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Search Term: " meabolized "
The Truth About Sugar: How It's Digested, Metabolized, and Why Too Much Can Be Dangerous   
Date:
June 25, 2022 10:13 AM
What is glycation and what does it do to the body? Glycation is a process that occurs when glucose binds to proteins, lipids, or nucleic acids. This can damage tissues and lead to the formation of advanced glycation end products (AGEs). AGEs are toxic compounds that contribute to the development of chronic diseases, such as diabetes, atherosclerosis, and Alzheimer’s disease. The body has mechanisms to prevent glycation, but these become less effective with age. Additionally, certain lifestyle choices, such as smoking and a high-sugar diet, can increase the risk of glycation. Therefore, it is important to be aware of the risks and take steps to protect the body from this damaging process. How does sugar cause glycation? Sugar causes glycation in several ways. First, when sugar is present in the bloodstream, it can attach to proteins and lipids, forming new molecules called advanced glycation end products (AGEs). Once formed, AGEs can accumulate in tissues and cause damage. Second, sugar can also indirectly cause glycation by promoting inflammation. Inflammation triggers a release of immune system chemicals that can damage tissues. Third, sugar can also impair the body's ability to regenerate tissues. This is because glycation damages DNA, making it difficult for cells to divide and multiply properly. over time, this leads to a decrease in the body's ability to heal wounds and repair damaged tissues. As a result, sugar plays a significant role in the development of conditions such as diabetes and Alzheimer's disease. How can you prevent glycation from happening? There are several ways to help prevent glycation from occurring. First, it is important to control blood sugar levels by eating a healthy diet and maintaining a healthy weight. Exercise can also help to regulate blood sugar levels and prevent glycation. In addition, antioxidants may help to protect against glycation by scavenging sugar molecules before they can attach to other molecules. By taking these steps, you can help to prevent glycation and the age-related conditions that are associated with it. Should we be worried about sugar intake? Sugar is a complex topic, and there is still a lot of scientific research to be done in order to understand all of its implications. However, based on the current evidence, it seems that we should be at least somewhat concerned about our sugar intake. Numerous studies have linked sugar consumption to an increased risk of obesity, type 2 diabetes, heart disease, and certain types of cancer. And while sugar itself is not necessarily bad for you, the truth is that most of us consume far more sugar than we need. The average American consumes over 150 pounds of sugar every year, which is well above the recommended limit. So, while you don't need to eliminating sugar entirely from your diet, it is important to be aware of how much sugar you're consuming and to make sure that you're not overdoing it. What are some healthy alternatives to sugar? Sugar is a common ingredient in many processed foods, and it can be difficult to avoid. However, consuming too much sugar can lead to weight gain, cavities, and other health problems. Thankfully, there are a few healthy alternatives that can be used in place of sugar. Stevia is a popular choice, as it is derived from a plant, has no calories, and does not elevate blood sugar levels. Xylitol and erythritol are both sugar alcohols that have a lower calorie content than sugar and do not cause cavities. These substitutes can be found in most supermarkets, and they can help to make healthier choices when it comes to sweetening food and drink. So, while you don't need to eliminating sugar entirely from your diet, it is important to be aware of how much sugar you're consuming and to make sure that you're not overdoing it. There are a few healthy alternatives that can be used in place of sugar. Stevia is a popular choice, as it is derived from a plant, has no calories, and does not elevate blood sugar levels. Xylitol and erythritol are both sugar alcohols that have a lower calorie content than sugar and do not cause cavities. Our suggestion is Kal brand Stevia, it is a no after taste stevia with over 1800 servings, this is VitaNet's Recommendation. Try a sugar alternative in your next recipe and see how it tastes! You might be surprised at how good it can be.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6413) How DIM Complex Supports Hormone Balance and Liver Function for Women of All Ages 
Date:
April 23, 2022 10:34 AM
Hormones are chemical messengers that help to regulate various bodily functions, including metabolism, growth, reproduction, and mood. When hormones are out of balance, it can lead to a variety of problems, including fatigue, weight gain, anxiety, and depression. There are many different factors that can contribute to hormone imbalance, including stress, diet, and certain health conditions. Luckily, there are also many things that you can do to help keep your hormones in check. Exercise, for example, has been shown to help reduce stress and improve sleep quality, both of which are important for maintaining hormone balance. Eating a healthy diet is also important, as certain nutrients (such as omega-3 fatty acids) have been shown to assist in the regulation of hormones. Millions of women suffer from hormone imbalances, which can lead to a wide variety of health problems. A hormone imbalance can cause many different problems, including weight gain, fatigue, mood swings, and hair loss. DIM Complex is a natural supplement that helps to balance hormones and improve overall health. DIM Complex contains diindolylmethane (DIM), which helps the body to metabolize estrogen and keep it in balance. What is DIM Complex? DIM Complex is a supplement that is derived from cruciferous vegetables. It is available in capsule form and can be taken by mouth. The active ingredient in DIM Complex is diindolylmethane, which is a compound that is found in broccoli, cabbage, and kale. Studies have shown that diindolylmethane has a variety of health benefits, including the ability to reduce the risk of cancer and heart disease. Additionally, diindolylmethane has been shown to improve the metabolism of estrogen in the body, making it an effective treatment for conditions like PCOS and endometriosis. DIM Complex is a safe and effective way to obtain the benefits of diindolylmethane, and it may offer a valuable addition to your overall health regimen. How does it work? It has been shown to improve the metabolism of estrogen in the body, making it an effective treatment for conditions like PCOS and endometriosis. DIM works by inhibiting the production of enzymes that convert testosterone to estradiol, a more potent form of estrogen. This action reduces the amount of estradiol available to bind to receptors in the body, resulting in fewer symptoms of estrogen-related conditions. DIM has also been shown to reduce inflammation and improve insulin sensitivity, both of which are important factors in the management of PCOS. While further research is needed to confirm these effects, DIM appears to be a promising treatment for women with hormone-related conditions. How does diindolylmethane bind up estrogen in the gut? Diindolylmethane (DIM) is thought to have many health benefits, including the ability to bind up estrogen in the gut. The body breaks down estrogen into two main forms: estrone and estradiol. These hormones can then be further metabolized into other active or inactive compounds. One of these inactive metabolites is estrogen sulfate, which is excreted in the feces. DIM is thought to increase the activity of enzymes that convert estrone and estradiol into estrogen sulfate, thereby reducing the amount of active estrogen in the body. This may explain why DIM is often used as a natural treatment for conditions like PCOS and endometriosis, which are characterized by high levels of circulating estrogen. Additionally, DIM may also help to reduce the risk of breast cancer by binding up estrogen in the gut and preventing it from being absorbed into the bloodstream. Who can benefit from taking DIM Complex DIM Complex is a supplement that is said to offer a number of benefits. These include supporting hormone health, helping to clear blemishes, and promoting a healthy weight. However, who can actually benefit from taking this supplement? DIM Complex is most often recommended for women who are going through menopause or perimenopause. This is because it can help to balance hormones and relieve some of the symptoms associated with these changes, such as hot flashes and night sweats. In addition, DIM Complex may also be beneficial for women who are struggling with PCOS or other hormonal imbalances. Some research suggests that it may help to improve insulin sensitivity and reduce inflammation. Finally, DIM Complex may also be helpful for anyone who is struggling with acne. This is because it can help to regulate hormone levels and reduce the production of sebum, which is often responsible for clogged pores. Ultimately, DIM Complex offers a wide range of potential benefits. However, it is most often recommended for women who are experiencing hormone-related issues. Foods that are high in indole-3-carbinol (DIM) Indole-3-carbinol (DIM) is a substance that is found naturally in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. In recent years, DIM has gained attention for its potential health benefits. Some research has suggested that DIM may help to protect against certain types of cancer, and it has also been shown to boost the immune system. Foods that are high in DIM include:
If you're looking to increase your intake of DIM, adding more of these vegetables to your diet is a good place to start. You can also take a DIM supplement, to reduce calories intake and guarantee the amount of DIM your getting into your diet. Quick benefits:
Please consider taking DIM and feel the difference it can make!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6389) How MCT oil supports brain health and improves memory
Date:
March 20, 2019 05:04 PM
MCT oils or Medium-Chain Triglycerides have numerous health benefits. For those with digestive issues, the good news is that they are easily absorbed and metabolized. The body can burn them for fuel as opposed to storing them as fat. They also cause levels of ketones to rise in your blood stream, making them great for weight loss, as a sort of short cut for the keto diet.They help in the development of neurotransmitters so they are great for memory issues. Some recent studies have shown improvement in brain function so they are being studies as a possible route for treatment of cognitive problems such as Alzheimer. Key Takeaways:
"MCTs have been shown to decrease fat and increase lean muscle mass, and MCT oil is currently sold to promote weight loss and improve athletic performance and endurance. MCTs are also routinely administered to prevent muscle wasting in critically ill patients." Read more: https://www.naturalhealth365.com/mct-oil-brain-health-2816.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6085) Green Coffee Bean: Do Benefits Outweigh Risks of This Weight Loss Supplement?
Date:
July 14, 2017 12:14 PM
Anything for weight loss should be used carefully. Losing too much too fast is bad for you, and these supplements often raise the heart rate as well. Green coffee bean has risks like any other supplement. This discusses whether the benefits are greater than these. It will help you decide whether or not you want to use it. If you do you should do so responsibly. Do your own research before using any diet supplement. Key Takeaways:
"This study shows that the major CGA compounds present in green coffee are highly absorbed and metabolized in humans." Read more: https://draxe.com/green-coffee-bean/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4971) Prostate cancer breakthrough: Combination of three plant-based nutrients found to MELT AWAY prostate cancer cells
Date:
July 03, 2017 12:14 PM
A study by the University of Texas, Austin, has found that there is potential for treatment of prostate cancer using compounds found in common foods. ursolic acid, commonly found in apple peel, curcumin, found in the spice tumeric, and resveratrol, found in red grapes. These three compounds were tested together as a new combination approach to creating treatments. Working together, these compounds caused shrinkage of tumor cells and changed the way the cancerous cells metabolized nutrients that allow them to grow out of control. Key Takeaways:
"A fascinating new study published in Precision Oncology has found that a combination of three plant-based nutrients “melts away” prostate cancer cells." Read more: http://www.naturalnews.com/2017-06-30-prostate-cancer-breakthrough-combination-of-three-plant-based-nutrients-found-to-melt-away-prostate-cancer-cells.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4919) Are the MCT Oil Nutrition and Health Claims Backed Up?
Date:
May 13, 2017 08:44 AM
Coconut oil has experienced a huge increase in sales and taken the media bystorm in recent years. coconut oil can be found not only in specialty health food stores, but at most local grocers as well. Diets high in MCTs (65% of coconut oil's makeup) have been shown to improve glucose tolerance and reduce body fat accumulation when compared to diets high in LCTs. MCFAs have also been shown to preserve insulin action in, and insulin resistance in rat studies. When compared with other fats, coconut oil contains 2.6% fewer calories. Keep in mind however that all high-fat foods and oils are calorically dense and simply adding in more calorically dense food to a diet already ample in calories is not likely to result in weight loss.According to the Academy of Nutrition and Dietetics, virgin coconut oil has potential antioxidant properties due to certain plant nutrients it contains called phenolic compounds. Key Takeaways:
"MCT oil is associated with a whole host of health claims including weight loss, decreased risk of metabolic syndrome, lowered abdominal fat, lowered inflammatory markers, decreased triglyceride levels, and the ability to raise HDL (good) cholesterol." Read more: http://www.organicauthority.com/are-the-mct-oil-nutrition-and-health-claims-backed-up/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4603) Turmeric and diabetes
Date:
May 12, 2017 06:44 AM
An April 16th Health Capsule released a report that related that turmeric can trigger insulin secretion, which can modulate blood sugar levels. Health Capsule however, recommended a dose that was too high fir what is needed, recommending 1.5 grams a day in three divided doses. Turmeric is metabolized over 72 hours in the body, hence you might not even need a daily dosage. It's also important to note that besides Curcumin, there have been other essential substances substances contained in turmeric. Read more: Turmeric and diabetes
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4594) Bulletproof coffee - coconut and butter does improve health
Date:
September 23, 2016 02:44 PM
A cup of coffee is a common thing that most of people drink in the morning. However, since many people realized that coconut oil and butter are healthy fats (Axe, 2016), they started replacing cream with them. This coconut and/or butter coffee is known as bulletproof coffee and it is a new trend of healthy morning drink. It has been extremely popular all over the world.
Coconut oil has so many benefits for your body, such as:
· Increases your energy - its ingredient, MCT (Medium Chain Triglycerides), is absorbed by the body and metabolized as fuel more quickly (Tifanny, 2016).
· Improves your immune system - There is a lot of lauric acid in coconut oil that is effective to prevent and cure many viruses (WebMD in Tifanny, 2016).
· Improves brain function – Its fatty acid plays an important role in memory and brain functions (Axe, 2016).
· Promotes heart health – Coconut oil contains good cholesterol that is good for your heart (Axe, 2016).
· Acts as anti-inflammatory – Antioxidant content makes coconut an effective anti-inflammatory food that help reduce arthritis (Axe, 2016).
· Is good for hair and skin – It is able to smoothen and tighten the skin, as well as maintain healthy hair (Axe, 2016).
On the other hand, butter also offers many advantages for your health, such as:
· Prevents and treats many diseases - Omega 3 fatty acids in butter are essential for growth, as well as prevention and treatment of arthritis, coronary artery disease, cancer, inflammation, and high blood pressure (Leonard, 2016).
· Improves your brain, blood circulation, and hormonal system – It helps prevent neurodegenerative and heart diseases, increase energy expenditure, and act as anti-inflammatory (NN, 2014).
· Is good for bones and blood circulation – Butter contains vitamin K that plays an important role in blood clotting and keeping the bones strong (Leonard, 2016).
· Helps with weight loss – It makes you feel full for a longer period and its conjugated linoleic acid (CLA) is an effective aid for losing weight (Leonard, 2016).
· Reduces caffeine sensitivity – Butter fat can protect the stomach from shakes and nausea caused by caffeine (Leonard, 2016).
· Boosts the energy – It provides more sustained energy for the body (Leonard, 2016).
· Accelerates metabolism and digestion – Vitamin A, D, and E contained in butter are easily absorbed by the body and stored in gastrointestinal tract (Axe, 2016).
Based on the facts above, coconut and butter coffee is a healthy drink. However, excessive consumption of this bulletproof coffee is not good. Healthy fats can only function effectively in the body if the amounts taken are mooderate, not more and not less. Moreover, drink this coffee as the replacement of your breakfast is not recommended since it does not have enough essential nutrients (Gunnars, 2016).
References
https://authoritynutrition.com/3-reasons-why-bulletproof-coffee-is-a-bad-idea/
https://draxe.com/healthy-fats/
//nextshark.com/neil-degrasse-tyson-reveals-just-how-broke-you-are-compared-to-bill-gates/
//thecoconutmama.com/coconut-oil-coffee/
//www.naturallivingideas.com/add-butter-to-coffee/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3311) What is chitosan and how effective is it for weight loss?
Date:
August 19, 2015 06:26 PM
Chitosan is a compound extracted from the hard shells of shrimps and other crustaceans. While it has many uses, it also claims that it aids in the elimination of excess fat in our bodies which makes it a perfect candidate for inclusion in any weight loss program. It can be ingested in the form of capsules, powder and pills. How does it work? Chitosan works by preventing the absorption and storage of fat before it is metabolized in the stomach. Basically, it is a fiber that absorbs fats when they enter the body. Therefore, the fat is broken down and does not get absorbed into the blood stream. Instead, fat and chitosan go through your small intestine or the ileum where they bind with bile acids. They then form an insoluble gel that passes through the large intestine and is excreted out of your body. This means that instead of the fat being absorbed into the blood stream, it is excreted out of the body and no fat absorption means no weight gain. There is still another way that chitosan helps in weight loss. Since chitosan is a fiber, it promotes cleansing which is important in the process of losing weight. Another reason this compound seems to work for weight loss is that it makes the body not to crave for fattening foods. It neither starves nor does it make you feel hungry; this is simply because you continue eating fat, the only thing is that the fat does not get absorbed into your blood stream. Now, since less amounts of fat are entering the blood stream, the body is able to burn the existing fat present in your body. Therefore, your body burns the fat in the body and you constantly lose weight.
Chitosan products contain vitamin C which makes it swell up. This promotes appetite suppression which is very important for weight loss. References //www.webmd.com/vitamins-supplements/ingredientmono-625-chitosan.aspx?activeingredientid=625&activeingredientname=chitosan //slism.com/diet/chitosan-weight-loss.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3198) What Can Stevia Do For Me?
Date:
February 08, 2014 09:31 AM
Does that early morning blueberry muffin leave you craving another sweet treat only hours later? Or do you find that you need a candy bar or soda drink in order to make it through the afternoon. If so you are not alone. The unfortunate fact is that many of us have become addicted to sugary treats. This leads us on a roller coaster ride of sugar highs and lows, where we are constantly trying to give our body the energy demands. Not only does this make it difficult for a us to be productive, it also causes health problems and makes it difficult to maintain our weight. There is a natural solution that can help you out – Stevia. Stevia is derived from the leaves of the Stevia plant. It's a natural sweeter which contains no sugar and no calories. People with a sweet tooth also love the fact that stevia is 100 times sweeter than sugar in some cases. Here are some of the benefits of making the switch from sugar to stevia. Protect Your Waistline In 1700 it was estimated that the average person only consumed about 7 pounds of sugar a year. Flash forward to 2014 and the average person is consuming 150 pounds a year. That's 20 times as much sugar! Of that sugar approximately 5% will be used for energy later on, 60% will be metabolized by the body and incredible 35% will be stored as fat so it can be used for energy if required. This is having a huge effect on people's waistline is and is contributing to the massive obesity epidemic which is seen worldwide abysses levels doubled since 1980. Stevia contains no calories but is sweeter than sugar. Even more importantly it does not cause blood sugar levels to rise after it is consumed. Having stable blood sugar levels prevents people from over eating and makes it much easier to maintain a healthy weight. Prevents high blood pressure High blood pressure is often referred to as the silent killer. Often people are unaware that they even suffering from high blood pressure until it is too late. In the United States 67 million American adults have high blood pressure. That's approximately a third of the population. The consequences of this are very severe including increased risk of stroke and heart disease. These are the first and third leading causes of death in the United States. According to the medical website WebMD Stevia can be used to reduce high blood pressure and heart burn.
Bacteria feeds on the sugars that you consume and this in turn creates acids. A little acid can help to control the bacterial environment in your mouth. But if there is too much acid over a prolonged period of time it can cause serious problems for your oral health. These acids can destroy the tooth enamel and lead to tooth decay. Stevia does not feed the bacteria in the mouth in the same way as sugar, so it protects your teeth while still providing you with the same delicious sweet taste. Stevia is a great way for you to enjoy the sweet tastes of the foods that you love without having to worry about your waistline, high blood pressure or destroying your teeth. If you want to satisfy your sweet tooth without damaging your health why not try Stevia? References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3010) ROLE OF BRANCH CHAINED AMINO CIDS IN MUSCLE GROWTH AND ATHLETIC PERFOMANCE
Date:
January 20, 2014 09:06 AM
Amino Acid
Leucine, Isoleucine and Valine are Branched Chained essential Amino Acids(BCAA). These three amino acids account for 35% of the essential amino acids in muscle protein and 40% of the essential amino acids required by humans. Due to their importance, dietary supplementation of these amino acids has become quite common due to their beneficial effects. BCAAs help burn patients to recover faster as the amino acids in high concentration provide the material for the cells to repair themselves at a faster rate. At the same time, BCAAs help in managing diabetes Are very popular due to their many functions in the body of an athlete. This is because unlike other amino acids, it is metabolized in muscle tissue, not in the liver thus it has a more direct effect on the muscles than other amino acids. These functions include:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2974) Impacts of pantethine
Date:
January 09, 2014 04:53 PM
What is Pantethine
Dietary supplementation Pantethine is accessible as a dietary supplement due to proof of its health profits. In different clinical trials of patients with hoisted cholesterol and triglycerides, absolute and LDL cholesterol were diminished by 12%, triglycerides diminished by 18%, and HDL cholesterol was expanded by 9%. These clinical trials were directed with day by day admissions running from 600 to 1200 mg/day. Inside this measurement go there is no proof of a measurements impact relationship, i.e. changes in lipid focuses covered over the reach of measurements. Immediate measurements reaction proof is not accessible in light of the fact that no trial tried more than one measurement. A couple of trials tried 300 mg/day with additional unobtrusive yet factually noteworthy effects. Further deliberately regulated trials of 600 and 900 mg/d dosages have indicated factually huge bringing down of LDL cholesterol in people with extraordinarily or reasonably raised levels of blood lipids. Physiological impacts Two instruments of activity are proposed for pantethine. In the in the first place, pantethine serves as the forerunner for amalgamation of coenzyme A. In the second, pantethine is changed over to two pantetheine particles which are thusly metabolized to structure two pantethenic harsh corrosive and two cysteamine atoms. Cysteamine is conjectured to tie to and therefore inactivate sulfur-holding amino acids in liver catalysts included in the generation of cholesterol and triglycerides.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2956) How Does Creatine Boost Muscle Strength?
Date:
October 28, 2013 11:13 PM
How Does Creatine Boost Muscle Strength?
What Creatine Can Do?
Many young athletes utilize creatine supplements as part of their muscle building routines. Although there have been varied responses to these diet supplements creatine continues to thrive on the market as a sports and health vitamin. Other uses of it include lowering triglycerides in the body as well as homocysteine both of which play a role in heart attacks and strokes. Creatine also promotes better endurance and muscle strength among patients with chronic obstructive pulmonary disease, Parkinson's disease and Muscular Dystrophy. Clinical trials are still under way. Creatine, like all other medications and supplements may cause some adverse effects. It is important that you consult a health service provider or pharmacist before initiating the use of the supplement. The common side effects of Creatine include muscle cramps, weight gain, muscle strain, abdominal discomfort, changes in bowel movements, dizziness as well as liver and kidney dysfunction. This is due to the fact that this protein is metabolized in the liver and the kidney.
Taking Creatine
Creatine should be taken in the recommended dose. Taking more than the recommended dosage can result to severe adverse events such as Rhabdomyolysis which is the medical term for the breakdown of muscles, the components released after massive muscle cell death can damage the kidney and lead to kidney failure. The recommended dose for adults is 2g daily. Using creatine for prolonged periods may eventually lower your body's production of creatine and may lessen its effects. When used judiciously and properly you can benefit from the positive effects of Creatine.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2862) Calcium D-Glucarate And Estrogen And Your Health
Date:
February 16, 2012 11:04 AM
Calcium D-GlucarateCalcium D-Glucarate is a nutrient found in many vegetables and fruits. It is believed that it helps in eliminating the harmful substances from the body and it also helps in lowering the high levels of hormones which includes estrogen, testosterone and progesterone. These effects of the Calcium d-Glucarate protect the body from developing certain types of cancers. Calcium D-Glucarate is found in broccoli, spinach, Brussels sprouts, oranges, apples and grapefruits. Small quantities of this nutrient are naturally made by the human body. Human body carries many toxins that it absorbs from air, food and water. These harmful substances are flushed out of the body by the detoxification process, before it becomes harmful to the body. The body detoxifies itself by conjugation and glucuronidation. The Calcium D-Glucarate helps the body to eliminate toxins and this process is called conjugation. When the D-Glucarate comes in contact with the acidic environment in the stomach, it metabolizes to form an acid called D-glucaric acid and this further metabolizes in the digestive tract into other compounds. The detoxification that takes place with the help of Calcium D-Glucarate is called Glucuronidation. During this process the substance that binds with the toxin is called glucuronic acid. These are processes which occur when the carcinogens, harmful toxins and used hormones are combined with water soluble substances in the liver which helps them to be removed easily from the body. Beta-glucuronidase, an enzyme, breaks the bond between the toxins and the used hormones and helps them to re-circulate into the blood. But Calcium D-Glucarate inhibits this beta-glucuronidase enzyme and supports the vital process of the liver in flushing out the used hormones and toxins. Thus Calcium D-Glucarate acts to block the re-absorption of estrogen and this makes this nutrient a useful estrogen buster. Toxin Flush Calcium D-Glucarate helps the body to flush out used hormones like estrogen, even before they can be reabsorbed into the blood. Higher levels of estrogen are the reason for many types of cancer, the major being breast cancer. D-Glucarate has a role in controlling cancers of the colon, breast and the reproductive organs, as they detoxify carcinogens present in the lungs, breast, liver, colon and skin. It also helps in lowering of the lipid cholesterol levels; serum cholesterol is reduced by 12%, LDL-cholesterol by 28% and triglycerides by 43%. Decrease Estrogen The harmful toxic substances that the body is exposed to, can increase the level of circulating estrogen, in both men and women. This increased level of estrogen disrupts the hormonal balance of the body. So this excess estrogen is metabolized and broken down to be flushed out from the body. Excess of estrogen can cause a condition called 'estrogen dominance,' which causes hormone related disorders in the body. So it is necessary to reduce the estrogen level to save the body from the risk of Fibromyalgia, Uterine fibroid tumors, fibrocystic breasts, Endometriosis and premenstrual syndrome. Estrogen is an essential hormone present in the body but too much of it can cause cellular disruptions. As it is difficult to avoid estrogenic chemicals found in the environment, it becomes necessary to improve the body's natural ability to flush out the excess hormones and harmful toxins. Calcium D-Glucarate helps in this natural removal of excess hormones and harmful toxins.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2580) What Is A Natural Carb Blocker?
Date:
November 05, 2011 01:57 PM
Carbohydrate BlockerThere are so many individuals nowadays who are already overweight because of their natural love for food that are fattening. Overeating has now become a common problem for many individuals hence, has been the primary cause unto why weight problems have become more rampant. Despite how evident the problem is right now, people still find it very difficult to resist food thus, people having weight related problems is still growing in number.Despite the fact that several diets has been formulated that could help you shed off extra pounds, many of these diets do not work for all because people find it so difficult to adhere to a tasteless diet even for just a week. Because not all diets are easy to adhere with, diet pills has been formulated by experts that helps block carbohydrate therefore, will aid you in getting rid of excess body weight. Carb blockers are pills that helps inhibits the absorption of carbohydrates in your system. With the help of carb blockers, carbohydrates are passed out naturally which means that carbohydrates will no longer be metabolized by the body into fat. With this mechanism, build up or accumulation of fats in your body will be greatly reduced. Brown seaweed extract is a notable carb blocker sold in the market today. This particular product is highly effectual and proven to relevantly reduce the absorption of carbohydrates in your body to as much as 82 percent. Weight loss is not the sole benefit of carb blockers because a good and effectual carb blocker also has the capacity of enhancing your metabolic rate which is highly necessary to make reduction of fat a lot faster. Another capacity of carb blockers is that it could significantly reduce appetite hence, will enable you to consume less food that can make you fat. This threefold effect that carb blockers could do for your body will really help you achieve your goals of losing weight. A weight loss of five pounds per week is a guarantee once you follow the recommendations indicated in the product’s label. Because of the fact that there are already so many carb blockers that are sold in the market today, it is very necessary to choose those that are 100 percent natural and those that contains effectual components such as cactus extract, capsicum extract, prickly pear extract and brown seaweed extract. These components have innate properties that could help you lose weight faster. Trying ways and means to make yourself more attractive to the eyes of the public is not bad as long as you will only engage on those modalities that will not bring harm on your body. Make sure that the regimens that you will try are highly safe and effectual. If it involves some risk, better not try the regimen because in the end, it is you who will suffer from the health consequences that the product might bring.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2536) Does Lysine Help with Herpes Breakouts?
Date:
September 30, 2011 02:22 PM
Herpes and Lysine RelationshipFor proteins to be utilized by body cells, they are broken down and metabolized into amino acids. Amino acids are the simple building blocks of protein which can be readily used by the cells of the body. There are 20 amino acids in which the human body uses. Eight of these are considered "essential" amino acids which mean that they are not produced by the body in natural ways but must be supplied through the diet or from the food we eat. One of the essential amino acids is Lysine.
Amino Acid LysineLysine is has been long studied with its benefits on herpes simplex infections. Preliminary results showed that lysine supplementation on a regular basis can effectively inhibit the occurrence of genital herpes and sores related to herpes simplex virus. Scientifically, there are two amino acids which have been discovered to have significant effects on herpes simplex virus, namely lysine and arginine. Lysine is effective in minimizing viral outbreaks and in improving the healing process of such infection. On the other hand, arginine can trigger occurrence of symptoms of the viral infection. The mechanism of action is said to be that lysine greatly inhibit the metabolism of Arginine. Clinical studies on tissues have revealed that arginine is the amino acid which is required by the herpes simplex virus to increase in number and become active. Another use of lysine is that it can be employed as a mild anxiolytic. It has been found to have an effect on serotonin receptor sites on the digestive tract. Also, lysine plays a significant role in the proper growth of the individual and in the production of the chemical compound called carnitine which is a substance responsible for the metabolism of fatty acids into energy form. Carnitine in the blood also greatly helps in lowering blood cholesterol levels. Therefore, the risk of cardiovascular diseases associated with high cholesterol levels will be lessened. Another health benefit of lysine is that it can positively influence the absorption of the mineral calcium. As we know for a fact, calcium plays an important role in bone mineralization and maintaining its health and strength. Calcium is also required in the contraction of muscles such as that of the heart. Lastly, lysine is also required in the production of collagen. This chemical substance is necessary for bone and tissue growth and repair.
Lysine DeficiencyDeficiency of this amino acid will provide a feeling of nausea, dizziness, appetite loss, fatigue and stunted growth. Lysine can be obtained from the food we eat. Fish, especially sardines and cod, chicken, beef, lamb, eggs, milk and milk products like cheese and dairy and several fruits and vegetables contain high concentration of Lysine. The fruits rich in lysine include avocados, mangos, apples, papaya, pears and tomatoes. On the other hand, vegetables which have an abundant amount of lysine include legumes such as peas and beans. While some people needs more amount of lysine supply, health experts have formulated concentrated levels of lysine in the form of supplements. Lysine supplements are available in the form of tablets, capsules, creams and suspensions. Also, Red marine algae may help relieve the outbreak as well.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2469) What is the Difference between 5-HTP and Tryptophan And How Does It Help Sleep Patterns?
Date:
June 22, 2011 11:00 AM
5-Htp and Tryptophan to Sleep Better, Feel Better5-HTP, short for 5-hydroxytryptophan, is an organic compound that naturally occurs in the human body. It is a metabolite of tryptophan, and as such it serves as a chemical intermediate in the synthesis of the neurotransmitters serotonin and melatonin. It is sold over the counter in many countries primarily as a dietary supplement. In addition, it is used as an antidepressant, appetite suppressant, and sleep aid. Tryptophan to 5-HTP Tryptophan is best known as an essential amino acid that must be obtained from the diet. Popular sources of this amino acid are eggs, cheese, pork, turkey, chicken, beef, salmon, and white flour. In one metabolic pathway, tryptophan is processed into vitamin B3, or niacin. In a completely different pathway, it is metabolized into serotonin and then melatonin, both of which are processed from 5-HTP. Also known as oxitriptan, 5-HTP has been the subject of numerous studies in the past few decades. Being the immediate precursor of serotonin, regular intake has been observed to specifically increase the production of serotonin, the reason why it has been a very important amino acid widely utilized in the treatment of depression. On the other hand, tryptophan is utilized by the body in many ways. 5-HTP to Serotonin Supplementation of tryptophan has also been used as a therapeutic treatment for depression. It is an alternative to antidepressants and stimulants, especially for patients deemed unresponsive to conventional treatments. Regular intake of this amino acid is recommended for the sole purpose of raising the levels of serotonin. But in order to do so, tryptophan must be metabolized into 5-HTP first. Serotonin is often referred to as the happiness hormone, inasmuch as this neurotransmitter is implicated in several chemical reactions that contribute to physical well-being. For example, the perception of hunger is triggered by low serotonin levels. Not surprisingly, serotonin is the target of many drugs, such as antidepressant, anxiolytic, antiemetic, anti-migraine, and antipsychotic drugs. Serotonin to Melatonin It is a widely accepted fact that serotonin produced and released outside the central nervous system does not cross the blood-brain barrier, and thus it does not have the effect of serotonin found in the brain. That being said, its precursors, tryptophan and 5-HTP, can. For this reason, tryptophan and 5-HTP makes a viable candidate in increasing the levels of serotonin in the central nervous system. Melatonin is synthesized from serotonin by a short metabolic pathway that stems from the synthesis of 5-HTP. Proponents argue that 5-HTP supplements work better than tryptophan due to the fact that the former is the immediate precursor of the neurotransmitters of concern. Furthermore, 5-HTP readily crosses the blood-brain barrier whereas tryptophan is subject to different metabolic pathways. 5-HTP works as an appetite suppressant since it makes serotonin more available outside the nervous system, especially in the digestive tract. By so doing, it promotes the synthesis of melatonin, which induces sleep. It also makes a reliable antidepressant as it increases serotonin levels in the central nervous system. Grab Some Tryptophan or 5-HTP today and feel better, sleep better right now!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2346) What is Bioperine and How Does It Help with Absorption of Vitamins
Date:
April 21, 2011 03:14 PM
Get more from your food with Bioperine.Bioperine is a patented form of an alkaloid found in black pepper. It is derived entirely from piperine, an organic compound responsible for the spicy taste of black pepper and long pepper. Piperine has been noted for its thermogenic properties believed to speed up the absorption metabolism of digested foods. Recent studies have discovered that it also interferes with the release of enzymes that govern the bioavailability of drugs and supplements. By so doing, it enhances the rate of absorption of vitamins. The human body has a complex mechanism of controlling the substances that get in and out of systemic circulation. The first pass occurs in the alimentary canal, where gastrointestinal enzymes break down substances into smaller compounds. It is believed that a very small percentage manages to undergo intestinal absorption after digestion. In general, this is the part where constituents of supplements remain undigested and instead enter the colon together with waste materials. The liver plays a central role to the metabolism of drugs and most bioactive compounds. The compounds that pass the intestinal walls and enter the hepatic portal system, a group of veins that direct blood and other compounds from the gastrointestinal tract to the liver, is further metabolized inside the liver. Anything that the body considers foreign is sent to the kidneys and easily excreted through the urine. This is the reason why bioavailability is significantly reduced after ingestion. Counteracts Effects of Enzymes Bioperine is the only compound known to interact with enzymes that controls the metabolism of foreign materials within the intestinal epithelium. P-glycoprotein is released in the digestive tract to deal with drugs and xenobiotics found in our diet. Vitamins are no exception to the tightly regulated process of absorption in the intestines. These enzymes transport digested compounds to the liver. It has been observed that piperine appears to reduce the expression of p-glycoprotein in the alimentary canal and other parts of the body. Proponents believe that bioperine, a purer form of piperine, is capable of counteracting the effects of the enzyme within the intestinal epithelium, making it easier for vitamins and supplements to enter the hepatic portal system. Increases the Rate of Metabolism Not all compounds that undergo the first-pass effect interact with the cells and tissues they are supposed to act on. If they should have an effect on any cell, they are still subjected to the actions of enzymes specialized for the expulsion of xenobiotics found in the systemic circulation and the rest of the body. For example, CYP3A4 removes foreign materials from the cells and facilitates their excretion. Bioperine is touted to induce thermogenesis and stimulate cellular activities. By so doing, the effects of bioactive compounds are achieved while they remain inside the cells and tissues. The thermogenic properties of bioperine influence the rate of metabolism of digested compounds, including vitamins, minerals, and components of herbal preparations. Note that it can increase the update or prescription medications as well, so caution should be observed when consuming bioperine with medications. If you want to give your body a nutrient boost, add bioperine to your supplement regiment to boost absorption.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2280) Can N-Acetyl Cysteine Boost Liver Health And Function?
Date:
February 10, 2011 12:31 PM
N-Acetyl Cysteine (NAC) And The LiverN-Acetyl Cysteine or NAC is an antidote for poisonous effects of paracetamol overdose. It targets the cells in the liver, raising their capacity to deal with harmful metabolites. There are a number of researches well underway that scrutinizes a variety of medical conditions for which this compound could be of use. It is a known precursor of antioxidants and in itself a scavenger of peroxides and free radicals. Hepatocytes are the cells that take on most of the functions of the liver and account for more than 70 per cent of the liver’s total mass. These cells are responsible for the presystematic metabolism of drugs, also known as the first-pass effect, rendering most drugs innocuous before they are released into the bloodstream. The total amounts of bioactive substances that are distributed to the rest of the body are also largely regulated by hepatocytes, notably carbohydrates. In addition, they are involved in the biosynthesis of protein, cholesterol, phospholipids, and bile salts as well as the functional reserves for protein. Hepatocytes and Toxins Certain drugs produce toxins when broken down by hepatocytes. A classic example is the metabolism of ethanol into acetaldehyde, which is a toxic compound, a probable carcinogen, and an air pollutant emitted by combustion of cars and tobacco smoking. While hepatocytes are known for their detoxifying responses to toxic substances entering the body, the metabolism of toxins actually takes up a great deal of time, resulting in certain toxins getting released into the bloodstream prior to first-pass effect. That being said, continued exposure to toxins wears down hepatocytes, and high concentrations of what we refer to as poisons is certain to bring damage to the liver. This is what happens during overdose of paracetamol, or acetaminophen. In an effort to metabolized excessive amounts of the drug, the liver cells produce by-products that are essentially poisons, which under normal circumstances can be contained well.
NAC and Glutathione ProductionThe major antioxidant synthesized by the human body called glutathione comes to the liver’s defense when toxic by-products are produced. Hepatocytes in particular are so dependent on glutathione in the quenching of toxins that it has been observed that any challenge to the manufacture of this endogenous antioxidant will ultimately result in liver failure. Glutathione is released by hepatocytes in large amounts especially during the metabolism of alcohol and drugs, but during overdose the ravaging activities of ethanol or drug metabolites overwhelm the detoxifying effects of antioxidant reserves in the body. Simply put, the defense mechanisms in the employ of the body have limits. NAC resolves this problem. The presence of NAC in the body augments the liver’s ability to produce the needed amounts of glutathione to effectively counter the harmful properties of invasive substances. In fact, the liver completely recuperates in a matter of weeks even after life-threatening conditions given that NAC is introduced in the human body in time to avoid subsequent damages to other vital organs. Indeed its application has proven to save lives in fatal cases of paracetamol poisoning. N-Acetyl Cysteine is available at your local or internet vitamin store in capsule or tablet forms. Always choose name brands like Source Naturals to ensure quality and purity of the product you buy for better liver health. Have you had your NAC today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2235) You can protect your liver and more with Milk thistle Extract
Date:
December 23, 2010 09:48 PM
Milk Thistle Benefits
Milk thistle also helps to reduce the cholesterol content of the blood and to improve the generation of glutathione, the body's master-antioxidant. Many studies have shown that milk thistle enables patients to survive longer after life-threatening liver conditions such as cirrhosis, and also protects it from the effects of sustained use of common drugs such as acetaminophen (Tylenol and Paracetamol) that progressively damages liver cells, and also of many antipsychotics and antibiotics that have a similar effect. There are no doubts that taking milk thistle does your liver a great deal of good and leaves it in a much healthier state than it found it.
Milk Thistle and PainkillersOver the counter painkillers such as Tylenol and paracetamol are based upon a chemical known as acetominophen. Milk thistle can be used to reverse the damage that acetaminophen can cause to your liver if you catch it early enough. Here is how this form of painkiller can cause damage to your liver. Acetaminophen undergoes processes known as sulfation and glucuronidation prior to being excreted from the body. This process is not harmful to the liver, and is a normal biochemical means of removing excess acetominophen from your body after it has done its work. However, if you have taken excess acetaminophen (>4g/day or 8x 500mg tablets) there is too much for the above process to handle, and a secondary biochemical route (the cytochrome p-450 system) is taken that generates an intermediate product known as NAPQI. Normally, this NAPQI is safely metabolized by the antioxidant glutathione but if there is insufficient glutathione in your system then the NAPQI will destroy cells in your liver. That can occur if too much acetaminophen has been taken for the glutathione to handle, if alcohol is also involved or if the diet of the patient is nutritionally deficient. If left untreated this condition can be resolved only by a liver transplant, without which it is usually fatal. Milk thistle can help to repair this damage and survival is more likely with patients who take milk thistle than those that do not.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2213) Agave Nectar
Date:
April 08, 2010 04:31 PM
Reading through the attack articles and blogs that have surfaced recently one could think that using agave is bad for one's health. These claims are utterly false and misleading. They are extreme views drawn from extreme examples and applied way out of context. They are propagandizing and clearly designed to frighten, not educate. All of the fears and concerns associated with the overconsumption of sugars and calories in general have been unfairly cast on agave. What is a "healthy" sweetener? One that you use moderately and sensibly. Health concerns related to fructose and caloric sweeteners are all dependant on the overconsumption of them. All foods have calories and it is the overall consumption of calories that lead to obesity and related issues, not any one food source.
Agave's caloric value is comparable to the other sweeteners in the category. Due to its greater sweetness though, less agave is used compared to the others, so agave actually can reduce caloric consumption per serving. This is due to a higher fructose content. The higher content does not mean higher consumption though, due to the smaller portion used. But, it is not the single serving that matters, it is the number of servings which lead to the overconsumption issues which may result in health concerns. As a reference point, 9-10 teaspoon servings of agave would be the approximate caloric equivalent of one 16 oz soft drink. With this perspective, is agave really being overconsumed as a choice of sweetener for home use? Every single health issue which the attackers have tried to associate with agave is really the result of a caloric overconsumption issue. There are no documented issues with normal, moderate consumption of agave or sweeteners in general as part of our everyday diet. For reasons unknown, some have attempted to isolate agave from the real world and real world conditions with the goal of inhibiting agave's use. They play on people's fears, reference false information and fail to address health issues in any meaningful way. The purpose of this article is to debunk the controversial misinformation surrounding agave. All information debunking the myths and misinformation is based on current science and facts. It is our goal to provide you with useful information so that you can make your personal nutritional choices in a well-informed, science-based manner. The Agave Controversy: Exposing the fraudulent article by Rami Nagel By Dr. Susan Kleiner, PhD, RD, FACN, CNS, FISSN And Craig Gerbore, CEO Madhava
The controversy about agave syrup was manufactured by the publication of a single article on the internet, which has been reproduced and adapted for virtually every other article produced on the internet and other media venues. That article, written by Rami Nagel and published on Naturalnews.com, was highly biased and full of inaccuracies, half-truths and misinformation about agave. Since the Naturalnews.com article has been the sole source of nearly all other popular articles in public media, we want to set the record straight with science-based, reliable information to offer a more balanced resource to those interested in learning more about agave syrup. According to the description on the Naturalnews.com website, Rami Nagel is a "citizen journalist". This means that Mr. Nagel is self-employed, and not employed as an in-house journalist by the website. He wrote and published the article without any editorial or content oversight, and the editor of the website, Mike Adams, makes it clear that the article was not checked for incorrect or inaccurate information or facts. The introduction to the article, written by Mr. Adams, states that readers had written to comment that Mr. Nagel's resources were biased with conflicts of interest due to their financial interests in competing sweeteners, such as brown rice syrup. So even the website editor himself states that the article is not fact-checked, and it is biased and unbalanced. Who is Russ Bianchi? The sole resource interviewed for the article is Russ Bianchi, identified by the author as Managing Director and CEO of Adept Solutions, Inc. Mr. Bianchi has clear conflict of interest ties to the sweetener industry. We have documentation of the fact that Mr Bianchi had plans to market a product named Replace. It was to be touted as a low calorie alternative sweetener composed of natural and artificial ingredients! Mr Bianchi was prevented from marketing this sweetener as the result of a lawsuit against him by the owner of the formula. Mr Bianchi is quoted by Nagel extensively and exclusively. Many, if not all, of his statements are blatantly false or misrepresentations of fact. He is clearly propagandizing against agave nectar. Was anyone else interviewed for this article?
Yes. Craig Gerbore, president and owner of Madhava Agave Syrup, was extensively interviewed by the author but no parts of that interview were included in the article. It is important to note that neither Mr Nagel or Mr Bianchi have not made themselves available for questions on their statements since the articles appearance. They remain out of sight and have entirely avoided the controversy their statements created. What is agave nectar? The opening line of this paragraph in the article by Mr. Nagel states: "The principal constituent of the agave is starch, such as what is found in corn or rice." This is absolutely false. There is no starch in agave. The source of carbohydrate in agave syrup is inulin, a polysaccharide made up primarily of strings of fructose units. Starch is a polysaccharide made up of strings of glucose molecules. They are significantly different, and this difference is why agave syrup is naturally sweet. The very basis of the argument presented by Mr. Nagel is false. The Process The agave plant is a succulent, similar to a cactus. The agave sweetener comes from both the Salmiana agave plant and the agave Tequilana (Blue Agave) which are both organically farmed in Mexico and certified organic by USDA approved certifiers. As the salmiana plant grows it produces a stalk called the "quiote" and when this is removed, a natural liquid called "aquamiel". The liquid is collected from the plant, while Blue agave pinons are harvested and shredded to remove the similar juice. Either can be naturally processed thermally or by enzymes into agave nectar. The juice of the plant is not naturally sweet. The string of connected fructose units that makes up the major proportion of inulin does not have a sweet taste, but when the fructose units are separated (the process is called hydrolysis) by the addition of an enzyme, similar to digestion, or thermally for most blue agave, the syrup becomes quite sweet. That is the entire processing chain for agave nectar. There are no additives, other ingredients or chemicals in Madhava agave nectar. It is absolutely pure and organic and GMO free. ? Mr. Nagel claims that agave syrup is a "refined corn fructose" similar to high fructose corn syrup. This is absolutely false. There is no relationship between agave syrup and high fructose corn syrup in any way, including the source of the product, or the manufacturing process. ? Mr. Nagel refers to a "confidential FDA letter" from Mr. Martin Stutsman, claiming that agave is fraudulently labeled. We contacted Mr. Stutsman at the United States Food and Drug Administration, and his response made it clear that there was never a "confidential FDA letter". He did publish a public letter referenced in an FDA document as "FDA letter from Martin Stutsman to Dr. Eric Wilhelmsen (Wilhelmsen Consulting), May 8, 2000", regarding evaporated cane juice, a topic wholly unrelated to agave syrup. ? He continued in his response to us that the paragraph in Mr. Nagel's article inaccurately reflected the substance of his comments in the document. This link will take you to the original document in which the letter was referenced (reference #2): //www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/FoodLabelingNutrition/ucm181491.htm In fact, Mr. Nagel fabricated the entire story of the letter. Mr. Stutsman is a lawyer, not a doctor. The quotes were completely taken out of context from the document, and the quotes never referred to agave syrup at any time. Nagel goes on to further misrepresent Mr. Stutsman's intent in the published document by weaving in other inaccurate information that is thoroughly unrelated to the original document. Mr Bianchi's subsequent statements on labeling issues are false and without merit. Mr. Nagel is clearly caught red-handed. He has misrepresented the words of a government official, lied about the facts, and twisted the information to achieve his own agenda. This strategy is repeated throughout the article. ? Mr. Nagel continues his deceptive writing by referring to a quote by the late Dr. Varro Tyler in his book, The Honest Herbal. The first line of the paragraph is a direct quote from the book. Nothing else in that paragraph remotely resembles anything else found in Dr. Tyler's book. Mr. Nagel is trying to claim that agave syrup contains large quantities of saponins, and that they can be harmful to health. Here is the debunking of that paragraph: 1. Dr. Tyler does not include the variety of agave plant used for agave syrup. 2. The entire discussion is about the use of the sword-shaped leaves and the stem. Agave syrup is produced from the natural liquid in the plant. The saponins are isolated from the leaves of the plant. 3. There is no documented evidence to suggest agave syrup contains worrisome levels of saponins and the entire rest of the discussion about health dangers is fabricated and false. Sugars People are going to continue to consume sweet food and drink. There are only three categories of choice to sweeten food. Those are artificial sweeteners, stevia, or caloric sweeteners from natural sources, sugars. Most people will not choose artificial. Many will not choose stevia. That only leaves the category of sugars. In this group, agave is a good choice due to its organic quality, ease of use, neutral flavor, low glycemic index and the fact that less is used to equal the sweetness of the others in the category. The sweeteners in this category are composed of three primary sugars used to sweeten foods: glucose, fructose and sucrose. These sugars belong to a class of compounds known as carbohydrates. "Saccharide" is a term that denotes sugar, or substances derived from sugar. Monosaccharides are simple or single sugars; disaccharides are derived from two joined monosaccharides and when they are hydrolyzed, or separated, they yield two molecules of simple sugar. Strings of more than two sugar molecules are called polysaccharides. This category includes compounds such as starches, cellulose and inulin. Glucose and fructose are monosaccharides. Glucose and fructose are found abundantly in nature in fruits and plants. Sucrose is the disaccharide formed by the joining of glucose and fructose, also known as table sugar. When comparing their relative sweetness, glucose is the least sweet tasting, sucrose is next, and fructose is the sweetest of the three sugars, measured as 1.4 times sweeter than table sugar. Because it is so sweet, people typically use less fructose when sweetening foods compared to sucrose. ? In the article by Mr. Nagel he states , "fructose is not what is found in fruit. Commonly, fructose is compared with its opposite and truly naturally occurring sweetener, known as ‘levulose' (made by nature)..." Another fabrication. In fact, levulose is just another name for fructose. There are various nomenclatures used in the scientific naming of compounds. Fructose and levulose are exactly the same thing; the names are interchangeable. It is no different than if you called your father, "dad", and your sibling called your father, "father". He would still be the exact same person. Fructose and levulose are different names for the exact same thing: a sugar found in nature. Mr. Bianchi also is quoted to say that the body does not recognize the fructose in agave. This is another false piece of propaganda which demonstrates just how far he is reaching. If this were true, it would have no impact on us. He immediately contradicts himself with the claims of detrimental effects caused by the overconsumption of fructose. Using Sugars Sugars can be compared to each other in their ability to raise blood sugar levels by using the Glycemic Index. The scale is set from zero to 100, where low numbers do not have much impact on blood sugar levels, and high numbers raise blood sugar levels quickly. Fructose is very low on the scale. Because agave syrup is high in fructose, it has a rating of 32 or lower. Honey, which has a higher proportion of glucose to fructose, has a Glycemic Index of 58. Sucrose has a Glycemic Index of 68, and glucose, serving as the index standard, is 100. All sugars, whether fructose, glucose, sucrose or others, contribute 4 calories per gram to our total diet. 1 teaspoon of sugar = 4 grams = 16 calories In addition to calories, sugars sweeten our foods offering a desirable taste and adding enjoyment and pleasure to our dining. During cooking and baking, sugars allow for browning and the unique consistencies of syrups, candies, frostings and frozen desserts. The varieties of sugars, such as crystallized table sugar, brown sugar, raw sugar, molasses, honey and agave nectar, among others, contribute different properties and flavors to foods. When you add your own sugar to foods you are in control of how much sugar you use. Most people would never add as much sugar as do the food manufacturers. Moderate amounts of sugar can certainly be enjoyed as part of a healthy diet for an active individual. Natural sugars are easily metabolized and utilized by the body, offering a very efficient source of fuel for physical and mental activity. Of course, sugars should be used in moderation in the diet. This can control calories and help create a diet that is dense in nutrients. Impact of sugar on health and disease ? The remainder of Mr. Nagel's article works to link agave syrup with the increased incidence of obesity, diabetes, metabolic disease, and the general rise of morbidity and mortality in the population. This is an overconsumption issue involving far more than the occasional use of agave. Here are the facts: • Rats that are fed a high fructose diet become obese and will develop the chronic diseases associated with obesity: insulin resistance, diabetes and metabolic disease. • No one should eat a diet that reflects this type of experimental diet. • Too much sugar in the diet, whether from fructose, glucose or sucrose, can be unhealthy. Diets high in sugar promote tooth decay and periodontal disease; create an overabundance of calories and a deficit of nutrients. This scenario typically leads to weight gain and the development of chronic disease. • Active individuals can include a moderate amount of added sugar in their diet without negative health consequences. When calorie intake is balanced with physical activity, sugar serves as an efficient source of fuel for muscles, the brain and the central nervous system. • According to the World Health Organization (2003), individuals can healthfully include 10% of their daily calories from added sugars. This translates into 200 calories for a 2000 calorie diet, or 12½ teaspoons of added sugar daily. Clearly, one can safely add a couple of teaspoons of sweetener to a cup of tea or coffee, or have a little sweetened food without worrying about their risk of developing disease. • Agave syrup, which is sweeter than other sugars and low on the Glycemic Index scale, is a good choice to include as one of the added sugars in your diet because you will use less sugar (and therefore fewer calories) and minimally raise blood sugar levels. Just a teaspoon of agave: the healthy use of sweeteners in your diet We all want to live healthier and longer lives. Diet and nutrition plays a key role, impacting our health and our ability to perform physically and mentally now and into the future. Food offers us not only sustenance, but also pleasure and enjoyment. Food is present in so many parts of our lives: at celebrations, business events, family events, religious and spiritual occasions, sports outings, the focus of our family meals, intimate dinners, and sometimes just the excuse to socialize. Sweet foods make us feel good. Sugar allows for the elevation of serotonin in our brains, the "feel good" neurotransmitter that elevates mood, helps us focus, and in the evening, helps us relax and sleep. Sugar is a source of energy for our muscles, brain and central nervous system. Without sugar our bodies will not function at peak capacity. Too much sugar, however, is not good. In small amounts sugar energizes us, but in large doses, repeated throughout the day, day in and day out, sugar puts stress on the body. The extra calories can lead to weight gain and obesity, which in time can lead to chronic disease. In the short term, high sugar intakes can lead to a nutritionally deficient diet and a sense of being on an emotional roller coaster. So be selective about your use of sugars and use them in moderation in your diet. Just like all foods, a variety will enhance the nutritional content of your diet and the flavor and tastes that you can enjoy. Since sugars come in different forms and have different flavors, they can be used most effectively in specific foods and beverages. For instance, agave syrup is liquid and less viscous than honey, making it easy to mix into cold liquids like iced tea and coffee, and is great to add to cold unsweetened cereals for a little sweet taste. Agave's mild flavor allows chefs and bakers to sweeten foods lightly, without overpowering the taste of the dish. Pay attention to how much sugar is added to your diet every day. Read labels so that you know when sugar is added to manufactured foods. Keep the consumption of added sugars in your diet to no more than 10% of your total daily calorie intake so that you have plenty of room for nutrient dense foods like fruits, vegetables, grains, dairy, protein-rich foods, nuts, seeds and healthy oils. Remember that nutrition is a science based on facts. We are making great advances in our understanding of the science of foods and nutrition. Beware of people with hidden agendas using fear tactics to influence your choices. Don't take their opinion at face value. What are their credentials? What conflicts of interest do they have? If they do not disclose conflicts, then assume that they are manipulating the truth. Most of all enjoy food. Think about what you need to eat to promote whole health. Don't overindulge, but don't deprive yourself of the bounty of wonderful tastes, either. Use celebrations as occasions to enjoy your favorite foods and try new ones. A teaspoon or two of sugar easily fits into the diet of an active, healthy person. Agave syrup offers an organic low-glycemic choice for those looking for that option. Resources for this article: Charley H. Food Science, 2nd Edition. John Wiley & Sons, New York, NY, 1982. Figlewicz DP et al. Effect of moderate intake of sweeteners on metabolic health in the rat. Physiology and Behavior 98:618-624, 2009 Johnson RK et al. Dietary sugars intake and cardiovascular health: A scientific statement from the American Heart Association. Circulation: Journal of the American Heart Association, 2009 Tyler VE. The Honest Herbal, Third Edition. Pharmaceutical Products Press, New York, NY, 1993.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2152) DHEA and Your Health
Date:
March 16, 2010 12:27 PM
When DHEA levels are normal, it aids the immune system in maintaining balance and fighting diseases and infection. This, in turn, protects the body form a variety of serious problems that can occur, including cancer. Although the full extent of DHEA's benefits is not entirely known, there is a great deal of evidence that links low levels of DHEA to conditions such as cancer, Alzheimer's disease, arthritis, osteoporosis, chronic fatigue syndrome, diabetes, fertility problems, lupus, rheumatoid arthritis, multiple sclerosis, allergies, PMS, and even weight problems. Many people even believe that this hormone is the single most important factor in maintaining health.
Scientific studies have determined that individuals with cancer seem to have lower levels of DHEA than those individuals who are healthy. It has been found that DHEA has the ability to inhibit one of the most important enzymes that is responsible for the feeding of cancer cells. Research has also concluded that DHEA can help in a variety of types of cancer, including colon, lung, skin, breast, lymphatic, gastric, prostate, and ovarian. It is believed that DHEA aids in slowing the growth of cancer. This hormone also blocks some of the enzymes that are responsible for cancer proliferation, which helps to prevent the activity of cancer and stops damage from occurring. Alzheimer's condition is extremely frightening, as it deals with the loss of memory and senility. It has been found that levels of DHEA in Alzheimer's patients are forty-eight percent lower than the normal, healthy level established by the control group. DHEA is responsible for protecting the brain cells from damage and deterioration. Also, it is useful with other degenerative conditions that deal with senility. In healthy individuals, DHEA can be found abundantly in brain tissue, which protects against aging and damage. DHEA is a precursor for cortisol and adrenaline, both of which are stress hormones. DHEA can become depleted when the body is under stress due to the effect on the adrenal glands. Because of this, chronic stress can lead to lower levels of DHEA, which can be detrimental to one's health. It has been found the prolonged stress can lead to cases of depression, with depression being helped by the addition of DHEA. Individuals with depression have found favorable results when using DHEA. It has been shown that DHEA therapy is free of side effects when taken in proper amounts. Some problems that occur when excess amounts of DHEA are supplemented include acne, rapid heartbeat, irritability, and headaches. The majority of people solve these problems by lowering the amount they are taking. For more information on the many beneficial effects provided by DHEA, please feel free to contact a representative from your local or internet health food store. Dhea is a hormone naturally found in the body now available over the counter at your local health food store. ~video~
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2130) Fight Cold Sores And Build Collagen
Date:
April 29, 2009 10:18 AM
Lysine is an essential alpha-amino acid, in that it cannot be biosynthesized by the human body, and therefore must be taken in your diet or as a supplement. It is synthesized in plants from aspartic acid, and metabolized in the body to produce acetyl-Coenzyme A (acetyl-CoA). Before discussing its action on herpes, we shall first have look at how Lysine helps with the formation of collagen. Collagen is a protein that is produced in the body from lysine and proline, another amino acid. In fact the primary role of amino acids in your diet is as building blocks to form the much larger protein molecules. Collagen is fibrous, and forms the connective tissue such as cartilage, ligaments, tendons, blood vessels and skin. Even the external parts of the ears. It literally holds our skeletons together, and wraps the whole body up in skin, so if we had no collagen we would literally fall apart! Collagen is also used by body cells to form the matrix that the body cells use to attach to each other and is one of the most important types of tissue in your body. It is so ubiquitous that over 30% of the protein contained in your body is collagen, and it is designed for its structural strength as opposed to its ability to take part in chemical reactions as other proteins are. Lysine and Vitamin C are essential for the maintenance and formation of collagen. There is not a lot of lysine in collagen - only about 4%, but it is very active in the cross-linking that forms the fibrils of collagen. Fibrils are the hair-like structures formed in a triple helix arrangement by three protein chains twisting round one another. The fibrils are bundled together in a straight line that has amazing tensile strength. The tensile strength of collagen is, weight for weight, stronger than steel! In order for lysine to take part in this process effectively, some molecules have to be hydroxylated and others oxidized, forming aldehydes. Things can go wrong here, and deficiencies in the metabolic process can lead to some heritable conditions, or diseases of connective tissue. Among these are lathyrism, Cutis-Laxa and the Menkes kinky hair syndrome. However, lysine is a very versatile amino acid, and not only is it necessary for the biosynthesis of all proteins, but is also heavily involved in the production of enzymes, hormones and antibodies. It is an important component of the calcium absorption process, and also, as previously stated, can be used in the treatment of herpes simplex. This form of herpes is known commonly as 'cold sores', and is a result of the activity of the herpes virus. Viruses do not reproduce in order to ensure the 'continuation of the species', but replicate. In order to achieve this it requires the help of another amino acid, arginine. This is a common amino acid whose sources include grains, seeds, peanuts, raisins and chocolate. Lysine and arginine competes for the absorption and entry of tissue cells, and reduces the strength of arginine, so preventing the growth of herpes. For this reason a supplement of lysine can be used to reduce the effects of the herpes simplex virus, and lessen the symptoms of the cold sore. However, it is not only cold sores but other forms of herpes that lysine can help to relieve. Herpes zoster is a virus that causes shingles. This virus is generated by the reactivation of the dormant varicella-zoster virus left in the tissues after chickenpox. It is a recurrent condition, and lycine can help to reduce recurrences as well as its severity. Apart from being an effective defense against herpes, and forming collagen, the amino acid imparts several other benefits to the human body. Among these is osteoporosis. L-lysine is involved in calcium absorption in the intestine, and also helps to reduce the loss of calcium in the urine. In osteoporosis we have to try to make every calcium molecule ingested in the diet to be incorporated in the bone structure. L-arginine can work with lysine to enhance the activity of the body cells that produce bone. Canker sores are often mistaken for cold sores, but they are actually quite different. They are small sores inside the mouth, and appear in the form of very painful ulcers. The cause is unknown, but is believed to be a virus, and lysine appears to help the condition. Although there have been no proper clinical tests carried out on its use as a remedy for canker sores, lysine appears to help, and a supplement is recommended as a treatment by many doctors. It will do no harm, and anybody suffering from these tiny but painful sores will try anything. Although lysine deficiency is rare, it can occur, particularly amongst those observing a vegetarian macrobiotic diet, and also in athletes who frequently undertake vigorous exercise, especially with too little recovery time. The effects of a deficiency are fatigue, nausea, appetite loss, anemia, slow growth and kidney stones. The latter is likely due to a failure to absorb calcium, that L-lysine promotes, and the formation of calcium oxalate and other insoluble salts in the kidney. Dietary sources include beans and other legumes, and although it should be available in cereals, baked foods and doughnuts, for example, the carmelization of sugars binds the lysine to the sugar, and so reducing its bioavailability. However, you can also get it in cheese, eggs, tofu and red meats. If you are taking an arginine supplement, you should consult your physician prior to taking lysine. The reason for this is that lysine and arginine share biochemical pathways, and arginine can reduce the effective concentration of lysine. However, it has not been tested by the FDA, nor approved, and any use is at your own risk. This risk appears to be very small, although its manufacture is not regulated. However, do not let this bother you: the proof of the pudding is in the eating as they say. Many have found lysine to be effective with collagen or herpes problems, and a supplement of between 3,000 and 9,000 mg per day is recommended for those with herpes viral infections. It is not recommended for children under two years old. Lysine is available at your local or internet health food store at discount prices. Look for name brands to ensure purity and quality of the product you purchase. Another Great Cold Sore Remedy is Red Marine Algae!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1998) Glycine
Date:
October 11, 2008 10:26 AM
The non-essential amino acid glycine is needed to generate muscle tissue and also for the conversion of blood glucose into energy. It is referred to as being ‘non-essential’ because the body can manufacture its own glycine, and is therefore not an essential component of your diet. Other uses to which glycine is put by the body includes the maintenance of a healthy nervous system, and is necessary for the proper functioning of the digestive system. Amino acids play three essential roles in the human body: 1. They are the building blocks of proteins: proteins comprise about half of the dry weight of the majority of your body cells, and without them there would be no life. They are produced using monomers known as amino acids, and there are about 20 different amino acids used to make the vast variety of proteins that make up the human body. Proteins are needed to form enzymes, the catalysts that permit the majority of chemical reactions within our bodies, and also genes, the building blocks of DNA. 2. More relevant here, amino acids play an important role in the production of ATP (adenosine triphosphate) from ADP (adenosine diphosphate) by phosphorylation with creatine phosphate. The more creatine phosphate available, the more ATP can be produced. Since ATP is the molecule responsible for the generation of energy, then the more ATP available the more energy is generated. Although creatine is available from many food sources, it is destroyed by cooking, and over half of what you use is made from the three amino acids, glycine, arginine and methionine. The energy produced in this way is very short-lived, and last only a few seconds - more on that later. 3. Glycine is heavily involved in the production of collagen, which is the substance that maintains the flexibility of your skin and other connective tissues while still maintaining their strength and firmness. Without glycine your skin would become slack due to the degrading effect of sunlight, free radicals and oxidation. The non essential amino acid, glycine, is believed to offer other benefits to the human body, but it is the second of those above, the production of ATP, which interests us here. ATP is an extremely important nanomolecule, second in importance to the body only to DNA, and possibly also RNA since the two are linked. RNA makes copies of your DNA structure for use in cell division and growth. When a cell expends energy for whatever reason, such as when I am typing this, or when your heart beats, or even when your liver synthesizes a protein, one of the phosphate groups is removed from the adenosine triphosphate molecule, and converts it to adenosine diphosphate (ADP). The ATP is then said to be 'spent', just as your energy is spent when you are tired and can exercise no more. The ADP is then immediately reconverted to ATP in the mitochondria, a part of every cell in your body. A cell can contain hundreds, or even thousands, of mitochondria, the number depending upon that particular cell's need for energy. Hence, cells in your muscles, or in your liver where most of the body's chemistry takes place, contain thousands of mitochondria whereas those in your scalp contain a lot less. Once changed to ATP, a phosphate is again lost when energy is expended, and so the cycle continues. Glucose is needed allow the ADP to be converted to ATP, hence the need for sugars, or the carbohydrates from which they are manufactured in your body. Each cell can contain up to a billion molecules of ATP, although the couch potatoes among you probably have a lot less! Your store of ATP molecules last about 2 to 5 seconds before being changed to ADP although more rapidly for athletes that expend a lot of energy. Then the energy stored in the form of glycogen in the liver kicks in for another 4 - 6 seconds. Additionally, you cannot expend more energy that the (eventual) sugars that you take in your diet, which can be in the form of ordinary 'sugar' (sucrose), fruit (fructose), glucose, carbohydrates that are metabolized into sugars, or any other member of the sugar family (e.g. lactose, maltose, etc.). Glycine is one of what are called glucogenic amino acids, which refers to their ability to provide glucose to the blood. Because it helps to maintain proper blood glucose levels, it is often prescribed for conditions that are caused by low glucose levels, such as hypoglycemia that shows symptoms of fatigue and tiredness, and also anemia and what is known as CFS (chronic fatigue syndrome). The one activity of the human body, in fact that of any mammal, for which ATP is essential, is the heartbeat. Without that no mammal could survive, or any other creature that relies on a circulation system for life. The only reason you heart has to beat is to pump your blood around your body, and it is your blood that contains the oxygen and nutrients needed to sustain life. Your cardiovascular health relies on lots of ATP being available to power each and every heartbeat. Analysis of the heart during the final stages of heart failure has revealed that there is a general decrease in the myocardial arginine: glycine amidinotraferase (AGAT) gene expression, which is indicative of the necessity of this enzyme for proper heart function. The enzyme is responsible for the first stage in the biosynthesis of creatine from glycine. Creatine is well known to athletes, and while it is available naturally from some food sources, it can be destroyed during cooking, and at least 50% of the creatine needed by the body is produced in the liver, pancreas and kidneys. It is creatine phosphate that is broken down into creatine and phosphate, the latter of which is used by the mitochondria to regenerate ATP from ADP.
The study carried out on the reduced AGAT levels found in heart failure patients indicates the importance of glycine to heart health. Without a good supply of glycine, there will insufficient creatine produced biochemically to generate the phosphate needed to for the ATP to produce the energy required to keep the heart pumping with the required strength. The energy provided by the mitochondria is used locally by the cells in which it is produced, and within a few seconds of that production. As explained earlier, ATP stores are used up within 2 - 5 seconds, and glycogen stores within another 4 - 6 seconds. That is why sprinters cannot keep running at maximum speed for more than around 10 seconds or so, because the immediate availability of glycine, and hence creatine, are insufficient to last longer than that. That is one reason why they have to finish those 100 meters as fast as possible, because otherwise they would run out of energy. Other than trying to win, of course! However, when it comes to the heart, ATP stores are essential, and the cells in your heart require a constant supply of ATP from creatine, which itself depends upon your intake or biosynthesis of glycine. Since dietary sources are insufficient to meet all your needs, and destroyed by cooking, a glycine supplement is the only way to ensure a sufficient intake. You cannot undernourish your heart and remain healthy.
ATP biosynthesis is essential if that of glycine theoretically is not, but the fact that 50% of your glycine requirement has to be produced by your body and the other 50% is sensitive to heat during cooking, a supplement of glycine could be essential to many people.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1912) Chlorella
Date:
October 10, 2008 09:23 AM
Each food we eat has a different, specific effect on the body. Meat and fish are rich in protein and help to build the body’s muscle structure, while carbohydrate foods like bread, rice, potatoes, and pasta are rich in sugar and are instantly converted to energy and also stored for energy. Vegetables and fruits have an abundant amount of vitamins, minerals, dietary fiver, and antioxidants that help other foods to do their jobs. Because each food has its own role in the body, getting the correct amount of each food is vital. One doctor suggests that what and how much to eat should be determined by the number and shape of the teeth. Since humans have four canine teeth for chewing meats, eight incisor teeth for vegetables and fruits, and 20 molar and pre-molar teeth for grinding staple foods, the ration should be meat one, vegetables two, and staple foods five for a well balanced ratio of eating. However, today’s typical diet is far from being well-balanced. Vegetables are usually what lack most in diets, which regulate the body. Because of this, meat dishes and staple foods can’t do their jobs and instead, remain in the body as fat, making improperly metabolized food cause disease. This unbalanced diet means that food becomes body fat and increased body fat causes hyperlipema, which clogs the blood with fat, but also raises the risk of diabetes, hypertension, and arteriosclerosis. Chlorella can be used to effectively supply the body with nutrients that are identical to vegetables. With eating being one of life’s joys, it is only human instinct to want to eat a lot of delicious food. This desire often influences our lives. However, eating an unbalanced diet can increase excessive body fat, leading to a variety of diseases. Along with balancing the diet, chlorella is able to cleanse the blood by eliminating the excess fat and making blood vessels more flexible. This helps to lower cholesterol in the blood and liver. Chlorella also has the ability to improve hypertension, improve diabetes, protect against arteriosclerosis, prevent stomach ulcers, and prevent anemia. The human digestive system is responsible for taking in necessary nutrients for the maintenance of life. The intestines can be considered the entrance to the body, where nutrients from food are absorbed. However, intestines are also the entrance for toxins, which can lead to various diseases such as colon cancer, arteriosclerosis, high blood pressure, cystitis, poor skin, headaches, dizziness, stiff shoulders, stomachaches, insomnia, anorexia, hemorrhoids, allergies, and lowered immunity. Some common toxins include dioxins, heavy metals, residual agricultural chemicals, food additives, and prescription drugs. All of these materials are highly absorbable, highly residual in the body, and not easily detoxified by just the liver.
It’s necessary to improve liver metabolism to detoxify and regulate the environment inside the body. Chlorella is able to detoxify the body by boosting liver metabolism and detoxify the poisons that are highly residual and not able to be detoxified by the liver. As a detoxifier, chlorella is responsible for the detoxification of PCBs, excretion of dioxin, detoxification of heavy metals, and improvement of constipation. Have you had your chlorella today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1911) EFA's - Essential Fatty Acids
Date:
September 15, 2008 09:42 AM
Many recent studies have found that EFAs may be extremely helpful for many chronic, stubborn conditions. Their continuously growing range of applications includes overcoming diseases such as alcoholism, breast cancer, and cardiovascular disease; strengthening the immune system; helping eliminate yeast infection; reducing symptoms of premenstrual syndrome; minimizing inflammation of rheumatoid arthritis; and assisting in the proper management of weight. Alcohol dependence is an extremely serious condition that often results in decreased life expectancy, suicide, degeneration of the brain and liver, osteoporosis, and many other conditions. For each person, the rate at which alcohol is metabolized in the body is different, as a lot of it has to do with the person's nutritional status, the concentration and activity of liver enzymes, and the rate at which alcohol is consumed. Alcoholics tend not to eat because the calories from alcohol, although nutrient-poor, diminish the appetite, causing many alcoholics to become extremely malnourished. An overall nutritional program should be employed to those people who are dependant on alcohol, which should include vitamins A, C, and B, complex, along with zinc, magnesium, selenium, amino acids, milk thistle, acidophilus, antioxidants, L-carnitine, and essential fatty acids. EFAs, especially those that are high in GLA, keep blood lipid levels from going out of control. The body's immune system has a vital role in protecting us against cancer, as it recognizes and annihilates any abnormal cells before they have the chance to multiply and do damage. When the immune system is overwhelmed or not functioning properly, abnormal cells will reproduce without having anything to stop them. Because of the rapidly growing tumors which have a huge appetite for nutrition to keep them going, cancer patients often become malnourished and lose weight. A diet that is rich in cruciferous vegetables, fiber, antioxidants, vitamins A, C, and E, minerals, and essential fatty acids can help prevent breast cancer. Research shows that EFAs, especially GLA, have anti-tumor properties. All of the cells in the body have a dependence on nutrients that are transported through the circulatory network. When blood vessels become clogged with fats and cholesterol, nutrition distribution is hindered and blood flow can be stopped in some areas, causing the heart to die. Exercise is a good for increasing circulation and keeping the blood from getting stuck. A diet that is high fruits, vegetables, natural fiber, and low in saturated fats, meats, and homogenized dairy products is also a good idea. Additionally, antioxidants, hawthorn berry, ginkgo biloba, vitamin E, Co Q-10, L-carnitine, calcium, magnesium, potassium, and EFAs will also be of benefit to the cardiovascular system. Essential fatty acids have been shown to stop the growth of yeast organisms in the body. They do so by helping the oxygen to flow to cells. Since yeast is anaerobic, it cannot thrive in the presence of oxygen. Yeast overgrowth can cause a variety of symptoms that are often diagnosed as another condition, ranging from joint swelling to memory loss. PMS is a collection of symptoms that occurs one to two weeks before menstruation, affects about one-third of women who are younger than forty. It is caused by hormone imbalances, which result in anxiety, irritability, and mental sluggishness. Research has found that women with PMS usually eat more refined carbohydrates, dairy products, and sodium, and less iron and other minerals than those women who do not experience this condition. Vitamin B complex, beta carotene, vitamin E, magnesium, milk thistle, acidophilus, and essential fatty acids are very helpful for PMS. Essential fatty acids, especially GLA, are helpful in balancing the body's hormone levels. Reducing symptoms of disease like arthritis or PMS is important to all those who suffer from them. EFA's can help reduce the symptoms of these diseases. American diets are low in EFA's and one should consume them either in the foods they eat or supplement form to help the body strengthen its self and fight off disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1890) Isoflavones
Date:
September 02, 2008 10:10 AM
An isoflavone from soy has been evaluated for its effect on various female functions such as the menopause and some effects on estrogens. Soy products have been part of the diet in the Far East for thousands of years, and it is a known fact that these people suffer fewer incidences of conditions such as breast cancer, menopausal problems, rectal cancer and diseases of the heart and joints. The benefits that such a diet appeared to confer on those taking it initiated many studies into the active constituents of soy, and how the biochemistry involved imparted these benefits. A result of this was an intensification of investigations into many so-called -women's functions' or 'women's problems' that hitherto had been accepted as a part of life. Now, however, they are better understood, just as many other components of the Oriental diet are being found to have wider implications in terms of disease prevention and increasing life expectancy. So back to soy and its isoflavone content. Soy contains a number of isoflavones, commonly known as phyto-estrogens - plant estrogens - because their chemical formula is similar to that of estrogen, a female hormone. Isoflavones possess some properties that support the beneficial properties of estrogens, and others that suppress some of the risk factors possessed by estrogen. We shall discuss here how these isoflavones are related chemically to estrogens, and how they can be used to support some specific female functions. In order to understand how isoflavones work we go back to the 1980s, when alpha and beta estrogen receptors were discovered. Until then, the biochemistry of estrogen was not fully understood, and problems connected with estrogen had not been fully investigated. Like all hormones, estrogen works by finding receptors that are located on cells. With regard to estrogen there are two types of receptor. The beta receptors are connected with the beneficial properties of estrogen, while the alpha receptors tend to lead to the unfavorable effects such as cancers related to estrogen. Each of your different tissue types possesses different ratios of these two receptor types. The unfavorable alpha receptors predominate in tissues such as the breast, ovaries and uterus. The favorable beta receptors predominate in the blood cells, bladder, prostate gland, thymus and bones. Studies have indicated that isoflavones appear to attack to the beta receptors and simulate the beneficial effect of estrogen when the levels of estrogen in the body are low, and allow the proper functioning of these cells in the body. The alpha cells are also populated by isoflavones, which then protect these areas of your body against cancers that can be stimulated by estrogen, such as cancers of the breast, ovaries and uterus. It appears that cancers that can develop when the alpha receptors are populated by estrogen do not occur when isoflavones have captured them Isoflavones are present in the form of glucosides. These are composed of sugar and non-sugar components, the latter known as aglycones, and the main isoflavones in soybean are based on the three aglycones genistein, daizein and glycetein. The glucosides are water soluble and are broken down into enzymes known as B-glucosidases in the intestine. This releases the aglycones that can be further metabolized into other substances. Current studies are examining the possibility that a diet rich in isoflavones taken early in life up to teenage years can reduce the incidence of breast cancer in later years. Isoflavones have been used in the laboratory to reduce the growth of prostate cancer cells, and animal studies have reinforced this finding. The fact that Japanese men suffer less from prostate cancer than those eating diets low in isoflavones also tend to reinforce this connection. The same mechanism can be used to in prostate cancer by binding to testosterone receptors. Genistein, in particular, can help treat certain types of cancer by inhibiting enzymes such as tyrosine kinase that can become hyperactive and overstimulate the growth of potentially cancerous cells. It is probable that the estrogen binding facility of isoflavones complements the activity of estrogen in women with low levels of hormone. When the female estrogen level is low, isoflavones can reduce the effects of the menopause and symptoms such as hot flushes and night sweats become less severe. While not all women benefit, it has been found that women with these symptoms tend to suffer less when taking a diet rich in soy foods containing isoflavones. In addition to its moderating effect on these cancers, and its effect on the menopausal symptoms on many women, soy isoflavones possess a few other beneficial health properties. They are strong antioxidants, and help to support the immune system by mopping up free radicals. They also help to protect from atherosclerosis by preventing the oxidation of LDL cholesterol and depositing it as plaque in the arteries. There is evidence that isoflavones in the diet can help to maintain strong healthy bones. This is largely through the fact that Chinese women taking a diet rich in soya suffer fewer fractures than those on a low soy diet, but studies are continuing into potential reasons for this. Estrogen receptors in bones regulate bone growth and density. Isoflavones can modulate these receptors and promote greater bone density just like estrogen hormones with out estrogen side effects. Isoflavones have few dietary sources, the richest being soybeans and other soy products. These are very low in the non-Asian diet, so few people, other than Asians, receive the benefit of these phytochemicals. This is believed to be the major reason for Asians suffering significantly lower rates of certain cancers than non-Asians. Soy milk and tofu are the richest sources, although there is no standardization of isoflavones in soy-based foodstuffs. This is because the isoflavone content varies according to growing conditions, although a diet containing the recommended quantities of soy foods, such as soy milk or soy beans, together with a low cholesterol diet, should help women to overcome many of the problems associated with excess estrogen, or a lack of it especially when taking in conjunction with essential fatty acids. Any supplement containing soy will be beneficial to most women, particularly during the menopausal stages, although the effect of isoflavones on certain cancers to which women are susceptible cannot be ignored. Such supplements should therefore be used by all women from at the teens onwards, studies having indicating that an isoflavone-rich diet should be beneficial over the longer term.
Isoflavones from soy is effective in helping to support female functions, although the normal Western diet is traditionally very short in these forms of phytoestrogen. Isoflavones can modulate estrogen receptor sites through out the body helping the body regulate its functions and easy the symptoms related to a estrogen deficient body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1880) Coconut Oil
Date:
August 18, 2008 12:01 PM
Whether coconut oil is good for weight loss or not, it is becoming an increasingly popular component of a weight loss diet. So how justified is this in view the fact that fats and oils are not normally regarded as being the best form of food to take if you want to lose weight? Apart from any other considerations, fats are actually very important components of any diet. Consider, for example, how many vitamins are fat soluble: vitamins A, D, E and K are all fat soluble, and without fats in your diet vitamins would not be able to circulate and be taken to where they do most good. Fats are also essential building blocks for hormones and cell membranes. In short, you cannot survive without fats. Coconut oil is a fat. In referring to coconut oil here, we are discussing virgin oil, not the refined form that is high in cholesterol. Refined, or processed coconut oils, is hydrogenated, which renders it more in nature to the longer chain fatty acids. Virgin coconut oil contains what are known as medium chain fatty acids (MCFA), which are easily metabolized by your liver into energy. The longer chain fatty acids, also called triglycerides, are not easily broken down into smaller components, and tend to be stored in the body as fat. This fat can be particularly dangerous if stored round the midriff, and so long chain fatty acids are dangerous to your health. This does not apply to MCFAs, and a possible mechanism for this is discussed later. An inability to distinguish between the different types of fats and oils in your diet is largely due to a lack of education in the chemistry of fats, and the lumping together of all fats and oils under the 'fatty' flag. Perhaps it is the use of the word 'fat' for the overweight condition and the fact that the triglycerides and other chemicals are known generically as 'fats' that triggers a connection between the two, but although this is logical, and in some cases justified, it is not always the case. There are fats and fats, just as there are lubricating oils and greases, and edible cooking oils and greases. The fatty acids in coconut oil are composed of relative small carbon chain lengths. Caprylic acid and capric acid contain 8 and 10 carbon atoms in the backbone compared to the 18 of the stearic acid that is commonly contained in animal fats. The longer the carbon chain in the molecule, the more difficult it is to break down, and the more likely it is to be stored in the body as a dense fatty deposit that places a strain on the heart. Due to the shorter chain length the medium chain fatty acids hold less energy per unit weight. Apart from any other reasons then, coconut oil contains fewer calories than other fats and so if used as the bulk of your fat requirement, will be less liable to generate body fat. Not only that, but as inferred earlier, due to the smaller molecule these calories are more readily released as energy for use by your body rather than stored unused. However, that is not the whole story on either count: coconut contains saturated fats, and also monounsaturated and polyunsaturated fats, although in small quantities. These, however, are present in only small amounts, although would still be expected to undergo oxidation and produce the rancid taste commonly found in aged unsaturated oils and fats. However, even after a year this does not happen, which indicates that coconut oil possesses some form of antioxidant properties. This is confirmed by the fact that people eating a diet rich in coconut oil has less of a need for the strong oil-soluble antioxidant vitamin E. In fact, the metabolism of fats is usually connected with the carnitine transport system in the mitochondria, although the shorter chain fatty acids do not need carnitine for their metabolism. What happens then is that because carnitine promotes oxidation during stress, and causes oxidative damage to body cells, its absence in metabolism of coconut oil fatty acids results in a reduction in the oxidation that degrades unsaturated fats. Hence the lack of rancidity. Taking this further, then, this lack of oxidation infers that those that take a diet rich in coconut oil (for example using it for cooking rather than animal and vegetable oils containing longer chain fatty acids) should be partially protected against cell oxidation in general. Oxidative effects such as aging, cardiovascular diseases and some cancers should be reduced, and studies have shown this to be the case. Those consuming coconut oil rather than other oils tend to age more slowly, suffer less from heart disease and tend to experience fewer incidences of cancer. With regard specifically to weight loss, it is believed that consumption of medium chain triglycerides, as opposed to longer chain triglycerides, results in a higher rate of thermogenesis, or the conversion of carbohydrates to energy (fats are also carbohydrates). The first step in this process requires the presence of Coenzyme A in the form of the enzyme acyl-CoA-dehydrogenase, and measurement of the activity of this enzyme has indicated that medium chain triglycerides exhibit much higher expenditure of energy than the metabolism of long chain triglycerides when being converted to fatty tissue. However, though the energy used up in this reaction, known as lipogenesis, was higher, the formation of fatty tissue was the same. Hence, MCA uses more energy to produce the same amount of fat as LCA, and therefore, although more energy is used up, no new fat is generated by the liver. Since your dietary fat intake can ultimately have only three fates: burned as energy, stored as the emergency energy source glycogen, or deposited as fat, then it is logical that the more energy generated then the less fat will be stored. In this way, coconut oil, with a high content of medium chain fatty acids, has a scientific explanation for causing weight reduction when used as a source of fat in the diet rather than animal or other vegetable fats or oils. It is converted to energy rather than fatty tissue, and if you exercise to use up that energy then your weight loss can be significant.
What this theory also states, however, is that coconut oil should be used as a replacement for other fats, and not in addition to it. If you take coconut oil in addition to your normal diet, do not expect to see results.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1870) Calcium D Glucarate
Date:
July 25, 2008 10:57 AM
Studies have found that D-glucarate has therapeutic actions; among these are cancer prevention and serum cholesterol reduction. However, its most impressive property could be its ability to quickly detoxify the body of both artificial and natural toxins which can be potentially harmful. These toxins can be neutralized in many ways, with glucuronidation being one those ways. The process of glucuronidation involves using the liver to neutralize chemical carcinogens and steroidal hormones including estrogen. Once a toxin has been glucuronidated in the liver, it goes to the bile and is eventually eliminated from the body in the stool. Beta-glucuronidase is an enzyme that is produced in the gut by unfriendly bacteria which can actually inhibit this process by chemically splitting a glucuronidated toxin before it is able to be eliminated in the stool. This unbound toxin can come into contact with the bowel lining where it can be reabsorbed and the whole process will be repeated. When a situation like this happens, cells are exposed, once again, to the chemical and the liver can become overworked. Thankfully, if D-glucarate is present, beta-glucuronidase is inhibited, resulting in a flawless glucuronidation in the body. These findings suggest that taking D-glucarate orally as a supplement can provide us with the increased ability to efficiently and rapidly rid our bodies of toxins through problem-free glucuronidation. Additionally, D-glucarate does not work like an antioxidant, which neutralizes free radicals, but instead actually forms a type of bond with harmful compounds to enhance their rapid removal from the body. Some of the organs that can be especially toxin-sensitive are the breast, prostate, liver, lung, and kidney, therefore, they can greatly benefit from this process. These organs can be most damaged by the continued exposure to poisons and carcinogens. Because our generation, more than that of any other, is exposure to a great number of potentially harmful environmental pollutants, our contact with carcinogens increased exponentially. Just some of the cancer-causing agents include cigarette smoke, pesticides, radon, hormonally-fattened meats, diagnostic and therapeutic x-rays, gamma radiation, trans-fatty acids, alcohol, poor diets, xeno-estrogen, herbicides, smog, car exhaust, certain prescription drugs, ultra-violet light, rancid foods, saturated / hydrogenated fats, some food/water supplies, and food preservatives. Although a lot of us have taken necessary measures to protect ourselves from exposure to the substances listed, it is inevitable that we will consistently take chemicals that can prompt the growth of cancer into our bodies. Additionally, our own hormones can be a threat if they are not efficiently metabolized and excreted from our body. One study found that Glucarate supplementation amplifies the process by which carcinogens and hormones are removed from the body, while D-glucarate can exert a positive effect on different stages of the carcinogenic process. It has been found that lower cancer rates in some populations could be attributed to their consumptions of foods that are rich in D-glucaric acid, self-medicated with D-glucarate, or combine D-glucarate supplementation with other chemopreventive agents.
Either way, the protective function of glucarate in the body’s natural cancer prevention mechanisms has been established for long periods of time, while other recent studies have indicated that the use of glucarate could potentially present a fifty percent decrease in tumor incidence.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1843) DIM For Estrogen Balance
Date:
July 10, 2008 03:26 PM
Diindolylmethane from broccoli can help with estrogen balance: There is plenty of evidence to suggest that, but before discussing the whys and wherefores, let's first have a look at the substance, where it comes from and why it should have any effect on estrogen or its balance. Diindolylmethane is an indole contained in brassicas such as broccoli, cabbage, kale, brussel sprouts and cauliflower. It is a dimer of indole-3-carbinol, which is itself formed by the autolytic degradation of glucosinolate glucobrassicin which is found in brassicas. Both this and the dimeric diindolylmethane are currently being tested for their antioxidant, anticancer and antiatherogenic properties, although this type of research has been mainly made on animals. When the cell walls of brassicas are ruptured, the enzyme myrosinase is released, that breaks down the glucobrassicin. Because diindolylmethane is oil soluble it is more bioavailable to the body in the presence of vitamin E and other lipophilic substances, and these are normally included in oral supplements. However, back to estrogen and its effects upon human estrogen balance. Estrogen is the name for a group of steroids that function substantially as the female sex hormone. They have many effects on the body, including regulation of the menstrual cycle, breast development and promote the formation of secondary female characteristics such as reduced height and muscle mass. Estrogen is also present in the male, where it regulates several factors pertaining to the reproductive system. It does not, however, take part in the process that determines sexual desire. If all of these properties are considered it would seem logical to believe that estrogen levels could be used to control weight increase, although claims that it can be use to enhance sexual performance seem ill founded: based more on hope than on science! What science appears to have found, however, is that estrogen dominance, due to an imbalance between estrogen and progesterone levels in the body, can give rise to increased weight, and even obesity, in women. It can also lead to uterine, ovarian and breast cancers, and cervical dysplasia which, while not cancer, can give rise to cervical cancer if not treated. Estrogen imbalance, therefore, is not good news and something to be avoided if it possibly can. So what can be done to avoid it? The answer is to find a hormonal balance, and this is where diindolylmethane (DIM) comes in. The substance has been found to have a positive effect on the balance between estrogen and progesterone, although eating broccoli will not be sufficient to do the job properly. Insufficient DIM is released by breaking the cell walls of broccoli through chewing to have much effect on the balance, about a kilo of broccoli a day being needed to have any noticeable effect. It is the diindolylmethane supplements that are able to have the desired effect in restoring the hormone balance and eliminating the undesirable effects of estrogen imbalance. But why should estrogen imbalance occur? What are the factors that cause this dangerous condition, and if it is so common how did our ancestors manage without today's science? The answer to the second question lies in that to the first, but before we discuss that don't go thinking that your ancestors managed through thick and thin. Perhaps yours did, but your life expectancy is significantly greater than that of your parents when they were born. In fact, you don't have to go too far up your family tree to when you would be doing well if you hit forty! So the argument about your ancestors doesn't wash. In fact, an estrogen imbalance can be caused by several factors: a slow estrogen metabolism that leads to an excess of estrogen because it is not broken down quickly enough is common, but far more common is the effect of pollutants such as pesticides, car exhaust fumes, emulsifiers, household cleaners and even some soaps. They contain chemicals known as xenoestrogens that our body believes to be real estrogens. They can stick to estrogen receptors on healthy cells, and can also prevent true estrogen from binding to the cell it should bind to. This results in an increase in free estrogen that cannot bind to the estrogen receptors that it should. Your ancestors did not have these problems with such 'estrogen mimics' and so managed just fine. There is also the fact that estrogen can be broken down in the liver by means of two different routes: one leads to a form of estrogen that metabolizes to provide many benefits, such as strong bones and a reduction in heart disease, while the other has the opposite effect of causing cancers, depression, osteoporosis and problems with your immune system. That is by no means the full list: you don't want to see that, believe me! You might think that if estrogen is dominant over progesterone, then taking progesterone would resolve the problem. It would seem to be a good cure. In fact, it is not a good idea since progesterone can be metabolized into yet more estrogen, making the problem even worse. The real answer is to take a supplement containing the substance that solves the problem by changing the estrogen metabolism pathways in the liver: diindolylmethane. More of the so-called "good" estrogen metabolites are formed, and less of the bad. The actual estrogen levels are not changed, but the way in which the excess estrogen causes harm is changed. That way, it doesn't matter what the imbalance is, the estrogen cannot do ham to your body. DIM possesses many potential positive benefits when used as a supplement. It can reduce your chances of getting breast, cervical and ovarian cancers, and also acts as a strong antioxidant, and helps to strengthen your immune system. It might help you to lose weight, but more studies are needed before this can be claimed conclusively. However, there is evidence at the moment that it has a weight reducing effect.
Its effect on sexual health is largely unfounded, but the effect of a placebo in this area can be astounding: that indicates how much psychology has to do with sexual performance. Nevertheless, the known and projected benefits of diindolylmethane are so significant that taking a supplement would seem a reasonable thing to do, and although your mom was right about you eating your broccoli, brassicas alone are not a rich enough source for a significant effect.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1835) Trace Minerals
Date:
May 09, 2008 11:09 AM
Colloidal trace minerals are just as important to our health and well being as vitamins. Practically since birth we have had it pounded into us that we must eat our vitamins if we are to be healthy. The fact is that vitamins are of little use to you without minerals which are as essential for your metabolism as any vitamin is. The essential minerals are the inorganic equivalents of the essential organic vitamins. They work together to maintain the biochemistry that keeps you alive. Take calcium, for example. That is a mineral needed for healthy teeth and bones, among many other things, but it is no good without vitamin D. Magnesium and potassium are also needed for healthy bones. Take blood clotting: vitamin K is the blood clotting vitamin, but blood will not clot without calcium. How is energy generated in your body from the carbohydrates and sugars that you eat? They are converted to glucose that is converted to energy in every cell in your body and used in-situ. Your heart gets the energy to beat from cells in the heart – energy does not float around the blood waiting to be used. It is generated by means of the production of a substance known as ATP – adenosine triphosphate of which phosphorus is an essential component. Without the mineral phosphate none of us would be alive – nor would any form of life for that matter. ATP is the universal molecule of life. So far we have discussed some of the seven major minerals: calcium, magnesium, potassium, phosphorus, sulfur, sodium and chlorine. There are many more that your body needs, and estimates vary from 45 to 70 trace minerals, without which you would find it difficult to function properly. Although your body can make many of the organic substances needed for life from vitamins, amino acids, fatty acids and proteins, it cannot make minerals which have to be taken in as part of your diet. They must be taken in your regular diet or as a supplement. In the USA a major mineral is one that is needed in amounts greater than 100 mg (0.1g) a day, and trace minerals are required at less than 100 mg a day. So one that is needed at 100.1 is major, and one at 99.9 mg is trace. Is there a difference in the source of trace minerals, or would any source be good enough? The answer lies in the construction of the human body, and the way in which it absorbs minerals. Your body is not designed to absorb metallic minerals. The way that such minerals are available in your diet is as part of larger organic molecules, and this is the way they must be taken as a supplement. Thus, you can’t just drink a soluble metal salt because it will pass straight through you with only around 5% absorption, if it doesn’t poison you first. For supplement purpose, metallic minerals are chelated, or combined with larger organic molecules such as proteins and amino acids, and this increases absorption to as high as 50%. The necessity of trace minerals in the human diet was not discovered, as much as the result of a number of studies on various societies and remedies that appeared to have no basis for their effects. The Hunzas and Azerbaijanis, for example, are known to live very long lives, and investigations into this showed their diet was very rich in colloidal trace minerals from glacial water and food grown in soil enriched by that water. It was through studies such as this and also investigation into the metabolites obtained from liver extracts that indicated the importance of many trace minerals. Take arsenic, for example. A known poison in larger quantities, trace quantities have been found to be metabolized by the liver, and while no studies have been carried out on the use of arsenic as a trace element in human biochemistry, studies on rats and human liver extracts have indicated that it could have a part to play in normal growth and reproduction. Trace minerals take part in many enzyme reactions, and physicians now agree that many health conditions could be enzymic in origin. It follows, then, that trace elements are important in maintaining good health. It is certainly true that we cannot live without any of the seven major minerals. And it is just as certain that many of the trace minerals are just as import to human biochemistry as the major ones. It is certainly true of vegetables, which are less complex biological entities than humans, and if tomatoes need at least eight known minerals for good growth then it is certain that we will need a lot more. No studies are needed to convince us of that. Take zinc, for example. Zinc is essential for proper liver function, wound healing and reproduction: spermatogenesis, the proper development of the primary and secondary male sex organs, and all area of the female reproduction process. Zinc is classed as a trace element, as is selenium, a deficiency of which can lead to heart disease, mental retardation and impaired function of the thyroid. Selenium deficiency is not common in the West but is in China where many areas are depleted of selenium. However, if zinc and selenium are known to be essential, how many of the other seventy or so trace minerals are also essential to human health? The trace minerals in general are believed to protect us from some degenerative conditions, the effects of environmental pollution and help to protect us from the effects of an excessive intake of toxic minerals. Although there have been insufficient studies carried out on most trace minerals, it is known that they should be taken in chelated form, metallic in nature or not. It is also known that such minerals should be taken as a balanced mixture as found in nature. A bullet approach, using an individual mineral to treat a certain condition, could lead to an imbalance in the body, and severe side effects, some of which might not yet be known. What is known is that certain minerals are tolerated by each other in specific relative concentrations, but if this balance is upset then they can inter-react and produce unpleasant side effects on, for example, the delicate balance of minerals in the blood. It is becoming increasingly clear that modern farming methods have resulted in mineral depletion of the soil, and that our normal diet now only contains a small number of the minerals that our forefathers were taking. Plants draw up minerals from the soil when they grow, and we take in these when we consume them or the animals that live on them. Saturation of the soil year in year out by chemical fertilizers low in or devoid of trace minerals has resulted in a sterile environment for our feedstock, and has made colloidal trace mineral supplements almost mandatory for good health. Today’s plants can contain fewer than 20 minerals, compared to the 70 plus of our ancestors. Life expectancy is increasing in spite of our increasingly poor diet rather than because of it, and is due more to medical advances than to advances in agriculture. A mineral supplement does seem necessary, but when you take one it should be balanced so that no one mineral is in excess at the expense of another. This helps to reduce the possibility of overdosing on an individual substance while maintaining a natural balance of minerals in your body to make sure that your normal biochemistry is not interrupted by some deficiency or excess that has yet to be discovered. While this might seem a spurious argument, you can be certain that those in the past that used cadmium and lead as cosmetics would rather have known the effects of these toxic substances that eventually killed them.
So use chelated trace mineral by all means, but make sure that they are balanced and tested so that nothing is present that can upset the normal balance of minerals in your body. If they work for tomatoes they should work for you!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1786) B Vitamin Supplements
Date:
May 07, 2008 03:18 PM
The fact that B vitamins have had to be coenzymated before they can be used by your body has been known for some time, but it is only over the past few years that they have been made commercially available in that form. Before we discuss the B vitamins in their coenzyme form it might be appropriate to discuss what coenzymes are and how they differ from ordinary enzymes. An enzyme is like an organic catalyst: it takes part in biochemical reactions by allowing such reactions to take place, but itself remaining unchanged. All enzymes are proteins formed in your body from amino acids and other protein material. A coenzyme, on the other hand, is somewhat like an enzyme for the enzymes, in that it is needed for the enzyme to do its job. Without a coenzyme, many enzymes could not promote the biochemical reaction it is responsible for. The B vitamins are all water soluble, which means that they are readily excreted and it is not impossible that if you take a B vitamin supplement, the whole lot will be immediately excreted in your urine if not used by your body. Whether they are or not it is a fact that your body can quickly become depleted of the B vitamin group, especially if you drink a lot. Alcoholics in particular are frequently vitamin B deficient. Although the liver can store unused vitamin B, they are only very small quantities and insufficient to prevent a deficiency. A deficiency in the B vitamins can cause a wide range of unpleasant conditions that are rapidly remedied with supplements. Pellagra is due largely to a deficiency in Vitamin B3, and causes hair loss, horrible skin lesions and many other side effects that you don’t want to know about. Vitamin B12 deficiency can cause loss of memory, and is common in alcoholics and some vegetarians (vitamin B12 is animal derived). Other symptoms of a general B vitamin deficiency include exhaustion, heart palpitations, fibrillation, anxiety, restlessness, attention deficit disorder and many, many more. It is not pleasant so you make sure that take enough vitamin B in your diet: dietary sources are far superior to pills although supplements will help you get over the symptoms of the deficiency until your diet takes over. Supplementation is also a good way to maintain a regular supply of vitamin B complex irrespective of your diet. The effects of a deficiency are so bad that a regular supplement is well worth taking. However, back to coenzymes and why they are needed for the metabolism of B vitamins in your body. Most B vitamins are, in fact, coenzymes themselves. Keep in mind that the definition of a vitamin is an organic substance that is essential for the normal health of your body. If you lack even one vitamin, your health with suffer and eventually you will be likely to die. That describes all of the B vitamins perfectly, and they also just happen to be coenzymes. This is not coincidence, of course, and their biochemistry must have been recognized before the concept of coenzymes was formulated. The B vitamins proper consist of eight distinct proteins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), B9 (folic acid), B12 (cyanocobalamin), and biotin and pantothenic acid. They are all essential components in human and animal metabolism, and most are also coenzymes. Every cell in your body depends on B vitamins for its existence, which is why pregnant women should include a good supply of them in their diet, especially folic acid (B9). They are essential for the cellular development of the fetus. Folic acid is necessary for the synthesis of nucleic acids that allow cell growth and the production of red blood cells. However, not one can be placed in importance above any other since they are all essential. With respect to the coenzyme factor, the vitamin B coenzymes are responsible for many of the biochemical reactions upon which life depends. Coenzyme B-12 for example is essential for two types of reaction that it catalyzes, one being a hydrogen atom exchange with alcohol and amine functional groups, the other being connected with methyl group transfer between molecules. In humans, the first of these is responsible for an essential step that results in energy being metabolized from fats and proteins in the mitochondria and the second for DNA production in cells that is indirectly responsible for growth. Each of these is why a vitamin B-12 deficiency leads to excessive fatigue and also a lack of fetal growth (although folic acid can make up for the latter deficiency). Thiamine (Vitamin B1) is a coenzyme for the metabolism of carbohydrates to energy. In the body it is present in the form of thiamine diphosphate, a coenzyme that assists in the decarboxylation of pyruvate as part of the citric acid cycle, otherwise known as the Krebs Cycle, that takes place in the mitochondria and is responsible for the generation of energy through aerobic respiration. Another coenzyme that is involved in the Krebs Cycle is formed in the body from Vitamin B3, or niacin. This coenzyme, nicotinamine adenine dinucleotide, has a redox potential and can store energy for use later on. Vitamin B5 can be converted in the body to Coenzyme A that not only breaks proteins down into individual amino acids, but also takes part in the first part of the Krebs Cycle. There is a common pattern emerging here where the B vitamins have an important part to play in the generation of energy from fats and carbohydrates. Similarly, Vitamin B6 is present in the body as the coenzyme Pyridoxal 5'-phosphate that helps to break down the body’s emergency energy store, glycogen, into energy when needed. In these ways, and more, the coenzymes created in the body from the B vitamins help many of the reactions of life to take place, and without these coenzymes life could not exist. Hence the importance of the B vitamins themselves, and any deficiency could be disastrous to the metabolic processes that generate energy and keep you alive. It is not just the energy needed for exercise and normal human activity that will be compromised, but also that which keeps the heart beating and your diaphragm moving to allow you to breath.
Without a doubt, a Vitamin B supplement is one of the most valuable of all the vitamin supplements, and they are available in many forms. You might also find some of the B vitamins in their coenzyme form, though some of them may be unstable. However, whatever form they are taken in, Vitamin B complex should be one of the first on your vitamin supplement shopping list.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1784) Artichoke Leaves Provide Stimulating Digestion Benefits
Date:
February 22, 2008 10:46 AM
The leaves from the plant of this familiar food are found to be beneficial to our digestion and metabolism, potentially reducing cholesterol. The artichoke has long been eaten as a vegetable, and has been ascribed many beneficial attributes. Artichokes were cultivated in the ancient Mediterranean and enjoyed great popularity in the thriving Roman Empire. From then until its mid-16th century reemergence, the artichoke hovered in sporadic obscurity. Greek philosopher Theophrastus, a recognized naturalist, wrote of artichoke cultivation in Sicily and Italy around 300 B.C. Several centuries later, physicians and naturalists in Greece and Rome collected and recorded information on the health remedies resulting from intake of the artichoke and its preparations. The artichoke was also considered an aphrodisiac and a delicacy; to this day that estimation still remains. Along with possessing a pleasantly robust and slightly bitter flavor, the fleshy lobes of the artichoke contain vitamins A and C, dietary magnesium, folic acid, fiber, as well as potassium and manganese, among other essential nutrients. But the story doesn’t end there. The oft-thrown away serrated leaves of the artichoke plant, a member of the thistle family, contain even more health benefits than their edible counterpart. What most people are familiar with is actually the edible flower bud of the artichoke plant. The plant’s leaves contain two key substances with health-giving attributes, the main one being cynarin. What is fascinating about this compound is that fresh artichoke leaves only contain trace amounts of cynarin. During the extraction and drying process, the levels rise due to chemical changes that occur during the process. Artichoke leaf extract contains beneficial levels of this compound that provides maximum benefit when ingested. Before more potent pharmaceuticals were developed by drug companies, synthetic cynarin preparations were prescribed to patients with high cholesterol. Cynarin stimulates bile secretion in the liver and gallbladder; working as a digestive aid to break down fats and cholesterol. Additionally, increased bile production assists the digestive track in eliminating toxins from the liver. Bile is formed in the liver, created by the combination of cholesterol and triglycerides. Often times these two terms are considered negative, but not all cholesterol is bad cholesterol. Some forms are necessary for normal body function. Once the bile is formed in the liver, it is stored in the gallbladder. Bile not only works to eliminate toxins, it also emulsifies fats to allow them to be digested and metabolized. Without bile the digestive track would be a disaster, and the body would be unable to absorb fat soluble vitamins. The process by which artichoke leaf extract is thought to lower cholesterol levels is made up of two parts. More bile means the liver has more power and efficiency in breaking down and eliminating cholesterol. In addition to the increased ability to get rid cholesterol, artichoke leaf extract has been shown to inhibit cholesterol production in the liver. This second attribute is thought to come from the levels of luteolin in the extract. Luteolin, a flavonoid, is an antioxidant efficient at fighting free radicals and reinforcing the functions of the immune system. Additionally, luteolin has been shown in studies to increase carbohydrate metabolism and prevent LDL-cholesterol oxidation. Medical science is only beginning to reveal the details of how artichoke leaf extract works to improve cardiovascular and digestive health, while ancient physicians and traditional healers had a hunch all along.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1722) Eighty Seven Percent of All Type 2 Diabetes Can Be Prevented Naturally
Date:
January 24, 2008 05:06 PM
It is a fact that almost 90% of Type 2 diabetes can be prevented by attention to diet and the use of specific supplements. However, before having a look at these possibilities, we shall first have a look at what type 2 diabetes is so that the means of prevention can be better understood. Diabetes is a condition, not a disease. It cannot be passed from one person to another, and there is evidence that it is hereditary since it tends to run in families. In the past it tended to develop later in life, although the modern lifestyle appears to have made it more common now in children and young adults. Diabetes occurs when the level of glucose in your blood becomes higher than it should be. The reason for this is twofold: either the body produces no or insufficient insulin or it cannot use the insulin that is produced. Sugars and other carbohydrates are metabolized to glucose that is the body’s source of energy. The parts of your body that do this are the mitochondria that are contained within your body cells, and the hormone insulin is essential in allowing this to happen. When the concentration of glucose in your blood reaches a certain level, the pancreas secretes insulin into your blood. The insulin is synthesized in special cells called the islets of Langerhans, after the person who discovered them. Also produced is glucagon which is also secreted into your bloodstream, and the glucagons and the insulin work together to ensure that your blood glucose levels remain stable (when everything is working correctly). Glucagon is secreted when your glucose levels are low, and its presence in the bloodstream stimulates the conversion of the emergency energy store in the liver (glycogen) to glucose in order to maintain this stability. Insulin, on the other hand, is released after you have consumed a meal, and your glucose levels are high. What insulin does is to stimulate the cells of your body to convert glucose to energy and either use it immediately, or store it as glycogen for use later. By means of these two substances, the level of glucose in your blood is maintained at safe levels – normally. If something happens to the supply of insulin, then the blood sugar level will continue to rise until the bloodstreams contains too much glucose, a condition known as hyperglycemia. The symptoms are excessive thirst, a frequent desire to urinate, fungal infections or thrush around the genital area (due to yeasts and sugar fermentation), and various others such as mood swings, cramps, dizziness and a feeling of tiredness and weakness. Type 1 diabetes occurs when the body produces no insulin, and the only possible treatment is continual insulin injections. Type 2 diabetes is defined in two ways. Either your body does not make enough insulin for your needs, or the cells in your body cannot use the insulin produced properly. It is Type 2 diabetes we are concerned with here, and that we shall be exclusively discussing. With Type 2 diabetes, insulin shots can be provided, but there are other factors that can also help to resolve the problem. Before discussion treatment or prevention, you should be aware of the complications that Type 2 diabetes can lead to. Hyperglycemia is not common with this type of diabetes, but it can develop. If it does then it can be a life-threatening condition needing a rapid injection of insulin into the bloodstream Symptoms prior to the critical stage are drowsiness and dehydration, although as stated, this is more commonly associated with Type 1 diabetes where regular insulin injections is the normal treatment. Longer term complications of Type 2 include kidney damage, hardening of the arteries, eye problems, impotence and problems with your circulation. Nerve damage can also occur, and it is important that you avoid these by changing your diet and lifestyle. These problems occur if you have had high blood glucose levels over a long period of time, and you therefore have time to take the steps necessary to avoid them if you start now. The same steps will also help you to avoid the condition from occurring. So what are these steps you should take? The first is to look carefully at your diet. A healthy balanced diet is essential if you are to beat your condition naturally and avoid the potential longer term side effects. Diabetes is associated with the overweight and obese. That is not to say that only these people become diabetic, but the majority are. Most people with Type 2 diabetes are overweight, and although around 65% of Americans are overweight or obese, a considerably higher proportion of those with Type 2 diabetes are overweight. The first and obvious action to take to avoid this type of diabetes would therefore be to lose weight, and adopt a healthy diet that is free from junk food, trans fats and alcohol, all of which contribute to obesity. The next is to look to your blood pressure and keep it normal, and also to keep your low density lipoproteins (LDL) low. These affect the propensity for your blood cholesterol to deposit in your arteries, especially if they are oxidized by free radicals. A good antioxidant content is therefore recommended in your diet. Although blood pressure and high LDL levels do not directly contribute to diabetes, they are risk factors that could increase the risk to your health if you are diabetic. You should eat a diet that is high in whole grains and fiber, and eat lean meats and fish rather than fatty foods. Stick to complex carbohydrates that metabolize to glucose slowly and steadily, rather than starchy foods that produce a sudden sugar rush that will give you problems and could promote Type 2 diabetes in those that are prone to it. Specific supplements that you could take include chromium picolinate that can not only be used to treat existing diabetes patients but also to reduce your chances of developing Type 2 diabetes. Studies involving the use of chromium picolinate on patients with this type of diabetes have been very positive, resulting in reduced blood sugar, lipid and insulin levels. The optimum dosage is around 500 micrograms twice daily. Such treatment has been shown to both prevent and reverse Type 2 diabetes. Magnesium is another specific supplement that studies have suggested can lower the risk of developing this type of diabetes. Magnesium rich foods have also been found to be effective, and the fact that a magnesium deficiency can lead to diabetes supports the findings that its use can help to prevent it. Green leafy vegetables such as spinach, and beans nuts and seeds are generally rich in magnesium. Vitamin D can also help protect against the development of diabetes. Although the research is relatively new, it has been established that the cells that produce insulin are affected by a lack of vitamin D in the blood, and low levels of vitamin D can also led to insulin resistance. If you spend more time out in the sun, you should have less chance of contracting Type 2 diabetes, although you could also take a supplement.
Although Type 2 diabetes is not as serious as Type 1, no form of diabetes is desirable to have, and ultimately both types can be extremely serious. You should do what you can to avoid diabetes, and Type 2 is easier to avoid then Type 1. Diet, weight and supplementation as described above will all help to avoid contracting this condition, so follow the advice, especially if you are overweight and have a sweet tooth.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1706) Which Form Of Calcium Is Best For You?
Date:
January 15, 2008 05:10 PM
There is no warning signal that lets you know if you have a calcium deficiency. Actually, a calcium deficiency is usually undetectable until damage that is irreversible has already occurred. A calcium deficiency is extremely hard to detect because the calcium level in the blood may seem to be normal, even if extreme cases of deficiency are actually occurring. This is because the body has a calcium bank, which can be found in teeth and bones. Calcium is needed in order to control muscular contractions such as the heart, blood-clotting, transmission of nerve impulses, and other requirements which take priority. You may not know for sure whether you have calcium deficiency until you experience loose teeth, receding gums, or a bone fracture. At this point you will realize how brittle and chalky your bones have become. There is no known cure for osteoporosis, and it seems to be affecting people at younger ages more and more. The progression towards this illness takes years, but it is going on unnoticed in a great percentage of our population right as we speak. There are many reasons why calcium deficiency is so widespread. First, calcium is not easily absorbed, as no more than 10-20% of what is found in foods is actually consumed and metabolized. This is because a meal that is high in fats can form insoluble calcium soaps which cause calcium to pass through the system without being absorbed. Also, the calcium in certain vegetables can actually be inhibited from releasing by oxalates that are found naturally in foods such as rhubarb, kale, spinach, broccoli, grains, and cereals. Furthermore, vitamins A and D must be present in the body in order for absorption to occur. Additionally, calcium requires an acid environment for absorption, which is a huge problem for older people who have less production of digestive acids. More so, amino acids are needed for the formation of calcium-amino acid complexes and magnesium and phosphorus must be present in a precise ratio’s. Without all of these factors, you can lose a lot of the benefit, no matter how much calcium you are taking in. A great variety of calcium supplements can be found in your health food store. These supplements can range from a simple calcium carbonate to bone meal, dicalcium phosphate, dolomite, calcium lactate, calcium gluconate, and many others. Although they all contain calcium, they vary in the amount of actual calcium content from 40% in calcium carbonate to 9% in calcium gluconate. Calcium carbonate has the highest percentage calcium per gram, but it acts as an antacid which makes this supplement somewhat useless since calcium can only be absorbed in an acid environment. Acid breaks down the bonds between the calcium element and its bonding partner like carbonate or amino acid chelate. Calcium Carbonate has a carbon bond the strongest bond of its kind; this makes it extremely unwise for those people who are older or suffer from a digestive acid deficiency. Calcium carbonate that is derived from oyster shells is no different from any other form. However, oyster shells carry an additional risk of being contaminated with naturally occurring heavy metals found in the oyster bed environment. Calcium phosphate is probably the best source of calcium, since the principle calcium in the body is actually calcium hydrogen phosphate which is easy to digest. Whether you choose calcium carbonate or calcium citrate, ask your local health food store which calcium is best for you depending on your age and whether you have a digestion disorder or not. With poor diets and lack of exercise, calcium supplementation is a must for most people. Have you had your calcium today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1689) Fight Acne by Eating Right to Lower Blood Sugar Levels
Date:
December 24, 2007 02:11 PM
If you are a teenager a cure for acne will likely be first on your list after finding a boyfriend or girlfriend, and most of us who have been teenagers can probably remember the misery that our perception of our looks gave us. There have been many theories as to the cause of acne, and it is highly likely that there is more than one. The basic reason for the appearance of acne is that oils, dead skin cells and bacteria block the pores of the skin to form a variety of different types of pimples or spots, such as whiteheads, blackheads and pustules than can be irritating or painful. They can also be very unsightly, affecting the face, neck and sometimes the chest and back. Studies have indicated that acne is caused by the over-production of sebum, a fatty oily substance secreted by the sebaceous glands of the skin to keep it supple and lubricated. If this is excessive, the sebum can block the pores causing blackheads, and become infected causing acne. So what causes this excess production of sebum? There are theories that it could be due to high insulin levels in the blood. High insulin levels are promoted by high blood glucose levels the more blood glucose in your blood then the more insulin your pancreas produces to help covert it into energy. Higher insulin levels are also associated with high levels of insulin-like growth factor 1 (IGF-1). The result of this is an increase in androgens (male hormones), specifically dihydrotestosterone (DHT), metabolized from testosterone. This in turn causes an increased production of sebum leading to acne. The complete chain, therefore, begins with increased levels of glucose in your blood and ends in acne. In order to prevent acne you would have to break this chain anywhere in its sequence, and the only viable place to do this is at the beginning reduce your blood glucose level. In order to achieve this you would have to determine what foods you are eating that could cause an excessively high level of glucose in your blood. Glucose is metabolized from carbohydrates, ranging from complex carbohydrates to refined sugar. However, those that you should try to avoid are the refined carbohydrates such as pasta, white bread, rice and sugar. These are what are known as the high glycemic index foods that can cause a sharp rise in your blood glucose levels when consumed. The complex carbohydrates take longer to be metabolized and are not so prone to producing sudden increases in your sugar levels. These lead to more sustained and gradual increases in blood glucose that demand a steady insulin supply, rather than the sudden increase that can lead to acne. Such foods include high fiber whole grains, oats and the like. Studies have indicated that twelve weeks on a diet of low glycemic index foods resulted in a significant reduction in acne symptoms when compared to a control that did not change their diet. It therefore seems likely that your nutrition can affect your acne, and that changes in your diet could lead to a significant long-term reduction in acne symptoms such as pimples, pustules and other types of lesion. The same studies also proved a reduction in the androgen levels of those on the complex hydrocarbon diet compared to the controls, and also greater sensitivity to insulin. However, the test group also experienced a significant weight loss, and it was not conclusively proved whether the reduction in acne symptoms was due to the reduction in blood glucose levels or to the weight loss. However, the result is in accordance with the insulin and androgen theory, and it is known that diabetes is connected with obesity, so the two might in any case be related. Acne, diabetes, and weight are all related to your blood sugar level, which is in turn related to diet and carbohydrate intake. Although a low glycemic index diet is suggested, such a diet is not easy to apply properly, and a dietician could help you here. Persistence is the name of the game, and you will not see instant results. Note that the tests referred to above were over twelve weeks, and this is likely the minimum period you will need to stick to your diet. However, the minute you break it, and revert back to simple carbohydrates, your problem will return. There is no sudden cure, rather a continual dietary approach to the prevention of the condition. Acne is not a disease that you can catch and cure. It is a condition created by lifestyle and diet, and can only be controlled rather than cured until you grow out of it in your late teens or early twenties, although many people suffer from acne until later in life. Your diet should include plenty of fresh fruit and vegetables, whole grains and cereals, brown rice, fish, eggs and lean meats. You should avoid saturated and trans fats, and eat unsaturated fats and oils, with plenty of omega fatty acids, vitamins and minerals for a good skin and good health. Exercise will help by improving the blood flow to your skin. You can also help your condition by taking some specific supplements. Saw palmetto and zinc will help to reduce the levels of testosterone in your blood, and vitamins E and B6 are also believed to help. Selenium, pantothenic acid and essential fatty acids are other supplements that can help with acne, but your best bet is to discuss your condition with a naturopath or somebody trained in the use of natural remedies and supplements with your condition. Many swear by tea tree oil, although treatment has to be prolonged over a length period before it becomes effective, but you might prefer this to one of the chemical testosterone blockers that can be prescribed for acne in certain cases. Overall, acne is not a serious condition but can be disfiguring. Although you can seek medical help in the event of serious attacks, your recommended treatment initially is to eat plenty of healthy foods low in simple carbohydrates, to take the appropriate supplements and nutrients to keep you healthy and to take plenty of exercise to maintain a good blood supply to your face. In these ways you can reduce the number, depth and lasting effects of acne pustules, and in many cases clear the condition altogether.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1680) Natural Sweeteners: Which One Should You Take?
Date:
December 09, 2007 03:23 PM
There are many natural sweeteners to choose from if you want to avoid sugar, but don’t want any of the artificial sweeteners over which there are a few questions. You can choose from xylitol, luo han, stevia and others, but before discussing these, let’s have a look at the problems with sugar, artificial sweeteners and the American sugar industry. Sugar as most people know it originates either from sugar cane or sugar beet, though by far the biggest American industry is in the cane. There are many different types of sugar, though that obtainable from cane sugar is sucrose. Sucrose is a disaccharide and carbohydrate, stored by plants as a reserve energy source to be used when needed. Humans cannot directly use sucrose, and it is metabolized in the body to glucose which needs the hormone insulin to help convert it into energy. Insulin is produced in the pancreas, and a lack of it, or the body’s failure to use it properly, is referred to as diabetes. There are two types of diabetes: Type 1: A total lack or deficiency of insulin due to the pancreas producing insufficient quantities of insulin, or even none at all. This is often seen in young people and is generally cause by the immune system attacking the insulin-producing sells in the pancreas. The treatment for type 1 diabetes is to introduce insulin to the blood, normally by means of injections, plenty exercise and the adoption of a high carbohydrate low fat diet. Type 2: This is strongly associated with obesity and weight, and is due either to insufficient insulin production by the pancreas (but not as deficient as for Type 1 diabetes) or an inability of the cells of the body to properly use insulin. Type 2 diabetes does not always require insulin injections, and can be treated by exercise, diet and weight control. However, there are occasions where insulin injections are also required. It tends to affect people older than those with Type 1 diabetes and 90% of cases are of this type. Both types, however, are connected with an excess of glucose in the blood, into which most sugars are converted. A diet low in sucrose will go a long way towards helping people that suffer from either type of diabetes, and control of carbohydrate intake should include a reduction in the intake of sucrose in the form or beet or cane sugar. This accepted, then if you need a sweetener, a saccharide free natural sweetener would appear to be the logical choice. You could opt for a synthetic sweetener, but they also have their problems. There is evidence that saccharin could be a carcinogen, and ‘aspartame’ disease is not a myth. The other artificial sweeteners also have sufficient questions that natural sweeteners would appear to be the obvious choice. But which? That is the question. Let’s have a look at some and check out their pros and cons. The first is Stevia. This is a South American herb that is 400 times sweeter than sucrose and yet is very low in calories and does not affect diabetics. Used throughout most of the world, it has not been approved by the FDA as a food additive due mainly, it would appear, to lobbying by the American sugar corporations. This is understandable, since mass substitution of sugar by stevia in processed foods is entirely possible, but would cost the sugar corporations billions. However, it is available to purchase from health food stores, and does not appear to possess the problems that aspartame does. Unlike that sweetener, it can be used in baking and cooking, and is ideal for diabetics and people suffering from yeast infections such as candida. Such infections are aggravated by sugar in the colon, since yeasts love sugar, but they cannot survive on stevia. The safety of stevia has been proven through hundreds of years of popular use without any problems. However, there are others. Luo Han Guo is a sweet Chinese fruit of which extracts are marketed as a natural sweetener. The plant it comes from is the Momordica grosvenori, a member of the cucumber squash family that grows in the mountainous areas of southern China. The sweeteners it contains are called mogrosides that are terpene glycosides, of which there are five different forms, the main one being termed mogroside-5. The extract is available in the form of a powder consisting of around 80% mogrosides, and possesses around 250% of the sweetness of sucrose. This, too, can be used in cooking; because it is stable to heat and contains about 2% of the calories of ordinary sugar (one half teaspoon is equivalent to 25 teaspoons sugar). You can help 50 medicines go down for the same calories of getting one down using sugar! Not only that but, like stevia, there are no known side effects. It has been used for many centuries in Chinese medicine in the treatment of gastrointestinal conditions and conditions of the respiratory tract. Unlike natural sweeteners, luo han has been found to be useful in helping to manage diabetes since it does not cause insulin levels to rise and are not involved in energy production, so have no effect on your weight. The mogrosides from luo han are also under study as inhibitors of certain tumors, and might be able to inhibit skin tumor growth. Other possible medical advantages include helping to reduce atherosclerosis and heart disease, so would appear to be a useful sweetener to use in your coffee! Finally, xylitol. It was during World War II that Finnish scientists rediscovered xylitol that had been previously used in Germany as a sweetener in the late nineteenth century. The sugar shortage resurrected this substance that can metabolize without the need for insulin. Xylitol is a substance that is found in some fruits and vegetables and also in corn cobs. In fact, it is a product that appears in animal metabolism, and so is perfectly safe. It is known to help support the immune system, and to help reduce the effects of aging. It possesses antibacterial properties due to its 5-carbon ring and has been approved by the FDA. Xylitol can replace sugar in most of its domestic uses, including in baking and as a natural sweetener. It is also used extensively in chewing gum as a sweetener that does not cause dental cavities due the acid caused by bacterial attack on the sugar. However, one use to which xylitol cannot be put, nor any of the other natural sweeteners mentioned here, is in fermentation. Try these for your wine or beer and you will be very disappointed at the low alcohol level of your brew! This is also, however, one of the benefits of xylitol: it cannot feed the yeasts that cause candida or any other yeast infection. Although it is a saccharide, it is the same as the others in this respect. So, which of these natural sweeteners should you take? The choice is yours since each has its own benefits with very few disadvantages and certainly no recorded side effects that we know of. Use stevia for superior sweetening effects, and make up a concentrated solution of it in water for your cooking. Use luo han if you have gastrointestinal problems, and use xylitol if you want fresher breath and to protect your teeth. Use none for brewing or winemaking, and use any of them if you are diabetic. The choice is yours. These sweeteners are available at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1651) Loose Weight By Cutting Dietary Fat Absorption
Date:
December 08, 2007 06:24 PM
You can lose weight by cutting dietary fat absorption, although in order to understand the need for this you have to appreciate the effect that fat has on your weight. Not only fat, but any form of calories. The word ‘calorie’ appears to have a bad press, and there have been a lot of ill informed comments made about calories and whether calorie controlled diets are effective or not. Quite frankly, it is all said in ignorance. Whether you agree or not, the calorie is a measurement of energy and the calorie content of foods is what is calculated to be the energy value of these foods. Once inside your body, that energy is either used up or converted to body mass. It is not necessarily converted to fat, since that extra weight could be in the form of muscle tissue. However, it is converted to body mass and so you can put on weight. The basic equation is that if you take in more energy than you use, then you add weight, and if you use more energy than you take in, then you lose weight. It is slightly more complex than that, but it is basically true. That does not mean that if you eat a pound of dripping (the fat that drips off cooking meat) you will add a pound of weight. It is the calorific value of the dripping in terms of energy, whether measured in calories or in joules, that is the relevant factor, and if that is 4000 calories, which is about average for various types of dripping, then if you use up 4001 calories in exercise, you can safely spread your pound of lard on toast and eat it without putting on weight (you will have also to use up the calories in the toast). It is the calorie equation that is important, and if this is negative then you will lose weight. You have to: it is a law of science! Whether your calories are in the form of cookies, candies, avocados (loads of them) or dripping, it is all the same. A meat calorie is the same as a vegetarian or vegan calorie. If you eat more than you use you put on weight. Different foods contain different quantities of energy, or calories. If you buy a Big Mac you eat 570 calories, and 5 from your Super Pepsi. If the guy next to you has an English Muffin, he will have 140 calories. However, if he then goes home and slouches on the sofa watching TV and you go to the gym for a serious workout, he is liable to put on weight and you lose it. It’s all in the equation! However, you don’t just use calories in exercise. Your metabolism is also important. In fact 65% - 75% of the calories you use in a day are used up by the body at rest: the metabolism that takes place 24/7 to keep you alive. The heartbeat, breathing and brain activity for example, all use up energy. So not all is doom and gloom, and you can burn up these calories even while you are sleeping. However, there is another way to prevent the fat you eat from turning into weight. (Incidentally, if you exercise a lot, that weight will likely be in muscle mass, but if not then it will certainly be fat). You have a clue to the way that can be done in the first sentence of this article: ‘dietary fat absorption’. If the fat is not absorbed into the body, then it is not available to be metabolized into body fat. It will pass through the body unchanged. It is not the fat you consume that makes you gain weight, but the amount of that fat absorbed through your intestines. But how is it possible to selectively prevent the fat in your diet from being emulsified by the bile and absorbed through the intestinal wall? By means of chitosan. This is a fiber that absorbs part of the fat from the food you have eaten and hides it away from your digestive system. It cannot be broken down into sugars and then into fat to add to your unwanted weight. However, because it works after your meal, you get to eat what you want – that ‘finger lickin’ good’ stuff you love, but don’t suffer the consequences of failing to exercise to work it off. It’s like you just ate lettuce without the fried chicken with the crispy fatty skin. So what is this miracle substance, chitosan? Biologists would recognize the name as being associated with chitin, the acetyl-glucosamine polymer that forms the carapaces, or shells, of crabs, lobsters and other marine shellfish. Chitosan is formed by deacetylating the chitin and is mainly used to enhance the growth of plants, and also as a filtration aid. So what does it do to help to remove some of the fat from your diet after you have eaten it? The mechanism by which it does this is not fully understood, and in fact is still disputed in some quarters. However, the proof of the pudding is in the eating and it appears to act according to the claims. There are two possible mechanisms, one of which is connected with the deacetylation of the chitin molecule. Because of this, the resultant chitosan molecule has cationic groups on the polymer chain. Cations are positively charged, and can react with acids, not the least of which are the bile acids that break down lipids (fats) to render them into a form suitable for absorption. It is possible for the chitosan to react with the bile acids and prevent them from breaking down the fats into a condition that enables them to be passed through the intestinal wall. However, it has also been proposed that dietary fibers work by increasing the thickness of the boundary layer of the intestine through which the fats would have to pass. This would have the effect of reducing the lipid uptake. It is also possible that since chitosan is a fibrous substance, it attracts the fats through its charge and absorbs them into a swelling ball of fats and fiber that is not only impermeable by the bile acids, but also passes through the intestinal tract unchanged and eventually excreted. In fact, there is not proof for any of these projected mechanisms, and all are theoretically possible. The fact is that it appears to work, but must be taken for several weeks for the effects to be noticeable. It is possible to lose weight by dietary fat absorption, and whatever mechanism is used by chitosan, it is well worth trying if you like your fatty foods but also want to lose weight. Combine chitosan with a good exercise regime and you might find that you can control your weight whatever you eat. Chitosan is available over the counter at any health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1650) Stevia: Sweeten Your Life With Out The Weight Gain
Date:
November 13, 2007 02:55 PM
It is possible to sweeten your life with stevia, and without any weight gain, since it as exceptionally sweet herb. In fact it is member of the sunflower family, and is native to parts of South and Central America where it has been used as a sweetener since time immemorial. Also known as sugarleaf, it is a commercial crop, and is available as a dietary supplement. Extracts of stevia have been found to be up to 300 times as sweet as cane sugar, although does not metabolize in the body to glucose. In fact it is thought to enhance the glucose tolerance of some diabetics, and can be used by people suffering from that condition as a natural sweetener, thus dispensing with the need for artificial sweeteners. It is also useful for those on diets, especially carbohydrate controlled diets, and any other sweet-toothed person wanting to lose weight and still enjoy their favorite drink or desert. Many recipes have been published using stevia for the preparation of delicious sweets. So why is stevia so sweet and what other uses does it have? Basically the sweet taste comes from glycosides, which are molecules in which a sugar is bonded to another molecule. The two main glycosides in stevia are called stevioside and rebaudioside. These are formed through glucose combined with the diterpene steviol in different ways, though some minor glycosides also contain rhamnose. Although they contain glucose, the glucose is not released into the bloodstream during digestion and the subsequent biochemistry. Japan began the cultivation of the plant in the 1970s rather than produce artificial sweeteners that were suspected carcinogens (saccharin and cyclamate). Japan is now the world’s biggest consumer of stevia, even being used in the Japanese Coca Cola plants. Around 40% of Japan’s total sweetener volume is stevia. However, apart from its use as a natural alternative sweetener to sugar, stevia has specific properties, already alluded to, that renders it of particular attraction to certain groups of people, and we shall now take a closer look at these. Insulin is a hormone produced by the pancreas that is essential to regulate the glucose content of the blood. It stimulates the cells of the body to take in blood glucose and convert it to glycogen that can be used for energy. Without insulin the blood sugars would increase in concentration without regulation leading to very serious health issues that would eventually result in death. Diabetes is a condition in which the body either does not produce sufficient insulin, does not use the insulin it produces properly, or produces no insulin at all. Hence, a sweetener that did not exacerbate this situation by being eventually metabolized to glucose, as most sugars are in the body, would be of great benefit to diabetics. This is exactly what stevia is. It is a very powerful sweetener, 250 – 300 times sweeter to the taste-buds than sucrose, normal table sugar, and it does not metabolize to glucose. It is heaven-sent sweetener for diabetics that have a sweet tooth. It is very safe for them and has been consumed for centuries without any side effects. In fact, studies have indicated that stevia might even regulate the pancreas and help to stabilize the levels of blood glucose in the body, rendering it an effective and safe supplement for those suffering from hypoglycemia (excess blood sugar), diabetes and candidiasis, a yeast infection that thrives on sugar. Apart from that, stevia is also popular with those who are on a calorie controlled diet – or any other diet for that matter, since an excessive sugar intake invariably leads eventually to weight increase. The 21st century western diet is drowning in sugar, with up to 10 spoonfuls of sugar in every small bottle of cola. There is sugar in cookies, hot dogs, bread, soy sauce, ketchup, cans of beans and peas, and even sugar in cigarettes, though that is the least of the health worries there! For the first time in history, there are now more overweight and obese people in the world than hungry people, yet the sugar corporations claim that there is no scientific proof that sugar leads to weight increase. Worldwide, diabetes kills 6 people every minute, and obesity caused by the consumption of too much sugar leads to Type II diabetes. It had been shown that fructose is a major player in that corn syrup (fructose) is contained in many soft drinks and foods. One of the major problems with refined sugars is that they contain nothing but pure carbohydrate. All the vitamins, minerals and other nutrients have been removed, so that when they are consumed, your body has to provide these nutrients needed to metabolize the sugar to glucose and then to energy. Humans cannot live on sugar alone, and in fact you are better drinking water than corn syrup or cane sugar solutions since at least water does not make demands on your existing nutrient store. It was noted in 1929 by Sir Frederick Banting, one of those scientists credited with the discovery of insulin, that there was a significantly large proportion of diabetes among the sugar plantation owners that ate large quantities of refined sugar, whereas there was none detected in the cane harvesters who were able to chew on only the raw cane. The raw cane contains the minerals and vitamins needed to metabolize the sucrose. Stevia is a potential answer to this problem, and it is such an obvious one that there are a lot of politics regarding its use. The big USA sugar corporations will undoubtedly be opposed to it, and the FDA has refused to allow its use as a food additive, only as a dietary supplement, yet its use in Japan has been very successful. It is also used throughout East Asia, including China, Korea and Taiwan, and also in South America, Israel and some areas of the Caribbean. It is available as a green powder in its crude form, and also brownish syrup redolent of licorice, but also as a more refined white powder that is likely best used as weak solution due to its sweetness. It is totally free of calories; this may come as a surprise to many since it tastes so sweet. It is an excellent sweetener for children’s drinks since it does not cause cavities: unlike sugar it is not degraded by bacteria to produce the corrosive acid that eats into the enamel. It does not metabolize to a burst of energy that is practically addictive, since that generally then leads to tiredness and the need for more sugar to make up for it. Stevia does not cause diabetes in any form, is not a food for yeast and it is beneficial to the pancreas. In short, it is a completely safe food supplement that has been used for centuries without ill effect, and if you want to prevent yourself from adding weight and protect against the possibility of Type II diabetes in particular, then stevia should be your sweetener of choice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1630) Take Charge Of Your Health With Herbal Bio-Identical hormones
Date:
November 04, 2007 03:17 PM
Bioidentical hormones assist women in overcoming acute menopausal symptoms, while improving skin. They help by strengthening bones, keeping the mind sharp, promoting energy and well-being, and helping to preserve vaginal tone and resist vaginal dryness. In men, these hormones add energy and vitality, while improving muscle tones and mental sharpness. Bioidentical hormones (BHRT) are exact duplicates of the hormones that are produced by the body. However, they are much more easily metabolized by the body into safe forms of estrogen than their counterparts, which stimulate toxic metabolites. When they are used in physiologic amounts, bioidenticals carry much fewer risks than synthetic hormones. However, despite the fact that research supports their use and proves them safe alternatives to prescription drugs, few physicians are actually using these hormones in their practices. Those patients, who wish to address menopausal and andropause symptoms, or to achieve lifelong hormonal balance in order to prevent illness, often do not know where to go to find a comprehensive bioidentical hormone replacement program. Instead, they read whatever they can to formulate a plan and purchase various products that are available over the counter, often spending precious time and money on programs and products that don’t do what they’re expected to do. One of the most common errors among people is putting together a program based solely on symptoms instead of first checking hormone levels. Symptoms may overlap from one hormone pattern to another. If you try to replace or augment specific hormones without having an accurate test of the levels first, your results will seldom be good. If your doctor is prescribing transdermal hormones, make sure to do a saliva self-test to measure your hormones levels as it is much more accurate and revealing than other types of tests. You can submit your samples to Mead Labs, where you will actually receive a telephone consultation from a health professional to interpret your results followed by a program of products prescribed especially for you from one of their medical professionals. With your own results, you can learn a lot about the exact state of your hormones instead of blindly guessing from symptoms which may be similar. For example, men may not need testosterone shots or transdermal patches, as the results may show estrogen dominance. The answer for this is not adding more testosterone, because the man could be converting testosterone into estrogen, but instead a program including special herbs and nutrients may be much more beneficial. No matter your gender, your health professional at Mead Labs will design a safe and effective program based solely on bioidentical hormones, herbs, and nutrients first. In the past years, when prescription, non-bioidentical HRT was used by any women with menopausal symptoms, there was no testing to find out what kind of imbalance was actually occurring. Proponents of BHRT are trying to ensure that this method of prescribing the same combination and amounts of medications to everyone is not used with natural hormones. Because hormone profiles and levels can vary significantly from person to person, even those people in the same gender, testing hormones levels and obtaining recommendations from a medical professional who is experienced in BHRT are the key points to ensure you benefit from this therapy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1617) Coconut Oil May Help Promote Healthy Thyroid and Digestive Function
Date:
November 01, 2007 09:49 AM
Coconut is extracted from coconuts, the coconut palm often being called the tree of life and for good reason. However, its benefits were lost to America for many years due to the politics of the vegetable oil industry claiming that all saturated fats are bad. This is not based on scientific or medical fact, and coconut oil was recently rediscovered in the USA, and the health benefits enjoyed by the rest of the world are once again available to Americans. Coconut palms grow in most tropical climates such as Southern California and Florida, the Philippines and the Caribbean. Refined coconuts oils are mass produced and much of the beneficial nutrients are lost by the refining process. Virgin coconut oil is by far the better form, though is a slower process. It is generally obtained by shredding and dry milling the meat, and then cold pressing to produce the milk. The milk is fermented for a day or so and the separated oil collected. Such oils are analyzed to contain over 50% lauric acid and high levels of phenolic antioxidants. Much higher than from refined oils. It is said to be the healthiest oil on earth. So why did the American authorities legislate against its use? It is because of the bad press received by saturated fats and oils. You can have saturated, monounsaturated and polyunsaturated fats. The majority of the fats and oils in our diet are composed of long chain fats and oils. The chain length refers to the length of the hydrocarbon chain, whether saturated or unsaturated. It is long chain saturated acids that are bad for your cardiovascular system, and that should be avoided. However, there are also short chain and medium chain fatty acids that are more easily metabolized by the body. Coconut oil consists predominantly of medium chain fatty acids that help to protect against heart disease and cholesterol rather than promote it. The highest levels of medium chain fatty acids are found in coconut oils and palm kernel oils, and these are far more nutritious than the saturated long chain fatty acids found in animal fats and just about all vegetable fats. The main MCFA in coconut oil is lauric acid. Lauric acid is generally regarded as being responsible for the vast majority of the health benefits of coconut oil. The only other source of this fatty acid other than coconut oil is in human breast milk. After absorption, lauric acid is metabolized into monolaurin that is the monoglyceride used by the human body to destroy viruses and microbes, and attack the fat coated viruses that cause such diseases as HIV. It destroys flu viruses, a number of dangerous bacteria and protozoa such as giardia lamblia. However, let’s have a look at some of the lesser known effects of coconut oil, such as its effects on the thyroid. Anything that blocks the efficient operation of the thyroid and secretion of the thyroid hormones can lead to excess estrogen in the body that can contribute to excessive blood cholesterol. There is a body of evidence that polyunsaturated fats and oils, such as soy, can have this effect is many people. When coconut oil is used instead, the medium chain fatty acids do not have the same effect, and those that are affected frequently find that their thyroid problem is cured and their blood cholesterol reduces. This is not to infer that all hypothyroidism can be cured through the use of coconut oil, only those cases caused by consumption of excessive amounts of polyunsaturated fats. Although this is refuted by some medical practitioners that are against the use of supplements in general, it has been supported by medical evidence. Coconut oil is also good for the digestion, and helps the cure of many digestive problems including Crohn’s Disease. It helps to build lipoproteins, fats and bile in the liver, the latter being essential for digestion. It helps to create a much healthier digestive tract that makes for generally better digestion and more efficient use of the foods you eat. Absorption of the nutrients is maximized and you feel altogether better in yourself when you take a small amount of coconut oil daily. You can have sugar cravings for a number of reasons, and taking coconut oil can reduce these quickly and effectively, irrespective of their cause. The medium chain fatty acid breaks down and is rapidly metabolized to glucose thus providing a source of the energy your craving is telling you that you lack. It is very useful in reducing sugar cravings without you having to eat excess sugar that can create yeast problems. If you replace the fats you are currently eating with coconut oil, it will not only act as an appetite suppressant but can also help you to lose weight. The fatty acids in coconut are absorbed immediately and converted to energy thus reducing your immediate need for food and hence your appetite. If you eat the saturated fat in coconut oil rather than the polyunsaturated fats in vegetable oils, then you can lose weight. Many of the benefits of coconut oil are due to the speed with which the lauric acid is absorbed and metabolized in comparison to the long chain polyunsaturated fats. It is the chain length of the hydrocarbon tail that is important here rather than the number of double bonds in that chain that determines the degree of unsaturation. Make sure that it is virgin coconut that you use since that is the most nutritious form. Do not be misled by labels claiming the contents to be extra virgin oil, since that is a term borrowed from the olive oil industry, and there is no such thing as extra virgin in relation to coconut oil. Never use refined coconut oil since that will just as bad for you as other saturated oils. Not even ‘Extra Virgin Refined Coconut Oil’ in the mistaken belief that such a label must indicate that the oil is extra good. It does not – it simply indicates that the supplier is a charlatan deliberately trying to mislead you into paying a premium price for a useless product. Coconut oil may promote a healthy thyroid and digestive function, and all the medical tests indicate that it does. People that use it regularly swear by it and if you have a problem that virgin coconut oil might help, then one thing is sure: it will certainly do you no harm, and all indications are that it will do you a lot of good.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1610) The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
Date:
May 18, 2007 01:06 PM
The Awesome Foursome: Coenzyme Q10, L-Carnitine,
D-Ribose, Magnesium
The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.
Coenzyme Q10:
Energy Recycling through the Electron Transport Chain
Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.
Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.
In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.
What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.
Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.
L-Carnitine:
Transporting the Cellular Energy Fuel
Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.
D-Ribose:
Rebuilding the Cellular Energy Pool
As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.
When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.
Ribose is the only compound used by the body to refill this energy pool. Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency. Ribose is made naturally in the cells from glucose. In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis. So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.
Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy. Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days. But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose. Conditions like ischemic heart disease or congestive heart failure fall into this category. In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.
Magnesium:
Switching on the Energy Enzymes
Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism. Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work. Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.
Magnesium deficiency reduces the activity of important enzymes used in energy metabolism. Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function. Small changes in magnesium levels can have a substantial effect on heart and blood vessel function. While magnesium is found in most foods - particularly vegetables - deficiencies are increasing. Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.
Supporting the Links in The Energy Cycle Chain – the Synergy
Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.
The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.
The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.
Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.
These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.
The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.
L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1539) EpiCore Benefits
Date:
April 09, 2007 05:02 PM
EpiCor® is a unique and novel dietary supplement used for support of immune health, with a fascinating history of discovery. In 1943, a company in
Interestingly, when the company became self-insured, they became aware of unusually low rates of illness in employees that worked in the manufacturing plant for this animal product. This led to very low increases in their insurance premiums over the years compared to other companies, saving them quite a lot of money. Hence they began to investigate what might be the cause of the “healthfulness” of the employees at the fermentation plant. This investigation and subsequent research studies led to the formation of a new company called Embria Health Sciences, which now produces EpiCor® as a supplement for humans to support immune system health.1 Doctor’s Best® is proud to now offer the benefits of EpiCor® to its customers.
Beneficial Support of the Immune System and Activation of Natural Killer (NK) Cells in vitro*
A comparison study was performed on blood from 10 fermentation plant workers compared to that from 10 age and gender matched controls. The fermentation plant workers had several immune cell parameters that appeared superior to the control group. These included decreased levels of CD8 cells resulting in significantly increased CD4 to CD8 ratios, significantly improved cytotoxic natural killer (NK) cell activity even though total NK cells were decreased in number, higher killing efficiency of NK cells, significantly increased levels of secretory IgA, increased numbers of EpiCor™ specific antibodies, higher levels of red blood cell intracellular glutathione, and significantly lower levels of immune complexes. These results represent benefits on various cellular players of both the specific and innate parts of the immune system.1,3,4
NK cells are one of the first lines of defense used by the immune system. An in vitro study performed on human cells showed that NK cells were activated after incubation with EpiCor®, as evaluated by expression of the CD69 activation marker. The CD25 marker (IL-2 receptor) was also induced in the NK cells, although to a lesser degree.1,2 B cell activation was also noted through increased expression of CD80 and CD86 markers.2 Immediate increases in calcium levels were evident in peripheral blood mononuclear cells after exposure to EpiCor®, suggesting increased activation through calcium regulation.2
High Metabolite Immunogen*: Nutrient Make-up
Production of EpiCor® utilizes the common and harmless bakers or brewers yeast Saccharomyces cerevisiae in a patented process called MetaGen4™, a multi-stage fermentation and drying process. It differs from other yeast products in that it contains both the yeast itself as well as the metabolites or “nutrilites” formed by the fermentation process, which are present in the media.1 Together the media containing the metabolites and the yeast are dried to form EpiCor®. Analysis of EpiCor® reveals that it contains a mixture of natural polyphenols, phytosterols, beta-glucans, mannan oligosaccharides, fiber, trace amounts of B vitamins and minerals, as well as a host of other nutritional compounds.1,2
Beneficial Antioxidant Activity*
EpiCor® was tested for antioxidant activity in an in vitro assay called the Oxygen Radical Absorbance Capacity assay (ORAC). In this assay, EpiCor® was shown to have a total ORAC antioxidant level of 610 micromol TE (tocopherol (vitamin E) equivalents) units (ORAC units) per gram dry weight, which soared above other high antioxidant level foods such as cranberries (93 ORAC units per gram dry weight) and blueberries (62 ORAC units per gram dry weight).1,3,5
In another study, freshly isolated human neutrophils were treated with EpiCor® followed by the free radical generator hydrogen peroxide. Cells were treated with a dye that fluoresces when attacked by free radicals. Those cells treated with EpiCor® showed decreased fluorescence intensity compared to control cells not treated with EpiCor®, verifying antioxidant activity in vitro.2
Safety
Numerous safety tests have been conducted on EpiCor®, revealing an extremely safe profile. Animal studies performed by a leading toxicology laboratory showed no indication of any toxic effects of EpiCor®. An acute oral toxicity study on 20 rats showed that the product was safe when given to rats at a single oral dose of 2000 milligrams per kilogram of body weight (equivalent to a human ingesting 280 capsules at once). After 2 weeks the rats showed no clinical symptoms, no deaths, no abnormalities in body weight, and no gross pathological changes. The same safety results were found in a subchronic toxicity study where rats were given up to 1500 milligrams daily for 90 days (equivalent to a human ingesting up to 210 capsules daily for 1.5 years). Again, absolutely no signs or symptoms of toxicity were noted in these animals.1,3
In addition, a standard bacterial reverse mutagenicity test (AMES test) as well as a mammalian cell mutation assay using mouse lymphoma cells revealed no evidence of any increase in mutation rates after exposure to EpiCor®. EpiCor® also showed no evidence of mitogenicity (inducing increased cell division) in a human lymphocyte proliferation assay. This suggests that EpiCor® does not cause over-reactivity of cells1,3.
The effect of EpiCor® on specific liver enzymes CYP1A2 and CYP3A4 (enzymes involved in metabolizing certain drugs and other compounds) was assessed. Immortalized hepatocytes (liver cells) were treated with various concentrations of EpiCor® and compared to both positive and negative controls. EpiCor® did not increase the expression or activity of the liver enzymes, suggesting that it may not affect the metabolism of other substances or medications metabolized by these enzymes if they are taken simultaneously. It also did not appear to be toxic to the cells as measured by lactate dehydrogenase assays and microscopic analysis.1
Lastly, EpiCor® was tested for safety in humans in an open label study on 15 adult men and women given a single 500 milligram dose for 30 days. On various days throughout the study vital signs were monitored, and blood and urine samples were analyzed. No clinically relevant abnormal effects on the participants were found1.
EpiCor® also currently has received self-affirmed Generally Regarded as Safe (GRAS) status by an expert panel that included eminent toxicologists1.
EpiCor® is a novel compound with an incredibly unique composition that has been shown to enhance immune system function.*
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Scientific References
1. Embria Health Sciences
2. Hart et al. A new Saccharomyces cerevisiae based product has anti-inflammatory effects while specifically activating human NK and B lymphocyte subsets. Unpublished study, personal communication.
3. Schauss AG, Jensen G, Vojdani A, Financsek I. After decades of ingestion by farm animals, the discovery of a yeast fermentate with unexpected significant immune modulatory activity when consumed by humans. [abstract] Journal of the
4. Schauss AG, Vodjani A. Discovery of an edible fermentation product with unusual immune enhancing properties in humans. [abstract] FASEB J, 2006; 20(4):A143.
5. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1508) l-Arginine/l-Citrulline Complex - Supports Peak Performance
Date:
March 06, 2007 02:24 PM
l-Arginine and l-Citrulline are two amino acids bundled into a single powerful supplement. Both are key intermediates in the Krebs urea cycle, where they participate in the detoxification of ammonia via the production of urea. In addition, any arginine not converted to urea enters general circulation where it is distributed to various tissues and metabolized for other uses such as protein synthesis. l-Arginine is probably best known for its role in cardiovascular health and the formation of nitric oxide (NO). The formation of NO mediates smooth muscle relaxation in the blood vessel wall, and thus reduces the workload of the heart. Many nerve cells also use NO as a signaling molecule. Erectile function, for example, is mediated by the release of NO from the autonomic nerves in the penis. Also, l-Arginine is an important factor in muscle metabolism promoting energy during exercise and increased recovery after a workout. 1 tablet contains: l-Arginine (as l-Arginine HCI) 750 mg l-Citrulline 250 mg Suggested Use: 1 tablet four times daily.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1478) Fruit and Vegetable Lightning drink mixes from Natures Plus
Date:
February 06, 2007 02:41 PM
Enjoy the Rainbow – the Color Wheel of Fruits and Vegetables
We’ve all heard the statistics, and have probably seen the signs in the produce section of our favorite grocery store: eating 5 servings of fruits and veggies a day is important,
Chances are also pretty good that we’ve also seen the newest food pyramid, encouraging Americans to “eat a rainbow of frits and vegetables.” That is, choose from the rich variety of colors for the best all-around health benefits.
In this Ask the Doctor, we’re going to look at the unique health components of different colored fruits and vegetables, and why they’re so important. Plus, we’ll learn about supplemental options, like fruit and vegetable drink mixes, for those days when our diets just aren’t that great.
Q. What’s the big deal about fruits and vegetables?
A. Well, for the main reason that they are whole foods – created by nature (or at least generations of farming) and are rich in a variety of nutrients. Processed foods can’t match the health benefits of strawberries or broccoli – items that have fiber, vitamins, and enzymes built right in.
Q. What does “eating a rainbow” of fruits and vegetables really mean?
A. This is simply an easy way of remembering to get as much color variety in your diet as possible to maximize your intake of a broad range of nutrients. The colors of fruits and vegetables are often a tangible clue to the unique vitamins and other healthy substances they contain. Getting a variety of colors, therefore, means getting a variety of the essential nutrients your body needs to stay healthy and strong.
Enjoying the Rainbow: Fruit and Vegetable Benefits:
Q. Can you tell me a little more about the healthy components of fruits and vegetables?
Let’s take a look at some of the most well-studied and important nutrients:
Quercetin is found in apples, onions and citrus fruits (also is hawthorn and other berries and apple-related fruits usually used in traditional herbal remedies and modern supplements). It prevents LSL cholesterol oxidation and helps the body cope with allergens and other lung and breathing problems.
Clinical studies show that quercetin’s main points of absorption in the body appear to be in the small intestine – about 50%. The rest – at least 47% is metabolized by the colonic micro flora – the beneficial bacteria such as Lactobacillus acidophilus and Bifidobacterium longum. You may consider adding these beneficial bacteria (found in yogurt) either through the diet or a supplemental form.
Ellagic Acid is a component of ellagitannins – dietary polyphenols with antioxidant (and possibly anticancer) properties. Polyphenols are the basic building blocks of many plant-based antioxidants. More complex phenolic compounds, such as flavonoids are created from these molecules.
Ellagic acid is found in many fruits and foods, namely raspberries, strawberries, pomegranates, and walnuts. Clinical studies suggest that ellagitannins and ellagic acid act as antioxidants and anticarcinogens in the gastrointestinal tract.
Ellagitannins are durable antioxidants, and happily, they do not appear to be diminished by processing, like freezing. This means the benefits are still strong, even in frozen packs of raspberries or strawberries, or some of the better multi-ingredient supplement drink mixes.
In scientific studies, ellagic acid also showed an anti-proliferative effect on cancer cells, decreasing their ATP (adenosine triphosphate) production. ATP is the molecule that provides the primary energy source for the cells in our bodies. In a sense, ellagic acid seems to deprive cancer cells of their fuel.
Beta-Carotene: Probably the best-known of the carotenoids, beta-carotene is converted by the body into vitamin A. Many vegetables, especially orange and yellow varieties, are rich in this nutrient. Think summer squash, yams and of course, carrots.
Beta-carotene has long been associated with better eyesight, but it has other benefits, too. In a scientific study, beta-carotene decreased cholesterol levels in the liver by 44% and reduces liver triglycerides by 40%.
Lycopene is a carotenoid mostly found in tomatoes, but also in smaller amounts in watermelon and other fruits. Clinical studies have shown that lycopene consumption may decrease the risk of prostate cancer. In fact, high intakes of lycopene are associated with a 30% to 40% reduced risk. And, as good as beta-carotene is, its cousin, lycopene, seems to be an even stronger nutrient, protecting not just against prostate cancer, but heart disease as well.
Lutein is found in many fruits and vegetables, including blueberries and members of the squash family. Lutein is important for healthy eyes, and in fact it is found in high concentrations naturally in the macular region of the retina – where we see fine detail. It is one of the only carotenoids, along with its close sibling zeaxanthin, that is found in the macula and lens of the eye.
Lutein also supports your heart, too. In a scientific study, lutein reduced atherosclerotic lesion size by 43%. In other words, high intakes of lutein may actually help prevent coronary artery disease!
Interestingly, as is the case with lycopene, cooking or processing foods with lutein may actually make it more easily absorbed.
In clinical studies, men with high intakes of lutein (and its close cousin, zeaxanthin, found in broccoli and spinach) had a 19% lower risk of cataract, and women had a 22% decreased risk, compared to those whose lutein intakes were much lower.
Vitamin C: One of the best-known nutrients out there, vitamin C keeps our immune system strong; speeds wound healing, and promote strong muscles and joints. A free-radical fighter, vitamin C prevents oxidative damage to tissues, builds strength in collagen and connective tissue, and even reduces joint pain.
Sources of vitamin C are scattered throughout the spectrum of fruits and vegetables.
Potassium: Most Americans are deficient in potassium. For the most part, it’s hard to get too much of this valuable mineral. Potassium does great things for our hearts. Higher intakes of dietary potassium from fruits and vegetables have been found in clinical research to lower blood pressure in only 4 weeks.
Many researchers believe that the typical American diet has led to a state of chronic, low-grade acidosis – too much acid in the body. Potassium helps change pH balance to a more alkaline environment in the body and increases bone density.
This was proven in the long-running Framingham Heart Study which showed that dietary potassium, (along with magnesium and fruit and vegetable intake) provided greater bone density in older individuals.
Fiber is another food component many just don’t get enough of – especially if they’re eating a “typical American diet.” Fruits, vegetables and whole grains are excellent sources of fiber. However, fiber from a good fruits and vegetable drink mix should be derived from inulin and chicory root. This soluble fiber source not only adds to the overall amount of fiber you need (25 to 38 grams a day), but also provides a nice “nesting ground” for the beneficial bacteria that populate the intestines. And, even though some fiber has a bad rap for inhibiting mineral absorption, inulin and chicory root are “bone building” fibers – they actually help the body absorb calcium.
Flavonoids are an overarching term that encompasses flavonols, anthocyanidins, and flavones, isoflavones, proanthocyanidins, Quercetin and more. They are almost everywhere: in fruits, vegetables, grains, herbs, nuts and seeds – even in the coffee, wine and tea we drink. Flavonoids are responsible for the colors in the skins of fruits and the leaves of trees and other plants.
Flavonoids have many health benefits. They can help stop the growth of tumor cells and are potent antioxidants. Additionally, flavonoids have also been studied for their ability to reduce inflammation.
Anthocyanins: High on the list of important “visible” nutrients are anthocyanins. They color fruits and vegetables blue and red.
Anthocyanins are members of this extended family of nutmeats, the flavonoids. Typically found in high amounts in berries, anthocyanins are readily absorbed in the stomach and small intestine.
As antioxidants, anthocyanins dive deep into cell membranes, protecting them from damage. IT may be one reason why the anthocyanins from blueberries are considered such an important component in battling neuronal decline, like Alzheimer’s. Blackberries, raspberries, and strawberries are also excellent sources of this flavonoids group.
SDG lignans, (short for secoisolariciresinol diglucoside) are polyphenolic components of flaxseed, pumpkin and other herbal sources. Much of the recent research surrounding lignans has focused on flaxseed. In scientific and clinical studies, lignans from flaxseed support hormonal balance and may have cancer-preventing abilities. In fact, in one study, flaxseed lignans reduced metastatic lung tumor by 82% compared to controls.
The lignans in pumpkin seed, also considered a major source, target 5-alpha reductase activity.
This enzyme catalyzes the conversion of testosterone into the more potent dihydrotestosterone (DHT). DHT, like testosterone, is a steroid hormone or androgen. Androgens are responsible for the development and maintenance of masculine sex characteristics in both men and women. Excess levels of DHT can cause serious problems with prostate or bladder health. That’s why modulation of the 5-alpha reductase enzyme is so important – it helps maintain healthy testosterone and DHT levels. By balancing the levels of these key hormones, pumpkin seed lignans provide protection for prostate and bladder cells.
In addition, pumpkin seed has been shown to modulate the enzyme aromatase. Aromatase is present in the estrogen-producing cells of the adrenal glands, ovaries, testicles, adipose tissue, and brain. Aromatase converts testosterone, an androgen, into estradiol, and estrogen.
Inhibition of the aromatase conversion can help maintain a balance of healthy testosterone levels in women, which has been shown to strengthen pelvic muscles and reduce incidence of incontinence.
In fact, a clinical study, involving a pumpkin extract in conjunction with soy, resulted in significant support for bladder health. After two weeks of supplementation, 23 of the 39 postmenopausal women enrolled in the study showed great improvement in urinary frequency and sleep. By the end of the six week study, 74.4 percent of participants found pumpkin extract safely and significantly improved “nocturnia,” that is, the need to urinate frequently at night. For individuals with 2 to 4 episodes of nocturnia prior to the stud, and 81.8% improvement was seen – also showing great improvement in sleep quality. After all, if you don’t have to wake up every couple of hours to go to the bathroom you’re bound to get better sleep.
Beta glucan: Mushrooms are intense immune-boosting powerhouses due to their beta-glucan content. Three well-studied power-house mushrooms that contribute beta glucan to the diet include maitake, reishi and shiitake.
The most significant constituents of mushrooms are long chain polysaccharides (molecules formed from many sugar units) known as beta-glucan. These huge molecules act as immunoregualtors in the human body, helping to stabilize and balance the immune system.
This includes specific support of white blood cells, or lymphocytes, the primary cells of the immune system. Lymphocytes fall broadly into three categories: T cells, B cells, and natural killer (NK) cells.
In one clinical study, 165 patients with various types of advanced cancer were given maitake mushroom compounds alone or with chemotherapy. Cancer regression or significant symptom improvement was observed in 58% of liver cancer patients, and 62% of lung cancer patients. Plus, when maitake was taken in addition to chemotherapy, the immune cell activities were enhanced 1.2 to 1.4 times, compared with chemotherapy alone.
In another clinical study, researchers determined that Reishi increased the number of cancer killing white blood cells and made them more deadly to cancer cells.
And, in a scientific study of human breast cancer and myeloma cancer and myeloma cancer cell lines, shiitake compounds provided a 51% antiproliferative effect on the cells – inducing “apoptosis’ – the programmed cell death that should occur naturally.
While beta-glucan are distributed throughout the mushroom body, the beta-glucan concentrations are significantly higher in the mycelium – the interwoven fibers or filaments that make up the “feeding structure” of the mushroom.
Bioflavonoids are commonly found in bright yellow citrus fruits, including lemons, limes and oranges. They are responsible for the bright pigment found in the skin of the fruit, and are considered a “companion” to vitamin C, seeming to extend the value of the nutrient within the body.
Hesperidin is just one of the valuable bioflavonoids found in citrus. Hesperidin appears to lower cholesterol levels, as well as support joint collagen in examples of rheumatoid arthritis.
Epigallocatechin gallate (EGCG):
Polyphenols, most notably EGCG, or epigallocatechin gallate, are well-studied and powerful components of tea. EGCG has been shown to reduce colon and breast cancer risk. Green tea also boosts the immune system and encourages T-cell formation – part of the front-line defense of our bodies against sickness and disease.
Q. I’ve been seeing articles about fruits, vegetables and supplements touting “high ORAC value.” What does this mean?
ORAC is an acronym for Oxygen Radical Absorption Capacity, and is simply a measurement of antioxidant activity of nutrients. Oxygen radicals, or free radicals, are unstable molecules. They grab electrons from other cells to use for themselves, and in the process can damage them. It is believed that free radical activity plays a role in the development of many diseases such as heart disease and cancer, and also plays a role in aging.
Antioxidants help prevent this damage by “loaning out” extra electrons to stabilize free radicals/ Consider any fruit or vegetable with a high ORAC rating as having a lot of “antioxidant power.”
I know I should eat more fruits and vegetables, but it just seems so hard to get five servings a day.
The number one excuse I hear for not buying frits and veggies is that “fruits and vegetables are too expensive.” But are they really? Certainly, fresh foods that aren’t in season and have to be shipped a distance can be a bit pricey. If anyone added up how much spend on fast food, or prepackaged or processed snacks, it would probably be shocking.
Luckily, there are many ways to get your “Daily 5”. For instance, frozen fruits and veggies retain much of their nutrient profile. They can be an excellent alternative when certain foods are out of season. So too, are fruit and vegetable drink mixes – excellent supplemental sources of some of the nutrients our bodies need most.
More recently, the American
Of course, for people not accustomed to the fiber in fruits and veggies, there is some reason to think it’ll increase gas. When cell walls break down, and fiber passes through the system, it can create flatulence. Folks who eat fruits and vegetables every day generally don’t have this problem. Their systems are already accustomed to it.
For those just starting out on a better diet, however, start slowly – it helps your body adapt. Cooking vegetables can help, too, because it begins breaking down the cell walls early on.
One thing is certain, however. The “Typical American Diet” and good health are mutually exclusive. The increase in type 2 diabetes, heart disease, high cholesterol, and hypertension all point to the abuse our bodies suffer by eating diets high in fatty meats, processed sugars, and refined grains.
Q. Can I just drink fruit and vegetables drinks in place of 5 servings of fruits and vegetables?
Green drinks and fruit and vegetable drink mixes aren’t meant to replace whole foods, but they can be an excellent substitute when you’re rushed or traveling or just trying to fill everyday nutritional gaps. Their whole food ingredients absorb very easily and gently in the gut, and many of these drink mixes contain healthy doses of fiber, too.
Green drink mixes and food-based drink mixes combine many colorful fruits and vegetables and sometimes grasses in a healthy, mixable supplement assortment. While there have been many advancements in the field of green drinks, there are only a few that take the primary reason we eat into consideration: taste!
Happily, there are some companies out there with great-tasting drink mixes that also formulate based on the color concept, ensuring you get the broadest assortment of nutrients from a full range of fruit and vegetable colors to promote optimal health.
High-quality fruit and vegetable drink mixes offer the best from nature’s color wheel in a convenient and great-tasting supplement. So, the next tie you feel like taking a coffee break – try a fruit and veggie break instead. Your body and spirit will thank you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1451) HDL Booster - Boost your good cholesterol
Date:
March 16, 2006 12:51 PM
HDL BOOSTER
(Product No. 02922)
DESCRIPTION:
HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*
HDL Booster:
· Formulated by Dr. Dennis Goodman, Chief of Cardiology at
· Clinically studied to increase good cholesterol levels up to 23%*1
· All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association
· Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2
STRUCTURE/FUNCTION:
HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*
FORMULA:
Two tablets (one serving) contain:
Vitamin C (ascorbic acid) 148 mg
Vitamin E (as natural mixed tocopherols) 35 IU
Niacin (as niacinamide) 21 mg
Vitamin B6 (as pyridoxine HCl) 3 mg
Folic Acid 301 mcg
Vitamin B12 (as cyanocobalamin) 20 mcg
Magnesium (from magnesium amino acid chelate) 10 mg
Selenium (as L-selenomethionine) 49 mcg
Proprietary Blend 388 mg
hawthorn (Crategus oxyacantha) berry extract,
taurine, garlic (Allium sativum) bulb, grape seed (Vitis
vinifera) extract, grape skin (Vitis vinifera) extract,
N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine
max) isoflavones, tocotrienols
L-Arginine (as L-arginine HCl) 153 mg
L-Carnitine (as L-carnitine L-tartrate) 51 mg
Coenzyme Q10 (CoQ10)(ubiquinone 10) 25 mg
Policosanol 7 mg
Other ingredients: See label for most current information.
Contains no: sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives. This product contains natural ingredients; color variations are normal.
INTRODUCTION:
Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5
Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4
Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4
Types of Cholesterol
Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5
LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6
Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7
The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7
HOW IT WORKS:
HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9
Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at
The following chart summarizes the benefits of each of the ingredients in HDL Booster:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1238) California Proposition 65 (Prop 65) and Progesterone Cream Warnings
Date:
February 17, 2006 06:29 PM
Scientific Safety Information on Progesterone California Proposition 65 (Prop 65) and Progesterone Cream Warnings Amy Kosowski, M.S., LDN Prop 65: What is it? Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986 , was enacted as a ballot initiative in the state of California in November of 1986. The Proposition was intended by its authors to protect California citizens and the State's drinking water sources from chemicals known to cause cancer, birth defects or other reproductive harm, and to inform citizens about exposures to such chemicals 1. Proposition 65 requires the Governor to publish, at least annually, a list of chemicals “known to the state to cause cancer or reproductive toxicity .” Progesterone, as well as other human hormones, appear on this list 1. Set forth below is the information that formed the bases for the addition of progesterone to the Prop 65 list by the California Office of Environmental Health Hazard Assessment (“OEHHA”). Prop 65 and Progesterone - Perspective
In August of 2004, OEHHA published a document stating the rationale for the addition of Progesterone to the Prop 65 list 2. This document is a review of human, animal, and in vitro studies that used progesterone, synthetic progestins, and other progestagens (progesterone-like compounds). Experimental data from the use of all of these compounds were mixed together, along with data from studies using other steroid hormone derivatives (mainly synthetic estrogens) and many different methods of administration. Although this review covered the existing scientific literature on progesterone and its many derivative compounds, there are many problems with the type of data analysis that was employed. First, progesterone is endogenous to humans and necessary for bone and reproductive health while progestins and other synthetic progestagens are not. Progestins and progestagens are similar in molecular structure to progesterone, but when they bind to progesterone receptors, their effects are usually much stronger and more likely to cause abnormal physiologic responses 3, 4. Furthermore, the majority of the studies concerning the health effects of these progesterone derivatives involved combinations with synthetic estrogens 2-4. There were very few studies mentioned in the 2004 document that used exclusively bio-identical progesterone (the kind found normally produced by humans as well as that used in progesterone creams), and those studies that did were at supra-physiologic doses (very high). The doses of progesterone ranged from 10-1000 times the dose usually recommended by manufacturers of progesterone creams 2, although in a few cases, the doses were closer to the recommended dosages. The route of administration of progesterone is also at issue. All of the studies cited in the OEHHA document used either oral, injected, or suppository forms of hormones; none was conducted using transdermal creams. This is an important consideration because hormones absorbed through the skin are metabolized differently than hormones that are administered via other routes 5, 6. Putting it Together While the OEHHA Prop 65 reference document on progesterone 2 is a broad survey of the published scientific literature examining the potential effects of the pharmaceutical use of progesterone and its synthetic derivatives, it is not clear at all that these effects would be seen with the use of low-dose progesterone creams. The OEHHA Prop 65 progesterone document evaluates a broad range of information regarding progesterone and synthetic materials that are not natural progesterone. The conclusion reached was not challenged, and it is on that basis that progesterone creams now carry the Prop 65 warning.
1 California OEHHA Web Site: //www.oehha.ca.gov/prop65/p65faq.html . 2 Reproductive and Cancer Hazard Assessment Section, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency (2004) Evidence on the developmental and Reproductive Toxicity of Progesterone. 3 Campagnoli C, Abba C, Ambroggio S, Peris C (2005) Pregnancy, progesterone and progestin in relation to breast cancer risk. J Steroid Biochem Mol Biol 97(5):441-450. 4 Campagnoli C , Clavel-Chapelon F , Kaaks R , Peris C , Berrino F (2005) Progestins and progesterone in hormone replacement therapy and the risk of breast cancer. Steroid Biochem Mol Biol 2005 96(2):95-108. 5 de Lignieres B, Dennerstein L, Backstrom T (1995) Influence of route of administration on progesterone metabolism. Maturitas 21:251-257. 6 Gompel A, et al. (2000) Progestins were also proapoptotic in normal as well as in hormone-dependent breast cancer cells. Steroids 65(10-11):593-598. 7 Bu SZ ( 1997) Progesterone induces apoptosis and up-regulation of p53 expression in human ovarian carcinoma cell lines. Cancer 79(10):1944-50.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1224) Benefits of L-Carnitine
Date:
February 12, 2006 03:24 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1218) Potent Antioxidant Protection *
Date:
February 11, 2006 09:28 AM
Goji berry possesses a unique combination of flavonoids, vitamins, minerals and polysaccharides that are thought to be responsible for the antioxidant and anti-aging properties attributed to Goji. Studies have been conducted which characterize some of these antioxidant nutrients and show possible beneficial effects of the berry and its extracts on various systems and organs. In a study published in 2004, scientists undertook an experiment to assess whether Goji berries contained compounds that would be known to exert potential beneficial effects on skin complexion and anti-aging properties. After analyzing the berry, leaf and roots of the Goji plant, they found that the Goji berry contained a unique analog of vitamin C known as 2-O-(beta-D-glucopyranosyl) ascorbic acid. They determined that this compound was unique to the berry and not found in the other parts of the plant. Furthermore, the vitamin C compound was present in levels equivalent to those found in citrus fruits such as lemons. However, the question remained as to whether this vitamin C analog served as a precursor to vitamin C when ingested in the body. A further experiment in rats was performed to determine the intestinal absorption and tissue uptake of this vitamin C analog. The results showed that some of the compound was indeed metabolized into vitamin C in the blood, while the rest was absorbed intact. These studies suggested that the compound was easily transported from the blood into cells and tissues, where it is activated to active vitamin C. Therefore, the vitamin C from Goji berries seems to be highly absorbable and targeted for delivery to the cells that utilize it.1 Zeaxanthin is a carotenoid that is widely distributed in fruits and vegetables and, along with lutein, is present in significant amounts in the macula of the human eye. Studies suggest that the presence of zeaxanthin is highly desirable for healthy visual function. Goji berries are used in traditional Chinese herbalism to support eye health and are also known to contain a high level of zeaxanthin dipalmitate. Researchers compared the bioavailability of this naturally esterified zeaxanthin to that of an unesterified form in 12 individuals who underwent a 23-day study in which they received one form or the other, and then switched. Administration was done on day one followed by a three-week washout period. The individuals were then crossed over to get the other form on day 23 in a single administration. Analysis revealed that the esterified zeaxanthin from Goji berry caused a higher increase in plasma levels than the non-esterified form, indicating higher bioavailability.2 A second study confirmed these findings. In this study, fourteen individuals consumed 15 grams of whole Goji berries daily for 28 days. These individuals were compared to thirteen age and sex-matched controls who did not consume the berries. Fasting blood samples were taken for all individuals before and after the 28-day period. Results indicated that zeaxanthin plasma levels increased 2.5-fold in the group who consumed the berries daily, suggesting the high bioavailability of zeaxanthin from the berries.3 Goji berry was also studied on various measures of antioxidant activity. Researchers subjected three Chinese herbs, one of which was Goji berry, to various assays of reactive oxygen scavenging potential. The results indicated that all of the herbs had significant free radical scavenging properties; however, Goji berries showed the most potent scavenging effect in the assays. Goji berry was especially strong at inhibiting the formation of superoxide anion and scavenging free radicals. The researchers concluded that among these herbs, Goji could be considered the best antioxidant to promote healthy aging.4 An interesting study was performed in human skin cultures to determine the mechanism of the potentially protective effect of Goji berry extracts. Researchers found that bathing human skin cultures with an extract from Goji berry impacted the function of several enzymes that promote skin aging. This provides evidence of an anti-aging and antioxidant effect of Goji berry extract in these human skin cultures. Researchers also noted that when these skin cultures were subjected to suboptimal growth conditions (lack of adequate nutrients), supplementing the medium with this Goji berry extract allowed the skin to maintain normal metabolic functions.5 Goji berry extract contains numerous compounds that confer potent antioxidant protection to various tissues.*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1212) Pomeratrol™ Fact Sheet
Date:
December 19, 2005 09:09 AM
Pomeratrol™ Fact SheetNeil E. Levin, CCN, DANLA 9/28/04USER: Those needing antioxidant protection; People with a family history of cell growth abnormalities; Anyone concerned with aging KEY INGREDIENT(S): Pomegranate fruit standardized extract 200 mg. (Punica granatum) containing 80% total polyphenols, including 40% Ellagic acid, Resveratrol (100% trans-resveratrol) 20 mg. from a blend of Japanese knotweed root extract (Polygonum cuspidatum) and grape skin extract (Vitis vinifera) POTENTIAL BENEFITS: Ellagic acid is a polyphenol compound found in raspberries, strawberries, pomegranates, and other fruit. It has been shown to normalize cell death of abnormal cells, a process called apoptosis. This enhances the body’s cell growth control system by providing an important plant substance. It may bind to DNA to prevent damage to this all-important genetic material. This is a key step in preventing cell damage that leads to signs of aging. The American Cancer Society says that research in animal and laboratory models has found that ellagic acid inhibits the abnormal growth of certain cells. Research at Ohio State University indicates that berries typically contain a few milligrams per ounce of ellagic acid, the actual level varying quite a bit from variables such as species, variety and growing conditions. Resveratrol is an antioxidant compound that is a phytoestrogen, or plant estrogen, which is protective of hormone-mediated cells in the body. Resveratrol is a potent antioxidant if stabilized. If not stable, it may quickly metabolize out of the body. This compound is believed responsible for some of the beneficial effects of moderate red wine drinking on the cardiovascular system. Resveratrol is also considered to be beneficial to smokers’ lung tissue if it is stabilized to last long enough in the system to be transported there. Resveratrol is also an inhibitor of the COX-2 inflammatory enzyme and encourages cell death (apoptosis) of abnormally growing cells. In insect experiments resveratrol even repaired DNA, leading to a longer life for healthy cells even as it helped get rid of unhealthy cells. Again, this ability to protect cells and help the body rid itself of abnormal cells is a key factor in preventing signs of aging. One liter of red wine contains between 1.5 and 3 mg. of resveratrol. OTHER IMPORTANT ISSUES: Resveratrol is a difficult substance to stabilize. Because of the difference between resveratrol produced in the oxygen-poor environment in red wine and the form of resveratrol in unstabilized supplements, it has long been thought that resveratrol supplements were not very effective in comparison with wine. Knowing the importance of how a resveratrol supplement is metabolized, Now’s scientific staff has recently developed a special technique of stabilizing this compound in order to have an antioxidant effect closer to drinking a good glass of wine. While both trans and cis forms of resveratrol are naturally occurring, most of the recorded health benefits are attributed to the trans form. Now’s Pomeratrol provides trans-resveratrol. DOSE: One capsule per day. Resveratrol has been used safely in studies at doses equivalent to 500 mg./day. COMPLEMENTARY PRODUCTS: Other antioxidants and plant compounds: Vitamin C, pycnogenol, grape seed extract, and alpha lipoic acid.
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. There are some indications that resveratrol is a mild anticoagulant ("blood thinner"), and it also may help keep blood vessels to remain open and flexible. Caution should be used by those on blood-thinning drugs. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1039) SAMe (S-Adenosylmethionine)
Date:
December 17, 2005 09:42 AM
Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body. There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable. Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel. SAMe (S-Adenosylmethionine) SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.* SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance. As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants. Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health. SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification. SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were granted to allow the production of SAMe in a stabilized form. SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability. This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1019) Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)
Date:
August 02, 2005 03:52 PM
Benefits Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine.4 Thiamine and its Co-enzyme, TPP Thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically-catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name "thiamine diphosphate." In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as "active acetate." Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb’s cycle (citric acid cycle). The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called "oxidative decarboxylation," and for this reason, TPP was originally referred to as "cocarboxylase." TPP is thus vital to the cell’s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below. Benfotiamine and Glucose Metabolism Benfotiamine normalizes cellular processes fueled by glucose metabolites. As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell’s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the Krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.5 In the presence of elevated glucose levels, the electron transport chain, the final ATP-generating system in the mitochondrion, produces larger than normal amounts of the oxygen free radical "superoxide." This excess superoxide inhibits glyceraldehyde phosphate dehydrogenase (GAPDH), as key enzyme in the conversion of glucose to pyruvic acid, resulting in an excess of intermediate metabolites known as "triosephosphates." Increase triosephophate levels trigger several cellular mechanisms that result in potential damage to vascular tissue. Cells particularly vulnerable to this biochemical dysfunction are found in the retina, kidneys and nerves. Benfotiamine has been shown to block three of these mechanisms: the hexosamine pathway, the diaglycerol-protein kinease C pathway and the formation of Advanced Glycation End-poducts. As discussed below, benfotiamine does this by activating transketolase, a key thiamin-dependent enzyme.6 Benfotiamine stimulates tranketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.* Transketolase diverts the excess fructose-6-phosphate and glyceraldehydes-3-phosphate, (formed by the inhibition of GAPDH, as mentioned above), into production of pentose-5-phosphates and erythrose-4-phosphate and away from the damaging pathways. Benfotiamine activates transketolase activity in bovine aortic endothelial cells incubated in glucose.6 To test benfotiamine’s ability to counteract these metabolic abnormalities caused by elevated blood glucose, studies have been done in diabetic rats. Benfotiamine increases transketolase activity in the retinas of diabetic rats, while concomitantly decreasing hexosamine pathway activity, protein kinase C activity and AGE formation.6 Benfotiamine and Protein glycation Benfotiamine controls formation of Advanced Glycation End-products (AGEs). AGEs have an affinity for proteins such as collagen, the major structural protein in connective tissue. AGEs are formed through abnormal linkages between proteins and glucose. This occurs via a non-enzymatic glycosylation reaction similar to the "browning reaction" that takes place in stored food.7 At high glucose concentrations, glucose attaches to lysine, forming a Schiff base, which in turn forms "early glycosylation products." Once blood glucose levels return to normal levels, the amount of these early glycosylation products decreases, and they are not particularly harmful to most tissue proteins. On long-lived proteins such as collagen, however, early glycosylation products are chemically rearranged into the damaging Advanced Glycation End-products. AGE formation on the collagen in coronary arteries causes increased vascular permeability. This vessel "leakiness" allows for abnormal cross-linking between plasma proteins and other proteins in the vessel wall, comprising vascular function and potentially occluding the vessel lumen. A number of other potentially harmful events may also occur, including production of cytokines that further increase vascular permeability. Endothelin-1, a strong vasoconstrictor, is over produced, increasing the possibility of thrombosis and generation of oxygen free radicals is stimulated.8 It is vitally important to support normal glucose metabolic pathways so that formation of AGEs is minimized. Benfotiamine, in the test tube (in vitro) prevents AGE formation in endothelial cells cultured in high glucose by decreasing the glucose metabolites that produce AGEs.9 Endothelial cells make up the membranes that line the inner walls of organs and blood vessels. In a rat study comparing the effects of Benfotiamine with water-soluble thiamin, Benfotiamine inhibited AGE formation in diabetic rats while completely preventing formation of "glycooxidation products," which are toxic by products of chronic elevated blood glucose. AGE levels were not significantly altered by thiamin.10 Benfotiamine also normalized nerve function in the animals. After three months of administration, "nerve conduction velocity (NCV)," a measure of nerve function, was increased by both benfotiamine and thiamin; at six months, NCV was normalized by benfotiamine, whereas thiamin produced no further increases in this parameter. Dysfunctional glucose metabolic pathways leading to AGE formation occurs in endothelial cells of the kidneys. In a recent animal study, benfotiamine was administered to rats with elevated glucose levels. Benfotiamine increased transketolase activity in the kidney filtration system of these rats, while at the same time shifting triosephophates into the pentose pathway and preventing protein leakage.11 Safety Benfotiamine has an excellent tolerability profile and can be taken for long periods without adverse effects.3,12 The statements in this fact sheet have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1. Bitsch R, Wolf M, Möller J. Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative. Ann Nutr Metab 1991;35(2):292-6. 2. Schreeb KH, Freudenthaler S, Vormfelde SV, et al. Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate. Eur J Clin Pharmacol 1997; 52(4):319-20. 3. Loew D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin Pharmacol Ther 1996;34(2):47-50. 4. Frank T, Bitsch R, Maiwald J, Stein G. High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. Eur J Clin Pharmacol. 2000;56(3):251-7. 5. Pike RL, Brown ML. Nutrition, An Integrated Approach, 3rd Ed. New York:MacMillan; 1986:467. 6. Hammes H-P, Du X, Edlestein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic neuropathy. Nat Med 2003;9(3):294-99. 7. Monnier VM, Kohn RR, Cerami A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci 1984;81(2):583-7. 8. Brownlee M. The pathological implications of protein glycation. Clin Invest Med 1995;18(4):275-81. 9. Pomero F, Molinar Min A, La Selva M, et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol 2001;38(3):135-8. 10. Stracke H, Hammes HP, Werkman D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes 2001;109(6):300-6. 11. Babaei-Jadidi R, Karachalias N, Ahmed N, et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 2003;52(8):2110-20. 12. Bergfeld R, MatsumaraT, Du X, Brownlee M. Benfotiamin prevents the consequences of hyperglycemia induced mitochondrial overproduction of reactive oxygen specifies and experimental diabetic neuropathy (Abstract) Diabetologia 2001; 44(Suppl1):A39.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=721) WHY TOPICAL APPLICATION OF NATURAL PROGESTERONE?
Date:
July 25, 2005 10:00 PM
WHY TOPICAL APPLICATION OF NATURAL PROGESTERONE? Progesterone is a fat soluble compound which maintains its integrity much more readily when absorbed transdermally (through the skin) than when taken my mouth. When progesterone is ingested orally, it is subject to rapid breakdown (metabolism) in the liver, making it considerably less effective. Medical practitioners have used synthetic progesterone in a variety of forms ranging from capsules to injections to vaginal and rectal suppositories. Originally, orally administered progesterone or progestins were not efficiently absorbed through the intestinal wall and had to pass through liver tissue before entering the bloodstream. Consequently, much of the absorbed progestins were metabolized by the liver into inactive compounds. Up to 80 percent of the effectiveness of progesterone can be lost when taken orally.6 By contrast, progesterone is very nicely absorbed transdermally (through the skin) and much more of its biochemical activity is retained. I believe that natural progesterone cream derived from wild yam extract should be used by almost every mature adult . . . I believe that progesterone cream could do more to preserve health and well-being in elderly people than all the drugs in the world.7 Dr. Lee reiterates that “. . . natural progesterone is efficiently absorbed transdermally, a fact that enhances patient’s acceptance of its use and greatly reduces the cost of therapy.”8 Salivary hormonal lab tests are becoming more common and have further supported the effectiveness of natural progesterone absorption through the skin by monitoring levels.9 These tests have proven that progesterone levels rise when wild yam extracts are applied to the skin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=663) The Role of Naturally Occurring Progesterone in the Body
Date:
July 25, 2005 09:50 PM
The Role of Naturally Occurring Progesterone in the Body In light of the previous section, it is vital to keep in mind that when progesterone is produced and maintained, most of the negative side effects of estrogen are neutralized. Unfortunately, in far too many women, progesterone levels fail to do the job. Let’s discuss exactly what progesterone is responsible for. A woman’s ovaries produce two key hormones: estrogen and progesterone during her ovulatory years. The corpus luteum makes progesterone just before ovulation which rapidly escalates during the two week period following ovulation. The primary task of progesterone is to support implantation and sustain pregnancy. It does this by inhibiting uterine contraction and by suppressing the immune system’s response to the developing embryo as a foreign body.2 During the last two weeks of a woman’s menstrual cycle, progesterone is considered the dominant female hormone. During pregnancy, the placenta takes over the task of progesterone synthesis. Progesterone is also made in limited amounts in the adrenal glands of both men and women and in the testes of the male. PROGESTERONE SECRETION RATES The following breakdown gives general guidelines of amounts and time of progesterone secretion: Approximately twelve days following ovulation, if fertilization has not occurred, progesterone levels decline rapidly, which initiates the shedding of the uterine lining, also known as menstruation. In time, progesterone is transported through the bloodstream to the liver where it is metabolized and excreted as waste through the kidneys (urine) and the bile. Typically, pregnancy tests are reacting to increased levels of HCG or of progesterone in the urine, indicating that pregnancy has occurred. (Note: What is crucial to remember is that a woman’s cycle, regardless of her age, may not be characterized by the above scale. A number of factors may cause estrogen to remain dominant, even after progesterone is supposed to take over in the latter half of the cycle. Even young women who suffer from nutritional deficiencies, stress, etc. may experience an estrogen dominance, suggesting the need for natural progesterone supplementation.) THE THREE-FOLD ACTION OF PROGESTERONE 1. It ensures the implantation and development of a fertilized egg and subsequent embryo and fetus. 2. It acts as a precursor to other steroid hormones such as cortisone which is produced in the adrenal glands and contributes to the production of the sex hormones including testosterone. 3. It exerts a number of desirable physiological actions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=656) ARTIFICIAL SWEETENERS: CAUSE FOR WORRY
Date:
July 15, 2005 12:26 PM
ARTIFICIAL SWEETENERS: CAUSE FOR WORRY Among some of the most troubling food additives that we routinely ingest are artificial sweeteners, also referred to as non-nutritive sweeteners. Having received the FDA stamp of approval, they are liberally ingested with little thought to what their actual health risks may be. Andrew Weil, M.D., in his book Natural Health Natural Medicine, writes: More worrisome than preservatives are artificial sweeteners. Saccharin, a known carcinogen, should be avoided. Cyclamates, banned some years ago for suspected carcinogenicity, are not being reconsidered for use in food. They taste better than saccharin but cause diarrhea in some people. Avoid them too. Recently, aspartame (NutraSweet) has become enormously popular. The manufacturer portrays it as a gift from nature, but, although the two component amino acids occur in nature, aspartame itself does not. Like all artificial sweeteners, aspartame has a peculiar taste. Because I have seen a number of patients, mostly women, who report headaches from this substance, I don’t regard it as free from toxicity. Women also find that aspartame aggravates PMS (premenstrual syndrome). I think you are better off using moderate amounts of sugar than consuming any artificial sweeteners on a regular basis. A natural sweetener that may cause some people problems is sorbitol, originally derived from the berries of the mountain ash tree. Sorbitol tastes sweet but is not easily absorbed form the gastrointestinal tract and is not easily metabolized. It is a common ingredient of sugarless chewing gums and candies. If you eat a lot of it, you will probably get diarrhea. People with irritable bowel syndrome or ulcerative colitis should avoid sorbitol. Ann Louise Gittleman, in her book, Super Nutrition for Women, writes: In 1977, a Canadian study indicated that when pregnant rats were fed large doses of saccharin, their male offspring developed bladder cancer. As a result, the Canadians banned saccharin and the U.S. Congress ordered warning labels on all saccharin products like Sweet ‘N Low. The national Academy of Sciences in 1978 evaluated the evidence and concluded that saccharin was primarily a promoter of other cancer-causing agents, a cocarcinogen. In the meantime, G.D. Searle developed aspartame, a combination of two amino acids and methanol (wood alcohol) . . . Few long-term studies of the effects of aspartame have been done. However, reports to the Food and Drug Administration and the Centers for Disease Control indicate that, as more people consume the substitute in large quantities, health may be affected. In some circumstances, individuals may be getting high levels of methanol; for example, it is estimated that on a hot day after exercise, an individual drinking three 12-ounce cans of diet cola could easily consume as much as eight times the Environmental Protection Agency’s recommended limit for methanol consumption. The most common complaints are dizziness, disorientation, tunnel vision, ear buzzing, loss of equilibrium, numbing of hands and feet, inflammation of the pancreas, high blood pressure, eye hemorrhages and seizures. Artificial sweeteners can stimulate hunger or cause additive allergies, just as sugar does. In other words, we get the disadvantages of sugar, along with the proven or suspected disadvantages of artificial sweeteners. While thousands of Americans continue to consume aspartame in unprecedented amounts, controversy surrounding its safety lingers. Dr. Richard Wurtman of the Massachusetts Institute of Technology (MIT) has reported that abnormal concentrations of neurotransmitters developed when he fed laboratory animals large doses of aspartame. He believes that the phenylalanine content of the sweetener actually manipulates and alters certain brain chemicals which could initiate behavioral changes and even seizures. He also purports that while small quantities of aspartame may be safe, the cumulative effects of the compound—particularly if consumed with high carbohydrate, low protein snacks—could be serious (Wurtman I, 799-801, Wurtman II, 429-430, Wurtman III, 1060). In spite of serious concerns, saccharine and aspartame packets sit in restaurant sugar bowls all over our country, while in Japan, natural stevia powder enjoys popularity as one of the best and safest non-caloric sweeteners available.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=640) DO WE NEED EXTRA LIVER PROTECTION?
Date:
July 12, 2005 10:15 AM
DO WE NEED EXTRA LIVER PROTECTION? Even if you don’t suffer from any liver disease or don’t abuse alcohol, you may still require the therapeutic effects of Milk Thistle. Everything that enters the liver through the portal vein must be de-toxified and neutralized. Many of us eat diets that are too high in protein, take overthe- counter or prescription drugs, and routinely expose ourselves to radiation and other pollutants. Everything we breath, eat and absorb through our skin is purified and refined in the liver. Some of the more detrimental compounds we ingest that increase the liver’ s work load include:
Dr. Andrew Weil, M.D. author of Natural Health, Natural Medicine says, “High protein diets impose a considerable work load on the digestive system and may contribute to feelings of fatigue and lack of energy.” The problem with protein is that the liver has to work harder to detoxify the body from the nitrogen waste which results when it is metabolized. This compound called ure a has to eventually be eliminated from the body through the kidneys. Most of us are routinely exposed to nicotine, toxins of various kinds and a whole host of synthetic drugs fro m ibuprofen to steroids. Most of us overeat the wrong things and pass up what’s really good for us. High fat, high sugar, high protein diets stress the liver. Overeating, especially overcooked, fatty foods puts added strain on the liver. In addition, lack of exercise has an indirect effect on the liver. When we don’t exercise, an excess of toxins can build up and has to be transformed by the liver. Typically, when we are exposed to chemicals which can injure the liver, the amount of glutathione in the liver d e c reases. When this substance is reduced, the liver becomes susceptible to damage. The Silymarin content of Milk Thistle keeps concentrations of glutathione in the liver elevated by up to 35%.19 The ability of the liver to detoxify the system is largely dependent on the present of glutathione. According to the American Liver Foundation, liver diseases are the fourth leading cause of death up to the age of 65. It is not commonly known that a significant incidence of liver disease exists in this country. In the past, liver disease was only associated with chronic alcoholics. Now, however, liver disease strikes obese people, social drinkers and people who eat poorly. Milk Thistle can help prevent the subtle kind of liver damage any of us may be susceptible to.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=589) Supports Healthy Blood Sugar Levels-Herbally
Date:
July 05, 2005 10:18 AM
Supports Healthy Blood Sugar Levels-Herbally The introduction of refined sugars into the modern diet has had tremendous negative health consequences on world health. For example, diabetes, especially insulin-independent diabetes (Type 2), is growing rapidly in the United States particularly among children. This type is partly due to the inability of insulin to effectively transport sugar to receptor sites and into cells, where the sugar can be metabolized. Instead of being "burned up," sugar builds in the blood, creating a potentially serious health problem. This inefficiency can occur for a number of reasons, including: insufficient insulin production due to pancreas dysfunction (though many Type 2 diabetics produce excess insulin); the inability of insulin to carry sugar to receptor sites; a defect in the insulin; or a defect in the receptor that does not allow for the sugar to be transported through the cell membrane. Even if one does not have diabetes, it is important to maintain healthy blood sugar levels through proper diet, exercise, and weight management. This is especially important in children who were recently found to obtain 14% of their daily calories from sweet drinks (sodas), overtaking white bread as the primary source of total daily caloric intake. Regardless of the reason, a number of botanicals, in addition to key lifestyle recommendations, have been shown in modern research to support healthy blood sugar levels by enhance sugar metabolization. (Cinnamomum aromaticum syn. C. cassia*) is one botanical that has been shown to have a positive effect on potentiating the effects of insulin. *The study referrd to the material used as Cinnamomum cassia. The officially accepted botanical nomenclature has changed and is now Cinnamomum aromaticum. Ancient Spices for Modern health Spices have been used historically to increase metabolism, raise body heat (thermogenesis), improve digestion and assimilation, and potentiate the effects of other substances. For this reason, in many herbal traditions, small amounts of hot pungent spices were added to many traditional compounds. Regarding sugar metabolization, a study by the United States Department of Agriculture (USDA) looked at the potential effects of 49 spices on insulin function (Broadhurst et al. 2000). These researchers found that cinnamon was the most bioactive in directly stimulating cellular glucose metablosim, i.e. the ability of cells to utilize sugar. The same researchers followed up with constituent studies and determined that it was water-soluble compunds in the extract that had this insulin-potentiating effect. This was followed by a clinical trial (60 subjects), also with involvement of the USDA, on the effects of cinnamon for potentiating insulin. The equivalent of 1, 3, and 6 grams (g) of cinnamon powder (approximately 1/4 to 1.5 teaspoons) reduced blood glucose levels 18-29% in 40 days (Khan et al. 2003). There was a significant increase in efficency between the 1 and 3 g doses, but an insignificant increase between the 3 and 6 g doses. One mechanism of action that has been postulated is that cinnamon increases the activity of PI-3 kinase, an enzyme that is critical in regulating the ability of glucose to be transported into the cell, where it can be utilized as energy. In addition to its ability to potentiate insulin, the cinnamon also supported healthy triglyceride and cholesterol levels, both important health benefits in general. There is an additional benefit of using cinnamon for many Americans; like many spices it is a potent thermogenic agent. This means it can be used as a healthy adjunct to a weight loss program that includes dietary modification and proper exercise. The excessive consumption of simple sugars in conjunction with poor diet and sedentary lifestyles can cause unhealthy blood sugar levels while providing themogenic support can have long-lasting health benefits. There have been a number of popular articles on the recent studies. This had led some to ask if crude cinnamon powder can be used with the same effect and safety. This has not been tested. As with all spices, cinnamon is rich in essential oils. Essential oils have beneficial effects, but the insulin-potentiating effect was found to occur in the water extract. This would suggest that many of the oil soluble compunds were lost in the processing. Also, essential oils can be stimulating and irritating, one of the reasons they are generally used in small amounts as flavoring agents. Therefore, it would be best to look for products that contain the water extract to ensure you are delivering the preparation that most closely reflects the preparation used in the studies. Weight Loss & Lean Muscle Mass- An Important Key to Increased Insulin Sensitivity Maintaining healthy weight and increasing lean body mass are key components in the supporting healthy blood sugar levels. Recently it was reported that only two days of inactivity resulted in a decreased level of insulin sensitivity. Therefore, supporting healthy blood sugar levels is extremely important for those wanting to maintain a healthy lifestyle. In obesity, or in those with a significantly higher percentage of body fat over lean muscle (body mass index greater that 25), it is very difficult for insulin to do its job effectively. The reason is quite simple: fat cells can prevent insulin from actually reaching insulin receptor sites; the fat physically blocks the receptor, and the sugar that should have been burned off through cellular function remains in the blood. It is important to know that, in such cases, there is often nothing at all wrong with the pancreas (the insulin-producing organ), the insulin, or the receptor sites. The fat simply prevents insulin and sugar from reaching their target. In many cases, people are over-producing insulin in an attempt to get more sugar to the receptor sites. After awhile, the pancreas can become exhausted and no longer produce adequate amounts of insulin. Therefore, a primary therapy for supporting healthy blood sugar levels is proper weight management through diet and exercise. References Broadhurst CL, Polansky MM, Anderson RA. 2000. Insulin-like biological activity of culinary and medicinal plant extracts in vitro. J agric Good Chem. 48(3):849-852. Khan A, Safdar M, Khan M, Khan K, Anderson R. 2003. Cinnamon improves glucose and lipids of people with Type 2 diabetes. Diabetes Care 26912):3215-3218. Roy Upton is trained in Western and traditional Chinese herbalism, and has been a professional herbalist for 18 years. He is past president and current vice-president of the American Herbalists Guild (AHG) and is also executive director and editor of the American Herbal Pharnacopoeia. an organization dedicated to the development of authoritative monographs on botanicals used in supplements and medicines. Roy is general manager of Planetary Formulas and a memeber of the Standards Committee of the American Herbal Products Association. He is the author of several books, including St. John's Wort and Echinacea in the Keats Publishing Good Herb Series and co-author of the Botancial Safety Handbook, published by CRC Press. Roy lectures and writes extensively. Disclaimer: The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=547) L-ARGININE - For Increased Circulation
Date:
June 29, 2005 10:16 AM
L-Arginine is an amino acid present in the proteins of all life forms. Under normal circumstances your body can synthesize sufficient quantities from your diet to meet your needs, but in times of stress conditions, such as trauma and wound healing, you may not be able to manufacture enough. L-Arginine’s primary function involves the metabolism of protein and nitrogen. But the scientific community recently became excited about arginine’s newfound role as a promoter of cardiovascular health. L-Arginine is the primary precursor to nitric oxide, a small molecule that is responsible for relaxing blood vessels. If you are among the many people concerned about your circulatory health, then L-arginine should be a part of your wellness program. Source Naturals L-ARGININE is available in 500 mg tablets or capsules and the convenient higher potency 1,000 mg tablets. L-Arginine is an amino acid that is found in most proteins consumed in your diet. A small amount is produced in the liver but it is predominantly synthesized in the kidneys. L-Arginine has several roles in the body, such as assisting in wound healing, helping remove excess ammonia from the body, stimulating immune function, and promoting secretion of several hormones, including glucagons, insulin, and growth hormone. It plays an important role in muscle metabolism by working to transport, store and excrete nitrogen. L-Arginine is required by the body to synthesize nitric oxide, which is produced by all tissues of the body, and plays important roles in the cardiovascular system, immune system and nervous system. Nitric oxide supports blood vessel dilation, which may help circulation. Cardiovascular Support L-Arginine is a nitric oxide precursor. Nitric oxide is formed from arginine via the enzyme nitric oxide synthase or synthasetase (NOS). One of its functions is to regulate smooth muscle contraction. Nitric oxide’s effect on blood vessels is the reason nitroglycerine is prescribed for patients with pain that results from inadequate blood flow to the heart. The nitroglycerine is converted to nitric oxide, which relaxes blood vessels and in turn reduces the workload of the heart. Protein Metabolism L-Arginine is a key nutrient in the energy generating Krebs cycle, where it participates in the detoxification of ammonia. Ammonia is a toxic byproduct of energy metabolism. It is converted to urea and eliminated from the body. Any L-arginine not converted to urea enters general circulation, where it is distributed to various tissues and metabolized for other uses such as protein synthesis. A Wellness Revolution – Taking Charge of Your Health Taking personal responsibility for your health is at the heart of the wellness revolution. Mainstream health care has still not caught up to this wellness approach that health food stores have been promoting for decades. Source Naturals is committed to bringing you effective, safe, advanced natural products like L-ARGININE for your lifelong health.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=519) MECHANISMS OF CHITOSAN FAT- BINDING
Date:
June 25, 2005 08:02 PM
MECHANISMS OF CHITOSAN FAT- BINDING The exact way(s) that Chitosan prevents fat absorbtion is not fully understood but a number of experimental observations support two basic mechanisms. The first mechanism involves the attraction of opposite charges which can be compared to the attraction of opposite magnetic poles. The second entrapment mechanism can be compared to the effect of a net. In the first mechanism the positive charges on chitosan attract the negatively charged fatty acids and bile acids binding them to the indigestible chitosan fiber. This mechanism can explain why chitosan reduces LDL cholesterol levels. Our bodies make bile acids in the liver using the cholesterol from LDL. When chitosan binds bile acids it increases the rate of LDL loss thus improving the LDL to HDL ratio. If enough bile acids are bound, the fats are not solublized, which prevents their digestion and absorption. The second mechanism (figure 2) describes a netting effect of chitosan fiber. In this model the Chitosan wraps around fat droplets and prevents their being attacked and digested by lipid enzymes. Fats unprotected by Chitosan are digested and absorbed. The “netting” mechanism has been seen to operate in vivo. 108 Substances that Enhance the Action of Chitosan Fibers can be likened to a tangled-up chain. Fibers must “unravel” in order for them to be of maximum benefit to us. “Unraveling” is especially critical for chitosan because each link has a hook on which to attach lipids. Chitosan can absorb an average of 4 to 5 times its weight in lipids. Reports of numbers above and below this range have also been reported and may well reflect the rate or extent of unraveling that had taken place. Fiber formulations can be prepared that unravel rapidly and swell quickly. These highly effective formulations are called superabsorbants. When certain substances are added to chitosan, its remarkable fat-binding ability can be significantly enhanced. Ascorbic Acid D-Ascorbic acid (erythorbic acid) and L-ascorbic acid are C-vitamins which enhance chitosan’s ability to bind lipids. Combining chitosan with ascorbic acid results in even less fat absorption and greater fecal fat losses.77,108 In one study the addition of ascorbic acid to a chitosan enriched diet increased fecal fat losses by 87 percent and decreased fat absorption by over 50 percent.77 Cholesterol oxides cause lesions in artery walls which predispose blood vessels to collect plaque. These dietary cholesterol oxides profoundly influence the initiation of heart disease.Free radicals can also contribute to the formation of cholesterol oxides which are even more likely to damage the heart. Cholesterol oxides have been found in deep-fried foods, powdered eggs, processed meats and in human blood itself. Consequently, taking antioxidants like ascorbic acid is vital to protect against the cellular damage this type of free radical causes.112 Citric Acid In feeding experiments with animals, adding citric acid to a chitosan enriched diet resulted in a decreased feed consumption.77 The most likely explanation for this effect is that the citric acid may be enhancing the swelling action of chitosan leading to a sense of fullness, producing satiety and appetite suppression. Indoles Indoles are remarkable phytochemicals which have the ability to selectively activate certain Mixed Function Oxidases (MFOs).113 These MFO’s help balance estrogen metabolism and prepare dietary toxins for elimination before they are absorbed. The presence of fiber in the intestines provides a bulk agent to carry the metabolized toxins out of the body. Chelat ed Minerals The very best approach to weight loss is to nutritionally augment food choices with nutrient supplementation. Certain biochemical compounds are essential to promoting vigor during the process of thermogenesis. Chelated minerals act to bolster, support and protect the organ systems of the body.114,115 For example, when fat is burned, heat and energy are released. If a lack of certain minerals exists, energy levels will drop. Minerals help to transport needed nutrients to depleted areas of the body, thereby stemming off the fatigue we so often experience after eating a fatty meal. Even more importantly, free radicals are released whenever fat is consumed and burned and the presence of chelated minerals helps to expedite the removal of these metabolites and facilitate the availability of fuel for energy. Essential Fatty Acids Prostaglandins control and balance many body functions. The dietary building blocks for making prostaglandins are the essential fatty acids (EFAs). The role of prostaglandins in weight loss has been extensively discussed in a recent review.116 EFAs exert profound lipid-lowering effects.They reduce the synthesis of triglycerides and very low density lipoproteins (bad cholesterol) in the liver. EFA supplementation coupled with a low-cholesterol, low-saturated fat in diet produces a complementary effect in lowering serum lipid levels.117 Garcinia Cambogia ( Hydroxy Cit ric Acid) Garcinia Cambogia contains hydroxycitric acid (HCA). This form of citric acid inhibits the liver’s ability to make fats out of carbohydrates.118 Carbohydrates are converted to glycogen stores, not fat stores, giving the body a better energy reserve and an increase in stamina.119 Ephedra And Thermogenisis Thermogenesis means “creating heat.” This is one of the ways our bodies have of burning off excess calories and maintaining a constant weight.120 This is an area of weight management research that is being intensely studied. When we repeatedly yo-yo diet or abuse ourselves by eating too much, our thermogenic ability may be reduced. Numerous animal and human studies have confirmed the benefits of ephedra and methylxanthines in inducing weight loss and restoring thermogenic responsiveness.43,44,121
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=502) Treating and Preventing Age-Related Mental Disorders
Date:
June 25, 2005 11:24 AM
Treating and Preventing Age-Related Mental Disorders Ginkgo biloba may be of great value in cases of age-related mental dysfunction including senility, Alzheimer’s disease and diminished memory. In Paris, P. R. Michil conducted a double-blind study in which 50 patients with moderate senile dementia were given either ginkgo or a placebo. Patients treated with ginkgo extract showed a significant improvement in their mood, sociability, and vigilance. Senility in the elderly is frequently the result of insufficient blood and oxygen flow to brain cells. Anytime this type of insufficiency occurs, short-term memory loss, ve rtigo, headache, malaise or depression can result. An extract derived from ginkgo leaves offers significant hope to anyone who suffers from diminished blood flow to the brain. In another large open trial involving 112 geriatric patients who suffered from inadequate cerebral blood flow, 120 mg. of ginkgo biloba extract was administered. The results showed a significant regression of pre-existing symptoms.5 What this study implies is that so-called “age - related disorders,” including senile dementia, may be caused by reduced blood flow to the brain rather than the actual degeneration of nerve cells. Ginkgo appears to increase oxygen utilization in brain tissue, which also enables neural cells to metabolized sugar more effectively.6
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=450) GARLIC AND CHOLESTEROL LEVELS
Date:
June 25, 2005 10:00 AM
GARLIC AND CHOLESTEROL LEVELS Several controlled studies have conclusively proven Garlic’s ability to lower blood serum cholesterol levels.6 Dozens of these studies conducted throughout the world have compared high fat diets with garlic and without and their resulting cholesterol counts. When Garlic is consistently consumed, the lowest cholesterol levels are obtained.7 Apparently, the allicin compounds in garlic help to block the creation of cholesterol. Consequently, serum-triglycerides and betalipoprotein levels were lowered while HDL levels (good cholesterol) were raised. The way in which garlic accomplished this specific action is not totally understood. What is known is that the presence of Garlic provides a simple restriction in the rise of blood cholesterol and lipid levels. For anyone with a tendency to develop atherosclerosis, these findings are highly significant. When administered in therapeutic dosages, garlic protected the arteries against atherosclerotic lesions. The implications of studies such as this one are that ingesting garlic on a regular basis may have significant value for anyone suffering from heart disease due to hardening of the arteries. Garlic clearly suppresses cholesterol synthesis in the liver by lowering total serum cholesterol. It appears to accomplish this by inhibiting the synthesis of harmful LDL cholesterol which boosts the amount of beneficial HDL cholesterol in the blood. An added bonus of garlic is that some of its chemical components also keep the liver from producing its own cholesterol.8 Laboratory rats whose diets were supple-mented with garlic not only had fewer lipids in their blood and tissue samples, but less cholesterol and triglycerides in their livers as well. Interestingly, the sugar factor plays a role in cholesterol production and garlic can also be of benefit here. Excess sugar is metabolized into materials which are required for the making of cholesterol and other fats. If the diet is high in sugar, triglycerides levels can rise. Tests have shown that when diets high in fat and sugar were supplemented with garlic, the expected rise in blood lipids did not occur.9 Apparently, in some of these tests, aged Garlic extract was the most effective form. Interestingly, in some studies, blood lipids initially rose after taking garlic and then declined. It is believed that because garlic removed fats that were deposited in the tissues into the bloodstream, lipid levels rose temporarily, however, the garlic also helped to metabolize those fats and excrete them from the body.10 Extensive data strongly suggests that garlic is of great value in both the prevention and treatment of cardiovascular disease which is a result of arterial fatty deposits. Using garlic can decrease the phospholipid content of the blood even when the diet is high in saturated fat. This particular action is nothing less than extraordinary. Garlic’s ability to affect a significant reduction in cholesterol appears to be dose-dependent. In other words, the more garlic consumed, the greater the results. Epidemiological studies support this fact and have shown an inverse correlation between cardiovascular disease and garlic consumption in various populations worldwide.11
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=430) Defeat Depression
Date:
June 13, 2005 01:18 PM
Defeat Depression by Cal Orey Energy Times, August 2, 1999 Depression plagues the creative and the mundane. The disparate desperate driven to distress by depression include painters, poets, actors and musicians as well as truck drivers, clerks, electricians and physicists. The victim list encompasses Vincent van Gogh, Emily Dickinson, Audrey Hepburn, Virginia Woolf and Ludwig von Beethoven, as well as millions of other sharers of melancholy misery. More than 17 million American men and women experience depression in one form or another every year, according to the National Mental Health Association (NMHA) in Alexandria, Virginia. This includes the deeply destructive major, or clinical, depression, the wide mood swings of bipolar disorder (manic-depressive illness), and dysthymia, a milder, long-lasting form of emotional suffering. Twice as Many Women In the depression scenario, women suffer twice as much: Two times as many women as men endure clinical depression, reports the NMHA. The mood-deteriorating effects of the hormonal disruptions women are heir to may be partly to blame. According to the National Institute of Mental Health (NIMH), about one of 10 Americans wades through at least one depressive swamp sometime during his or her life. The good news: Research shows that diet and lifestyle can lower your risk of depression. Birth of the Blues Nowadays, mounting evidence suggests that depression may result more from physiological factors than psychological woes. Some of the hidden reasons why you may be depressed include: nutritional deficiencies, exacerbated by overdosing on too much caffeine, sugar, alcohol and high fat foods; allergies; anxiety and chronic stress; and a chemical imbalance in the brain's gray matter. According to the NMHA, people with depression often possess too little or too large a quantity of the neurotransmitters norepinephrine, serotonin and dopamine. Changes in levels of these brain chemicals may cause, or contribute to, clinical depression. The NMHA also reports that an imbalance of melatonin, a chemical made by the body's pineal gland (located at the base of the brain), contributes to a form of wintertime depression called seasonal affective disorder (SAD). This hormone is made at increased levels in the dark. Therefore, the body may oversupply this hormone during winter's shortened daylight hours. Plan B Since the B vitamins are often involved in the production of energy, and a large component of depression may encompass the inability to get out of bed and deal with the world, experts believe that at least some of the signs of depression are linked to B deficiencies. For instance, studies cited in the Encyclopedia of Natural Medicine (Prima) by Michael Murray, ND and Joseph Pizzorno, ND, demonstrate that folate deficiency and lack of vitamin B12 can compromise mental health (Drugs 45, 1993: 623-36; Lancet 336, 1990: 392-5). Inositol: This vitamin is also part of the B vitamin complex, and it, too, has shown its ability to lift spirits. Research work in Israel shows that daily inositol given to 28 depressed patients for four weeks produced an overall positive effect. (Eur Neuropsychopharmacol 7:2, May 1997: 147-55). Inositol is found in whole, unprocessed grains, citrus fruits (except lemons) and brewer's yeast. NADH: Allan Magaziner, DO, in his book The Idiot's Complete Guide To Living Longer & Healthier (Alpha), reports that brain energizing NADH, a metabolite of vitamin B3, enhances the production of the key neurotransmitters dopamine, noradrenaline and serotonin. "In a recent clinical trial," he claims, "nearly all patients given NADH for depression reported improvement in their symptoms and the absence of side effects or adverse reactions." Moody Spotlight Another substance winning the spotlight for its effect on mood is SAM-e: S-adenosylmethionine. In New York on February 24, a symposium coordinated by the American Health Foundation met to hear researchers present information from studies of SAM-e's ability to possibly ease depression. "SAM-e is a natural product. You and I have it but as people age it declines in production in the body. And that's why we believe supplementation in older people is a beneficial means of bringing that back up and helping people that have depression," said the lead symposium researcher, John H. Weisburger, PhD, MD, Director Emeritus, American Health Foundation in Valhalla, New York. Another researcher, Teodoro Bottiglieri, PhD, Associate Professor of Biomedical Studies and Neurology, Director of Neuropharmacology at Baylor University reported: "SAM-e has been shown to enhance brain dopamine and serotonin neurotransmitter metabolism and receptor function. It may also aid in the repair of myelin that surrounds nerve cells. These mechanisms are likely to be responsible for the antidepressant effect of SAM-e." (Bottiglieri is co-author with Richard Brown, MD, and Carol Colman of Stop Depression Now, a report on the powers of SAM-e just published by G.P. Putnam's Sons.) SAM-e was first touted as an antidepressant in Italy in 1973. It's been reported that nearly 40 clinical trials demonstrate its beneficial effects as a natural antidepressant. For instance, an analysis of more than 1000 people suffering depression showed that the effect of antidepressants in patients taking SAM-e was 17% to 38% better than dummy preparations. Conventional antidepressants show a 20% effectiveness rate (Bressa G. Acta Neurol Scand S154, 1994: 7-14). 5-HTP: Another popular supplement to boost mood and relieve depression is hydroxytryptophan. "This medication is actually a brain chemical that is metabolized from tryptophan into serotonin," says Magaziner. And since low serotonin levels have been linked with depression, and certain prescribed medications may up serotonin levels, 5-HTP is in demand. "One of the more impressive studies supporting the efficacy of 5-HTP for depression evaluated 100 people who had previously found conventional antidepressant therapy to be inadequate. Forty-three of these folks reported a complete recovery, and eight showed significant improvement," reports Magaziner. Not only has 5-HTP been shown to work slightly better than drugs known as SSRIs (these include Prozac), he adds, it has fewer side effects than standard antidepressants, too. DHEA: Medical experts also believe that levels of the hormone DHEA (dehydroepiandrosterone) may influence mood. Ray Sahelian, MD, in his book All About DHEA (Avery) reports an interesting study conducted by Dr. Owen Wolkowitz of the Department of Psychiatry, University of California, San Francisco. A group of six depressed middle-aged and elderly individuals who took DHEA found that within a month they had better memory and mood. (Biological Psychiatry 41, 1997: 311-18.) "In addition," adds Sahelian, "other studies have also found that DHEA increases energy levels and a sense of well being." But follow package directions: Some people complain of greater irritability and overstimulation with DHEA, when they take large amounts. Herbal Relief St. John's wort: still the most touted natural therapy for defeating depression. In Europe, 23 clinical studies, reviewed in the August 3, 1996 British Medical Journal, found that this herb, also known as Hypericum perforatum, can be helpful in alleviating cases of mild to moderate depression. The work, which included 757 patients, has shown that hypericum produced fewer side effects than conventional anti-depressants. Although experts have never satisfactorily explained exactly how St. John's wort benefits the brain, some theorize that it boosts serotonin levels. And it can help SAD sufferers. "In a recent study of 20 people with SAD, four weeks' worth of St. John's wort significantly alleviated feelings of depression. Those people who added full-spectrum lights to the treatment program gained an even greater benefit," notes Dr. Magaziner. Valerian: Anxiety and stress, which can cause depression and insomnia, may be helped by this herb, says the prolific Dr. Sahelian in his book Kava: The Miracle Antianxiety Herb (St. Martin's). In 101 Medicinal Herbs (Interweave), Steven Foster reports that "Ten controlled clinical studies have been published on valerian...one of which suggests that valerian should be used for two to four weeks before daily mood and sleep patterns improve." Amino Acid Help Amino acids, the building blocks of protein, may also help improve mood. (For more on protein, see page 65.) These chemicals are used by the body to construct neurotransmitters, brain chemicals that facilitate mental activity. For instance, the amino acid L-tyrosine is necessary for the formation of transmitters adrenaline and dopamine. This substance, therefore, is given to alleviate depression and anxiety. The substance L-dopa which is given to victims of Parkinson's disease is concocted from tyrosine. And several antidepressants alleviate bad moods by boosting the interaction of brain chemicals related to tyrosine. In addition, since tyrosine is used to make adrenaline, this amino acid may be helpful for folks trying to cope with the mood problems related to stress. Another amino acid that experts believe useful for better moods, L-methionine, is used by the body to make choline, a crucial substance for brain function. (Choline goes into the formation of acetylcholine, a neurotransmitter.) Methionine has been given to people suffering from schizophrenia and depression as well as to those with Parkinson's. Methionine plays a number of crucial roles in the brain and body since it helps form other vital proteins. Depressive Smoking For those concerned about preserving a positive mood, researchers are positive that smoking worsens depression. A study at the Department of Behavioral Services at the Henry Ford Health System in Michigan found that daily smokers run twice the risk for major depression compared to those who only smoked occasionally. Unfortunately, the investigators found that not only did smoking seem to lead to depression, depression, in turn, led to more smoking (Archives of General Psychiatry, 2/99). "Smokers who have depression tend to see their smoking become a daily habit and it may be because they use nicotine to medicate their depressed mood," reported Naomi Breslau, PhD, who headed the research. Over a five year period, the researchers looked at about a thousand young people aged 21 to 30. They found that daily smokers generally start smoking in adolescence, and those who report early depression are three times as likely to eventually become daily smokers. If you're feeling down, don't give up hope. Although depression can prove to be a depressingly complicated malady, daily, healthy habits can offset its effects. Getting consistent exercise, dousing your cigarettes and turning to herbal and nutritional help to treat mild depression may defeat those blues.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=329) Vitali-Tea - Tea fits a healthy lifestyle to a T...
Date:
June 13, 2005 09:45 AM
Vitali-Tea by Leah Brinks Energy Times, October 9, 2003 If the research is even only half right, tea fits a healthy lifestyle to a T. Whenever scientists look at a teapot's contents, they find striking health benefits: Heart protection. Reduced cancer risk. Better skin. All of these are apparently in the bag when you choose to drink tea. Tea green, tea black: Which to choose? Actually, both types come from the same plant, Camellia sinensis. Green tea is steamed and dried; black tea is fermented, which allows its darker color to develop. Some lesser-known types include white tea, which is actually green tea that undergoes the most minimal of handling. (Another rare white tea, white cantaloupe, is rich in antioxidants.) Oolong is a tea that falls between green and black in processing and flavor. One increasingly popular tea color, red, is not tea at all, but an herbal brew called rooibos (technically, herbal teas are known as tisanes). This South African plant yields a citrus-flavored beverage high in vitamin C. Other herbs known for yielding flavorful infusions include chamomile, used to promote sound sleep; peppermint, a digestion easer; and rose hips, which, like rooibos, combines healthy vitamin C levels with a delightfully zesty taste. Toxin Blocker The evidence for tea's health benefits has practically boiled over. For instance, researchers at the University of Rochester have found that green tea substances inhibit the action of a molecule irritated by tobacco smoke, a toxin central to tobacco's cancer-causing danger. This action, say the scientists, may be the reasons that smokers who drink tea suffer less cancer (Chem Res Tox 7/21/03). The Rochester researchers found that tea helps protect a cellular molecule called the aryl hydrocarbon (AH) receptor. Ordinarily, AH is frequently disturbed by toxic substances that cause cancer and other illnesses. Tobacco smoke (as well as the pollutant dioxin) interacts with AH to initiate cancer and other problems. But at least two chemicals in green tea-epigallocatechingallate (EGCG) and epigallocatechin (EGC)-interfere with AH's harmful activity. These substances, flavonoids similar to healthful chemicals found in grapes, wine and cruciferous vegetables like broccoli, have been shown to lower cancer risk. "It's likely that the compounds in green tea act through many different pathways," says Thomas Gasiewicz, professor and chair of Environmental Medicine and director of Rochester's Environmental Health Science Center. In the Rochester study, Dr. Gasiewicz and his colleagues found that EGCG and EGC close down the AH receptor in cancerous animal cells and most likely produce the same benefit in human cells. Still to be made clear is how tea is metabolized when the body digests tea, but the Rochester scientists are still peering through their microscopes and teapots to find out. Tea Protection Scientists at the Linus Pauling Institute at Oregon State University have found that drinking green or white tea can significantly lower your risk of colon cancer as well the prescription drug sulindac, which has been shown effective for people at high tumor risk (Carcinogenesis 3/03). "Tea is one of the most widely consumed beverages in the world, and recent upswings in the sales of green tea in the United States can be attributed to reports of potential health benefits against cancer and other chronic diseases," says Gayle Orner, an OSU research associate. "Teas exert significant protective effects in experimental animal models of skin, lung, esophageal, gastric, hepatic, small intestinal, pancreatic, colon, bladder and mammary cancer." While many people today take aspirin and similar drugs that have been shown to lower cancer risk, this study shows that drinking tea and taking low doses of these drugs, called NSAIDs, can reduce the risk even further. (High doses of NSAIDs, while protective against colon cancer, can cause internal bleeding.) "These are pretty exciting results," Orner says. "What's especially significant is that as far as we can tell consumption of tea has none of the side effects of NSAIDs, which can be severe, including bleeding, ulcers and even death." In this research on animals, use of tea dropped the risk of cancer by about two-thirds. According to the lab results, drinking about three large cups of tea a day should provide significant cancer protection. Based on research in Japan that looked at how green tea lowers the risk of stomach cancer, the Linus Pauling scientists urge plenty of tea drinking: "The more the better." Tea Surprise Studies show that nations of tea drinkers have less trouble with their hearts than residents of places where tea is hardly ever brewed. And now research is starting to zero in on the substances in tea that benefit heart health. A study of 240 Chinese men and women who have high cholesterol has found that chemicals in tea can significantly drop harmful cholesterol (Arch Int Med 6/23/03). "Personally, I was very surprised," says David J. Maron, MD, professor at the Vanderbilt University Medical Center, lead author of the study. "I expected, if anything, a very slight cholesterol-lowering effect. But what we saw was a 16% reduction in low density lipoprotein (LDL) cholesterol." LDL cholesterol is known as "bad" cholesterol because it can increase your risk of heart disease. The researchers in this study gave people extracts of green and black tea enhanced with theaflavin, an antioxidant also found in green tea. In the future, if past results are any indication, tea's rich supply of beneficial chemicals will continue to pleasantly surprise researchers with even more benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=317) R-Lipoic Acid - Fulfilling the Potential of Lipoic Acid
Date:
June 04, 2005 02:23 PM
Lipoic acid may be the body’s most versatile nutrient. Its critical importance for health is scientifically documented. Not only is it a powerful antioxidant, it supports healthy sugar metabolism and liver function, and is integral to energy generation, which affects all biological functions. But few know that the commonly available form, alpha lipoic acid (ALA), is not the same compound that occurs naturally in our bodies. ALA is a 50/50 combination of natural form r-lipoic and synthetic s-lipoic acid—and the synthetic form may actually block the activity of r-lipoic acid, resulting in a weaker product. Because it is the natural form, r-lipoic acid is better absorbed and safely metabolized. And it is up to 10 times more effective at producing cellular energy, according to in vitro research, and may be a more potent antioxidant. Source Naturals, the science company, is proud to be one of the first to offer this breakthrough nutrient: R-LIPOIC ACID R-Lipoic Acid: Key to Cellular Energy Generation Plants capture solar energy in their carbohydrates. In a reverse process called oxidation, animals extract that energy. R-LIPOIC ACID is a vital link in the metabolic pathway that gives us the power to move and the energy of intelligence. R-LIPOIC ACID is synthesized in the mitochondria, the tiny power plants inside every cell that produce energy in the form of ATP. It is safely metabolized and up to 10 times more effective than other forms of lipoic acid in mitochondrial ATP production, according to an in vitro study. Supports Glucose Metabolism Human and animal studies show that R-LIPOIC ACID can increase glucose uptake by muscle and nerve cells. By enhancing sugar metabolism, R-LIPOIC ACID may protect cells from glycation. In this detrimental process, excess glucose reacts with proteins to create tough crosslinked bonds that damage vital proteins, including the myelin sheath of neurons and the lens of the eye. Scientists believe glycation is a major source of tissue degradation and cellular aging. Collagen, another important protein, is also subject to crosslinking, which inhibits the flexibility of blood vessel walls—one of the most important indicators of cardiovascular health. Increases Antioxidant Protection R-LIPOIC ACID also neutralizes the harmful byproducts of glucose metabolism, free radicals. The body synthesizes barely enough R-LIPOIC ACID for its metabolic needs, and this decreases with age. As mitochondrial energy production becomes less efficient, more free radicals are generated. R-LIPOIC ACID protects cells, particularly in the mitochondria, where most oxygen damage occurs. R-LIPOIC ACID is a leading component of the body’s antioxidant network. Unlike other antioxidants, it is water and fat-soluble, so it neutralizes a greater number and broader range of free radicals, providing more protection. In animal studies, R-LIPOIC ACID slowed the aging process, which may be the result of cumulative oxidative damage. Lipoic acid, known as the “universal antioxidant,” is a strong antioxidant in its own right, but it also directly recycles vitamin C and indirectly recycles vitamin E for continued use. And R-LIPOIC ACID is more efficient than other forms of lipoic acid at increasing levels of the key antioxidants, CoQ10 and glutathione. Commercial alpha-lipoic acid is 50% synthetic s-lipoic acid, which can interfere with natural form R-LIPOIC ACID when both forms compete for binding sites. Tests showed 40% better absorption by R-LIPOIC ACID, as measured by plasma concentration levels. Integral to Your Wellness Program Because it is central to such critical functions as energy generation, antioxidant protection, anti-glycation activity, and liver support, R-LIPOIC ACID belongs at the center of your wellness program. Source Naturals is happy to join forces with your natural foods retailer in bringing you this advanced nutrient.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=190) Cholestrex - Lower Cholesterol with Source Naturals Supplements
Date:
June 01, 2005 10:41 AM
Our lives depend on an uninterrupted flow of blood throughout the 60,000 miles of arteries, veins, and capillaries that bring vital nourishment to our cells. Our bodies have complex chemical strategies to maintain and repair blood vessel walls. Cholesterol is an important part of the process. However, too much cholesterol in the bloodstream can have serious consequences for our well-being. By understanding how nutrition affects blood cholesterol, we can gain valuable control of our health. Source Naturals CHOLESTREX has been formulated to provide the nutritional support that we need to maintain healthy cholesterol levels. SINCE DOCTORS FIRST DISCOVERED that cholesterol was the primary ingredient in the sticky deposits that clogged their patients’ arteries, scientists have gained a thorough understanding of cholesterol’s role in our health. Essential to human and animal life, cholesterol is part of every cell in the body. Because cholesterol is so important, the liver synthesizes from 1 to 2 grams of it each day. In addition, we get about another 500 mg from the foods we eat. Problems occur when too much cholesterol gets into the bloodstream. Today, it’s estimated that over 50 million adults in the United States have cholesterol levels that are too high. The body’s processes to manage excess cholesterol depend upon a lifestyle that includes exercise, stress reduction and proper nutrition. Source Naturals Cholestrex is designed to deliver a comprehensive combination of nutrients known to support a healthy blood vessel system – and keep the life stream flowing.
The nutrients in CHOLESTREX are known to support a healthy blood vessel systemCholesterol: What It Is Cholesterol is a solid waxy substance, technically classed as a “sterol.” Cholesterol enables our cell membranes to maintain their integrity. It is the basic raw material from which the body makes steroid hormones, which include the sex hormones. Cholesterol is the primary component of bile salts that the liver creates to help us assimilate fats, fat-soluble vitamins and essential fatty acids. The liver also uses bile to rid itself of stored toxins. Our skin contains large amounts of cholesterol, making it resistant to the absorption of water-soluble toxins. Even the brain is 7% cholesterol (dry weight).
Blood vessel walls cover a surface area of half an acre and are under constant pressureCholesterol in the Blood Because it’s not water-soluble, cholesterol must be attached to a carrier molecule in order to be transported in the bloodstream. The liver manufactures two types of carrier molecules for cholesterol, LDL and HDL. LDL (low density lipoprotein) molecules carry cholesterol from the liver out to cells of the body. One of its functions is to repair damaged cells, including those of the artery walls. LDL is primarily made up of saturated fats, (meat fats, butter, etc.). HDL (high density lipoprotein) molecules transport cholesterol and fatty acids from body tissues back to the liver for disposal. HDL helps remove excess fat and cholesterol from the bloodstream. HDL is composed of liquid fats (most vegetable oils). It’s crucial to have a proper balance between LDL and HDL cholesterol. High LDL – a sign that the body has too much fat – is a threat to the health of blood vessels, because excess LDL cholesterol may accumulate in damaged areas of vessel walls. These “fatty streaks” are the beginning stage of artery blockage.
The oxidation of LDL cholestrol is at the heart of the problemCholesterol and Artery Damage The walls of the blood vessels cover a surface area of half an acre and are under constant pressure. Of all the blood vessels in the body, the coronary arteries are under the greatest stress. Named for the Latin word for crown (corona), they sit directly on the heart muscle and must continually expand and contract with every heartbeat. That’s 100,000 times each day. This constant squeezing can cause small lesions in the artery wall. This triggers a repair process where LDL cholesterol comes in to patch up the damage. Recent research has found that the crux of the problem is the oxidation of LDL cholesterol. Rich in fatty acids, the LDL molecule becomes permanently altered when oxidized by free radicals (overreactive molecules that steal electrons from other molecules). These rancid, oxidized LDL molecules are no longer recognized by the body, so they’re attacked by immune system cells. These immune cells become bloated with the oxidized lipids, accumulate in artery lesions and create plaque in blood vessels. Why is LDL cholesterol being oxidized? First of all, there’s too much of it in the blood, while not enough HDL. Secondly, the blood doesn’t have enough antioxidants to neutralize free radicals. The ingredients in Source Naturals Cholestrex address these specific problems in several ways. Cholestrex also provides nutrients that protect and strengthen blood vessel walls.
In the typical American diet, 95% of the cholesterol meant for removal is reabsorbedCholestrex Has It All Vitamin C helps maintain the health of artery walls because it’s the key building block for collagen and elastin, the primary constituents of blood vessels. Copper is required by the enzyme that weaves together the fibers of collagen and elastin into the matrix that makes vessel walls both tough and flexible. As an antioxidant, vitamin C scavenges free radicals in the blood plasma and also regenerates vitamin E within the LDL molecule. Vitamin E has a critical role as the primary protector of LDL, preventing its oxidation. One molecule of vitamin E can protect 200 molecules of polyunsaturated fatty acids from free radical damage. GTF Chromium is involved in insulin activity and the normalization of blood sugar. Excess simple sugars are converted to triglycerides, the blood fats which can accumulate in artery walls. Lecithin is a component of HDL that emulsifies excess blood fat so it can be more readily transported in the bloodstream to the liver, where it’s metabolized. Vitamin B3 (niacin) assists in the metabolism of fats, and puts an electric charge on red blood cells so they repel each other, which prevents blood clumping. The amino acid, L-Arginine, works to lower serum cholesterol and triglycerides by inhibiting fat absorption.
Beta sitosterol neutralizes incoming dietary cholesterolThe Body’s Cholesterol Removal System HDL molecules carry cholesterol from tissues throughout the body back to the liver, where it is incorporated into bile salts. These bile salts are sent to the intestines, where they combine with fiber for excretion. One problem with the typical American low fiber diet is that 95% of the bile-bound cholesterol is reabsorbed. Since this is the body’s primary pathway for ridding itself of excess cholesterol, another strategy incorporated into Cholestrex is to maximize the production of bile salts and minimize their reabsorption by increasing levels of fiber. Fiber is a key element of Cholestrex. Its four types of soluble fiber bind with bile salts that are laden with cholesterol to ensure their excretion from the body. Oat Bran & Fiber, Grapefruit Pectin, Psyllium Seed Husks and Alfalfa Seeds also absorb cholesterol from our food, thereby lowering total blood cholesterol. Alfalfa seeds are considered a blood purifier. Beta sitosterol, a plant equivalent of cholesterol, binds to sites in the intestines that would otherwise absorb cholesterol. Cholestrex provides a daily total of 300 mg of beta sitosterol which may, by itself, neutralize 200 to 300 mg of incoming dietary cholesterol by preventing its absorption. Vitamin C, among its many other vital roles, is the key factor in activating an enzyme that will increase the liver’s conversion of cholesterol into bile salts. CHOLESTREX uses bioactive mineral ascorbate forms of vitamin C that will not irritate the digestive system. Working in conjunction with the fiber in CHOLESTREX, Calcium increases HDL, while lowering total serum cholesterol. Cholestrex–Intelligent Nutritional Support Our generation is fortunate to witness the remarkable progress made by modern science in understanding the body’s complex biochemical processes. As we realize the vital connection between nutrition and cholesterol levels, we are empowered to improve our health and vitality beyond previous standards of wellness. Source Naturals CHOLESTREX. For you and the ones you love.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=132) CALCIUM D-GLUCARATE - Estrogen Detoxification
Date:
June 01, 2005 09:25 AM
From the womb to the tomb, we are subject to the effects of estrogen, the potent female hormone that shapes our lives. Variations in estrogen levels can have a dramatic effect on our cellular development. Source Naturals is proud to introduce a nutrient that may help the body remove excess estrogen, thereby giving relief to estrogen-sensitive tissues. Calcium D-glucarate is currently the subject of numerous clinical studies. It is proving to have great potential for addressing health concerns closest to our heart. One of life’s most delicate balancing acts is found in the ebb and flow of hormones that is constantly taking place in the human body. These messenger chemicals are fundamental to the process of life. Produced by endocrine glands, hormones travel throughout the body, communicating with each other as they direct cellular activity. For example, the hypothalamus gland monitors hormone levels in the body. It signals the pituitary gland, advising it to send messages to the ovaries to either produce or stop producing estrogen. Estrogen is an extremely powerful hormone whose activity can be measured in parts per trillion. Therefore, it doesn’t take much to create an imbalance. Like all hormones, estrogen communicates with a cell by docking to a particular receptor site on that cell’s membrane. If there is an excess of these estrogen-sensitive receptors, or an excess of circulating estrogen in the bloodstream, normal cellular metabolism can be altered. Another problem is that estrogen receptors are not very particular; they will accept many chemicals – both natural and synthetic – other than estrogen. How the body removes excess estrogen One of the processes by which estrogen and estrogenic compounds are metabolized and broken down is through glucuronidation. In the liver, they’re bound to glucuronic acid and then excreted in the urine or feces. This process can be disrupted by an enzyme called beta-glucuronidase, which is found in the gastro- intestinal tract. It frees the bound-up estrogen or estrogenic compound, releasing it to be reabsorbed back into the bloodstream – to again affect cells. Obviously estrogen is needed by the body; however, too much can lead to cellular disruption. Since it can be very difficult to avoid the estrogenic chemicals rampant in our environment, another strategy is needed, and that is to reduce their negative effects by supporting the body’s natural ability to remove excess estrogen and other hormones and toxins. Calcium D-glucarate and hormone metabolism The removal of excess estrogen can be increased by a natural substance called Calcium D-glucarate (CDG), because it inhibits beta-glucuronidase activity in the body. This means that estrogen bound for excretion stays bound, and the total estrogen load on the body is reduced. In clinical trials, tissues that are sensitive to excess hormones – such as breast, liver, and lung – have been shown to respond favorably to CDG. In addition to estrogen and estrogenic compounds, CDG helps promote excretion of other hormone metabolites as well as cellular toxins and steroids. CDG is made naturally in small quantities in the body; it is also found in a variety of fruits and vegetables: oranges, broccoli, carrots, spinach, and apples. Vitamin A has been shown to have a synergistic effect with CDG. One 500 mg tablet of Source Naturals CALCIUM D-GLUCARATE is equivalent to the phytonutrient activity found in 82 pounds of fresh fruits and vegetables. The suggested use for preventative health maintenance is 3 to 4.5 grams per day. No toxicity has been found with its usage. Phytonutrients also help reduce estrogen exposure Another strategy to reduce the effects of excess estrogen is to increase the intake of plant estrogens. This helps for two reasons. First, by occupying estrogen receptor sites, these natural estrogenic compounds block synthetic estrogens from attaching to these sites. Second, phytoestrogens only mildly activate receptors. One of the best phytoestrogens is genistein, the isoflavone in soybeans responsible for soy’s beneficial influence on the human body. Increased intake of genistein and/or soy is being recommended by many health professionals, especially for post-menopausal women. Please see Source Naturals product literature on GENISTEIN as well as MENOBALANCE, our nutritional menopause formula with genistein and black cohosh. Both are part of our advanced line of nutritional support for women As new research sheds light on the importance of proper hormone balance to our health, it’s vital to protect ourselves from the increased burden of estrogen that we are encountering today. Source Naturals CALCIUM D-GLUCARATE is a timely nutrient that can make a real difference in our lives.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=126) Attentive Child - Enhances Mental Concentration ...
Date:
May 31, 2005 05:14 PM
Most children are creative, energetic and spontaneous, but sometimes they don’t focus on requested activities. Sometimes kids find it difficult to apply themselves to the task at hand. Your child’s brain also may work differently than most people’s brains— just like the 5% of the population that is left-handed. Most people think an ultra-active child means an active brain, but active children may actually need a boost in brain metabolism. Source Naturals ATTENTIVE CHILD is a Bio-Aligned Formula™ designed to address the multiple systems that affect children’s ability to focus: neurotransmitters and brain metabolism, nerve cell communication, antioxidant defense, and essential fatty acid metabolism.
Comprehensive Brain Support Parents are looking for a safe and natural product to support their children’s ability to focus. Source Naturals studied the research and created an experiential formula, based on the latest breakthroughs in cerebral and nervous system biochemistry. Each ingredient in ATTENTIVE CHILD plays a role in brain and nervous system structure or functioning, or is involved in important biochemical pathways. DMAE, a substance normally found in the brain, boosts brain metabolism and has been shown to enhance concentration. L-Aspartate is an amino acid neurotransmitter that stimulates brain activity. Research has shown that some ultra-active children may have special dietary needs for magnesium, zinc and DHA (docosahexaenoic acid). Magnesium is necessary for the transmission of nerve signals, and, along with zinc, for the processing of essential fatty acids into other vital biochemicals. DHA is an essential fatty acid that is very important for cerebral development and effective communication between nerve cells in the brain. Lecithin contains four phospholipids—fatty acid building-block molecules in nerve cell membranes. Phosphatidylserine, in particular, is vital in nerve cell communication and the electrical activity of the brain. Grape seed extract is a plant-derived antioxidant that protects the integrity of fatty acids in nerve cell membranes. ATTENTIVE DHA™ in Tiny Kid Caps™ The ATTENTIVE CHILD formula can be supplemented with additional DHA. ATTENTIVE DHA Kid Caps are available in easy-to-swallow, small oval softgels, each containing 100 mg of DHA. For children who can’t swallow caps, simply pierce the gel and mix the oil with food. Sweeteners with Low Impact on Blood Sugar The delicious sweetand- tart taste in ATTENTIVE CHILD wafers comes from natural flavors, specially manufactured without sugar for Source Naturals. Unless specified, most flavors in other products contain maltodextrin, a sugar with a high glycemic index. The ATTENTIVE CHILD wafer itself is sweetened with crystalline fructose (natural fruit sugar) and xylitol (a naturally occurring sweetening agent found in many fruits and vegetables). These select natural sweeteners have a very low glycemic index—so ATTENTIVE CHILD will taste great to your child, but have little effect on blood sugar levels. We recommend carefully reviewing the labels of other products. They may contain honey, glucose, sucrose, maltodextrin, and maltose—all of which have moderate-tohigh glycemic indexes. In addition, maple sugar, molasses, malt syrup, rice syrup, and beet sugar contain varying amounts of high-glycemic-index sugars, which can set off blood sugar fluctuations that may affect concentration. Beware of children’s nutritional bars designed to enhance focus and concentration. Most have over 20 grams of sugar per bar. In contrast, each serving of ATTENTIVE CHILD contains only two grams of crystalline fructose, which has little effect on blood sugar. Glycemic Index of Various Sweeteners
The glycemic index is a ranking of foods based on their immediate effect on blood glucose levels. It measures how much your blood glucose increases over a period of two or three hours after intake. The higher the glycemic index (GI), the greater the fluctuations in blood sugar. Sweetener Glycemic Index† *sweeteners used in ATTENTIVE CHILD ™ †based on rate of 100 for glucose ††for information, see website www.wcommerce.com Lifestyle Strategies for Your Child You can help your child concentrate on schoolwork, chores and other challenges. Start with ATTENTIVE CHILD and ATTENTIVE DHA, and then incorporate a healthy lifestyle and nutrition routine. Physical Health Have your child’s overall health checked by a welltrained holistic health care professional, such as a naturopathic physician. It is particularly important to examine the functioning of your child’s thyroid gland (the master regulator of the body’s metabolism, which influences mood and energy level), and blood sugar metabolism (the brain depends on a steady supply of glucose to function properly, particularly when you are trying to concentrate). Nutritional Health: Feeding the Brain Help your child maintain a steady supply of energy and brain fuel by providing a balanced diet. Small, frequent meals are preferable since they dispense a steady level of glucose to the brain. Include foods high in the amino acid tyrosine, a precursor to neurotransmitters that support an alert state. It is found in protein foods, such as meat, poultry, beans, tofu, lentils and seafood. Also include complex carbohydrates such as whole grains, fruits and vegetables, which are metabolized slowly and yield a steady supply of glucose. The simple sugars found in candy, cookies, sodas and other processed foods can lead to a rapid rise in blood sugar levels, followed by an abrupt decline, and should be discouraged. It is important to include essential fatty acids, especially omega-3 fatty acids, which are abundant in the brain and essential for its development and normal functioning. Supplement with ATTENTIVE DHA, and encourage your child to eat cold-water fish, such as salmon. Avoid the hydrogenated fats found in processed foods and margarine, as well as chemicals and food additives. A nutrition program consisting of fresh, unprocessed natural foods is the healthiest choice for everyone. Lifestyle Health Some experts believe extended time watching TV and playing video games does not support optimal health or school performance. EEG studies have shown that these activities decrease brain activity rather than activating the brain. Encourage your child to spend time in outdoor physical recreation and in creative, challenging activities. Supplement with ATTENTIVE CHILD and ATTENTIVE DHA ATTENTIVE CHILD is available in bottles of 30 & 60 chewable wafers. ATTENTIVE DHA Kid Caps (algal-source Neuromins®) are available in 30- & 60-softgel bottles. References Amen, D. Windows into the....Mind. Fairfield, CA: MindWorks Press, 1997. Foster-Powell, K. & Miller, J.B. 1995, International tables of glycemic index. Am J Clin Nutr. 62:871S-93S. Natah, S.S. et al. 1997. Metabolic response to lactitol and xylitol in healthy men. Am J Clin Nutr. Apr; 65(4):947-50. Schmidt, Michael. Smart Fats. Berkeley: Frog, Ltd., 1997. Sears, William. Boston: Little, Brown & Co., 1998.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=120) Androgens and 4-Diol and 4-Dione conversion to Testosterone...
Date:
May 17, 2005 04:47 PM
The androgens 4-androstenediol and 4-androstenedione are natural testosterone precursors. The biosynthesis of testosterone takes place within the testicular Leydig cells in two metabolic pathways. During the progesterone-pathway (.delta.-4 pathway), pregnenolone is metabolized to progesterone by the 3-.beta.-hydroxy-steroid deydrogenase and an isomerase. Progesterone is then changed to 17-.alpha.-hydroxyprogesterone by the 17-.alpha.-hydroxylase and C.sub.17C.sub.21-lyase to androstenedione, then to testosterone by reduction of the 17-keto-group by 17-.beta.-hydroxy-steroid dehydrogenase. The DHEA-pathway (.delta.-5 pathway) leads from pregenolone to 17-.alpha.-hydroxypregnenolone to dehyroepiandrosterone (C.sub.17C.sub.21-lyase), to 5-.delta.-androstenediol. See FIG. 4; Wichmann et al., 83(3) EXP. CLIN. ENDOCRINOL. 283-290 (1984). As a testosterone pro-hormone and metabolite, 4-androstenedione may be used by athletes and bodybuilders to improve muscle mass. Levels of .delta. 4-androstenedione increase significantly with moderate exercise in healthy men. Velardo et al., 97(1) EXP. & CLIN. ENDOCRINOL. 99-101 (1991). Additionally, supplementation with 4-androstenedione has been known to produced elevations in serum testosterone. Mahesh et al., 41(3-8) J. STEROID BIOCHEM. MOL. BIOL. 495-513 (1992). 4-androstenediol is also metabolized into testosterone and is produced by conversion of dehyroepiandrosterone. Inaba et al., 13(2) ENDOCRINOLOGIA JAPONICA 160-72 (1966). It was first shown to produce elevations in human serum testosterone levels in 1965, and this was also demonstrated in in vitro studies in animals (Kundu, 6(5) STEROIDS 543-51 (1965) and human fibroblast cultures. Faredin et al. 32(2) ACTA MEDICA ACADEMIAE SCIENTIARUM HUNGARICAE 139-52 (1975). Supplementation with 4-androstenedione, 4-androstenediol, and 19-nor-4-androstenedione has been studied to determine whether a rise in testosterone is produced. Uralets et al., 23 ANAL. TOXICOL. 357-366 (1999). Testosterone is excreted in the urine unchanged and is metablized through 5.alpha.- and .beta.-DHT as 5.alpha.- and .beta.-androstanediol, while androstenedione is similarly excreted as androsterone and etiocholanolone. Both the final excreted steroid and the intermediaries stanediones and DHT intraconvert so that androsterone, 5.alpha.- and .beta.-androstanediol and etiocholanolone are seen in urine. Supplementation with 4-androstenediol produced a 10-fold greater urine testosterone concentration than 4androstenedione. (Uralets, 1999)
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=65) DHEA and people with panhypopituitarism (lack of adrenal and ...
Date:
May 17, 2005 04:43 PM
The testosterone precursors are normally metabolized from dehydro-epiandrosterone (DHEA). This has been studied in people with panhypopituitarism (lack of adrenal and gonadal steroids) by administering 50 mg or 200 mg of DHEA. This induces an increase of both steroids to supraphysiological plasma levels and a small increase of delta 5-androstenediol. In contrast, the increase of plasma delta 4-androstenedione was significant and dose dependent. DHEA was also converted into testosterone. The administration of a 50 mg dose of DHEA restored plasma testosterone to levels similar to those observed in young women. The 200 mg dose induced an important increase of plasma testosterone, slightly below the levels observed in normal men. The increase of plasma dihydrotestosterone levels was small at both doses of DHEA, in contrast with the large conversion of DHEA into androsterone glucuronide and androstanediol glucuronide. Finally, DHEA administration induced a significant and dose dependent increase of plasma estrogens and particularly of estradiol. Young et al., 82(8) J. CLIN. ENDOCRINOL. & METABOL. 2578-85 (1997).
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=64) Under-Reported (and Underappreciated) Cholesterol control.
Date:
May 12, 2005 10:00 AM
Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Controlby Richard Conant, L.Ac., C.N.Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat. The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol. Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid. The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.) Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them. Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established. How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a closer look. In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides. Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels." Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions. Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state. Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves. Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6 Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels. When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long. There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12 We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health. Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger. The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E." It would be a tremendous service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E. References 1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82. 2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18. 3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28. 4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34. 5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619. 6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86. 7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980. 8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45. 9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93. 10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26. 11. Welsh, A.L. Ede, M. Inositol hexanicotinate for improved nicotinic acid therapy. International Record of Food Medicine 1961;174(1):9-15. 12. "Inositol hexaniacinate" (Monograph). Alternative Medicine Review 1998;3(3):222-3. 13. Serbinova, E., et. al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha tocotrienol. Free Radical Biology and Medicine 1991;10:263-275. 14. Qureshi, N. Qureshi, A.A. Tocotrienols: Novel Hypercholesterolemic Agents with Antioxidant Properties. in 'Vitamin E in Health and Disease' Lester Packer and Jürgen Fuchs, Editors. 1993; New York: Marcel Dekker, Inc.
Control Cholesterol with the following Supplements
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=30) 
Date:
May 12, 2005 09:33 AM
Keeping the Intestines Healthy"Friendly Bacteria" Therapy Breakthroughby Richard Conant, L.Ac., C.N. Ninety percent of the cells found in the human body are not of human origin. No, this does not mean we are all products of some sinister alien experiment. The human body is made up of about 10 trillion cells. This huge number is dwarfed by the bacteria we all carry around in our intestinal tracts. The lower bowel is a campground for roughly 100 trillion bacteria, single-celled plant organisms that can be seen only through a microscope. When we enjoy good intestinal health, the bulk of these bacteria are beneficial. Known as "friendly flora," these tiny guests help digest our food by breaking down undigested proteins, fats and carbohydrates. The friendliest of the friendly bacteria are the "lactobacilli," so named because they produce lactic acid in the bowel, by fermenting carbohydrates. This lactic acid production is profoundly important for keep the intestines healthy. And good intestinal health is the foundation of overall health. How do we maintain a thriving population of lactic acid-producing bacteria in the gut? First introduced into the human body through mother's milk, lactobacilli are somewhat fragile. Stress, poor diets, and antibiotics can kill them off. They should be replanted fairly regularly throughout life. One way to do this is through consumption of cultured milk products such as sour milk, kefir and yogurt, which contain live lactobacilli. They can also be consumed in dietary supplements, but this may or may not be a reliable route. Bacterial products do not keep very well on the shelf, they require refrigeration, and are largely destroyed on the trip from the mouth to the gut by our own digestive juices. Introducing Lactobacillus sporogenes- a revolutionary new friendly bacteria supplement. This article will focus on one particular species of lactobacilli, a relatively unknown member of the family called Lactobacillus sporogenes. This lactic-acid producing bacteria may prove to be one of the most practical forms for use in supplements, thanks to a unique property not shared by the more well-known friendly flora such as acidophillus. L. Sporogenes is a spore-forming bacteria. Safely enclosed within a spore coat that protects it from the environment, L. sporogenes is resistant to heat, oxygen and digestive acids. Once L. sporogenes reaches the intestines, its spore coat dissolves, freeing the bacteria to multiply and churn out the beneficial lactic acid. (The spore coat, made up of a calcium-protein-carbohydrate complex, is harmless).1 The difficulty of keeping friendly bacteria supplements alive is an ongoing problem for manufacturers of these products. Studies have analyzed various commerical products claiming to contain acidophilus and found they often contain few live bacteria.2,3 L. Sporogenes is naturally microencapsulated; this insulates it from the gauntlet through which friendly bacteria in dietary supplements must pass.1 Autointoxication-Poisoning by Bacterial Toxins The intestinal tract may also play host to pathogenic, or disease-causing bacteria. These "unfriendly flora" cause putrefaction and release injurious toxins into the lower bowel. This healthy picture is all too common, and has long been concern of wholistic health practitioners. The concept of "autointoxication," poisoning of the body by intestinal toxins, was popular among doctors in the late 19th and early 20th centuries. An editorial on the dangers of autointoxication which appeared in the June 3, 1893 issue of the Journal of the American Medical Association (JAMA) declared that "most likely a large majority of chronic diseases take their origin from this cause."4 The famous Russian physician Eli Metchnikoff pioneered the use of lactobacteria for preventing autointoxication and restoring bowel health. His landmark work 'Prolongation of Life' sparked interest in lactobacilli as a food supplement.5,6 Naturopathy, widely practiced during the early twentieth century, has always stressed the fundamental importance of bowel cleansing. With the advent of so-called "scientific medicine," naturopathy slipped into decline, and the concept of autointoxication was discredited. Over the last thirty years or so, this has changed. Naturopathic medicine has rebounded, and the importance of bowel health is once again recognized. A paper published in the New England Journal of Medicine in 1964, while opining that autointoxication "was exploited by quacks and faddists" in the early 1900's concedes that "the concept of autointoxication must now receive serious consideration."7 Leaders in the rebirth of natural medicine such as Dr. Bernard Jensen have helped educate the public about the importance of keeping the bowels healthy through regular use of lactobacilli. Jensen is well-known for his extensive studies of regions such as the Hunza Valley in Pakistan where people commonly live well over one hundred years. Jensen and others have noted that the consumption of fermented dairy products containing lactobacilli is a common dietary practice in these areas. Their observations have contributed to the popularity of friendly bacteria supplements. At the same time, clinical research has provided ample evidence of the beneficial effects of lactobacteria supplementation.5,9<.sup> Eubiosis-Keeping a Healthy Bacteria Population in the Intestinal Tract In his book 'Tissue Cleansing Through Bowel Management, which contains a wealth of valuable wisdom on intestinal health, Dr. Jensen writes, "Where health and vitality are found, we invariably find the friendly and beneficial microbes ... To a large extent the flora in the bowel determines the state of health in an individual."8 In a healthy bowel the friendly flora make up the bulk of the bacteria population. The unfriendly, disease-causing organisms are in the minority. The good bacteria keep them firmly under control. This healthy microbial balance in the gut is called "eubiosis." Life in our modern industrial society is hardly favorable to eubiosis. Residents of the Hunza Valley lead unhurried lives in a pristine, pollution-free environment. They grow their own food in fertile, nutrient-rich soil, work close to the landÐand consume lactic-acid producing bacteria on a daily basis. For the rest of us who cannot hope to enjoy this enviable lifestyle, eubiosis is something we should never take for granted. This means taking proactive steps to plant the seeds of health in our intestinal garden, by using a viable friendly bacteria supplement. Supplements which help to populate the intestinal tract with friendly bacteria are known as "probiotics." The term "probiotic" literally means "for life.' (In contrast, "antibiotic" means "against life.") Probiotics restore the natural state of "eubiosis" that is so very important for health and longevity. L. Sporogenes-an ideal probiotic Not every species of lactobacilli qualifies as an effective probiotic. As noted above, many do not survive processing, storage and passage through the digestive system very well. The following attributes make L. Sporogenes an ideal probiotic supplement:1,10,11 1) Naturally microencapsulatedÐstable at room temperature and can be stored unrefrigerated for long periods without loss of viable organisms. 2) Tolerates heat, stomach acid and bile, allowing it to successfully travel into the lower bowel. 3) Non-pathogenic, has only beneficial effects on its host. Has similar characteristics as acidophilus: prefers a mild acid environment; produces lactic acid, digestive enzymes, etc. 4) Readily multiplies in the human gut. In the stomach, the spore coat absorbs moisture and begins to swell. Upon reaching the small intestine, the bacteria cells germinate and begin to multiply, doubling in number every 30 minutes. 5) Produces enzymes which help digest protein, fats and carbohydrates. These enzymes include lactose, the enzyme that digests milk sugar.12 6) Creates a favorable environment (mildly acidic) in the gut for other friendly bacteria to thrive. Prevents overgrowth of pathogenic organisms. 7) Produces lactic acid in the form of L- lactic acid only. The last point is especially important. Lactic acid occurs in the form of three isomers (substances with identical molecular structures that have different shapes): L-lactic acid, D-lactic acid and DL-lactic acid. The D form is metabolized slowly, and can produce acidosis in the system. (Infants have a particularly difficult time metabolizing D-lactic acid.)11,13 DL-Lactic acid, the kind acidophilus makes, may be converted to either D or L. The L form is the one we want. L. sporogenes is a "homofermenter," it makes L-lactic acid exclusively. Lactic acid keeps the gut mildly acidic. This acidity is essential for the gut to be a hospitable home for friendly bacteria, and stops the growth of the unwelcome disease-causing bacteria. L. sporogenes has only one drawback. It is a transient visitor that does not permanently colonize in the digestive tract. A study on the retention of L. sporogenes found no bacteria in the feces six days after consumption was discontinued.14 L. Sporogenes-Results from Clinical Studies L. Sporogenes is used extensively in Japan and approved by the Japanese equivalent of the FDA. L. sporogenes has been given to hospital patients suffering from intestinal complaints such as gas and bloating due to abnormal fermentation, constipation, diarrhea and indigestion. (These problems often occur after surgery or chemotherapy.) A total of 16 clinical reports are on record in Japanese hospitals, documenting 293 case of digestive complaints treated with L. sporogenes.15 The overall improvement rate is an impressive 86 percent. Results are typically seen within four to five days. L. sporogenes has also been used with success to clear up diarrhea in newborns.16 Like other lactobacilli, L. sporogenes lowers blood cholesterol. (Lactobacilli break down cholesterol and bile salts in the intestinal tract.) Researchers at a hospital in New Delhi, India gave L. sporogenes tablets to 20 patients with high cholesterol for twelve weeks.17 Total cholesterol levels were substantially reduced, along with LDL cholesterol, and the beneficial HDL rose slightly. The popularity of L. sporogenes in other countries as an ideal friendly bacteria supplement will no doubt be soon matched in the U.S. This microscopic helper for intestinal health is now sold in probiotic products under the name "Lactospore®." References 1. Gandhi, A.B., Nagarathnam, T. Probiotics in veterinary use. Poultry Guide 1990;27(3):43-47. 2. Brennan, M., Wanismail, B., Ray, B. Prevalence of viable Lactobacillus acidophilus in dried commercial products. Journal of Food Protection 1983;46(10):887-92. 3. Gilliland, S.E., Speck, M.L. Enumeration and identity of lactobacilli in dietary products. Journal of Food Protection 1977;40(11):760-62. 4. Dalton, R.H. The limit of human Life, and how to live long. JAMA 1893;20:599-600. 5. Shahani, K.M., Ayebo, A.D. Role of dietary lactobacilli in gastrointestinal microecology. American Journal of Clinical Nutrition 1980;33:2448-57. 6. Metchnikoff, E.. Prolongation of Life. New York: G.P. Putnam Sons;1908. 7. Donaldson, R.M. Normal Bacterial populations of the intestine and their relation to intestinal function. New Eng. J. Med. 1964;270(18):938-45. 8. Jensen, B. Tissue Cleansing Through Bowel Management. Escondido, CA: publ. by Bernard Jensen, D.C.;1980. 9. Schauss, A.G. Lactobacillus acidophilus: method of action, clinical application, and toxicity data. Journal of Advancement in Medicine 1990;3(3):163-78. 10. 'General InformationÐLactospore®' 1996; Sabinsa Corporation: Piscataway, NJ. 11. Gandhi, A.B. Lactobacillus sporogenes, An Advancement in Lactobacillus Therapy. The Eastern Pharmacist August 1998:41-44. 12. Kim, Y.M., Lee, J.C., Choi, Y.J., Yang, H.C. Studies on the production of beta galactosidase by lactobacillus sporogenes. Properties and application of beta galactosidase. Korean J. Appl. Microbiol. Bioeng. 1985;13(4):355-60. 13. Oh, MS. D-Lactic acidosis in a man with short bowel syndrome. New Eng J Med 1979;31(5):249-52. 14. Hashimo, K. et. al. New Drugs and Clinics 1964;13(9):53-66. 15. 'Abstracts of papers on the clinical studies of Lacbon' Unpublished data. 16. Dhongade, R.K., Anjaneyule, R. Lactobacillus sporogenes (Sporlac) in neonatal diarrhea. Unpublished data. 17. Mohan, J.C., Arora, R., Khaliullah, M. Preliminary observations on effect of Lactobacillus sporogenes on serum lipid levels in hypercholesterolemic patients. Indian J. Med. Res. 1990;92(B):431-32.
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For women of all ages, hormone balance is crucial for overall health and well-being. Unfortunately, many women experience problems with hormone balance at some point in their lives. This can be due to a variety of factors, including stress, diet, and environmental toxins. Fortunately, there is a supplement that can help support healthy hormone detoxification and liver function: DIM complex. Here we will discuss the benefits of DIM complex for women of all ages and how it can help you achieve optimal health! 
Morning Sugar Crave!
Essential amino acids are amino acids that cannot be synthesized by the body and must be ingested from plant and animal sources. There are ten essential amino acids needed by humans plus an extra two essential amino acids needed by infants. For athletes, a large amount of essential amino acids of all types is needed to help repair, grow and maintain muscle. This iis where 3 essential amino acids come into play .These are leucine, isoleucine and valine.
Pantethine (bis-pantethine or co-chemical pantethine) is a dimeric type of pantothenic harsh corrosive (vitamin B5). It is made out of two particles of pantothenic harsh corrosive connected by cysteamine crossing over aggregations. The monomer of this compound is regarded as pantetheine and is a halfway in the generation of Coenzyme A by the form. Pantethine is acknowledged the all the more naturally animated type of vitamin B5, yet it is less stable, disintegrating over the long haul in the event that it is not kept refrigerated most vitamins B5 supplements are subsequently as calcium pantothenate, a salt of pantothenic harsh corrosive. 
First of all what is Creatine? Creatine is a protein that is produced by the human body and converted to creatine phosphate and stored in muscles. The stored form can then be utilized for energy by the muscles. It is also found in meat and protein rich food products such as fish. Some clinical studies have surmised that creatine as an oral supplement enhance muscle strength and increase lean muscle bulk. 
Milk thistle has been used to treat liver problems for centuries. Its Latin name is Silybum marianum which explains the name of its main flavanoid complex, silymarin, which is obtained from the seeds. Milk thistle offers both a regenerative and a boosting effect to the liver, improving its effect on toxins while enabling it to recover from damage caused by cirrhosis, hepatitis and the effect of toxins and drugs. 
So if you take acetaminophen or drink alcohol on a regular basis, or you just want to protect your liver, what is stopping you from taking milk thistle? 
Comments by Craig Gerbore, CEO of Madhava: 
Who is the author, Rami Nagel? 
DHEA is a naturally occurring hormone that is produced within the adrenal glands. The most abundant hormone found in the body, it is sometimes referred to as the “mother hormone.” When hormone levels are too low or out of sync, the body is unable to function as intended. DHEA levels reach their peak in the body around age twenty-one. After that, the levels tend to decline over the years. This substance is a precursor hormone that can be metabolized into other adrenal hormones and act with other hormones. 
