Genus Rubiaceae

Common Names

Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.

Parts Used

The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.

Physical Description

Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.

Chemical Constituents

Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.

FLOWER

FRUIT

discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.

ROOT AND ROOT BARK

Pharmacology

Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.

Body Systems Targeted

The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.

Satety

Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.

Suggested Uses

Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .

NONI: ITS USE AND HISTORY

Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .

Wonder Herb of Island Folk Healers

Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.

Noni’s Medical Reputation

Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.

A Timely Reemer gence

Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.

TRADITIONAL USES OF NONI

Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15

decoctions to stimulate delayed menst ruation.

XERONINE: THE SECRET OF NONI?

One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .

Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18

NONI PROCESSING

How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.

MODERN APPLICATIONS OF NONI

Overview

Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.

Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.

xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.

Cancer

A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21

In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.

Arthritis

with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.

Immune System

The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.

The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.

Antioxidant

The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.

Diabetes

While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.

Pain Killer

A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29

Skin Healing Agent

One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.

burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30

Drug Addiction

The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.

Complementary Agents of Noni

PrimaryApplications of Noni

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=570)

Date: June 14, 2005 10:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nutritional Scorecard

Nutritional Scorecard by Sylvia Whitefeather Energy Times, June 15, 2004

For over 50 years, the federal government has produced Recommended Daily Allowances (RDAs) as guidelines for vitamin and mineral intake. Then, in 1993, the Reference Daily Intakes (RDIs) superseded the RDAs. By applying this new designation, the government's guidelines are now supposed to represent the designated amounts that an average person should consume. With this in mind, and the fact that many experts think you should consume more than some of the RDIs, how does your nutritional scorecard add up? Answering a few nutritional questions can point you in the right direction.

Perfect Protein

Are you trying to lose weight? If you are, the latest thinking on weight loss opines that eating more protein may be the key to keeping your weight down. Two recent studies published in the Annals of Internal Medicine (5/18/04) found that people who ate a low-carbohydrate, high-protein diet lost more weight and had better cholesterol levels than dieters who ate fewer fatty foods. Both studies found that a low-carb diet can improve your triglycerides (blood fats) and boost your HDL, or good, cholesterol.

Eating protein satisfies both tummies and taste buds. Researchers have found that the amount of protein eaten in a meal determines not only how much food you eat but also how satisfied you feel after eating (J Nutr 2004 Apr; 134(4):974S-9S). And when you feel satisfied after eating less food you improve your odds of losing weight.

We need about 50 grams of protein a day to support the body's functions. The best sources of protein are eggs, meat, milk, protein shakes and yogurt.

Classy Carbohydrates

Does your energy level go up and down during the day? To get off the energy rollercoaster, cut down on carbohydrates, and make sure the carbs you do eat are complex.

Carbohydrates have been getting some unflattering press lately. Yes, if you want to lose weight, you may want to go on a strictly low-carb diet. But for those not concerned with weight, carbohydrates are the principle source of energy for the body.

What's more, even if you do restrict carbohydrates, you should still eat a tiny bit of them. Without some carbs in the diet your body cannot regulate protein or fat metabolism. According to Michael and Mary Eades, MD, authors of The 30-Day Low-Carb Diet Solution (Wiley), "Carbohydrates control insulin and insulin controls your metabolic health."

So, make your carbohydrates count. Indulge in complex carbohydrates: whole grains, fruits and vegetables. In those foods, carbs are accompanied by fiber and larger amounts of vitamins and phytonutrients. Other reliable sources of complex carbohydrates are whole wheat bread, brown rice and oatmeal.

Fabulous Fiber

Are you concerned about your heart health? Fiber from beans, oats, legumes, nuts, rice bran, fruits and vegetables helps stabilize blood sugar and reduce cholesterol. Pectins, found in apples, pears, prunes and plums, are a particularly useful form of water-soluble fiber.

Insoluble fiber, in cereals, wheat bran and vegetables, reduces the risk of colon-related problems. In addition to adding fiber to the diet, dried beans and soybeans have been shown to lower cholesterol, improve vascular health and kidney functioning, preserve bone mineral density and reduce menopausal discomforts (AJCN 1999 Sept; 70(3 suppl):464S-74S). Fiber also promotes good bowel health and encourages the growth of beneficial intestinal flora.

You need 25 to 40 grams of fiber daily. If you have cut back on your carbohydrates, be sure to take a reliable fiber supplement.

Fantastic Fats

Do you have problems focusing on mentally challenging tasks? If so, you should eat more fish and get more of the omega-3 fatty acids that fish and flax contain. Higher levels of this type of fat have been linked to better concentration while performing demanding intellectual work (Lipids 2004 Feb; 39(2):117-23).

Fats add flavor to food, making meals taste better. Monounsaturated fats like plain olive oil and canola are liquid at room temperature and are suitable for use in cooking at high temperatures. Researchers have found that a diet high in monounsaturated fat has the ability to decrease LDL (bad) cholesterol (J Nutr 2001; 131:1758-63). Other fats, such as extra virgin olive oil and flaxseed oil, are best used in dishes that don't need cooking, such as salads.

Although the RDI for fat is less than 30% of the total calorie intake, some researchers believe that if you eat healthy fat, eating too much is not a concern. Omega-3 fats are available in supplement form.

Wonderful Water

Do you suffer from dry skin? You may not be drinking enough water. This precious liquid is used by every cell of our bodies and makes up 60% to 75% of our body weight. Water is important for kidney function. Researchers in Italy found that drinking adequate amounts of water can help prevent the formation of kidney stones (Urol Int 2004; 72 Suppl 1:29-33).

Your activity level, environment and diet influence how much water you need daily. Try to drink at least eight cups of fluid a day from noncaffeinated, nonalcoholic sources.

Voluptuous Vitamins

Do you exercise frequently? If you do, you need more antioxidant vitamins like natural vitamin E and vitamin C as well as a healthy supply of carotenoids. A study at the School of Applied Medical Sciences and Sports Studies, University of Ulster, found that exercisers need more antioxidants. Otherwise, their exertion may release an excess number of free radicals (caustic molecules) in their bodies and do damage to the heart arteries and other internal organs.

Vitamins, in general, are defined as micronutrients that are necessary for life. They are necessary for the production of energy, a healthy immune system and hundreds of other functions in the body.

Vitamins aren't the only substances that produce big benefits in small quantities. Phytonutrients are chemicals in plants that have health-promoting properties. These nutrients are getting more and more attention from researchers who are keeping score on our nutritional requirements.

Mineral Crunch

Do your meals contain plenty of calcium? If not, you may need supplements to keep your bones strong and help keep your weight down. One study, presented at the Experimental Biology 2003 meeting in San Diego, found that young women who consumed more calcium had better luck controlling their weight. In this research, it didn't take much calcium to make a difference in waistlines. Consuming just one more serving daily (a cup of milk or a thumb-sized piece of cheese, each of which contain about 300 mg of calcium) made, on average, about a two-pound difference.

In addition, many experts recommend multimineral supplements (along with multivitamins) to promote better health. A recent study of people with immune problems, for instance, found that those kinds of supplements seem to help boost the immune system (AT News 2004 Feb 27; 398:4-5).

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=342)

Date: June 13, 2005 07:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Say Goodbye to Headaches

Say Goodbye to Headaches by Susan Weiner Energy Times, December 8, 1999

What's in a name? A headache by any other name hurts just as much. But categorizing your headache can be as overwhelming as finding an obscure breakfast cereal at the supermarket. Medical folks pigeonhole headaches as tension headaches, allergy headaches, morning headaches and sinus headaches, plus the organic, migraine, cluster, trauma, TMJ, eyestrain, rebound, exertion, hormonal and muscle tension varieties. You may also suffer the self-induced hangover and toxicity headaches.

Americans are no strangers to self-medication, and as a society we battle these headaches by consuming nearly 80 billion tablets of aspirin each year, about 20 million aspirins a day, according to Burton Goldberg, co-author of An Alternative Medicine Definitive Guide to Headaches (Future Medicine Publishing). And while we drown ourselves in over-the-counter and powerful prescription products, our tolerance, just like a drug addict's, grows. So what begins as a twodose headache slowly evolves into three, four or five doses, until you realize that no dosage can make your headache go away.

Unless you're fond of medieval practices such as ritualistic healings and bloodletting, drugs seem the only answer to headache misery. But even modern medicine has been unable to solve headaches. Rather than a cure, medications provide only temporary relief, and even that isn't guaranteed. Additionally, over-reliance on medications can lead to chronic head pain. According to Goldberg, rebound headaches often result from the consumption and withdrawal of drugs.

Halt Your Headaches

Rather than strive to simply eliminate headache pain, why not identify the underlying cause and prevent the headache? Almost always, every type of headache results from a health or lifestyle-related activity. In an ideal world, the best approach would be to eliminate the tensions, stress, frustrations, anger, insufficient sleep, excessive drinking and poor diet that contribute to your headaches. For better or for worse, however, you can't always: a. quit your job; b. ask your spouse to leave; c. sit on the beach all day; or d. all of the above. But you can make appropriate lifestyle changes and learn to express suppressed feelings.

This approach, lifestyle modification, is a treatment program based on a Loma Linda University study, originally published in Medical Hypothesis and the Journal of Women's Health and Gender-Based Medicine and later explained in No More Headaches, No More Migraines: A Proven Approach to Preventing Headaches and Migraines by Zuzana Bic, DrPH and L. Francis Bic, PhD (Avery). The program, conducted on a group diagnosed with chronic migraines, dramatically decreased the frequency, intensity and duration of headaches in nine of 10 headache sufferers. Rather than demand radical life changes, the lifestyle modification program introduces gradual changes in three specific areas: nutrition, exercise and understanding stress. The study doesn't expect you to change your entire diet, join a gym and eliminate everything that triggers stress, but teaches techniques to make subtle lifestyle changes and reduce the impact of daily stress. These same techniques can also improve sleep patterns, a factor known to affect headaches. The lifestyle modification approach clarifies that while very few headaches directly result from existing acute conditions, recurring headaches often derive from a larger lifestyle factor. If these issues are ignored, the body's natural defense mechanisms may kick into overdrive and become exhausted, leaving you susceptible to other chronic diseases. By finding and eliminating the cause of your headaches, you may be saving yourself from other eventual illnesses.

Natural Alternatives

Willing to make some lifestyle changes and step away from medications? Try these remedies, courtesy of Nature's Pharmacy by Lynn Paige Walker, PharmD and Ellen Hodgson Brown, JD (Prentice-Hall).

For simple headaches, start with relaxation and neck stretches. Or try rubbing your forehead with peppermint oil, a natural antispasmodic and diuretic shown in German research to be as effective as acetaminophen in easing tension headaches.

Never underestimate the old-fashioned ice pack to the forehead as an effective treatment that works by constricting the swollen blood vessels that cause your head to ache. If the ice pack isn't enough, try putting your arms in icy water up to your elbows to constrict additional blood vessels. But if it's a sinus headache you're fighting, take the opposite approach and try hot compresses.

The herbal, and original, form of aspirin is white willow bark. Used by Chinese practitioners 2,500 years ago, it contains salicin, nearly the same pain reliever found in aspirin. Other herbal aspirins include meadowsweet tea, just as effective as aspirin with few side effects. For migraines, Walker and Brown recommend feverfew and magnesium supplements, which reduce nerve excitability and migraine susceptibility. In fact, individuals with frequent headaches have been found to have low brain and tissue magnesium, says Julian Whitaker, MD, author of Julian Whitaker's Guide to Natural Healing (Prima). For all headaches, Goldberg suggests essential fatty acid supplementation with evening primrose oil (EPO), which improves circulation, helps regulate inflammation and relieves pain.

The Curse of the Migraine

Migraines, a debilitating headache distinguished by a throbbing pain, may be humanity's oldest malady. The name is derived from the word the Greek physician Galen used to describe the disorder in 200 A.D. Six-thousand-year-old Sumerian writings refer to the ravages of migraines, and prehistoric skeletons bear testimony to a crude form of trephination-holes chiseled in skulls to allow the escape of pain-creating demons, according to Lifetime Encyclopedia of Natural Remedies by Myra Cameron (Parker Publishing).

In the common migraine, throbbing pain develops gradually from distended veins around the brain and may be accompanied by nausea, vomiting and sensitivity to light. These miseries can be preceded by 15 to 90 minutes of an "aura," which includes visual disturbances, distorted perception, hallucinations, flashes of light and temporary loss of sight or hearing. In fact, skeptical historians attribute some of the religious visions of the Middle Ages to the visual effects of migraine aura, according to Cameron.

Snacking on high fiber foods between three light meals each day helps stabilize blood sugar and prevent migraines. And while some doctors summarily attribute migraines to diet, other experts attribute at least half of all migraines to food sensitivities. The most common edible villains are aged cheeses, yeast breads, chocolate, cured meats, citrus fruits, eggs, fermented foods, wheat, milk, milk products, alcoholic drinks and food additives, including nitrates and MSG.

Suggested daily supplements for migraine-susceptible individuals include a multivitamin, one capsule of B complex to help maintain normal vascular control, 3,000 to 6,000 milligrams in divided doses of vitamin C with bioflavonoids to assist the production of anti-stress hormones, and 500 to 1,000 milligrams of magnesium to reduce nerve excitability and pain. At the onset of a migraine, says Cameron, try homeopathic remedies, dilutions of natural substances from plants, minerals and animals. For throbbing pain, take natrum muriaticum according to package directions. Other homeopathic options to explore include iris versicolar, lac defloratum and sanguinaria.

Take Charge of Your Headaches

Headache management involves managing your life. Practice relaxation techniques to reduce stress. Calmly discuss your feelings. Take a leisurely stroll at lunch. Walk your dog, or a neighbor's dog, after dinner. Keep a food diary. Sit and stand tall. Skip the fast food tonight. Join a yoga class. Take vitamins and supplements. Get a two-hour massage. Turn the television off earlier and sleep in a little later.

Taking the time to care may take effort, but it will soon become second nature. Invest in yourself. It's your most precious possession.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=332)

Date: June 10, 2005 10:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Battle Fatigue! Don't passively accept chronic exhaustion and weakness.

Battle Fatigue! Don't passively accept chronic exhaustion and weakness. by Joanne Gallo Energy Times, December 6, 1999

Most folks wouldn't seek the distressing distinction of suffering chronic fatigue syndrome. Aside from a dizzying array of discomforts associated with the malady, the lack of a definitive cause, and few remedies offered by the medical establishment, scornful skeptics lob accusations of laziness or boredom or just plain moodiness. "Snap out of it!" they say, with little sympathy or understanding. "Just get moving!"

But if you're one of more than 3 million Americans affected by chronic fatigue, you know your problem is not all in your head. Your symptoms are real and they extend far beyond mere tiredness. In addition to a debilitating sense of fatigue that can make everyday existence feel like an overwhelming struggle, you may suffer from impaired concentration and memory, recurrent sore throats, nagging headaches, muscle and joint pain, swollen lymph nodes and fitful sleep. The persistence of any one of these effects alone could be debilitating, but the overall diminished capabilities of the chronic fatigue sufferer can become the most discouraging aspect of the disease.

But before you give up hope on kicking this energy-sucking ailment, look to natural ways to boost your immune system and regain your stamina for a more healthy and productive life. New research points to powerful, energy enhancing supplements which, combined with a nutritious diet and stress reducing techniques, can help you reclaim your body from a swamp of sluggishness.

Yuppie Flu?

Part of the public's misconceptions about chronic fatigue syndrome (CFS) may stem from vague definitions of exactly what it is and its causes.

In the '80s, CFS was often mentioned in the same breath as the Epstein-Barr virus, which garnered much notoriety as the "yuppie flu": a state of chronic exhaustion that often plagued young, overworked professionals, as the media trumpeted. CFS was initially thought to be the result of the Epstein-Barr virus, and the two were often considered to be the same thing. Since the Epstein-Barr virus causes mononucleosis, the term "chronic mono" was also thrown around to refer to long-lasting states of fatigue.

Today, CFS is defined as a separate disorder from the Epstein-Barr syndrome. Researchers have found that CFS is not caused exclusively by the Epstein-Barr virus or any other single infectious disease agent. According to the Centers for Disease Control (CDC) in Atlanta, CFS may have multiple causes, in which viruses or other infectious agents might have a contributory role. Some of these additional possible culprits include herpes simplex viruses, candida albicans (yeast organisms), or parasites.

According to the CDC, a person can be definitively diagnosed with CFS when she or he experiences severe chronic fatigue for six months or longer that is not caused by other medical conditions, and must have four or more of the following problems recurrently for six consecutive months: tender lymph nodes, muscle pain, multi-joint pain without swelling or redness, substantial impairment in short-term memory or concentration; sore throat, headaches, unrefreshing sleep and postexertional malaise lasting more than 24 hours.

Even if you are not diagnosed with CFS, you could still probably use some help in fending off fatigue. You may suffer from another poorly understood condition like fibromyalgia, which causes similar symptoms of exhaustion and pain with additional stomach discomfort. You may cope with another ailment like hypoglycemia or low thyroid function that zaps your energy. Or you could be like almost every stressed-out American adult trying to do it all at the expense of your well-being. Though researchers still search for a definitive cause for CFS, one thing is certain: Constant stress and poor nutritional habits weaken the immune system's ability to ward off a host of debilitating viruses and organisms. So before you run yourself down and succumb to a chronic condition, learn how you can build up your defenses now.

Nutrient News

Some of the most exciting new research in CFS treatments focuses on NADH or Coenzyme 1, an energy-enhancing nutritional supplement. This naturally-occurring substance is present in all living cells including food, although cooking destroys most of it. Coenzymes help enzymes convert food and water into energy and NADH helps provide cellular fuel for energy production. It also plays a key role in cell regulation and DNA repair, acts as a potent antioxidant, and can reportedly improve mental focus and concentration by stimulating cellular production of the neurotransmitters dopamine, noradrenaline and serotonin.

A recent study conducted at Georgetown University Medical Center in Washington, DC, and reported in the February 1999 issue of The Annals of Allergy, Asthma & Immunology, showed that chronic fatigue sufferers improved their condition significantly by taking Enada, the stabilized, absorbable, oral form of NADH. The researchers found that 31% of those who took the supplement achieved significant improvement in relief of their symptoms, and a follow up study showed that 72% achieved positive results over a longer period of time.

Coenzyme-A and Coenzyme Q-10 (Co-Q10) are related coenzymes also necessary for energy production.

According to Erika Schwartz, M.D., and Carol Colman, authors of Natural Energy: From Tired to Terrific in 10 Days (G.P. Putnam's Sons) CoQ10 in combination with the nutrient carnitine enhances cellular energy production, thereby boosting energy levels. Coenzyme-A is required to initiate the chemical reactions that involve the utilization of CoQ10 and NADH for the production of energy at the cellular level.

Another important energy-enhancing nutrient is D-ribose, a simple sugar that is crucial to many processes in your body. D-ribose stimulates the body's production of adenosine triphosphate, or ATP, an energy-rich chemical compound that provides the fuel for all body functions. D-ribose is essential to the manufacture of ATP and maintaining high levels of energy in the heart and skeletal muscles.

Vitamin Power

In addition to these new nutrients, a host of more familiar vitamins and minerals can help banish fatigue. According to Susan M. Lark, M.D., author of the Chronic Fatigue Self Help Book (Celestial Arts) nutritional supplements help stimulate your immune system, glands and digestive tract, promote proper circulation of blood and oxygen, and provide a calming effect. Some of Lark's recommended nutrients for building and regaining strength include:

Vitamin A: Helps protect the body against invasion by viruses that could trigger CFS, as well as bacteria, fungi and allergies. Supports the production and maintenance of healthy skin and mucous membranes, the body's first line of defense against invaders. Also supports the immune system by boosting T-cell activity and contributing to the health of the thymus, the immune-regulating gland.

Vitamin B Complex: Depression and fatigue can result from the body's depletion of B vitamins, which can occur from stress or drinking too many caffeinated beverages. Studies have provided preliminary evidence that CFS patients have reduced functional B vitamin status (J R Soc Med 92 [4], Apr. 1999: 183-5). The 11 factors of B complex are crucial to glucose metabolism, stabilization of brain chemistry and inactivation of estrogen, which regulate the body's levels of energy and vitality. n Vitamin C: Helps prevent fatigue linked to infections by stimulating the production of interferon, a chemical that can limit the spread of viruses. Helps fight bacterial and fungal infections by maintaining healthy antibody production and white blood cells. Also necessary for production of adrenal gland hormones which help prevent exhaustion in those under stress.

Bioflavonoids: Help guard against fatigue caused by allergic reactions; their anti-inflammatory properties prevent the production of histamine and leukotrienes that promote inflammation. Bioflavonoids like quercetin are powerfully antiviral.

Vitamin E: Has a significant immune stimulation effect and, at high levels, can enhance immune antibody response.

Zinc: Immune stimulant; improves muscle strength and endurance. Constituent of many enzymes involved in metabolism and digestion. n Magnesium and Malic Acid: Important for the production of ATP, the body's energy source. Magnesium is also important for women who may develop a deficiency from chronic yeast infections.

Potassium: Enhances energy and vitality; deficiency leads to fatigue and muscle weakness.

Calcium: Combats stress, nervous tension and anxiety.

Iodine: Necessary to prevent fatigue caused by low thyroid function, as it is crucial for the production of the thyroid hormone thyroxin.

Herbal Helpers

In addition to nutrients to bolster your immunity, herbal remedies can also help suppress viral and candida infections. Garlic is a powerful, natural antibiotic, while echinacea and goldenseal have strong anti-infective abilities. Other botanicals help combat tiredness and depression: stimulating herbs such as ginger, ginkgo biloba, licorice root and Siberian ginseng can improve vitality and energy. For anxiety, moodiness and insomnia try passionflower or valerian root, which both have a calming effect on the central nervous system.

Eating For Energy

Supplements can only do their best if you eat a nutritious diet. Start by cutting out large quantities of sugar, caffeine, alcohol, dairy products, red meat and fat.

But what are the best foods when trying to restore energy or recover from illness? "High nutrient content foods with a good balance of proteins and carbohydrates," answers Jennifer Brett, ND, interim clinic director and chair of botanical medicine at the University of Bridgeport College of Naturopathic Medicine.

"You want foods with high nutritional value-that's where vegetables end up looking better than fruit."

Brett enthusiastically pushes that "universal food," as she calls it: chicken soup.

"In China," she says, laughing, "they do make chicken soup, and they do think of it as healing, because they add astragalus and shiitake mushrooms. Vegetable soups with chicken or fish have high nutritional value and are easy to digest."

The same principle applies to juices, Brett says. Juices are a good way to tastefully get more phytonutrients from fruits and vegetables into your diet. Toss in protein powder, and you can make a complete meal in your blender.

"You get more energy from juicing," she explains, "more accessible nutrients and carbohydrates that are not bound up in fiber." Brett's additional recommendation: oatmeal.

"It's got protein and carbohydrates combined with a lot of minerals, which you may not get from a sugary cereal," she says. "Sure, they spray some vitamins on them, but if you don't drink the milk in the bottom of the bowl, you'll miss out on them. You might as well take a multivitamin."

Fabulous Fiber

Look to fiber for superior energy enhancement. Natural Energy author Schwartz calls it downright "miraculous": "In terms of conserving precious energy, fiber-rich foods are your cells' best friends," she writes. "It takes smaller quantities of them to give you a full, satisfied feeling. They release all their benefits slowly, which allows the cells to extract nutrients with much less effort. Then these fiber-rich foods graciously leave the body with ease and efficiency." Among these "slow burn" foods that Schwartz says raise blood sugar slowly and steadily and maintain energy evenly:

Alfalfa sprouts-high in fiber and low in cholesterol.

Apples-one medium unpeeled provides 10% of the recommended daily fiber dose; unlike sweeter fruits, which are rich in healthful fiber, they help regulate blood sugar.

Broccoli-along with such greens as cauliflower, cabbage, kale, collard greens and broccoli rabe, it's packed with fiber, vitamins and minerals n Brown rice, wild rice, other whole grains-fiber treasure troves, including barley, quinoa, millet and buckwheat.

Corn-excellent fiber source.

Lentils and other legumes-high in fiber, delicious beans are rich in culinary possibilities.

Oat bran and wheat bran-mix into yogurt or add to cereal for the best available access to fiber.

Popcorn-an excellent snack.

Citrus for More Energy

If constant colds and infections are draining your energy, healthy helpings of citrus fruit may be the pickup you need. According to Robert Heinerman, in Heinerman's Encyclopedia of Healing Juices (Parker), citrus fruit have been used for more than a thousand years as natural remedies for a wide variety of ailments:

Kumquat juice is supposed to help clear up bronchitis. Lemon juice with a pinch of table salt eases a sore throat. Lime juice in warm water soothes aches and cramps from the flu. Tangerine juice can break up mucous congestion in the lungs. Along with citrus' vitamin C, these fruits also supply carotenoids, antioxidants that provide disease-preventing benefits. Citrus also often contain calcium, potassium, folate (a B vitamin that fights against heart disease), iron and fiber.

Fruits are loaded with phytochemicals, naturally occurring chemicals that give fruit their vibrant colors. Yellow, red and orange fruits are also high in flavonoids, like quercetin, a substance which fights cancer. Quercetin also aids in prevention of cataracts and macular degeneration, according to author Stephanie Beling, MD, in her book Power Foods (Harper Collins).

Even the US Department of Agriculture agrees on this flavonoid's benefits, noting in its phytochemical database that quercetin is an "antitumor promoter, antiasthmatic, anticarcinogenic, antiplaque, cancer-preventive, capillariprotective." (Quercetin is also available as a supplement.)

Don't Avoid Avocados

For a vitamin rich food, few items beat the avocado which holds vitamins E and C as well as some B vitamins (B6, niacin, riboflavin). A significant source of beta carotene, though not nearly as much as carrots or sweet potatoes, avocados also contain high amounts of the minerals potassium, magnesium, copper and zinc.

Just 15 grams of avocado delivers about 81 international units of vitamin A as beta carotene. Beta carotene, a carotenoid in fruits and vegetables, is converted to vitamin A in the body. This vitamin, aside from providing antioxidant protection from damaging free radicals, is necessary for good eyesight, healthy skin and healing.

In addition, the avocado, like all of these healthy foods, tastes great. Which means that you can pep up and not have to sacrifice taste for zest.

Healthy Mind, Healthy Body

Remember that the path to wellness begins in your mind. Stress-reducing activities like yoga, meditation and massage and aromatherapy can have a great rejuvenating effect on your body. If you can learn to handle stress effectively instead of letting it control you-and strengthen your system with the right nutrients and diet-you'll find that fatigue can be a sporadic visitor rather than a chronic companion.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=284)

Date: June 03, 2005 05:35 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NutraSpray in Melatonin, Proanthodyn, and St. John's wort

NutraSpray

NUTRASPRAY represents a quantum leap in the evolution of supplementation, an elegant combination of convenience, fast action, bioavailability, and sustained release delivery. Source Naturals has long championed the sublingual delivery system, and our Super Sublingual™ is the latest step in the science of nutrition. A quick spritz of NUTRASPRAY under the tongue delivers thousands of microscopic lipid spheres, each full of nutrients. These lipospheres are readily absorbed and retained by the mucosal tissue of the mouth. Here they release their nutrients quickly, but steadily, into the bloodstream – creating a Super Sublingual, the most bioavailable supplement today.

Nutrient delivery systems include tablets, capsules, softgels, and liquid extracts. Their purpose is to ensure the cells in your body get the nutrients they need from the supplements you take. Sublinguals bypass the digestive system – and its potentially destructive juices – by dissolving under the tongue to be directly absorbed into the bloodstream. Tests show that the NUTRASPRAY liposome sublingual delivery system is more efficient than traditional sublinguals.

The First Timed Release Sublingual

Due to the multi-layered structure of the tiny lipospheres, nutrients are gradually released for extended periods of time, maintaining optimal dosage throughout the day or night. This combined with a faster onset of the active ingredients – usually within 15 minutes – makes NUTRASPRAY the most bioavailable delivery system for nutritional supplements today, and the first truly timed release sublingual.

Unparalleled Convenience

NUTRASPRAY incorporates a simple, non-aerosol spray pump that’s easily carried in purse or pocket. Its modern functional design is a perfect complement to today’s active lifestyle. It’s easy to regulate nutrient amount, because the convenient pump delivers a specific amount of nutrient-rich liposomes with every spray, and each 2 fl. oz. recyclable plastic bottle can deliver 80 full sprays. Stevia is added as an ingredient in each NUTRASPRAY product.

Advanced Research

The lipid micro-encapsulation process is based on years of research in liposomal technology. The result is NUTRASPRAY, a proprietary system to deliver nutrients in the most efficient manner. This sublingual oral spray is a liquid suspension of liposomes, which are nutrients encased in very complex microscopic lipid spheres, 1/50th the diameter of a human hair. A highly purified natural lecithin forms the membrane of these lipid spheres, which are able to move easily through the lipid environment surrounding the capillaries in the mouth. Lipospheres then gradually release their nutrients into bloodstream.

Nutrients That Go To Your Head

The Source Naturals NUTRASPRAY line includes natural supplements that are particularly well-suited to this Super Sublingual delivery system, such as Melatonin, Ginkgo Biloba, Coenzyme Q10, Grape Seed extract, and Kava. That’s because these nutrients need to reach the brain for maximum benefit. Also, they’re usually taken for reasons that the fast-acting quality of NUTRASPRAY satisfies. Another unique reason NUTRASPRAY is so bioavailable is that its nutrients bypass the liver on their first pass through the circulatory system. This ensures the nutrient is available to the brain for maximum potency. Source Naturals NUTRASPRAY MELATONIN delivers 1.5 mg of the finest quality Melatonin with each full spray, easily allowing customers to control their intake. Melatonin is ideally suited to the fast-acting nature of NUTRASPRAY, which maintains a more balanced release of Melatonin throughout the night. Source Naturals NutraSpray GINKGO-24™ provides 60 mg of Ginkgo Biloba per full spray. This makes Ginkgo’s beneficial constituents readily available to the capillaries in the blood-brain barrier, facilitating oxygen flow to the brain. CoQ10 is fat soluble; therefore encapsulating it in a lipid is the perfect way to ensure its bioavailability. Each full spray of Source Naturals NUTRASPRAY™ COQ10 yields 30 mg of CoQ10. Furthermore, this popular metabolic enhancer is very experiential with the NUTRASPRAY delivery system. NUTRASPRAY GRAPE SEED extract delivers 50 mg per spray of proanthocyanidins standardized to 95%. These highly bioavailable flavonoids are able to cross the blood-brain barrier, offering potent antioxidant protection to precious neurons. NUTRASPRAY KAVA KAVA is a potent extract standardized to a potent 40% kavalactones, the active constituents of this traditional root from the Polynesian cultures of the South Pacific. The relaxing action of Kava works through the brain’s limbic system, which regulates emotions related to survival issues, including the “fight or flight” response. Each spray yields 60 mg of Kava. Look for other fine products soon to come out in the Source Naturals line of NUTRASPRAYS. Source Naturals built its reputation on bringing the latest nutritional research to market, using the finest ingredients in substantial quantities – for an experience of wellness and vitality you can feel. Source Naturals NUTRASPRAY is a major step toward empowering people to achieve optimal health in a challenging world.

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VitaNEt ®
VitaNet ® Staff

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=171)

Date: June 02, 2005 12:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

Heart Science 30 tabs

Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
1) generating energy,
2) decreasing harmful homocysteine levels,
3) fighting oxidized cholesterol,
4) maintaining the heart’s electrical rhythm, and
5) protecting artery and capillary linings.

Energy Generators for An Energetic Organ

Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

Homocysteine Regulators

B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

The Dangers of Oxidized LDL Cholesterol

While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

Cholesterol Fighters

Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

The Regulating Trio

Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.

Artery Lining Protectors

Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

Capillary Strengtheners

Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

Heart Smarts

The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

Source Naturals HEART SCIENCE™

The Five Tiered Approach to Heart Health
Six tablets contain:
Vitamins and Minerals %USRDA
Pro-Vit A (Beta Carotene) 45,000 IU 900%
Vit B1 (Thiamine) 50 mg 3333%
Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
Vit B6 (Pyridoxine HCl) 25 mg 1250%
Coenzyme B6 (Pyridoxal-5-Phosphate)
25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
Vit B12 (Cyanocobalamin) 500 mcg 8333%
Folic Acid 800 mcg 200%
Vit C (Magnesium Ascorbate) 1500 mg 2500%
Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
Copper (Sebacate) 750 mcg 37.5%
Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
Potassium (Citrate) 99 mg *
Selenium (L-Selenomethionine) 200 mcg *
Silicon (From 400 mg of Horsetail Extract) 13mg *
* U.S. RDA not established.
Other Ingredients and Herbs
Coenzyme Q10 (Ubiquinone) 60 mg
L-Carnitine (L-Tartrate) 500 mg
Hawthorn Berry Extract 400 mg
Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
L-Proline 500 mg
L-Lysine (HCl) 500 mg
NAG™ (N-Acetyl Glucosamine) 500 mg
Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
Taurine (Magnesium Taurinate) 500 mg
Horsetail Extract (Yielding 31 mg of Silica) 400 mg
Inositol (Hexanicotinate) 50 mg

Reference:
1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.

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Date: June 01, 2005 11:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: COLLOIDALIFE Trace Minerals - The precious Elements of Life...

ColloidalLife

Throughout history, minerals were crucial to the growth and success of civilizations. From the iron spear to the silicon chip, elements of the earth have influenced the fate of nations. Today, we’re beginning to appreciate the importance of minerals to the growth and health of the human body – especially in light of so many new challenges to our health. It’s no surprise then that trace minerals are in great demand; after all, our lives depend on them. Due to denatured soils and the widespread use of agricultural chemicals, food plants now contain fewer essential minerals. These precious elements of health are our real wealth, and like a modern gold rush, the search is on for valuable trace minerals. Unfortunately though, there’s a lot of “fools’ gold” on the market. Source Naturals built its reputation with leading-edge formulas that make a difference you can feel. Now, after very thorough research, we are proud to offer COLLOIDALIFE, the finest and safest complete trace mineral formula available today.

The ColloidaLife Advantage

Minerals – the Foundation of Life

As human beings, we are profoundly connected with our world. The elements of this earth become the minerals essential to every cell in the body. The millions of chemical reactions occurring within us each second – as molecules are continually broken down and rebuilt into necessary forms – cannot take place without enzymes; and enzymes can’t work unless they’re activated by the right mineral or vitamin. For example, magnesium is the activator mineral for over 300 different metabolic enzymes that facilitate the biochemical processes of life. Most of us are familiar with the minerals that are found in significant quantities in our bodies. We’re aware of the importance of calcium, magnesium, and potassium. There are, however, other minerals that we need in minute quantities called “trace minerals.” Though less understood, research is revealing the vital role they have in the overall structure and function of the human body. Many people are recognizing the need to supplement their diets with trace minerals such as copper, zinc, chromium, manganese, molybdenum, iodine, selenium, silver, and boron.

Modern Agriculture and Mineral Deficiencies

Minerals cannot be produced by the human body and therefore must be obtained from the diet. However, intense agriculture has depleted the soil of most essential minerals, returning only a few used in fertilizers to stimulate rapid plant growth: nitrogen, phosphorus, and potassium. Consequently few people get anywhere near a hundred percent of the RDA (Recommended Daily Allowances) of minerals (and these RDAs are only the minimum amount needed to avoid a full-blown deficiency condition).

A Superior Solution

The key to formulating colloidal trace mineral supplements is found at the molecular level. Colloids are particles in a solution that are completely dispersed and will not settle out. Many trace mineral products are just water leached through mineral deposits, and contain high levels of undesirable minerals. COLLOIDALIFE is prepared through a proprietary process whereby 20 minerals are individually prepared as colloids. These USP grade minerals are then blended with 52 charged ionic mineral electrolytes derived from highly purified ocean water. This ionic solution strengthens the net surface charge of the colloidal particle, creating a more stable colloid. The trace mineral electrolytes in COLLOIDALIFE are present in extremely small, but optimal quantities that prevent the colloids from precipitating out. Because the ionic matter is easily absorbed and is highly reactive in the body, only trace amounts of the different electrolytes are needed. COLLOIDALIFE therefore provides protection from possible deficiencies while avoiding the possibility of toxicity.

Safety First

Some trace mineral formulas have multi-gram per liter levels of aluminum, iron, or sulfur – much higher than desirable – as well as high amounts of arsenic, cadmium, lead, and mercury. (Although a high level of iron produces an energy rush, in the long run it may promote excessive free radicals.) Because COLLOIDALIFE’s mineral colloids are individually prepared, their quantities are specifically controlled. COLLOIDALIFE contains safe levels of the minerals that should be limited in the diet, unlike simple solutions of earth and water. The ocean water containing the ionic minerals is purified by several procedures that remove any environmental or biological contaminants.

The Ocean Within

The minerals in COLLOIDALIFE emulate the way minerals are carried in the blood and used by the cells: colloidal particles suspended in ionic fluid. Sea water – except for its higher salt content – has a mineral profile very compatible to that of the body’s three fluid systems: blood plasma, lymphatic, and extra-cellular. This similarity underscores our intimate connection to the earth and its oceans. Neutral in taste, Source Naturals COLLOIDALIFE can be held under the tongue for sublingual absorption, or swallowed directly. COLLOIDALIFE is the perfect solution to compensate for a mineral-poor diet that may be limiting your ability to enjoy a healthy and vital life.

ColloidaLife – Mineral Profile*

COLLOI D A L MI N E R A L S

PER TSP: PER TSP:
Boron 0.26 mcg Molybdenum 0.075 mcg Calcium 100 mcg Phosphorus 0.279 mcg Chromium 0.012 mcg Potassium 30.75 mcg Copper 0.045 mcg Rhodium 0.035 mcg Iodine 0.035 mcg Selenium 0.002 mcg Iridium 0.002 mcg Silicon 40.5 mcg Iron 0.54 mcg Silver 0.205 mcg Lithium 0.079 mcg Sulfur 12.4 mcg Magnesium 105 mcg Vanadium 0.105 mcg Manganese 1.71 mcg Zinc 33.5 mcg IONIC MI N E R A L S PER TSP: PER TSP : Antimony 0.01 mcg Neodymium 0.0005 mcg Aluminum1 0.42 mcg Nickel 0.014 mcg Arsenic2 0.0004 mcg Niobium 0.001 mcg Barium 0.24 mcg Osmium 0.00002 mcg Beryllium 0.00007 mcg Palladium 0.625 mcg Bismuth 0.0015 mcg Platinum 0.002 mcg Bromine 0.001 mcg Praseodymium 0.002 mcg Cadmium3 0.025 mcg Rhenium 0.0002 mcg Cerium 0.0001 mcg Rubidium 0.007 mcg Cesium 0.1 mcg Ruthenium 0.003 mcg Chlorine 175 mcg Samarium 0.00003 mcg Cobalt 0.0009 mcg Scandium 0.00005 mcg Dysprosium 0.00004 mcg Sodium 1.205 mg Erbium 0.00001 mcg Strontium 0.275 mcg Europium 0.0001 mcg Tantalum 4.2 mcg Fluorine 0.8 mcg Tellurium 0.001 mcg Gadolinium 0.00001 mcg Terbium 0.0001 mcg Gallium 0.005 mcg Thallium 0.0001 mcg Germanium 0.006 mcg Thorium 0.00003 mcg Gold 0.0002 mcg Thulium 0.000005 mcg Hafnium 0.00015 mcg Tin 0.22 mcg Holmium 0.0025 mcg Titanium 0.21 mcg Indium 0.13 mcg Tungsten 0.01 mcg Lanthanum 0.0025 mcg Ytterbium 0.0015 mcg Lead4 0.003 mcg Yttrium 0.015 mcg Lutetium 0.00005 mcg Zirconium 0.0015 mcg

*minute variations may occur among lots.
At 1 teaspoon per day, a 4 ounce bottle of ColloidaLife is a 24 day supply.
1) 0.01% of the daily intake of aluminum in a typical diet
2) 0.0003% of the daily intake of arsenic in a typical diet
3) 0.08% of the daily intake of cadmium in a typical diet
4) 0.002% of the daily intake of lead in a typical diet
Percentages are based on estimated average U.S. daily intake per person.
(Nutritional Biochemistry & Metabolism, edited by Maria C. Linder, 1991)

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Date: June 01, 2005 09:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest

CAT’S CLAW DEFENSE COMPLEX

Standard pharmaceutical drugs came into common use only around the turn of the century. Before that, herbal preparations were administered for health concerns. Today, in nearly every country in the world, herbs are used by health care practitioners as the focal point of health care. Only in the United States is the otherwise widespread use of herbs missing in mainstream culture. But now modern scientific investigation is confirming the benefits of herbal supplementation, which is paving the way for us to reclaim and implement herbs into our everyday lives.

The primary need for preserving the rainforests

Rain Forest Herbs

Scientists’ knowledge of the varied rain forest flora is far from complete. The plants which have been thus far identified are so elaborate in molecular structure that it’s difficult to understand how these molecules function, let alone how to reproduce them. What is known is that the biodiversity of the rain forest yields numerous biologically active plant constituents which can have a profound influence on supporting the body through times of imbalance. Preserving the rain forest means preserving these precious herbs and the unique constituents contained within them.

Cat’s Claw Defense Complex contains powerful rainforest herbs

A Synergistic Blend

Source Naturals CAT’S CLAW DEFENSE COMPLEX harnesses the power of some of the most complex botanicals on earth into a synergistic blend of defense-enhancing herbs, each with a unique set of compounds which complement the body’s natural physiology. Source Naturals CAT’S CLAW DEFENSE COMPLEX is the first step in the rediscovery of a long-standing herbal tradition. Source Naturals was the first full-line supplement company to introduce the herbal superstar, Cat’s Claw, and the first to offer it in a combination formula. CAT’S CLAW DEFENSE COMPLEX provides 2000 mg of Cat’s Claw per four tablets – more than many companies’ single ingredient Cat’s Claw products! It combines powerful rain forest herbs like Pau D’Arco and Western herbs such as Aloe Vera and St. John’s Wort with legendary Chinese herbs (Reishi Mushroom and Astragalus). Source Naturals Cat’s Claw Defense Complex also includes two categories of antioxidants for broad spectrum support.

How we ensure quality and potency

Cat’s Claw & Pau D’Arco – Peruvian Jungle Discoveries

Cat’s Claw was discovered in the depths of the Peruvian Amazon jungle. Researchers have discovered that components extracted from the herb can bolster the body’s innate defenses, address discomforts associated with stress, and support intestinal health. Source Naturals uses only the highest quality Cat’s Claw inner bark – which is at least twenty years old, the amount of time it takes the bark to reach its peak biological activity– and uses a careful process to insure that harvesting the bark doesn’t weaken or destroy the plant. Like all of our herbs, each shipment of Cat’s Claw is also routinely inspected and tested by a trained herbalist to ensure maximum quality and potency. Pau D’Arco is also native to the South American rain forest and, like Cat’s Claw, has a high concentration of active constituents – a combination of anthraquinones and naphthoquinones, primarily lapachol – in the bark of the plant. Each daily dosage of CAT’S CLAW DEFENSE COMPLEX contains 100 mg of Pau D’Arco bark and 100 mg of concentrated Pau D’Arco bark extract for broad spectrum support.

Herbs — Adaptogens for Balance

Of the Chinese herbs, Siberian Ginseng is one of the best known adaptogens. Adaptogens have a balancing effect, helping us adapt to increased stress levels and other changes, like different altitudes or time zones. Thus, supplementation with Siberian Ginseng can help prevent stress-related health concerns. Schizandra, a small creeping vine with red berries, is a Chinese adaptogen which helps regulate the body’s functions and cleanse it of toxins.

Herbs that energize the body and build resistance to impaired bodily function

The trio of Chinese mushrooms – Reishi, Shiitake, and Maitake – has been used by Chinese herbalists for centuries, and provides the highest quality natural support for the body’s defenses. Modern science has revealed the true power behind Reishi, Shiitake, and Maitake: high levels of polysaccharides – long chain sugar macromolecules which are known for their protective and cleansing abilities. CAT’S CLAW DEFENSE COMPLEX utilizes only the mycelia biomass of Reishi (200 mg), Shiitake (200 mg), and Maitake (150 mg) to ensure the highest level of activity. Astragalus is the premier tonic – or internal strengthener – of Chinese herbalism. In addition to helping energize the body, Astragalus also builds resistance to weakness and to impaired bodily function. Isatis is a cooling herb which has been shown to have a broad spectrum inhibitory action in in-vitro studies, and helps support normal liver function. Used for thousands of years, the aloe plant has been treasured for its varied uses both externally and internally. Aloe Vera juice is high in mucopolysaccharides, which have been found to have powerful protective capabilities. CAT’S CLAW DEFENSE COMPLEX provides 200 mg of aloe (200:1 concentration) extracted from the whole leaf of the plant.

Why St. John’s Wort is powerful and useful

It is generally agreed that hypericin and pseudohypericin, two bioflavonoids which are the active constituents in St. John’s Wort, probably act as monoamine oxidase (MAO) inhibitors, which current research has shown are powerful as internal cleansing agents. St. John’s Wort is particularly useful because of its ability to cross the Blood-Brain Barrier, through which many elements are unable to pass.

The liver’s health is essential because of its responsibility for over 500 different functions

Antioxidants and Plantioxidants – Supporting Complete Health

Source Naturals CAT’S CLAW DEFENSE COMPLEX includes key liver-supporting antioxidants like Zinc, Beta Carotene, and Vitamin C – nutrients that help protect the liver from stress and pollution induced free radical damage. These three nutrients are also wellknown for their ability to help strengthen the body’s resistance and move through imbalances quickly. The liver is responsible for over 500 functions, including converting vitamins to their active forms, and processing and eliminating waste products from the body; therefore its health is vital. Plantioxidants™ is Source Naturals’ term for Plant-Derived Antioxidant Bioflavonoids. Though most people are only aware of the vitamin and mineral antioxidants, the latest scientific research has indicated that the plant kingdom may provide the most potent antioxidants in the world. Plants, trees, and citrus fruits all contain bioflavonoids (also called polyphenols) – a large group of restorative compounds with similar chemical structures which help protect the body from the ravages of oxidative damage due to free radicals. Some of the Plantioxidants included in CAT’S CLAW DEFENSE COMPLEX are: Quercetin, which helps inhibit the body’s sensitivity to dangerous particles in the air; Proanthodyn, which promotes tissue repair by helping to strengthen collagen and elastin, the two primary structural components in cartilage; Silymarin, which promotes liver-tissue regeneration and optimizes liver-cell function; Green Tea, a remarkably potent antioxidant; and Ginkgo, which is renowned for helping transport oxygen to the brain.

The way to naturally bolster the body’s defenses

A Holistic Natural Answer

The natural world provides us with a seemingly endless supply of complex herbal compounds with unreplicable and unique constituents so varied and numerous that most doctors aren’t even aware of their existence. Source Naturals would like to change that with CAT’S CLAW DEFENSE COMPLEX – the natural way to bolster the body’s innate defenses. All the ingredients included are at optimal potencies, and in the forms best absorbed by the body. The result? The most powerful, holistic product available to help maintain the structure and function of the natural defenses – Source Naturals CAT’S CLAW DEFENSE COMPLEX.

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