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	How does Vitamins B Complex Work on Skin and Hair?	Darrell Miller	1/17/18
	Why B Vitamins Are the Secret to More Energy - Shape Magazine	Darrell Miller	6/16/17
	Anemia Causes, Prevention And Supplements.	Darrell Miller	8/7/14
	What Is Vitamin B-6 And What Is Its Health Benefits?	Darrell Miller	1/5/14
	Vitamin B-complex can help you to restore adrenal function	Darrell Miller	1/3/14
	Diffrent Health Benefits of Brewers Yeast	Darrell Miller	11/4/13
	VITAMIN B COMPLEX AND ITS HEALTH BENEFITS	Darrell Miller	12/27/12
	vitamin B-6	Darrell Miller	11/17/12
	The Health benefits of P-5-P	Darrell Miller	7/20/12
	What Vitamins And Minerals Are For Mental Alertness?	Darrell Miller	8/29/11
	Can Royal Jelly Really Boost Energy?	Darrell Miller	4/18/11
	Why Should I Be Taking A Vitamin B-Complex?	Darrell Miller	2/3/11
	Beef Liver Is Nutritous For You	Darrell Miller	9/3/10
	Vitamin B Complex	Darrell Miller	11/24/08
	B Vitamin Complex	Darrell Miller	6/23/08
	B Vitamins	Darrell Miller	6/19/08
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	Supplements good for reducing stress and boosting energy!	Darrell Miller	3/26/07
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	Prostate Health Naturally	Darrell Miller	6/16/05
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	Higher Mind - Smart Nutrients for the Performance of a Lifetime...	Darrell Miller	6/2/05
	Heart Science - A Five-Tiered Approach to Heart Health ...	Darrell Miller	6/2/05
	GlucosaMend™ Tissue/Joint Repair Complex	Darrell Miller	6/2/05

Date: January 17, 2018 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How does Vitamins B Complex Work on Skin and Hair?

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Date: June 16, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why B Vitamins Are the Secret to More Energy - Shape Magazine

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Date: August 07, 2014 05:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Anemia Causes, Prevention And Supplements.

What is an anemia?

How to prevent anemia?

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Date: January 05, 2014 09:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Vitamin B-6 And What Is Its Health Benefits?

Introduction

Vitamin B6 is a water soluble vitamin that is part of the vitamin B complex group that consists of pyridoxal (PL), pyridoxine (PN), pyridoxal 5 phosphate, pyridoxine 5 phosphate, 4-pyridoxic acid (PA), pyridoxamine 5 phosphate, and pyridoxamine. pyridoxine is the form that is commonly given as a vitamin B-6 supplement. Vitamin B6 is also found in most multivitamin mineral supplements.

The benefits of vitamin B-6 include:

1. It helps in the formation of red blood cells.
2.  It helps in the maintenance of healthy brain function.
3. It plays a major role in the synthesis of antibodies that are used to fight diseases.
4. It helps in the digestion and breakdown of proteins, hence if you have a high protein intake you need to use vitamin B6 supplements.
5. It helps in the maintenance of normal nerve function and plays a key role in the synthesis of serotonin and dopamine. It also helps in normal communication between nerve cells.
6. Research has shown that vitamin B-6 may help reduce the risk of heart disease by lowering the levels of the amino acid homocysteine.
7. Although scientists have not yet proven the benefits of vitamin B-6 on premenstrual syndrome (PMS) studies have shown that it reduces the symptoms including irritability, bloating, anxiety and moodiness.
8. The American Congress of Obstetricians and Gynecologists recommends the taking of vitamin B-6 supplements under the care of a doctor for vomiting and nausea during pregnancy.

The amount of vitamin B-6 that is needed daily by the body depends on age and sex. Men and women between the ages of 19 and 50 need 1.3mg/day, women who are 51 years and older need 1.5 mg/day, pregnant women need 1.9 mg/day, and men over 51 years need 1.7 mg/day.

Below are some of the foods that contain vitamin B6 (the amount of vitamin B6 they contain is in mg)

Fruits- per carrot juice contains 0.27 mg per 125mls, prune juice contains 0.30mg per 125 mls. and one avocado fruit contains 0.26 mg.

Grains- 30 g of wheat bran contains 0.35 mg of vitamin B6, 30 g of bran contains 0.20 mg

Meats- 75 g of cooked beef liver contain 0.76-0.78 mg, 75g of cooked beef contains 0.14-0.26 mg, 75 g of salmon or tuna contain around 0.67 mg, and other fish (trout, cod, mackerel, snapper, bluefish, and herring contain 0.30-0.39 mg.

Legumes- 0.75 of a cup of soybean contains 0.30 mg, 0.75 of a cup of chickpeas contains 0.84 mg, and 0.75 of a cup of lentils contains 0.26 mg.

The symptoms and signs of vitamin B6 deficiency include:

anemia, depression, convulsion, irritability, morning sickness, and sore tongue.

You can easily meet your daily requirements of vitamin B-6 by taking vitamin B-6 supplements. Athletes who are taking protein and amino supplements should also take vitamin B6 supplements to improve their body’s intake of the proteins and amino acids consumed.

References:

1. //en.wikipedia.org/wiki/Vitamin_B6
2. //asrienne2.hubpages.com/hub/health-benefits-of-vitamin-B6
3. //lpi.oregonstate.edu/infocenter/vitamins/vitaminB6/

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Date: January 03, 2014 05:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin B-complex can help you to restore adrenal function

Adrenalin Gland

We all know that proper functioning of adrenal is highly important for complete health and do not work properly then your body or mind may not function properly. We also know that adrenalin gland create and release a number of required hormones such as adrenaline, cartisol, estrogen, testosterone, and aldosterone that help in normal functioning of body.

What is the Role Vitamin B

This hormone creation process is commonly known as hormone cascade and most of us do not know that Vitamin b-Complex is the most essential material for synthesizing of all these hormones. In this process most of the b-complex vitamins works as coenzymes that means they help the adrenal to form the required hormone by working as catalyst. Other than this, vitamin b-complex helps your body in energy creation and DNA synthesis as well that is essential for proper functioning of adrenal.

If we talk about the role of each vitamin out of all the 8 Vitamin B-complex in proper functioning of adrenal, then we all 8 have some visible effect on it. However, Vitamin B3 also known as niacin, Vitamin B5 or pantothenic acid and Vitamin B6 or pyridoxine are the most important b-complex vitamins that help the adrenal in its acute functioning.

Niacin or vitamin B3 is essential for formation of molecular structure of various co-enzymes and it is required for almost every step of hormone cascade process. Similarly vitamin B5 is also equally important because this particular b-complex vitamin is required for transformation of glucose into energy and it fulfills all the requirement of energy for adrenal hormones. Other than this B6 is another important b-complex vitamin that helps your body to control the adrenal activity and gives proper stress response for proper functioning of your adrenal system. Other than this, other b vitamins work as energy source so if your adrenal is not functioning properly then have complete vitamin B-complex for proper functioning and restoration of your adrenal system.

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Date: November 04, 2013 07:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Diffrent Health Benefits of Brewers Yeast

Health Benefits of Brewer's Yeast

Brewers yeast is not only one of the most important ingredient of beer making but it's a very healthy dietary supplement as well that has so many health benefits as well including controlling of blood sugar, controlling of cholesterol, increment of energy level, nourishment to skin & hair, and it also increase the breast milk supply in women’s.

What is Brewer's Yeast

If we talk about the production of brewers yeast it is a byproduct of beer and it also get developed by a single cell fungus that is popularly known as “Saccharomyces cerevisiae”. Other than this, manufacturers also add a variety of nutritional supplement in it including chromium, vitamins and other minerals that makes it a healthy dietary supplement.

Brewer's Yeast Content

Since, brewers yeast contains a good amount of chromium, vitamin B complex, selenium and protein that makes it a very healthy food. Its B complex contain different Vitamins including B1 or thiamine, B3 that is also known as niacin, B2 also known as riboflavin, B6 known as pyridoxine, B5 or pantothenic acid, B9 known as Folic Acid, and Vitamin H that is also known as Vitamin B7 or biotin.

All these vitamins work effectively on your digestive system and simplify the breaking of fats, carbohydrates and protein that gives a good amount of energy to body. Other than this, it also improves your nervous system and gives strength to muscles of your digestive system for enhancing your digestive system. In addition to this, it also keeps your hair, muscles, skin, mouth, eyes and liver in healthy condition.

Understanding Brewer's Yeast

Although brewers yeast is highly beneficial health supplement but consume also need to understand that this supplement does not contain Vitamin B12 so they need to take it from some other source else they may experience deficiency of Vitamin B12. In addition to this, if consume have any kind of health issue they need to consult with their doctor before taking it to avoid any health problem.

References:

1. //umm.edu/health/medical/altmed/supplement/brewers-yeast
2. //www.webmd.boots.com/vitamins-and-minerals/brewers-yeast
3. //breastfeeding.about.com/od/milksupplyproblems/a/Brewers-Yeast-And-Increasing-Breast-Milk-Supply.htm

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Date: December 27, 2012 11:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: VITAMIN B COMPLEX AND ITS HEALTH BENEFITS

Vitamin B complex is food a supplement that is soluble in water and fundamental in growth, development and cell metabolism. B complex is a group of the B vitamin compounds including thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, B12 (cobalamins), biotin (B7) and folic acid (B9). The distinction of the B complex into numbers arose because initially it was thought to be a single nutrient existing in specific food types only but further research discovered the existence of different compounds in the nutrient. All compounds of the B complex have distinct structures and perform different roles in the body. They play an important role in enzyme activities more so in chemical reactions that lead to production of energy in the body. They are mostly found in plant and animal food sources and also as supplement tablets.

Vitamin B compounds have numerous health benefits each one with a different function.

• Vitamins B1 and B2 aid in the proper functioning of the nerves, muscles and heart. B1 boosts the immune system giving the body strength during times of stress through energy production.
  
• B3 is important in the regulation of the digestive and nervous systems.
  
• Pantothenic acid and cobalamins aid in normal growth and while B7 and folic acid are important in hormone production and DNA maintenance respectively.
  

The different individual health benefits of the compounds are as follows:

• · Prevention of kidney diseases especially in individuals with type 2 diabetes
  
• · Prevention of migraines
  
• · Lowering of body cholesterol levels
  
• · Protection against heart diseases and alleviation of nausea especially during pregnancy
  
• · B9 specifically helps in prevention of different types of cancer such as breast cancer, pancreatic cancer and colorectal cancer and reduction in the risk of occurrence of birth defects in unborn babies
  
• · Research has also show that B12 lowers cervical cancer in women.
  

It is due to these benefits that medical practitioners encourage use of diets rich in vitamin b compounds or intake of the compounds in dietary supplement form as tablets

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Date: November 17, 2012 11:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: vitamin B-6

Vitamin B-6 was discovered by Paul Grorgy in 1930 when doing nutritional studies. He discovered the substance was able to cure a certain skin disease when he tested it in rats. Vitamin B-6 exists in three forms namely pyridoxine, pyridoxamine and pyridoxal. These three are precursors of PLP (pyridoxal 5-phosphate). PLP plays an important role as a cofactor for most enzymes in the body.

Vitamin B-6 has many health benefits.

To begin with, it helps maintain a healthy heart. It prevents the formation of a substance, homocysteine, which damages the lining of blood vessels resulting to the building up of plaque. This happens when the body attempts to repair the damage. It prevents the buildup, reducing chances of a myocardial infarction. It lowers blood pressure, prevents platelet aggregation and it also lowers levels of cholesterol in the body.

Vitamin B-6 from supplements or diets reduces the chances of having Parkinson's disease. In women, it strengthens their immune system and it also promotes proper hormone balance in case of any fluctuations. Vitamin B-6 deficiency exposes one to the carpal tunnel syndrome. It is a disorder that is characterized by a burning or tingling sensation and pain that is felt on the wrist or hand after being strained repetitively. It also causes numbness, loss of strength in hands/ fingers, diminished coordination and swelling. Studies have indicated that increased levels of vitamin B-6, from diets or supplements, reduce symptoms of carpal tunnel syndrome.

Toxic potential in grams per day.

Vitamin B-6 however becomes toxic if taken in excess. It does not relieve the symptoms immediately. Sometimes it takes up to six weeks before noticing any relief. Those suffering from this syndrome should take fifty milligrams of vitamin B-6 twice or thrice daily. You should never take more than two hundred milligrams of vitamin B-6unless you have been recommended to do so by a doctor.

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Date: July 20, 2012 07:51 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Health benefits of P-5-P

P-5-P or Pyridoxal-5-phosphate

P-5-P or the most commonly called Pyridoxal-5-phosphate is known to be the most active form of the Vitamin B6. This is known to be converted from organic compounds pyridoxal, pyridoxine and pyridoxamine. The Vitamin P-5-P is a coenzyme which support several other enzymes in the body which play a important role in biosynthesis. This also makes optimum use of the vitamin B6 by improving the body metabolism and many other biological process as well. The vitamin B6 traditionally comes in the form of pyridoxine hydrochloride which the body finds difficult to synthesize in its existing state. Hence, this pyridoxine hydrochloride is processed and is formed as Pyridoxal-5-phosphate to help the body to use the vitamin B6 effectively.

There are a lot of benefits of the vitamin P-5-P

Let us have a look at some of them.

Pyridoxal-5-phosphate uses the information from the genes ad helps to produce proteins.P-5-P is also helpful in the formation of hemoglobin, histamine and neurotransmitters and is also helpful in the metabolism of amino acids, fats and glucose.Pyridoxal-5-phosphate also helps in the conversion of dopa which is a useful substance used in the treatment of Parkinson's disease. Dopa is converted to dopamine which is a neurotransmitter which is produced in the brain and is released by the hypothalamus.

Food Source

The P5P is also helpful in the utilization of the food sources for the formation of energy and also helps in the easy release of glycogen which is the stored energy.P5P also converts glutamate into GABA which is gamma amino butyric acid which is again a neurotransmitter which is known to be found in the mammals. This is found in their central nervous system.The Pyridoxal-5-phosphate also helpful in the process of decarboxylation which is the conversion of histidine to histamine.

This also converts SAM-e to propylamine which is known to be a precursor of polyamines.The Vitamin P5P is also responsible to lower the homocystenie levels which are caused by the intake of high amounts of methionine.The Vitamin Pyridoxal-5-phosphate helps in the treatment of irregular heartbeat , which is a condition termed as arrhythmia.This plays a important role in the treatment of myocardial infections. This prevents the blood platelets from sticking to each other which usually causes blood clots.The enzymes produced by the Pyridoxal-5-phosphate also helps in the formation of different kinds of amino acid reactions which keeps the carbon ions stable. This process is very important in the metabolism of the cells.The P5P also helps in the metabolism of the amino acids.

Here it helps in converting methionine to cysteine and also converts tryptophan to niacin.Pyridoxal-5-phosphate also plays a vital role in the formation of glucose. This process is known as gluconeogenesis.This also acts a important co-enzyme in the process of glycogenolysis which happens in the liver and muscles and this is known to be a reaction which occurs due to presence of glycogen.The P5P also helps in the formation of antibodies and also assists in the process of hemoglobin synthesis as well.

To keep it simpler, the vitamin P5P performs many functions which is very beneficial to the whole human body. The P5P deficiency can also happen in many individuals and even such symptoms are hard to identify. Any person suffering from the P5P deficiency will have symptoms like muscle weakness, irritability or depression. Consulting a physician and taking necessary supplements will help to overcome the P5P deficiency.

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Date: August 29, 2011 10:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Vitamins And Minerals Are For Mental Alertness?

There are many vitamins and minerals which can help improve the health and functioning of the nervous system. Vitamins and minerals are significantly involved in many biological processes of the body. It influences the activities of the organs of the body including the brain. In fact, deficiencies on vitamins and minerals may result to psychological or even psychiatric symptoms in certain individuals. People with psychiatric problems are also prescribed with vitamin and mineral supplements which serve as one of its conventional treatment.

The vitamins and minerals which are good for the improvement of brain function and improvement of mental alertness are the following:

1. THIAMINE OR VITAMIN B1. Generally, insufficient amount of this enzyme may result to mild psychiatric symptoms. Studies revealed that people with inadequate amount of this vitamin has the symptoms of fearfulness, anxiety, depression, agitation and behavioral instability. This vitamin is necessary for the activity the body’s enzyme called pyruvate dehydrogenase. This enzyme is required for the conversion of pyruvate to acetyl – coenzyme A. If pyruvate is not catalyzed into acetyl – coenzyme A, the excess pyruvate in the body might be converted into lactate which can cause muscle pains and also psychiatric symptoms such as anxiety. Deficiency of this vitamin must be suspected when the person is alcoholic or malnourished.

2. RIBOFLAVIN OR VITAMIN B2. This vitamin is closely associated with major depression in relation to oxidative stress. Riboflavin is required for the metabolism of protein, fats and carbohydrates. The building blocks of these macronutrients are important for the maintenance of brain health and proper functioning of the nervous system. It can improve the energy levels and functioning of the brain, thus improving an individual’s mental alertness.

3. pyridoxine OR VITAMIN B6. Studies show that low level of vitamin B6 is directly related to depression. Inside the body, pyridoxine is converted into its biochemical active form called pyridoxal phosphate which is important for mental alertness and brain functioning. pyridoxine acts as a coenzyme involved in the synthesis of brain chemicals such as serotonin, dopamine and gamma aminobutyric acid (GABA). This vitamin is also involved in the metabolism of carbohydrates and amino acids which are essential for boosting energy levels.

4. COBALAMIN OR VITAMIN B12. Deficiency of this vitamin is closely related to decrease mental functioning. Vitamin B12 is a cofactor of the enzyme methionine synthase which is important in the conversion of homocysteine to methionine. This is required for the production of energy in fatty acids and proteins which is important for the methylation reactions of brain chemicals.

5. VITAMIN C. This vitamin is considered to be a cofactor of the neurotransmitter dopamine and is involved in the conversion of dopamine to norepinephrine. These brain chemicals are important for the maintenance of proper mental alertness.

6. FOLATE. Decreased mental alertness and depression is a common symptom of low levels of folate in the body. This mineral is involved in the methylation and synthesis of DNA. It is important for the development of brain function and improvement of mental alertness.

7. MAGNESIUM. This mineral is involved in many reactions of the body. Individuals with decreased mental alertness are found to have low levels of magnesium in their cerebrospinal fluids.

8. ZINC. This is a mineral which is important in the catalyses of many enzyme sin the body. It is found in high amount in the brain which is important for nervous activities.

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Date: April 18, 2011 02:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Royal Jelly Really Boost Energy?

Royal Jelly as an Energy Boost

Royal jelly is an all-natural animal product entirely derived from the secretions of honey bees. It is commercially touted as an energy booster because of its unique combination of compounds that help produce energy in cells and promote mental clarity. It contains an abundance of monosaccharides, amino acids, fatty acids, trace minerals, and enzymes, all of which have bioactive properties.

Inside a honeycomb, royal jelly is obtained from queen cells. These secretions are actually fed to all larvae, but only queen larvae are fed with royal jelly in amounts that can be harvested. This is the reason why royal jelly is considered rare. That being said, recent innovations in the manufacture of honey and the overall beekeeping process have contributed to increasing productions of royal jelly.

Contains Vitamins and Minerals

Royal jelly is available as a dietary supplement noted for its high vitamin and mineral content. It is a natural source of vitamin B complex, notably pantothenic acid (vitamin B5) and pyridoxine (vitamin B6). It has relatively high amounts of simple sugars and fatty acids, both groups are biological precursors of cellular energy. In general, it contains up to 15 per cent carbohydrates and 5 per cent healthy fats.

In addition to vitamins, it is also rich in enzymes that are believed to aid the fast absorption of its bioactive compounds in the small intestine. In addition, it contains trace amounts of dietary minerals. Royal jelly is often marketed as a fast-acting energy booster because its components are believed to work synergistically in the prompt release of energy within cells right after absorption.

Improves Energy Metabolism

Coenzyme A is an organic compound produced in the human body to aid the metabolism of cellular energy. Its synthesis, however, requires the presence of pantothenic acid, a vitamin obtained largely from the diet. It is postulated that royal jelly helps increase the production of energy in that it contains pantothenic acid in amounts sufficient to affect the biosynthesis of coenzyme A.

Royal jelly is also noted for its pyridoxine content. Pyridoxal phosphate, or pyridoxine, is the active form of vitamin B5. It is necessary for the metabolism of protein, glucose, and lipids. It is of special significance in yielding energy from glycogen, which it converts to glucose. The combination of fatty acids, simple sugars, and B vitamin in royal jelly enables it to bring about a noticeable energy boost.

Creates Feelings of Well-being

Royal jelly has been linked to an increase in the release of major neurotransmitters, especially serotonin, dopamine, and glutamate. Serotonin is dubbed the happiness hormone. Dopamine is linked to rewards-seeking behavior and keeps interest in repetitive tasks. And glutamate is a major excitatory neurotransmitter in the central nervous system. Together they sustain mental focus.

The roles of its components and their metabolites in the production of energy and release of brain chemicals are the reason why royal jelly creates feelings of physical and mental well-being.

Royal Jelly Use It

As you can see, royal jelly is rich in many nutrients to support a health brain and metabolism. If you are seeking more energy, give royal jelly a try!

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Date: February 03, 2011 12:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why Should I Be Taking A Vitamin B-Complex?

Vitamins are vital to life. They are essential organic nutrients that are required in very small amounts. Each vitamin is responsible for a certain metabolic function. Vitamins, except for Vitamin D, are not synthesized by the human body and thus are essential nutrients that must be provided through diet or supplements. Vitamins have two categories based on their solubility, the water – soluble and the fat – soluble. Water – soluble vitamins comprise of the B – complex vitamins, vitamin C and choline. On the other hand, the fat – soluble ones are vitamins A, D, E and K. In this article, we will focus on vitamin B – complex which are water soluble.

Vitamin B – complex include thiamine, riboflavin, niacin, pyridoxine, folate, cobalamin, biotin and pantothenic acid. These vitamins are crucial to many biologic processes:

Vitamin B-1 or thiamine is plays a role in energy metabolism and nerve functioning that is associated with muscular movement.

Vitamin B-2 or riboflavin also acts as a coenzyme in the release of energy from nutrients just like thiamine.

Vitamin B 3 or niacin is also very important in energy metabolism, specifically in glycolysis and tricarboxylic acid (TCA) cycle.

Vitamin B5 or pantothenic acid is involved in the normal growth and development of cells.

Vitamin B6 or pyridoxine acts as a catalyst in protein metabolism. This is essential in the development of nerve cells and normal functioning of the nervous system.

Vitamin B7 or biotin aids the transfer of carbon dioxide from one compound to another. It also assists the body to make hormones.

Vitamin B9 or folic acid helps maintain a healthy DNA and is required in the production of red blood cells (RBC).

Vitamin B12 or cobalamin is important in the growth and development of tissues and organs. It is also needed in the production of RBCs and nervous system functioning.

These vitamins are found almost in all foods, yet no one food is a perfect source of all these essential vitamins. Fruits and vegetables, cereals, meat and dairy products are great sources. Experts suggest that it is always best to consume vitamins from food sources. However, deficiencies may be rampant if you would just depend on dietary sources. These vitamins work hand in hand that an insufficiency in any B vitamin may result to poor functioning of any or all of the other B vitamins even if they are in good supply. Good thing, vitamin B – complex is made available to supplement the diet. These supplements come in capsule or tablet preparations. Inadequate levels of B vitamins may cause a feeling of weakness, tingling sensation and numbness in both upper and lower extremities, muscle cramps, hair loss, nail brittling, abdominal pain, depression, anemia, poor growth and development in children, and birth defects. As mentioned above, B vitamins are water – soluble. This means that the body cannot store this kind of vitamin except for vitamin B12 and any excess will be readily excreted in the urine. That’s why for those who are taking vitamin B – complex, it is safe and normal to have a bright to dark yellow – colored urine.

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Date: September 03, 2010 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Beef Liver Is Nutritous For You

Beef Liver Health Benefits

Beef liver is packed full of nutrients, including significant quantities of several B vitamins: B1 thiamin), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), B12 (cobalamin) and folate. It also contains large amounts of Vitamin A - in fact the liver of the polar bear contains so much Vitamin A that it is toxic to humans and eating its liver can be fatal. Vitamin C is another vitamin, and beef liver also offers a number of useful minerals, such as phosphorus, iron, zinc and copper.

However, liver is available in a number of forms: raw, cooked or as desiccated raw beef liver granules. The Argentineans often eat their beef liver raw or only slightly cooked, and they get the best deal as far as nutrition is concerned. That is because cooking destroys Vitamin C and thiamin and so, if you do not like eating raw liver, Argentinean Beef Liver granules are likely the best form in which to take this very nutritious food source.

Beef Liver Supplements

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Date: November 24, 2008 04:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin B Complex

The connection between B vitamin complex and stress is well known; although why a good B vitamin complex can reduce stress is less well known. Before discussing the reason why a Vitamin B formula can reduce stress, we shall first have a look at stress and what causes it. The term means different things to different people, and a stressful situation to one person might not be such to another.

The biochemistry of stress is fairly complex, although involves the production and release of hormones into your bloodstream. When an event occurs that causes stress, the hypothalamus portion of your brain becomes involved. It releases cotocotropin releasing factor (CRF), a hormone that protects you from stress by raising your spirits. CRF sends signals to the pituitary gland causing the release of ACHT (Adrenocorticotropic hormone corticotropin) that causes cortisol to be released into the bloodstream by the adrenal glands. Cortisol speeds up the metabolism.

Coincidentally, the cells of the brain stem and spinal cord send a message that stimulates the adrenal glands to secrete epinephrine that increases the heart rate, breathing and alertness, ready for fight or flight. Both of these mechanisms then lead back to the pituitary gland and your new stress level can repeat the process or stop it, should your stress be reduced. If this cycle continues over an extended period of time it can have serious repercussions on your mental and physical health.

The B vitamins can help to regulate this biochemical function, and in doing so can reduce stress, and with it the associated anxiety and depression. In fact many of the symptoms of vitamin B deficiency are those that are also associated with stress: anxiety, nervousness, depression irritability and so on. There is no one specific form of Vitamin B that helps with stress, and there are eight in total. However, in saying that, the three members of the B vitamin complex that have most effect on stress are vitamins B 3, 6 and 12.

Every one of the B vitamins is involved in cell metabolism. Because they are soluble in water, they are quickly leached from the body so have to be replaced on a regular basis. The various B vitamins are needed by your body for specific purposes, such as Vitamin B1 (thiamin) is essential for the correct function of your nerves, brain and muscles. Although others have their own particular areas of responsibility, they are generally lumped together, not only because they are all soluble in water, but also because they each have a profound effect on the metabolism of your body.

Those mostly connected with the nervous system are Vitamins B3, B6 and B12. Vitamin B3 (Niacin) helps to maintain the proper health of your digestive system, skin and nerves, and B12 (cobalamin) is also needed for a healthy nervous system. Vitamin B6 (pyridoxine) along with vitamin B12 are the two principal members of the B complex that have an effect on stress, and a deficiency of these can make you more prone to this frequently debilitating condition. In fact many people that are suffering from a general Vitamin B deficiency have various forms of mental problems.

Because Vitamin B12 is available only from animal sources, deficiencies are common in vegetarians, and even more common in vegans who are advised to take a Vitamin B12 supplement. However, in general you are best to take a Vitamin B complex as opposed to a supplement of any specific member of the B family. This is because a surplus of any one could lead to a depletion of others.

It is thought that much of today's stress is caused by an inadequate diet, and a diet deficient in various forms of Vitamin B is believed to render the subject particularly prone to stress and anxiety. People that have been suffering undue levels of stress over a protracted period of time can be helped by a regular treatment of B vitamins. In taking such supplements, however, you should also be aware of the various possible effects on your body that the causes of your stress can have. These are frequently neither understood nor recognized when they occur.

For example, if you are under stress due to a poor diet, or conversely, are eating a poor diet due to your high stress levels, you might be building up fatty deposits in your liver. Because of this your general health could be at serious risk in addition to your mental health. It is important, therefore, that you don't just restrict yourself to a B vitamin complex, but also take a supplement containing inositol and choline bitartrate.

These can reduce the fatty deposit that a poor diet can cause to build up in your liver with consequent risk to life. Such deposits affect the ability of your liver to destroy the environmental toxins to which become exposed as part of your daily life, and which can be directly related to your ability to counter high stress levels.

In general, however, if you are prone to stress and get nervous and worried about the slightest thing that doesn't go to plan, a B vitamin complex can help: vitamin B can reduce stress, although if your stress is sever you would be better advised consulting a physician than a health store.

Stress is a serious condition, and not one that should be treated lightly. It is possible to treat some stress conditions by using a good B vitamin complex, although should the stress be serious then you should consult your physician. Frequently the stress is not diet related, but due to personal circumstances that cannot be cured by any form of supplement.

However, there are few doubts that a course of Vitamin B supplements can help to overcome many of the metabolic causes of stress, and make up for any deficiency in these vitamins that leave your body almost as quickly as they enter it. Vitamin B can reduce stress, but only if your stress is due to a deficiency: and this is more common that most people are aware.

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Date: June 23, 2008 03:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: B Vitamin Complex

The vitamin B supplement you take is a mixture of nutrients that, although they share the same vitamin letter, are in fact distinctly different chemical entities. The reason that they share the same reference letter of the alphabet is that they are all essential water soluble vitamins (Vitamin C being the only other), they frequently work in synergy with each other and they often come from common sources and have similar properties in the body. They were therefore at one time believed to be just the one chemical entity.

They are essential in that they must form part of our diet because our bodies cannot manufacture these substances from others, and although most share common biochemical and health functions, there is no health function that requires all of them, and none of them can be totally replaced by another.

The B-Vitamin complex that you take can consist of as many as eight different B vitamins, each of which is essential for a healthy body and at one time it was believed that this mixture was only one single vitamin. That is why they are collectively known as vitamin B and were subsequently allocated numbers: it was only later that the individual components were discovered.

These eight are vitamin B-1 (thiamine), vitamin B-2 (riboflavin), vitamin B-3 (niacin), vitamin B-5 (pantothenic acid), vitamin B-6 (pyridoxine), vitamin B-12 (cobalamins), biotin and folic acid (folate). They are found in yeast, liver, tuna, bananas and rice among other sources, and, as with all vitamins, without them life would not be possible. Not all vitamins are found in each of these food sources, and vitamin B-12, for example, is available in nutritional quantities only from animal sources.

Knowing what they are is all very well, but what does your body do with the B vitamin supplement that you take? Before considering that, the reason that a regular supply is important is because of their water solubility. This is a useful property for a vitamin to possess, because it means that they can easily be transported by the body fluids to the tissues where they are needed. The downside, however, is that they are consequently also easily flushed from the body, and your body cannot store any of the B vitamins.

You therefore must have a regular dietary source that can be augmented through supplementation. This is particularly desirable in alcoholics, those on diets to lose weight and vegans who are advised to take a regular vitamin B-12 supplement.

A lack of vitamin B will make you feel tired and lack energy because they play a big part in your body’s metabolism of blood glucose into energy. They also help to maintain a healthy immune system, keep your nervous system in tip-top condition and maintain good healthy skin, hair and muscles. The B complex is also very important in maintaining healthy blood and liver, and each and every component of the mixture has a specific part to play, both on individually and by interaction with others in the B complex.

Rather than examining what your body does with the supplement as a whole, let’s have a look at each component, and what your body does with that. Taking them one at a time, thiamine (B1) helps you to burn carbohydrates to generate energy. It is highly water soluble and must be taken daily. In the form of thiamine pyrophosphate it plays a key part in the metabolism of carbohydrates to energy, and also in the metabolism of certain amino acids. If you rely heavily on a high carbohydrate diet, you will need a good regular supplement of thiamine to be able to convert them to energy.

Vitamin B2 (riboflavin) also plays a part in fat and carbohydrate metabolism and the formation of adenosine triphosphate (ATP), the molecule of energy. It plays a significant part in the health of your skin and a deficiency is associated with mouth ulcers, cracked lips, flaky skin and bloodshot watery eyes. It also activates vitamin B6 and folic acid, one of the cases where the B vitamins work together synergistically.

Vitamin B3, or niacin, is well known to women as a component of some shampoos, and helps to promote health hair. However, this vitamin also takes part in the process of energy creation within your body, and helps to maintain a good muscle tone within the digestive tract. It is also used as a supplement for the treatment of diseases related to high levels of LDL cholesterol and is useful for the treatment of atherosclerosis.

Pantothenic acid is also found as a component of shampoos, so no prizes for guessing one of its functions. Vitamin B-5 plays a significant part in the energy-producing Krebs Cycle, or Citric Acid Cycle, that is used by every cell in your body to generate energy just where it is needed. It is also needed to synthesize acetylcholine, a neurotransmitter needed for good brain function and it helps to reduce stress. Pantothenic acid is also closely involved in the production of cholesterol in your liver: cholesterol is not all bad, and is needed by your body to produce some of the steroid hormones and also vitamin D.

Amino acids are the small units that are used to biosynthesize proteins and ultimately the genes and DNA that determine who you are. The major factor involved in processing these amino acids is Vitamin B6 (pyridoxine), one of the lesser known of the vitamin B complex. It synthesizes and breaks up different amino acids to produce a variety of other compounds, such as the hormones serotonin, melatonin and dopamine.

Deficiencies in these hormones can be very serious, Parkinson’s disease believed to be connected with a dopamine deficiency for example, and other disorders include kidney stones, anemia and many skin complaints. Although deficiency of vitamin B6 is rare, it can occur in alcoholics and those with chronic kidney problems. It is believed that many diets are deficient, however, and a good vitamin B supplement would ensure that this did not occur.

Vitamin B-12 is one where deficiency can occur, particularly in alcoholics and vegans. It is available in sufficient quantities only from meat sources, and a supplement is indicated in anyone with a low meat intake in their diet. It is used by your body for the replication of DNA and to allow the normal activity of your body cells. It also helps to control homocysteine levels in conjunction with vitamin B6 and folic acid: homocysteine is a high-risk amino acid associated with atherosclerosis and cardiovascular disease that can lead to Alzheimer’s disease, heart attacks and strokes.

The seventh, biotin (sometimes referred to as vitamin B7) also takes part in the metabolism of energy, but deficiencies have not been known, and the final known member of the B vitamin complex is folic acid. This is essential for cell growth and the synthesis of RNA and DNA in the body. RNA (Ribonucleic acid) is responsible for the synthesis of proteins in your body, and the well known Deoxy-ribonucleic acid (DNA) holds the genetic information of your body. Folic acid is therefore essential in the growing fetus, and any other cellular system that rapidly regenerates such as blood cells and the various cells of the immune system.

Without folic acid your body would be more susceptible to bacterial and viral attack, and less able to protect you from foreign invaders into your body tissues. Although deficiency is not common, folic acid is present in fresh food only and degrades when stored at room temperature and when cooked. A supplement is therefore advisable during pregnancy to help to prevent neural tube defects.

It is evident that the Vitamin B complex plays many parts in the chemistry of your body, and that a supplement can be of benefit in assuring that there are no deficiencies. A good B complex can be found at your local or internet health food store.

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Date: June 19, 2008 12:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: B Vitamins

The B vitamins are integral to body growth and development. They play a great part in the activities of enzymes that regulate chemical reactions in our body. Different B vitamins exist in various animal and plant foods. Examples of some of these are cereals and whole grains, pork, seafood, eggs and liver. They are also in dairy products, dried beans, chicken, watermelon and grapefruit to name a few among the many sources. Supplements are another great way to ingest B vitamins.

These vitamins consist of a group of eight water-soluble nutrients:

* B1 – Thiamine * B2 – Riboflavin * B3 – Niacin * B5 – Pantothenic Acid * B6 – pyridoxine * B7 – Biotin * B9 – Folic Acid, Folate * B12 – Cobalamin

When the body takes in these B vitamins, it uses them in different ways. The body uses B1 and B2 to affect enzymes (proteins) that have an influence on muscles and nerves. When B1, thiamin, enters the system, the body uses it to help convert glucose into energy. It uses B2 to help repair hair, skin and nails. Vitamin B3 helps maintain skin health and digestive functions. This vitamin also helps maintain the health of the body's nervous system. Vitamin B5 affects the body's normal growth and development overall.

The body uses B6 to break down protein and to maintain the health of the red blood cells. It also uses this kind of B vitamin to keep the nervous system and components of the immune system healthy. The B7 vitamin helps the body produce hormones. It also helps it break down carbohydrates and proteins. The B9 vitamin also helps the production of red blood cells. The body uses B9 in its cells so they can manufacture and maintain DNA. This DNA contains the genetic instructions used in the development and functioning of all living organisms known to man. The body uses vitamin B12 to help produce blood cells and uses it in nervous system functions.

Since the B vitamins are water-soluble, they do not remain stored in the body if too much of them are ingested. The exceptions are B12 and folate (B9), which the liver stores. The body eliminates most of any extra amounts of the rest of the B vitamins through the urine. However, it's wise to take only what your particular system requires when it comes to these vitamins.

Because the body uses the B vitamins to aid so many vital functions, certain things happen when the body does not get enough of them. Some people may experience numbness and tingling in their arms and legs if they're deficient in B vitamins. Muscle cramps can occur as well as tiredness. Anemia is a concern if a person does not get enough of these vitamins, as is depression. Loss of appetite and abdominal pain are symptoms of vitamin B deficiency as well. Therefore, it is important that one ingest the B vitamins on a regular basis.

Just eating foods that contain these B vitamins prepared in any manner is not enough. Because the body uses these vitamins to support important functions, it needs them in full measure. Extended cooking times and food processing can dilute the strength and concentration of these vitamins. Alcohol can diminish their useful effects too.

The right amounts of B vitamins on a regular basis are part of a comprehensive health strategy. The body uses the required amounts efficiently to promote overall health. Used in conjunction with the other vitamins and minerals we need, the B vitamins can make daily living that much more energetic.

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Date: May 07, 2008 03:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: B Vitamin Supplements

The fact that B vitamins have had to be coenzymated before they can be used by your body has been known for some time, but it is only over the past few years that they have been made commercially available in that form. Before we discuss the B vitamins in their coenzyme form it might be appropriate to discuss what coenzymes are and how they differ from ordinary enzymes.

An enzyme is like an organic catalyst: it takes part in biochemical reactions by allowing such reactions to take place, but itself remaining unchanged. All enzymes are proteins formed in your body from amino acids and other protein material. A coenzyme, on the other hand, is somewhat like an enzyme for the enzymes, in that it is needed for the enzyme to do its job. Without a coenzyme, many enzymes could not promote the biochemical reaction it is responsible for.

The B vitamins are all water soluble, which means that they are readily excreted and it is not impossible that if you take a B vitamin supplement, the whole lot will be immediately excreted in your urine if not used by your body. Whether they are or not it is a fact that your body can quickly become depleted of the B vitamin group, especially if you drink a lot. Alcoholics in particular are frequently vitamin B deficient. Although the liver can store unused vitamin B, they are only very small quantities and insufficient to prevent a deficiency.

A deficiency in the B vitamins can cause a wide range of unpleasant conditions that are rapidly remedied with supplements. Pellagra is due largely to a deficiency in Vitamin B3, and causes hair loss, horrible skin lesions and many other side effects that you don’t want to know about. Vitamin B12 deficiency can cause loss of memory, and is common in alcoholics and some vegetarians (vitamin B12 is animal derived). Other symptoms of a general B vitamin deficiency include exhaustion, heart palpitations, fibrillation, anxiety, restlessness, attention deficit disorder and many, many more.

It is not pleasant so you make sure that take enough vitamin B in your diet: dietary sources are far superior to pills although supplements will help you get over the symptoms of the deficiency until your diet takes over. Supplementation is also a good way to maintain a regular supply of vitamin B complex irrespective of your diet. The effects of a deficiency are so bad that a regular supplement is well worth taking.

However, back to coenzymes and why they are needed for the metabolism of B vitamins in your body. Most B vitamins are, in fact, coenzymes themselves. Keep in mind that the definition of a vitamin is an organic substance that is essential for the normal health of your body. If you lack even one vitamin, your health with suffer and eventually you will be likely to die. That describes all of the B vitamins perfectly, and they also just happen to be coenzymes. This is not coincidence, of course, and their biochemistry must have been recognized before the concept of coenzymes was formulated.

The B vitamins proper consist of eight distinct proteins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), B9 (folic acid), B12 (cyanocobalamin), and biotin and pantothenic acid. They are all essential components in human and animal metabolism, and most are also coenzymes.

Every cell in your body depends on B vitamins for its existence, which is why pregnant women should include a good supply of them in their diet, especially folic acid (B9). They are essential for the cellular development of the fetus. Folic acid is necessary for the synthesis of nucleic acids that allow cell growth and the production of red blood cells. However, not one can be placed in importance above any other since they are all essential.

With respect to the coenzyme factor, the vitamin B coenzymes are responsible for many of the biochemical reactions upon which life depends. Coenzyme B-12 for example is essential for two types of reaction that it catalyzes, one being a hydrogen atom exchange with alcohol and amine functional groups, the other being connected with methyl group transfer between molecules.

In humans, the first of these is responsible for an essential step that results in energy being metabolized from fats and proteins in the mitochondria and the second for DNA production in cells that is indirectly responsible for growth. Each of these is why a vitamin B-12 deficiency leads to excessive fatigue and also a lack of fetal growth (although folic acid can make up for the latter deficiency).

Thiamine (Vitamin B1) is a coenzyme for the metabolism of carbohydrates to energy. In the body it is present in the form of thiamine diphosphate, a coenzyme that assists in the decarboxylation of pyruvate as part of the citric acid cycle, otherwise known as the Krebs Cycle, that takes place in the mitochondria and is responsible for the generation of energy through aerobic respiration.

Another coenzyme that is involved in the Krebs Cycle is formed in the body from Vitamin B3, or niacin. This coenzyme, nicotinamine adenine dinucleotide, has a redox potential and can store energy for use later on. Vitamin B5 can be converted in the body to Coenzyme A that not only breaks proteins down into individual amino acids, but also takes part in the first part of the Krebs Cycle. There is a common pattern emerging here where the B vitamins have an important part to play in the generation of energy from fats and carbohydrates.

Similarly, Vitamin B6 is present in the body as the coenzyme Pyridoxal 5'-phosphate that helps to break down the body’s emergency energy store, glycogen, into energy when needed.

In these ways, and more, the coenzymes created in the body from the B vitamins help many of the reactions of life to take place, and without these coenzymes life could not exist. Hence the importance of the B vitamins themselves, and any deficiency could be disastrous to the metabolic processes that generate energy and keep you alive. It is not just the energy needed for exercise and normal human activity that will be compromised, but also that which keeps the heart beating and your diaphragm moving to allow you to breath.

Without a doubt, a Vitamin B supplement is one of the most valuable of all the vitamin supplements, and they are available in many forms. You might also find some of the B vitamins in their coenzyme form, though some of them may be unstable. However, whatever form they are taken in, Vitamin B complex should be one of the first on your vitamin supplement shopping list.

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Date: April 18, 2008 03:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supports Healthy Blood Pressure

• A comprehensive Bio-Aligned Formula™ that can help maintain blood pressure already within the normal range, when used as part of a healthy diet and exercise plan.
• A complex array of 35 nutrients, botanicals and special ingredients provides balanced support for blood pressure.
• Supports two of the most important SystemiCare™ metabolic systems identified by Source Naturals as critical for your optimal health: Heart/Circulation (including healthy blood vessels, blood flow, homocysteine levels, and blood lipid regulation) and Antioxidant Defense.

3 tablets contain:
(Vitamin C (as ascorbic acid) 45 mg
Vitamin D-3 (as cholecalciferol) 240 mg
Vitamin B-6 (as pyridoxine HCl) 24 mg
Folate (folic acid & calcium folinate) 480 mcg
Vitamin B-12 (as methylcobalamin) 600 mcg
Magnesium (magnesium oxide, chelate & succinate) 240 mg
Selenium (as L-selenomethionine) 120 mcg
Potassium (as potassium citrate) 59 mg
L-Arginine (as L-arginine HCl) 1.44 g
L-Citrulline 360 mg
Hibiscus Flower Ext (20% total acids) 120 mg
gamma-vitamin E Complex 90 mg
L-Taurine 60 mg
Masson Pine Bark Extract(95% procyanidolic value) 60 mg
Garlic Clove 60 mg
Freeze Dried White Onion Bulb 60 mg
Arjuna Bark Ext (0.5% arjunolic acid) 60 mg Ashwagandha Root Extract(5% withanolides) 60 mg
Forskohlii Root Extract(ForsLean®) (20% forskohlin) 60 mg
Guggul Extract (10% guggulsterones) 60 mg
Grape Seed Extract (Proanthodyn™) 48 mg
Chinese Salvia Root Extract (MSV-60®)
(60% magnesium salvianolate B) 45 mg
Ginkgo Leaf Extract (50:1)
24% Flavoneglycosides 36 mg
Hawthorn Berry Extract (4:1) 30 mg
Hawthorn Leaf and Flower Extract (4:1) 30 mg
Olive Leaf Ext. (15% Oleuropein) 30 mg
Trimethylglycine (TMG) 30 mg
Total Resveratrols (from Polygonum cuspidatum) 24 mg
Nattokinase (NSK-SD™) 21 mg
Coenzyme Q10 18 mg
Tocotrienol Complex (Tocomax®) 12 mg
Lycopene 3 mg

Suggested Use: 3 tablets mid-morning and 2 tabs mid-afternoon between meals on an empty stomach.

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Date: March 26, 2007 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supplements good for reducing stress and boosting energy!

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Date: March 16, 2006 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL Booster - Boost your good cholesterol

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Date: February 16, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Instant Energy B-12 2000mcg per serving 75 packets/Box

Of all the vitamins, minerals, herbs and specialized dietary supplements at the disposal of the health-conscious public, not a single one can mirror the biological complexity of Vitamin B-12. It is involved in thousands upon thousands of chemical reactions throughout the body, and its presence has a direct influence on energy, red blood cell production, metabolism, central nervous system function, cardiovascular health, cognitive function, emotion, DNA repair and digestion, just to scratch the surface.*

Our researchers and product formulators had one goal in mind – to develop a vitamin B-12 formula that was superior to anything to precede it – a potent, fast-acting B-12 complex capable of expediting delivery while maximizing uptake. After months of research and development, this was accomplished by uniting cyanocobalamin (the primary form of B-12) with the vitamin’s two co-enzyme forms (methylcobalamin and dibencozide) in perfect balance. But we didn’t stop there. To further enhance the activity of this one-of-a-kind formula, we merged the three with a group of proven synergists that includes Chromium Picolinate, Creatine Monohydrate, and a optimally balanced arrangement of 6 additional B vitamins.

It’s clear that B-12 plays a vital role in human health. Unfortunately, many consumers might not be aware of just how vital it is. As we age, it becomes increasingly difficult for the body to properly utilize, and is almost non-existent in many processed foods. This makes B-12 especially important for people over the age of 50, as well as vegetarians, those who regularly consume fast and processed foods, social drinkers and individuals who live with digestive challenges. Simply put, you can feel completely confident recommending NOW® Instant Energy B-12 Packs to virtually any customer trying to take charge of their health.*

NOW® Instant Energy B-12 makes it simple to get the B-12 they need to function at their absolute best. NOW’s unique collaboration of all three B-12 forms goes to work quickly to effectively boost energy, support cognitive health, promote normal homocysteine conversion and support healthy red blood cell production. Our convenient packets can be taken throughout the day, and are perfect for the office, the car or when traveling.*

Serving Size 1 Packet
Thiamine (from Thiamine HC1) 1.5 mg
Riboflavin (Vitamin B-2) 1.7 mg
Vitamin B-3 (as Niacinamide) 20 mg
Vitamin B-6 (from pyridoxine HC1) 2 mg
Folate (as Folic Acid) 400 mcg
Vitamin B-12 2 mg (2,000 mcg)
Cyanocobalamin 1.4 mg (1,400 mcg)
Methylcobalamin 300 mcg
Dibencozide 300 mcg
Vitamin B-5 (from Calcium d-Pantothenate) 30 mg
Chromium (from Chromium Picolinate) 60 mcg
Creatine Monohydrate 250 mg

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Date: December 07, 2005 02:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: TMG Fact Sheet

TMG Fact Sheet

LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups.

MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine.

TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals.

Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot.

ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid.

TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures.

DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably.

SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed.

COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement.

People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG.

This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

General:

Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791

Methylation:

Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review].

Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30.

Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review].

Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31.

Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61.

Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5.

Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93.

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

Homocysteine:

Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8.

Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361

Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203

Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83.

Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50.

Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53.

Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499

Liver function:

Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German].

Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2.

Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.

Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329

Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277

Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.

Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887

Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612

Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.

McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907

Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55.

Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439

Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German].

Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644

Autism & Seizures:

Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1.

Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82.

Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6.

Immunity:

Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6.

Safety:

Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082

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Date: November 18, 2005 10:21 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: B-Complex 50mg Energy

Complete List of Nature's Life Vitamins here!

Master the Art of Energy!

With Nature's Life B-complex 50 Energy

This product has a comprehensive B-vitamin and herb combination, B-complex vitamins are intended to provide nutritive support for many aspects of health, including but not limited to: metabolism, energy, nervous system, homocysteine levels, muscle tone, skin and hair.

also added, Green tea, Korean Ginseng and Gota kola as anti-fatigue herbal support.

Suitable for Vegetarians

One tablet daily.

Supplement Facts:

• Thiamine (as Thiamine HCL) (B-1) - 50mg
• Riboflavin (B-2) - 50mg
• Niacin (as Niacinamide)(B-3) - 50mg
• Vitamin B-6 (as pyridoxine HCL) - 50mg
• Folic Acid (Folate) - 500mcg
• Vitamin B-12 (as Cyanocobalamin) - 50mg
• Choline Bitartrate - 50mg
• Inositol - 50mg
• L-Taurine - 50mg
• Korean Ginseng (Panax Ginseng)(Root extract) (Supplying 12.5mg Ginsenosides) - 250mg
• Gota Kola (Centella asiatica)(Aerial) - 50mg
• Green Tea (Camellia sinensis)(leaf extract)(Supplying 49mg Polyphenols, 40mg Catechins, 25mg EGCG [Epigallocatechin Gallate])

Boost your energy with Natures life B-Complex 50 Energy!

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Date: October 13, 2005 04:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Comprehensive Prostate Formula-the Clinical Studies

Helps maintain a healthy prostate gland.

Supports normal urinary function.

Comprehensive Prostate Formula-the Clinical Studies

Saw palmetto Extract

Saw palmetto extract is one of the world's leading herbal products for prostate support. Widely-cited clinical studies conducted over the last fifteen years suggest Saw palmetto extract can produce major improvements in prostate-related urinary function. In clinical studies, Saw palmetto extract has produced measurable improvements in urinary functions and prostate size. Quality of life scores have also improved. The results with Saw palmetto extract have been duplicated in open trials and controlled, double-blind studies.11,12,13 For example, in a large open trial, 505 men took 320 mg of Saw palmetto extract daily for three months.1 The results were evaluated with various measurements such as the International Prostate Symptom Score, the quality of life score, urinary flow rates, residual urinary volume, and prostate size. After 45 days these parameters improved significantly. After 90 days of treatment nearly ninety percent of both the doctors and patients regarded Saw palmetto extract as effective as therapy for the prostate.

The changes in prostate health that accompany middle age are related to the hormone DHT, or dihydrotestosterone, a metabolite of testosterone. DHT levels rise, and DHT binds to prostate cells, accelerating growth of prostate tissue. Saw palmetto extract has been shown to inhibit 5 alpha-reductase, an enzyme that controls conversion of testosterone to DHT.14 Experimental evidence suggests Saw palmetto extract blocks the binding of DHT to prostate cells.15 The fatty acids and sterols in Saw palmetto are believed to be responsible for these actions.14,16 These include oleic acid, lauric acid, campasterol, stigmasterol, beta-sitosterol and others. Clinical studies have used extracts containing 85 to 90 percent fatty acids and sterols.

Pygeum Extract

Like Saw palmetto, Pygeum contains natural sterols and fatty acids.2 Although the mechanisms for its effect have not been clearly established, animal experiments suggest Pygeum may work by inhibiting prostate cell proliferation and reducing inflammation.17,18 In several European trials, Pygeum has successfully improved urinary function. In a large double-blind, placebo-controlled study, 263 men were given 100 mg of Pygeum extract a day for 60 days. Urination improved in 66 percent of the men taking Pygeum, compared with 31 percent on placebo, based on subjective and objective tests.19

Nettle Root Extract

Nettles are approved by the German Commission E as effective for relieving inflammation in the urinary tract.20 As far back as 1950, German investigators have observed favorable effects on the prostate with the use of Nettle root. These initial findings have been confirmed through case studies, as well as double-blind studies, published mainly in German medical journals. In a recent double blind study published in the journal Clinical Therapeutics, 134 men took a combination of Nettle root extract and Pygeum extract over a period of 56 days.3 Urination was significantly improved.

L-Alanine, Glutamic Acid and Glycine

As noted above, Drs. Feinblatt and Gant discovered that a combination of the amino acids L-alanine, glutamic acid and glycine has a positive effect on prostate-related urinary function.5 A controlled study of 45 men was conducted to follow up on these initial observations.21 The majority of subjects experienced complete or partial relief in urinary complaints such as nighttime urination and urgency.

Scientific References
1. Braeckman, J., 'The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study,' Current Therapeutic Research 1994: 55(7):776-85.

2. Lawrence Review of Natural Products. Pygeum. Jan 1998. Facts and Comparisons, St. Louis, MO.

3. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses Clinical Therapeutics 1993; 15(6):1011-19.

4. Wagner, H., Willer, F., Samtleben, R., Boos, G. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots Phytomedicine 1994; 1:213-224.

5. Feinblatt, H.M., Gant, J.D. Palliative treatment of benign prostatic hypertrophy. Journal of the Maine Medical Association, March 1958:99-124.

6. Giovanni, E., et. al. Intake of carotenoids and retinol in relation to risk of prostate cancer. Journal of the National Cancer Institute 1995;87(23):1767-76.

7. Wallace, A.M., Grant, J.K. Effect of zinc on androgen metabolism in the human hyperplastic prostate. Biochemical Society Transactions 1975; 3(3):540-42

8. Badmaev, V., Majeed, M., Passwater, R. Selenium: A quest for better understanding. Alternative Therapies 1996; 2(4):59-67.

9. Fouhad, M.T. Selenium and cancer, chromium and diabetes: two trace elements that have merits as dietary supplements in human nutrition. Journal of Applied Nutrition 1979:31(1&2):14-17.

10. Vescovi, P.P., et. al. pyridoxine (Vit. B6) decreases opoids-induced hyperprolactinemia. Horm. metabol. Res. 1985; 17:46-47.

11. Tasca, A., et. al. Treatment of obstructive symptomatology caused by prostatic adenoma with an extract of Serenoa repens. Double-blind clinical study vs. placebo. Minerva Urologica e Nefrologica 1985; 37:87-91.

12. Champault, G., Bonnard, A.M., Cauquil, J., Patel, J.C. Medical treatment of prostatic adenoma. A controlled test of PA 109 vs. placebo in 110 patients. Ann. Urol. 1984; 18(6):407-410.

13. Crimi, A., Russo, A. The use of Serenoa repens extract in the treatment of functional disturbances caused by prostate hypertrophy. Med. Praxis 1983; 4:47-51.

14. NiederprŸm, H.J., Schweikert. H.U., ZŠnker, K.S. Testosterone 5 alpha-reductase inhibition by free fatty acids from Sabal serrulata fruits. Phytomedicine 1994; 1:127-133.

15. Sultan, C., et. al. Inhibition of androgen metabolism and binding of liposterolic extract of Serenoa repens B in human foreskin fibroblasts. J. Steroid Biochem. 1984; 20(1):515-519.

16. Weissner, H., et. al. Effects of the Sabal serrulata extract IDS 9 and its subfractions on 5 alpha-reductase activity in human benign prostatic hyperplasia. The Prostate 1996;28:300-06.

17. Yablonsky, F. Nicolas, V., Riffaud, J.P., Bellamy, F. Antiproliferative effect of Pygeum africanum on rat prostatic fibroblasts. J. of Urology 1997; 157:2381-87.

18. Marconi, M. et. al. Anti-inflammatory action of Pygeum extract in the rat. Farmaci. & Terapia. 1986; 3:135.

19. Barlet, A, et. al. Efficacy of Pygeum africanum extract in the treatment of micturational disorders due to benign prostatic hyperplasia. Evaluation of objective and subjective parameters. A multicenter, randomized, double-blind trial. Wien. Klin. Wocheschr. 1990; 22:667-73.

20. The Complete German Commission E Monographs. 1998, Blumenthal, M., ed., (p.216) Austin, TX: American Botanical Council.

21. Damrau, F. Benign prostatic hypertrophy: amino acid therapy for symptomatic relief. American Journal of Geriatrics 1962; 10:426-30.

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VDiscount Vitamins at itanet ®

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Date: September 10, 2005 02:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Introducing... CardioFit Plus Lozenges!

Is Your Cardiovascular system Fit?

Delicious Homocysteine Lozenges naturally flavored with Orange Creamsicle flavor and REAL orange Juice!

Advanced B-6, B-12, Folic Acid Formula!

30mg TMG and more!

What is Homocysteine?

Homocysteine is an amino acid found in the blood. Healthy homocysteine levels are important markers of normal, healthy cardiac function. Intake of Vitamins B-6, B-12 and folic acid may help provide nutritive support for healthy homocysteine levels. Choline and Trimethylglycine (TMG) act as methyl donors, which can help the body convert homocysteine into methionine.

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Prostate Health Naturally

Date: June 16, 2005 11:11 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Prostate Health Naturally

Nature's Life Prostate Health Options
Prostate Health... Naturally Prostate issues too often put a damper on the activities of men of all ages and they are far more common than previously thought. According to some studies, virtually all men will eventually experience prostate issues. Men with enlarged prostates experience discomforts that may include difficulty urinating, increased frequency and urgency of urination, bouts with sleep-disturbing nighttime urination and lower back discomfort. Dealing with the discomforts from enlarged prostates may be costly, too. Every year about 400,000 men have prostate surgery, adding over $3 billion annually to the national health care bill. Nature’s Life offers several products to support prostate health, including Saw Palmetto as a whole berry concentrate, and three doctor-formulated combinations including Saw Palmetto for supporting prostate health. All of these products are designed to provide nutritive support for: healthy prostate gland function normal urine flow Nature’s Life® Prostate formulas are made from all natural ingredients… only the finest available. Regardless of the formula you prefer, you can always be sure of the same superior quality and consistent results. Prostate function A small doughnut-shaped gland, the prostate surrounds the urethra where it leaves the bladder. The prostate produces an alkaline substance which makes up the largest part of the seminal reproductive fluid (semen). Most men’s prostates start to enlarge at about age 50. As the prostate gland enlarges, it pinches the urethra, causing reduced urine flow and increased discomfort. Research into prostate enlargement is focusing on male hormones, or androgens. In older men, androgen production changes result in higher levels of dihydrotestosterone (DHT), which is produced from testosterone. The prostate is more likely to enlarge when higher levels of DHT are present. The Holistic Approach A unique combination of herbs, amino acids, vitamins, minerals, phytonutrients, and essential fatty acids may help provide nutritional support to maintain good prostate health. Saw Palmetto Berry (Serenoa repens B.) The berries from this small tropical palm contain lipophilic sterols and essential fatty acids, including beta sitosterol. Saw Palmetto extract may also support normal inflammatory response by inhibiting the production of prostaglandins. Research suggests that Saw Palmetto may help to increase urine flow and decreases nighttime discomfort. Saw Palmetto has been the subject of numerous double blind clinical trials. All of these effects of Saw Palmetto make it the key ingredient to support prostate health. Pygeum Bark (Pygeum africanum H.) The bark of this tall African tree contains lipophilic sterols, including beta sitosterol and sitosterone plus unique fatty acids. These ingredients influence prostaglandin synthesis to help provide nutritional support for a normal inflammatory response. Other components of pygeum may provide nutritive support to help maintain normal prostate size. Stinging Nettle (Urtica dioica L.) A common “weed” around the world, stinging nettle has a long history of traditional use to support normal urine flow. Nettle contains substances that may have anti-androgen activity. Many commentators feel that the potential beneficial effects of Nettle extract are increased when combined with Saw Palmetto. Pumpkin Seed (Cucurbita pepo) The seeds of this familiar food is a good source of zinc, phytosterols, and essential fatty acids: nutrients essential to prostate health. Preliminary studies find pumpkin seed extract promising alone, but combinations of pumpkin seed oil with nettle and/or saw palmetto have the potential to help restore and maintain healthy prostate size. Minerals Zinc is concentrated in the prostate gland and is a major constituent of seminal fluid. Zinc appears to play a role in maintaining healthy male hormone balance, possibly by its effect on 5-alpha reductase, the enzyme which produces powerful androgens in the prostate. Preliminary reports suggest that zinc may be helpful in supporting urinary comfort. Copper is added to balance the zinc and prevent a copper deficiency. Active Aminos™ (Glutamic Acid, Alanine & Glycine) These are the three amino acids found in highest concentration in the prostate. A recent study suggested that this combination of amino acids may help support normal urination and urinary urgency. Beta Sitosterol The oil constituents of a few plants, including soybeans, pygeum, and pumpkin seeds, contain a mixture of phytosterols, or plant hormones, that include beta sitosterol. Recent studies have suggested that beta sitosterol may help to support normal urine flow. Research also suggests that beta sitosterol may also support normal prostaglandin synthesis thus normalizing the inflammatory response. Vitamin B-6 (pyridoxine HCl) This essential B vitamin is required for many metabolic processes, including the use of amino acids such as Glutamic Acid, Alanine and Glycine. Lycopene: A valuable addition Lycopene is an antioxidant carotenoid found primarily in most tomato products. In men, lycopene is stored in the prostate and testes, and has been associated with protecting the health of the prostate by acting as an antioxidant. As men age, the level of lycopene is diminished, therefore it should be replaced by food intake or supplements. Several other herbs have traditionally been used for prostate and urinary tract health: Herbs Traditional Indications* Burdock Root (Arctium lappa L.) Contains polyacetylenes, amino acids and inulin for restoring harmony to the body. Cayenne Fruit (Capsicum annuum L. var. annuum) Contains capsaicin and saponins for stimulating blood flow. Goldenseal Root (Hydrastis canadensis L.) Contains alkaloids, including berberine, a powerful tonic for all mucus membranes. Gravel Root (Eupatorium purpureum L.) Contains active volatile oils and flavonoids; for healthy kidney and bladder function. Juniper Berry (Juniperus oxycedrus L.) Contains essential oils, flavone glycosides, organic acids and terpenes for healthy kidney and bladder function. Marshmallow Root (Althaea officinalis L.) Mucilage, containing poly-saccharides and uronic acid for normal urine flow. Parsley Leaf (Petroselinum crispum M.) Contains coumarin and flavonoids for normal urine flow. White Pond Lily Root (Nymphaea odorata) For intestinal cleansing. * These are traditional indications, and Nature’s Life does not guarantee that the indicated herb will have the referenced benefit at the levels provided.
Lifestyle Choices Nutritionists believe that diet and exercise contribute a great deal to the success of natural prostate self-care. In addition to a comprehensive prostate support formula, men should reduce dietary fat, eat more fruits and vegetables and commit to a regular exercise program. This is not just for a healthy prostate, but a choice for a healthier, happier life. The Nature’s Life® brand has three comprehensive formulas with herbs and nutrients intended to provide nutritive support for healthy prostate gland function and normal urine flow, as well as individual supplements to complement these formulas: 800 Prostate Support™ combines standardized extract of Saw Palmetto – the choice for a stronger dosage – with Stinging Nettle, standardized Pygeum bark extract, and zinc. Prostate 700+™ combines standardized extract of Saw Palmetto with concentrated Nettle root extract, and pumpkin seed oil. 600+ Prostate Maintain™ combines a whole herb form of Saw Palmetto for a regular maintenance dosage with Active Aminos™, Zinc, and a blend of traditional herbs. Saw Palmetto, 500 mg whole herb Lycopene 30 mg & 10 mg
Which Prostate Formula is Best For You? Nature’s Life® Formula/Per Serving 600 700 800 Saw Palmetto 600 mg 213 mg* 160mg* Pumpkin Seed Extract 50 mg 267 mg* Nettle Root Extract 400 mg 150mg Pygeum Bark Extract 10 mg 50 mg -- Vitanet ® (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=368) Energize Your Life! Date: June 14, 2005 05:06 PM Author: Darrell Miller (dm@vitanetonline.com) Subject: Energize Your Life! Energize Your Life! by Laura Weiss Energy Times, December 1, 2003 If every fatigued day leaves you wondering where your energy went, you need a personal energy makeover. "Energy, some special kind of energy, just leaks out and I am left lacking the confidence even to cross the street," Diane Arbus, the photographer, once complained. And while Ms. Arbus tried to overcome her energetic and spiritual ups and downs with her art, you can use lifestyle changes as well as self-expression to revive your vigor. To Sleep, Perchance to Energize When you're looking for a boost in personal energy, you've got to get enough sleep, insists Jacob Tietelbaum, MD, author of From Fatigued to Fantastic! (Avery). Dr. Teitelbaum emphasizes that unless you "give your body eight to nine hours of sleep per night," your personal energy will never be adequate. Studies show that getting less than six hours sleep a night hurts your mental performance and drains your energy (Sleep 3/15/03). As your sleep debt builds up, your energy drops down. "[Our studies show] the importance of sleep as a necessity for health and well-being. Even relatively moderate sleep restriction, if it is sustained night after night, can seriously impair our neurobiological functioning," says Hans P.A. Van Dongen, PhD, Assistant Professor of Sleep and Chronobiology at Penn State. A recent poll by the National Sleep Foundation found that Americans, on average, are getting less than seven hours of shuteye a night. That sleep deficit drains energy. Watered Down Energy Added to that sleep requirement, Dr. Teitelbaum stressed in an interview with Energy Times, a lack of water can deplete your personal energy. "The number one problem is often dehydration," he says. "Make sure you stay hydrated. Although I think it's a bad idea to [obsessively] count glasses of water, you should carry a bottle of water with you, check your lips and if they feel dry drink more water." Overall, your body is about 60% water and 70% of your muscles consist of water. If you let your water levels dip too low, your muscles suffer and your energy levels dip as well. Research shows that as your body dries out, your mental processes can slow down. And the hotter the temperature, the more fluid you may lose (AIHAJ 2002; 63(2):190-8). B Vitamins for Energy Also important for keeping your energy up "is getting enough of the B vitamins and magnesium." And even though Dr. Teitelbaum advocates the necessity of a well-rounded multiple vitamin and mineral supplement plus an adequate diet and amino acids to get all the nutrients you need, he recommends "taking a high-level B complex. The RDAs (the government's Recommended Daily Amounts) are inadequate." In the body, B vitamins are used for the production of energy on a cellular level. For instance, vitamin B1 (thiamine) is crucial for burning carbohydrates effectively. And vitamin B6 (pyridoxine) is necessary for the body's ability to properly use B1. At the same time, vitamin B12 (cobalamin) is required for proper nerve function. The need for B12 may necessitate a supplement: Up to 30% of everyone over the age of 50 may have trouble absorbing B12 from their food (Crit Rev Clin Lab Sci 1996; 33:247). Plus, since vegetables contain very little absorbable B12, vegetarians of all ages may also require B12 supplements. Dr. Teitelbaum also believes that taking malic acid, a nutrient derived from apples, can help. Along with the B vitamins, malic acid is used by the body in the production of energy. When taken with magnesium, malic acid has been shown to ease the pain of fibromyalgia (J Rheum 1995; 22(5):953-7), a condition characterized by fatigue and lack of energy accompanied by painful muscles and joints. Ginseng Boost Asian ginseng (Panax ginseng) represents a potential tool for controlling blood sugar and improving stamina. According to Dr. Teitelbaum, "...Asian ginseng enhances energy, raises blood pressure and improves adrenal function...Asian ginseng has such a wide mix of health benefits that its name, Panax, comes from the Greek roots of pan (meaning 'all') and akos (meaning 'cure')-that is, 'cure all.'" Research on people with diabetes shows that this herb may help control blood sugar levels. People who suffer what is called type 2 diabetes often eat small meals to keep their blood sugar from varying too much. (Rising and falling blood sugar can drain you of energy as well as make diabetic problems worse.) An investigation of how another form of ginseng, American ginseng (Panax quinquefolius), affects blood sugar after eating found that it tempered changes by up to 20% (Arch of Internal Med 4/00). These scientists found that folks with diabetes did best when they took the herb within two hours of a meal. Ready to re-energize? Time to stop skimping on sleep and rushing through inadequate meals. For all of us, slowing down and giving our bodies a chance to regenerate its zip can make the big energy difference. -- Vitanet ® (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=351) Breast Cancer Date: June 10, 2005 09:44 PM Author: Darrell Miller (dm@vitanetonline.com) Subject: Breast Cancer Breast Cancer by Joseph L. Mayo,MD Mary Ann Mayo, MA Energy Times, May 2, 1999 What do you fear most? Bankruptcy? Floods? Heart disease? If you're like many women, breast cancer stands near the top of that dreaded list. But that fear doesn't permeate other cultures the way it does ours. A woman like Mariko Mori, for instance, 52 years old, Japanese, worries about intense pressures beginning to burden her toddler grandson. But worry about breast cancer? Hardly. In Indiana, Mary Lou Marks, 50, has similar family frets, mulling over her 28-year-old daughter's career choice. But on top of that, when Mary Lou tabulates her other worries, she recoils at the thought of breast cancer. She's heard about her lifetime risk: 1 in 8. Meanwhile, Mariko's is merely 1 in 40, according to Bob Arnot's Breast Cancer Prevention Diet (Little, Brown). American Problem Experts reporting in "Women at High Risk for Breast Cancer: A Primary Care Perspective" (Prim Care Update Ob/Gyns, vol. 5, no. 6, 1998, p. 269) say the risk of developing breast cancer for the average American woman during ages 40 to 59 is 3.9%; by 60 to 79 years of age that rises to 6.9%. A high-risk 40-year-old has a 20% chance of breast cancer in the next 20 years. New studies have found the effect of carrying the gene linked to breast cancer, which is responsible for only 5 to 10% of breast cancer incidence, is not as great as first suspected. Earlier estimates that the gene reflects an 80% chance of incurring breast cancer by age 70 has been recalculated to be only 37% (The Lancet, 1998;352:1337-1339). Complex Causesbr> Researchers agree: No one factor is solely responsible for breast cancer. Risk depends on many factors, including diet, weight, smoking, alcohol consumption, activity level and, of course, those genes. Regardless of their actual chance of getting breast cancer, women worry. Mary Lou faces no factors that would place her in particular jeopardy. But her anxieties about radical therapies and medical expenses paralyze her: She forgets to visit her health care provider and skips her annual mammogram appointments. Mary Lou's daughter, perhaps in reaction to her mother's gripping fears, campaigns ardently for cancer prevention, educating herself and mobilizing against the cumulative effects of known cancer risks. Smart young woman: A malignancy, after all, can take years to develop. A tumor must swell to one billion cells before it is detectable by a mammogram. Dietary Benefits Of all the tactics for reducing the risk of breast cancer, diet ranks high on the list. The soy-rich regimen of Japanese women like Mariko Mori, for example, helps to explain the low breast cancer rates in Asian countries (see box at center of the page). Tomatoes, because of their high quotient of the carotenoid lycopene, have been found to protect cells from the corrosive clutches of oxidants that have been linked with cancer in 57 out of 72 studies (The Santa Rosa Press Democrat, February 17, 1999, page A6, reporting on a Harvard Medical School study). For more on tomatoes see page 16. But there's no one magic anti-cancer food or diet. Eating to prevent breast cancer requires a balanced menu with fiber, healthy fats, phytoestrogens and antioxidants, all fresh and free of chemical additives. Modifying the balance and type of estrogen, the female sex hormone produced by the ovaries, offers an important breast cancer safeguard. Fat cells, adrenal glands and, before menopause, the ovaries, produce three "flavors" of estrogen, the strongest of which, estradiol, is believed to be carcinogenic when too plentiful or persistent in the body. Estrogen does its work by attaching to estrogen receptors. Receptors are particularly numerous in the epithelial cells that line milk sacs and ducts in the breasts. A receptor site is like a designated parking spot: Once estrogen is parked there it triggers one of its 400 functions in the body, from preparation of the uterus for pregnancy to intensifying nerve synapses in the brain. The food we eat can be a source of estrogen; plant estrogens, called phytoestrogens, are much weaker than the body's estrogens, but they fit the same receptors. Phytoestrogens exert a milder estrogenic effect than bodily estrogen and are capable of blocking the more potent, damaging versions. Finding Phytoestrogens Foods high in phytoestrogens include vegetables, soy, flaxseed and herbs such as black cohosh, chasteberry, red clover and turmeric. Soy is the darling of the day for good reason. Both soy and flaxseed can lengthen periods, reducing the body's overall exposure to estrogen. Soy also contains genistein, an "isoflavone" very similar in molecular form to estrogen but only 1/100,000 as potent. Because of its structure, genistein can attach to cells just as estrogen does; it also helps build carriers needed for binding estrogen and removing it from the body (Journal of Nutrition 125, no.3 [1995]:757S-770S). It acts as an antioxidant to counteract free radicals. Tumor Inhibition Studies have demonstrated that genistein inhibits angiogenesis (new tumor growth), slowing the progression of existing cancer. Soy is most protective for younger women. Postmenopausal women benefit from soy's ability to diminish hot flashes and for cardiovascular protection, especially in combination with vitamin E, fiber and carotene (Contemporary OB/GYN, September 1998, p57-58). Experts don't know that much about the cumulative effect of combining hormone replacement with soy, herbs and a diet high in phytoestrogens. Menopausal women who boost their estrogen this way should work with their health care providers and monitor their hormonal levels every six to 12 months with salivary testing. The Vegetable Cart Some vegetables are particularly protective against breast cancer because they change the way the body processes estrogen. Indol-3-carbinol, found in the co-called cruciferous vegetables such as cauliflower, broccoli and cabbage, diminishes the potency of estrogen. (Broccoli also contains isothiocyanates that trigger anti-carcinogenic enzymes.) These vegetables supply fiber, beta-carotene, vitamin C as well as other vitamins and minerals (Proc of the National Academy of Science USA, 89:2399-2403, 1992). Fiber from fruits, vegetables and whole grains reduces insulin levels and suppresses the appetite by making make us feel full, thus helping with weight control, so important to resisting cancer. Fiber also helps build estrogen carriers that keep unbound estrogen from being recirculated and reattached to the breast receptors. Cellulose, the fruit and vegetable fiber most binding with estrogen, also rounds up free radicals that damage DNA within cells.,p> Feeding the Immune System Despite heightened public awareness and efforts to stick to wholesome, healthful diets, experts increasingly link poor nutrition to depressed immune systems. Many Americans are at least marginally deficient in trace elements and vitamins despite their best attempts to eat well; that's why a good multivitamin/mineral is wise, even mandatory. Vitamins given to people undergoing cancer treatment stimulate greater response, fewer side effects, and increased survival (International Journal of Integrative Medicine, vol. 1, no. 1, January/February 1999). Nutrients tend to work synergistically on the immune system. They should be taken in balanced proportions, and in consultation with your health care provider. Immune Boosters In Research links low levels of calcium and vitamin D, an inhibitor of cell division and growth, to higher breast cancer rates. n Riboflavin (B2), pyridoxine (B6), pantothenic acid (B5), zinc and folate strengthen immunity. Selenium, in lab culture and animal studies, has helped kill tumors and protect normal tissues. n Beta-carotene and vitamins A, E and C are antioxidants. Vitamin C enhances vitamin E's effects, boosting immunity and protecting against cell damage. The antioxidant isoflavones in green tea, with soy, convey the anticancer effects of the Asian diet. Research shows actions that discourage tumors and gene mutations. The food you eat influences hormones. Excess sugar raises insulin, which acts as a growth factor for cancer and interferes with vitamin C's stimulation of white blood cells. It may contribute to obesity. Alcohol is converted to acetaldehyde, which causes cancer in laboratory animals. It affects gene regulation by decreasing the body's ability to use folic acid. It increases estrogen and the amount of free estradiol in the blood. The liver damage that accompanies high alcohol consumption frequently reduces its capacity to filter carcinogenic products, regulate hormones and break down estrogen. Studies of alcohol consumption have caused experts to estimate that drinking more than two alcoholic beverages a day increases breast cancer risk by 63% (OB-GYN News, November 1, 1998, p. 12). Fat Can be Phat Fat conveys nutritional benefits. Not all fats are bad: we can't survive for very long without certain fats. Fat can turn you into a "well-oiled" machine. But the wrong kind of fat (the fatty acids in red meats and fatty poultry) is believed to be a major culprit in breast cancer. Fat cells produce estrogen. Excess fat stores carcinogens and limits carriers that can move estrogen out of your system. Once estrogen has attached itself to a receptor, the health result depends on the type of fat in the breast. Saturated fat, transfatty acids and omega-6 fat from polyunsaturated vegetable oils such as safflower oil, peanut, soybean oil, corn oil and in margarine can increase the estrogen effect and trigger a powerful signal to the breast cell to replicate. Restraining Prostaglandins Blood rich in the essential fatty acids omega-3 and omega-9 lowers cancer risk by driving down levels of prostaglandins, which promote tumor growth. The blood and tumors of women with breast cancer usually contain high levels of prostaglandins. Breast tissue is protected by omega-3 fat chiefly from fish and flaxseed and by omega-9 from olive oil. Salmon once a week or water packed tuna three times a week are particularly beneficial. Fish oil supplements processed to reduce contaminates are available. Cod liver oil isn't recommended: its vitamin A and D levels are too high. Flaxseed is the richest known plant source of omega-3. Use a coffee grinder to benefit from the seed and oil for the full estrogen effect; sprinkle ground flaxseed over cereal or fold into baked goods. Drizzle flaxseed oil, found in the refrigerator section of your health food store, over salads or cereal. (Store the oil in the refrigerator.) Olive oil, especially in the context of the so-called Mediterranean diet of vegetables, omega-3-rich fish and fresh fruit (Menopause Management, January-February 1999, p. 16-19), lowers the risk of breast cancer (The Lancet, May 18, 1996;347:1351-1356). Selecting Organic Food Select organic foods for extra anticancer protection. Pesticides stimulate erratic cell action and often inhibit the estrogen carrier's ability to attach and remove estrogen from the body. Free floating estrogen then can attach to breast receptors and cause trouble. Buy or grow fresh, organic foods whenever you can. When grilling meat, fish or poultry, reduce the area where carcinogens may accumulate by trimming fat. Charred, well-done meat is known to be carcinogenic. When grilling, marinate meat first and reduce the cooking time on the grill by slightly precooking. Cancer prevention is an interlocking puzzle requiring the limitation of fat consumption, weight control, exercise, stress reduction and care for psychological and spiritual balance. Possessing more cancer fighting pieces makes you more likely to be able to complete the prevention picture. Joseph L. Mayo, MD, FACOG and Mary Ann Mayo, MA, are the authors of The Menopause manager: A Safe Path for a Natural Change, an individualized program for managing menopause. The book's advice, in easy-to-understand portions, isolates in-depth explanations with unbiased reviews of conventional and alternative choices. A unique perspective for mid-life women who want to know all their options. Also from the Mayos - The HOW Health Opportunities For Women quarterly newsletter to help women learn HOW to make informed health choices. Learn HOW to: - Choose nutritional supplements - Integrate natural remedies with conventional medicine. - Pick healthier foods. - Reduce breast cancer, osteoporosis and heart disease risk. - Slow aging's effects. Protect against environmental toxins. -- Vitanet ® (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=281) Higher Mind - Smart Nutrients for the Performance of a Lifetime... Date: June 02, 2005 12:18 PM Author: Darrell Miller (dm@vitanetonline.com) Subject: Higher Mind - Smart Nutrients for the Performance of a Lifetime... Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life. To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood. Brain Cells – Issued at Birth Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity. Brain Cell Membranes The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain. Phosphatidyl Serine – Key to Cognition For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4 The Chemistry of Thought Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn. Total Nutrition for the Brain The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain. The Importance of Magnesium Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral. B is for Brain Vitamins HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters. Brain Power Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings. For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime. References 1. Palmieri, G., et al. (1987). Clin. Trials J. 24: 73- 83. 2. Crook, T.H., et al. (1991). Neurol. 41: 644-49. 3. Nunzi, M.G., et al. In Phospholipids: Biochemical, Pharmaceutical and Analytical Considerations (ed. I. Hanin and G. Pepeu). New York: Plenum Press, 1990. 4. Heiss, W.D., et al. (1993). Annals N.Y. Acad. Sci. 695: 327-31. 5. Passeri, M., et al. (1990). Int. J. Clin. Pharm. Res. X(1/2): 75-79. 6. Kohjimoto, Y., et al. (1988). Japanese Journal of Pharmacology 48(3): 365-71. 7. Philpott, William H. Brain Allergies: the Psychonutrient Connection. New Canaan: Keats, 1987. 8. Passariello, N., et al. (1983). Int. J. Clin. Pharmacol. Ther. Toxicol. 21: 252-56. -- VitaNet ® VitaNet ® Staff (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=156) Heart Science - A Five-Tiered Approach to Heart Health ... Date: June 02, 2005 12:07 PM Author: Darrell Miller (dm@vitanetonline.com) Subject: Heart Science - A Five-Tiered Approach to Heart Health ... Heart Science 30 tabs Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available. Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for 1) generating energy, 2) decreasing harmful homocysteine levels, 3) fighting oxidized cholesterol, 4) maintaining the heart’s electrical rhythm, and 5) protecting artery and capillary linings. Energy Generators for An Energetic Organ Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply. There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently. CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10 Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound. Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21 HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells. Homocysteine Regulators B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization. The Dangers of Oxidized LDL Cholesterol While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL. When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse. The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes. Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol. Cholesterol Fighters Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits: • Beta Carotene, a plant pigment, is the naturally occurring precursor to Vitamin A. When the body takes in high enough amounts of Beta Carotene, this lipid-soluble free radical scavenger concentrates in circulating lipoproteins and atherosclerotic plaques, where it performs its antioxidant functions. Beta Carotene is particularly unique and powerful as an antioxidant because it is capable of trapping a very toxic form of di-oxygen, called singlet oxygen, which can result in severe tissue damage. Beta Carotene is one of the most efficient quenchers of singlet oxygen thus far discovered. Six tablets of HEART SCIENCE provide an unprecedented 45,000 IU of Beta Carotene! • Vitamin C is found in plasma, the watery component of blood, where it functions as a potent antioxidant. In addition to strengthening artery linings through collagen manufacture, Vitamin C is involved in the regeneration of Vitamin E within LDL particles. Vitamin C also plays an important role in the conversion of cholesterol into bile acids by the liver, a crucial step in reducing blood cholesterol levels. Once converted into bile acids, and then into bile salts, cholesterol can be excreted from the body, preventing build-up. Supplementation with Vitamin C may lower levels of LDL cholesterol and increase those of HDL cholesterol.25 It may also have a part in actually removing cholesterol deposits from artery walls — good news for people who are already experiencing plaque buildup.25 Each daily dose of HEART SCIENCE provides 1,500 mg of Vitamin C in its bioactive mineral ascorbate form. • Vitamin E, together with Beta Carotene, protects lipids from free radical attack. It is the major antioxidant vitamin that is carried in the lipid fraction of the LDL particle, where it protects the LDL particle from damaging oxidation. Within an LDL particle, one molecule of Vitamin E has the ability to protect about 200 molecules of polyunsaturated fatty acids from free radical damage! Vitamin E also aids in protecting the heart by interfering with the abnormal clumping of blood cell fragments, called platelets, within blood vessels.4 It has been shown to inhibit the formation of thromboxanes and increase the production of prostacyclins, which together decrease abnormal platelet aggregation.11 A high potency of Vitamin E — 400 IU’s — is included in six tablets of HEART SCIENCE in the natural d-alpha succinate form, recognized by scientific researchers to be the most absorbable form! • Selenium is an important mineral which has only recently gained attention. When incorporated into the enzyme Glutathione Peroxidase, it has highly powerful free radical-scavenging abilities, and has been shown to work synergistically with Vitamins A, C, and E. An essential mineral, Selenium used to be derived from eating foods grown in Selenium-rich soil. However, modern agricultural practices have depleted soil of its natural Selenium content, leaving many Americans deficient in this vital nutrient. Several epidemiological studies show that the incidence of advanced fatty deposits in blood vessels is much greater in individuals living in geographic areas of the United States and other parts of the world where the Selenium content of the soil is very low.27 • Proanthodyn,™ an extract of grape seeds, is being called the most powerful antioxidant yet discovered. This highly potent, water-soluble bioflavonoid contains between 93-95% proanthocyanidins, the highest concentration of any nutrient available today. The protective actions of proanthocyanidins may help to prevent the development of plaque in artery walls by inhibiting the free radicals which are produced during the oxidation of cholesterol. The optimal daily amount (100 mg) of Proanthodyn is included in six tablets of HEART SCIENCE. In addition to the protective actions of antioxidants, several other nutrients can contribute to healthier cholesterol ratios. • Chromium is a trace mineral which functions to aid the entrance of glucose into cells. Six tablets of HEART SCIENCE provide 300 mcg of Chromium in the form of Chromate® Chromium Polynicotinate and Chromium Picolinate — the most bioactive forms of Chromium. Not many people are familiar with the vital role Copper plays in the body. This trace mineral is found in all tissues of the body, and is particularly concentrated in the heart. Copper is part of several enzymes, and, in this capacity, is necessary for the development and maintenance of the cardiovascular system, including the heart, arteries, and other blood vessels. Because of its role in elastin production, Copper deficiency can severely damage blood vessels and heart tissue. In fact, researchers have found an inverse relationship between Copper status and increased risk for heart damage.10 • L-Proline and L-Lysine are two natural amino acids which show exciting promise in helping to prevent fatty deposits in blood vessels. Researchers have recently identified a particle associated with LDL called apoprotein (a) which is believed to be a main culprit in plaque development. 17 Scientific investigation has revealed that the lipoprotein (a) particle has an adhesive quality that makes the lipoprotein fat globule stick inside blood vessels. The sticky fat globules accumulate, leading to fatty deposits in blood vessels and the subsequent clogging of the arteries. L-Proline and L-Lysine tend to form a barrierlike layer around the apoprotein (a) particle, helping to push it away from the blood vessel wall, and impeding deposit.21 The Regulating Trio Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings. • Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells. Artery Lining Protectors Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6 Capillary Strengtheners Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart. Heart Smarts The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care. Source Naturals HEART SCIENCE™ The Five Tiered Approach to Heart Health Six tablets contain: Vitamins and Minerals %USRDA Pro-Vit A (Beta Carotene) 45,000 IU 900% Vit B1 (Thiamine) 50 mg 3333% Vit B3 (Inositol Hexanicotinate) 500 mg 2500% Vit B6 (pyridoxine HCl) 25 mg 1250% Coenzyme B6 (Pyridoxal-5-Phosphate) 25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%) Vit B12 (Cyanocobalamin) 500 mcg 8333% Folic Acid 800 mcg 200% Vit C (Magnesium Ascorbate) 1500 mg 2500% Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333% Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg * Copper (Sebacate) 750 mcg 37.5% Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75% Potassium (Citrate) 99 mg * Selenium (L-Selenomethionine) 200 mcg * Silicon (From 400 mg of Horsetail Extract) 13mg * * U.S. RDA not established. Other Ingredients and Herbs Coenzyme Q10 (Ubiquinone) 60 mg L-Carnitine (L-Tartrate) 500 mg Hawthorn Berry Extract 400 mg Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg L-Proline 500 mg L-Lysine (HCl) 500 mg NAG™ (N-Acetyl Glucosamine) 500 mg Bromelain (2000 G.D.U. per gram) 1200 G.D.U. Taurine (Magnesium Taurinate) 500 mg Horsetail Extract (Yielding 31 mg of Silica) 400 mg Inositol (Hexanicotinate) 50 mg Reference: 1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9. 2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240. 3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077. 4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61. 5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402. 6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33. 7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5. 8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81. 9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45. 10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside. 11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404. 12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8. 13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9. 14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601. 15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251. 16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764. 17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18. 18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93. 19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425. 20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45. 21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now. 22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4. 23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456. 24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291. 25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America. 26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881. 27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42. 28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company. 29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88. 30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185. 31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc. 32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403. 33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company. 34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing. 35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8. -- VitaNet ® VitaNet ® Staff (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=155) GlucosaMend™ Tissue/Joint Repair Complex Date: June 02, 2005 11:19 AM Author: Darrell Miller (dm@vitanetonline.com) Subject: GlucosaMend™ Tissue/Joint Repair Complex GlucosaMend More than 40 million Americans experience joint discomfort. But exciting new research proves you can do something about it. Our health and well-being is inextricably linked to lifestyle choices: the right combination of exercise, weight training and supplementation can strengthen muscles and joint tissues to minimize stress and degradation. Targeted nutrition to the multiple body systems related to joint and connective tissue can help maintain flexibility and joint comfort. GLUCOSAMEND supports the musculoskeletal system with structural building blocks and tissue production cofactors, as well as aiding the body’s mechanisms for soothing relief and antioxidant defense. Bio-Aligned Formula™ GLUCOSAMEND is uniquely effective because it is a Bio-Aligned Formula. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance. Musculoskeletal System—Structural Building Blocks Certain building blocks of joints and connective tissue can help maintain joint integrity and comfort. Glucosamine is a major constituent of glycosaminoglycans, which in turn form proteoglycans, molecules that hold and bind the water that lubricates joints, disperses stress and nourishes joint tissue. The amino acids proline and lysine are structural components of collagen and elastin, which give strength to connective tissue. GLUCOSAMEND contains glucosamine sulfate, N-acetyl glucosamine, proline and lysine. Musculoskeletal System—Tissue Production Cofactors Some micronutrients are necessary as cofactors in the production of connective tissue. For example, vitamin C and copper help form hydroxyproline and hydroxylysine, main constituents of collagen. A unique property of grape seed extract is its ability to form a bond between broken collagen fibers, helping to repair them and restore flexibility and strength to connective tissues and joints. GLUCOSAMEND provides vitamin C, zinc, manganese, copper, and grape seed extract to address these cofactors. Soothing Relief Mechanisms Some herbs and nutrients have the capacity to support the body’s natural mechanisms for increasing comfort. Boswellia, for example, is an herb with soothing properties, while vitamin B-6 helps to stabilize collagen and elastin. Additional herbs and nutrients, acting in conjunction with antioxidant protectors, support tissue comfort and health. GLUCOSAMEND contains Boswellia serrata, quercetin, copper, and vitamin B-6. Antioxidant Defense The health and integrity of joints and tissues—specifically of cell membranes— is supported by botanicals and nutrients that support the body’s natural antioxidant response. When tissues become damaged, the body mounts a repair process that ultimately generates free radicals. These free radicals can also break down healthy cells and tissues in the process, hence the need for antioxidants to neutralize and break the cycle. GLUCOSAMEND provides grape seed extract, vitamin C, zinc, selenium, copper, quercetin to neutralize free radicals. Lifestyle Tips for Healthy Joints: A Strategy for WellnessSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Source Naturals believes in a holistic approach to living. Not only can supplements bring balances to your individual body systems but certain lifestyle choices can also bio-align your health. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, limit saturated fat and eliminate hydrogenated oils. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAME, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CHONDROITIN to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage. Structural Building Blocks N-Acetyl Glucosamine, Glucosamine Sulfate, L-Lysine, L-Proline Tissue Production Cofactors Grape Seed, Copper, Manganese, Zinc, Vitamins A, B-6 and C, Niacinamide Soothing Relief Mechanisms Boswellia Serrata, Quercetin, Turmeric, Copper, Magnesium, Zinc, Vitamin C Antioxidant Defense Grape Seed, Quercetin, Manganese, Selenium, Zinc, Vitamins A, C and E References Bhavan’s, B. H. Selected Medicinal Plants of India (A Monograph of Identity, Safety, and Clinical Usage) Bombay: Chemexcil, 1992. Dore-Duffy, P., et al. (1990, Nov-Dec.). “Zinc profiles...” Clinical and Experimental Rheumatology 8.6: 541-46. Ellis, J. M. (1985, Winter). “Vitamin B6 deficiency and rheumatism.” Anabolism. Lakshmi, R., et al. (1991, Oct-Dec.). “Effect of riboflavin or pyridoxine deficiency on inflammatory response.” Indian Journal of Biochemistry and Biophysics 28.5-6: 481-84. Leibovitz, B., (1991). Nutrition Update 5.3: 5. Levine, M. (1986). “New concepts in the biology and biochemistry of ascorbic acid.” New England Journal of Medicine 314: 892-902. Pavelka, K, Gatterova, J., Olejarova, M, Machacek, S., Giacovelli, G., Rovati, L.C., (2002). “Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis: A 3-Year, Randomized, Placebo-Controlled, Double-Blind Study. Arch Intern Med, 2002 October 14; 162(18):2113-23. Roubenoff, R., et al. (1995, Jan.). “Abnormal vitamin B6 status...” Arthritis and Rheumatism 38.1: 105-9. Shampe, P., and R. Harvey. Lippincotts Illustrated Reviews: Biochemistry. Philadelphia: J. B. Lippincott Company, 1987. Tarp, U., et al. (1985). Scandanavian Journal of Rheumatology 14.2: 97-101. Volpi, N., (2002). “Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers,” 2002 Oct; 10(10):768. -- VitaNet ® VitaNet ® Staff (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=152)

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