Search Term: " Weak "

	NSAIDs vs. Curcumin: Which One Relieves Joint Pain Without Stopping Healing?	Darrell Miller	9/14/26
	The Ultimate Guide to Cellular Longevity: NAD+, Methylation, and Senolytics	Darrell Miller	9/10/26
	Can Akkermansia Muciniphila help the body fight leaky gut?	Darrell Miller	11/5/25
	The Role of Vitamin B12 in Energy Production	Darrell Miller	5/29/24
	The Importance of Collagen for Your Health: Why You Should Care	Darrell Miller	11/6/23
	Benefits of Vitamin D-3 In The Body!	Darrell Miller	8/5/23
	The Importance of Vitamin B-12	Darrell Miller	11/5/22
	Collagen: What is it and why should you care?	Darrell Miller	10/29/22
	All You Need to Know About L-Carnitine	Darrell Miller	10/28/22
	The Many Health Benefits of Copper Glycinate	Darrell Miller	10/25/22
	The Many Benefits of Graviola(Diabetes, Liver, Parasites)	Darrell Miller	10/11/22
	Collagen for Healthy Joints, Bones and Skin	Darrell Miller	10/3/22
	The Benefits of NOW Calcium & Magnesium Citrate Powder with Vitamin D3	Darrell Miller	9/21/22
	The Consequences of Not Getting Enough Sleep	Darrell Miller	9/14/22
	Stress, the body, and a possible solution.	Darrell Miller	9/9/22
	Vitamins C and D: The Immune System Supplements You Need	Darrell Miller	8/2/22
	Delta-8 THC Shows Promise in Combating Myocarditis	Darrell Miller	4/29/22
	No to Pain Pills and Yes to Safe and Effective Curcumin	Darrell Miller	9/4/20
	Zinc supplementation can benefit individuals with erectiledysfunction, reveals study	Darrell Miller	5/14/19
	4 reasons you should eat more mushrooms	Darrell Miller	5/9/19
	Cocoa isn’t just delicious – dies show it fights fatigue, too?	Darrell Miller	4/30/19
	Understanding the many benefits of cannabis in cancer treatment	Darrell Miller	4/24/19
	Cancer patients found to benefit from cannabis; scientific studyanalyzed outcomes of 2,970 cancer patients to confirm results	Darrell Miller	4/24/19
	Eat These Vitamin C-Rich Foods To Boost Your Immunity - NDTV	Darrell Miller	4/4/19
	8 Health Hazards Caused by Lack of Vitamin D	Darrell Miller	2/27/19
	Curcumin Possesses ability to repair brain damage caused bystrokes	Darrell Miller	2/15/19
	HIV-1 people can boost their immune system with Korean red ginseng	Darrell Miller	2/11/19
	6 foods that are high in B vitamins - Sportskeeda	Darrell Miller	2/8/19
	Supplement with magnesium if you have diabetes it helps reduceinflammation in your body	Darrell Miller	1/30/19
	Long-term consumption of yerba mate found to strengthen yourdigestive system	Darrell Miller	1/4/19
	Study: PQQ (pyrroloquinoline quinone) may prevent and even reverseAlzheimer's	Darrell Miller	1/4/19
	Help ward off infections and improve your immune system withoregano oil	VitaNet, LLC Staff	11/13/18
	Natural remedies for osteoporosis: Several medicinal plants havebeen found to improve bone health without the side effects of medication	VitaNet, LLC Staff	10/21/18
	Signs and symptoms of zinc deficiency - do you know what to lookfor?	Darrell Miller	9/22/18
	Anthocyanin Benefits the Brain, Eyes & Immune System	Darrell Miller	6/1/18
	Try These 5 Tricks To Speed Up Your Metabolism Naturally	Darrell Miller	5/29/18
	Smoking marijuana found to have the same weakening effect on the blood vessels as cigarettes	Darrell Miller	4/24/18
	A flavonoid found in guava and Osage orange has antioxidant properties that can reduce inflammation and improve “neurological deficits”	Darrell Miller	1/23/18
	I Used These 4 Tricks To Cure Candida In A Week	Darrell Miller	1/19/18
	If You Often Have Headaches, Low Energy, and Insomnia, Start Consuming These	Darrell Miller	1/15/18
	How to beat stage 4 cancer: For one man, going vegan and quitting chemo saved his life	Darrell Miller	1/7/18
	Is your Iron deficiency causing low energy?	Darrell Miller	9/1/17
	Scientists: Children need microbes, not antibiotics, to develop immunity	Darrell Miller	8/22/17
	Foundations in Health	Darrell Miller	8/4/17
	Brain cancer symptoms: Do YOU know the signs of John McCain's RARE aggressive type?	Darrell Miller	7/23/17
	Help, and hope: Could cannabis possibly help fight cancer?	Darrell Miller	7/21/17
	Miracle In A Glass: This Juice Fights Almost All Allergies!	Darrell Miller	6/26/17
	4 symptoms you should never ignore	Darrell Miller	6/6/17
	With This Natural Syrup Look What Happen to your body - How to Treat Anemia	Darrell Miller	6/4/17
	AMAZING. This Happens To Your Body WHEN YOU DRINK ALKALINE WATER!!	Darrell Miller	5/31/17
	Kudzu Root: Beneficial Herb or Just a Hyped Plant Invader?	Darrell Miller	5/27/17
	Never Ignore These Warning SIGNS OF VITAMIN B12 DEFICIENCY!	Darrell Miller	4/25/17
	Magnesium 'could prevent broken bones'	Darrell Miller	4/19/17
	Is pine tree bark the key to healthier, stronger teeth?	Darrell Miller	4/13/17
	Eating These Foods Can Help You Get Your Daily Dose of Vitamin D - Pulmonary Fibrosis News	Darrell Miller	4/8/17
	Selenium Benefits: A Unique Trace Mineral That Provides Powerful Cancer Prevention	Darrell Miller	4/5/17
	Eating anti-inflammatory foods may reduce symptoms of rheumatoid arthritis	Darrell Miller	3/22/17
	Adaptogens: Why you need these super herbs in your diet	Darrell Miller	3/18/17
	Watch ANOTHER Man with Severe Parkinson’s Take Cannabis Oil to Settle his Tremors	Darrell Miller	3/16/17
	Vitamin D plays essential role in health	Darrell Miller	3/11/17
	Make your bones stronger by following this diet	Darrell Miller	3/8/17
	Home Remedies For Dry Cough That Will Give You Relief	Darrell Miller	2/27/17
	IF YOU ARE LOSING YOUR HAIR AND YOU HAVE BRITTLE NAILS, This Is What You Need!!	Darrell Miller	2/20/17
	All you need to know about fatty liver	Darrell Miller	2/17/17
	Does depression boost the risk of cancer death?	Darrell Miller	2/8/17
	Menopause: anti-inflammatory diet could help prevent fractures and boost bone health	Darrell Miller	2/3/17
	Signs You Have a Vitamin Deficiency	Darrell Miller	1/13/17
	4 signs that you have unhealthy bones	Darrell Miller	1/1/17
	Tired? Weak? You're not 'just getting old'; something is wrong	Darrell Miller	12/27/16
	The Sky's Not Falling! Media Misreporting DEA on CBD “Illegality”	Darrell Miller	12/23/16
	5 Sure Fire Ways to Know if You Have Hashimoto’s	Darrell Miller	12/22/16
	How inflammation interferes with the formation of new bone material	Darrell Miller	12/14/16
	Nourish your bones with vitamins - The Detroit News	Darrell Miller	12/13/16
	4 Ways Food Can Fight Muscle Soreness	Darrell Miller	12/10/16
	How to strengthen your bones	Darrell Miller	12/10/16
	Is Glutathione The Fountain Of Youth?	Darrell Miller	12/6/16
	Hormone therapy could help improve bone health in menopausal women	Darrell Miller	12/4/16
	Give your skeleton some love	Darrell Miller	11/25/16
	Diabetes and bone loss: Strategies to manage bone health with diabetes	Darrell Miller	11/23/16
	Science says you can worry yourself sick	Darrell Miller	11/17/16

Date: September 14, 2026 11:22 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: NSAIDs vs. Curcumin: Which One Relieves Joint Pain Without Stopping Healing?

Comparative Analysis of NSAIDs versus Curcumin in Musculoskeletal Tissue Repair

Primary Biological Mechanisms and Pharmacological Targets

The functional divergence between these two compounds becomes clear when considering an intuitive mechanical analogy. Tissue trauma resembles damage to a commercial building, where initial inflammation functions as the construction and demolition crew tasked with clearing rubble, stabilizing the foundation, and laying down fresh structural framing. NSAIDs function like abruptly cutting electrical power to the entire work site: the noisy machinery stops instantly and the immediate disturbance ceases, but the construction workers lose the power necessary to clean the debris and erect permanent walls. Conversely, curcumin operates as an experienced site manager: it silences unnecessary chaos and prevents site vandalism while ensuring that the skilled workers - specifically chondrocytes in cartilage and tenocytes in tendons - remain fully active, supplied, and capable of completing the restoration.   

At the cellular level, NSAIDs exert their effects through the catalytic inhibition of cyclooxygenase enzymes, categorized as constitutive cyclooxygenase-1 (COX-1) and inducible cyclooxygenase-2 (COX-2). Membrane phospholipids damaged during injury release arachidonic acid, which COX enzymes convert into pro-inflammatory lipid mediators known as prostanoids, most notably prostaglandin E2 (PGE2). Nonselective NSAIDs block both isoforms, while selective coxibs specifically target COX-2. By shutting off PGE2 production, NSAIDs rapidly elevate pain thresholds and blunt localized swelling. However, because PGE2 also functions as a vital signaling cue for cellular recruitment, angiogenesis, and cellular proliferation, this total enzymatic shutdown strips local repair cells of the baseline signals required to orchestrate tissue regeneration.   

Curcumin avoids this indiscriminate pathway paralysis by acting upstream on master transcriptional control switches rather than directly neutralizing isolated enzymes. Its primary therapeutic mechanism centers on the inhibition of Nuclear Factor-kappa B (NF-kB) and Activator Protein-1 (AP-1) signaling networks. Under acute stress or chronic inflammatory loads, the NF-kB protein complex is released from its cytoplasmic inhibitor, IkBa, and translocates directly into the cell nucleus, where it drives the transcription of catabolic cytokines such as interleukin-1 beta (IL-1ß), tumor necrosis factor-alpha (TNF-a), and interleukin-6 (IL-6). Curcumin blocks the phosphorylation and degradation of IkBa, effectively keeping NF-kB trapped in the cytoplasm. By preventing this nuclear entry, curcumin attenuates the expression of pro-inflammatory cytokines and downstream matrix-degrading enzymes while preserving baseline physiological functions. Furthermore, curcumin activates the nuclear factor erythroid 2-related factor 2 (Nrf2) and antioxidant response element (ARE) pathways, which upregulate endogenous cellular antioxidants to neutralize destructive reactive oxygen species (ROS) that induce cell death in injured joints.   

The Mechanisms of NSAID-Induced Inhibition in Cartilage and Tendon Repair

Cartilage maintenance depends on chondrocytes, the sole cell type residing within articular joints, which are responsible for generating and maintaining the extracellular matrix of Type II collagen and water-binding proteoglycans such as aggrecan. Because adult articular cartilage lacks a direct vascular network, major defect repair relies heavily on the recruitment and chondrogenic differentiation of subchondral mesenchymal stem cells (MSCs) through endochondral ossification. Experimental evaluations demonstrate that systemic or intra-articular NSAID exposure halts this regenerative differentiation. Both nonselective NSAIDs and selective COX-2 inhibitors interfere with chondrocyte maturation and prevent successful tissue integration following cartilage transplantation or microfracture procedures.  At the cellular level, common NSAIDs - including indomethacin, ketorolac, and diclofenac - induce cell cycle arrest in chondrocytes by blocking transition from the resting G0 phase to the proliferative G1.

phase, substantially reducing viable cell numbers. Concurrently, NSAIDs downregulate Bone Morphogenetic Protein-2 (BMP-2), an essential anabolic signaling molecule that orchestrates matrix synthesis. Histological analyses in animal models reveal that NSAID administration causes a marked loss of extracellular proteoglycan content and widespread chondrocyte depletion, yielding elevated modified Mankin scores that signify advanced structural degeneration. In layman's terms, proteoglycans serve as water-absorbing structural sponges that grant cartilage its elastic shock absorption. When NSAIDs deplete these molecules, the joint surface dries out, becomes brittle, and rapidly wears down under routine mechanical friction.   

Tendon healing is similarly susceptible to disruption by NSAIDs. Tendons operate as high-tensile structural cables composed of longitudinally arranged Type I collagen fibers, maintained by specialized fibroblasts termed tenocytes and tenoblasts. Healing after acute rupture or chronic tear progresses through an initial inflammatory phase, followed by a proliferative phase of cell migration, and culminates in a lengthy remodeling phase of collagen alignment. In vitro and in vivo studies establish that NSAIDs directly suppress the migration and proliferative capacity of tenocytes during the critical early healing window. Without an adequate cellular workforce migrating into the wound bed, provisional collagen scaffolding cannot be synthesized effectively.   

The disruption is particularly pronounced at the enthesis, the specialized fibrocartilaginous junction where soft tendon inserts into rigid bone. Re-establishing this transition zone requires coordinated bone remodeling and chondrogenic differentiation, both of which are hindered by COX inhibition. In animal rotator cuff repair models, early administration of NSAIDs significantly delays collagen fiber organization and impairs mechanical integration at the insertion site, resulting in a measurable decline in load-to-failure strength and overall tendon toughness. Furthermore, while prolonged inflammation contributes to pathological degeneration, the transient synthesis of PGE2 during the initial hours following injury is essential for regulating localized microvascular flow and hyperemic nutrient delivery. By eliminating this early prostanoid pulse, NSAIDs starve the repair zone of oxygen and circulating factors precisely when the cellular metabolic demand is highest.   

Beyond direct biochemical cytotoxicity, systemic NSAIDs introduce a physical hazard known as analgesic arthropathy. In musculoskeletal biomechanics, pain functions as a protective feedback mechanism, forcing the patient to unload an injured joint or limb to prevent structural overload. By effectively blunting the pain reflex while simultaneously undermining the cellular synthesis of proteoglycans and collagen, NSAIDs create a deceptive state of perceived recovery. Patients prematurely resume unrestricted weight-bearing and strenuous activity, placing substantial, uncompensated mechanical forces onto compromised cartilage surfaces and unhealed tendon fibers. Over time, this recurring mechanical trauma accelerates joint space narrowing, promotes microfractures in the subchondral plate, and hastens functional joint breakdown.   

Chondroprotective and Tenogenic Mechanisms of Curcumin

In articular cartilage, curcumin acts as a direct chondroprotective agent by dismantling the catabolic cascade induced by pro-inflammatory cytokines. When joint tissues are exposed to elevated IL-1ß and TNF-a, chondrocytes are provoked to synthesize matrix metalloproteinases - specifically collagenases such as MMP-1, MMP-3, and MMP-13 - along with aggrecanases like ADAMTS5. These enzymes function like enzymatic shears, systematically slicing through structural Type II collagen strands and degrading aggrecan cores. Curcumin suppresses the transcription and secretion of MMP-1, MMP-3, MMP-13, and ADAMTS5 by neutralizing NF-kB and AP-1 activation. Concurrently, it upregulates Cbp/p300 Interacting Transactivator with ED-rich tail 2 (CITED2), an essential transcriptional regulator that represses matrix metalloproteinases at the genomic level.   

In addition to halting extracellular degradation, curcumin protects chondrocytes from inflammatory apoptosis. Exposure to oxidative stress and inflammatory cytokines typically triggers programmed cell death by activating the intrinsic caspase cascade. Curcumin suppresses this apoptotic pathway by reducing the cleavage of executioner caspase-3, downregulating the pro-apoptotic factor Bax, and elevating anti-apoptotic Bcl-2 expression. Microscopic and histological analyses of osteoarthritic cartilage treated with curcumin consistently show robust Safranin O staining, intact surface regularity, preserved chondrocyte density, and significantly reduced Osteoarthritis Research Society International (OARSI) degradation scores.   

Within tendon biology, curcumin promotes active tissue regeneration (tenogenesis) rather than inert scar formation. In animal models of tendon rupture and surgical repair, curcumin guides tendon-derived stem and progenitor cells (TSPCs) toward mature tenocyte differentiation. This lineage-specific differentiation is orchestrated primarily through activation of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) and Wnt/ß-catenin signaling cascades. As stem cells commit to the tenogenic pathway, they significantly upregulate crucial structural and phenotypic markers, including epithelial cell adhesion molecule (EpCAM), tenomodulin, and the master tendon transcription factor Scleraxis.   

Through this guided differentiation, curcumin supports the preferential synthesis and organized deposition of high-tensile Type I collagen fibers, the primary architectural building blocks of healthy tendons. Injured tendons typically fill with disorganized, loose Type III collagen, which forms a structurally inferior, compliant scar. Curcumin supplementation promotes the progressive maturation from primitive Type III collagen to densely packed, parallel Type I collagen fibrils, restoring native tensile strength and mechanical breaking force.   

A major clinical challenge following tendon surgery is the development of peritendinous adhesions, in which excessive fibrotic scar tissue binds the healing tendon to its synovial sheath, restricting range of motion and joint gliding. Postoperative tendon repair involves a balance between extrinsic healing (in which exterior fibroblasts infiltrate the defect and deposit messy scar tissue) and intrinsic healing (in which tenocytes within the tendon substance reconstruct the matrix). Curcumin suppresses excessive peritendinous inflammation and extrinsic fibrosis while accelerating intrinsic tenocyte repair. Biomechanical testing confirms that local or systemic curcumin administration yields lower adhesion scores, increased gliding distances, and superior functional mobility without sacrificing structural load-bearing capacity.   

Comparative Clinical Efficacy and Systemic Safety Profiles

In randomized, active-controlled clinical trials of knee osteoarthritis, optimized curcumin preparations have demonstrated clinical pain reduction and functional recovery comparable to standard therapeutic doses of NSAIDs. In a randomized, open-label parallel-arm study evaluating 139 patients with symptomatic knee osteoarthritis, subjects received either 500 mg of a bio-enhanced curcumin extract three times daily or 50 mg of diclofenac sodium twice daily for 28 consecutive days. Patients treated with curcumin demonstrated comparable improvements in pain intensity on the Visual Analogue Scale (VAS) and functional scores on the Knee Injury and Osteoarthritis Outcome Score (KOOS) at days 14 and 28, showing no statistically significant difference in therapeutic efficacy compared to diclofenac.   

However, the systemic tolerability profiles between the treatments diverged markedly. Overall adverse events occurred in only 13% of the curcumin group compared to 38% of the diclofenac cohort. In the diclofenac arm, 28% of patients developed dyspeptic symptoms severe enough to require concurrent treatment with H2-receptor antagonists or proton pump inhibitors to prevent mucosal ulceration, whereas no patients in the curcumin cohort required gastroprotective intervention. Furthermore, the curcumin cohort experienced a significant reduction in flatulence and digestive discomfort, demonstrating beneficial gastric and intestinal cytoprotective effects.   

These safety observations are consistent across broader systematic reviews and meta-analyses. Nonsteroidal anti-inflammatory agents inherently compromise gastrointestinal integrity by systematically depleting cytoprotective prostaglandins, leaving the gastric epithelium vulnerable to acid erosion and hemorrhage. In addition, systemic inhibition of renal and vascular COX enzymes by NSAIDs reduces renal perfusion and disrupts the balance between prostacyclin and thromboxane, elevating the risk of fluid retention, hypertension, and adverse cardiovascular thrombotic events. Curcumin does not suppress these physiological prostanoid pathways, making it free from ulcerogenic, nephrotoxic, and cardiotoxic properties at therapeutic dosages.   

A longstanding limitation of standard curcumin supplementation in clinical settings has been its low oral bioavailability. Native curcuminoids are highly lipophilic, poorly soluble in aqueous gastric fluids, and subject to rapid hepatic and intestinal phase II metabolism into inactive glucuronides and sulfates, leading to swift biliary and fecal excretion. Consequently, raw culinary turmeric powders struggle to achieve the therapeutic systemic circulating concentrations required to reach poorly vascularized joint and tendon compartments. Modern pharmacognosy has addressed this pharmacodynamic hurdle through advanced delivery formulations. Modern strategies - such as co-administration with the natural alkaloid piperine (which inhibits hepatic glucuronidation), micellar dispersions, phytosomal phospholipid complexes, and bio-enhanced submicron dispersions - elevate systemic blood bioavailability by ten- to thirty-fold compared to unformulated extracts. These modern delivery platforms ensure that therapeutic concentrations reach synovial fluid, subchondral bone, and fibrous tendon sheaths without requiring excessive oral dosing.   

Conclusions and Translational Clinical Implications

In contrast, curcumin provides a tissue-preserving alternative that decouples pain and inflammation control from cellular suppression. Operating upstream at the level of NF-kB and AP-1 transcriptional activation, curcumin attenuates the expression of pro-inflammatory cytokines while leaving the physiological baseline of cellular metabolism intact. In cartilage, it actively represses the matrix-degrading enzymes MMP-1, MMP-3, MMP-13, and ADAMTS5, maintains water-binding proteoglycan content, and protects chondrocytes from inflammatory apoptosis. In damaged tendons, curcumin stimulates tenogenic differentiation of local stem cells via PI3K/Akt signaling, supports the proper maturation of dense Type I collagen fibers, and prevents restrictive peritendinous scar adhesions, preserving both joint mobility and mechanical breaking strength.   

From a translational perspective, these findings indicate that clinical protocols should reconsider relying on continuous NSAIDs as the default intervention for connective tissue injuries, post-surgical recovery, and chronic degenerative conditions. Where synthetic NSAIDs are deemed necessary, their use should be confined to short-term acute flare-ups to avoid interrupting early tissue remodeling. For long-term joint preservation, ongoing tendinopathy rehabilitation, and chronic osteoarthritis management, optimized bio-enhanced curcumin formulations deliver pain relief and functional restoration comparable to conventional pharmaceuticals, all while preserving the biological processes required for lasting musculoskeletal repair.   

References:

pmc.ncbi.nlm.nih.gov

NSAID therapy effects on healing of bone, tendon, and the enthesis

Opens in a new window

pmc.ncbi.nlm.nih.gov

The Detrimental Effects of Systemic Ibuprofen Delivery on Tendon

Opens in a new window

pmc.ncbi.nlm.nih.gov

Conservative management of symptomatic knee osteoarthritis - PMC

Opens in a new window

pmc.ncbi.nlm.nih.gov

Positives and negatives of nonsteroidal anti-inflammatory drugs in

Opens in a new window

researchgate.net

(PDF) Conservative management of symptomatic knee osteoarthritis

Opens in a new window

pubmed.ncbi.nlm.nih.gov

Non-steroidal anti-inflammatory drugs influence cartilage healing

Opens in a new window

pmc.ncbi.nlm.nih.gov

Is Curcumine Useful in the Treatment and Prevention of ... - PMC - NIH

Opens in a new window

pmc.ncbi.nlm.nih.gov

Efficacy and mechanisms of curcumin in the treatment of osteoarthritis

Opens in a new window

pubmed.ncbi.nlm.nih.gov

Biological actions of curcumin on articular chondrocytes - PubMed

Opens in a new window

pmc.ncbi.nlm.nih.gov

Curcumin slows osteoarthritis progression and relieves ... - PMC - NIH

Opens in a new window

pmc.ncbi.nlm.nih.gov

Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect

Opens in a new window

pmc.ncbi.nlm.nih.gov

Anti-inflammatory management for tendon injuries - friends or foes?

Opens in a new window

pubmed.ncbi.nlm.nih.gov

The mechanistic role of curcumin on matrix metalloproteinases in

Opens in a new window

pmc.ncbi.nlm.nih.gov

Therapeutic effects of turmeric or curcumin extract on pain and

Opens in a new window

pmc.ncbi.nlm.nih.gov

Curcumin inhibits chondrocyte apoptosis and inflammation in ... - PMC

Opens in a new window

pmc.ncbi.nlm.nih.gov

Analysis of the mechanism of curcumin against osteoarthritis using

Opens in a new window

pmc.ncbi.nlm.nih.gov

Synergistic enhancement of tendon-to-bone healing via anti ... - PMC

Opens in a new window

pmc.ncbi.nlm.nih.gov

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Opens in a new window

pubmed.ncbi.nlm.nih.gov

Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis

Opens in a new window

pubmed.ncbi.nlm.nih.gov

A randomized, pilot study to assess the efficacy and safety ... - PubMed

Opens in a new window

pubmed.ncbi.nlm.nih.gov

Effectiveness of curcuminoids in the treatment of knee osteoarthritis

Opens in a new window

journalijar.com

THE EFFECTS OF TRADITIONAL STRENGTHENING EXERCISES

Opens in a new window

acpjournals.org

Putting Some Muscle into Osteoarthritis | Annals of Internal Medicine

Opens in a new window

pubmed.ncbi.nlm.nih.gov

Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect

Opens in a new window

pmc.ncbi.nlm.nih.gov

Calebin A, a Compound of Turmeric, Down-Regulates Inflammation

Opens in a new window

pmc.ncbi.nlm.nih.gov

The Effect of Non-Steroidal Anti-Inflammatory Drugs on Tendon-to

Opens in a new window

advancedhealth.ca

Chiropractor in Toronto, ON, Canada :: Head and Neck Pain

Opens in a new window

pmc.ncbi.nlm.nih.gov

Investigation of the association of long-term NSAID use with ... - PMC

Opens in a new window

pmc.ncbi.nlm.nih.gov

Curcumin Improves Functional Recovery of Ruptured Tendon by

Opens in a new window

pmc.ncbi.nlm.nih.gov

Chemically modified curcumin (CMC2.24) alleviates osteoarthritis

Opens in a new window

pmc.ncbi.nlm.nih.gov

Curcumin improves age-related and surgically induced osteoarthritis

Opens in a new window

researchgate.net

(PDF) Curcumin Improves Functional Recovery of Ruptured Tendon

Opens in a new window

pmc.ncbi.nlm.nih.gov

Investigation of the effects of umbilical cord-derived mesenchymal

Opens in a new window

pmc.ncbi.nlm.nih.gov

Effect of curcumin-loaded polycaprolactone scaffold on Achilles

Opens in a new window

pmc.ncbi.nlm.nih.gov

Controlled release of curcumin from curcumin-loaded nanomicelles

Opens in a new window

pmc.ncbi.nlm.nih.gov

Efficacy and safety of combination of curcuminoid complex ... - PMC

Opens in a new window

pubmed.ncbi.nlm.nih.gov

The efficacy of Curcuma Longa L. extract as an adjuvant therapy in

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6653)

Date: September 10, 2026 10:57 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Ultimate Guide to Cellular Longevity: NAD+, Methylation, and Senolytics

Introduction: Understanding Cellular Aging and Energy Decline

Cellular aging is characterized by interconnected biological disruptions known as the hallmarks of aging. These encompass genomic instability, epigenetic alterations, mitochondrial decay, loss of proteostasis, and cellular senescence. Rather than operating as isolated occurrences, these phenomena establish a self-reinforcing degenerative cycle: declining cellular power generation impairs enzymatic genetic repair, promoting the accumulation of damaged cells that enter irreversible growth arrest and poison surrounding healthy tissues. Mitigating cellular aging requires examining how microscopic bioenergetic pathways deteriorate and evaluating how targeted nutritional and biochemical interventions can restore cellular homeostasis.

The Role of Mitochondria and ATP Production

A youthful cell functions like an efficient municipal power grid, dynamically matching energetic demands with immediate ATP output. However, as biological aging progresses, mitochondrial efficiency declines. The electron transport chain becomes structurally leaky, inadvertently shedding electrons that react with ambient molecular oxygen to produce reactive oxygen species (ROS). While regulated levels of ROS participate in vital intracellular signaling, chronic excess induces widespread oxidative stress.

Mitochondria are exceptionally vulnerable to this oxidative burden because they carry their own circular genetic material, known as mitochondrial DNA (mtDNA). Unlike nuclear DNA, mtDNA lacks the protective shielding of histone proteins and possesses rudimentary repair systems. As a result, mtDNA sustains cumulative oxidative damage, encoding increasingly defective electron transport chain proteins. This dynamic generates a bioenergetic deficit: degraded mitochondria synthesize progressively less ATP while emitting greater volumes of damaging free radicals. Deprived of optimal ATP reserves, cells lack the energy necessary to drive vital enzymatic repair cascades, accelerating structural degeneration and functional exhaustion.

How Cellular Senescence Accelerates the Aging Process

Senescent cells, colloquially known as "zombie cells," enter a state of permanent growth arrest while actively resisting programmed cell death (apoptosis). Over time, these cells accumulate within adipose depots, skeletal muscle, the vascular endothelium, and major organs, largely because immune surveillance and clearance pathways simultaneously lose functional efficiency.

The systemic danger of senescent cells stems from their secretome. Rather than remaining biologically inert, senescent cells develop a hyperactive secretory state termed the Senescence-Associated Secretory Phenotype (SASP). The SASP is a destructive mixture of pro-inflammatory cytokines, chemokines, extracellular matrix-degrading matrix metalloproteinases (MMPs), and reactive oxygen species.

Through this toxic secretome, even a small burden of senescent cells can impair whole-tissue architecture. SASP factors degrade surrounding structural proteins, induce insulin resistance in neighboring metabolic cells, and biochemically force adjacent healthy cells into secondary senescence. This persistent paracrine signaling fuels chronic, sterile, low-grade systemic inflammation, termed "inflammaging," which accelerates systemic tissue degeneration and elevates susceptibility to degenerative age-related pathologies.

Nicotinamide Riboside (NR) and the NAD+ Salvage Pathway

The Biochemistry of NAD+ Depletion Over Time

The primary enzymatic driver of age-related NAD+ destruction is CD38, a membrane-bound glycohydrolase expressed on immune cells that is upregulated in response to chronic SASP exposure. Concurrently, lifelong genotoxic damage causes persistent activation of Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that cleaves the glycosidic bonds of NAD+ to assemble branched poly(ADP-ribose) chains at DNA lesion sites. Because PARP-1 consumes NAD+ without directly recycling the molecule, chronic DNA damage depletes intracellular NAD+ pools, impairing bioenergetics and limiting sirtuin activity.

How NR Efficiently Boosts Cellular NAD+ Levels

The salvage pathway recycles the breakdown product nicotinamide (NAM), which is released whenever NAD+-consuming enzymes execute their functions. Under normal conditions, cells convert free nicotinamide into nicotinamide mononucleotide (NMN) via the rate-limiting enzyme nicotinamide phosphoribosyltransferase (NAMPT), after which NMN adenylyltransferases (NMNAT1–3) complete the conversion into NAD+. However, NAMPT expression declines with advancing age, chronic inflammation, and metabolic stress, limiting the recycling capacity of the cell.

Nicotinamide Riboside (NR) is a naturally occurring pyridine nucleoside that bypasses this enzymatic bottleneck. Upon cellular entry via equilibrative nucleoside transporters, NR is directly phosphorylated into NMN by nicotinamide riboside kinases (NRK1 and NRK2) using a single molecule of ATP. Because the NRK pathway remains intact and robust across the lifespan, NR provides an efficient alternative entry point into the NAD+ salvage cascade.

Clinical evaluations in humans confirm the safety, bioavailability, and pharmacokinetics of oral NR supplementation. Randomized, double-blind, placebo-controlled trials reveal that oral NR chloride produces dose-dependent increases in steady-state whole blood NAD+ concentrations. Dosing regimens of 100 mg, 300 mg, and 1,000 mg daily elevate blood NAD+ levels by approximately 22%, 51%, and up to 142%, respectively, within two weeks of administration, maintaining these elevations throughout continuous use. High-resolution metabolomic analyses also demonstrate parallel elevations in nicotinic acid adenine dinucleotide (NAAD), establishing it as a reliable biomarker of active intracellular NAD+ synthesis without hepatic or systemic toxicity.

Sirtuin Activation and DNA Repair Mechanisms

In the nucleus, SIRT1 coordinates defense against cellular decline. When activated by restored NAD+ levels, SIRT1 deacetylates peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1a), the master transcriptional coactivator of mitochondrial biogenesis. This deacetylation stimulates mitochondrial replication and assembly, expanding functional respiratory capacity. Concurrently, SIRT1 deacetylates the p65 subunit of nuclear factor-kappa B (NF-kB), suppressing the transcription of pro-inflammatory cytokines. In the mitochondria, SIRT3 utilizes NAD+ to deacetylate metabolic enzymes and superoxide dismutase 2 (SOD2), enhancing the organelle's capacity to neutralize reactive oxygen species.

At the same time, cellular NAD+ levels directly regulate genomic integrity through PARP-1. When genotoxic stress or oxidative damage induces single- or double-strand DNA breaks, PARP-1 binds to the damaged termini using its zinc-finger domains. Bound PARP-1 hydrolyzes NAD+ to synthesize extensive, negatively charged poly(ADP-ribose) polymers on itself and adjacent histones. This modification relaxes chromatin architecture and establishes an electrostatic scaffold that recruits base excision repair and homologous recombination complexes.

Recent discoveries demonstrate close crosstalk between sirtuins and PARP-1 during DNA repair. PARP-1 recruits SIRT1 to double-strand breaks, where SIRT1 deacetylates the chromatin-remodeling ATPase BRG1 to displace nucleosomes and facilitate homologous recombination. However, because PARP-1 and SIRT1 draw from the same intracellular NAD+ pool, severe NAD+ depletion forces a biological compromise: PARP-1 consumes the scarce remaining cofactor to address DNA damage, leaving sirtuins deactivated. Restoring NAD+ via NR prevents this deficit, enabling concurrent genomic repair and sirtuin-mediated metabolic defense.

Quercetin: A Powerful Senolytic and mTOR Regulator

Clearing Senescent "Zombie" Cells from Tissues

Quercetin is a polyphenolic flavonoid found in capers, red onions, apples, and the flower buds of Sophora japonica. Beyond its classical antioxidant properties, quercetin functions as a senolytic compound that exerts multi-target inhibitory effects across the SCAP network. By inhibiting the upstream PI3K/Akt survival axis and downregulating anti-apoptotic defenses, quercetin disrupts the signaling that protects senescent cells from intrinsic apoptosis. Deprived of these survival signals, senescent cells undergo programmed cell death.

Preclinical studies demonstrate that senolytic protocols utilizing quercetin - often combined with the tyrosine kinase inhibitor dasatinib - reduce senescent cell burden across multiple tissues. This targeted clearance lowers circulating SASP factors, attenuates tissue fibrosis, restores endothelial reactivity, and improves functional health span. By removing senescent cells, quercetin mitigates the primary driver of chronic, low-grade inflammaging.

Modulating the mTOR Pathway for Optimal Autophagy

Autophagy is an intracellular degradation system that packages damaged organelles, misfolded protein aggregates, and biological debris into double-membraned autophagosomes for lysosomal degradation and recycling. A specialized branch of this pathway, mitophagy, selectively targets and clears damaged mitochondria. In modern metabolic conditions characterized by continuous caloric intake, mTORC1 can remain persistently active. This persistent signaling suppresses autophagy, causing damaged organelles and toxic aggregates to accumulate within tissues.

Quercetin functions as a natural modulator of mTOR signaling. By inhibiting upstream PI3K/Akt signaling and activating intracellular energy sensors, quercetin attenuates overactive mTORC1, mimicking the metabolic effects of caloric restriction. This down-regulation relieves inhibition on the ULK1 autophagy initiation complex, stimulating both general autophagy and mitophagy. As autophagy proceeds, cells clear protein aggregates and eliminate damaged mitochondria, supporting cellular longevity and proteostasis.

Enhancing Absorption: Phytosomes and Dietary Fats

To address these pharmacokinetic limitations, advanced delivery systems such as phytosomes were engineered. A phytosome is a 100% food-grade molecular complex where individual polyphenolic molecules are bound to dietary phospholipids, typically sunflower-derived phosphatidylcholine. Unlike a classical liposome - which encapsulates water-soluble compounds inside an aqueous core enclosed by a lipid bilayer - a phytosome forms an amphiphilic complex at the molecular level.

The polar head of the phosphatidylcholine molecule forms hydrogen bonds with the hydroxyl groups of the quercetin molecule, while its lipophilic fatty acid tails extend outward. This structural arrangement shields the polar regions of the flavonoid, creating a lipid-compatible complex that integrates smoothly into the intestinal mucosa.

The Importance of Methylation in Healthy Aging

Vitamin B-Complex and Choline as Essential Methyl Donors

At the center of this pathway sits S-adenosylmethionine (SAM), the universal methyl donor in human biology. When a methyltransferase enzyme transfers a methyl group from SAM to an acceptor molecule, SAM is converted into S-adenosylhomocysteine (SAH). SAH functions as a potent competitive inhibitor of intracellular methyltransferases. To maintain functional methylation, SAH is rapidly hydrolyzed into homocysteine, a sulfur-containing amino acid that must be remethylated or cleared through transsulfuration.

Homocysteine clearance proceeds through two distinct remethylation pathways. The primary route operates across most tissues via the enzyme methionine synthase, which requires vitamin B12 in its active methylcobalamin form. Methionine synthase transfers a methyl group from 5-methyltetrahydrofolate (5-MTHF, the active form of folate) to homocysteine, regenerating methionine. The ongoing production of 5-MTHF depends on the enzyme methylenetetrahydrofolate reductase (MTHFR), which utilizes riboflavin (vitamin B2) as a cofactor.

Alternatively, excess homocysteine can be routed into the transsulfuration pathway by vitamin B6 (as pyridoxal-5'-phosphate) to synthesize cystathionine, cysteine, and ultimately the antioxidant glutathione.

A secondary remethylation pathway, active predominantly in hepatic and renal tissues, bypasses folate entirely. In this route, dietary choline is oxidized to betaine (trimethylglycine or TMG). The enzyme betaine-homocysteine S-methyltransferase (BHMT) then transfers a methyl group from betaine directly to homocysteine, yielding methionine and dimethylglycine.

When dietary intake of active B-vitamins or choline is insufficient, or when genetic variations like MTHFR polymorphisms reduce pathway flux, the methylation cycle slows. Homocysteine accumulates in circulation, promoting vascular and neurological inflammation, while SAM reserves decline, restricting cellular methylation capacity.

Understanding DNA Methylation and Epigenetic Health

Under physiological conditions, DNA methylation maintains genomic stability and coordinates transcription. Methylation of promoter regions condenses chromatin, repressing transposable elements and silencing genes inappropriate for a given cell type. Conversely, hypomethylated promoters maintain an open chromatin state, allowing transcription factors to bind and initiate gene expression.

During biological aging, this epigenetic landscape undergoes progressive dysregulation, a phenomenon termed "epigenetic drift". Aging cells experience global hypomethylation alongside focal hypermethylation of specific gene promoters. Global loss of methyl tags destabilizes the genome, activating retrotransposons and pro-inflammatory pathways. Simultaneously, hypermethylation at targeted promoter sites silences critical tumor suppressor genes and DNA repair complexes.

This systematic change in DNA methylation patterns is consistent across populations, allowing researchers to develop molecular "epigenetic clocks". Algorithms such as the Horvath clock, PhenoAge, and GrimAge quantify biological age by profiling the methylation status of specific CpG sites across the genome. These clocks assess whether individuals are aging faster or slower than their chronological years. Ensuring a steady supply of methyl donors and preventing unnecessary SAM depletion supports DNMT activity, maintaining epigenetic patterns and genomic stability.

How the Methylation Cycle Impacts Energy and Cognitive Focus

A major consumer of methyl reserves is the endogenous synthesis of creatine. Approximately 40% of all SAM-derived methyl groups in the human body are utilized by guanidinoacetate N-methyltransferase (GAMT) in the liver to synthesize creatine. Creatine then translocates to the brain and skeletal muscle, where it is phosphorylated into phosphocreatine.

Phosphocreatine functions as a rapid energy buffer, donating a high-energy phosphate group to regenerate ADP into ATP in milliseconds during demanding physical or cognitive tasks. When methyl donor availability falls, endogenous creatine synthesis drops, depleting phosphocreatine reserves and increasing susceptibility to neuromuscular and cognitive fatigue.

Methylation is equally central to central nervous system architecture. SAM provides methyl groups to convert phosphatidylethanolamine into phosphatidylcholine, the predominant phospholipid comprising neuronal cell membranes and the myelin sheaths that insulate axons. Intact myelin preserves rapid action potential conduction throughout the nervous system.

Furthermore, free choline derived from this pathway is the direct precursor to acetylcholine, the neurotransmitter required for attention, working memory, and learning.

The methylation cycle also governs monoamine neurotransmitter metabolism. SAM is required for the synthesis of adrenaline (epinephrine) from noradrenaline, while catechol-O-methyltransferase (COMT) relies on SAM to degrade dopamine and norepinephrine within the prefrontal cortex. Sluggish methylation disrupts this balance, contributing to cognitive fatigue, mood variability, and impaired mental performance.

Building a Comprehensive Longevity Protocol

Synergizing NR, Quercetin, and Methylated B-Vitamins

This synergy is grounded in the direct biochemical intersection between the NAD+ salvage pathway and the methylation cycle. When high-dose NR is supplemented to boost systemic NAD+, sirtuins and PARP enzymes consume the newly synthesized cofactor, generating substantial quantities of free nicotinamide (NAM). This intracellular nicotinamide faces two primary metabolic fates: it can be recycled back into NAD+ through the NAMPT-dependent salvage loop, or it can be cleared via methylation.

When the influx of nicotinamide exceeds salvage recycling capacity, the excess is cleared to avoid feedback inhibition of sirtuin enzymes. To accomplish this, the enzyme nicotinamide N-methyltransferase (NNMT) transfers a methyl group from SAM directly onto nicotinamide, forming 1-methylnicotinamide (1-MNA/MNAM), which is subsequently excreted in urine.

Prolonged, high-dose precursor administration without nutritional methyl support can elevate NNMT flux, depleting intracellular SAM reserves. As methyl groups are consumed clearing nicotinamide, the cellular SAM-to-SAH ratio falls, which can elevate circulating homocysteine and reduce methyl availability for DNA methylation and neurotransmitter synthesis.

Co-administering a fully methylated B-complex alongside choline or betaine addresses this potential bottleneck. Providing active methyl donors (such as 5-MTHF, methylcobalamin, and betaine) maintains the one-carbon donor pool. Even during increased NNMT activity, SAM pools remain stable, protecting DNA methylation fidelity and maintaining homocysteine within safe parameters.

Quercetin reinforces this protocol through complementary mechanisms. By clearing senescent cells and reducing SASP-mediated inflammation, quercetin downregulates CD38, the primary enzyme responsible for age-related NAD+ degradation. Suppressing CD38 prevents unnecessary breakdown of newly synthesized NAD+, enhancing the efficiency of NR supplementation.

Furthermore, while NR provides the NAD+ necessary to activate SIRT1-driven mitochondrial biogenesis, quercetin concurrently modulates mTORC1 to stimulate autophagy. This coordinated action ensures that newly generated mitochondria operate in an environment cleared of proteotoxic cellular debris.

The Crucial Role of Magnesium Glycinate and Zinc in Cellular Function

Magnesium serves as an obligatory cofactor in over 300 enzymatic reactions, primarily through its interaction with ATP. In biological systems, ATP exists predominantly as a chelate with a divalent magnesium ion, forming biologically active Mg2+ -ATP.

Every enzymatic reaction that synthesizes, transfers, or consumes cellular energy - including the enzymes of the NAD+ salvage pathway (NRK and NMNAT) and DNA polymerases - strictly requires Mg2+ -ATP as its substrate. Magnesium deficiency impairs these phosphorylation reactions, reducing the cellular utilization of NAD+ precursors.

Additionally, magnesium is an essential cofactor for the enzymes that activate dietary B-vitamins into their active forms. Supplying magnesium as magnesium glycinate provides high gastrointestinal bioavailability, minimal laxative effect, and yields glycine to support inhibitory neurotransmission and restful sleep.

Zinc serves as a vital structural component for more than 3,000 human transcription factors and enzymatic proteins. Its most prominent structural role in longevity occurs within zinc-finger motifs. These are specialized protein conformations stabilized by a zinc ion coordinated to cysteine and histidine residues.

The DNA damage sensor PARP-1 utilizes three zinc-finger domains to identify, track, and physically bind to single- and double-strand DNA breaks. Without adequate intracellular zinc, PARP-1 cannot properly assemble or dock onto damaged chromosomes, impairing DNA repair and increasing genomic instability.

Zinc is also an obligatory structural component of copper/zinc superoxide dismutase (Cu/Zn-SOD or SOD1), the primary cytosolic antioxidant enzyme that dismutates superoxide radicals into hydrogen peroxide, protecting mitochondrial membranes and nuclear DNA from premature senescence.

Integrating Prebiotics (like Acacia and Inulin) for Gut-Derived Longevity Markers

The gut epithelium consists of a single-cell monolayer sealed by tight junction proteins, including zonula occludens-1 (ZO-1), occludin, and claudins. When this physical barrier is disrupted by poor dietary fiber intake or dysbiosis, gut permeability increases.

This allows lipopolysaccharide (LPS), a component of the outer membrane of Gram-negative bacteria, to enter the portal and systemic circulation. The resulting "metabolic endotoxemia" activates Toll-like receptor 4 (TLR4) on immune cells, inducing NF-kB and systemic pro-inflammatory cytokine production. This persistent gut-derived inflammation exacerbates the SASP, accelerates tissue senescence, upregulates CD38, and drains systemic NAD+ reserves.

These short-chain fatty acids, particularly butyrate, exert direct protective effects on systemic longevity. Butyrate provides the primary metabolic fuel for colonic epithelial cells, supplying more than 70% of their baseline energy needs and supporting mitochondrial function within colonocytes.

Furthermore, SCFAs upregulate the expression of epithelial tight junction proteins (ZO-1, occludin, and claudin-1), restoring intestinal barrier integrity and preventing the translocation of inflammatory LPS into systemic circulation.

Systemically absorbed butyrate also functions as an endogenous histone deacetylase (HDAC) inhibitor, suppressing pro-inflammatory gene expression and supporting regulatory T cell (T_reg) development. Reducing metabolic endotoxemia dampens systemic inflammation, protecting vascular function and preventing premature NAD+ depletion.

Conclusion: The Integrated Cellular Longevity Matrix

Quercetin Phytosome clears senescent cells and modulates mTORC1, stimulating autophagy while dampening the inflammatory SASP cascade that accelerates CD38-mediated NAD+ destruction.

Methylated B-vitamins, active folate, and choline replenish SAM reserves, balancing the methyl requirements of NNMT-mediated nicotinamide clearance, preserving epigenetic DNA methylation, and maintaining neurotransmitter production.

Magnesium glycinate and zinc provide the structural and catalytic foundation required for ATP utilization, B-vitamin activation, and PARP-1 zinc-finger DNA repair docking.

Finally, prebiotic fibers generate short-chain fatty acids like butyrate, reinforcing the intestinal barrier and preventing metabolic endotoxemia from fueling systemic inflammation.

By coordinating energy replenishment, cellular waste clearance, epigenetic maintenance, and the suppression of systemic inflammation, this unified approach directly addresses the underlying drivers of cellular aging to support long-term physiological vitality.

--
Content Put together by Darrell Miller CEO of VitaNet LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6650)

Date: November 05, 2025 11:58 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Can Akkermansia Muciniphila help the body fight leaky gut?

Yes, based on a significant body of research, Akkermansia muciniphila is strongly associated with helping the body combat "leaky gut" by strengthening the intestinal barrier.

"Leaky gut" is the common term for a medical condition known as increased intestinal permeability. This happens when the lining of your gut is damaged, allowing bacteria, toxins, and undigested food particles to "leak" from your intestines into your bloodstream, which can trigger inflammation and other health issues.

Akkermansia muciniphila (or A. muciniphila) is a beneficial bacterium that lives in the mucus layer of your intestines. It plays a direct and crucial role in keeping this gut barrier strong and healthy.

How Akkermansia Helps Fight Leaky Gut

1. Reinforces the Mucus Layer: This is its most unique function.
   • A. muciniphila feeds on mucin, the main component of the gut's protective mucus layer.
   • This "feeding" process acts as a signal, stimulating the specialized cells in your intestinal wall (goblet cells) to produce more mucin.
   • This continuous turnover thickens and strengthens the mucus barrier, creating a more robust defense against harmful substances.
2. Strengthens "Tight Junctions":
   • The cells of your intestinal lining are sealed together by proteins called "tight junctions." In a leaky gut, these junctions become loose.
   • A. muciniphila has been shown to increase the expression of these tight junction proteins, helping to "seal the leaks" and keep the intestinal barrier intact.
3. Produces Beneficial Compounds:
   • As A. muciniphila digests mucin, it produces short-chain fatty acids (SCFAs), such as acetate.
   • These SCFAs serve as an energy source for other beneficial bacteria and for the cells lining your colon, helping to keep them healthy and functional.

The Bigger Picture

• Obesity
• Type 2 diabetes
• Inflammatory bowel disease (IBD)
• Metabolic syndrome

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6624)

Date: May 29, 2024 11:28 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Role of Vitamin B12 in Energy Production

The Role of Vitamin B12 in Energy Production

Vitamin B12, or cobalamin, is crucial for red blood cell production, DNA synthesis, and nervous system health. Among its many roles, one of the most vital is its contribution to energy production and metabolism. This article delves into how Vitamin B12 affects energy levels, with a particular focus on its importance for vegetarians and vegans.

Understanding Vitamin B12

Vitamin B12 is a water-soluble vitamin that is naturally found in animal products such as meat, dairy, and eggs. It is primarily responsible for converting food into ATP (adenosine triphosphate), which the body uses for energy. B12 is also crucial in the formation of red blood cells, which carry oxygen to every part of the body, and in maintaining the health of nerve cells.

The Science Behind Energy Production

Role in Metabolism

Vitamin B12 is a key player in metabolism, a complex set of chemical reactions in our body that convert food into energy. One of the primary ways B12 contributes to metabolism is through its involvement in the Krebs cycle, a series of reactions that produce ATP (adenosine triphosphate), the body's primary energy currency. During the Krebs cycle, Vitamin B12 helps convert fats and proteins into energy, ensuring that the body has a constant supply of fuel to perform everyday tasks.

DNA Synthesis and Cell Division

Vitamin B12 is also essential for DNA synthesis and cell division. It works closely with folate (Vitamin B9) to synthesize DNA during cell division. Rapidly dividing tissues, such as red blood cells, require an adequate supply of B12. A deficiency in this vitamin can lead to megaloblastic anemia, a condition where red blood cells are larger than normal and not as effective in transporting oxygen, thereby causing fatigue and Weakness.

The Challenge for Vegetarians and Vegans

B12 Sources

One of the significant challenges for vegetarians and vegans is getting enough Vitamin B12, as it is predominantly found in animal products. Plant-based diets generally lack this vitamin, putting individuals at risk of deficiency. However, several fortified foods and supplements can help prevent this deficiency.

Fortified Foods and Supplements

Many plant-based milk alternatives, breakfast cereals, and nutritional yeasts are now fortified with Vitamin B12. For instance, a cup of fortified soy milk can provide about 50% of the daily recommended intake of B12. Additionally, B12 supplements are readily available and can be an effective way for vegetarians and vegans to ensure they get their daily dose. It's crucial to choose a supplement that meets the dietary needs and preferences of the individual.

Symptoms of Deficiency

A lack of Vitamin B12 can result in various health problems like fatigue, Weakness, constipation, loss of appetite, and weight loss. In severe cases, it may lead to neurological issues such as numbness and tingling in the hands and feet, balance difficulties, depression, confusion, and memory loss. Given these risks, it's essential for vegetarians and vegans to monitor their B12 levels.

Benefits of Adequate B12 Intake

Enhanced Energy Levels

Adequate intake of Vitamin B12 can significantly enhance energy levels. Since B12 is involved in converting food into ATP, sufficient levels of this vitamin can help ensure that the body efficiently produces and uses energy. Individuals who maintain appropriate B12 levels often report feeling more energetic and less fatigued.

Improved Metabolic Function

By ensuring a sufficient supply of B12, vegetarians and vegans can support their metabolic functions. A well-functioning metabolism is crucial for maintaining body weight, supporting muscle function, and ensuring overall vitality. Improved metabolic function also means better handling of the foods consumed, leading to more stable energy levels throughout the day.

Better Mental Health

Vitamin B12 is essential for producing neurotransmitters that regulate mood. Adequate levels of B12 can help prevent mental health issues such as depression and brain fog, which are often associated with fatigue and low energy levels. Regular intake of B12, either through diet or supplements, can contribute to better mental clarity and emotional well-being.

Optimal Nervous System Function

B12 is crucial in maintaining the myelin sheath, a protective coating around nerves. A healthy nervous system ensures that signals travel efficiently between the brain and the rest of the body. This not only helps in preventing neurological issues but also ensures that the body's energy systems operate smoothly.

How to Ensure Adequate B12 Intake

Regular Blood Tests

For vegetarians and vegans, regular blood tests are an effective way to monitor B12 levels. These tests can help identify a deficiency early on, allowing individuals to take corrective measures before any severe symptoms manifest.

Balanced Diet

A well-rounded, balanced diet that includes fortified foods can help meet the daily recommended intake of Vitamin B12. Incorporating a variety of B12-fortified foods into every meal ensures a steady supply of this vital nutrient.

Considering Supplements

For those who struggle to get enough Vitamin B12 through diet alone, supplements are an excellent option.

Choosing the Right Supplement: Methyl B12

When selecting a Vitamin B12 supplement, methylcobalamin, or methyl B12, is often recommended as the best form. It has superior bioavailability compared to cyanocobalamin, making it easier for the body to absorb and utilize. Methyl B12 doesn't need conversion in the body to be effective, leading to quicker uptake and immediate benefits.

For vegetarians and vegans at higher risk of B12 deficiency, methyl B12 is especially beneficial for maintaining optimal B12 levels effectively. Including this form in your supplement routine can boost energy, mental clarity, and support metabolic and nervous system functions.

Awareness and Education

Raising awareness about B12 is key for vegetarians and vegans to prevent deficiencies. Health programs can educate on maintaining adequate levels through diet and supplements.

Are You Ready For More Energy?

Vitamin B12's role in energy production and metabolism is indisputable. Vegetarians and vegans can struggle to get enough B12 from plant-based diets, but fortified foods and supplements offer solutions. Understanding B12's importance and taking action can boost energy, metabolism, and well-being. Regular monitoring, a balanced diet, and appropriate supplementation are key strategies to prevent deficiency and maintain optimal health.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6604)

Date: November 06, 2023 04:50 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Importance of Collagen for Your Health: Why You Should Care

The Importance of Collagen for Your Health: Why You Should Care

Have you ever heard about collagen? It might have been a buzzword in the beauty industry, but it's important to know that collagen is much more than just skin-deep. Collagen is actually a protein that plays a crucial role in providing structure, strength, and support to different parts of our bodies such as skin, bones, tendons, and ligaments. Lets explore the importance of collagen for your health, its different types and functions, the effects of collagen loss on the body, factors that affect collagen production, and how to boost collagen levels naturally.

Factors That Affect Collagen Production:

Collagen production declines naturally with aging, leading to visible signs of aging like wrinkles, sagging skin, and brittle nails. However, several lifestyle factors also contribute to collagen loss like smoking, consuming sugary foods, and excessive sun exposure. Medical conditions like scleroderma and Ehlers-Danlos syndrome also lead to reduced collagen production.

The Effects of Collagen Loss on the Body:

Collagen loss can have various detrimental effects on the body. One of the most visible effects is on the skin where collagen loss leads to wrinkles, fine lines, sagging, and dryness. Collagen loss also affects joints, resulting in pain and stiffness. Since collagen is crucial to maintaining bone structure, a decrease in collagen levels Weakens the bones and muscles, causing osteoporosis. Collagen is important for the digestive tract lining, so when the body lacks sufficient collagen, people could experience digestive issues.

Lifestyle Habits Leading to Collagen Loss:

Several lifestyle habits exacerbate the natural decline in collagen production, thereby speeding up the aging process and negatively affecting overall health. First among these is smoking. The chemicals present in cigarettes damage collagen and elastin, causing premature skin aging with characteristic wrinkles and sagging. Not only does smoking impact the skin, but it also affects collagen-rich organs and tissues, leading to various health problems.

Next is the consumption of excessive sugar and refined carbohydrates. A high-sugar diet interferes with collagen's ability to repair itself, leading to inflammation and collagen cross-linking that results in skin aging and joint discomfort. Refined carbohydrates spike blood sugar levels, encouraging the same damaging process.

Last but not least, ultraviolet (UV) light exposure, particularly from the sun, can also lead to significant collagen loss. UV light increases collagen breakdown by activating enzymes called matrix metalloproteinases that degrade collagen and elastin. This exposure results in photoaging of the skin, characterized by deep wrinkles, leathery texture, and pigmentation changes. Therefore, it's crucial to protect your skin from the sun by wearing SPF every day, even on cloudy days.

How to Boost Collagen Levels Naturally:

Fortunately, several natural ways can help boost collagen levels in your body. Maintaining a balanced diet rich in vitamins and minerals such as vitamin C, zinc, copper, and iron is key to boosting collagen levels. Vitamin C is vital in the production of collagen, which makes it an essential nutrient for the body. Excessive sun exposure and smoking lead to the accumulation of free radicals that damage collagen, so avoiding these is key. In addition, the topical use of skincare products like sunscreen and moisturizers protects and nourishes collagen and helps maintain healthy skin. Exercise such as weight training and yoga can help stimulate collagen synthesis, ensuring youthful-looking skin, healthy joints, and strong bones.

Common types of collagen!

• Type I Collagen: This is the most abundant type of collagen in the body. It's primarily responsible for providing structure to the skin, tendons, organs, and the bone matrix. It also plays a crucial role in wound healing.
• Type II Collagen: This type of collagen is primarily found in cartilage and serves as the main component of our joints. It's important for maintaining healthy joint movement and reducing the effects of joint-related aging.
• Type III Collagen: Often found alongside Type I, Type III collagen supports the structure of muscles, organs, and arteries. It's also a key component in the body's natural healing processes.
• Type IV Collagen: This type forms the basis of the cell basement membrane and plays a critical role in maintaining cell and tissue health by aiding filtration.
• Type V Collagen: This type of collagen is found in the surfaces of cells, hair, and placenta. It's important for various cellular processes, including the growth and development of cells and tissues.

Collagen is an essential protein that is vital for overall health and well-being. It provides support and structure to different body parts, ensuring their optimum functionality. The decline in collagen production is an inevitable part of aging, but several natural ways can help boost its levels. Maintaining a balanced diet, avoiding habits that damage collagen, and practicing regular exercise can help maintain healthy collagen levels. It's crucial to remember that relying solely on supplements may not necessarily boost collagen levels, so it's best to consult your healthcare provider before taking them. So, go ahead and adopt healthy habits to maintain healthy levels of this crucial protein. Your body will thank you for it!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6588)

Date: August 05, 2023 09:10 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Benefits of Vitamin D-3 In The Body!

As we live in modern times, most people spend their days indoors or in offices under artificial light. This fact can help explain why many individuals are deficient in vitamin D. This vitamin is crucial for bone health, immune function, and overall body wellness. If you're looking for a way to improve your vitamin D levels, Solaray Vitamin D-3 supplement can be a suitable solution. Lets dive into the benefits of this product and how it can help you maintain your health.

Improved Bone Health

Vitamin D is essential for the absorption of calcium. Calcium is a critical element that our bodies require for strong bones. Thus, deficiency in vitamin D can lead to Weak bones and fragile bone structures. Solaray brand Vitamin D-3 2000IU in Lemon flavor can supplement our bodies with enough vitamin D to enable sufficient calcium absorption and, in turn, strong and healthy bones & teeth.

Enhances Immune System

Our immune system is the first line of defense in protecting our bodies against diseases and infections. Vitamin D plays a pivotal role in the proper functioning of our immune system. Vitamin D boosts our white blood cells' activity, which helps combat infections and bacteria that may be detrimental to our system. Thus, supplementing with Solaray Vitamin D-3 2000IU can help improve your immune system's health and functionality.

Increases Dopamine/Serotonin Production

Dopamine/Serotonin are neurotransmitters that promotes positive thoughts, feelings of well-being, and happiness. Research has shown that maintaining optimal serotonin levels is essential for mental health and well-being. A Vitamin D-3 supplement can help increase serotonin production, leading to an improvement in mood and emotional regulation.

Boosts Mood and Mental Well-being

Vitamin D-3 plays a crucial role in mood regulation and warding off depression. It essentially works in the brain's mood centers and impacts the production of serotonin—a key hormone that stabilizes our mood, feelings of well-being, and happiness. Deficiency of Vitamin D-3 has often been linked with mood disorders, feeling of sadness, depression, and anxiety. By ensuring an adequate intake of Vitamin D-3, such as through supplements like Solaray Vitamin D-3 2000IU, you can maintain optimal serotonin levels, thereby improving your overall mood and promoting mental well-being. So, if you're feeling down more often than not, it might be a good idea to get your vitamin D levels checked and consider supplementation or more sunshine exposure.

Prevents Chronic Diseases

Deficiency in vitamin D has been linked to the development of chronic diseases such as multiple sclerosis, diabetes, and heart disease. Supplementing with Vitamin D-3 can reduce the risks of developing these diseases and improve your overall health.

Easy-to-take and Delicious Flavor

Solaray offers Vitamin D-3 2000IU in a Lemon flavor comes in a lozenge (under the tongue) form, making it easy and pleasant to consume. Hence, incorporating this supplement in your daily routine can be effortless and convenient.

In Summary: Supplementing with Solaray brand Vitamin D-3 can help boost your immune system, promote strong-bone-teeth development, enhance your mood, and prevent the development of chronic diseases. Additionally, the lemon flavor and lozenge form make it an enjoyable and easy-to-take supplement. Take care of your body and your health by incorporating a Vitamin D-3 supplement into your daily routine and feel the difference it can make in your life!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6583)

Date: November 05, 2022 10:41 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Importance of Vitamin B-12

Vitamin B-12 is an essential nutrient that is involved in energy production, brain and nerve health, DNA replication, red blood cell production, and myelin sheath formation. While you can get vitamin B-12 from eating certain foods, many people don't get enough of this important nutrient and may need to supplement with a vitamin B-12 supplement like Source Naturals Vitamin B-12 Sublingual 2000 mcg.

Vitamin B-12 is an important nutrient for many reasons. This water-soluble vitamin helps to convert carbohydrates into glucose, which is used for energy production in the body. It also helps to form red blood cells and helps with the absorption of iron. Iron is important for carrying oxygen in the blood. Vitamin B-12 is also necessary for proper DNA replication and for the formation of the myelin sheath, which is a layer of insulation around nerve cells.

Vitamin B-12 deficiencies are common, especially among older adults, vegetarians, and vegans. Symptoms of a vitamin B-12 deficiency include fatigue, Weakness, memory loss, depression, and nerve problems like numbness or tingling in the hands and feet. If you think you may be deficient in vitamin B-12, talk to your doctor about getting a blood test. A simple blood test can tell you if you are deficient in vitamin B-12 and whether or not you need to supplement with a vitamin B-12 supplement.

In Summary:

Vitamin B-12 is an essential nutrient that plays a role in energy production, brain and nerve function, DNA replication, red blood cell production, and myelin sheath formation.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6559)

Date: October 29, 2022 02:10 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Collagen: What is it and why should you care?

Collagen is the most abundant protein in our bodies, and it's one of the major building blocks of skin, hair, nails, bones, and joints. As we age, our bodies produce less and less collagen, which can lead to some unpleasant side effects. That's why it's important to get collagen in your diet, especially as you get older. Here's what you need to know about collagen and how to get more of it in your diet.

What is collagen?

Collagen is a protein that is produced by our bodies. It's made up of amino acids, which are the building blocks of proteins. There are 28 different types of collagen, but 90% of the collagen in our bodies is type I, II, or III. Collagen provides structure and support for our tissues and organs. It also helps with wound healing and plays a role in protecting our cells from damage.

Why do we need collagen?

As we age, our bodies produce less and less collagen. This can lead to wrinkles, joint pain, bone loss, muscle Weakness, and other unwanted side effects. Getting enough collagen in your diet can help keep your skin looking young and healthy, reduce joint pain, improve bone density, increase muscle mass, and more. That's why it's so important to make sure you're getting enough collagen as you age.

One good source of collagen is bone broth powder. Bone broth powder is made from the bones and connective tissues of animals. It's a rich source of protein and other nutrients like calcium and magnesium. Bone broth powder can be mixed into soups or smoothies, or used as a base for cooking grains or vegetables. You can also find collagen supplements at most health food stores. These supplements are usually made from fish or bovine sources.

In Summary:

Collagen is an important protein that our bodies need for proper function. As we age, our bodies produce less collagen, which can lead to some unpleasant side effects like wrinkles, joint pain, and muscle Weakness. Getting enough collagen in your diet is crucial for maintaining a healthy body as you age. Fortunately, there are plenty of ways to get more collagen in your diet. Bone broth powder is one good source of collagen; it's rich in protein and other nutrients like calcium and magnesium. You can also find collagen supplements at most health food stores. Making sure you're getting enough collagen in your diet will help you stay healthy well into your golden years!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6549)

Date: October 28, 2022 01:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: All You Need to Know About L-Carnitine

L-carnitine is a non-essential amino acid that has a variety of health benefits.* It is found naturally in red meat and other animal products, but the best way to ensure you're getting enough is through supplementation. NOW Foods offers a highly absorbable liquid form of L-carnitine that is vegetarian (non-animal sourced) and clinically tested for purity. Let's take a closer look at the benefits of L-carnitine and why you should consider adding it to your supplement regimen.

What are the benefits of L-carnitine?

As we age, our bodies become less efficient at producing carnitine, which can lead to fatigue, muscle Weakness, heart problems, and brain fog.* Supplementing with L-carnitine has been shown to improve these symptoms by facilitating the transfer of fatty acids into the mitochondria for energy production.* In addition, L-carnitine has also been shown to boost cognitive performance, increase exercise recovery times, and protect against age-related cognitive decline.*

Why choose NOW Foods L-Carnitine Liquid?

NOW Foods L-Carnitine Liquid is a pure, vegetarian (non-animal sourced), clinically tested product. It is also one of the most absorbable forms of carnitine on the market - meaning you'll get all of the benefits with less product. No matter your age or fitness level, adding NOW Foods L-Carnitine Liquid to your supplement regimen is a great way to support overall health and vitality.

In Summary:

L-carnitine is a non-essential amino acid with powerful health benefits that becomes more important as we age.* Supplementing with a pure, clinically tested product like NOW Foods L-Carnitine Liquid is an excellent way to ensure you're getting enough carnitine to support overall health and vitality.* Give it a try today!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6542)

Date: October 25, 2022 04:49 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Many Health Benefits of Copper Glycinate

You may not realize it, but copper is essential for many different bodily functions. This trace mineral is involved in energy production, iron metabolism, connective tissue syntheses, and neurotransmitter production. Copper is also critical for bone health, cardiovascular health, lipid metabolism, neurological health, skin health, and free radical protection. Keep reading to learn more about the many health benefits of copper.

Copper and Energy Production

One of the most important roles that copper plays in the body is in energy production. Copper is a key component of mitochondria, which are known as the "powerhouses of the cell." The mitochondria produce ATP (adenosine triphosphate), which is the energy currency of the cell. Therefore, without adequate copper levels, your cells would not be able to produce enough ATP for optimal function.

Copper and Iron Metabolism

Another important role of copper is in iron metabolism. Copper is necessary for the absorption and utilization of iron in the body. Iron is a key component of hemoglobin, which carries oxygen around in the blood. Therefore, without adequate copper levels, your body would not be able to properly utilize iron, leading to anemia or other problems.

Copper and Connective Tissue Synthesis

Copper is also necessary for the synthesis of collagen and elastin, two proteins that make up connective tissue. Connective tissue includes things like skin, tendons, ligaments, and cartilage. Therefore, copper is necessary for healthy skin as well as strong tendons and ligaments.

As you can see, copper plays many vital roles in the body. If you are deficient in copper, you may experience fatigue, anemia, Weak bones or connective tissue, problems with lipid metabolism or neurological function, or poor skin health. To ensure that you are getting enough copper in your diet, eat foods like liver, oysters, lobster, dark chocolate, avocados, almonds, mushrooms ,or leafy green vegetables. You can also take a copper supplement if needed.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6526)

Date: October 11, 2022 11:18 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Many Benefits of Graviola(Diabetes, Liver, Parasites)

Graviola, also known as soursop, is a small, green fruit that grows in tropical climates. The fruit, leaves, and seeds of graviola have been used for centuries in traditional medicine to treat a variety of conditions. Today, we know that graviola can help control diabetes and blood sugar problems, cleanse the liver, and remove parasites. These functions help in cases where underlying blood sugar imbalances and immune system Weakness are persistent problems. Also, numerous studies of Graviola have shown selective cytotoxicities against several lines of cancer cells. Let's take a closer look at some of the ways graviola can benefit your health.

Graviola and Diabetes

Graviola can be helpful in managing diabetes and blood sugar levels for two reasons. First, graviola helps to increase insulin sensitivity. Second, graviola leaf extract has hypoglycemic properties, which means it can help to lower blood sugar levels. A study published in the Journal of Ethnopharmacology found that rats with diabetes who were given graviola leaf extract had significantly lower blood sugar levels than rats who were not given the extract.

Graviola and the Liver

Graviola can also help to cleanse the liver and protect it from damage. The liver is responsible for filtering toxins out of the body, so it is important to keep it healthy. Graviola helps to keep the liver healthy by reducing inflammation and protecting it from oxidative damage. A study published in the International Journal of Molecular Sciences found that graviola was able to protect the liver from oxidative damage in rats with liver disease.

Graviola and Parasites

In addition to its other benefits, graviola can also help to eliminate parasites from the body. Parasites can cause a wide range of problems including fatigue, gastrointestinal issues, and weight loss. A study published in Phytotherapy Research found that graviola was effective at eliminating parasites in rats infected with the parasite Ascaris suum.

In Summary:

Graviola is a small fruit with a big impact on health. It can help to control diabetes, cleanse the liver, and remove parasites from the body. Additionally, studies have shown that graviola has anti-cancer properties. If you are looking for a natural way to improve your health, Graviola may be worth trying!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6499)

Date: October 03, 2022 03:04 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Collagen for Healthy Joints, Bones and Skin

Collagen is a protein that is found in abundance in mammals. It makes up about 30% of the body's protein and is known for its roles in bone, joint and skin health. Studies have shown that hydrolyzed collagen can help to support strong bones, healthy joints and smooth, hydrated skin.* Lets take a closer look at the benefits of collagen peptides from types 1 and 3 bovine collagen.

As we age, our bodies produce less collagen. This decrease in collagen production can lead to a number of age-related issues such as wrinkles, joint pain and Weak bones. Supplementing with collagen peptides can help to offset the decline in natural collagen production.* Collagen peptides are easily absorbed by the body and have been shown to promote joint health, bone density and skin elasticity.*

There are many different types of collagen, but types 1 and 3 bovine collagen are most commonly used for supplements. Type 1 collagen is particularly good for skin health, while type 3 collagen is best for joint health. Both types of collagen are found in our bones, tendons, ligaments and skin. Hydrolyzed collagen from types 1 and 3 bovine sources provides the most benefit for overall bone, joint and skin health.*

Collagen peptides from types 1 and 3 bovine sources are well-known for their roles in supporting bone, joint and skin health. Supplementing with hydrolyzed collagen can help to offset the decline in natural collagen production that occurs as we age.* Collagen peptides are easily absorbed by the body and have been shown to promote joint health, bone density and skin elasticity.* If you're looking for a supplement to support overall bone, joint and skin health, consider hydrolyzed collagen from types 1 and 3 bovine sources.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6480)

Date: September 21, 2022 11:25 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Benefits of NOW Calcium & Magnesium Citrate Powder with Vitamin D3

NOW Calcium & Magnesium Citrate Powder with Vitamin D3 is an optimal bone structure support formula designed by NOW's certified nutritionists.* It contains key nutrients that play essential roles in bone metabolism.* The citrate forms of calcium and magnesium are highly absorbable and support not only strong bones and teeth but muscle and nerve function as well.* Vitamin D3 is included to complement calcium and magnesium and its role in the maintenance of mineral homeostasis and bone structure.*

Why Calcium is Important for Your Bones

Most people are aware that calcium is important for strong bones, but many don’t know why. Calcium is a mineral that works together with phosphorus to build strong bones and teeth. When you don’t have enough calcium, your body will take it from your bones, which can lead to Weak bones or osteoporosis. Milk, cheese, and yogurt are good sources of calcium, but you can also get it from dark green leafy vegetables, tofu, almonds, and sardines. If you can’t get enough calcium from food alone, you may need to take a supplement.

The Importance of Magnesium

Magnesium is another mineral that’s critical for bones—in fact, it’s required for the proper absorption of calcium. Magnesium also helps regulate blood pressure, supports immunity, and aids in muscle contraction and relaxation. Good sources of magnesium include dark chocolate, bananas, avocados, almonds, and spinach.

Vitamin D3 for Healthy Bones

Vitamin D3 is a type of vitamin D that your body can more easily absorb. vitamin D helps your body absorb calcium and phosphorus (which help form strong bones), supports immunity, maintains healthy blood pressure levels, and aids in muscle contraction. You can get vitamin D from sunlight exposure (about 15 minutes a day), fatty fish such as tuna or salmon, beef liver or egg yolks. You can also take supplements if you need to.

In Summary:

To maintain strong bones throughout your lifetime, make sure to include NOW Calcium & Magnesium Citrate Powder with Vitamin D3 in your diet!* This optimal bone structure support formula not only contains calcium, magnesium, and vitamin D3—key nutrients that play essential roles in bone metabolism—but it also uses the absorbable citrate forms of calcium and magnesium so you can be sure your body is getting the most out of these minerals.* Supplementing with NOW Calcium & Magnesium Citrate Powder with Vitamin D3 can help support not only strong bones and teeth but also muscle function.*

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6458)

Date: September 14, 2022 04:03 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Consequences of Not Getting Enough Sleep

Most people know they should be getting around eight hours of sleep per night, but according to the National Sleep Foundation, between 50 and 70 million U.S. adults havea sleep disorder*. That means many of us are not getting the quality sleep we need on a nightly basis. But what does that mean for our health? Let’s take a look.

Short-Term Effects of Sleep Deprivation

There are many short-term effects of not getting enough sleep, including:

* Difficulty concentrating or making decisions * Increased forgetfulness * Moodiness or irritability * Slow reflexes * Increased anxiety * Decreased sex drive * Weight gain or weight loss * Heightened senses * Increased susceptibility to colds and flus

Long-Term Effects of Sleep Deprivation

The long-term effects of sleep deprivation are even more concerning. Some of the long-term effects of not getting enough sleep include:

* High blood pressure * Diabetes * Heart disease * Mood disorders such as depression or anxiety * Memory problems * Weakened immune system * Increased pain perception Conclusion: As you can see, there are many short-term and long-term effects of not getting enough sleep. If you think you might have a sleep disorder, talk to your doctor about treatment options. In the meantime, practice good sleep hygiene by avoiding caffeine before bedtime, establish a regular sleep schedule, and create a calming bedtime routine. Do your best to get seven to eight hours of quality sleep every night so you can wake up feeling refreshed and ready to take on the day!

Need more sleep try melatonin!

What is Melatonin?

Melatonin is a hormone that helps regulate our sleep-wake cycles. It's produced naturally by our bodies in response to darkness and starts to increase in the evening as we prepare for bed.

How Does Melatonin Work?

Many people take melatonin supplements in an effort to improve their sleep quality. And there is some evidence to suggest that it can be helpful. One small study found that melatonin supplements helped people fall asleep faster than placebo pills did. However, the effects were only temporary, lasting for just three days.

Another study looked at the effects of melatonin on people with insomnia due to jet lag. This research found that melatonin supplements shortened the time it took for participants to fall asleep by about an hour on average.

It's important to note that these studies looked at short-term usage of melatonin supplements. There's not much research available on the long-term effects of taking this supplement.

If you're struggling to get enough sleep, you might be wondering if supplements could help. One popular option is melatonin. But what is it, and does it really work? Melatonin is a hormone that helps regulate our sleep-wake cycles which is produced naturally by our bodies in response to darkness.. Many people take melatonin supplements in an effort to improve their sleep quality and there is some evidence to suggest that it can be helpful such as one small study found that melatonin supplements helped people fall asleep faster than placebo pills did.. however the effects were only temporary lasting three days or another study which looked at the effects of melatonin on people with insomnia due to jet lag and found that it shortened the time it took participants to fall asleep by an hour on average...

Give Melatonin a try and sleep better!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6451)

Date: September 09, 2022 04:24 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Stress, the body, and a possible solution.

We've all heard of stress, and we all know that it can have an effect on our bodies, but what exactly is stress? Stress is the body's response to any demand placed upon it. When we perceieve a threat, whether it's real or imagined, our body reacts accordingly. The autonomic nervous system kicks into gear, releasing a number of hormones, including adrenaline and cortisol. These hormones increase heart rate and blood pressure while also boosting energy levels. This "fight-or-flight" response is meant to help us deal with perceived danger, but when it's constantly activated, it can take a toll on our physical and mental health.

The Effects of Chronic Stress

Chronic stress can lead to a number of different health problems, both physical and mental. It can Weaken the immune system, making us more susceptible to illness. It can also cause headaches, stomach problems, insomnia, and anxiety. In extreme cases, it can even lead to heart disease or stroke.

Stress management is important for maintaining good health and preventing these problems from developing. There are a number of different ways to manage stress, including exercise, relaxation techniques such as meditation or yoga, spending time with supportive friends or family members, and seeking professional help if necessary.

While some amount of stress is inevitable in life, it's important to keep it under control to prevent it from having a negative impact on our health. If you find yourself struggling to manage your stress levels, don't hesitate to seek out professional help. In the meantime, there are plenty of self-care techniques that can be effective in managing stress such as exercise, relaxation techniques, and spending time with loved ones.

Is there a solution?

Everyone experiences stress from time to time, whether it's from work, school, or personal relationships. When left unchecked, stress can lead to serious health problems like anxiety and depression. Fortunately, there are ways to combat stress before it takes a toll on your health. One of the most effective ways is to take a B-complex supplement. B-vitamins are essential for maintaining a healthy nervous system, and they've been shown to help the body cope with stressful situations. In addition, B-vitamins help to regulate mood and energy levels, which can further help to reduce stress. If you're looking for a natural way to manage stress, a B-complex supplement may be just what you need.

Adding Vitamin C to your diet can help as well

Vitamin C is an essential nutrient that plays a role in many different body processes. It is known for its immune-boosting properties, but it can also help to reduce oxidative stress and improve overall stress levels in the body. Oxidative stress occurs when there is an imbalance between the production of reactive oxygen species and the body's ability to detoxify them. This can lead to cell damage and inflammation, which can contribute to the development of chronic diseases. However, vitamin C is a powerful antioxidant that helps to neutralize reactive oxygen species, protecting cells from damage. Additionally, vitamin C plays a role in the production of adrenal hormones, which helps to regulate stress levels in the body. As a result, adding vitamin C to your diet can help reduce oxidative stress and improve overall stress levels in the body.

No matter what life sends your way, try to stress out and take a quality B-vitamin and Vitamin C can help.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6435)

Date: August 02, 2022 05:39 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamins C and D: The Immune System Supplements You Need

It's that time of year again. The leaves are changing color, the days are getting shorter, and people are starting to get sick. If you're looking for a way to boost your immune system, you may want to consider taking vitamins C and D. These two essential nutrients have been shown to be beneficial for immune health, and can help keep you healthy during the cold and flu season. Lets discuss the benefits of Vitamins C and D for immunity, as well as how to get them into your diet.

What are Vitamins C and D, and what do they do for the immune system?

vitamins C and D are essential nutrients that play a vital role in supporting the immune system. Vitamin C is a powerful antioxidant that helps to protect cells from damage, while vitamin D helps to regulate the body's response to infection. Both vitamins are found in a variety of foods, including citrus fruits, leafy greens, eggs, and fatty fish. In addition, both vitamins can also be taken as supplements. While both vitamins are important for immune system health, vitamin C is particularly critical during times of heightened stress or illness, as it helps to boost the body's production of white blood cells. Vitamin D, on the other hand, is essential for maintaining a healthy balance of inflammation in the body. Without adequate levels of vitamin D, the body may become excessively reactive to foreign invaders, leading to chronic inflammation and a higher risk of infection. Together, vitamins C and D play an important role in keeping the immune system functioning properly.

Are there any side effects associated with taking too much of these vitamins?

Although you can get vitamins C and D through your diet, sometimes it's not enough to boost your immune system. The only way to ensure you're getting enough of these essential vitamins is to supplement your diet with pills or injections. Vitamin C is found in citrus fruits, tomatoes, potatoes, and leafy green vegetables. However, your body can't store vitamin C, so you need to consume it on a daily basis. Vitamin D is found in fatty fish, egg yolks, and fortified milk. However, most people don't get enough vitamin D from their diet and need to supplement it with pills or injections. Supplementing your diet with vitamins C and D is the only way to ensure you're getting enough of these essential nutrients to boost your immune system.

How can you make sure that you're getting the most out of your vitamins C and D supplements for immune health?

When it comes to vitamins C and D, there are a few things you can do to make sure you're getting the most out of them. First, vitamin C should be taken in divided doses throughout the day. This ensures that your body has a constant supply of the vitamin and can make use of it more efficiently. Second, vitamin D can be taken once per day. Finally, remember to take your vitamins with food. This ensures that your body gets the full benefits of the nutrients and doesn't waste any of them. By following these simple tips, you can help ensure that you're getting the most out of your vitamins C and D.

What are some other ways to boost your immune system during the cold and flu season?

While there are many products on the market that claim to boost your immune system, there is no magic pill that can protect you from colds and flu. However, there are a few simple steps you can take to reduce your chances of getting sick. First, make sure you're getting enough sleep. Sleep helps your body to repair and regenerate cells, which is essential for maintaining a strong immune system. Second, eat a healthy diet. Eating plenty of fruits and vegetables will give your body the nutrients it needs to fight off infection. Finally, try to reduce stress. Stress can Weaken your immune system, so it's important to find ways to relax and de-stress. Taking these simple steps will help you stay healthy during cold and flu season.

It's important to get enough vitamins C and D to boost your immune system. You can do this by supplementing your diet with pills, eating a healthy diet, and getting enough sleep. By following these simple tips, you can help ensure that you're getting the most out of your vitamins C and D supplements and keep your immune system functioning properly during cold and flu season.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6423)

Date: April 29, 2022 12:41 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Delta-8 THC Shows Promise in Combating Myocarditis

Heart disease is the leading cause of death in America, and myocarditis is one of the most common causes. Researchers are constantly looking for new ways to combat this deadly disease, and Delta-8 THC may be a promising treatment. A recent study found that Delta-8 was able to slow down heart rate and reduce inflammation in mice with myocarditis. While more research is needed, these findings suggest that Delta-8 could be a valuable tool in the fight against heart disease.

What is myocarditis and what are the symptoms?

Myocarditis is a term used to describe inflammation of the heart muscle. This can occur for a variety of reasons, including infection or injury, and it can cause a wide range of symptoms. Some of the most common signs of myocarditis include shortness of breath, chest pain, and chest tightness. Other possible symptoms include dizziness, lightheadedness, fatigue, nausea, and Weakness. If you experience any combination of these symptoms along with changes in your heart rate or blood pressure, it is important to seek immediate medical attention to determine whether you are suffering from myocarditis. Treatment will depend on the specific cause of your condition, but it typically involves anti-inflammatory medications and rest. Early diagnosis and treatment are essential for preventing the progression of the disease and reducing the risk of cardiovascular complications.

What causes myocarditis and how is it diagnosed?

Myocarditis is a condition characterized by inflammation and swelling of the heart muscle. This can lead to a number of symptoms, such as shortness of breath, chest pain, increased heart rate, and cough. There are many possible causes of myocarditis, including infections, autoimmune disorders, metabolic or nutritional disorders, or exposure to toxins or other irritants. In order to diagnose myocarditis properly, doctors will typically perform several different tests. These may include blood tests, scans of the heart using ultrasound or MRI technology, and electrocardiograms to assess heart activity. Ultimately, the treatment for myocarditis will depend on its underlying cause and the severity of symptoms. With proper care, however, most people can recover fully from this condition.

How is myocarditis treated and what are the potential complications?

Myocarditis is a condition that occurs when the heart muscle becomes inflamed. This can be caused by a viral infection, an autoimmune reaction, or other factors. Treatment for myocarditis generally involves addressing the underlying cause, if possible. For example, if the inflammation is due to a viral infection, antiviral medications may be prescribed. Corticosteroids may also be used to reduce inflammation. In some cases, heart surgery may be necessary to repair damage to the heart muscle. Complications of myocarditis can include heart failure and arrhythmias. With prompt and appropriate treatment, however, most people with myocarditis recover fully.

What is Delta-8 THC and how does it work?

Delta-8 THC is a chemical compound that is found in the Hemp plant. Unlike other forms of THC, which produce psychoactive effects by binding to cannabinoid receptors in the brain, Delta-8 simply activates these receptors without producing any noticeable effects on cognition or perception. While the precise mechanism of action for this compound remains somewhat unclear, scientists believe that Delta-8 works by interacting with specific neuroreceptors in the brain and body, thereby triggering a series of responses that ultimately lead to changes in mood or behavior. Furthermore, research suggests thatDelta-8 may also have antioxidant properties and may be effective at reducing inflammation in certain tissues. Overall, while more research is needed to fully understand the pharmacological effects of this compound, it seems clear that Delta-8 has great potential as a therapeutic agent and may hold benefits for patients suffering from certain mood disorders or neurological conditions.

Delta-8, inflammation and relaxation

Delta-8 is a cannabinoid that is found in hemp plants. This compound has a similar structure to Delta-9 THC, the main psychoactive compound in cannabis. However, Delta-8 is much less potent than Delta-9 and does not produce the same psychoactive effects. Instead, Delta-8 provides a more mild physical response that is associated with relaxation and relief from anxiety and pain. Research suggests that Delta-8 may also be effective in reducing inflammation. This anti-inflammatory effect may be due to the ability of Delta-8 to bind to CB2 receptors, which are found in high numbers in the immune system. As a result,Delta-8 may offer a unique combination of anti-inflammatory and relaxant effects.

What are the findings:

The results of recent studies suggest that delta-8, a type of cannabinoid found in cannabis plants, may play a role in reducing the symptoms of myocarditis. Myocarditis is a condition characterized by inflammation and damage to the heart muscle, which can lead to serious complications such as cardiac arrest if left untreated. Early research has shown that delta-8 may be able to help protect against this deterioration, as it was found to reduce levels of oxidative stress and inhibit pro-inflammatory signaling pathways. As more studies continue to explore the mechanisms underlying myocarditis, it is hoped that delta-8 will become an important tool for managing this deadly disease.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6398)

Date: September 04, 2020 11:05 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: No to Pain Pills and Yes to Safe and Effective Curcumin

Many people turn to over the counter (OTC) drugs when they experience pain, the common ones are non-steroidal anti-inflammatory drugs, better known as NSAIDS. The problem with NSAIDS these drugs reduce an enzyme associated with pain called COX-1 and COX-2. There are a lot of hidden dangers behind prescription and OTC pain killers. Some of the most common ones consumed are Ibuprofen an d Acetaminophen.

Ibuprofen: a popular OTC pain reliever can cause stomach pain, nausea, gastric bleeding, ulcers, confusion, hypertension, increased heart attack and stroke. Also, swelling, rapid weight gain, reduced urination, which is a sign of kidney dysfunction, kidney failure, fever, sore throat, headache, rash, bruising, tingling, numbness, muscle Weakness, neck stiffness, chills, light sensitivity, and seizures.

Acetaminophen: also known as Tylenol, is classified as an NSAID, but is also unsafe. The number one cause of liver failure in the United States is caused by acetaminophen next to alcohol consumption. If combined with alcohol, the damage to the liver is increased significantly. It also depletes glutathione, an important antioxidant needed by the liver to protect and detoxify the body. Over use of this OTC drug can cause nausea, vomiting, abdominal tenderness, and it can interfere with blood clotting, Weaken kidney function, and with severe over dose can cause death.

The alternative: Curcumin is a safe and effective pain reliever

Curcumin is a compound from Turmeric Root, unstandardized turmeric powder contains only two to three percent curcumin. It is important to get a standardized curcumin so that you can get a therapeutic response from consuming this herb. Not all curcumin is the same, look for a brand that blends turmeric essential oil with curcumin to enhance the absorption of the product because the product is hard to absorb.

Curcumin is one of the worlds best studied herbs, it works by reducing a COX-2 response to inflammation the same target as many prescription and OTC drugs that cause organ damage and side effects. Fortunately, Curcumin can target the same in a safe and natural way with no side effects. It can prevent a wide spectrum of inflammatory and oxidative damage, relieve chronic pain as effective and much more safely than drugs like NSAIDs.

Taking OTC or prescription pain relieving drugs are not a long term solution for pain. With the side effects associated with common pain relievers, one should only take them as a last resort and consider using a safer alternative that is as effective to relieving pain. Terry Naturally offers BCM-95 a patented curcumin that is blended with turmeric essential oils, BCM-95 has been the subject of many clinical studies demonstrating its effectiveness in relieving pain. We at VitaNet offer free shipping on any product in Terry’s brand. If you are struggling with pain, consider trying Terry Naturally to help relieve pain safely.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6363)

Date: May 14, 2019 04:11 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Zinc supplementation can benefit individuals with erectiledysfunction, reveals study

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6316)

Date: May 09, 2019 04:52 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 4 reasons you should eat more mushrooms

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6297)

Date: April 30, 2019 04:18 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cocoa isn’t just delicious – dies show it fights fatigue, too?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6228)

Date: April 24, 2019 01:42 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Understanding the many benefits of cannabis in cancer treatment

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6168)

Date: April 24, 2019 01:35 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cancer patients found to benefit from cannabis; scientific studyanalyzed outcomes of 2,970 cancer patients to confirm results

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6167)

Date: April 04, 2019 12:52 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Eat These Vitamin C-Rich Foods To Boost Your Immunity - NDTV

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6120)

Date: February 27, 2019 09:57 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 8 Health Hazards Caused by Lack of Vitamin D

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6057)

Date: February 15, 2019 05:00 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Curcumin Possesses ability to repair brain damage caused bystrokes

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6033)

Date: February 11, 2019 11:11 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: HIV-1 people can boost their immune system with Korean red ginseng

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6015)

Date: February 08, 2019 04:33 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 6 foods that are high in B vitamins - Sportskeeda

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6012)

Date: January 30, 2019 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Supplement with magnesium if you have diabetes it helps reduceinflammation in your body

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5994)

Date: January 04, 2019 03:13 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Long-term consumption of yerba mate found to strengthen yourdigestive system

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5931)

Date: January 04, 2019 08:12 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study: PQQ (pyrroloquinoline quinone) may prevent and even reverseAlzheimer's

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5928)

Date: November 13, 2018 08:51 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Help ward off infections and improve your immune system withoregano oil

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5830)

Date: October 21, 2018 12:52 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Natural remedies for osteoporosis: Several medicinal plants havebeen found to improve bone health without the side effects of medication

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5798)

Date: September 22, 2018 10:37 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Signs and symptoms of zinc deficiency - do you know what to lookfor?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5771)

Date: June 01, 2018 05:16 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Anthocyanin Benefits the Brain, Eyes & Immune System

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5623)

Date: May 29, 2018 05:16 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Try These 5 Tricks To Speed Up Your Metabolism Naturally

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5616)

Date: April 24, 2018 09:17 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Smoking marijuana found to have the same Weakening effect on the blood vessels as cigarettes

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5586)

Date: January 23, 2018 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A flavonoid found in guava and Osage orange has antioxidant properties that can reduce inflammation and improve “neurological deficits”

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5501)

Date: January 19, 2018 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: I Used These 4 Tricks To Cure Candida In A Week

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5496)

Date: January 15, 2018 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: If You Often Have Headaches, Low Energy, and Insomnia, Start Consuming These

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5489)

Date: January 07, 2018 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to beat stage 4 cancer: For one man, going vegan and quitting chemo saved his life

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5483)

Date: September 01, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is your Iron deficiency causing low energy?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5204)

Date: August 22, 2017 05:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Scientists: Children need microbes, not antibiotics, to develop immunity

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5158)

Date: August 04, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Foundations in Health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5083)

Date: July 23, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Brain cancer symptoms: Do YOU know the signs of John McCain's RARE aggressive type?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5024)

Date: July 21, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Help, and hope: Could cannabis possibly help fight cancer?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5012)

Date: June 26, 2017 05:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Miracle In A Glass: This Juice Fights Almost All Allergies!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4885)

Date: June 06, 2017 07:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 4 symptoms you should never ignore

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4778)

Date: June 04, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: With This Natural Syrup Look What Happen to your body - How to Treat Anemia

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4769)

Date: May 31, 2017 05:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: AMAZING. This Happens To Your Body WHEN YOU DRINK ALKALINE WATER!!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4735)

Date: May 27, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Kudzu Root: Beneficial Herb or Just a Hyped Plant Invader?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4707)

Date: April 25, 2017 11:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Never Ignore These Warning SIGNS OF VITAMIN B12 DEFICIENCY!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4475)

Date: April 19, 2017 08:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Magnesium 'could prevent broken bones'

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4432)

Date: April 13, 2017 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is pine tree bark the key to healthier, stronger teeth?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4403)

Date: April 08, 2017 06:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Eating These Foods Can Help You Get Your Daily Dose of Vitamin D - Pulmonary Fibrosis News

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4374)

Date: April 05, 2017 08:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Selenium Benefits: A Unique Trace Mineral That Provides Powerful Cancer Prevention

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4353)

Date: March 22, 2017 11:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Eating anti-inflammatory foods may reduce symptoms of rheumatoid arthritis

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4260)

Date: March 18, 2017 01:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Adaptogens: Why you need these super herbs in your diet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4206)

Date: March 16, 2017 11:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Watch ANOTHER Man with Severe Parkinson’s Take Cannabis Oil to Settle his Tremors

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4173)

Date: March 11, 2017 03:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamin D plays essential role in health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4100)

Date: March 08, 2017 05:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Make your bones stronger by following this diet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4083)

Date: February 27, 2017 10:19 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Home Remedies For Dry Cough That Will Give You Relief

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4033)

Date: February 20, 2017 10:19 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: IF YOU ARE LOSING YOUR HAIR AND YOU HAVE BRITTLE NAILS, This Is What You Need!!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3981)

Date: February 17, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: All you need to know about fatty liver

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3962)

Date: February 08, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Does depression boost the risk of cancer death?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3908)

Date: February 03, 2017 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Menopause: anti-inflammatory diet could help prevent fractures and boost bone health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3877)

Date: January 13, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Signs You Have a Vitamin Deficiency

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3776)

Date: January 01, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 4 signs that you have unhealthy bones

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3727)

Date: December 27, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Tired? Weak? You're not 'just getting old'; something is wrong

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3706)

Date: December 23, 2016 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Sky's Not Falling! Media Misreporting DEA on CBD “Illegality”

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3691)

Date: December 22, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 5 Sure Fire Ways to Know if You Have Hashimoto’s

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3685)

Date: December 14, 2016 10:22 PM
Author: Darrell Miller
Subject: How inflammation interferes with the formation of new bone material

One suffers from autoimmune inflammation when the immune system takes healthy cells to be foreign and fights them. This disease causes abnormal changes and growth in body organs; it can affect many or just one body tissue. Autoimmune inflammation usually runs in families. The main cause of the disease is not known, but theories usually rotate on factors like chemical irritants, drugs, environmental irritants and virus. Autoimmune inflammation interferes with the process of bone formation as the chemicals released by body cells increase blood flow resulting in warmth or swelling of the infected part. This swelling causes irritation of the joints and the bones cartilage wears down swelling the joint lining.

Bone remodeling highly depends on the balanced action between bone-resorbing and the osteoblast, in this process, an inflammatory process that would target the joint will affect the structure of the bone. This will result in impaired function of the bone and the destruction of bone tissue. OPC generally helps to lower the blood pressure, protect the brain, stop deep vein thrombosis, prevent oxidative and stop inflammation. The seed extract reduces anything damaging the joints and helps in immune regulation. They help stop the symptoms of collagen-induced arthritis. It helps in building of the backbone. It acts as antibacterial agents, preventing inflammable infections. Inflammation can also be prevented through exercises and stopping obesity. Modification of the diet and consumption of supplements will also help avoid inflammation.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3645)

Date: December 13, 2016 06:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Nourish your bones with vitamins - The Detroit News

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3631)

Date: December 10, 2016 04:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 4 Ways Food Can Fight Muscle Soreness

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3616)

Date: December 10, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to strengthen your bones

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3611)

Date: December 06, 2016 02:02 AM
Author: Darrell Miller
Subject: Is Glutathione The Fountain Of Youth?

Glutathione has created huge excitement in the medical world. Many experts believe that finally they have found the secret to eternal youth. Although Glutathione is naturally produced in our liver, but it gradually depletes as we age. Hence, it should be taken from external sources. Glutathione can be taken via pills. It can also be injected into our body through our veins. 

Glutathione, the Fountain of Youth

1. Detoxifying benefits: Everyday, lots of toxins enters your body from the environment or from the food which you eat. Whenever any toxin enters your system, the cells needs to work extremely hard in order to Weaken it. As a result, the antioxidants present in your body loses its energy quickly. However, Glutathione has enough energy to charge back the antioxidants. All the antioxidants in your body depends on Glutathione for the necessary supply of energy. 
2. Skin benefits: Glutathione is also very good for your skin. It makes your skin look more fresh and clear. Apart from that, it also gets rid of wrinkles and acnes. It can also get rid of serious skin diseases like melasma. A healthy skin will make you look much younger. 
3. Boosts the immune system: Glutathione is also very important for your immunity system. The cells which maintains your immunity system are called lymphocytes. They depend on Glutathione for the necessary supply of energy. Once they are equipped with Glutathione, they are able to fight against a wide variety of diseases. Apart from that, Glutathione also prevents the fat from getting oxidised. This helps your arteries to stay strong. If the arteries are clogged, then it can result in serious heart troubles. Glutathione also increases our stamina level, which allows us to perform more physical tasks.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3578)

Date: December 04, 2016 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Hormone therapy could help improve bone health in menopausal women

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3568)

Date: November 25, 2016 04:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Give your skeleton some love

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3509)

Date: November 23, 2016 08:06 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Diabetes and bone loss: Strategies to manage bone health with diabetes

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3492)

Date: November 17, 2016 02:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Science says you can worry yourself sick

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3460)