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NSAIDs vs. Curcumin: Which One Relieves Joint Pain Without Stopping Healing?   
Date:
September 14, 2026 11:22 AM
Comparative Analysis of NSAIDs versus Curcumin in Musculoskeletal Tissue RepairPrimary Biological Mechanisms and Pharmacological TargetsManaging soft tissue and joint injuries presents a persistent therapeutic challenge in musculoskeletal medicine. Acute inflammation triggers pain, localized swelling, and mechanical disability, which routinely drives patients toward pharmacological relief. For decades, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, celecoxib, and diclofenac have served as primary clinical interventions. While these synthetic agents effectively extinguish acute pain signals, expanding cellular and clinical research indicates that their biochemical mechanism interrupts the fundamental repair cascades required for long-term connective tissue healing. In contrast, curcumin - a natural polyphenolic compound derived from the rhizomes of Curcuma longa (turmeric) - exhibits a distinct, multi-targeted regulatory profile that calms hyperactive inflammation while protecting the structural components of cartilage and tendon tissue.The functional divergence between these two compounds becomes clear when considering an intuitive mechanical analogy. Tissue trauma resembles damage to a commercial building, where initial inflammation functions as the construction and demolition crew tasked with clearing rubble, stabilizing the foundation, and laying down fresh structural framing. NSAIDs function like abruptly cutting electrical power to the entire work site: the noisy machinery stops instantly and the immediate disturbance ceases, but the construction workers lose the power necessary to clean the debris and erect permanent walls. Conversely, curcumin operates as an experienced site manager: it silences unnecessary chaos and prevents site vandalism while ensuring that the skilled workers - specifically chondrocytes in cartilage and tenocytes in tendons - remain fully active, supplied, and capable of completing the restoration. At the cellular level, NSAIDs exert their effects through the catalytic inhibition of cyclooxygenase enzymes, categorized as constitutive cyclooxygenase-1 (COX-1) and inducible cyclooxygenase-2 (COX-2). Membrane phospholipids damaged during injury release arachidonic acid, which COX enzymes convert into pro-inflammatory lipid mediators known as prostanoids, most notably prostaglandin E2 (PGE2). Nonselective NSAIDs block both isoforms, while selective coxibs specifically target COX-2. By shutting off PGE2 production, NSAIDs rapidly elevate pain thresholds and blunt localized swelling. However, because PGE2 also functions as a vital signaling cue for cellular recruitment, angiogenesis, and cellular proliferation, this total enzymatic shutdown strips local repair cells of the baseline signals required to orchestrate tissue regeneration. Curcumin avoids this indiscriminate pathway paralysis by acting upstream on master transcriptional control switches rather than directly neutralizing isolated enzymes. Its primary therapeutic mechanism centers on the inhibition of Nuclear Factor-kappa B (NF-kB) and Activator Protein-1 (AP-1) signaling networks. Under acute stress or chronic inflammatory loads, the NF-kB protein complex is released from its cytoplasmic inhibitor, IkBa, and translocates directly into the cell nucleus, where it drives the transcription of catabolic cytokines such as interleukin-1 beta (IL-1ß), tumor necrosis factor-alpha (TNF-a), and interleukin-6 (IL-6). Curcumin blocks the phosphorylation and degradation of IkBa, effectively keeping NF-kB trapped in the cytoplasm. By preventing this nuclear entry, curcumin attenuates the expression of pro-inflammatory cytokines and downstream matrix-degrading enzymes while preserving baseline physiological functions. Furthermore, curcumin activates the nuclear factor erythroid 2-related factor 2 (Nrf2) and antioxidant response element (ARE) pathways, which upregulate endogenous cellular antioxidants to neutralize destructive reactive oxygen species (ROS) that induce cell death in injured joints.
The Mechanisms of NSAID-Induced Inhibition in Cartilage and Tendon RepairArticular cartilage and tendons are specialized, bradytrophic connective tissues characterized by relatively low basal metabolic rates and limited endogenous vascular supplies. These physical constraints make their cellular maintenance highly vulnerable to pharmaceutical disruptions. When synthetic compounds impair cell migration, survival, or extracellular matrix secretion, the intrinsic repair capacity of these structures is substantially degraded.Cartilage maintenance depends on chondrocytes, the sole cell type residing within articular joints, which are responsible for generating and maintaining the extracellular matrix of Type II collagen and water-binding proteoglycans such as aggrecan. Because adult articular cartilage lacks a direct vascular network, major defect repair relies heavily on the recruitment and chondrogenic differentiation of subchondral mesenchymal stem cells (MSCs) through endochondral ossification. Experimental evaluations demonstrate that systemic or intra-articular NSAID exposure halts this regenerative differentiation. Both nonselective NSAIDs and selective COX-2 inhibitors interfere with chondrocyte maturation and prevent successful tissue integration following cartilage transplantation or microfracture procedures. At the cellular level, common NSAIDs - including indomethacin, ketorolac, and diclofenac - induce cell cycle arrest in chondrocytes by blocking transition from the resting G0 phase to the proliferative G1. phase, substantially reducing viable cell numbers. Concurrently, NSAIDs downregulate Bone Morphogenetic Protein-2 (BMP-2), an essential anabolic signaling molecule that orchestrates matrix synthesis. Histological analyses in animal models reveal that NSAID administration causes a marked loss of extracellular proteoglycan content and widespread chondrocyte depletion, yielding elevated modified Mankin scores that signify advanced structural degeneration. In layman's terms, proteoglycans serve as water-absorbing structural sponges that grant cartilage its elastic shock absorption. When NSAIDs deplete these molecules, the joint surface dries out, becomes brittle, and rapidly wears down under routine mechanical friction. Tendon healing is similarly susceptible to disruption by NSAIDs. Tendons operate as high-tensile structural cables composed of longitudinally arranged Type I collagen fibers, maintained by specialized fibroblasts termed tenocytes and tenoblasts. Healing after acute rupture or chronic tear progresses through an initial inflammatory phase, followed by a proliferative phase of cell migration, and culminates in a lengthy remodeling phase of collagen alignment. In vitro and in vivo studies establish that NSAIDs directly suppress the migration and proliferative capacity of tenocytes during the critical early healing window. Without an adequate cellular workforce migrating into the wound bed, provisional collagen scaffolding cannot be synthesized effectively. The disruption is particularly pronounced at the enthesis, the specialized fibrocartilaginous junction where soft tendon inserts into rigid bone. Re-establishing this transition zone requires coordinated bone remodeling and chondrogenic differentiation, both of which are hindered by COX inhibition. In animal rotator cuff repair models, early administration of NSAIDs significantly delays collagen fiber organization and impairs mechanical integration at the insertion site, resulting in a measurable decline in load-to-failure strength and overall tendon toughness. Furthermore, while prolonged inflammation contributes to pathological degeneration, the transient synthesis of PGE2 during the initial hours following injury is essential for regulating localized microvascular flow and hyperemic nutrient delivery. By eliminating this early prostanoid pulse, NSAIDs starve the repair zone of oxygen and circulating factors precisely when the cellular metabolic demand is highest. Beyond direct biochemical cytotoxicity, systemic NSAIDs introduce a physical hazard known as analgesic arthropathy. In musculoskeletal biomechanics, pain functions as a protective feedback mechanism, forcing the patient to unload an injured joint or limb to prevent structural overload. By effectively blunting the pain reflex while simultaneously undermining the cellular synthesis of proteoglycans and collagen, NSAIDs create a deceptive state of perceived recovery. Patients prematurely resume unrestricted weight-bearing and strenuous activity, placing substantial, uncompensated mechanical forces onto compromised cartilage surfaces and unhealed tendon fibers. Over time, this recurring mechanical trauma accelerates joint space narrowing, promotes microfractures in the subchondral plate, and hastens functional joint breakdown. Chondroprotective and Tenogenic Mechanisms of CurcuminIn sharp contrast to the suppressive actions of synthetic COX inhibitors, curcumin exhibits a tissue-sparing, pro-regenerative biological profile. Rather than paralyzing cellular metabolism, curcumin modulates the microenvironment by suppressing destructive catabolic enzymes while supporting the baseline anabolic signals required for cartilage and tendon reconstruction.In articular cartilage, curcumin acts as a direct chondroprotective agent by dismantling the catabolic cascade induced by pro-inflammatory cytokines. When joint tissues are exposed to elevated IL-1ß and TNF-a, chondrocytes are provoked to synthesize matrix metalloproteinases - specifically collagenases such as MMP-1, MMP-3, and MMP-13 - along with aggrecanases like ADAMTS5. These enzymes function like enzymatic shears, systematically slicing through structural Type II collagen strands and degrading aggrecan cores. Curcumin suppresses the transcription and secretion of MMP-1, MMP-3, MMP-13, and ADAMTS5 by neutralizing NF-kB and AP-1 activation. Concurrently, it upregulates Cbp/p300 Interacting Transactivator with ED-rich tail 2 (CITED2), an essential transcriptional regulator that represses matrix metalloproteinases at the genomic level. In addition to halting extracellular degradation, curcumin protects chondrocytes from inflammatory apoptosis. Exposure to oxidative stress and inflammatory cytokines typically triggers programmed cell death by activating the intrinsic caspase cascade. Curcumin suppresses this apoptotic pathway by reducing the cleavage of executioner caspase-3, downregulating the pro-apoptotic factor Bax, and elevating anti-apoptotic Bcl-2 expression. Microscopic and histological analyses of osteoarthritic cartilage treated with curcumin consistently show robust Safranin O staining, intact surface regularity, preserved chondrocyte density, and significantly reduced Osteoarthritis Research Society International (OARSI) degradation scores. Within tendon biology, curcumin promotes active tissue regeneration (tenogenesis) rather than inert scar formation. In animal models of tendon rupture and surgical repair, curcumin guides tendon-derived stem and progenitor cells (TSPCs) toward mature tenocyte differentiation. This lineage-specific differentiation is orchestrated primarily through activation of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) and Wnt/ß-catenin signaling cascades. As stem cells commit to the tenogenic pathway, they significantly upregulate crucial structural and phenotypic markers, including epithelial cell adhesion molecule (EpCAM), tenomodulin, and the master tendon transcription factor Scleraxis. Through this guided differentiation, curcumin supports the preferential synthesis and organized deposition of high-tensile Type I collagen fibers, the primary architectural building blocks of healthy tendons. Injured tendons typically fill with disorganized, loose Type III collagen, which forms a structurally inferior, compliant scar. Curcumin supplementation promotes the progressive maturation from primitive Type III collagen to densely packed, parallel Type I collagen fibrils, restoring native tensile strength and mechanical breaking force. A major clinical challenge following tendon surgery is the development of peritendinous adhesions, in which excessive fibrotic scar tissue binds the healing tendon to its synovial sheath, restricting range of motion and joint gliding. Postoperative tendon repair involves a balance between extrinsic healing (in which exterior fibroblasts infiltrate the defect and deposit messy scar tissue) and intrinsic healing (in which tenocytes within the tendon substance reconstruct the matrix). Curcumin suppresses excessive peritendinous inflammation and extrinsic fibrosis while accelerating intrinsic tenocyte repair. Biomechanical testing confirms that local or systemic curcumin administration yields lower adhesion scores, increased gliding distances, and superior functional mobility without sacrificing structural load-bearing capacity. Comparative Clinical Efficacy and Systemic Safety ProfilesTranslating cellular findings into clinical practice requires weighing therapeutic outcomes against systemic safety profiles. While synthetic NSAIDs deliver potent, rapid analgesia during acute musculoskeletal pain events, their chronic administration is constrained by systemic toxicities across multiple organ systems.In randomized, active-controlled clinical trials of knee osteoarthritis, optimized curcumin preparations have demonstrated clinical pain reduction and functional recovery comparable to standard therapeutic doses of NSAIDs. In a randomized, open-label parallel-arm study evaluating 139 patients with symptomatic knee osteoarthritis, subjects received either 500 mg of a bio-enhanced curcumin extract three times daily or 50 mg of diclofenac sodium twice daily for 28 consecutive days. Patients treated with curcumin demonstrated comparable improvements in pain intensity on the Visual Analogue Scale (VAS) and functional scores on the Knee Injury and Osteoarthritis Outcome Score (KOOS) at days 14 and 28, showing no statistically significant difference in therapeutic efficacy compared to diclofenac. However, the systemic tolerability profiles between the treatments diverged markedly. Overall adverse events occurred in only 13% of the curcumin group compared to 38% of the diclofenac cohort. In the diclofenac arm, 28% of patients developed dyspeptic symptoms severe enough to require concurrent treatment with H2-receptor antagonists or proton pump inhibitors to prevent mucosal ulceration, whereas no patients in the curcumin cohort required gastroprotective intervention. Furthermore, the curcumin cohort experienced a significant reduction in flatulence and digestive discomfort, demonstrating beneficial gastric and intestinal cytoprotective effects. These safety observations are consistent across broader systematic reviews and meta-analyses. Nonsteroidal anti-inflammatory agents inherently compromise gastrointestinal integrity by systematically depleting cytoprotective prostaglandins, leaving the gastric epithelium vulnerable to acid erosion and hemorrhage. In addition, systemic inhibition of renal and vascular COX enzymes by NSAIDs reduces renal perfusion and disrupts the balance between prostacyclin and thromboxane, elevating the risk of fluid retention, hypertension, and adverse cardiovascular thrombotic events. Curcumin does not suppress these physiological prostanoid pathways, making it free from ulcerogenic, nephrotoxic, and cardiotoxic properties at therapeutic dosages.
A longstanding limitation of standard curcumin supplementation in clinical settings has been its low oral bioavailability. Native curcuminoids are highly lipophilic, poorly soluble in aqueous gastric fluids, and subject to rapid hepatic and intestinal phase II metabolism into inactive glucuronides and sulfates, leading to swift biliary and fecal excretion. Consequently, raw culinary turmeric powders struggle to achieve the therapeutic systemic circulating concentrations required to reach poorly vascularized joint and tendon compartments. Modern pharmacognosy has addressed this pharmacodynamic hurdle through advanced delivery formulations. Modern strategies - such as co-administration with the natural alkaloid piperine (which inhibits hepatic glucuronidation), micellar dispersions, phytosomal phospholipid complexes, and bio-enhanced submicron dispersions - elevate systemic blood bioavailability by ten- to thirty-fold compared to unformulated extracts. These modern delivery platforms ensure that therapeutic concentrations reach synovial fluid, subchondral bone, and fibrous tendon sheaths without requiring excessive oral dosing. Conclusions and Translational Clinical ImplicationsThe biological and clinical evidence reveals distinct physiological paths for NSAIDs and curcumin in orthopedic recovery. While NSAIDs remain powerful tools for the brief alleviation of acute, unmanageable pain, their ongoing administration during active tissue healing presents substantial biological compromises. Tendons and cartilage require a controlled, transient inflammatory cascade to signal cell recruitment, stimulate stem cell differentiation, and direct extracellular matrix synthesis. By completely shutting down cyclooxygenase enzymes and depleting local prostaglandins, NSAIDs disrupt this regenerative cascade. The resulting cellular consequences - including chondrocyte cell cycle arrest, proteoglycan loss, suppression of tenocyte migration, and weakened collagen tensile strength at the tendon-to-bone interface - demonstrate that pain relief from NSAIDs frequently comes at the cost of the structural integrity of healing connective tissues.In contrast, curcumin provides a tissue-preserving alternative that decouples pain and inflammation control from cellular suppression. Operating upstream at the level of NF-kB and AP-1 transcriptional activation, curcumin attenuates the expression of pro-inflammatory cytokines while leaving the physiological baseline of cellular metabolism intact. In cartilage, it actively represses the matrix-degrading enzymes MMP-1, MMP-3, MMP-13, and ADAMTS5, maintains water-binding proteoglycan content, and protects chondrocytes from inflammatory apoptosis. In damaged tendons, curcumin stimulates tenogenic differentiation of local stem cells via PI3K/Akt signaling, supports the proper maturation of dense Type I collagen fibers, and prevents restrictive peritendinous scar adhesions, preserving both joint mobility and mechanical breaking strength. From a translational perspective, these findings indicate that clinical protocols should reconsider relying on continuous NSAIDs as the default intervention for connective tissue injuries, post-surgical recovery, and chronic degenerative conditions. Where synthetic NSAIDs are deemed necessary, their use should be confined to short-term acute flare-ups to avoid interrupting early tissue remodeling. For long-term joint preservation, ongoing tendinopathy rehabilitation, and chronic osteoarthritis management, optimized bio-enhanced curcumin formulations deliver pain relief and functional restoration comparable to conventional pharmaceuticals, all while preserving the biological processes required for lasting musculoskeletal repair. References: NSAID therapy effects on healing of bone, tendon, and the enthesis The Detrimental Effects of Systemic Ibuprofen Delivery on Tendon Conservative management of symptomatic knee osteoarthritis - PMC Positives and negatives of nonsteroidal anti-inflammatory drugs in (PDF) Conservative management of symptomatic knee osteoarthritis Non-steroidal anti-inflammatory drugs influence cartilage healing Is Curcumine Useful in the Treatment and Prevention of ... - PMC - NIH Efficacy and mechanisms of curcumin in the treatment of osteoarthritis Biological actions of curcumin on articular chondrocytes - PubMed Curcumin slows osteoarthritis progression and relieves ... - PMC - NIH Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Anti-inflammatory management for tendon injuries - friends or foes? The mechanistic role of curcumin on matrix metalloproteinases in Therapeutic effects of turmeric or curcumin extract on pain and Curcumin inhibits chondrocyte apoptosis and inflammation in ... - PMC Analysis of the mechanism of curcumin against osteoarthritis using Synergistic enhancement of tendon-to-bone healing via anti ... - PMC A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis A randomized, pilot study to assess the efficacy and safety ... - PubMed Effectiveness of curcuminoids in the treatment of knee osteoarthritis THE EFFECTS OF TRADITIONAL STRENGTHENING EXERCISES Putting Some Muscle into Osteoarthritis | Annals of Internal Medicine Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Calebin A, a Compound of Turmeric, Down-Regulates Inflammation The Effect of Non-Steroidal Anti-Inflammatory Drugs on Tendon-to Chiropractor in Toronto, ON, Canada :: Head and Neck Pain Investigation of the association of long-term NSAID use with ... - PMC Curcumin Improves Functional Recovery of Ruptured Tendon by Chemically modified curcumin (CMC2.24) alleviates osteoarthritis Curcumin improves age-related and surgically induced osteoarthritis (PDF) Curcumin Improves Functional Recovery of Ruptured Tendon Investigation of the effects of umbilical cord-derived mesenchymal Effect of curcumin-loaded polycaprolactone scaffold on Achilles Controlled release of curcumin from curcumin-loaded nanomicelles Efficacy and safety of combination of curcuminoid complex ... - PMC The efficacy of Curcuma Longa L. extract as an adjuvant therapy in
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6653) The Ultimate Guide to Cellular Longevity: NAD+, Methylation, and Senolytics 
Date:
September 10, 2026 10:57 AM
Introduction: Understanding Cellular Aging and Energy DeclineBiological aging represents a progressive decline in cellular maintenance, structural repair, and energy generation. Over decades, tissues experience an attrition of functional reserves, compromised stress resilience, and persistent low-grade systemic inflammation. At the cellular scale, biological degeneration is driven by a failure to generate bioenergetic fuel, repair genetic code, and clear metabolic waste.Cellular aging is characterized by interconnected biological disruptions known as the hallmarks of aging. These encompass genomic instability, epigenetic alterations, mitochondrial decay, loss of proteostasis, and cellular senescence. Rather than operating as isolated occurrences, these phenomena establish a self-reinforcing degenerative cycle: declining cellular power generation impairs enzymatic genetic repair, promoting the accumulation of damaged cells that enter irreversible growth arrest and poison surrounding healthy tissues. Mitigating cellular aging requires examining how microscopic bioenergetic pathways deteriorate and evaluating how targeted nutritional and biochemical interventions can restore cellular homeostasis. The Role of Mitochondria and ATP ProductionEvery biological function - from muscular contraction to continuous DNA replication - depends on adenosine triphosphate (ATP), the primary biochemical energy currency of living systems. Cells produce the vast majority of this energy within mitochondria through oxidative phosphorylation. Within these specialized organelles, metabolic intermediates derived from dietary carbohydrates and lipids donate high-energy electrons to the electron transport chain. The flow of these electrons across protein complexes establishes an electrochemical proton gradient across the inner mitochondrial membrane, driving ATP synthase to manufacture ATP.A youthful cell functions like an efficient municipal power grid, dynamically matching energetic demands with immediate ATP output. However, as biological aging progresses, mitochondrial efficiency declines. The electron transport chain becomes structurally leaky, inadvertently shedding electrons that react with ambient molecular oxygen to produce reactive oxygen species (ROS). While regulated levels of ROS participate in vital intracellular signaling, chronic excess induces widespread oxidative stress. Mitochondria are exceptionally vulnerable to this oxidative burden because they carry their own circular genetic material, known as mitochondrial DNA (mtDNA). Unlike nuclear DNA, mtDNA lacks the protective shielding of histone proteins and possesses rudimentary repair systems. As a result, mtDNA sustains cumulative oxidative damage, encoding increasingly defective electron transport chain proteins. This dynamic generates a bioenergetic deficit: degraded mitochondria synthesize progressively less ATP while emitting greater volumes of damaging free radicals. Deprived of optimal ATP reserves, cells lack the energy necessary to drive vital enzymatic repair cascades, accelerating structural degeneration and functional exhaustion. How Cellular Senescence Accelerates the Aging ProcessWhen healthy cells confront critical physiological damage - such as severe telomere attrition, persistent DNA double-strand breaks, or oxidative stress - they activate protective cell cycle arrest pathways governed primarily by the p53/p21^CIP1 and p16^INK4a/Rb molecular checkpoints. This defensive shutdown, termed cellular senescence, permanently prevents the replication of potentially premalignant or mutated cells.Senescent cells, colloquially known as "zombie cells," enter a state of permanent growth arrest while actively resisting programmed cell death (apoptosis). Over time, these cells accumulate within adipose depots, skeletal muscle, the vascular endothelium, and major organs, largely because immune surveillance and clearance pathways simultaneously lose functional efficiency. The systemic danger of senescent cells stems from their secretome. Rather than remaining biologically inert, senescent cells develop a hyperactive secretory state termed the Senescence-Associated Secretory Phenotype (SASP). The SASP is a destructive mixture of pro-inflammatory cytokines, chemokines, extracellular matrix-degrading matrix metalloproteinases (MMPs), and reactive oxygen species. Through this toxic secretome, even a small burden of senescent cells can impair whole-tissue architecture. SASP factors degrade surrounding structural proteins, induce insulin resistance in neighboring metabolic cells, and biochemically force adjacent healthy cells into secondary senescence. This persistent paracrine signaling fuels chronic, sterile, low-grade systemic inflammation, termed "inflammaging," which accelerates systemic tissue degeneration and elevates susceptibility to degenerative age-related pathologies. Nicotinamide Riboside (NR) and the NAD+ Salvage PathwayThe Biochemistry of NAD+ Depletion Over TimeNicotinamide adenine dinucleotide (NAD+) is an indispensable coenzyme present in every living cell. NAD+ fulfills a dual biological mandate: it serves as a central redox cofactor that shuttles electrons between cellular metabolic reactions, and it functions as an obligatory consumable substrate for regulatory enzymes that preserve cellular viability. In its redox capacity, NAD+ accepts electrons to form NADH during glycolysis, the tricarboxylic acid (TCA) cycle, and fatty acid beta-oxidation, subsequently donating those electrons to Complex I of the respiratory chain to power ATP synthesis.
The primary enzymatic driver of age-related NAD+ destruction is CD38, a membrane-bound glycohydrolase expressed on immune cells that is upregulated in response to chronic SASP exposure. Concurrently, lifelong genotoxic damage causes persistent activation of Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that cleaves the glycosidic bonds of NAD+ to assemble branched poly(ADP-ribose) chains at DNA lesion sites. Because PARP-1 consumes NAD+ without directly recycling the molecule, chronic DNA damage depletes intracellular NAD+ pools, impairing bioenergetics and limiting sirtuin activity. How NR Efficiently Boosts Cellular NAD+ LevelsThe mammalian body maintains its NAD+ supply through three distinct biosynthetic routes: the de novo pathway from dietary L-tryptophan, the Preiss-Handler pathway from nicotinic acid (niacin), and the NAD+ Salvage Pathway. The de novo pathway requires substantial energy expenditure, consuming roughly sixty milligrams of dietary tryptophan to yield a single milligram of NAD+. The Preiss-Handler pathway, while effective, can induce cutaneous prostaglandin-mediated flushing at therapeutic intakes. Consequently, the salvage pathway serves as the primary mechanism for maintaining intracellular NAD+ pools.The salvage pathway recycles the breakdown product nicotinamide (NAM), which is released whenever NAD+-consuming enzymes execute their functions. Under normal conditions, cells convert free nicotinamide into nicotinamide mononucleotide (NMN) via the rate-limiting enzyme nicotinamide phosphoribosyltransferase (NAMPT), after which NMN adenylyltransferases (NMNAT1–3) complete the conversion into NAD+. However, NAMPT expression declines with advancing age, chronic inflammation, and metabolic stress, limiting the recycling capacity of the cell. Nicotinamide Riboside (NR) is a naturally occurring pyridine nucleoside that bypasses this enzymatic bottleneck. Upon cellular entry via equilibrative nucleoside transporters, NR is directly phosphorylated into NMN by nicotinamide riboside kinases (NRK1 and NRK2) using a single molecule of ATP. Because the NRK pathway remains intact and robust across the lifespan, NR provides an efficient alternative entry point into the NAD+ salvage cascade. Clinical evaluations in humans confirm the safety, bioavailability, and pharmacokinetics of oral NR supplementation. Randomized, double-blind, placebo-controlled trials reveal that oral NR chloride produces dose-dependent increases in steady-state whole blood NAD+ concentrations. Dosing regimens of 100 mg, 300 mg, and 1,000 mg daily elevate blood NAD+ levels by approximately 22%, 51%, and up to 142%, respectively, within two weeks of administration, maintaining these elevations throughout continuous use. High-resolution metabolomic analyses also demonstrate parallel elevations in nicotinic acid adenine dinucleotide (NAAD), establishing it as a reliable biomarker of active intracellular NAD+ synthesis without hepatic or systemic toxicity. Sirtuin Activation and DNA Repair MechanismsReplenishing intracellular NAD+ supports functions beyond mitochondrial ATP generation. NAD+ functions as an obligatory cofactor for sirtuins (SIRT1 through SIRT7), a family of class III histone and non-histone protein deacetylases that regulate stress resilience, metabolic homeostasis, and cell survival. Sirtuins couple the removal of acetyl groups from target lysine residues to the stoichiometric cleavage of NAD+, producing nicotinamide and O-acetyl-ADP-ribose. In states of NAD+ deficiency, sirtuin enzymes remain inactive regardless of cellular demand.In the nucleus, SIRT1 coordinates defense against cellular decline. When activated by restored NAD+ levels, SIRT1 deacetylates peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1a), the master transcriptional coactivator of mitochondrial biogenesis. This deacetylation stimulates mitochondrial replication and assembly, expanding functional respiratory capacity. Concurrently, SIRT1 deacetylates the p65 subunit of nuclear factor-kappa B (NF-kB), suppressing the transcription of pro-inflammatory cytokines. In the mitochondria, SIRT3 utilizes NAD+ to deacetylate metabolic enzymes and superoxide dismutase 2 (SOD2), enhancing the organelle's capacity to neutralize reactive oxygen species. At the same time, cellular NAD+ levels directly regulate genomic integrity through PARP-1. When genotoxic stress or oxidative damage induces single- or double-strand DNA breaks, PARP-1 binds to the damaged termini using its zinc-finger domains. Bound PARP-1 hydrolyzes NAD+ to synthesize extensive, negatively charged poly(ADP-ribose) polymers on itself and adjacent histones. This modification relaxes chromatin architecture and establishes an electrostatic scaffold that recruits base excision repair and homologous recombination complexes. Recent discoveries demonstrate close crosstalk between sirtuins and PARP-1 during DNA repair. PARP-1 recruits SIRT1 to double-strand breaks, where SIRT1 deacetylates the chromatin-remodeling ATPase BRG1 to displace nucleosomes and facilitate homologous recombination. However, because PARP-1 and SIRT1 draw from the same intracellular NAD+ pool, severe NAD+ depletion forces a biological compromise: PARP-1 consumes the scarce remaining cofactor to address DNA damage, leaving sirtuins deactivated. Restoring NAD+ via NR prevents this deficit, enabling concurrent genomic repair and sirtuin-mediated metabolic defense. Quercetin: A Powerful Senolytic and mTOR RegulatorClearing Senescent "Zombie" Cells from TissuesThe accumulation of senescent cells has driven interest in senolytics: molecules that selectively eliminate senescent cells while sparing healthy, non-senescent populations. Senolytic agents exploit a specific vulnerability in senescent cells. Because senescent cells produce cytotoxic, pro-inflammatory SASP factors that would normally induce their own death, they become dependent on upregulated Senescent Cell Anti-Apoptotic Pathways (SCAPs) to survive. The SCAP network involves anti-apoptotic proteins (such as BCL-2 and BCL-xL), the PI3K/Akt kinase cascade, and cyclin-dependent kinase inhibitors.Quercetin is a polyphenolic flavonoid found in capers, red onions, apples, and the flower buds of Sophora japonica. Beyond its classical antioxidant properties, quercetin functions as a senolytic compound that exerts multi-target inhibitory effects across the SCAP network. By inhibiting the upstream PI3K/Akt survival axis and downregulating anti-apoptotic defenses, quercetin disrupts the signaling that protects senescent cells from intrinsic apoptosis. Deprived of these survival signals, senescent cells undergo programmed cell death. Preclinical studies demonstrate that senolytic protocols utilizing quercetin - often combined with the tyrosine kinase inhibitor dasatinib - reduce senescent cell burden across multiple tissues. This targeted clearance lowers circulating SASP factors, attenuates tissue fibrosis, restores endothelial reactivity, and improves functional health span. By removing senescent cells, quercetin mitigates the primary driver of chronic, low-grade inflammaging. Modulating the mTOR Pathway for Optimal AutophagyThe mechanistic Target of Rapamycin (mTOR) is an evolutionarily conserved serine/threonine protein kinase that coordinates cellular metabolism by balancing anabolic growth with catabolic recycling. Operating within two multiprotein complexes - mTORC1 and mTORC2 - the mTOR pathway integrates signals from amino acids, growth factors, and intracellular energy levels. In nutrient-rich environments, mTORC1 promotes protein synthesis, lipogenesis, and cellular growth, while suppressing catabolic breakdown. Conversely, nutrient scarcity downregulates mTORC1, activating autophagy.Autophagy is an intracellular degradation system that packages damaged organelles, misfolded protein aggregates, and biological debris into double-membraned autophagosomes for lysosomal degradation and recycling. A specialized branch of this pathway, mitophagy, selectively targets and clears damaged mitochondria. In modern metabolic conditions characterized by continuous caloric intake, mTORC1 can remain persistently active. This persistent signaling suppresses autophagy, causing damaged organelles and toxic aggregates to accumulate within tissues. Quercetin functions as a natural modulator of mTOR signaling. By inhibiting upstream PI3K/Akt signaling and activating intracellular energy sensors, quercetin attenuates overactive mTORC1, mimicking the metabolic effects of caloric restriction. This down-regulation relieves inhibition on the ULK1 autophagy initiation complex, stimulating both general autophagy and mitophagy. As autophagy proceeds, cells clear protein aggregates and eliminate damaged mitochondria, supporting cellular longevity and proteostasis. Enhancing Absorption: Phytosomes and Dietary FatsDespite the biological activities of quercetin identified in experimental models, its clinical translation has historically been limited by poor oral bioavailability. Raw quercetin aglycone is a crystalline, hydrophobic polyphenol with poor solubility in water and gastrointestinal fluids. When ingested in unformulated powder forms, quercetin molecules aggregate in the gut lumen, resisting dissolution and passive absorption. Consequently, the vast majority of an unformulated dose passes into the colon unabsorbed, where it undergoes microbial degradation without reaching meaningful systemic concentrations.To address these pharmacokinetic limitations, advanced delivery systems such as phytosomes were engineered. A phytosome is a 100% food-grade molecular complex where individual polyphenolic molecules are bound to dietary phospholipids, typically sunflower-derived phosphatidylcholine. Unlike a classical liposome - which encapsulates water-soluble compounds inside an aqueous core enclosed by a lipid bilayer - a phytosome forms an amphiphilic complex at the molecular level. The polar head of the phosphatidylcholine molecule forms hydrogen bonds with the hydroxyl groups of the quercetin molecule, while its lipophilic fatty acid tails extend outward. This structural arrangement shields the polar regions of the flavonoid, creating a lipid-compatible complex that integrates smoothly into the intestinal mucosa.
The Importance of Methylation in Healthy AgingVitamin B-Complex and Choline as Essential Methyl DonorsMethylation is an essential biochemical process occurring billions of times each second across all human tissues. It involves the transfer of a single-carbon unit - a methyl group consisting of one carbon atom bound to three hydrogen atoms - (CH3) - from a donor molecule to diverse recipients, including DNA, RNA, structural proteins, neurotransmitters, and membrane phospholipids. This transfer of one-carbon units is coordinated by the methionine-homocysteine cycle, which sustains genetic stability, detoxification pathways, and cellular repair.At the center of this pathway sits S-adenosylmethionine (SAM), the universal methyl donor in human biology. When a methyltransferase enzyme transfers a methyl group from SAM to an acceptor molecule, SAM is converted into S-adenosylhomocysteine (SAH). SAH functions as a potent competitive inhibitor of intracellular methyltransferases. To maintain functional methylation, SAH is rapidly hydrolyzed into homocysteine, a sulfur-containing amino acid that must be remethylated or cleared through transsulfuration. Homocysteine clearance proceeds through two distinct remethylation pathways. The primary route operates across most tissues via the enzyme methionine synthase, which requires vitamin B12 in its active methylcobalamin form. Methionine synthase transfers a methyl group from 5-methyltetrahydrofolate (5-MTHF, the active form of folate) to homocysteine, regenerating methionine. The ongoing production of 5-MTHF depends on the enzyme methylenetetrahydrofolate reductase (MTHFR), which utilizes riboflavin (vitamin B2) as a cofactor. Alternatively, excess homocysteine can be routed into the transsulfuration pathway by vitamin B6 (as pyridoxal-5'-phosphate) to synthesize cystathionine, cysteine, and ultimately the antioxidant glutathione. A secondary remethylation pathway, active predominantly in hepatic and renal tissues, bypasses folate entirely. In this route, dietary choline is oxidized to betaine (trimethylglycine or TMG). The enzyme betaine-homocysteine S-methyltransferase (BHMT) then transfers a methyl group from betaine directly to homocysteine, yielding methionine and dimethylglycine. When dietary intake of active B-vitamins or choline is insufficient, or when genetic variations like MTHFR polymorphisms reduce pathway flux, the methylation cycle slows. Homocysteine accumulates in circulation, promoting vascular and neurological inflammation, while SAM reserves decline, restricting cellular methylation capacity. Understanding DNA Methylation and Epigenetic HealthEvery somatic cell in an organism carries an identical genetic code. Cellular differentiation and tissue-specific functions are governed by the epigenome: a regulatory layer of chemical modifications that dictates gene expression without altering underlying DNA sequences. DNA methylation represents the primary and most stable epigenetic modification. In this process, DNA methyltransferase (DNMT) enzymes utilize methyl groups donated by SAM to add a methyl tag to cytosine bases adjacent to guanine residues, forming 5-methylcytosine within CpG dinucleotide sites.Under physiological conditions, DNA methylation maintains genomic stability and coordinates transcription. Methylation of promoter regions condenses chromatin, repressing transposable elements and silencing genes inappropriate for a given cell type. Conversely, hypomethylated promoters maintain an open chromatin state, allowing transcription factors to bind and initiate gene expression. During biological aging, this epigenetic landscape undergoes progressive dysregulation, a phenomenon termed "epigenetic drift". Aging cells experience global hypomethylation alongside focal hypermethylation of specific gene promoters. Global loss of methyl tags destabilizes the genome, activating retrotransposons and pro-inflammatory pathways. Simultaneously, hypermethylation at targeted promoter sites silences critical tumor suppressor genes and DNA repair complexes. This systematic change in DNA methylation patterns is consistent across populations, allowing researchers to develop molecular "epigenetic clocks". Algorithms such as the Horvath clock, PhenoAge, and GrimAge quantify biological age by profiling the methylation status of specific CpG sites across the genome. These clocks assess whether individuals are aging faster or slower than their chronological years. Ensuring a steady supply of methyl donors and preventing unnecessary SAM depletion supports DNMT activity, maintaining epigenetic patterns and genomic stability. How the Methylation Cycle Impacts Energy and Cognitive FocusBeyond long-term epigenetic regulation, the methylation cycle directly modulates immediate biochemical processes that govern daily energy, neurotransmission, and cognitive focus. Compromised methylation capacity frequently manifests as cognitive slowing, executive fatigue, and reduced physical stamina.A major consumer of methyl reserves is the endogenous synthesis of creatine. Approximately 40% of all SAM-derived methyl groups in the human body are utilized by guanidinoacetate N-methyltransferase (GAMT) in the liver to synthesize creatine. Creatine then translocates to the brain and skeletal muscle, where it is phosphorylated into phosphocreatine. Phosphocreatine functions as a rapid energy buffer, donating a high-energy phosphate group to regenerate ADP into ATP in milliseconds during demanding physical or cognitive tasks. When methyl donor availability falls, endogenous creatine synthesis drops, depleting phosphocreatine reserves and increasing susceptibility to neuromuscular and cognitive fatigue. Methylation is equally central to central nervous system architecture. SAM provides methyl groups to convert phosphatidylethanolamine into phosphatidylcholine, the predominant phospholipid comprising neuronal cell membranes and the myelin sheaths that insulate axons. Intact myelin preserves rapid action potential conduction throughout the nervous system. Furthermore, free choline derived from this pathway is the direct precursor to acetylcholine, the neurotransmitter required for attention, working memory, and learning. The methylation cycle also governs monoamine neurotransmitter metabolism. SAM is required for the synthesis of adrenaline (epinephrine) from noradrenaline, while catechol-O-methyltransferase (COMT) relies on SAM to degrade dopamine and norepinephrine within the prefrontal cortex. Sluggish methylation disrupts this balance, contributing to cognitive fatigue, mood variability, and impaired mental performance. Building a Comprehensive Longevity ProtocolSynergizing NR, Quercetin, and Methylated B-VitaminsLongevity supplementation often falters when single molecules are administered in isolation, ignoring interconnected metabolic pathways. Designing an effective cellular longevity protocol requires combining complementary mechanisms that reinforce one another while preventing secondary metabolic deficits. The combination of Nicotinamide Riboside, Quercetin Phytosome, and Methylated B-Vitamins illustrates this multi-target synergy.This synergy is grounded in the direct biochemical intersection between the NAD+ salvage pathway and the methylation cycle. When high-dose NR is supplemented to boost systemic NAD+, sirtuins and PARP enzymes consume the newly synthesized cofactor, generating substantial quantities of free nicotinamide (NAM). This intracellular nicotinamide faces two primary metabolic fates: it can be recycled back into NAD+ through the NAMPT-dependent salvage loop, or it can be cleared via methylation. When the influx of nicotinamide exceeds salvage recycling capacity, the excess is cleared to avoid feedback inhibition of sirtuin enzymes. To accomplish this, the enzyme nicotinamide N-methyltransferase (NNMT) transfers a methyl group from SAM directly onto nicotinamide, forming 1-methylnicotinamide (1-MNA/MNAM), which is subsequently excreted in urine. Prolonged, high-dose precursor administration without nutritional methyl support can elevate NNMT flux, depleting intracellular SAM reserves. As methyl groups are consumed clearing nicotinamide, the cellular SAM-to-SAH ratio falls, which can elevate circulating homocysteine and reduce methyl availability for DNA methylation and neurotransmitter synthesis. Co-administering a fully methylated B-complex alongside choline or betaine addresses this potential bottleneck. Providing active methyl donors (such as 5-MTHF, methylcobalamin, and betaine) maintains the one-carbon donor pool. Even during increased NNMT activity, SAM pools remain stable, protecting DNA methylation fidelity and maintaining homocysteine within safe parameters. Quercetin reinforces this protocol through complementary mechanisms. By clearing senescent cells and reducing SASP-mediated inflammation, quercetin downregulates CD38, the primary enzyme responsible for age-related NAD+ degradation. Suppressing CD38 prevents unnecessary breakdown of newly synthesized NAD+, enhancing the efficiency of NR supplementation. Furthermore, while NR provides the NAD+ necessary to activate SIRT1-driven mitochondrial biogenesis, quercetin concurrently modulates mTORC1 to stimulate autophagy. This coordinated action ensures that newly generated mitochondria operate in an environment cleared of proteotoxic cellular debris. The Crucial Role of Magnesium Glycinate and Zinc in Cellular FunctionLongevity protocols require essential mineral cofactors to function efficiently. Without adequate divalent minerals acting as enzymatic cofactors and structural stabilizers, metabolic longevity pathways cannot operate at full capacity. Among these, magnesium and zinc are required for cellular repair, genomic stability, and energy production.Magnesium serves as an obligatory cofactor in over 300 enzymatic reactions, primarily through its interaction with ATP. In biological systems, ATP exists predominantly as a chelate with a divalent magnesium ion, forming biologically active Mg2+ -ATP. Every enzymatic reaction that synthesizes, transfers, or consumes cellular energy - including the enzymes of the NAD+ salvage pathway (NRK and NMNAT) and DNA polymerases - strictly requires Mg2+ -ATP as its substrate. Magnesium deficiency impairs these phosphorylation reactions, reducing the cellular utilization of NAD+ precursors. Additionally, magnesium is an essential cofactor for the enzymes that activate dietary B-vitamins into their active forms. Supplying magnesium as magnesium glycinate provides high gastrointestinal bioavailability, minimal laxative effect, and yields glycine to support inhibitory neurotransmission and restful sleep. Zinc serves as a vital structural component for more than 3,000 human transcription factors and enzymatic proteins. Its most prominent structural role in longevity occurs within zinc-finger motifs. These are specialized protein conformations stabilized by a zinc ion coordinated to cysteine and histidine residues. The DNA damage sensor PARP-1 utilizes three zinc-finger domains to identify, track, and physically bind to single- and double-strand DNA breaks. Without adequate intracellular zinc, PARP-1 cannot properly assemble or dock onto damaged chromosomes, impairing DNA repair and increasing genomic instability. Zinc is also an obligatory structural component of copper/zinc superoxide dismutase (Cu/Zn-SOD or SOD1), the primary cytosolic antioxidant enzyme that dismutates superoxide radicals into hydrogen peroxide, protecting mitochondrial membranes and nuclear DNA from premature senescence. Integrating Prebiotics (like Acacia and Inulin) for Gut-Derived Longevity MarkersA comprehensive cellular longevity framework must extend beyond somatic tissues to encompass the gut microbiome. The intestinal microbiome functions as a central regulator of systemic inflammatory tone, immune development, and metabolic signaling. Age-associated dysbiosis - characterized by the loss of beneficial commensals and an overgrowth of pathobionts - frequently leads to breakdown of the intestinal barrier.The gut epithelium consists of a single-cell monolayer sealed by tight junction proteins, including zonula occludens-1 (ZO-1), occludin, and claudins. When this physical barrier is disrupted by poor dietary fiber intake or dysbiosis, gut permeability increases. This allows lipopolysaccharide (LPS), a component of the outer membrane of Gram-negative bacteria, to enter the portal and systemic circulation. The resulting "metabolic endotoxemia" activates Toll-like receptor 4 (TLR4) on immune cells, inducing NF-kB and systemic pro-inflammatory cytokine production. This persistent gut-derived inflammation exacerbates the SASP, accelerates tissue senescence, upregulates CD38, and drains systemic NAD+ reserves.
These short-chain fatty acids, particularly butyrate, exert direct protective effects on systemic longevity. Butyrate provides the primary metabolic fuel for colonic epithelial cells, supplying more than 70% of their baseline energy needs and supporting mitochondrial function within colonocytes. Furthermore, SCFAs upregulate the expression of epithelial tight junction proteins (ZO-1, occludin, and claudin-1), restoring intestinal barrier integrity and preventing the translocation of inflammatory LPS into systemic circulation. Systemically absorbed butyrate also functions as an endogenous histone deacetylase (HDAC) inhibitor, suppressing pro-inflammatory gene expression and supporting regulatory T cell (T_reg) development. Reducing metabolic endotoxemia dampens systemic inflammation, protecting vascular function and preventing premature NAD+ depletion. Conclusion: The Integrated Cellular Longevity MatrixCellular longevity is achieved not by addressing isolated biomarkers in isolation, but by systematically supporting interconnected biological pathways. As bioenergetic capacity declines, cellular senescence accelerates, epigenetic patterns degrade, and gut barrier integrity weakens. A comprehensive approach addresses these biological vulnerabilities simultaneously.
Quercetin Phytosome clears senescent cells and modulates mTORC1, stimulating autophagy while dampening the inflammatory SASP cascade that accelerates CD38-mediated NAD+ destruction. Methylated B-vitamins, active folate, and choline replenish SAM reserves, balancing the methyl requirements of NNMT-mediated nicotinamide clearance, preserving epigenetic DNA methylation, and maintaining neurotransmitter production. Magnesium glycinate and zinc provide the structural and catalytic foundation required for ATP utilization, B-vitamin activation, and PARP-1 zinc-finger DNA repair docking. Finally, prebiotic fibers generate short-chain fatty acids like butyrate, reinforcing the intestinal barrier and preventing metabolic endotoxemia from fueling systemic inflammation. By coordinating energy replenishment, cellular waste clearance, epigenetic maintenance, and the suppression of systemic inflammation, this unified approach directly addresses the underlying drivers of cellular aging to support long-term physiological vitality.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6650) Can Inulin and Acacia Fiber, Both a prebiotic, cause friendly bacteria to produce short-chain fatty acids like Berberine helps promote the growth of beneficial Bacteria?
Date:
November 15, 2025 11:00 AM
Yes, absolutely! Both inulin and acacia fiber are classic examples of prebiotic soluble fibers, and their primary mechanism is to feed beneficial gut bacteria, which in turn produce short-chain fatty acids (SCFAs), including butyrate. Here’s a breakdown of how they compare to the berberine mechanism you mentioned. Prebiotic Fibers (Inulin & Acacia)This is a direct fermentation process.
BerberineBerberine's route to creating SCFAs is more indirect.As you noted, berberine isn't a fiber that bacteria ferment. Instead, it acts as a microbiome modulator:
Key TakeawayYou are right on track. While berberine helps manage the bacterial "team" to favor SCFA production, inulin and acacia fiber are the actual "food" or "fuel" that the team uses to create those SCFAs.Both pathways can lead to the same beneficial outcome - more of your body's own butyrate and other SCFAs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6627) Allercetin: Your Natural Defense Against Allergies and Sinus Issues
Date:
June 06, 2024 05:20 PM
Allergies and sinus issues can be a constant thorn in the side for many individuals. Everyday activities can feel like an uphill battle when you're plagued by congestion, sneezing, and itchy eyes. But what if there was a natural remedy that could provide relief across multiple body systems? Introducing Allercetin™ Allergy & Sinus, a Bio-Aligned Formula designed to tackle the root causes of your allergy symptoms.
Allercetin™ is not your average allergy treatment. This innovative product leverages natural homeopathic remedies to address the complex web of systems involved in allergic reactions. Unlike many over-the-counter medications that offer temporary relief, Allercetin™ provides a comprehensive approach, targeting the respiratory system, sinuses, mucous membranes, and more.
The key to Allercetin™'s effectiveness lies in its Bio-Aligned Formula. This advanced blend of natural ingredients is designed to support multiple body systems that are often affected by hay fever and other allergic conditions.
Breathing becomes a chore when your respiratory system is compromised by allergens. Allercetin™ contains ingredients that help to open up the airways, making it easier to breathe. This can be particularly beneficial during high pollen seasons when respiratory issues are at their peak.
Your sinuses play a crucial role in trapping allergens and preventing them from entering your respiratory system. However, when they become inflamed, they can cause severe discomfort. Allercetin™ supports the health of your sinuses, promoting natural drainage and reducing inflammation.
Mucous membranes are the body's first line of defense against airborne irritants. Allercetin™ helps to maintain the integrity of these membranes, ensuring they function optimally. This reduces the likelihood of allergens causing significant irritation and discomfort.
Histamines are chemicals in the body that play a central role in allergic reactions. When released in large amounts, they can cause symptoms like itching, swelling, and redness. Allercetin™ works to inhibit the release of histamines, thus reducing the severity of allergic reactions.
A hyperactive immune system can exacerbate allergy symptoms. Allercetin™ includes ingredients that help to desensitize the immune system, making it less reactive to allergens. This not only alleviates current symptoms but can also reduce the likelihood of future allergic reactions.
When your body is fighting allergies, it can drain your energy levels significantly. Allercetin™ supports cellular energy production, ensuring you have the stamina to go about your daily activities with ease.
Using Allercetin™ is simple and convenient. Take the recommended dosage as indicated on the packaging, preferably at the onset of symptoms. Consistency is key to experiencing the full benefits of this natural remedy.
Multiple factors set Allercetin™ apart from other allergy treatments on the market. Here are some reasons why you should consider making it a staple in your wellness routine:
Don't just take our word for it; listen to what our satisfied customers have to say:
Rigorous scientific research guided the development of Allercetin™. We selected each ingredient based on its ability to alleviate symptoms and support overall well-being. This guarantees you receive a product supported by both traditional wisdom and modern science.
Living with allergies and sinus issues doesn't have to be an ordeal. With Allercetin™ Allergy & Sinus, you can take a proactive approach to manage your symptoms naturally and effectively. Why settle for temporary relief when you can address the root causes of your discomfort? Experience the transformative power of Allercetin™ for yourself. Don't let allergies hold you back any longer. Visit our website today to purchase Allercetin™ Allergy & Sinus and reclaim your life from the shackles of allergies. Take the first step towards a healthier, more comfortable life—order now!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6613)
Date:
June 05, 2024 03:40 PM
In the world of health-conscious eating, coconut sugar has been gaining traction as a natural sweetener that boasts several benefits over traditional table sugar. Derived from the sap of coconut palm tree flowers, coconut sugar offers a unique flavor and versatile uses in a variety of culinary applications. This article delves into the numerous ways coconut sugar can be utilized in the kitchen, its glycemic index, and its nutritional profile, shedding light on why this sweetener has captured the hearts of many health enthusiasts.
One of the most popular ways to incorporate coconut sugar into your diet is through baking. Coconut sugar can be used as a one-to-one replacement for white or brown sugar in recipes, making it an easy swap for those looking to reduce their intake of refined sugars. Its caramel-like flavor enhances the taste of cookies, cakes, muffins, and other baked goods. For example, coconut sugar can add depth to chocolate chip cookies or provide a rich, molasses-like sweetness to gingerbread.
Coconut sugar can also be a delightful addition to both hot and cold beverages. It easily dissolves in liquids, making it a great sweetener for coffee, tea, smoothies, and even cocktails. For instance, adding a spoonful of coconut sugar to your morning coffee or afternoon chai tea can give your drink a subtle, tropical sweetness without the overpowering taste that sometimes accompanies artificial sweeteners.
In the realm of savory dishes, coconut sugar works exceptionally well in marinades, sauces, and dressings. Its ability to balance flavors makes it a staple in many Asian cuisines, particularly in Thai cooking. Use it to create a luscious teriyaki sauce or add it to a spicy barbecue marinade. Coconut sugar’s mild sweetness can complement and enhance the umami elements of soy sauce, ginger, and garlic, resulting in a harmonious blend of flavors.
Don’t overlook coconut sugar as a topping for breakfast or snacks. Sprinkle it over oatmeal, yogurt, or fresh fruit for a burst of flavor and a touch of sweetness. You can also use coconut sugar in homemade granola or energy bars. Its granular texture adds a pleasant crunch, and its rich taste pairs well with nuts, seeds, and dried fruits.
One of the significant advantages of coconut sugar is its lower glycemic index (GI) compared to regular table sugar. The glycemic index is a measure of how quickly a food raises blood sugar levels after consumption. Foods with a high GI can cause rapid spikes and crashes in blood sugar levels, which can be particularly problematic for individuals with diabetes or those managing their weight. Coconut sugar has a GI of approximately 35, which is considerably lower than the GI of table sugar, which hovers around 60-65. This lower GI means that coconut sugar causes a slower, more gradual rise in blood sugar levels. As a result, it can help maintain more stable energy levels throughout the day and prevent the sudden energy crashes that often follow high-sugar snacks or meals.
Aside from its lower glycemic index, coconut sugar also offers a more nutrient-dense alternative to refined sugars. While it is still a type of sugar and should be consumed in moderation, coconut sugar contains trace amounts of vitamins and minerals that can contribute to overall health.
Coconut sugar retains some of the nutrients found in the coconut palm sap. These include small amounts of iron, zinc, calcium, and potassium, all of which play crucial roles in maintaining bodily functions. For example, iron is essential for oxygen transport in the blood, while calcium supports bone health.
Coconut sugar also contains antioxidants, which help combat oxidative stress and reduce the risk of chronic diseases. Antioxidants can neutralize free radicals, unstable molecules that can damage cells and contribute to aging and diseases like cancer and heart disease.
Another noteworthy component of coconut sugar is inulin, a type of dietary fiber. Inulin acts as a prebiotic, feeding the beneficial bacteria in the gut and promoting a healthy digestive system. Its presence in coconut sugar can further contribute to its lower glycemic index by slowing down glucose absorption.
When purchasing coconut sugar, it’s essential to select high-quality brands that don’t mix the sugar with other sweetening agents like cane sugar. Always check the label to ensure you’re buying 100% pure coconut sugar.
Store coconut sugar in an airtight container in a cool, dry place to maintain its texture and flavor. It’s important to keep it away from moisture, as this can cause clumping and affect its usability.
Coconut sugar presents a versatile and nutritious alternative to traditional sweeteners, offering a wide range of culinary uses while providing a lower glycemic index and additional vitamins and minerals. Whether you’re baking your favorite dessert, sweetening your morning coffee, or enhancing a savory dish, coconut sugar can be a valuable addition to your pantry. Its unique flavor and health benefits make it an excellent choice for those looking to enjoy sweetness in a more wholesome form. By understanding and embracing the versatility of coconut sugar, you can make more informed and health-conscious decisions in your culinary endeavors.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6612)
Date:
June 04, 2024 04:57 PM
In recent years, agave nectar has gained popularity as a natural sweetener, touted for its unique taste and potential health benefits. But what exactly is agave nectar, and how does it stack up against traditional sugar and other sweeteners? In this comprehensive guide, we will delve into the uses and nutritional benefits of agave nectar, comparing it to traditional sugar and other sweeteners to help you make an informed decision.
Agave nectar, also known as agave syrup, is a sweetener derived from the sap of the agave plant. The agave plant is native to Mexico and has been used for centuries in traditional medicine and as a sweetener. The sap is extracted from the core of the agave plant, then filtered and heated at low temperatures to break down the complex carbohydrates into simple sugars. The result is a sweet, viscous liquid with a taste similar to honey, but with a thinner consistency.
Agave nectar is primarily composed of fructose, a simple sugar found in many fruits. Unlike traditional sugar (sucrose), which is made up of equal parts glucose and fructose, agave nectar usually contains about 70-90% fructose and 10-30% glucose. Here is a quick look at the nutritional content of one tablespoon (21 grams) of agave nectar:
Use agave nectar in various ways to add versatility to your kitchen. Here are some common uses:
Both agave nectar and traditional sugar contain similar amounts of calories per serving, but agave nectar is sweeter than sugar, which means you can use less of it to achieve the same level of sweetness. This can result in a lower overall caloric intake when using agave nectar as a sugar substitute.
One of the key differences between agave nectar and traditional sugar is their glycemic index (GI). The glycemic index measures how quickly a food raises blood sugar levels. Foods with a high GI cause a rapid spike in blood sugar, while those with a low GI release sugar more slowly and steadily. Agave nectar has a low glycemic index, typically between 13 and 30, which is significantly lower than that of traditional sugar (sucrose), which has a GI of around 65. This makes agave nectar a more suitable option for those trying to manage their blood sugar levels.
While agave nectar's high fructose content may contribute to its low glycemic index, it also raises some concerns. Consuming high fructose intake in large amounts has been linked to obesity, fatty liver disease, and insulin resistance. However, when used in moderation, agave nectar can be a healthier alternative to traditional sugar and high-fructose corn syrup.
Honey, often compared to agave nectar, provides a natural sweetener option with similar caloric content, allowing interchangeability in recipes. This sweetener has a higher glycemic index than agave nectar, meaning it can cause a quicker spike in blood sugar levels. However, honey also contains antioxidants, vitamins, and minerals, which can provide additional health benefits.
Maple syrup, like agave nectar, is a natural sweetener with a lower glycemic index than sugar. It also contains some beneficial nutrients, such as manganese and zinc. However, agave nectar is sweeter than maple syrup, so you may need to use less of it to achieve the desired sweetness.
Stevia, derived from the leaves of the Stevia rebaudiana plant, is a zero-calorie sweetener. It does not affect blood sugar levels and requires only a small amount due to its sweeter taste compared to agave nectar. If you want a super sweet brand of stevia, try Kal brand stevia, it has no after taste and contains over 1800 servings at a reasonable price. While stevia is a good option for those looking to reduce their caloric intake and manage blood sugar levels, some people find its aftertaste less appealing than that of agave nectar.
As mentioned earlier, agave nectar has a lower glycemic index than traditional sugar, making it a potentially better choice for those managing diabetes or trying to maintain stable blood sugar levels.
Agave nectar contains some antioxidants, which can help neutralize harmful free radicals in the body. While the antioxidant content is not as high as that found in honey or some fruits, it still provides some benefit.
Fructans, a type of carbohydrate found in agave, can act as prebiotics, promoting the growth of beneficial bacteria in the gut. This can contribute to better digestive health and overall well-being.
While agave nectar offers several advantages over traditional sugar and some other sweeteners, it is essential to use it in moderation. Its high fructose content can pose health risks if consumed in large amounts, so it's crucial to be mindful of your overall sugar intake.
Agave nectar is a delicious and versatile natural sweetener that offers some nutritional benefits over traditional sugar and other sweeteners. Its lower glycemic index, antioxidant properties, and potential digestive health benefits make it an attractive option for those looking to reduce their sugar consumption. However, it is essential to use agave nectar in moderation and consider it as part of a balanced diet. By understanding the uses and benefits of agave nectar, you can make an informed decision about incorporating it into your culinary repertoire.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6611)
Date:
June 03, 2024 04:15 PM
In a world where health consciousness is increasingly important, finding the right sweetener can be a game changer. One such alternative that has gained significant attention is Stevia. Known for its zero-calorie content, Stevia offers a natural sweetness without the drawbacks associated with sugar. This article examines the properties of Stevia, how it’s harvested, its sweetness compared to sugar, and its benefits for those managing diabetes.
Stevia is a natural sweetener derived from the leaves of the Stevia rebaudiana plant, native to South America. Unlike artificial sweeteners, Stevia is completely natural and has been used for centuries by indigenous people in countries like Brazil and Paraguay. The leaves of the plant contain sweet-tasting compounds known as steviol glycosides, which are the primary components used in Stevia sweeteners found on shelves today.
Traditionally, Stevia leaves are harvested by hand. Farmers usually pluck the mature leaves, which are then dried to maintain their sweetness. Once dried, these leaves can be used in their whole form, or they can be processed to extract the steviol glycosides. Modern extraction methods involve soaking the leaves in water and then processing the extract to remove impurities. This results in a highly concentrated sweetener that is hundreds of times sweeter than sugar.
When it comes to sweetness, Stevia stands out. Stevia is approximately 200 to 300 times sweeter than sucrose (table sugar). This means a very small amount of Stevia is needed to achieve the desired level of sweetness, which also makes it an efficient option for those looking to cut down on sugar intake. However, it’s important to note that Stevia doesn’t have the exact same taste profile as sugar. Some people describe its sweetness as having a slight, licorice-like aftertaste, which not everyone finds appealing.
For individuals managing diabetes, Stevia can be an invaluable part of their diet. One of the primary concerns for people with diabetes is managing their blood sugar levels. Traditional sugar can cause spikes in blood glucose, making it difficult to control diabetes symptoms. Stevia, on the other hand, does not contain carbohydrates and has no impact on blood glucose levels. This makes it a suitable alternative for those who need to keep their sugar levels in check. Moreover, using Stevia can help diabetic individuals enjoy sweet foods and beverages without the fear of negatively affecting their health. The zero-calorie aspect of Stevia also contributes to maintaining a healthier weight, which is a crucial factor in managing diabetes.
In addition to its zero-calorie feature, Stevia also offers several nutritional and health benefits. Some research suggests that Stevia may help in lowering blood pressure and improving cholesterol levels. These potential benefits make Stevia not just a sugar substitute, but a supplement that can contribute to overall well-being.
Stevia leaves are rich in antioxidants, which help to combat oxidative stress in the body. Oxidative stress is linked to various chronic diseases, including heart disease and cancer. By incorporating Stevia into your diet, you might benefit from its antioxidant content, aiding in the reduction of inflammation and promoting better health.
Stevia is versatile and can be used in a variety of culinary applications. It’s available in different forms such as powders, liquid extracts, and even whole leaves. You can use Stevia to sweeten beverages like tea and coffee, baked goods, desserts, and even savory dishes that require a touch of sweetness. However, due to its high sweetness level, it is recommended to start with a small amount and adjust according to taste. Keep in mind that Stevia might behave differently than sugar in recipes, particularly in baking. Sugar contributes to the texture and volume of baked goods, while Stevia does not. Therefore, recipes using Stevia may require additional adjustments for the best results.
Growing and harvesting Stevia can be advantageous from both economic and environmental perspectives. Stevia plants require less land and water compared to sugar cane or beet crops, making it a more sustainable option in the long run. Additionally, Stevia farming can provide economic opportunities for communities in developing countries where the plant is grown.
Stevia stands out as an exceptional zero-calorie sweetener, especially beneficial for those managing diabetes and looking to reduce their calorie intake. Its natural origin, coupled with its impressive sweetness and array of health benefits, make it a compelling alternative to traditional sugar and artificial sweeteners. Whether you are looking to alter your dietary habits or manage a health condition like diabetes, Stevia offers a promising solution for a healthier sweetening choice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6610)
Date:
May 31, 2024 11:05 AM
Stevia, a natural sweetener that has become globally popular in recent years, boasts a rich history spanning centuries. This article delves into the origins and historical significance of stevia, shedding light on its traditional use by indigenous peoples and its evolution into a mainstream alternative to sugar.
Stevia, scientifically known as Stevia rebaudiana, originates from South America. This small, green plant is part of the Asteraceae family, which also includes daisies and sunflowers. The leaves of the stevia plant contain sweet compounds known as steviol glycosides, which are responsible for its sweetness.
The historical journey of stevia begins with the Guaraní people of Paraguay and Brazil, who have used the plant for over 1,500 years. The Guaraní referred to stevia as "ka'a he'ê," which translates to "sweet herb." They traditionally used stevia leaves to sweeten beverages like yerba maté, a popular herbal tea, and to enhance the flavor of various traditional dishes. Stevia wasn't just a sweetener for the Guaraní; it also held medicinal importance. The leaves were used to treat a variety of conditions, including burns, stomach issues, and as a general tonic. This dual use of stevia as both a sweetener and a medicinal plant highlights its invaluable role in indigenous culture.
The modern history of stevia began in the 16th century when European explorers first arrived in South America. Spanish botanist and physician Pedro Jaime Esteve (1500–1556) is often credited with the early European studies on stevia, although the plant was not widely documented until later. Interest in stevia grew in the early 20th century when it was scientifically studied by Paraguayan chemist Ovidio Rebaudi. Rebaudi analyzed the sweet properties of stevia leaves and confirmed that they were much sweeter than sugar, which caught the attention of the scientific community.
In the 1970s, stevia began gaining traction in Japan as the country sought alternatives to artificial sweeteners. Japanese researchers developed methods for extracting and refining steviol glycosides from stevia leaves, making it possible to use stevia as a commercial sweetener. The success of stevia in Japan set the stage for its global acceptance.
Stevia's rise in popularity can be attributed to its myriad of health benefits. Unlike sugar, stevia is calorie-free, making it an attractive option for those managing their weight. Additionally, stevia has a negligible effect on blood glucose levels, which is beneficial for individuals with diabetes or those monitoring their carbohydrate intake. Moreover, steviol glycosides are stable at high temperatures, making stevia a versatile sweetener suitable for cooking and baking. This thermal stability, combined with its natural origin, has positioned stevia as a preferred option for health-conscious consumers.
The journey of stevia to becoming a global sweetener has involved rigorous scientific scrutiny and regulatory approval. In 2008, the United States Food and Drug Administration (FDA) granted stevia the status of "Generally Recognized As Safe" (GRAS), which paved the way for its use in a wide range of food and beverage products. Following the FDA's approval, other countries, including those in the European Union, Canada, and Australia, also approved the use of stevia in food and beverages. Today, stevia is found in everything from soft drinks to baked goods, reflecting its widespread acceptance and global reach.
Despite its many advantages, the path to widespread adoption of stevia has not been without challenges. One of the initial hurdles was the aftertaste associated with some of the early stevia extracts. However, advances in extraction and formulation techniques have significantly improved the taste profile of stevia, making it more palatable for consumers. Another challenge has been ensuring the sustainable cultivation of stevia. As demand grows, it is essential to implement agricultural practices that support environmental sustainability and fair labor conditions for farmers.
The future of stevia holds exciting possibilities as ongoing research continues to explore new applications and improvements. Scientists are currently investigating the potential of stevia extracts in providing health benefits beyond sweetness, such as their antioxidant properties and possible roles in managing certain health conditions. Innovations in biotechnology are also paving the way for the development of new stevia varieties with enhanced sweetness and improved agronomic traits. These advancements could further solidify stevia's position as a key player in the global sweetener market.
The history of stevia is a fascinating journey from the rainforests of South America to the shelves of supermarkets around the world. From its traditional use by the Guaraní people to its rediscovery by European explorers and subsequent global adoption, stevia has proven to be a remarkable sweetener with enduring significance. As the modern world continues to prioritize health and wellness, stevia's natural sweetness offers a much-needed alternative to sugar, promising a future where we can enjoy the sweetness of life without compromising our health.
If you've been searching for a healthier way to satisfy your sweet tooth, the journey of stevia offers a compelling reason to make the switch. With its rich history rooted in traditional use by the Guaraní people, and its scientifically-backed benefits recognized globally, stevia stands out as a truly remarkable sweetener. Free from calories and gentle on blood glucose levels, it's an excellent choice for both weight management and diabetes care. Plus, its versatility in cooking and baking means you won't have to compromise on your favorite recipes. Join the growing number of health-conscious consumers who are choosing stevia for a naturally sweet life. Explore its various forms—from whole leaves to refined steviol glycosides—and incorporate this natural sweetener into your diet today. Embrace the future of sweetening and enjoy the benefits of stevia for yourself and your loved ones.
Stevia is a natural sweetener derived from the leaves of the Stevia rebaudiana plant, which is native to South America. It has been used for centuries by the Guaraní people and is known for being much sweeter than sugar while containing zero calories.
Stevia can be used in various forms, including whole leaves, powdered extracts, and liquid concentrates. It is commonly used to sweeten beverages, baked goods, and other foods. Thanks to its stability at high temperatures, stevia can also be used in cooking and baking.
Yes, stevia is considered safe for consumption. The United States Food and Drug Administration (FDA) has granted stevia the status of "Generally Recognized As Safe" (GRAS). It has also been approved for use in many other countries, including those in the European Union, Canada, and Australia.
Stevia can be an effective tool for weight management because it contains no calories. Replacing sugar with stevia in your diet can help reduce overall calorie intake, which may contribute to weight loss or maintenance.
Stevia is suitable for people with diabetes as it has a negligible effect on blood glucose levels. This makes it a preferable alternative to sugar for those needing to monitor their carbohydrate intake. However, it is always best to consult with a healthcare provider before making any significant changes to your diet.
Stevia is generally well-tolerated and considered safe for most people. However, some individuals may experience mild side effects, such as digestive discomfort, when consuming large amounts. It is advisable to use stevia in moderation.
Stevia is known to be much sweeter than sugar, and its taste can vary depending on the form used and the specific product. Early versions of stevia extracts were noted for having a slight aftertaste, though modern formulations have significantly improved the taste profile.
Stevia is typically grown in subtropical and tropical climates. Sustainable cultivation practices are essential as the demand for stevia increases. These practices include using environmentally friendly agricultural methods and ensuring fair labor conditions for farmers.
Stevia has the potential to be more sustainable than traditional sugar crops. It requires less land and water to produce the same level of sweetness, which can reduce the environmental impact associated with sugar cultivation.
Yes, stevia can be used in baking due to its high-temperature stability. However, because it is much sweeter than sugar, recipes may need to be adjusted to account for its intensity. Many commercially available stevia sweeteners come with specific usage guidelines for cooking and baking.
Yes, stevia products come in various forms, including whole leaves, powdered extracts, and liquid concentrates. Some products are blended with other sweeteners or filler ingredients to better mimic the taste and texture of sugar.
Stevia is a natural sweetener, which sets it apart from many artificial sweeteners. It is derived from a plant and does not undergo extensive chemical processing. Many consumers prefer stevia because it is perceived as a more natural and healthier option.
Ongoing research on stevia explores its potential health benefits beyond sweetness, such as its antioxidant properties and possible roles in managing certain health conditions. Innovations in biotechnology are also working to develop new stevia varieties with enhanced sweetness and other desirable traits.
Stevia products are widely available at VitaNet LLC. Stevia can be found in the baking aisle or the section dedicated to natural and alternative sweeteners. By understanding the benefits and uses of stevia, you can make an informed decision about incorporating this natural sweetener into your diet. With its rich history, proven health benefits, and versatility, stevia offers a compelling alternative to traditional sugar.
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Date:
May 30, 2024 12:46 PM
Stevia has garnered attention as a natural, calorie-free sweetener that can seamlessly replace sugar in various recipes. Derived from the leaves of the Stevia rebaudiana plant, this sweetener is known for its ability to provide a satisfying sweetness without the health drawbacks associated with traditional sugar. In this article, we'll explore creative recipes and practical tips for incorporating stevia into everyday cooking and baking, allowing you to enjoy your favorite dishes without compromising on taste.
Before diving into recipes, it's important to understand why stevia is a fantastic alternative to sugar. Here are some of the key benefits:
Stevia can effectively replace sugar in many baking recipes, but it's essential to remember that it is much sweeter than sugar. Typically, a teaspoon of stevia extract can replace a cup of sugar, but always refer to specific conversion charts provided by stevia product manufacturers.
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Beyond baking, stevia can introduce a hint of sweetness to savory dishes as well. Here are some innovative ways to include stevia in your everyday cooking.
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Stevia is also great for sweetening beverages. Whether it’s a refreshing iced tea or a nutritious smoothie, stevia can add the perfect touch of sweetness.
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Stevia opens up a world of culinary possibilities, letting you enjoy the sweetness of your favorite recipes without the drawbacks of sugar. From delectable desserts like chocolate chip cookies to savory innovations like homemade BBQ sauce, the versatility of stevia can enhance all your culinary creations. Remember, the key is to experiment and adapt recipes to suit your taste, making stevia a valuable and enjoyable part of your cooking repertoire.
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Date:
May 29, 2024 11:28 AM
Vitamin B12, or cobalamin, is crucial for red blood cell production, DNA synthesis, and nervous system health. Among its many roles, one of the most vital is its contribution to energy production and metabolism. This article delves into how Vitamin B12 affects energy levels, with a particular focus on its importance for vegetarians and vegans.
Vitamin B12 is a water-soluble vitamin that is naturally found in animal products such as meat, dairy, and eggs. It is primarily responsible for converting food into ATP (adenosine triphosphate), which the body uses for energy. B12 is also crucial in the formation of red blood cells, which carry oxygen to every part of the body, and in maintaining the health of nerve cells.
Vitamin B12 is a key player in metabolism, a complex set of chemical reactions in our body that convert food into energy. One of the primary ways B12 contributes to metabolism is through its involvement in the Krebs cycle, a series of reactions that produce ATP (adenosine triphosphate), the body's primary energy currency. During the Krebs cycle, Vitamin B12 helps convert fats and proteins into energy, ensuring that the body has a constant supply of fuel to perform everyday tasks.
Vitamin B12 is also essential for DNA synthesis and cell division. It works closely with folate (Vitamin B9) to synthesize DNA during cell division. Rapidly dividing tissues, such as red blood cells, require an adequate supply of B12. A deficiency in this vitamin can lead to megaloblastic anemia, a condition where red blood cells are larger than normal and not as effective in transporting oxygen, thereby causing fatigue and weakness.
One of the significant challenges for vegetarians and vegans is getting enough Vitamin B12, as it is predominantly found in animal products. Plant-based diets generally lack this vitamin, putting individuals at risk of deficiency. However, several fortified foods and supplements can help prevent this deficiency.
Many plant-based milk alternatives, breakfast cereals, and nutritional yeasts are now fortified with Vitamin B12. For instance, a cup of fortified soy milk can provide about 50% of the daily recommended intake of B12. Additionally, B12 supplements are readily available and can be an effective way for vegetarians and vegans to ensure they get their daily dose. It's crucial to choose a supplement that meets the dietary needs and preferences of the individual.
A lack of Vitamin B12 can result in various health problems like fatigue, weakness, constipation, loss of appetite, and weight loss. In severe cases, it may lead to neurological issues such as numbness and tingling in the hands and feet, balance difficulties, depression, confusion, and memory loss. Given these risks, it's essential for vegetarians and vegans to monitor their B12 levels.
Adequate intake of Vitamin B12 can significantly enhance energy levels. Since B12 is involved in converting food into ATP, sufficient levels of this vitamin can help ensure that the body efficiently produces and uses energy. Individuals who maintain appropriate B12 levels often report feeling more energetic and less fatigued.
By ensuring a sufficient supply of B12, vegetarians and vegans can support their metabolic functions. A well-functioning metabolism is crucial for maintaining body weight, supporting muscle function, and ensuring overall vitality. Improved metabolic function also means better handling of the foods consumed, leading to more stable energy levels throughout the day.
Vitamin B12 is essential for producing neurotransmitters that regulate mood. Adequate levels of B12 can help prevent mental health issues such as depression and brain fog, which are often associated with fatigue and low energy levels. Regular intake of B12, either through diet or supplements, can contribute to better mental clarity and emotional well-being.
B12 is crucial in maintaining the myelin sheath, a protective coating around nerves. A healthy nervous system ensures that signals travel efficiently between the brain and the rest of the body. This not only helps in preventing neurological issues but also ensures that the body's energy systems operate smoothly.
For vegetarians and vegans, regular blood tests are an effective way to monitor B12 levels. These tests can help identify a deficiency early on, allowing individuals to take corrective measures before any severe symptoms manifest.
A well-rounded, balanced diet that includes fortified foods can help meet the daily recommended intake of Vitamin B12. Incorporating a variety of B12-fortified foods into every meal ensures a steady supply of this vital nutrient.
For those who struggle to get enough Vitamin B12 through diet alone, supplements are an excellent option.
When selecting a Vitamin B12 supplement, methylcobalamin, or methyl B12, is often recommended as the best form. It has superior bioavailability compared to cyanocobalamin, making it easier for the body to absorb and utilize. Methyl B12 doesn't need conversion in the body to be effective, leading to quicker uptake and immediate benefits. For vegetarians and vegans at higher risk of B12 deficiency, methyl B12 is especially beneficial for maintaining optimal B12 levels effectively. Including this form in your supplement routine can boost energy, mental clarity, and support metabolic and nervous system functions.
Raising awareness about B12 is key for vegetarians and vegans to prevent deficiencies. Health programs can educate on maintaining adequate levels through diet and supplements.
Vitamin B12's role in energy production and metabolism is indisputable. Vegetarians and vegans can struggle to get enough B12 from plant-based diets, but fortified foods and supplements offer solutions. Understanding B12's importance and taking action can boost energy, metabolism, and well-being. Regular monitoring, a balanced diet, and appropriate supplementation are key strategies to prevent deficiency and maintain optimal health.
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Date:
May 28, 2024 03:46 PM
In recent years, there's been a significant uptick in the awareness of vitamin and mineral deficiencies across global populations. Micronutrients, though required in minuscule amounts, play a critical role in bodily functions, from metabolism to immunity. Despite advancements in healthcare and education, many individuals are still unaware of their own nutritional gaps, with modern diets contributing significantly to these deficiencies.
The rise in convenience foods, which are often calorie-dense but nutrient-poor, has significantly impacted nutritional intake. Fast foods, processed meals, and sugary snacks have become staples in many diets, particularly in urban settings. These foods are typically low in essential vitamins and minerals such as vitamin D, vitamin B12, iron, and magnesium. As people increasingly rely on these quick, palatable options, it often comes at the expense of nutrient-rich fruits, vegetables, lean proteins, and whole grains.
Another contributing factor to vitamin deficiencies is the shift in lifestyle patterns. Longer work hours, increased screen time, and reduced physical activity mean that individuals spend less time outdoors. This has a particularly detrimental effect on vitamin D levels, which are naturally synthesized when skin is exposed to sunlight. Furthermore, high-stress levels and poor sleep quality can deplete essential nutrients, exacerbating the issue.
Changes in agricultural practices have also had an inadvertent impact on the micronutrient content of food. Soil depletion, the use of chemical fertilizers, and genetically modified crops can lead to lower levels of vitamins and minerals in produce. Consequently, even those who consume fruits and vegetables regularly might not be getting the expected nutrient benefits.
It is becoming increasingly clear that the widespread consumption of fast food plays a significant role in the rise of vitamin deficiencies. Fast food items are often designed to be highly palatable and energy-dense. However, they are typically laden with unhealthy fats, sugars, and sodium while lacking essential nutrients. Regularly consuming these foods can lead to an imbalance in diet, where the body might get ample calories but insufficient vitamins and minerals. For instance, studies have shown that diets high in fast food are linked to lower intakes of vitamins A and C, dietary fiber, calcium, and iron. These deficiencies can trigger a range of health issues, from diminished immune function and poor bone health to increased susceptibility to chronic diseases.
To counteract these dietary deficiencies, many nutrition experts recommend incorporating a food-based multivitamin into daily routines. Unlike synthetic supplements, food-based multivitamins are derived from whole foods and contain a spectrum of vitamins and minerals in their natural forms, which can be more readily absorbed and utilized by the body.
When choosing a food-based multivitamin, look for products that:
The rise in micronutrient deficiencies is a concerning trend that underscores the importance of balanced nutrition. While modern lifestyles and dietary habits contribute significantly to this issue, there are effective ways to address it. Reducing the intake of nutrient-poor fast foods and incorporating food-based multivitamins can help bridge the gap and support overall nutritional needs. By making informed dietary choices, individuals can foster better health and mitigate the risks associated with vitamin and mineral deficiencies.
Understanding the impact of micronutrient deficiencies on overall health is the first step towards making informed dietary choices. By addressing nutritional gaps and prioritizing whole, nutrient-rich foods, you can significantly improve your well-being. We invite you to explore our range of high-quality, food-based multivitamins designed to complement your daily diet and ensure you receive the essential nutrients your body needs.
Don't wait until deficiencies affect your vitality. Visit our online store to find the perfect multivitamin for your lifestyle. Our products are crafted with organic, non-GMO ingredients, and are free from unnecessary additives and fillers. Embrace a healthier you with the power of natural, food-based nutrients.
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Date:
December 07, 2023 12:12 PM
Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body. While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption. GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age. The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels. In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body. This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form. But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them. So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing! When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ. Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds. During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances? But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker! The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning. So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being! Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells. To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes. The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group. The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver. Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels. Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy. In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management. By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions. Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores. Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects. Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract. The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women. In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH. Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin. The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities. In summary, the administration of
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Date:
November 04, 2023 10:53 AM
Magnesium is an essential mineral for the body, playing a crucial role in the regulation of blood pressure and numerous other bodily functions. The shortcoming of this nutrient can be addressed through the consumption of magnesium glycinate, a supplement also known as magnesium diglycinate and magnesium bisglycinate. Key Roles of Magnesium This article delves into the details of magnesium glycinate, looking at its benefits, potential side effects, the recommended dosage, and more. The human body needs a significant amount of magnesium for optimal function. Although the best way to obtain nutrients is in their natural form, supplements like magnesium glycinate are available to enhance magnesium intake in individuals with low levels. Benefits of this supplement include: Precautionary Measures Sources of Magnesium Glycinate Nutritional sources rich in magnesium include legumes, nuts, seeds, whole grains, spinach, fortified breakfast cereals, yogurt, milk, and other dairy products. Recommended Dosage The amount of magnesium glycinate to be taken can vary. It is advised to consult a doctor before starting a magnesium glycinate regimen. Potential Side Effects Magnesium glycinate, like other dietary supplements, can cause side effects such as nausea, abdominal cramps, and diarrhea when taken in large or frequent doses. However, a study from 2013 indicated that magnesium glycinate is less likely to induce diarrhea compared to other magnesium supplements. Extreme doses could lead to magnesium toxicity, resulting in more severe side effects. Easy Ways to Consume More Magnesium One effective method of increasing magnesium intake is by incorporating dietary supplements into your daily regime. For instance, Solaray Magnesium Glycinate is a popular supplement that is widely recognized for its efficacy. It is an easily digestible form of magnesium that is gentle on the stomach and less likely to induce diarrhea. Solaray's supplement provides an accessible option for those looking to supplement their diet with magnesium, especially for individuals who might struggle to meet their nutritional requirements through diet alone. Conclusion Magnesium glycinate can be a beneficial supplement for individuals with magnesium deficiency. However, caution must be exercised in its consumption, with potential side effects and individual health conditions taken into account. As always, it is best to seek medical advice before starting a new supplement regimen.
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Date:
August 09, 2023 02:11 PM
What is Stevia?
stevia is an all-natural, non-GMO, and calorie-free sweetener made from the leaves of the Stevia rebaudiana plant. It's a safe alternative to sugar that doesn't raise your blood sugar levels and has a 0 glycemic index. Its sweet taste comes from steviol glycosides, which are extracted from the leaves and purified. Stevia is commonly used to sweeten drinks, baked goods, and even savory dishes.
How is Stevia Different from Other Sweeteners?
Unlike artificial sweeteners such as aspartame and saccharin, stevia is a natural sweetener that doesn't have any of the negative health effects that come with consuming artificial additives. It's a safer option to sugar that doesn't affect insulin levels, making it beneficial for diabetics or those who are watching their sugar intake. Additionally, stevia has a much sweeter taste compared to traditional sugar, so only a small amount is needed to achieve the desired sweetness.
How to Use Stevia?
Stevia can be used in the same way as sugar when baking or cooking, but with way less quantity. For example, if a recipe calls for 1 cup of sugar, just 1/2 teaspoon of Kal stevia will give the equivalent sweetness. However, it's important to keep in mind that stevia can taste slightly different from sugar and may not always be an exact substitute. Start with smaller amounts and increase as needed and you'll get the hang of it.
Are There Any Side Effects of Stevia?
Stevia has been used worldwide and is found to be one of the safest all natural sweetener on the market. There have been no known negative side effects associated with the use of stevia other than the potential for mild gastrointestinal symptoms if consumed in large amounts. Generally, most don't consume enough to cause any issues.
Stevia comes in powder and liquid forms. Liquid tends to mix instantly and is preferred by most people.
If you're looking to reduce your sugar intake while still satisfying your sweet tooth, Kal brand stevia may be an excellent alternative for you. With its natural origins, numerous health benefits, and delicious taste, it's not hard to see why so many people are switching over to this sweetener over the traditional chemical-laden sugars of the past. Try Kal brand stevia in your next recipe or tea and let your taste buds be the judge!
If your interested, just add to cart for best price!
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Date:
August 04, 2023 02:09 PM
The typical Western diet is largely comprised of processed foods, which are notoriously high in processed table salt. This results in an imbalance in the sodium to potassium ratio, a significant health concern. Sodium is necessary for a variety of bodily functions; however, too much can be detrimental, leading to hypertension and other cardiovascular diseases. Simultaneously, potassium is often neglected, despite its crucial role in muscle function, nerve signaling, and balancing fluids.
The general dietary advice suggests a potassium to sodium intake ratio of 3:1. However, the reality in diets, particularly those in America, often sees this ratio inverted. The excessive sodium consumption is linked to a myriad of health complications, including high blood pressure and heart disease. Conversely, potassium, a mineral that aids in nerve function and muscle control, is consumed in insufficient quantities. This is a troubling trend that underscores the importance of dietary change towards natural, unprocessed foods.
The importance of potassium is often overshadowed by the emphasis on limiting sodium for reducing chronic disease risk factors. Potassium plays an essential role in maintaining healthy blood pressure levels by counteracting the effects of sodium. Furthermore, the mineral is crucial for other functions like heart and muscle cell functioning, nerve transmission, and maintaining fluid balance.
A study published in the New England Journal of Medicine discovered that individuals with the lowest risk for heart complications or death from any cause were those consuming between four to six grams of sodium per day. This is a fascinating discovery, as this intake is significantly higher than the U.S. daily recommended limits. It suggests a need for a reconsideration of current sodium intake guidelines.
Another consideration to balance the sodium-potassium ratio is the type of salt consumed. Unprocessed, natural salts like sea salt and Himalayan salt contain higher potassium levels compared to standard table salt. These natural salts provide a variety of minerals and trace elements that contribute to our overall health and wellness. It's crucial to note that switching to natural salt should be part of a broader shift towards a diet rich in fresh, unprocessed foods.
Why You Should Focus on Increasing Potassium
While it's beneficial to monitor and moderate sodium intake, it's equally important to shift our focus towards increasing potassium consumption. Potassium-rich foods, such as leafy green vegetables, bananas, potatoes, and beans, not only contribute to a well-rounded and nutritious diet but also help in maintaining an optimal sodium-potassium balance in the body. A high potassium intake can counteract the effects of sodium, aiding in blood pressure regulation and reducing the risk of cardiovascular diseases. Moreover, an elevated potassium level supports various bodily functions, including nerve transmission, muscle contraction, and fluid balance. Thus, prioritizing potassium intake forms a cornerstone for an overall healthier dietary approach. It is recommended that individuals consume 5 grams of potassium daily and potassium to salt ratio should be 2 to 1. To boost potassium intake, one can take a potassium supplement or add the following foods to their diet or both: Watermelon, Orange juice, Boiled red potatoes, Avocado, Bananas, Cantaloupe, Oranges, Coconut water, Tomatoes, Yogurt, Winter squash, and Wild-caught salmon.
Why Low-Salt Advice Can Be Harmful
Contrary to popular belief, adhering to low-salt advice can sometimes pose risks to certain individuals. While it is true that excessive sodium intake can lead to high blood pressure and heart problems, sodium still plays a vital role in our bodies. It assists in nerve conduction, muscle contraction, and maintaining the body's fluid balance.
In fact, low sodium levels in the body, a condition known as hyponatremia, can lead to symptoms such as headache, nausea, fatigue, and in severe cases, coma or even death. Moreover, a low-salt diet may lead to increased levels of cholesterol and triglycerides, hormonal imbalances and insulin resistance. This can potentially elevate the risk of developing cardiovascular disease.
Low-salt diets can also exacerbate the risk of certain health conditions. For instance, individuals with conditions like Addison's disease or certain kidney disorders, where the body struggles to maintain a balance of electrolytes, might find a low-salt diet harmful.
Therefore, it is crucial to balance the intake of sodium, considering both the potential risks associated with too much, or too little, sodium. The key is to consume sodium from natural and unprocessed sources, such as Himalayan salt, fruits, vegetables, grains, and lean meats, which also provide a host of other nutrients necessary for overall health. As with most things in nutrition, moderation and balance seem to hold the answer rather than extreme restriction. The RDA - recommended daily allowance of sodium is 3.5 grams. It is advised to consume 3.5 grams of natural salt each day by way of foods or combination of foods plus Himalayan salt to reach that goal.
The Impact of Excessive Salt Intake on Certain Health Conditions
While moderate salt intake is vital for normal physiological functions, its excessive consumption can have detrimental effects, particularly for individuals with certain health conditions. For instance, endocrine disorders, high aldosterone levels, Cushing's syndrome, and elevated cortisol levels can all heighten the body's sensitivity to sodium, making it even more essential to monitor and limit salt intake.
Endocrine disorders, which involve imbalances in the body's hormone production, can often lead to increased sodium retention, exacerbating issues of water retention and swelling. Similarly, high aldosterone levels, a hormone that regulates sodium and potassium balance, can cause the body to retain excessive sodium, leading to high blood pressure and potential damage to the cardiovascular system.
Cushing's syndrome, a condition characterized by excessive cortisol production, can lead to a host of symptoms, including high blood pressure and rapid weight gain, both of which can be intensified by high sodium intake. The excessive cortisol found in Cushing's syndrome promotes sodium retention, further elevating the risk for hypertension.
Similarly, elevated cortisol levels, even outside of Cushing's syndrome, can lead to heightened sodium retention, contributing to high blood pressure, fluid retention, and an imbalance of electrolytes. Therefore, individuals with these conditions should be particularly mindful of their sodium intake.
In these scenarios, reducing salt consumption can help mitigate the associated health risks and symptoms. Switching to a diet rich in whole, unprocessed foods, and taking conscious steps to limit the use of added table salt can play a crucial role in managing these health conditions. As always, it is essential to seek personalized advice from a healthcare professional, as individual needs may vary.
In summary, while salt is often villainized in the health community, its consumption, especially from natural sources, is vital for maintaining bodily functions like nerve conduction, muscle contraction, and fluid balance. However, excessive or inadequate sodium intake can have adverse health effects, such as hypertension, imbalances in cholesterol and triglycerides, and even hyponatremia in severe cases. Certain health conditions, including endocrine disorders, high aldosterone levels, Cushing's syndrome, and elevated cortisol levels, can also exacerbate these risks, making it crucial for individuals with these conditions to carefully monitor their salt intake. On the other hand, increasing potassium intake can help maintain an optimal sodium-potassium balance, reducing blood pressure and lowering the risk of cardiovascular diseases. In a nutshell, moderation and balance are key in sodium consumption, but the emphasis should be on consuming more potassium-rich foods to ensure your potassium intake is higher than sodium levels which will ensure a healthier dietary approach.
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Date:
July 27, 2023 12:12 PM
What if there existed a form of thiamine that was more bioavailable and physiologically active than the conventional form we all know about? Well, that form does exist, and it is called Benfotiamine. Benfotiamine has been gaining popularity lately, especially among people dealing with diabetes and other metabolic disorders. But what exactly is Benfotiamine, and what makes it different? Lets explore Benfotiamine, its bioavailability, and its physiological effects.
Thiamine, also known as Vitamin B1, is a nutrient that plays a crucial role in energy production, nerve function, and metabolism. It is a water-soluble vitamin, which means it dissolves in water and is not stored by the body. However, conventional forms of thiamine have a limited ability to cross cell membranes and are easily excreted out of the body, rendering it ineffective for some individuals. This is where Benfotiamine comes in; it is a modified form of Vitamin B1 that is fat-soluble, highly bioavailable, and because cells are wrapped in lipid fat this form of B1 is capable of crossing cell membranes with ease.
Since our cell membranes are composed of lipids, fat-soluble nutrients can easily penetrate the cell barrier and get into living cells where the vitamin is needed. Upon entering the bloodstream, benfotiamine is converted to thiamin pyrophosphate (TPP), the biologically active co-enzyme of thiamin, which is responsible for energy metabolism. By raising the blood levels of TPP, benfotiamine has been shown to support glucose metabolism, reduce oxidative stress and inflammation, and protect against the damage caused by high levels of advanced glycation end products (AGEs).
In addition to its bioavailability, benfotiamine has been shown to have several physiological effect on the body. One of the key enzymes that benfotiamine influences is transketolase, which is involved in the pentose phosphate pathway, a metabolic pathway that generates NADPH, a vital molecule that protects cells against oxidative stress. By stimulating transketolase, benfotiamine supports the diversion of excess glucose to the pentose phosphate pathway, thereby reducing the production of reactive oxygen species and increasing the production of NADPH.
Another significant benefit of benfotiamine is that it helps protect the nervous system. Chronic high blood glucose levels are known to cause oxidative stress and to damage the peripheral and central nervous systems. However, benfotiamine has been shown to help lower oxidative stress markers and reduce the risk of nerve damage. This can in turn help reduce pain, numbness, and tingling sensations associated with nerve damage, making it a promising adjunct therapy for people with diabetic neuropathy.
In Summary: benfotiamine is a modified and bioavailable form of thiamine that offers unique benefits compared to conventional forms of Vitamin B1. Its fat-solubility enables it to cross cell membranes, raise levels of thiamin pyrophosphate, stimulate the transketolase enzyme, and support proper glucose metabolism. Its notable effects on the nervous system make it an attractive therapeutic agent for people with diabetic neuropathy. If you're seeking an alternative and highly effective form of thiamine, benfotiamine is definitely worth considering. Give it a try today!
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Date:
November 04, 2022 10:33 AM
Tart cherry is a type of cherry that is known for its sour taste. However, recent research has lead to increased interest in the cherry for its health-promoting benefits. Cherries contain anthocyanins, which are responsible for the red color of the fruit. Anthocyanins are considered antioxidants, which have free radical neutralizing properties.
Gout and Arthritis
One of the most well-known benefits of tart cherry is its ability to help the body fight gout and arthritis. Gout is a type of inflammatory arthritis that affects approximately 8.3 million people in the United States. symptoms include severe pain, swelling, and stiffness in the joints. Tart cherry has been shown to reduce these symptoms by reducing inflammation.
Heart Health
Tart cherries are also good for heart health. Several studies have shown that tart cherry intake can help reduce blood pressure and cholesterol levels. Additionally, tart cherries can help reduce inflammation markers in the blood, which is important for overall heart health.
Brain Health
Tart cherries are also being studied for their potential role in brain health. One study found that people who consumed tart cherry powder daily for 12 weeks had improved cognitive function and memory compared to those who did not consume the powder. Additionally, tart cherry intake has been shown to increase levels of melatonin, which is a hormone that helps regulate sleep cycles.
Overall, tart cherry is a nutritional powerhouse with many potential health benefits. If you're looking for a natural way to improve your gout or arthritis symptoms, lower your blood pressure or cholesterol levels, or memory and cognitive function, incorporating tart cherry into your diet is a great place to start.
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Date:
October 21, 2022 12:29 PM
Methylation is a process in the body that helps to produce DNA, keep hormones in balance, and support detoxification. You need methyl groups for this process to happen, and TMG (trimethylglycine) donates methyl groups to help with methylation. TMG also supports cardiovascular health and cognitive function while reducing inflammation.
Not sure if TMG is right for you? Keep reading to learn more about this methyl donor’s benefits.
Benefit #1: TMG Promotes Healthy Methylation
As we just touched on, one of the main benefits of TMG is that it promotes healthy methylation. As we know, methylation is important for DNA production, hormone balance, and detoxification support.
TMG provides the extra push of methyl groups needed to keep these processes running smoothly which is why it’s often taken as a supplement. If you have difficulty methylating or you have a genetic mutation that affects methylation, TMG may be a good supplement for you to consider. Check with your doctor first, of course!
Benefit #2: TMG Supports Cardiovascular Health
TMG also known as betaine, can improve cardiovascular health by reducing homocysteine levels. Homocysteine is an amino acid that at high levels has been linked to heart disease. While more research needs to be done in this area, initial studies are promising.
In one study of nearly 500 participants, researchers found that those who took TMG had lower levels of homocysteine than those who didn’t supplement with the nutrient [1]. While this doesn’t prove causation, it’s an interesting correlation worth noting—especially given that other studies have found similar results [2].
benefit #3: May Reduce Inflammation
Chronic inflammation has been linked to many diseases such as heart disease, arthritis, and even cancer. Some studies suggest that TMG may help reduce inflammation levels in the body [3]. In one animal study, rats given TMG had reduced lung inflammation compared to rats who weren’t given the supplement [4]. More research needs to be done in this area but initial studies are promising.
In Summary:
TMG is a nutrient known as a methyl donor which means it provides methyl groups needed for processes like DNA production and hormone balance. It also supports cardiovascular health and cognitive function while reducing inflammation. If you have difficulty methylating or you have a genetic mutation that affects methylation, TMG may be a good supplement for you to consider. Check with your doctor first!
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Date:
October 11, 2022 10:24 AM
DMG (Dimethylglycine) is a derivative of the amino acid Glycine that can be found in foods such as beans, brown rice and pumpkin seeds. DMG is an important methyl donor that participates in numerous biochemical pathways and is important for glutathione synthesis.* It also helps to promote optimal cellular oxygen utilization and supports the production of cells involved in the immune response.* While you may not have heard of DMG before, this compound plays an important role in keeping your body healthy. Read on to learn everything you need to know about DMG.
What is DMG?
DMG is a small molecule that donates methyl groups (CH3). Methylation is a process that occurs throughout the body and is essential for many biochemical reactions, including the production of DNA, enzymes, hormones and neurotransmitters. DMG is involved in methylation reactions involving homocysteine, folate, cobalamin (vitamin B12) and NADH.*
DMG also supports glutathione synthesis, which is important because glutathione is a key antioxidant that protects cells from damage caused by free radicals.* Furthermore, DMG promotes optimal cellular oxygen utilization and supports the production of cells involved in the immune response.*
Health Benefits of DMG
Because of its involvement in so many biochemical pathways, DMG has a wide variety of potential health benefits. Some of the most well-researched benefits include support for cardiovascular health, brain function and exercise performance.
Cardiovascular Health: DMG has been shown to support cardiovascular health by reducing blood pressure and improving blood flow.* It does this by dilating blood vessels and reducing inflammation.*
Brain Function: DMG has also been shown to support brain function, particularly in aging adults. One study found that supplementing with DMG improved mental clarity, memory and cognitive function in seniors.* The compound may also help improve focus and concentration.
Exercise Performance: Finally, DMG has been shown to improve exercise performance. One study found that athletes who supplemented with Dimethylglycine had increased VO2 max – a measure of cardiovascular fitness – compared to those who didn’t supplement.* Furthermore, another study found that cyclists who supplemented with DMG had reduced heart rate and perceived exertion during exercise.* This suggests that dimethylglycine may help improve endurance exercise performance.
In Summary:
DMG (Dimethylglycine) is a derivative of the amino acid Glycine that can be found in foods such as beans, brown rice and pumpkin seeds. This compound plays an important role in numerous biochemical reactions in the body and has a wide variety of potential health benefits. Supplementing with DMG 100-500 mg per day is generally well tolerated with few side effects reported. If you do experience any adverse effects when taking DMG ramp up your dosage slowly to give your body time to adjust.
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Date:
October 10, 2022 04:25 PM
DMAE (Dimethylaminoethanol) is an amino alcohol that is normally found in minute quantities in the brain. It is generally regarded as a precursor to the essential nutrient choline, which is needed for the brain to produce acetylcholine, a neurotransmitter involved in nerve signal transmission and healthy brain function.*
So what does that mean for you and your health? Let's take a closer look.
DMAE has been shown to have a positive effect on cognitive function and memory, which is why it's often referred to as "the memory vitamin." In one study, supplemented with DMAE showed significantly improved verbal skills and memory recall compared to those who did not take the supplement. Supplemental DMAE has also been shown to improve focus and reduce mental fatigue.
In addition to its cognitive benefits, DMAE has also been shown to have anti-inflammatory and antioxidant effects. Inflammation is linked to a number of chronic diseases, so reducing inflammation can lead to better overall health. The antioxidant effects of DMAE may help protect cells from damage caused by free radicals.
In Summary:
DMAE is a nutrient that is normally found in minute quantities in the brain. It plays a crucial role in cognitive function and memory recall, and has also been shown to have anti-inflammatory and antioxidant effects. If you're looking for a way to improve your cognitive function, memory, focus, or overall health, consider adding DMAE to your diet.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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Date:
October 10, 2022 01:39 PM
If you're looking for a natural way to support your joints, you may want to consider adding devil's claw to your list of options. This African herb has been used traditionally by tribal peoples for hundreds of years and more recently by Europeans and North Americans. Clinical studies have shown that the naturally occurring compounds in devil's claw may help to support joint comfort.* Let's take a closer look at why devil's claw is such a popular choice for those looking for joint support.
The active compounds in devil's claw include harpagoside, phytosterols, phenolic acids and flavonoids (kaempferol). These compounds work together to promote a healthy response to typical everyday joint stress.* In other words, they help to keep your joints healthy and comfortable even when faced with daily wear and tear.
One study in particular looked at the effects of devil's claw on knee joint discomfort. After eight weeks of supplementation with devil's claw, participants in the study reported significant improvements in their symptoms compared to those who did not take the herb.* Another small study found similar results, with participants reporting a decrease in pain and stiffness after taking devil's claw for eight weeks.**
In Summary:
If you're looking for a natural way to support your joints, devil's claw may be worth considering. Thanks to its abundance of active compounds, this African herb has been shown to promote a healthy response to typical everyday joint stress.* If you're thinking about giving it a try, be sure to talk to your doctor first to see if it's right for you.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
**https://pubmed.ncbi.nlm.nih.gov/31273865/
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Date:
September 24, 2022 10:26 AM
Pyruvate is a biochemical compound that’s involved in a number of metabolic processes in the body, including the metabolism of fat, proteins, and carbohydrates, the storage of glycogen, and the production of cellular energy.* Pyruvate is necessary for the citric acid cycle (or Krebs cycle), which is the process through which our cells produce energy in the form of adenosine triphosphate (ATP).* ATP is the body’s primary chemical fuel and powers many vital functions, including energy production, muscle contraction, and cellular fuel replenishment.* In short, pyruvate is essential for maintaining a healthy body. Let’s take a closer look at some of the specific ways in which pyruvate benefits the body.
The Role of Pyruvate in Metabolism
As we mentioned above, pyruvate plays an important role in metabolism—specifically, the metabolism of fat, protein, and carbohydrates. Pyruvate is involved in three different metabolic pathways: glycolysis (the breakdown of glucose), gluconeogenesis (the synthesis of glucose from non-carbohydrate sources), and the citric acid cycle (also known as the Krebs cycle or tricarboxylic acid cycle).*
The role of pyruvate in metabolism is twofold. First, pyruvate acts as an intermediary molecule in the conversion of glucose to ATP. Second, pyruvate initiates gluconeogenesis—the process by which glucose is synthesized from non-carbohydrate sources—by conversion into oxaloacetate.* This process occurs when there is not enough carbohydrate available for fuel or when additional glucose is needed for glycogen storage.*
The Benefits of Pyruvate Supplements
Pyruvate supplements have become popular in recent years as a weight loss aid.* Pyruvate has been shown to boost metabolism and promote thermogenesis—the process by which our bodies convert food into heat and energy.* In one study, participants who took 2.5 grams of pyruvate per day for six weeks lost significantly more weight and body fat than those who didn’t take pyruvate.* In another study, participants taking 3 grams of pyruvic acid per day for 12 weeks reduced their body fat mass by an average of 3.5 kilograms (7.7 pounds) compared to those taking a placebo.*
In Summary:
Pyruvate is a biochemical compound with a variety of functions in the human body. Most importantly, it plays a role in metabolism—specifically, the metabolism of fat, proteins, and carbohydrates. It also initiates gluconeogenesis—the process by which glucose is synthesized from non-carbohydrate sources—by conversion into oxaloacetate. Additionally, pyruvate has become popular in recent years as a weight loss aid due to its ability to boost metabolism and promote thermogenesis. Supplementing with pyruvic acid can help you lose weight and achieve your desired body composition.
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Date:
September 14, 2022 11:19 AM
Curcumin, the active polyphenolic extract of turmeric, is one of the most scientifically investigated plant compounds. Curcumin's health-supporting properties depend on its bioavailability. NOW Curcumin Phytosome is a unique form of curcumin complexed with phosphatidylcholine that clinically demonstrates enhanced absorption and bioavailability as compared with standard curcumin extracts. Clinical studies also show that curcumin phytosome is a powerful free radical scavenger, can help to support a balanced immune system response to normal metabolic stress, and can promote healthy joint mobility and flexibility.
The Benefits of Curcumin
Curcumin has been shown to offer a wide range of health benefits, thanks to its potent antioxidant and anti-inflammatory properties.* Some of the ways in which curcumin supports health include:
Brain Health: Curcumin has been shown to promote cognitive function and healthy brain aging.* It does this by reducing inflammation and oxidative stress, two factors that are known to contribute to age-related cognitive decline.*
Heart Health: Curcumin has been shown to support cardiovascular health by helping to maintain healthy cholesterol levels already within the normal range.* It also promotes healthy blood vessel function.*
Digestive Health: Curcuin supports a healthy inflammatory response in the digestive tract.* This helps to keep the gut lining healthy and promote regularity.*
In conclusion, curcumin is a powerhouse compound with numerous health-supporting properties. Thanks to its unique formulation as a complex with phosphatidylcholine, NOW Curcumin Phytosome is one of the most bioavailable forms of curcumin on the market today. If you're looking for a supplement to support brain, heart, and digestive health, look no further than curcumin phytosome!*
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Date:
September 12, 2022 04:22 PM
Berberine is a natural constituent of herbs such as goldenseal, Oregon grape, and barberry. Clinical studies have demonstrated that berberine helps to support already normal glucose and lipid metabolism.* Because berberine is known for its limited bioavailability, this product includes caprate (C10, a medium-chain triglyceride) to promote optimal absorption and maintenance of gastrointestinal comfort during berberine supplementation.*
Berberine has a long history of use in Traditional Chinese Medicine and Ayurveda for supporting already normal liver function and healthy digestion.* It is also one of the most well-studied botanicals for already normal glucose metabolism support, with research indicating it may work by activating an AMPK-dependent pathway.*
Berberine May Help To Support Normal Glucose Metabolism*
Berberine is a plant alkaloid with a long history of use in Traditional Chinese Medicine for promoting already normal liver function.* extraction process ensures a consistent level of berberine from batch to batch. In addition, this product provides 500 mg of berberine hydrochloride per vegetarian capsule.
Several clinical studies have demonstrated that berberine can help to support normal glucose metabolism in already healthy individuals when taken at dosages of 900 mg to 1,500 mg per day.* In a placebo-controlled human clinical trial involving subjects with prediabetes who were given 500 mg of berberine two times daily for 12 weeks, researchers observed improvements in already normal fasting blood sugar, HbA1c, and triglyceride levels (as well as increases in HDL-cholesterol) compared to placebo group.*
May Also Help To Support Lipid Metabolism*
In addition to its effects on already normal glucose metabolism, berberine has also been shown to help support lipid metabolism in already healthy individuals. In a 12-week, double-blind, placebo-controlled human clinical trial involving subjects with mild elevations in LDL cholesterol who were given 500 mg of berberine two times daily, researchers noted statistically significant decreases in total cholesterol and LDL cholesterol levels (along with increases in HDL cholesterol) compared to placebo group.*
Berberine is a potent botanical extract that has been traditionally used for supporting liver function and healthy digestion. Additionally, it is one of the most well studied botanicals for supporting already normal glucose metabolism. Numerous clinical trials show that it can help maintain already normal levels of fasting blood sugar as well as HbA1c and triglycerides. Furthermore, berberine has also been shown to promote already healthy lipid metabolism by supporting already normal levels of total cholesterol, LDL cholesterol, and HDL cholesterol. Therefore, if you are looking for an herbal supplement to support your overall health and well being, berberine is definitely worth considering.
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Date:
April 27, 2022 11:53 AM
Did you know that N Acetyl Cysteine has been around for decades? This powerful supplement was first discovered in the 1950s and has been used as a remedy for many health issues since then. We will discuss the many benefits of N Acetyl Cysteine and how you can start using it to improve your health!
Glutathione and aging
As we age, our natural levels of glutathione tend to decline. This is a major cause of many of the negative effects associated with the aging process, including reduced energy and slower recovery times after illness or injury. Fortunately, there are steps that we can take to increase our levels of glutathione, thus slowing down the aging process and keeping us feeling young and vibrant for longer. Some of these steps include eating a healthy diet rich in antioxidant-rich foods like fruits and vegetables, engaging in regular physical activity to improve circulation, and reducing stress levels through relaxation techniques like yoga and meditation. With these strategies in place, we can help to keep our bodies strong, boost our energy levels, and stay young well into old age. Fortunately, there is a supplement that could help, it is called N Acetyl Cysteine, this substance is a precursor to Glutathione and has been shown to boost glutathione levels.
What is N Acetyl Cysteine and what are its benefits?
N acetyl cysteine has been used as a supplement for many years, and its popularity is likely due to the many benefits it offers. The main function of this compound is to promote the production of glutathione, a powerful antioxidant that protects our bodies from oxidative stress and harmful free radicals. In addition, n acetyl cysteine has been shown to help reduce symptoms of certain mental health disorders, including anxiety and depression. Furthermore, studies have found that n acetyl cysteine may lower blood pressure and improve heart health by increasing blood flow and improving blood vessel function. Overall, it is clear that n acetyl cysteine has been an effective nutrient for many years and continues to be widely used by those looking for an easy way to support their health.
How can you start using N Acetyl Cysteine to improve your health?
N acetyl cysteine (NAC) is a powerful antioxidant that can help to protect cells from damage. It has been shown to be particularly effective in guarding against liver damage, and is often used as a treatment for hepatitis C. NAC can also help to improve lung function and relieve respiratory conditions such as bronchitis and asthma. In addition, NAC has been shown to boost levels of glutathione, which is a key molecule involved in detoxification. As a result, NAC can help to cleanse the body of harmful toxins and pollutants. NAC is available in supplement form, and can be taken orally or intravenously. It is generally well tolerated, with mild side effects such as nausea and vomiting occasionally reported. When taking NAC supplements, it is important to start with a lower dose and increase gradually as tolerated. Those with pre-existing medical conditions should always speak to their doctor before taking any new supplement. Overall, NAC is a safe and effective way to improve your health and protect your cells from damage.
What is the recommended daily dosage for N Acetyl Cysteine per day?
The standard recommended dosage for N-acetyl cysteine (NAC) is 600 mg per day. However, some studies have used dosages as high as 2,400 mg per day. The most common side effect of NAC is nausea, which can be minimized by taking the supplement with food. NAC is also sometimes used as a treatment for chronic bronchitis, and the recommended dosage for this condition is 1,200 mg per day. When used for this purpose, NAC is typically taken in divided doses of 600 mg twice per day. There is currently no consensus on the optimal dosage of NAC for any particular condition, and further research is needed to determine the ideal dosage for different applications. In acute circumstances, one might need 4000mg to 6000mgs daily in divided dosages, always work your way up to higher dosages as needed.
What are some of the most common uses for this supplement?
There are many different uses for NAC, or N-acetyl cysteine. This potent antioxidant supplement has been found to be effective in addressing a wide range of health concerns, including asthma and COPD, chronic sinusitis, liver disease, and particularly serious conditions such as cancer. Additionally, NAC has been shown to provide support for the immune system in general and may also serve as a detoxifying agent by helping to eliminate waste products like heavy metals from the body. Overall, there are numerous benefits to using NAC as part of a well-balanced diet. Whether you are looking to improve your respiratory health or strengthen your immune system, this versatile supplement can help you achieve your goals.
NAC composition
NAC, or N-acetyl cysteine, is a complex compound that is composed of various amino acids, including glutamate, glycine, and cysteine. These specific amino acids all play important roles in the function of NAC and affect its many beneficial properties. For example, glutamate increases metabolism and energy levels, while glycine promotes tissue healing and regeneration. Cysteine, on the other hand, facilitates the transport of oxygen and serves as a natural antioxidant. When taken together, these different components work synergistically to promote overall health and wellbeing by supporting key physiological processes such as digestion and immune response. Whether taken as a supplement or consumed through food sources like eggs and milk products, NAC is a versatile substance that is vital to many aspects of our daily health and well-being.
NAC and liver health
N-Acetyl-Cysteine (NAC) is a compound that has numerous benefits for liver health. Studies have shown that NAC can help to protect the liver from damage caused by alcohol and other toxins. It does this by helping to replenish levels of glutathione, a key antioxidant that helps to detoxify the liver. NAC also helps to reduce inflammation and improve blood flow to the liver. As a result, it can be an effective treatment for both acute and chronic Liver diseases. In addition, NAC has been shown to improve the overall health of people with Liver cirrhosis. Consequently, N-Acetyl-Cysteine is a compound that has many benefits for liver health and should be considered as part of any comprehensive treatment plan.
NAC, its sulfur content, and mucus elimination
NAC, or N-acetyl cysteine, is a sulfur-containing amino acid that plays an important role in mucus production and elimination. The sulfur content of NAC helps to thin mucus and make it less sticky, making it easier to clear from the lungs. In addition, NAC helps to break down mucus and remove it from the body. As a result, NAC is often used as a supplement to treat respiratory conditions such as bronchitis and chronic obstructive pulmonary disease (COPD). NAC is typically taken in the form of capsules or tablets, and the recommended dose depends on the individual. However, side effects are rare and generally mild, making NAC a safe and effective option for those seeking to improve their respiratory health.
N Acetyl Cysteine may lower blood pressure
One of these is its ability to lower blood pressure. A review of several studies found that N-acetyl cysteine was effective at reducing blood pressure in people with hypertension. In one study, participants who took N-acetyl cysteine had an average reduction in systolic blood pressure of 9.5 mmHg, compared to those who took a placebo. Other studies have shown similar results, suggesting that N-acetyl cysteine may be an effective treatment for high blood pressure. While more research is needed to confirm these findings, N-acetyl cysteine may offer a safe and natural way to lower blood pressure.
N Acetyl Cysteine may help blood clots - thrombosis
Blood clots are a necessary part of the body's natural healing process. They help to stop bleeding by sealing off damaged blood vessels. However, sometimes blood clots can form in healthy blood vessels, causing a potentially deadly condition called thrombosis. N Acetyl Cysteine is a compound that helps to break up blood clots and prevent thrombosis. It works by preventing the formation of a protein that is essential for clotting. In addition, N Acetyl Cysteine helps to improve the flexibility of blood vessels, making them less likely to rupture. As a result, this compound may help to reduce the risk of thrombosis and improve overall cardiovascular health.
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Date:
October 01, 2020 02:49 PM
Daily Energy is from Thyroid support
Ashwagandha helps the body feel more energized through normalized thyroid activity. This herb can boost thyroid hormones T3 and T4 by normalizing the thyroid stimulation hormone (TSH) in as little as 8 weeks.
Bolster Stamina and Endurance
Keeping fit means getting as much out of a workout as one can. Ashwagandha can improve the performance in any workout setting. Cyclists in an 8 week study showed there maximum aerobic capacity the rate at which oxygen is taken up by red blood cells, and respiratory exchange, how much oxygen can be inhaled and carbon dioxide is exhaled. Cyclists found improvement compared to the placebo group studied.
Focus, sharpness, concentration, protect your mind
Adaptogens can help the body adapt to stress, improve energy, and assist the brain in staying more mentally focused. Ashwagandha can protect brain cells even when sleep deprived. It also increases glutathione levels a key antioxidant needed by the liver. One study showed that ashwagandha can slow the decline of memory and mental function in elderly people. An 8 week study showed that this herb can improve working memory and reaction time.
Looking to Improve Memory, Stamina, Endurance, concentration, and energy, give ashwagandha a try for 8 weeks and see the difference.
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Date:
May 15, 2019 02:07 PM
Curcumin has been known to be a silver bullet. It can be used to cure a host of diseases and conditions including cardiovascular diseases, Alzheimer’s, and cancer. Now depression can be added to the list according to new research. The Centers for Disease Control (CDC) notes that depression affects 16 million Americans every year. Although treatment for it is available, it usually comes with adverse effects. Therefore, there is compelling need for a safer means of treating people. Before this study, it has already been found from multiple studies that curcumin can have an effect on depressive conditions. It was reported to be well tolerated by patients with no adverse side effects. For their current study in Australia, the researchers looked at twenty years of data including current studies on curcumin. They then studied about 342 patients using curcumin and a placebo. From their results, there was a significant reduction in depression after treatment with curcumin compared with the placebo after six weeks of treatment. The researchers then concluded that compelling evidence exists for the use of curcumin in treatment of depression. Key Takeaways: "The study also found that curcumin exhibited significant anti-anxiety properties, based on data from 377 patients." Read more: https://www.naturalnews.com/2019-04-11-curcumin-seen-to-be-one-of-the-best-natural-ways-to-alleviate-depression.html Depression has been linked to inflammation, consider trying CBD to boost mood, reduce anxiety, and reduce inflammation.
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Date:
May 10, 2019 02:17 PM
Scientific literature on how marijuana works on the body is rapidly expanding. Right now, there are a plethora of studies on how marijuana works on the human brain. Some studies have shown that it can be effective in treating disorders of the brain like epilepsy. Recent tests show that marijuana can increase the risk of dementia because it restricts the flow of blood to the brain. These brain areas are essential for memory development. The area most affected is the hippocampus which can result in Alzheimer’s if prolonged. The researchers for the study used single photo emission computed tomography (SPECT) to measure blood flow to the brain after taking marijuana and they reported that there were very low and abnormal blood flow levels observed. This is when compared with persons who did not take marijuana. 982 patients were selected from a wide variety of data sources that was available to the researchers concerning persons who previously used or were still using marijuana. The results of the study showed that persons taking marijuana were at a risk of dementia due to the low blood flow to their hippocampus. Key Takeaways: "Users were analyzed using a brain SPECT and by conducting mental concentration tests against a sample of 100 people who had not used marijuana to determine whether there were significant differences that arose between users and non-users of cannabis." Read more: https://www.naturalnews.com/2019-04-19-marijuana-lowers-blood-flow-to-the-brain-may-be-useful-for-epileptics.html
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Date:
May 09, 2019 02:09 PM
A new study has found that adding fermented shiitake mushroom to rice bran is effective in inhibiting the growth of Salmonella typhimurium. The study was conducted on mouse organs and it was published in the journal BMC Complementary and Alternative Medicine. This formulation has been hailed as a new antimicrobial food-compatible formulation. The study was conducted on murine macrophage cells and in mice. Before this, it was known that the bioactive compounds in rice brans and in shiitake mushrooms have a lot of potential health benefits in mice, cells, and rodents. When the mycelia cells were compared against non-fermented ones, it was found that the bioactive compounds present in the fermented shiitake mushrooms could not be found in the ones that had not fermented. Further findings showed that the pathogen, Salmonella, was inhibited in infected macrophage cells and in organs in the mouse such as the cecum, mesenteric lymph node, spleen, and the liver. Another finding was that there was increased secretion of the bacteria in the feces in mouse. Overall, this findings show that fermented shiitake mushrooms with rice brans can be used as an antibiotic and antimicrobial food. Key Takeaways: "A study published in the journal BMC Complementary and Alternative Medicine found that a formulation of fermented shiitake mushroom with added rice bran can inhibit the growth of Salmonella typhimurium in infected mouse organs." Read more: https://www.naturalnews.com/2019-04-16-shiitake-mushrooms-are-a-powerful-medicinal-superfood.html
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Date:
May 08, 2019 04:35 PM
Chemotherapy which is often shortened to chemo is the use of drugs to eliminate and reduce cancer cells. Because of its systemic effects and ability to kill cancer cells despite the site they are found, it has been widely used in conventional medicine and oncology to fight cancer. But the treatment is not without risks since it can include long term damage to sensitive organs in the body like the lungs, heart, and kidneys. A recent study that was published in the American Journal of Chinese Medicine took a look at the effect of chemotherapy on the kidneys. They studied the effectiveness of safflower seeds against the side effects of cisplatin, a chemotherapy drug used against cancer. They used animal models and compared the effect on damages to the kidneys. Cisplatin is not only used to treat cancer, it is used to prevent the spread of cancer to other parts of the body. It has some side effects which include nausea, vomiting, hair loss, dry skin, and hiccups. It is advisable that pregnant women and breastfeeding women not take it because it can harm the baby. When safflower seeds effect were studied, there were remarkable results discovered leading to the conclusion that safflower seeds were effective in reducing the effects of renal damage caused by cisplatin. Key Takeaways: "The treatment, despite being touted as “effective against many forms of cancer,” isn’t without risk, which can include both acute and long-term damage to organs like the lungs, heart, nerves, and kidneys." Read more: https://www.naturalnews.com/2019-04-17-reduce-the-effects-of-chemotherapy-with-safflower-seeds.html
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Date:
May 06, 2019 03:42 PM
Phytotherapy Research recently published new South Korean research indicating the effectiveness of red ginseng extract against acne symptoms. They studied red ginseng ethanol extract and found that it exhibits comparable anti-microbial properties to those of the most common antibiotic acne medications. Red ginseng has been prized throughout Asia for its medicinal properties for many years. It also has other effects that can help fight acne, including boosting the immune system and improving sleep quality and endocrine balance throughout the body. Key Takeaways: "They found that red ginseng ethanol extract exhibited similar, if not even better, antimicrobial activity against Propionibacterium acnes compared to benzoyl peroxide or azelaic acid." Read more: https://www.naturalnews.com/2019-03-21-red-ginseng-a-great-natural-cure-for-acne.html
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Date:
May 06, 2019 03:16 PM
Commercial food industries have long used artificial colors to enhance the look of their products. With consumers now trending toward wanting more natural ingredients in their food and beverages, natural colors attained from plants is an easy solution. For example, the anthocyanins, which give grape skins their various colors, can be used to make colas several different colors. They also have a beneficial health component, as they contain anti oxidants that are know to aid in several areas of health and nutritional balance. Key Takeaways: "Anthocyanins from grape skins can be used as a safe and natural food colorant, according to a study published in the Journal of Food Processing and Preservation." Read more: https://www.naturalnews.com/2019-03-29-anthocyanins-from-grape-skins-could-potentially-be-used-a-colorant.html
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Date:
May 03, 2019 03:55 PM
A team from the University California, Davis recently completed a study to see what impact turmeric-containing herbal supplements have on sebum production or transepidermal water loss, and to compare this with the effects of pure turmeric supplements. The 28 volunteers who completed the full test took the turmeric-containing herbal supplement, a supplement with only turmeric, or a placebo for four weeks. While none of the treatments impacted sebum production of the skin, the turmeric-containing supplement did reduce transepidermal water loss, which suggests that it improves the skin’s barrier function. Key Takeaways: "A study published in the Journal of Medicinal Food reported that turmeric-containing herbal supplements can be used to improve skin barrier function." Read more: https://www.naturalnews.com/2019-03-29-comparing-the-effects-of-turmeric-and-turmeric-containing-herbal-tablets-on-skin-barrier-function.html
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Date:
April 30, 2019 04:16 PM
According to a South Korean study published in Phytotherapy Research, red ginseng can be an effective treatment for acne in place of traditional medications with potential negative side effects. In fact, red ginseng performed as good or better than benzoyl peroxide in terms of its effectiveness against fighting acne. Specifically, redness symptoms were significantly reduced with the use of red ginseng. The study concluded that the participants acne improved because of panaxynol and panaxydol, the active ingredients in red ginseng. Key Takeaways: "They recruited 20 participants and treated them with cream that contains 3 milligrams per gram (mg/g) of red ginseng ethanol extract for four weeks." Read more: https://www.naturalnews.com/2019-03-12-red-ginseng-is-a-natural-cure-for-acne.html
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Date:
April 29, 2019 05:04 PM
Fatty liver disease is something that many people struggle with and fear in their lifetimes. Because it is nonalcoholic, it is difficult to rationalize having the disease as it is not intentionally done. Many professionals have attempted to lessen the ability to get the disease, and there is a medication that helps to put a stop to the disease. The medicine is called CoQ10 and it is very effective at halting inflammation in and around the liver. Key Takeaways: "Those receiving the CoQ10 supplement showed better markers overall after the study period was completed as compared with the placebo group." Read more: https://www.naturalhealth365.com/fatty-liver-disease-coq10-2789.html
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Date:
April 27, 2019 09:55 AM
According to six separate studies published in the Asia Pacific Journal of Clinical Nutrition, the regular consumption of fatty acids substantially decreases the risk of premature death in adults. When the fatty acids are derived specifically from fish oil, the risk of death from any cause is reduced by 14 percent, compared to low or no consumption. Specifically, the risk of dying from a cardiac event is reduced by a whopping 47 percent. Unfortunately, because these studies don't appear in medical journals, most doctors do not advise their patients to take fish oil. There is also evidence that suggests fish oil decreases the risk of stroke and has potent anti-inflammatory properties. A word of caution, if you are on blood-thinners, consult with an integrative physician before taking fish oils regularly. Key Takeaways: "In one study, fish oil was associated with better survival rates in heart attack victims, with researchers finding improved heart function and lower levels of inflammatory markers in people who took high-dose fish oil for six months after suffering a heart attack." Read more: https://www.naturalhealth365.com/fatty-acids-nutrition-news-2790.html
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Date:
April 23, 2019 01:53 PM
According to over 12,000 peer-reviewed studies, the herb curcumin has over 800 preventive and therapeutic uses. It is estimated that the health-enhancing properties of this powerful herb can replace 14 pharmaceutical drugs with no negative side effects. Research published in the journal Biochemistry and Biophysical Research Community shows that curcumin is up to 100,000 times more effective than the diabetes drug Metformin in activating AMPK, which is used to increase glucose uptake. In addition, a 2008 study revealed that curcumin is just as effective as Lipitor in decreasing oxidative stress and inflammation. Research also shows that curcumin compares favorably to Prozac in treating depression without any of the side effects, such as suicidal ideation, tremors, and headaches. Key Takeaways: "Researchers believe it works on depression by inhibiting monoamine oxidase, the enzyme that has been linked to depression when it’s present in high amounts in the brain. It also raises levels of calmness-inducing serotonin and dopamine." Read more: https://www.naturalnews.com/2019-03-07-turmeric-is-just-as-effective-as-14-pharma-drugs.html
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Date:
April 22, 2019 04:18 PM
A recent study published in the British Journal of Nutrition analyzed the diets of more than 2,000 men. It specifically sought to find a correlation between protein sources and diabetes. It found that, in general, men with a higher intake of protein from plants were less likely to develop Type 2 diabetes. Conversely, men who got most of their protein from processed or unprocessed meats were more likely to develop Type 2 diabetes. Several other studies from Harvard have reached parallel conclusions. Key Takeaways: "According to the study, men who had the highest intake of plant proteins were 35 percent less likely to develop Type 2 diabetes compared with those who had the lowest consumption." Read more: https://www.naturalnews.com/2019-02-17-plant-proteins-found-to-help-prevent-type-2-diabetes.html
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Date:
April 13, 2019 11:16 AM
Scientists from the University of California, San Diego have performed new research indicating that cannabis/marijuana may be highly effective at relieving the pain caused by diabetic neuropathy. The research found that cannabis compounds are an excellent match for the cannabinoid receptors found throughout the human nervous system, and on inflammatory cells. Patients who received cannabis vapors or cannabis smoke in the study reported drastically reduced pain from their neuropathy. More research is needed to fully explore these effects, to include wider use of placebos and a wider range of different dosage arrangements. Key Takeaways: "A team of researchers from the University of California, San Diego deserves the credit for finding that cannabis has an amazing ability to greatly reduce, and in some cases completely eliminate, diabetic neuropathy pain – and all without the need for dangerous and typically ineffective pharmaceutical drugs." Read more: https://www.naturalnews.com/2019-02-13-cannabis-found-to-reduce-diabetic-neuropathy-pain.html
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Date:
March 28, 2019 05:13 PM
Over 7.5 million Americans suffer from Psoriasis, and researchers in Iraq have taken it upon themselves to spot any potential nutrient deficiencies associated with the condition. Physicians took blood samples from Iranian participants, and they surprisingly found that those who had a psoriasis diagnosis were shown to have insufficient levels of vitamin D. These levels were so insufficient, that they were actually 60% less than that of an individual with healthy levels of vitamin B. Key Takeaways: "The team found that vitamin D levels in those with psoriasis were at least 60 percent lower than healthy individuals. Similarly, zinc levels of people with psoriasis were lower by a third, compared to those who do not have the condition." Read more: https://www.naturalnews.com/2019-01-27-treat-psoriasis-naturally-with-vitamin-d-and-zinc.html
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Date:
March 26, 2019 01:45 PM
If you haven’t yet heard, turmeric is the latest super herb that is as effective as at least 14 drugs and is safe to consume in food, as a tea, or in supplement form. A 2008 study in Drugs found that turmeric worked just as well as Lipitor in decreasing blood levels of cholesterol. Another study in Phytotherapy Research found turmeric to be as effective as steroids in the treatment of chronic inflammatory eye disease. Studies conducted over the past twenty years also show turmeric to be a promising alternative to aspirin, ibuprofen, naproxen, and tamoxifen for its anti-inflammatory and tumor suppressing properties. Key Takeaways: "Have you heard of turmeric but weren’t sure if you should start incorporating it into your lifestyle?" Read more: https://www.healthnutnews.com/science-confirms-turmeric-as-effective-as-14-drugs/
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Date:
February 15, 2019 10:25 AM
Blood pressure, that one health problem you always hear about but really don’t have that much knowledge on. In a new study, research published by the journal of hypertension shows that black seed may be a potential aid in helping lower that blood pressure. The article reviews the basics of the study and provides you with uses and common ways to find black seed. It additionally provides you with a few extra foods that can help lower your blood pressure overall. Key Takeaways: "Ten of these RCTs compared black seed with placebo and one compared black seed with standard treatment. They also looked at the associations between blood pressure reduction and the duration of treatment, dosage of black seed, and type of black seed." Read more: https://www.naturalnews.com/2019-02-10-systematic-review-studies-the-potential-of-black-seed-in-lowering-blood-pressure.html
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Date:
January 25, 2019 10:22 AM
Despite the prevalence of depression, drug companies have still failed to come up with a way to address without side effects. The compound curcumin found in the turmeric spice has already been proven popular for it’s health effects but also holds promise in fighting depression. Phytotherapy Research found that it compared well next to Prozac when reducing depression symptoms. Importantly, taking curcumin does not produce the side effects that Prozac creates. To get more of this into your diet, you can purchase organic turmeric root and add to your meals. It is common to add to meats, cereal, granola, eggs, even coffee and tea. With 12.7% of Americans taking antidepressants, using this natural remedy may be a great option. Key Takeaways: "Lots of people think they either have to live with their negative feelings or accept the possibly deadly side effects that come with antidepressant use, but there are some natural remedies that can be surprisingly effective – and one of the best may prove to be curcumin." Read more: https://www.naturalnews.com/2019-01-22-happy-news-curcumin-outperforms-prozac-reducing-symptoms-of-depression.html
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Date:
January 10, 2019 04:26 PM
Did you know that over 50 pounds of fructose is consumed annually each year by the average individual? Many people are unaware that this fructose can lead to an addiction that is just as strong as alcoholism. In fact, the Journal of the American Dietetic Association specifically found that there are similar social and metabolic components when you compare alcoholism to someone with an addiction to fructose. This shows just how dangerous everyday exposure to the artificial additive can be. Key Takeaways: "Sweets are well-loved by millions of people across the world, with at least 50 pounds of processed fructose being consumed per year." Read more: https://www.naturalnews.com/2018-12-21-industrially-processed-fructose-as-addictive-as-alcohol-morphine.html
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Date:
January 05, 2019 11:15 AM
Foods that are rich in omega-3 fatty acids are showing promise in the reduction of inflammation and arthritic pain. A study was done where 167 adults who suffered from knee pain were given blood tests in order to evaluate where their levels of omega-3 fatty acids were. Those who had less omega-3 compared to omega-6 were the participants that had the most bothersome symptoms. Omega-6 differs from omega-3 in the fact that these polyunsaturated fatty acids are detrimental to health due to inflammatory responses that they induce. Key Takeaways: "Making simple dietary changes can greatly improve your health. Eating more foods rich in omega-3 fatty acids and fewer foods high in omega-6 fatty acids can reduce inflammation and arthritis pain, according to a study published in the Clinical Journal of Pain." Read more: https://www.naturalnews.com/2018-12-20-omega-3-lowers-inflammation.html CBD can reduce inflammation and works in a different way than Omega-3 fish oil.
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Date:
December 21, 2018 08:53 AM
A nutrient called Pyrroloquinoline quinone (PQQ) has shown potential for combating the degenerative neurological symptoms of Alzheimer’s, according to research published by Life Extension. Mice that were given a PQQ supplement developed smaller deposits of toxic proteins in their brains compared to the mice that did not, and also demonstrated better recall, memory, motor skills and learning relative to the control group. Other research suggests PQQ may help with Parkinson’s symptoms, and improve blood circulation within the brain. Key Takeaways: "But there are many ways in which a person can reduce their risk of neurodegeneration as they age, like healthy eating." Read more: https://www.naturalnews.com/2018-12-13-pqq-combats-neurodegeneration-that-can-affect-the-aging-brain.html
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Date:
December 19, 2018 04:39 PM
Tocotrienols, a chemical grouping that belongs to the vitamin E family, has been shown by research to have efficacy in reducing blood sugar levels and inhibiting bone loss. The most recent research came in the form of two studies, both of which made use of a tropical fruit, known as the annato. A pre-diabetic state and osteoporosis was induced in rodent subjects for both of the studies. One of the studies, conducted in Malaysia, showed that the rodent subjects had better parameters for a number of metabolic syndrome indicators, such as fasting blood glucose and triglycerides. In the case of the Malaysian study, the rodents either received a dose of tocotrienols commensurate with normal human supplementation or a diet stripped of tocotrienols. A Texas-based research study compared the tocotrienols with Metformin, a commonly prescribed diabetic medicine. Results showed that the tocotrienols in higher doses was better than the medicine in instituting bone growth. A third study, also in Malaysia, used human subjects with type 2 diabetes. Markers for the human subjects were also improved for the subjects that consumed tocotrienols. Key Takeaways: "Studies have shown that tocotrienols may help inhibit bone loss and regulate blood sugar levels. The tocotrienols used in the studies were derived from the red-orange tropical fruit known as annatto." Read more: https://www.naturalnews.com/2018-11-30-vitamin-e-lessens-bone-loss-risk-due-to-diabetes.html
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Date:
December 12, 2018 09:09 AM
Argan oil is getting a lot of attention in recent years. It is something that is used by a lot of people all over the world. With that being said, there are plenty of countries who do not use it religiously. Some of the benefits of this oil include the moisturizing of your skin and the ability to slow down the aging process for some people. The use of oil is a practice that goes back for many years. Key Takeaways: "One test-tube study applied polyphenolic compounds from argan oil to prostate cancer cells. The extract inhibited cancer cell growth by 50% compared to the control group (14)." Read more: https://www.healthline.com/nutrition/argan-oil
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Date:
October 10, 2018 03:26 PM
It may be hard to believe but beet juice is being considered as a way to improve the living conditions of someone with leg artery disease. Some may wonder how this is even remotely possible. However, reports are saying that people who suffer from this disease feel as if beet juice reduces some of the pain when walking. This is a massive revelation because, if true, now doctors and scientists have a sort of remedy for something they did not have before. Key Takeaways: "“This makes it an attractive potential therapeutic approach for individuals with PAD who have severely limited blood/oxygen supply to the lower limbs which severely reduces their function and makes everyday tasks require a vigorous effort,” said senior study author Jason David Allen of the University of Virginia in Charlottesville." Read more: https://www.reuters.com/article/us-health-blood-vessels-legs/beet-juice-may-reduce-walking-pain-with-leg-artery-disease-idUSKCN1LN2JC?feedType=RSS&feedName=healthNews
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Date:
September 25, 2018 02:01 PM
How does turmeric compare to OTC drugs? Research shows it’s superior in every way Turmeric has earned its reputation as a fantastic natural medicine over the course of thousands of years. Scientists from the University of California at San Diego (UCSD) recently added yet another study confirming the healing properties of curcumin, turmeric’s active ingredient, which they found to have unique anti-cancer properties. Other studies show that turmeric shows great promise in the treatment of depression, diabetes and other serious systemic conditions. Best of all, turmeric has no noticeable side effects! Key Takeaways: "Even in a world awash with prescription medications and over-the-counter pills, Big Pharma’s worst cocktails cannot even begin to touch upon the healing power of turmeric." Read more: https://www.naturalnews.com/2018-09-13-how-does-turmeric-compare-to-otc-drugs-research-shows-its-superior-in-every-way.html
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Date:
September 20, 2018 05:11 PM
A recent American College of Cardiology study of 108 chronic heart failure patients noted that patients with higher omega-3 index levels as a result of oral supplementation appear to suffer less from depression than the control group. Roughly 20 percent of chronic heart failure patients become clinically depressed. The promising results suggest that increased omega-3 index levels may result in better social functioning and reduced cognitive symptoms of depression as measured by the widely-used Hamilton Depression Scale. More research is needed, however, to better understand the impact of omega-3 indexes on depression. Key Takeaways: "A recent pilot study has linked a higher Omega 3 Index with lessened symptoms of depression in a cohort of subjects suffering from chronic heart failure." Read more: https://www.nutraingredients-usa.com/Article/2018/08/22/Higher-omega-3s-status-linked-to-less-depression-in-population-with-heart-failure
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Date:
September 05, 2018 09:52 AM
Although we tend to associate fashion with things like neckties, the truth is scientific ideas go in and out of fashion as well. Various pet theories their have their moment in the sun and then slip quietly below the radar as another more intriguing idea grabs everyone's attention. In the 2000s it was all about genetics and DNA. The Genome project, which would take on the lofty goal of mapping human DNA, thereby aiding scientists in their search to discover the mutations that lead to cancer, or so it was assumed. In actuality the search for causative mutations petered off into almost nothing. Some tumors had no mutations. Nor was there any sort of common DNA factor.
However, it hasn't proven to be a trek back to square one precisely. A Nobel prize winner back in the thirties had a theory that though not conclusive was compelling. This scientist, Warburg, surmised that when the body's mitochondrial cells produced energy as they were supposed to, which is aerobically, the body remains healthy. When energy production became anaerobic, a process that produces lactic acid in the body, then cancer cells would proliferate. To starve these renegade cells, the body would have to re-shift back away from the lactic-acid producing energy style, back to the more positive aerobic method. Some more recent scientists have started to build on Warburg's ideas, even discovering that sugar is a specific for cancer cells, without which they starve. So a best case scenario proposed diet for those with cancer would include high fats, less than fifty percent carbs, and a small amount of protein. Because of the relationship with sugar some diabetes drugs may have secondary use as a way to fight cancer as well. Key Takeaways: "In 1931, Dr. Otto Warburg won the Nobel Prize Physiology or Medicine for his discovery that cancer cells have a fundamentally different energy metabolism compared to healthy cells." Read more: https://www.healthnutnews.com/stop-feeding-cancer-cells-this-is-the-diet-mistake-you-probably-make-that-can-cause-cancer/
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Date:
September 03, 2018 05:53 PM
Many people are told that vitamins are really good for them and the preservation of their health but they do not realize how good they actually are! Vitamins should be an essential part of anyone's diet if they are serious about being healthy. They are great for anyone who is looking to lose weight and to combat potential sicknesses. Overall, many of the things that we are stressed at a young age turn out to be true over time. Key Takeaways: "Three-month-old rats were followed until 14 months of age, with the data indicating that supplementation reduced threshold shifts at the lower and medium frequencies, compared to the control animals. This indicated “an improvement in the auditory thresholds”?, said the researchers." Read more: https://www.nutraingredients-usa.com/Article/2018/08/21/Vitamins-A-C-E-plus-magnesium-may-delay-hearing-impairment-associated-with-age
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Date:
August 13, 2018 12:53 PM
The damiana herb, used historically throughout Central and South America, has proven health benefits -- ranging from reducing depression to aiding in digestion to raising libido. A member of the plant family Turneraceae, Damiana is a small plant with yellow blossoms. It can be smoked or used to make herbal teas, and has been compared to cannabis in its effects. While safe and beneficial in small amounts, Damiana should not be taken in high dosages, as it could result in dangerous changes in blood sugar levels. Key Takeaways: "Some people compare damiana to cannabis due to its relaxing and simultaneously stimulating effects." Read more: https://draxe.com/damiana/
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Date:
July 27, 2018 09:53 AM
Consuming chilled yerba mate can enable humans to burn over 50% more calories than they would without drinking it! This boost in energy expenditure not only relates to more fat loss, but it also helps regulate and improve the cardiovascular system. A study that included 23 participants concluded these findings, showing just how beneficial the consumption of chilled yerba mate is much more useful to the body than simply consuming hot varieties of herbal teas. Key Takeaways: "Data from the study showed that iced yerba mate tea produced over 50 percent more energy expenditure, or calorie burning, versus hot tea, or 8.3 percent compared to 3.7 percent." Read more: https://www.naturalnews.com/2018-06-14-drinking-chilled-yerba-mate-can-help-you-achieve-your-weight-loss-goals.html
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Date:
July 17, 2018 09:54 AM
Honey may be made up of 80% sugar, but that does not take away from its amazing benefits when it comes to cleansing and protecting your skin. Honey can be much more gentle when compared to over-the-counter cleansing products, and it has natural defenses such as antibacterial compounds that cause it to be a great way to avoid potential breakouts. Honey is also full of antioxidants such as polyphenols which will help you avoid any oxidative damage that you may experience. Key Takeaways: "It doesn’t matter what type of skin you have — whether it’s dry, oily, acne-prone, sensitive, inflamed, aging — there’s no one who can’t get better skin with honey." Read more: https://www.thealternativedaily.com/9-reasons-to-start-washing-your-face-with-honey/
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Date:
June 20, 2018 04:44 PM
Humans have what is called a electrochemical system that can be directly impacted by substances referred to as endocannabinoids. One of these is cannabidiol (CBD). CBD oil was given to 30 participants in a 2013 study, and it showed that it helped them successfully reduce the amount of cigarettes that they smoked by 40%. More studies have to be done to determine a direct correlation, but this is good news for those who are continuously struggling to find natural ways to quit. Key Takeaways: "In 2013, a study published in the journal Addictive Behaviors found that smokers who were given a CBD inhaler reduced their cigarette consumption by around 40% compared to those given a placebo." Read more: https://www.healthnutnews.com/cbd-may-help-smokers-quit-cigarettes-finds-new-study/
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Date:
June 01, 2018 05:16 PM
Anthocyanins happen to be a widely discussed antioxidant, more talked about than most. Did you know that anthocyanins are responsible for the color of many of your favorite fruits? They make your blueberries blue and your grapes red. Eating food that is packed with this ingredient can help shield your body from catastrophic issues, like cancer, cardiovascular disease, and even some neurological issues. Additionally, people who eat extra volumes of it have been shown to have lower blood pressure than the average person. Key Takeaways: "Experts believe that most people who eat a varied, healthy diet probably consume nine times the amount of anthocyanins compared to other dietary flavonoids." Read more: https://draxe.com/anthocyanin/
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Date:
May 28, 2018 05:16 PM
A study was recently done in which one half of the participants received fish oil, and the other half received olive oil as a placebo. When the participants were relaxing with a resting heart rate, there didn't seem to be any change between both groups of participants. However, when the group members were put into distressing situations, it was shown that those who had the fish oil had much lower levels of mental stress than those who received the placebo. Key Takeaways: "Participants who took fish oil exhibited blunted heart rate reactivity while they were stressed compared to those who took olive oil." Read more: https://www.naturalnews.com/2018-05-20-how-exactly-does-fish-oil-help-the-heart-counteracts-effects-of-mental-stress.html
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Date:
December 22, 2017 07:59 AM
Schizophrenia can be hard to treat. It causes many troubling symptoms such as visual and auditory hallucinations. It can be very hard to live with these things. Cannabidiol is one of the things which may help. If you are suffering or if a loved one is you should look into this because it can improve quality a life a great deal. The symptoms often make working or being around people difficult so quality of life diminishes. Key Takeaways: "Adjunct treatment with cannabis-derived chemical cannabidiol (CBD) improved symptoms compared with placebo." Read more: https://www.univadis.com/viewarticle/cannabidiol-improves-schizophrenia-symptoms-574419
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Date:
November 16, 2017 07:59 AM
It appears that the article is discussing the benefits and personal use of broth. It seems that it discusses the individual components of broth and how it can be extremely healthy for you in many ways. Uses outside source to back up the writers point and discusses firther the benefits and personal experience with it being used. It then goes into how the cost to benfit ratio is extremely high wich is extremely good compared to other supposed health benefit products. Key Takeaways: "Unlike the astronomical costs of trendy superfoods like coconut oil and avocados, bone broth is cheap to make." Read more: http://www.thegauntlet.ca/drink-bone-broth-for-better-muscle-gain-and-stomach-health/
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Date:
September 05, 2017 04:14 PM
Researchers in Australia have discovered that eating Qunioa can improve heart health by lowering levels of tricylcerides in the blood, a fat linked to heart disease. The study was broken into three groups, individuals who consumed 50G of Quinoa, another consuming 25G of quinoa and another following their normal diet. At the end, the group consuming 50G of quinoa showed a markedly lower level of trigylcerides when compared with the other two groups. Researchers believe that the findings demonstrate that people should eat more quinoa. Key Takeaways: "Whether quinoa is a 'superfood' is still up for debate, but we can now confidently say it does deliver health benefits." Read more: http://www.9news.com.au/health/2017/09/03/03/07/quinoa-is-good-for-heart-say-researchers
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Date:
August 22, 2017 05:14 AM
To vaccinate or not to vaccinate… that is today’s question. You will not find a more polarizing discussion in today’s world. Not even Trump can compare to this question. Parents, grandparents, caregivers, teachers, etc pick one side and one side only. Have you ever tried having a simple educated conversation on this topic? Attacks and attacks only are the product of that debate not doubt. Check out this video for a very interesting point of view. It challenges the notion that immunity can be created by microbes. Think about that for a moment, a totally new way for us to think about immunity. [video mp4="https://www.healthnutnews.com/scientists-children-need-microbes-not-antibiotics-to-develop-immunity/"] Key Takeaways: "While we’ve known for decades that hand washing is important, for some reason, about a decade ago people started freaking out about dirt and started over sanitizing everything."
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Date:
August 16, 2017 04:14 PM
While most are not aware of the health benefits found in activated charcoal, adherents of the ancient Indian medicinal system of Ayurveda understand the true value of this underrated ingredient. Activated charcoal is excellent at soothing the stomach, as it aids digestive health and can alleviate symptoms of bloating. Activated charcoal also provides benefits to the skin as well. Thanks to its powerful cleansing properties, it can clear up even the most stubborn of breakouts. Adherents of Ayurveda also swear by activated charcoal’s superior teeth whitening potential compared to that of traditional fluoride toothpaste. This versatile ingredient also helps to lower cholesterol, can cure a hangover, and act as a natural filter for your water. Key Takeaways: "In other words, activated charcoal can help draw out toxins from your food, water, and body." Read more: https://www.brit.co/unexpected-health-benefits-of-activated-charcoal/
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Date:
August 15, 2017 12:14 PM
Many people in today's modern climate are looking for a new way to destroy and reverse the effects of their unhealthy eating habits. One major thing to look into is how to reverse cholesterol problems. HDL cholesterol is considered the "good" cholesterol, and therefore should be emphasized. One way of doing this that scientists have found, is to eat almonds. In a study, 48 adults had controlled for eating a small amount of almonds, and those that had them were found to return to healthy levels of HDL. Key Takeaways: "Eating almonds on a regular basis may help boost levels of HDL cholesterol while simultaneously improving the way it removes cholesterol from the body, according to researchers." Read more: http://news.psu.edu/story/476734/2017/08/10/research/almonds-may-help-boost-cholesterol-clean-crew
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Date:
August 09, 2017 09:14 AM
This article deals with a study about a substance in marijuana and hemp called CBD. It states that half of the people that used this substance were able to stop taking traditional medicine. It also compares the CBD that comes from the hemp plant to the CBD taken from marijuana. It states the CBD taken from hemp is less expensive but less effective. This article is pro CBD and makes good points in favor of the substance. Key Takeaways: "Users said that the pros of using CBD products were medical relief of their conditions without having the “high” effects caused by THC." Read more: http://gearsofbiz.com/almost-half-of-cannabidiol-users-stop-using-over-the-counter-medicines-survey-says/621
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Date:
July 10, 2017 04:14 PM
When losing weight, you'd think that avoiding fat is the ideal way to accomplish success. However, the truth of the matter is that you need fat to lose weight. Without some fat, you are doing your body a major injustice. Read this article if you'd like more information about the fat that your body needs to help lose weight. What you learn might surprise you but it will also help you achieve great results and the body that you want. Key Takeaways: "Our quality of life is determined by the quality of our thoughts, how we choose to fuel our bodies, and how well we move" Read more: https://www.dmarge.com/2017/07/good-fats-to-eat.html
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Date:
July 10, 2017 12:14 PM
So many people suffer from the excruciating pain of a migraine headache and look for ways they can eliminate the issue from their life once and for all. o far, many people are unable to find such a product. But now, new evidence shed light on cannabis as the cure-all for migraine headaches and those who are suffering from the headaches. What do you need to know about cannabis and migraine headaches? The information is here. Key Takeaways: "New research further validates the efficacy of cannabis in the alleviation of migraine symptoms. Researchers have found that a combination of tetrahydrocannabinol-cannabidiol (THC-CBD) was effective in reducing the severity and number of cluster headaches and migraines compared to prescription medicine" Read more: http://www.naturalnews.com/2017-07-05-is-cannabis-the-cure-all-for-migraines-scientists-think-so.html
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Date:
July 08, 2017 09:14 AM
Proteins are the building blocks of life. Every cell in the human body contains protein. The basic structure of protein is a chain of amino acids. You need protein in your diet to help your body repair cells and make new ones. Protein is also important for growth and development in children, teens, and pregnant women. Amino acids are found in animal sources such as meats, milk, fish, and eggs. They are also found in plant sources such as soy, beans, legumes, nut butters, and some grains (such as wheat germ and quinoa). You do not need to eat animal products to get all the protein you need in your diet. Key Takeaways: "Researchers of the study found that women whose daily calorie intake consisted of 6.5 percent of vegetable protein lowered their risk of experiencing early menopause by 16 percent, compared to women whose daily intake of vegetable protein amounted to only four percent of calories." Read more: http://www.naturalnews.com/2017-07-02-plant-protein-found-to-reduce-reproductive-health-problems-in-women.html
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Date:
July 04, 2017 09:14 AM
People might wonder of there is a difference between fresh or frozen fruits and vegetables. It was believed previously that frozen fruits and veggies do not have as much nutritional value as their fresh counterparts. It was also believed that during freezing, essential vitamins and minerals depleted. There was an article posted at The Guardian's website that stressed today's newer techniques that involve blanching before flash freezing have greatly improved nutrient retention in frozen fruits and veggies. Key Takeaways: "However, an article published in The Guardian‘s website stressed that today’s newer techniques involving blanching prior to flash freezing have significantly improved nutrient retention in frozen fruits and vegetables." Read more: http://www.naturalnews.com/2017-07-01-is-there-a-difference-between-fresh-or-frozen-vegetables.html
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Date:
June 30, 2017 04:14 PM
Growing Medical Marijuana use has been the recent trend, however the FDA has not approved Medical Marijuana for use on pets. Despite this many pet owners are administering Medical Marijuana to their pets to alleviate some of the symptoms and side effects caused by traditional pet medications. Treating a variety of ailments ranging from pain, anxiety seizures and inflammation. Pet lovers would rather use a natural remedy like Medical Marijuana than traditional medications which can be damaging to the liver and kidneys. Key Takeaways: "It would seem that cannabis shows real promise for the safe, natural treatment of pets." Read more: http://www.naturalnews.com/2017-06-26-medical-marijuana-an-instant-hit-for-pet-health.html
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Date:
June 27, 2017 09:14 AM
Canola oil is a popular cooking oil that is attractive to customers and the restaurant industry. Canola oil is believed to have benefits such as a smaller waistline and a cleaner environment. It is now believed that Canola oil may not be as healthy as once thought. Canola oil must undergo many chemical processes in its original form before it can be converted into Canola oil. Also, since the Canola plant is one of the first plants that was genetically modified, it may be subject to exposure by a large amount of pesticides. Key Takeaways: "Even canola oils deemed organic still undergo various production processes, and may not have a healthier fatty acid profile compared with commercial varieties." Read more: http://www.naturalnews.com/2017-06-24-6-reasons-you-should-never-use-canola-oil-even-if-its-organic.html
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Date:
June 26, 2017 09:14 AM
Eggs are all-natural and provide one of the highest quality proteins of any food available. Eggs are super health foods and they have been a breakfast staple from the unknown period of time throughout the world. eggs contain all the daily vitamins and minerals that are needed to produce energy in all the cells of the body. The egg whites are good to have as healthy low diet as compared to the yolk portion. Egg white protein is classified as high quality and valuable protein. Key Takeaways: "Egg whites are very low in calories, have pretty much zero cholesterol, are high in protein and provide amino acids that our bodies cannot produce, making them a great choice for most anyone." Read more: https://draxe.com/egg-white-nutrition/
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Date:
June 24, 2017 12:14 PM
Alzheimer's disease affects nearly 44 million people worldwide. According to a study done by researchers at Temple University in Pennsylvania, olive oil can help preserve memory and essentially prevent Alzheimer's disease. Dominico Pratico, lead researcher of the study, stated that olive oil helps reduce inflammation and activates a process in the brain called autophagy. Autophagy is a way that the cells in the body break down and clean out unwanted debris in the body. Mice were given olive oil in the study, and the mice that received the olive oil showed signs that the olive oil made their memory improve and lessened the signs of Alzheimer's. The researchers from this study plan to continue researching the effects of olive oil and Alzheimer's in older mice to see if they can eradicate the disease in mice altogether. Key Takeaways: "When the team studied the brain tissue from both groups of mice, they noticed "dramatic" differences in nerve cell appearance and function. As compared to the mice that didn't consume the oil, the brain cells of rodents in the oil group showed a dramatic increase in nerve cell autophagy activation." Read more: http://doctor.ndtv.com/news/olive-oil-can-now-help-preserve-memory-and-prevent-alzheimers-1715610
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Date:
June 21, 2017 07:14 AM
Eggs have the potential to contribute to reduced growth stunting around the world.Poor nutrition is a major cause of stunting, along with childhood infections and illnesses.eggs were great food for young children with small stomachs.Eggs contain a combination of nutrients, which we think is important.Children in the treatment group had higher dietary intakes of eggs and reduced intake of sugar-sweetened foods compared to control.They theorized that getting very young children to eat eggs might have an impact. Read more: Researchers find that an egg a day can increase growth in young children
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Date:
June 15, 2017 11:14 AM
Cannabis and kale are both officially super foods but they have different properties which begs the question, which one is healthier? Kale is pack with nutrient vitamins and minerals. Cannabis can be eaten as a vegetable, it has cancer fighting properties as well as anti-inflammatory compounds. When comparing the two, cannabis is richer in nutrients, including protein and has more beneficial properties than those found in eating kale. When compared head to head, cannabis wins. Read more: Cannabis vs. Kale: Which is Better For You?
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Date:
June 12, 2017 07:14 PM
A new health trend called the Mediterranean Diet (MedDiet) involves eating a nearly exclusive combination of fruits, vegetables, grains, and other natural foods, with most fat coming from olive oil. According to a new study, following this diet may decrease one's risk of developing atherosclerotic plaque. Atherosclerotic plaque involves blockage in the arteries, contributing to cardiovascular disease. In the study, participants who adhered most closely to the diet showed decreased plaque levels compared to those who failed to adhere, though the difference was not statistically significant. Read more: MedDiet Protects Against Atherosclerotic Plaque
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Date:
June 10, 2017 04:14 PM
A new study of the Mediterranean diet shows that the reason it is so health is due to the fact it has a high magnesium content. Two universities in China have noted that those who consume this type of diet reduce the risk of heart disease, stroke, and type 2 diabetes. At this point in time it is not possible to rule out other influences. However, based on the size of the analysis, these are very strong findings. Magnesium plays a critical role in more than 300 biological functions, and can help maintain a steady heartbeat. Key Takeaways: "Those who consumed the most dietary magnesium had a 10-percent reduced risk of coronary heart disease, 12-percent reduced risk of stroke and 26-percent reduced risk of type 2 diabetes compared to those who consumed the least." Read more: https://www.oliveoiltimes.com/olive-oil-health-news/high-levels-magnesium-mediterranean-diet-reduce-risk-chronic-disease/54360
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Date:
June 09, 2017 12:14 PM
In the developed world today the most costly medical condition, for youth, is being overweight. This is a symptom arising from over nutrition. One such way to combat this epidemic may be to use probiotic, as part of a regular diet. A double blind test was preformed by the University of Calgary, in Canada. A controlled group of 42 participant age ranging from 7 to 12 years old participated. The participants added a powder mix to daily water intake and were monitored thereafter. The results showed that the group who supplemented with prebiotic lost more weight than those who took the placebo. Since prebiotic is inexpensive and non-invasive this area of weight loss techniques needs to be studied further. Key Takeaways: "Prebiotics reduce body fat in children who are overweight or obese by altering their gut microbiota, according to new research. Prebiotics are non-digestible food ingredients (such as fiber) that act as fertilizers to help stimulate the growth of good bacteria already in the gut, different from probiotics, which introduce new bacteria into the system." Read more: https://www.sciencedaily.com/releases/2017/06/170607123949.htm
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Date:
June 06, 2017 11:14 AM
Do you struggle with depression? If you do, there is a new study that suggests probiotics can help relieve symptoms of depression. 64 percent of the people taking probiotics during a six week study had fewer symptoms of depression compared to those not taking it. This study involved looking at the part of the brain that controls mood control. The probiotic also helps people that have psychological issues which are associated with irritable bowel syndrome. Read more: Can probiotics treat depression? This study suggests yes
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Adaptogenic herbs are special! They can help the body with stress, boost immunity, and promote fast recovery from exercise, to mention a few benefits. One of the world's most effective adaptogen is ashwagandha. This ayurvedic herb can: 
