A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.
As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.
The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a Stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.
Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.
Oxy Boost – Oxygenate your Life!
July 06, 2006 02:43 PM
Oxygen is the basis of all life and is found in the air we breathe and the water we drink. Increasing oxygen levels can have very positive effects, including improved mental clarity, endurance, immunity, better digestion and increased energy.
Oxygen is the key to a healthy immune system as well as every metabolic function in our bodies. Trillion of cells use oxygen to create energy every second of every day of our lives. Atmospheric pollution and deforestation play an important role in terms of the quality of air we breathe.
Oxy boost is all natural. It contains distilled water, sodium chloride (from sea salt), bioavailable oxygen, and essential and trace minerals. Oxy boost is the world’s premier Stabilized oxygen supplement, containing one of the highest concentrations of activated oxygen available today. It is pH balanced (approximately 7.4—a perfect pH for internal and external use). This is why Oxy Boost is so unique in the field of oxygen supplements.
Oxy boost has been proven in independent laboratory studies to be completely non-toxic in any concentration and at any amount. Oxy boost is safe to use both orally (sublingually or in water) and topically. Oxy boost does not depend on the digestive process to be absorbed.
The body’s first line of defense
A lack of sufficient oxygen in the blood stream reduces the body’s first line of defense. This has been clearly established in medical literature. Oxy boost safely increases the available oxygen levels in the bloodstream.
Works with other nutrients
Oxy boost can be taken with other nutritional supplements in fact; it may be safe to assume that oxy boost can even increase the efficacy of such supplements. Oxy boost works hand in hand with all other nutrients including amino acids, minerals and vitamins. These all require oxygen to be assimilated by the body and for utilization in the metabolic processes. The higher the oxygen saturation level in the blood and tissues, the more efficient and effective are the metabolic processes involving these nutrients.
We recommend that Oxy boost be taken on an empty stomach, preferably 30 min before eating or two hours after eating, to get the greatest physiological benefits from the product. Oxy boost is available in regular and therapeutic (2.5 times the concentration of regular Oxy boost) strengths.
Pomeratrol™ Fact Sheet
December 19, 2005 09:09 AM
Pomeratrol™ Fact SheetNeil E. Levin, CCN, DANLA 9/28/04
USER: Those needing antioxidant protection; People with a family history of cell growth abnormalities; Anyone concerned with aging
KEY INGREDIENT(S): Pomegranate fruit standardized extract 200 mg. (Punica granatum) containing 80% total polyphenols, including 40% Ellagic acid, Resveratrol (100% trans-resveratrol) 20 mg. from a blend of Japanese knotweed root extract (Polygonum cuspidatum) and grape skin extract (Vitis vinifera)
POTENTIAL BENEFITS: Ellagic acid is a polyphenol compound found in raspberries, strawberries, pomegranates, and other fruit. It has been shown to normalize cell death of abnormal cells, a process called apoptosis. This enhances the body’s cell growth control system by providing an important plant substance. It may bind to DNA to prevent damage to this all-important genetic material. This is a key step in preventing cell damage that leads to signs of aging.
The American Cancer Society says that research in animal and laboratory models has found that ellagic acid inhibits the abnormal growth of certain cells. Research at Ohio State University indicates that berries typically contain a few milligrams per ounce of ellagic acid, the actual level varying quite a bit from variables such as species, variety and growing conditions.
Resveratrol is an antioxidant compound that is a phytoestrogen, or plant estrogen, which is protective of hormone-mediated cells in the body. Resveratrol is a potent antioxidant if Stabilized. If not stable, it may quickly metabolize out of the body. This compound is believed responsible for some of the beneficial effects of moderate red wine drinking on the cardiovascular system. Resveratrol is also considered to be beneficial to smokers’ lung tissue if it is Stabilized to last long enough in the system to be transported there. Resveratrol is also an inhibitor of the COX-2 inflammatory enzyme and encourages cell death (apoptosis) of abnormally growing cells. In insect experiments resveratrol even repaired DNA, leading to a longer life for healthy cells even as it helped get rid of unhealthy cells. Again, this ability to protect cells and help the body rid itself of abnormal cells is a key factor in preventing signs of aging. One liter of red wine contains between 1.5 and 3 mg. of resveratrol.
OTHER IMPORTANT ISSUES: Resveratrol is a difficult substance to stabilize. Because of the difference between resveratrol produced in the oxygen-poor environment in red wine and the form of resveratrol in unStabilized supplements, it has long been thought that resveratrol supplements were not very effective in comparison with wine. Knowing the importance of how a resveratrol supplement is metabolized, Now’s scientific staff has recently developed a special technique of stabilizing this compound in order to have an antioxidant effect closer to drinking a good glass of wine. While both trans and cis forms of resveratrol are naturally occurring, most of the recorded health benefits are attributed to the trans form. Now’s Pomeratrol provides trans-resveratrol.
DOSE: One capsule per day. Resveratrol has been used safely in studies at doses equivalent to 500 mg./day.
COMPLEMENTARY PRODUCTS: Other antioxidants and plant compounds: Vitamin C, pycnogenol, grape seed extract, and alpha lipoic acid.
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. There are some indications that resveratrol is a mild anticoagulant ("blood thinner"), and it also may help keep blood vessels to remain open and flexible. Caution should be used by those on blood-thinning drugs. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
December 17, 2005 09:42 AM
Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood
As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body.
There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable.
Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel.
SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.*
SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance.
As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants.
Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health.
SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification.
SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were granted to allow the production of SAMe in a Stabilized form.
SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a Stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability.
This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed
Allibiotic CF Fact Sheet
December 07, 2005 01:37 PM
Allibiotic CF Fact SheetNeil E. Levin, CCN, DANLA 03/09/05
LIKELY USERS: People seeking support of the immune system and intestinal flora
KEY INGREDIENTS: Allicin (“AlliSure” patented, Stabilized allicin from fresh garlic); Olive Leaf Extract (Olea Europaea with 18% minimum Oleuropein content); Elderberry extract, from fruit/berry, 60:1 concentrate (equivalent to 2,500 mg. of fresh berries of Sambucus nigra); Oil of Oregano (wild oregano from Origanum vulgare) ImmunEnhancer AG (trademarked Arabinogalactan from Larch Tree, Larix occidentalis)
MAIN PRODUCT FEATURES: AlliSure is the clinically tested, patented and stable form of allicin. Not allicin potential, but actual allicin. Allicin represents the immune supporting nutrients of raw garlic, and is chemically similar to penicillin, though with different physical properties. AlliSure shares garlic’s abilities to help maintain healthy cholesterol and blood pressure levels, and also has been shown to raise levels of a key T cell to enhance immune system function. Like raw garlic, AlliSure has antimicrobial properties linked to its ability to react with sulfur-containing metabolic enzymes. Allicin is also shown in studies to play a role in controlling blood sugar and abnormal cell growth.
Black Elderberries have strong antioxidant properties, containing flavonoids like anthocyanidins. They have been studied in relation to inhibition of viral replication and of minor inflammations.
Olive Leaf has been used as an antioxidant, cholesterol and blood viscosity regulator, and vasodilator. But its most important use has been as a way to help the body deal with undesirable organisms in the vital respiratory and intestinal areas.
Oil of Oregano (wild oregano, wild marjoram) contains carvacrol and thymol, which are responsible for much of its antimicrobial activities. It also has some anti-inflammatory effects.
Arabinogalactan from Larch tree bark (ImmunEnhancer AG) can help speed the immune system’s response to undesirable organisms and is often compared to Echinacea. It has also been shown to promote the growth of beneficial intestinal bacteria.
ADDITIONAL PRODUCT INFORMATION: Patented and trademarked ingredients enhance quality controls and have clinical research. Rosemary Oil provides antioxidant protection for the capsule contents. Enteric coating protects the capsule from stomach acid to deliver its contents past the stomach. This helps to assure full potency and reduces the possibility of the oils repeating.
SERVING SIZE & HOW TO TAKE IT: One softgel twice daily, preferably with meals. Try one before using the full dose.
COMPLEMENTARY PRODUCTS: Probiotics, Antioxidants, D-Flame
CAUTIONS: Pregnant & lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. Discontinue use if any uncomfortable side effects occur. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey. Adv Ther. 2001 Jul-Aug;18(4):189-93. (AlliSure was used in this study.)
Abramovitz D, Gavri S, Harats D, Levkovitz H, Mirelman D, Miron T, Eilat-Adar S, Rabinkov A, Wilchek M, Eldar M, Vered Z. Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet. Coron Artery Dis. 1999 Oct;10(7):515-9. PMID: 10562920
Ankri S, Miron T, Rabinkov A, Wilchek M, Mirelman D. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997 Oct;41(10):2286-8. PMID: 9333064
Cellini L, Di Campli E, Masulli M, Di Bartolomeo S, Allocati N. Inhibition of Helicobacter pylori by garlic extract (Allium sativum). FEMS Immunol Med Microbiol. 1996 Apr;13(4):273-7. PMID: 8739190
Chowdhury AK, Ahsan M, Islam SN, Ahmed ZU. Efficacy of aqueous extract of garlic & allicin in experimental shigellosis in rabbits. Indian J Med Res. 1991 Jan;93:33-6.
Eilat S, Oestraicher Y, Rabinkov A, Ohad D, Mirelman D, Battler A, Eldar M, Vered Z. Alteration of lipid profile in hyperlipidemic rabbits by allicin, an active constituent of garlic. Coron Artery Dis. 1995 Dec;6(12):985-90. PMID: 8723021
Elkayam A, Mirelman D, Peleg E, Wilchek M, Miron T, Rabinkov A, Oron-Herman M, Rosenthal T. The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats. Am J Hypertens. 2003 Dec;16(12):1053-6. PMID: 14643581
Feldberg RS, Chang SC, Kotik AN, Nadler M, Neuwirth Z, Sundstrom DC, Thompson NH. In vitro mechanism of inhibition of bacterial cell growth by allicin. Antimicrob Agents Chemother. 1988 Dec;32(12):1763-8.
Focke M, Feld A, Lichtenthaler K. Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase. FEBS Lett. 1990 Feb 12;261(1):106-8.
Hirsch K, Danilenko M, Giat J, Miron T, Rabinkov A, Wilchek M, Mirelman D, Levy J, Sharoni Y. Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation. Nutr Cancer. 2000;38(2):245-54. PMID: 11525603
Patya M, Zahalka MA, Vanichkin A, Rabinkov A, Miron T, Mirelman D, Wilchek M, Lander HM, Novogrodsky A. Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras. Int Immunol. 2004 Feb;16(2):275-81. PMID: 14734613
Rabinkov A, Miron T, Mirelman D, Wilchek M, Glozman S, Yavin E, Weiner L. S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):144-153. PMID: 11118647
Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998 Feb 2;1379(2):233-44. PMID: 9528659
Sela U, Ganor S, Hecht I, Brill A, Miron T, Rabinkov A, Wilchek M, Mirelman D, Lider O, Hershkoviz R. Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression. Immunology. 2004 Apr;111(4):391-9. PMID: 15056375
Shadkchan Y, Shemesh E, Mirelman D, Miron T, Rabinkov A, Wilchek M, Osherov N. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. J Antimicrob Chemother. 2004 May;53(5):832-6. Epub 2004 Mar 24. PMID: 15044429
Tsai Y, Cole LL, Davis LE, Lockwood SJ, Simmons V, Wild GC. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Planta Med. 1985 Oct;(5):460-1. PMID: 3001801
Uchida Y, Takahashi T, Sato N. [The characteristics of the antibacterial activity of garlic (author's transl)] Jpn J Antibiot. 1975 Aug;28(4):638-42. PMID: 1099271
Yasuo Yamada and Keizô Azuma. Evaluation of the In Vitro Antifungal Activity of Allicin. Antimicrob Agents Chemother. 1977 April; 11(4): 743–749.
Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 423.
Gruenwald J, Brendler T, Jaenicke C, et al. (eds). PDR for Herbal Medicines. Montvale, NJ: Medical Economics, 1998, 1116–7.
Mascolo N, Autore G, Capasso G, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987;1:28–31.
Murkovic M, Abuja PM, Bergmann AR, et al. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. Feb2004;58(2):244-9.
Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press, 1996, 104–5.
Yesilada E. Inhibitory Effects of Turkish Folk Remedies on Inflammatory Cytokines: Interleukin-1Alpha, Interleukin-1Beta and Tumor Necrosis Factor Alpha. J Ethnopharmacol. Sept1997;58(1):59-73. Youdim KA, Martin A, Joseph JA. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radical Biol Med 2000;29:51–60.
Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Alt Compl Med 1995;1:361–9.
OLIVE LEAF EXTRACT:
American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.
Bennani-Kabchi N, et al. Effects of Olea europea var. oleaster leaves in hypercholesterolemic insulin-resistant sand rats. Therapie. Nov1999;54(6):717-23.
Bisignano G, et al. On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. J Pharm Pharmacol. Aug1999;51(8):971-4. Gonzalez M, et al. Hypoglycemic activity of olive leaf. Planta Medica. 1992;58:513-515. Visoli F, et al. Oleuropein protects low density lipoprotein from oxidation. Life Sciences. 1994;55:1965-71. PDR for Herbal Medicines, 2nd edition. Montvale, NJ: Medical Economics Company; 2000:557.
Petroni A, et al. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.Thromb Res. Apr1995;78(2):151-60. Pieroni A, et al. In vitro anti-complementary activity of flavonoids from olive (Olea europaea L.) leaves. Pharmazie. Oct1996;51(10):765-8. Zarzuelo A, et al. Vasodilator effect of olive leaf. Planta Med. Oct1991;57(5):417-9. OREGANO OIL (OIL OF OREGANO, WILD OREGANO, WILD MARJORAM):
Dorman HJ, et al. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. Feb2000;88(2):308-16. Force M, et al. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. May2000;14(3):213-4.
Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 1999;86:985–90.
Kelm MA, Nair MG, Strasburg GM. Antioxidant and Cyclooxygenase Inhibitory Phenolic Compounds from Ocimum sanctum Linn. Phytomedicine. Mar2000;7(1):7-13. Lamaison JL, et al. Medicinal Lamiaceae with antioxidant properties, a potential source of rosmarinic acid. Pharm Acta Helv. 1991;66(7):185-8.
Ponce MM, Navarro AI, Martinez GMN, et al. In vitro effect against Giardia of 14 plant extracts. Rev Invest Clin 1994;46:343–7 [in Spanish].
Stiles JC, Sparks W, Ronzio RA. The inhibition of Candida albicans by oregano. J Applied Nutr 1995;47:96–102.
Tantaoui EA, Beraoud L. Inhibition of growth and aflatoxin production in Aspergillus parasiticus by essential oils of selected plant materials. J Environ Pathol Toxicol Oncol 1994;13:67–72. ImmunEnhancer AG (Larch tree Arabinogalactan)
Corado J, et al. Impairment of Natural Killer (NK) Cytotoxic Activity in Hepatitis C Virus (HCV) Infection. Exp Immunol. 1997;109:451-457. Currier NL, Lejtenyi D, Miller SC. Effect over time of in-vivo administration of the polysaccharide arabinogalactan on immune and hemopoietic cell lineages in murine spleen and bone marrow. Phytomedicine. 2003 Mar;10(2-3):145-53. PMID: 12725568
Egert D, et al. Studies on Antigen Specificity of Immunoreactive Arabinogalactan Proteins Extracted from Baptisia tinctoria and Echinacea purpurea. Planta Med. 1992;58:163-165. Gonda R, et al. Arabinogalactan Core Structure and Immunological Activities of Ukonan C, An Acidic Polysaccharide from the Rhizome of Curcuma longa. Biol Pharm Bull. 1993;16:235-238. Hagmar B, et al. Arabinogalactan Blockade of Experimental Metastases to Liver by Murine Hepatoma. Invasion Metastasis. 1991;11:348-355. Kelly GS. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern Med Rev. 1999 Apr;4(2):96-103. Review. PMID: 10231609
Kim LS, Waters RF, Burkholder PM. Immunological activity of larch arabinogalactan and Echinacea: a preliminary, randomized, double-blind, placebo-controlled trial. Altern Med Rev. 2002 Apr;7(2):138-49. PMID: 11991793
Levine PH, et al. Dysfunction of Natural Killer Activity in a Family With Chronic Fatigue Syndrome. Clin Immunol Immunopathol. 1998;88:96-104. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr. 2001 Aug;20(4):279-85. PMID: 11506055
Rolfe RD. The Role of Probiotic Cultures in the Control of Gastrointestinal Health. J Nutr. Feb2000;130(2S Suppl):396S-402S.
Salyers AA, Vercellotti JR, West SE, Wilkins TD. Fermentation of mucin and plant polysaccharides by strains of Bacteroides from the human colon. Appl Environ Microbiol. 1977 Feb;33(2):319-22. PMID: 848954
Uchida A. Therapy of Chronic Fatigue Syndrome. Nippon Rinsho. 1992;50:2679-2683.
ENADA® NADH 5mg - NEW PRODUCT ANNOUNCEMENT
August 03, 2005 05:23 PM
NEW PRODUCT ANNOUNCEMENTENADA® NADH 5mg
Energy-Rich Coenzyme—Convenient 60-tab Size!
1 tablet contains:
Suggested Use: 1 tablet daily in the morning, on an empty stomach, with water. Wait 30 minutes before eating. Or, take as recommended by your health care professional.
Lowering cholesterol safely
July 27, 2005 04:10 PM
Lowering cholesterol safely.
By Kim Vanderlinden, N.D., D.T.C.M.
Atherosclerosis and its complications are major causes of death in the United States and have reached epidemic proportions throughout all of the Western world. Heart disease accounts for 36% of all deaths among Americans and ranks as the number-one killer; stroke; another complication of atherosclerosis; is the third most common cause of death.
Foremost in the prevention and treatment of heart disease is the reduction of blood cholesterol levels. The evidence overwhelmingly demonstrates that elevated cholesterol levels greatly increase the risk of death due to heart disease. The first step in reducing risk for heart disease is keeping your total blood cholesterol level below 200 mg/dl (milligrams per deciliter).
Not all cholesterol is bad; it serves many functions in the body, including the manufacture of sex hormones and bile acids. Without cholesterol, many body processed would not function properly.
Cholesterol is transported in the blood by molecules known as lipoproteins. Cholesterol bound to low density lipoprotein, or LDL, is often referred to as the “bad” cholesterol, while cholesterol bound to high-density lipoprotein, or HDL, is referred to as the “good” cholesterol. LDL cholesterol increases the risk of heart disease, strokes, and high blood pressure, while HDL cholesterol actually protects against heart disease.
LDL transports cholesterol to the tissues. HDL, on the other hand, transports cholesterol to the liver for metabolism and excretion from the body. Therefore, the HDL-to-LDL ratio largely determines whether cholesterol is being deposited into tissues or broken down and excreted. The risk for heart disease can be reduced dramatically by lowering LDL cholesterol while simultaneously raising HDL cholesterol levels. Research has shown that for every one percent increase in HDL levels, the risk for a heart attack drops three to four percent.
Dietary cholesterol is a major risk factor in developing atherosclerosis. The evidence is substantial. However, several studies have shown that a lower dietary cholesterol intake was associated with up to a 37% lower risk of death from any cause, or an increased life expectancy of roughly 3.4 years.
Although dietary cholesterol intake is an important contributor to atherosclerosis, most of the cholesterol in the body is actually manufactured in the liver. Reducing dietary cholesterol alone is not always sufficient to lower blood cholesterol levels.
In an attempt to reduce blood cholesterol levels, many physicians are ignoring the need to give dietary recommendations and are instead utilizing drugs as the primary treatment. Using drugs before diet is clearly not the best approach, in terms of both effectiveness and cost. In fact, the Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Cholesterol in Adults clearly states: “Dietary therapy is the primary cholesterol-lowering treatment.”
The drugs lovastatin (Mevacor), prevastin (Pravachol), and simvastatin (Zocor) are commonly used to lower blood cholesterol levels. The main side effect of these drugs is liver damage. In fact, due to the seriousness of the possible adverse effects on the liver, it is necessary to have periodic blood tests to determine if the drug is harming the liver. Other side effects include: muscle breakdown, muscle pain, nausea, diarrhea, flatus, abdominal pain, headache, and skin rash.
The most important first approach to lowering a high cholesterol level is to follow a healthful diet and lifestyle. The dietary changes are simple: Eat less saturated fat and cholesterol by reducing or eliminating the amounts of animal products in the diet; increase consumption of fiber-rich plant foods (fruits, grains, and legumes); and lose weight, if necessary. Lifestyle changes include; Regular aerobic exercise; stop smoking; and reduce or eliminate consumption of coffee (both caffeinated and decaffeinated).
Here are the six key recommendations of U.S. Surgeon General, American Heart Association, and the National Research Council’s Committee on Diet and Health:
When there is a need for additional support to the dietary and lifestyle practices that can lower cholesterol levels, it simply makes more sense to use safer and more effective natural alternatives. When evaluating overall effectiveness, both LDL and HDL cholesterol levels must be taken into consideration. When you look at the cost, safety, and effectiveness, it is clear that natural alternatives are substantially superior to standard drug therapy.
Keep in mind that the natural alternatives discussed are, just like the dugs, still best utilized in a comprehensive program that stresses a healthful diet and lifestyle.
Niacin, or vitamin B3, has long been used to lower cholesterol levels. In fact, niacin is recommended by the National CholesterolEducation Program as the first “drug” to use to lower blood cholesterol levels.
The safest form of niacin at present is known as inositol hexaniacinate. This form of niacin has long been used in Europe to lower cholesterol levels and also to improve blood flow. It yields slightly better results than standard niacin, but is much better tolerated, both in terms of flushing and, more importantm long term side effects.
Gugulipid is the standardized extract of the mukul myrrh tree that is native to India. Several clinical studies have confirmed that gugulipid has an ability to lower both cholesterol and triglyceride levels. Typically, cholesterol levels will drop 14% to 27% in a four- to twelve-week period, while triglyceride levels will drop from 22% to 30%.
The dosage of gugulipid is based on its guggulsterone content. Clinical studies have demonstrated that gugulipid extracts standardized to contain 25 mg of guggulsterone per tablet given three times per day is an effective treatment for elevated cholesterol levels, elevated triglyceride levels, or both.
Garlic and onions exert numerous beneficial effects on the cardiovascular system, including lowering blood lipids and blood pressure. Numerous studies have demonstrated that both garlic and onions are effective in lowering LDL-cholesterol and triglycerides while simultaneously raising HDL-cholesterol levels.
Without question, the best approach to lowering cholesterol levels is through diet and lifestyle modifications. When additional support is require, there are safer and more effective natural alternatives to commonly prescribed drugs.
The goal of therapy, whether natural or synthetic, is to get blood lipid levels down into target ranges as quickly as possible. Once the target range has been achieved, begin reducing the amount of medicine by half, or take it every other day. Recheck your cholesterol levels in one month. If they have Stabilized or continued to improve, you may no longer need the medication. If the levels begin to rise again, return to previous dosage.
If you are currently on a cholesterol-lowering drug, you must consult your doctor before discontinuing the medication.
PYCNOGENOL - ITS REMARKABLE BENEFITS
July 13, 2005 12:26 PM
PYCNOGENOL - ITS REMARKABLE BENEFITS
New to North America but not to Europe, this natural product is considered safe and effective in the treatment of various diseases and for the maintenance of optimal health. This family of bioflavonoids is non-toxic, water soluble and highly bioavailable. Because proanthocyanidins scavenge free radicals so effectively, they have shown remarkable curative effects. Extensive research demonst rates that proanthocyanidins are such potent antioxidants, they find and neutralize free radicals with great rapidity, allowing cells to regenerate rather than deteriorate. Specific actions associated with Pycnogenol include:
PYCNOGENOL SPECIFICALLY TARGETS: SKIN AND ELASTICITY
Testing has suggested that Pycnogenol flavonoids exhibited an anti-enzyme effect which prevented the break down of collagen and elastin, the very compounds which keep skin firm and inhibit the formation of wrinkles.7
TUMOR RELATED DISEASES
Unquestionably, studies have shown that Pycnogenol has the ability to inhibit cellular mutations.8 The implications of this finding for anyone suffering from tumor related disease which originates from cellular malfunctions should not be underestimated.
The potential of Pycnogenol to pr e vent cellular deterioration or uncontrolled growth is profound to say the least. Several investigations have shown that if it is taken on a daily basis, Pycnogenol benefits people suffering from cardiovascular diseases and breast tumors.9 In addition, double blind placebo controlled studies have indicated that patients suffering from circulatory insufficiencies and diseases of the lymph system showed significant improvement in pain control and vessel elasticity after taking these flavonoids.10
Subsequent experiments concluded that the family of bioflavonoids contained in Pycnogenol is capable of improving night vision and initialing “a rapid and marked improvement of visual performances after glare in comparison with control group.”11
WATER RETENTION AND EDEMA
Pycnogenol is particularly valuable for anyone who suffers from water retention and edema. Studies at the Institute of Physiology at the Bulgarian Academy of Sciences confirm that this biofl avonoid compound Stabilized capillary walls, which decreased fluid leakage into tissues which causes swelling and pressure.12
WHAT PATHOLOGICAL CONDITIONS RESPOND TO PYCNOGENOL?
The bioflavonoids found in Pycnogenol have been clinically indicated in the following pathological conditions:
PYCNOGENOL HAS THERAPEUTIC VALUE FOR THE FOLLOWING CONDITIONS:
PYCNOGENOL CAN CROSS THE BLOOD-BRAIN BARRIER
One of the most significant advantages of this flavonoid compound is its ability to cross the blood-brain barrier. Consequently, it acts as an invaluable therapeutic agent in treating depression, chronic fatigue, insomnia or loss of memory.
ANTI-ULCER FORMING PROPERTIES
Other scientific tests have indicated that proanthocyanidins also posses anti-ulcer properties and may work to prevent the formation of undesirable chemicals in the stomach.13
Battle Fatigue! Don't passively accept chronic exhaustion and weakness.
June 10, 2005 10:06 PM
Battle Fatigue! Don't passively accept chronic exhaustion and weakness. by Joanne Gallo Energy Times, December 6, 1999
Most folks wouldn't seek the distressing distinction of suffering chronic fatigue syndrome. Aside from a dizzying array of discomforts associated with the malady, the lack of a definitive cause, and few remedies offered by the medical establishment, scornful skeptics lob accusations of laziness or boredom or just plain moodiness. "Snap out of it!" they say, with little sympathy or understanding. "Just get moving!"
But if you're one of more than 3 million Americans affected by chronic fatigue, you know your problem is not all in your head. Your symptoms are real and they extend far beyond mere tiredness. In addition to a debilitating sense of fatigue that can make everyday existence feel like an overwhelming struggle, you may suffer from impaired concentration and memory, recurrent sore throats, nagging headaches, muscle and joint pain, swollen lymph nodes and fitful sleep. The persistence of any one of these effects alone could be debilitating, but the overall diminished capabilities of the chronic fatigue sufferer can become the most discouraging aspect of the disease.
But before you give up hope on kicking this energy-sucking ailment, look to natural ways to boost your immune system and regain your stamina for a more healthy and productive life. New research points to powerful, energy enhancing supplements which, combined with a nutritious diet and stress reducing techniques, can help you reclaim your body from a swamp of sluggishness.
Part of the public's misconceptions about chronic fatigue syndrome (CFS) may stem from vague definitions of exactly what it is and its causes.
In the '80s, CFS was often mentioned in the same breath as the Epstein-Barr virus, which garnered much notoriety as the "yuppie flu": a state of chronic exhaustion that often plagued young, overworked professionals, as the media trumpeted. CFS was initially thought to be the result of the Epstein-Barr virus, and the two were often considered to be the same thing. Since the Epstein-Barr virus causes mononucleosis, the term "chronic mono" was also thrown around to refer to long-lasting states of fatigue.
Today, CFS is defined as a separate disorder from the Epstein-Barr syndrome. Researchers have found that CFS is not caused exclusively by the Epstein-Barr virus or any other single infectious disease agent. According to the Centers for Disease Control (CDC) in Atlanta, CFS may have multiple causes, in which viruses or other infectious agents might have a contributory role. Some of these additional possible culprits include herpes simplex viruses, candida albicans (yeast organisms), or parasites.
According to the CDC, a person can be definitively diagnosed with CFS when she or he experiences severe chronic fatigue for six months or longer that is not caused by other medical conditions, and must have four or more of the following problems recurrently for six consecutive months: tender lymph nodes, muscle pain, multi-joint pain without swelling or redness, substantial impairment in short-term memory or concentration; sore throat, headaches, unrefreshing sleep and postexertional malaise lasting more than 24 hours.
Even if you are not diagnosed with CFS, you could still probably use some help in fending off fatigue. You may suffer from another poorly understood condition like fibromyalgia, which causes similar symptoms of exhaustion and pain with additional stomach discomfort. You may cope with another ailment like hypoglycemia or low thyroid function that zaps your energy. Or you could be like almost every stressed-out American adult trying to do it all at the expense of your well-being. Though researchers still search for a definitive cause for CFS, one thing is certain: Constant stress and poor nutritional habits weaken the immune system's ability to ward off a host of debilitating viruses and organisms. So before you run yourself down and succumb to a chronic condition, learn how you can build up your defenses now.
Some of the most exciting new research in CFS treatments focuses on NADH or Coenzyme 1, an energy-enhancing nutritional supplement. This naturally-occurring substance is present in all living cells including food, although cooking destroys most of it. Coenzymes help enzymes convert food and water into energy and NADH helps provide cellular fuel for energy production. It also plays a key role in cell regulation and DNA repair, acts as a potent antioxidant, and can reportedly improve mental focus and concentration by stimulating cellular production of the neurotransmitters dopamine, noradrenaline and serotonin.
A recent study conducted at Georgetown University Medical Center in Washington, DC, and reported in the February 1999 issue of The Annals of Allergy, Asthma & Immunology, showed that chronic fatigue sufferers improved their condition significantly by taking Enada, the Stabilized, absorbable, oral form of NADH. The researchers found that 31% of those who took the supplement achieved significant improvement in relief of their symptoms, and a follow up study showed that 72% achieved positive results over a longer period of time.
Coenzyme-A and Coenzyme Q-10 (Co-Q10) are related coenzymes also necessary for energy production.
According to Erika Schwartz, M.D., and Carol Colman, authors of Natural Energy: From Tired to Terrific in 10 Days (G.P. Putnam's Sons) CoQ10 in combination with the nutrient carnitine enhances cellular energy production, thereby boosting energy levels. Coenzyme-A is required to initiate the chemical reactions that involve the utilization of CoQ10 and NADH for the production of energy at the cellular level.
Another important energy-enhancing nutrient is D-ribose, a simple sugar that is crucial to many processes in your body. D-ribose stimulates the body's production of adenosine triphosphate, or ATP, an energy-rich chemical compound that provides the fuel for all body functions. D-ribose is essential to the manufacture of ATP and maintaining high levels of energy in the heart and skeletal muscles.
In addition to these new nutrients, a host of more familiar vitamins and minerals can help banish fatigue. According to Susan M. Lark, M.D., author of the Chronic Fatigue Self Help Book (Celestial Arts) nutritional supplements help stimulate your immune system, glands and digestive tract, promote proper circulation of blood and oxygen, and provide a calming effect. Some of Lark's recommended nutrients for building and regaining strength include:
Vitamin A: Helps protect the body against invasion by viruses that could trigger CFS, as well as bacteria, fungi and allergies. Supports the production and maintenance of healthy skin and mucous membranes, the body's first line of defense against invaders. Also supports the immune system by boosting T-cell activity and contributing to the health of the thymus, the immune-regulating gland.
Vitamin B Complex: Depression and fatigue can result from the body's depletion of B vitamins, which can occur from stress or drinking too many caffeinated beverages. Studies have provided preliminary evidence that CFS patients have reduced functional B vitamin status (J R Soc Med 92 , Apr. 1999: 183-5). The 11 factors of B complex are crucial to glucose metabolism, stabilization of brain chemistry and inactivation of estrogen, which regulate the body's levels of energy and vitality. n Vitamin C: Helps prevent fatigue linked to infections by stimulating the production of interferon, a chemical that can limit the spread of viruses. Helps fight bacterial and fungal infections by maintaining healthy antibody production and white blood cells. Also necessary for production of adrenal gland hormones which help prevent exhaustion in those under stress.
Bioflavonoids: Help guard against fatigue caused by allergic reactions; their anti-inflammatory properties prevent the production of histamine and leukotrienes that promote inflammation. Bioflavonoids like quercetin are powerfully antiviral.
Vitamin E: Has a significant immune stimulation effect and, at high levels, can enhance immune antibody response.
Zinc: Immune stimulant; improves muscle strength and endurance. Constituent of many enzymes involved in metabolism and digestion. n Magnesium and Malic Acid: Important for the production of ATP, the body's energy source. Magnesium is also important for women who may develop a deficiency from chronic yeast infections.
Potassium: Enhances energy and vitality; deficiency leads to fatigue and muscle weakness.
Calcium: Combats stress, nervous tension and anxiety.
Iodine: Necessary to prevent fatigue caused by low thyroid function, as it is crucial for the production of the thyroid hormone thyroxin.
In addition to nutrients to bolster your immunity, herbal remedies can also help suppress viral and candida infections. Garlic is a powerful, natural antibiotic, while echinacea and goldenseal have strong anti-infective abilities. Other botanicals help combat tiredness and depression: stimulating herbs such as ginger, ginkgo biloba, licorice root and Siberian ginseng can improve vitality and energy. For anxiety, moodiness and insomnia try passionflower or valerian root, which both have a calming effect on the central nervous system.
Eating For Energy
Supplements can only do their best if you eat a nutritious diet. Start by cutting out large quantities of sugar, caffeine, alcohol, dairy products, red meat and fat.
But what are the best foods when trying to restore energy or recover from illness? "High nutrient content foods with a good balance of proteins and carbohydrates," answers Jennifer Brett, ND, interim clinic director and chair of botanical medicine at the University of Bridgeport College of Naturopathic Medicine.
"You want foods with high nutritional value-that's where vegetables end up looking better than fruit."
Brett enthusiastically pushes that "universal food," as she calls it: chicken soup.
"In China," she says, laughing, "they do make chicken soup, and they do think of it as healing, because they add astragalus and shiitake mushrooms. Vegetable soups with chicken or fish have high nutritional value and are easy to digest."
The same principle applies to juices, Brett says. Juices are a good way to tastefully get more phytonutrients from fruits and vegetables into your diet. Toss in protein powder, and you can make a complete meal in your blender.
"You get more energy from juicing," she explains, "more accessible nutrients and carbohydrates that are not bound up in fiber." Brett's additional recommendation: oatmeal.
"It's got protein and carbohydrates combined with a lot of minerals, which you may not get from a sugary cereal," she says. "Sure, they spray some vitamins on them, but if you don't drink the milk in the bottom of the bowl, you'll miss out on them. You might as well take a multivitamin."
Look to fiber for superior energy enhancement. Natural Energy author Schwartz calls it downright "miraculous": "In terms of conserving precious energy, fiber-rich foods are your cells' best friends," she writes. "It takes smaller quantities of them to give you a full, satisfied feeling. They release all their benefits slowly, which allows the cells to extract nutrients with much less effort. Then these fiber-rich foods graciously leave the body with ease and efficiency." Among these "slow burn" foods that Schwartz says raise blood sugar slowly and steadily and maintain energy evenly:
Alfalfa sprouts-high in fiber and low in cholesterol.
Apples-one medium unpeeled provides 10% of the recommended daily fiber dose; unlike sweeter fruits, which are rich in healthful fiber, they help regulate blood sugar.
Broccoli-along with such greens as cauliflower, cabbage, kale, collard greens and broccoli rabe, it's packed with fiber, vitamins and minerals n Brown rice, wild rice, other whole grains-fiber treasure troves, including barley, quinoa, millet and buckwheat.
Corn-excellent fiber source.
Lentils and other legumes-high in fiber, delicious beans are rich in culinary possibilities.
Oat bran and wheat bran-mix into yogurt or add to cereal for the best available access to fiber.
Popcorn-an excellent snack.
Citrus for More Energy
If constant colds and infections are draining your energy, healthy helpings of citrus fruit may be the pickup you need. According to Robert Heinerman, in Heinerman's Encyclopedia of Healing Juices (Parker), citrus fruit have been used for more than a thousand years as natural remedies for a wide variety of ailments:
Kumquat juice is supposed to help clear up bronchitis. Lemon juice with a pinch of table salt eases a sore throat. Lime juice in warm water soothes aches and cramps from the flu. Tangerine juice can break up mucous congestion in the lungs. Along with citrus' vitamin C, these fruits also supply carotenoids, antioxidants that provide disease-preventing benefits. Citrus also often contain calcium, potassium, folate (a B vitamin that fights against heart disease), iron and fiber.
Fruits are loaded with phytochemicals, naturally occurring chemicals that give fruit their vibrant colors. Yellow, red and orange fruits are also high in flavonoids, like quercetin, a substance which fights cancer. Quercetin also aids in prevention of cataracts and macular degeneration, according to author Stephanie Beling, MD, in her book Power Foods (Harper Collins).
Even the US Department of Agriculture agrees on this flavonoid's benefits, noting in its phytochemical database that quercetin is an "antitumor promoter, antiasthmatic, anticarcinogenic, antiplaque, cancer-preventive, capillariprotective." (Quercetin is also available as a supplement.)
Don't Avoid Avocados
For a vitamin rich food, few items beat the avocado which holds vitamins E and C as well as some B vitamins (B6, niacin, riboflavin). A significant source of beta carotene, though not nearly as much as carrots or sweet potatoes, avocados also contain high amounts of the minerals potassium, magnesium, copper and zinc.
Just 15 grams of avocado delivers about 81 international units of vitamin A as beta carotene. Beta carotene, a carotenoid in fruits and vegetables, is converted to vitamin A in the body. This vitamin, aside from providing antioxidant protection from damaging free radicals, is necessary for good eyesight, healthy skin and healing.
In addition, the avocado, like all of these healthy foods, tastes great. Which means that you can pep up and not have to sacrifice taste for zest.
Healthy Mind, Healthy Body
Remember that the path to wellness begins in your mind. Stress-reducing activities like yoga, meditation and massage and aromatherapy can have a great rejuvenating effect on your body. If you can learn to handle stress effectively instead of letting it control you-and strengthen your system with the right nutrients and diet-you'll find that fatigue can be a sporadic visitor rather than a chronic companion.
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May 31, 2005 05:05 PM
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May 18, 2005 06:17 PM