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Curcumin stops cancer cell growth, NEW scientific discovery   
Date:
April 27, 2019 10:10 AM
Turmeric is hailed for its properties in helping to regulate blood sugar, fighting inflammation and infection, and helping cancer patients. In helping cancer patients, turmeric is able to affect cancerous cells without harming the non-cancerous cells. DYRK2 is inhibited by the turmeric, keeping the cancer from growing. Carfilzomib used with turmeric helped with cancer cell death with minimal affect to the healthy cells. Turmeric also promotes angiogenesis, which stops the growth of new blood vessels which support the growth of tumors, and also doesn't allow development of adhesion which leads to metastasizing of cancers. Key Takeaways:
"The team used cutting-edge X-ray crystallography to obtain 3D images – in which curcumin could distinctly be seen binding to the enzyme at the atomic level." Read more: https://www.naturalhealth365.com/curcumin-cancer-cell-2659.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6206) Calcium is essential 
Date:
December 02, 2016 12:59 PM
You probably know that calcium is good for you. But in reality, you’re probably murky on the details as to why it’s so important, and like many people, you may not be getting enough calcium in your diet. Bones provide a mineral reservoir to buffer the blood levels of calcium, to keep it in a narrow range, for optimal neural and muscular function. Muscle contraction is initiated by calcium binding to signal the action. Key Takeaways:
"Calcium is a hard, silvery metallic element with an atomic number of 20 and an atomic weight of 40.078. It is a mineral found in bones, teeth and other body tissues." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3553) What Is Artemisinin?
Date:
April 28, 2014 06:56 PM
Long known as an imposing enemy to malaria and other significant parasites, studies indicate that Artemisinin could assume a useful part in cancer medicines. Uncovered to be a compelling malaria medication many years prior by Chinese botanists, the most recent century has seen that artemisinin is utilized productively within western pharmaceutical. Not just artemisinin treat the worldwide executioner malaria, yet late studies are additionally revealing to its medicinal viability extending from malaria to cancer. It's exceptionally extraordinary in its sub-atomic structure in that it has two oxygen particles joined together by what's known as an 'endoperoxide span'. Why Artemisinin utilization are so wide is unequivocally on account of this extension and its unique atomic structure. Its piece implies it responds with particles with a high iron substance, for example, malaria parasites and cancerous tumors. Upon contact with infected cells (with this high iron substance), its system of activity is to structure free radicals. These free radicals are poisonous to the respectability of the attacking cells, separating them and in the end leaving the contaminated cells devastated.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3107) What Is Vanadyl Sulfate And How Does It Relate to Diabetes?
Date:
December 22, 2011 09:24 PM
What is Vanadyl SulfateVanadyl Sulfate This is a well known inorganic compound of vanadium and in some circles it has been commonly referred to as another name for vanadium. This water soluble sulphate is known to be the most stable diatomic ion in the scientific world and has been known in the medical industry as something that has the same effect as insulin. It basically is a metallic element and is a soft and ductile element which is physically described as silvery white in colour and when it is in powder form it looks as if it is light gray. History and Discovery It is commonly known that this metallic element was discovered by a Spanish professor named Andres Del Rio who in 1801 was able to find the element erythronium in Mexico however at the time Professor Del Rio felt it was nothing new so he did not pursue to prove it any further and this is when a Swedish Chemist named Nils Gabriel Sefstrom got the credit for its discovery and it remained as the more known fact until a German Chemist by the name of Friedrich Wohler was able to prove otherwise in 1831. He was able to prove that both discoveries were the same. Uses and Functions The main belief in the medical world and as proven is that it is able to function like insulin and it is able to mimic insulin’s effects to the body. As such you might have guessed what follows. It is able to help with diabetes because various studies suggest that it is able to lower the blood sugar levels in the body which is exactly what the purpose of insulin is especially when it is in high doses. Other studies also has confirmed that it also can possibly help with conditions like heart disease and high cholesterol which are diseases that diabetes usually affect as well although further studies needs to be done to this respect. Safety and possible side effects Vanadium has been shown to be safe for use by adults although it needs to be a fairly low dose unlike the one that is needed for diabetes. Possible side effect ranges from diarrhea to nausea and some abdominal discomfort. Furthermore, it is safe to say that this should not be taken by breast feeding women as it may have undesired side effects.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2550) Fight Infertility
Date:
April 01, 2009 05:35 PM
Infertility is typically defined as a failure to conceive after a year or more of regular intimate activity during the time of ovulation. This term can also refer to the inability to carry a pregnancy to term. About 6.1 million American couples are impaired when it comes to their ability to have children, with 2.1 million of these couples being infertile. The exact cause of the problem can be extremely difficult to pinpoint, as ovulation, fertilization, and the passage to the fertilized ovum through the fallopian tube and to the uterus are extremely complex processes. In order for pregnancy to occur, many events must work together perfectly. In 40 percent of infertile couples, problems that affect the male partner are either partially or wholly the cause of infertility. Infertility in men is usually the result of a low sperm count or an anatomical abnormality. There are a variety of factors that can result in a low sperm count. Among these factors are alcohol consumption, endocrine disorders, exposure to toxins, radiation or excessive heat, recent acute illness or prolonged fever, testicular injury, and rarely, mumps-induced wasting of the testicles. An abnormal enlargement of veins that drain the testicles, referred to as varicoceles, can cause infertility in men. This is because the veins of the testes are no longer able to moderate the temperature of the testicles correctly, which can negatively affect sperm. The most common causes of infertility in women include an ovulatory failure or defect, blocked fallopian tubes, endometriosis, and uterine fibroids. Additionally, some women are able to develop antibodies to their partners’ sperm, which causes the woman to almost be allergic to them. Chlamydia, a transmitted disease which affects 4 million Americans each year, also causes many cases of infertility. There are also psychological issues, such as stress or fear of parenthood, which can also contribute to infertility. However, in most cases, stress is usually the result of infertility, not the cause of it. Sperm abnormalities account for about 41 percent of infertility cases. The following reasons are the most common to explain why couples cannot conceive: the woman has endometriosis; the man has abnormal sperm, a low sperm count, or erectile dysfunction; the woman’s fallopian tubes are blocked; ovulation takes place rarely or irregularly; the couple is unable to have complete intimate relations; the cervical mucous attacks and kills the sperm; the woman does not manufacture enough progesterone to carry a baby to term; the woman is over thirty-four; and/or one or both members of the couple eats a poor diet and experiences too much stress. The following nutrients are extremely beneficial in helping one or both partners deal with infertility: selenium, vitamin C with bioflavonoids, vitamin E, zinc, DMG, octacosanol, phosphatidyl choline, essential fatty acids, l-arginine, manganese, proteolytic enzymes, pycnogenol, raw orchic glandular, raw ovarian glandular, 7-keto DHEA, vitamin A, and vitamin B complex. Also, the following herbs have been shown to be beneficial in dealing with infertility: astragalus, damiana, ginseng, sarsaparilla, saw palmetto, yohimbe, dong quai, false unicorn root, gotu kola, licorice root, wild yam root, green oat, and yin-yang-huo. It should also be noted that heavy use of Echinacea, ginkgo biloba, and St. John’s wort may cause infertility in men, and should be avoided. Infertility can be a complicated and mentally depressing due to lack of pregnancy by both men and women. Depression can lead to more stress and needs managed by a health care provider. Always consult your doctor when you think you are infertile. Natural vitamins like the ones listed above are available at your local or internet health food store. Look for name brands vitamins to ensure you receive quality supplements. *Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1985) Activated Charcoal - Highly absorbent material to combat poisoning
Date:
April 24, 2008 02:44 PM
Activated charcoal has been treated by heat to open up millions of small spaces between the carbon atoms and turn it literally into an atomic sponge that adsorbs both organic and organic impurities. This heat treatment is carried out in the absence of oxygen, so the charcoal cannot burn. Instead, what oxygen it did contain is driven off leaving behind all of these interstitial gaps that multiply the effective surface area by factors of ten. Since it is the surface area of the charcoal that determines its potency, then the greater this is the better. Activated charcoal has a massive surface area, and just ten grams has the same surface area as nine American football pitches or 77 tennis courts. Ten grams is just marginally more than a third of an ounce. The term adsorb has a different meaning to absorb, and while a real sponge absorbs water by mopping it up through capillary action and suction, activation carbon adsorbs substances through a form of chemical attraction. You get rid of water from the sponge by squeezing it, but that doesn’t work with activated charcoal, since the substances are bound to it, not just physically constrained. This huge surface area provides activated charcoal with innumerable bonding sites, and when chemicals that are attracted to carbon pass by they are attached to the surface. They cannot get free again, as water in a sponge can, but are bound to the surface of the carbon. Because the digestive system has no effect on charcoal then whatever is bound to it passes naturally through the body. It is most effective at binding other carbon-based materials, and other substances with the right electronic arrangement, but others will just pass straight through. Because it is a chemical process, once all of the empty bonding sites have been taken up, the charcoal loses its effectiveness and has to be replaced. It is possible to regenerate it, but hardly worthwhile for you to do so because of the small quantities you use. Because of the way it works, activated charcoal can help people to recover from some forms of food poisoning. It can adsorb gases in the intestine and help to relieve the pain of excessive gas in the gut. It has many additional uses that will be touched on later, but for now we will look at its effect on poisons because that is where activated charcoal is of greatest benefit to us. It does not adsorb and neutralize all poisons, but is very effective with those that it can be sued for. Professor Touery proved a point when he drank a lethal dose of strychnine in front of colleagues at the French Academy of Medicine in 1831 and came through unscathed. He had mixed the strychnine with activated charcoal, and the fact that he lived after drinking a dose that would certainly have led to a very painful death within minutes testifies to the powerful effect of activated charcoal as an potential antidote for poisoning. Ever medicine cabinet should have an emergency supply of activated carbon, especially those with young children in the household. However, this is not good news for the pharmaceutical companies who have reacted by refuting some of the claims made in its favor: they have claimed that it is not effective against arsenic. If that is so, then how did Michel Bertrand survive after swallowing 5 grams of arsenic trioxide – 150 times what is regarded as the lethal dose? He did this is 1813 after mixing it with activated charcoal, just as Professor Touery was to do 18 years later with ten times the lethal dose of strychnine. It is true, however, that it does not have this degree of activity with all poisons, and it has no effect on cyanide, alcohols, antifreeze (glycols) and lithium. It also has no effect on corrosive poisons such as the strong alkalis used in oven clearers, or hydrocarbons such as kerosene. The way it works is adsorb the poison and prevent it being released into the body. For that to happen, the poison must have an affinity for carbon, and its adsorption site, and not all substances possess that property. Those that do however are permanently bound and therefore safe. For charcoal to be effective in neutralizing a poison, it must be swallowed within an hour of taking the poison, or the poison will be too far advanced ion the digestive process for the charcoal to do any good. Keep in mind, though, that it is not selective, and activated charcoal can adsorb nutrients and other beneficial constituents of your body’s chemistry. It is important therefore that you take in only when necessary: you might need several doses if the poison was severe, but once it has done its job it is not meant to be used as a maintenance material to take ‘just in case’. Used like that, it can do harm. If charcoal can adsorb poisons then it makes sense to believe that it can also adsorb some of the harmful agents that cause food poisoning. Not all food poisoning of course, but certainly those organisms that emit toxins that are attracted to carbon. And this is, in fact, the case. Food poisoning is caused by bacteria rather than viruses, and is not the presence of the bacteria that make you vomit and feel very ill. As bacteria grow in your body they release toxins, or poisons, into your digestive system. These poisons are what make you ill. They can seriously affect the complete gastro-intestinal tract, causing vomiting, diarrhea, and inflammation and swelling of the small and large intestine. The latter can cause abdominal cramps and severe colic, and the severity of the symptoms depends very much upon the type of bacteria and the number of them in your body. Many of these toxins are attracted to carbon since they are frequently organic based, and activated charcoal can be used to adsorb them. Once adsorbed they lose their potency, and since carbon is not digested by the body, they are passed harmlessly through the colon and eliminated in the faeces. It can also be used to eliminate many other foreign bodies from your gut, including viruses and fungi and might possibly reduce the concentration of uric acid, which can bring relief to gout sufferers. Activated charcoal has many uses, and is normally available in capsule form. It can be dangerous to take too much, particularly if you suffer from intestinal problems that cause constipation, because the charcoal itself can have that effect. However, there is no better emergency treatment for accidental poisoning in the home, although, since it is not suitable for all poisons, you must still regard poisoning as an emergency and contact the emergency services.
Activated charcoal, or activated carbon as it is sometimes called, is also a good emergency treatment for vomiting and the other unpleasant effects of food poisoning. It deals with bacterial toxins in the same way as any other, though once again you must refer to your physician before or after using it – preferably the former.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1769) Acai: The Super Antioxidant From Brazil
Date:
February 03, 2008 02:07 PM
Acai is an Amazonian palm tree, and possesses small purple fruits that the Amazonian natives of Brazil have used since time immemorial as food and as a remedy for certain health conditions that are now known to be associated with the activity on free radicals on body cells. The active constituents of acai are powerful polyphenols and anthocyanin antioxidants that protect your body cells from oxidation by free radicals. In fact the plant has been referred to as ‘the super antioxidant from Brazil’ by many medical writers who have recognized its right to be termed as such. To understand that, you first have to understand what an antioxidant is and how it works. The chemical names of the active substances it contains will be meaningless without that background knowledge. Oxidation occurs in your body even before you are born. What is does in general terms is to destroy your body cells, and the more it progresses the more your body is prone to cancers and cardiovascular diseases, and the more visible becomes the aging process. Chemically, oxidation is the loss of one or more electrons by an atom or molecule. Oxidation within your body is highly associated with what are known as free radicals. To explain these we have to consider the chemistry of electron pairs and free radicals, though this is not too technical so read on. Normally electrons exist in pairs of opposite spin: in simple terms each pair makes up a single negative charge. Take hydrogen: its atomic structure contains one proton and one electron. However, the hydrogen atom cannot exist by itself since the most stable configuration is that electrons exist in pairs with a net zero spin, so the hydrogen molecule consists of two hydrogen atoms with their own protons sharing an electron pair. This is true of all covalently bonded molecules. However, certain influences, such as pollution through tobacco smoke, pesticides, engine exhausts and the excess UV radiation of sunlight can cause a molecule to lose an electron. This creates what is known as a free radical: a molecule without an electrical charge but with an unpaired electron. Since the most stable configuration for it is to have a paired electron, the molecule will steal an electron from the most suitable candidate it finds. In practise this will be a body cell, and the cell that loses the electron gets destroyed causing aging of the skin and many other undesirable effects, including cancers. This stealing of an electron is chemically referred to as oxidation. Antioxidants prevent this occurring to your body cells by being reactive themselves and preferentially mopping up these free electrons. Polyphenols and anthocyanins are powerful antioxidants, and that is why the people of the Amazon rainforests have used acai not only as a food, but also for their health. It is only relatively recently that, as with many of the ancient health remedies, the scientific basis behind its use has been proved. The early Brazilian natives may not have understood biochemistry or what free radicals were, but they sure knew what was good for them. As with many other foodstuffs containing powerful antioxidants, it is likely that it was the highly colored berries that first attracted them. That does not suggest that all brightly colored foods are good for you, but the brightly colored pigments and dyestuffs contained within them also tend to act as antioxidants due the same electron configuration that provides them with their color. Many of these chemicals are also use as food dyes, and have been used so since before their chemistry and antioxidant effects were known. The color comes from the same electron activity that makes them destroy free radicals. That is why most highly colored foods contain significant quantities of phytochemicals. The deep purple color of the acai fruit led chemists to determine its content of polyphenols, such as anthocyanins, that are common in other highly colored foods such blueberries, peppers and aubergines. High concentrations of anthocyanins such as cyandin-3-glucoside and the rutinoside analogue were found, together with flavonoids such as orientin, deoxyhexose and scoparin. A total of twelve flavonoids were discovered that explains the highly antioxidant properties of the fruits. Laboratory and other tests have indicated that over 80% of the antioxidant effect of acai is due to polyphenols other than the anthocyanins. It is likely that these are the twelve flavonoids identified to date and any others that have still to be detected. However, it is not only for its antioxidant properties that acai is such a healthy fruit, since it contains many other nutritional components. It contains fatty acids, including linoleic acid, an omega-6 fatty acid and also beta-sitosterol that are believed to reduce the level of LDL cholesterol in the blood. The fruit also contains a high level of amino acids, essential for the synthesis of proteins and DNA. So what exactly does this mean for you in real terms? Antioxidants can do different things for different people, and the acai berry is said to have more than thirty times the antioxidant power of red wine. When you consider that many doctors believe one glass of red wine to provide sufficient antioxidant for the average person, you are getting a very high dose with acai berries, so what does it do for you? Due its effect in destroying the free radicals caused by pollution, acai and similar powerful sources of antioxidants are becoming increasingly important to our diets. What was a sufficient antioxidant intake even twenty years ago is not longer sufficient. Acai can help to combat early aging by reducing the rate at which your body cells are destroyed by free radicals. It also reduces the risk of cardiovascular disease, and the associated high risk of strokes or heart attacks. Acai juice itself has an unusually high fiber content, and helps maintain the health of your digestive system. An associated benefit of this is that you are less liable to contract colon cancer than if you did not consume it. Due to a reduction in the rate of destruction of body cells, including brain cells, elderly people benefit through maintenance of their brain function, and a lower likelihood of degenerating cognitive ability. It helps you to maintain concentration and memory, and can also reduce the risk of you getting cataracts. Antioxidants are also known to help maintain the immune system, and act as anti-inflammatories, and it is believed that acai juice can help to reduce the symptoms of arthritis. If you use acai berries as part of a daily diet, you should receive the benefits that it provides, although a more measured dosage in the form of a supplement will enable you to control your intake of acai, and if one thing is certain it is that you will be far healthy with a regular dose of the superantioxidant from Brazil than without.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1712) Looking For A Calcium But Not Sure Which Is Best For You?
Date:
November 02, 2007 12:23 PM
Calcium is essential to good health, but if you are looking for calcium it can be confusing to decide in which form you take it. There are so many available and every one claims to be good for you, so why the difference? Why not just sell the best and let us all know what it is? Well, this same argument could be applied to all supplements that are sold in different forms, and also to many foodstuffs. The supplement best for you might not be the best for the next person due to dietary requirements each persons diet is different, so it is better to learn about what is available then make your choice based upon knowledge rather than ignorance. It is not only the source of the calcium you have to bother about, but also the other vitamins that have be present to make sure that that the calcium is absorbed by the body in the way that you want it to be. To understand that then you need to learn why the body needs calcium, other than just the bones and teeth that everybody knows about. After all, why else do we need calcium? It is only contained in bones and teeth – right? Wrong! Although 99% of calcium is contained in your bones and teeth, 1% is contained in the blood, muscles and central nervous system. With out that 1% we would all die. Without teeth we would not. Calcium is essential for blood clotting and for the proper function of our muscles, brain and central nervous system. Calcium combines with phosphorus to create healthy bones and teeth, and is essential early in life to build up a strong skeleton. Note that phosphorus is also necessary so we also need an adequate supply of that mineral. Calcium is essential to allow muscles to properly contract. Without that ability, muscles could not work, and a deficiency of calcium causes muscle cramps and spasms. The movement of the smooth muscles is regulated by a protein that is bound to calcium. This is just one of the uses of the calcium in the body that most people are unaware of. Calcium also takes part in the binding process of the blood platelets during the coagulation of blood. Although most people are aware of the need for vitamin K and fibrin, in fact calcium is also essential in its interaction with the platelets in the coagulation cascade that eventually results in a blood clot that stops bleeding. Basically, without calcium, the blood could not form a clot. In addition to its effect on blood clotting, calcium also plays an essential part in the movement of ions through the membranes of nerve cells, and without it intercellular communication could not occur. Our nerve impulses would not occur and the body again would not be in a working condition. However, the body has a way of modulating the calcium level in the blood past a minimum level needed for effective nerve cell communication, and below a certain level it can even use the calcium in the bones to divert to the more needy areas of the body. It is therefore not possible for the body to fail through a lack of calcium. The skeleton would disintegrate first. Nevertheless, nobody wants a disintegrating skeleton since that would be counterproductive to effective movement of the body, so a good source of calcium is essential for overall bodily health, not just that of the teeth and the bones. There are many sources of calcium, but some are more suitable for absorption by the body than others. Chalk, or calcium carbonate, is an excellent source of calcium, but will fail to promote bone growth if your diet does not contain sufficient potassium, vitamin D, magnesium and strontium needed to make it work to build healthy bones. It is the most common on the shelves, and likely the cheapest, but not necessarily the best source. It is basically chalk or limestone, and only 10% of the supplement will actually become available for your body to use. The bioavailability of a calcium supplement is a figure that indicates how much of the calcium is actually absorbed by the body during digestion. It is important that the supplement is digested and absorbed properly or the calcium will not be available for use. This availability is called the ‘bioavailability’. Calcium citrate has a bioavailabilty of 50%, but the size of the citrate part of the molecule is so large that only 10.5% of the molecule is available to the body as calcium. Not much more than the carbonate. Calcium aspartate is highly soluble and produced by reacting calcium with aspartic acid to form the soluble salt. It is much easier to assimilate and be absorbed by the body than any of the forms above. The amino acid, aspartic acid, delivers the calcium exactly to where it is needed, where it is absorbed and used. Although a bioavailability figure is not available, it is not the amount of calcium that is significant here but the fact that it comes with its own transportation system and is immediately available where needed. If you want to calculate the availability for yourself, find the molecular weight of the particular calcium product, and then the weight of the calcium contained within it. For example, in calcium carbonate, CaCO3, the molecular weight is 100 (40 + 12 + 3x16) and the atomic weigh of calcium is 40, so the amount of calcium present in 1000g calcium carbonate is 40% or 400g. Only 25% of calcium carbonate is absorbed, so only 10%, or 100g, of calcium is available for each 1000g supplement. Calcium citrate on the hand (Ca3(C6H5O7)2.4H2O) has a molecular weight of 570, so the amount of calcium present is 3*40*100/570 = 21%. Since the bioavailability of calcium citrate is 50%, the amount of calcium available is only 10.5%, or 105g in 1000g citrate. You can carry out the same calculation on all the molecules if you know how much is absorbed by the body. The bioavailability is calcium aspartate is 85%. Its molecular formula is [C4H6NO2]2Ca, and molecular weight 304. The calcium availability is therefore 40*100/304 = 13.16%. If 85% is absorbed, then 1000g provides 80% of 13.16 x 10 = 115.6g. The aspartate therefore wins it. Amino acid chelates can also be used as a source of calcium, and its bioavailability is improved tremendously by including vitamin D and magnesium in the supplement. The bioavailability of these calcium chelates are not quoted, but is claimed to be high. Whether or not it is as high as the aspartame is debatable, though it is claimed to be. Calcium is a very important mineral for human health, and there are several different supplements that can be used. The bioavailability of the calcium is different in each supplement, though the organic forms, calcium aspartate and amino acid calcium chelates appear to be the highest. When looking for a calcium supplement look for one with additional minerals added as mentioned above to help improve absorption and usability by the body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1612) Neurological Health and CoQ10
Date:
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases. Q. What is CoQ10? A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body. Q. Isn’t CoQ10 a supplement for heart health? A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage. Q. How does CoQ10 affect brain health? A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production. The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced. The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced. Q. What is the blood-brain barrier and why is it important? A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree. Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle. Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier. Q. If CoQ10 is made in the body, why take supplements? A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body. Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10. Q. How does CoQ10 help people with Parkinson’s disease? A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration. A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment. Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months. The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10. The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease. Q. What were the results of clinical research on Huntington’s Disease? A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease. Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness. Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10. Q. What other diseases could benefit from CoQ10 supplementation? A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s. In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health. ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation. Q. Can taking CoQ10 prevent neurodegenerative disease? A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases. Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection. Q. How much CoQ10 should I take? A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day. CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect. Q. What should I look for in a CoQ10 supplement? A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor. Conclusion CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body. All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1459) HIGH STANDARDS AND ATTENTION TO DETAIL
Date:
December 27, 2005 09:05 AM
HIGH STANDARDS AND ATTENTION TO DETAILNOW’s state-of-the-art analytical laboratory boasts some of the most accurate and efficient chemical analysis equipment currently available. In addition to the equipment detailed at right, NOW scientists also utilize Atomic Absorption Spectroscopy, which allows us to accurately identify and analyze minerals and trace elements. All of these machines significantly contribute to our high product quality standards.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1083) Source Naturals - Continuous Quality Assurance
Date:
August 20, 2005 11:44 AM
“I oversee all the inspections, tests, and document reviews performed by our dedicated Quality Control staff to ensure that nothing compromises the healthfulness and high quality of our products.” Norm Nelson, Ph.D., Quality Control Director Continuous Quality Assurance Our Quality Control Department includes staff trained in microbiological assays, heavy metal screening, analytical chemistry and Eastern and Western herbalism. They utilize procedures that go beyond minimum industry requirements to ensure product excellence. All raw materials and finished goods must meet our inspectors’ rigorous quality specifications at every stage of manufacturing. Pure Raw Materials Bulk raw materials must be accompanied by Certificates of Analysis provided by the vendors. They are sampled and inspected according to a long list of specifications, including appearance, color, odor, flavor, texture, absence of extraneous material, and potency of active constituents. Vitamins, minerals and amino acids are screened and/or tested for impurities, while materials, such as herbs, that are biological in origin are tested for microbiological contamination. Bioavailable Manufactured Product Inspectors scrutinize finished tablets to see that they meet our standards for consistency in size, color, aroma or taste, are not broken, and contain no contaminants. Representative samples are taken to verify potency. Tablets and capsules are tested to ensure they are consistent in size and comply with USP standards for weight variation. Threshold utilizes USP disintegration standards* as its guidelines to ensure tablets will break up appropriately after ingestion, making the ingredients available for use by your body. *Under USP 25 standard conditions: Coated tablets: 50 minutes in water. Capsules: 45 minutes in buffered acetate or water. Rigorous Laboratory Procedures Methods used include: HPLC (High Performance Liquid Chromatography), IR (Fourier Transform Infrared), UV/Vis Spectrophotometry, Graphite Furnace Atomic Absorbance Spectroscopy, TLC (Thin Layer Chromatography), Microbiology testing, and organoleptic inspection including visual, color, odor, clarity, pH, and taste. Raw materials must comply with vendor Certificates of Analysis as well as with our rigorous specifications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=737) SIDE EFFECTS OF SYNTHETIC PROGESTIN DRUGS
Date:
July 25, 2005 09:56 PM
SIDE EFFECTS OF SYNTHETIC PROGESTIN DRUGS Premarin and Provera are two of the most commonly prescribed progestin drugs and come with a wide variety of side effects and health risks. Over 30 negative side effects are listed for Provera alone. Taking Provera during early pregnancy may actually cause a miscarriage or deformity of the developing fetus. Premarin is comprised of two different types of estrogen called estrone and estradiol, which have been linked with the development of certain kinds of cancer. The risks involved with taking these synthetic progestins is due to their chemical structures. For the most part, the compound resembles natural progesterone, therefore it binds to the same receptor sites as to natural progesterone. The altered portions of the molecule, however, convey a totally different signal to the cells involved. It is this atomic manipulation which poses alarming health risks to the body. Health risks which are not associated with natural hormonal precursors. A few of the side effects associated with synthetic progestins include: As is often the case, eventually the perils of synthetically derived plant analogues made health practitioners question their usage and the notion of using progesterone in its natural state has re-emerged. Unfortunately, its classification as a non-patentable simple substance relegates it to the status of an herbal supplement, which most doctors will not endorse. Synthetic drugs are more potent, usually easier to take, have a longer physiologic action and are patentable. For all of these reasons, natural phytomedicines have been shelved as relatively worthless in comparison. Chemically altered progesterone is considered technically superior when in reality, natural forms of progesterone may often be preferable.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=660) HISTORY
Date:
June 25, 2005 10:57 AM
HISTORY Ginkgo has achieved unprecedented popularity within the last decade and has become a familiar household term. Because interest in treating diseases like Alzheimer’s has escalated over the last decade, the biochemical capabilities of ginkgo in regard to brain function have been investigated and are still being researched. Ginkgo is one of those herbs that has become intrinsically connected with notions of herbal elixirs capable of pre s e rving youth and promoting longevity. Ginkgo comes from the oldest species of tree in the world dating back some 200 million years. Some ginkgo trees have been known to live well over an average of 1000 or more years. The ginkgo tree is also known as the “maidenhair tree” and would have probably become extinct if the trees had not been cultivated in Far Eastern temple gardens and nurtured by Oriental monks. Ginkgo is a deciduous conifer with separate male and female types. It resembles the pau d’arco tree and like pau d’arco, possesses an unusual immunity to insects and diseases. Ginkgo’s remarkable hardiness enabled it to survive the atomic blast at Hiroshima. Because of its unprecedented longevity, ginkgo biloba has sometimes been referred to as a living fossil. Ginkgo has been used in China for over 5000 years. The Chinese refer to the fruit of the ginkgo tree as pa-kwo. This fruit is sold in markets throughout China and resembles dried almonds. Ginkgo fruit is pleasant tasting when fresh, but can become quite disagreeable if allowed to get overly ripe. Asians have relied on extracts of the fan-shaped ginkgo leaf since 3,000 B.C. to heal a wide variety of ailments. The Chinese have been acquainted with the curative powers of ginkgo for centuries and have typically used the herb for ailments related to aging, such as circulatory disorders, mental confusion and memory loss. In China, ginkgo seeds, called baigou, are considered lung and kidney tonics and are used in conjunction with acupuncture. Ginkgo seeds also help to tonify the urinary system, so they are used in cases of incontinence and excessive urination.1 Practitioners of Chinese medicine routinely use ginkgo leaves. Ginkgo was introduced into Eu rope in 1730 and was we l l received, not for its medicinal value, but for its ornamental appeal. It is used extensively in landscaping because of its lovely fern-like leaf. It was brought to America in 1784 to the garden of William Hamilton who lived in Pennsylvania. Decades passed before the healing properties of ginkgo we re investigated. Consequently, it has been part of the herbal repertoire only since the 1980s. During this time, it became technically feasible to isolate the essential components of ginkgo. Pharmacologically, there are two groups of substances which are significant compounds found in ginkgo: the flavonoids, which give ginkgo its antioxidant action, and the terpenes, which help to inhibit the formation of blood clots. The majority of scientific interest has focused on Ginkgo’s ability to improve the circulation of blood. O ver the past twenty years, scientific testing on the plant has dramatically escalated. Ha rva rd professor Elias J. Core y, Ph . D , synthesized ginkgo’s active ingredient, ginkgolide B, for the first time in the laboratory. Consequently, stepped-up research in this country and in Eu rope resulted. Ginkgo has been the subject of over 300 scientific studies and continues to intrigue scientists. Much modern research has confirmed ancient applications of ginkgo as well as discovered new ones. Ginkgolide, the active component of the herb, is what creates most of ginkgo’s biochemical attributes. Exactly how ginkgolide B functions is not yet known. One theory is that the compound somehow interferes with a chemical found in the body called PAF (platelet activating factor). PAF has been implicated in cases of graft rejection, asthma and other immune disorders. PAF antagonists have been identified from a variety of medicinal plants. These compounds help to explain the pharmacological basis of several traditional medicines and provide a valuable new class of therapeutic agents. Particular attention has been paid to ginkgo’s powerful actions on the cardiovascular system. Thousands of Europeans use this herb for peripheral circulatory disorders. As a circulation booster, ginkgo has accumulated some impressive credentials. Because proper circulation is vital to each and every body function, virtually all body systems can benefit from ginkgo therapy. Ginkgo’s relationship to brain function has also spawned considerable interest. In 1985, Rudolf Weiss said of ginkgo, “ Significant improvement in mental states, emotional lability, memory, and the tendency to tire easily, have been reported.” Ginkgo is currently planted in groves and used for a number of medicinal purposes. It is harvested in the summer and can be used in extract, tincture or infusion forms. The therapeutic properties of ginkgo seem endless. Continuing re s e a rch promises to further uncover additional health benefits of this remarkable botanical. Ginkgo extracts are among the leading prescription medications in France and Germany. Currently, millions of prescriptions for ginkgo are written by physicians worldwide.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=447) The important role the liver plays in maintaining health
Date:
June 21, 2005 04:56 PM
Most practitioners who practice various forms of natural medicine know the important role the liver plays in maintaining health in general. The liver is involved in thousands of biochemical mechanisms making it second only to the brain in importance and complexity. Natural health practitioners are also acutely aware of the detrimental effects on the liver of modern living, with its chemicals, excessive fat intake, pesticides, hormones, and stress. This suggests that we as a culture are in need of liver support. History suggests, and modern research is supporting, that botanicals have an important role to play in supporting a healthy liver. Mechanistic Overview The liver has an almost miraculous ability to biochemically transform, break down, store, eliminate, and build up the plethora of chemicals to which it is exposed. Many botanicals have a very specific effect of modifying these biochemical processes. Some botanicals can enhance the liver?s phase I (cytochrome P450) and phase II (glutathione conjugation) detoxification processes, promote the flow and production of bile (one means of eliminating toxins), inhibit the attachment of viruses or chemical antagonists to hepatocytes, strongly enhance the liver?s powerful antioxidant systems, or promote the regeneration of liver tissue-the liver being the only organ in the body except the skin able to regenerate itself. Many botanicals have been used historically for promoting liver health. Today, modern research is confirming these benefits while shedding light on their mechanisms of action. Following is an overview of a number of these botanicals. Milk Thistle Silybum marianum The extract of the seeds of milk thistle is perhaps the most well researched of all the liver supportive botanicals. Part of its benefit has been in its ability to scavenge free radicals and to stimulate the regeneration of hepatocytes. In Germany, it is the botanical extract of choice for use in supporting a healthy liver. Typically, an extract yielding a minimum of 70% silymarin (a specific class of flavonoids) is used clinically at a dose of approximately 420 mg of the extract daily (Morazzoni and Bombardelli 1995). Schizandra Schisandra chinensis Schizandra, known as bei wu wei zi in China, is one of the most widely used tonics of Chinese herbalism. Its original use was to support the health of the heart, kidneys and lungs and as a longevity tonic. Modern research has focused attention on its role as an adaptogen and for supporting a healthy liver. Adaptogens are substances that positively affect overall health by reducing stress mechanisms which can contribute to a number of biochemical reactions that can be detrimental to health. While the mechanism of action of adaptogens has not been definitively determined, the existing literature suggests they work endocrinologically through the pituitary and adrenals and substantially reduce the negative effects that stress has on the system (Wagner et al. 1994). In China and Japan, the modern use of schizandra has focused on its benefit in those in need of liver support. In one review of its pharmacological activity, stabilization of liver enzymes was reported in more than 5,000 people. The benefits were experienced within 20 days of administration of schizandra with 75% of patients returning to normal values (Chang and But 1986). A limited number of controlled studies similarly reported on the beneficial effects of the equivalent of 1.5 grams of schizandra for reducing elevated liver enzymes (Liu 1991). There are three primary mechanisms of action of schizandra reported with regards to its ability to support a healthy liver: 1) its ability to reduce lipid peroxidation induced by a number of different antagonists (antioxidant activity); 2) induction of hepatomicrosomal cytochrome P-450; 3) stimulation of protein biosynthesis and liver glycogen (Liu 1991). Such mechanisms make schizandra ideal as a liver-supportive botanical that is underutilized in the West. Bupleurum Bupleurum chinense, B. falcatum Bupleurum, also known as chai hu in China, is perhaps the most important of liver-supportive botanicals in China and Japan, and, like schizandra, is far underutilized in the United States, except by traditional Chinese herbalists. Traditionally, it has been regarded as an herb that helps to normalize the function of the liver from a traditional Chinese perspective. Modern research has identified a group of compounds known as saikosaponins that strongly support liver health (in humans and rats). Mechanisms of action specifically regarding liver health identified for bupleurum include anti-inflammatory activity, as well as its ability to stimulate the production and release of bile, thus facilitating the detoxification process (Wagner et al. 1996). Sho-Saiko-To Minor Bupleurum In Chinese herbalism, herbs are seldom prescribed singularly. Rather they are combined according to very sophisticated principles of formulation based on the differential diagnosis of the patient. One of the most widely used and researched botanical formulas for the health of the liver used in China and Japan is Sho-Saiko-To, known in China as Xiao Chai Hu Tang (Minor Bupleurum). This classic formula consists of the following botanicals: ginger, scutellaria, jujube, ginseng, licorice, pinellia and bupleurum. It is widely used throughout Asia for supporting liver health and currently is the subject of phase II clinical trials at Sloan Kettering. The formula with its main ingredient, bupleurum, was first introduced in Japan by Chinese Buddhist priests between the 6th and 8th centuries. Modern research suggests that Sho-Saiko-To modulates the immune response, specifically in addition to other mechanisms, by increasing levels of interleukin and interferon (Huang et al. 2001). Holistic Context To the same extent that herbs are seldom used singularly in Chinese herbalism, they are similarly used within a broader context that incorporates dietary and other lifestyle changes to support the botanicals. In my clinic, I routinely recommend that patients eliminate alcohol, coffee, sugar, and refined foods from their diet and eat whole grain foods, fish, and several servings of green vegetables daily along with their herbal program. For these individuals this is a simple program to follow, and many are able to live a normal productive life with a greater level of liver health. Such a liver-supportive program must be maintained as a way of life to lessen the burden that modern society and exogenous factors put on our livers. Conclusion The herbal world offers a potential natural health care approach that focuses on protecting and restoring the health and functioning of the liver. Both traditional experience and modern investigation suggest that botanicals can play a role in world health, specifically in promoting liver health. Caution The use of botanicals should be used under the guidance of a qualified health care professional. The combined use of conventional and natural therapies may not be appropriate. Before attempting to combine such therapies, discuss your therapeutic options with your primary health care provider. References Chang HM, But PH. 1986. Pharmacology and applications of Chinese materia medica. World Science. Singapore. Huang et al. Semi-quantitative analysis of cytokine mRNA expression induced by the herbal medicine sho-saiko-to (TJ-9) using a gel doc system. J Clin Lab Anal 15: 199-209. Liu GT. 1991. Pharmacological actions and clinical uses of Fructus schizandrae in recent advances in Chinese herbal drugs-actions and uses. Scientific Press Beijing. Morazzoni P, Bombardelli E. 1995. Silybum marianum (Carduus marianus). Fitoterapia LXVI (1):3-42. Wagner H, Noerr N. Winterhoff K. 1994. Plant adaptogens. Phytomedicine 1: 63-76. Wagner H, Bauer R, Peigen X, Jianming C, Offermann F. 1996. Chinese Drug monographs and analysis: Radix Bupleuri (chaihu). Verlag fuer Ganzheitliche Medizin Koetzting/Bayer. Wald, Germany.
Michael Tierra, L. Ac., O.M.D., is a clinician and world-renowned author of the best-selling Way of Herbs and Planetary Herbology. As product formulator for Planetary Formulas, he draws on 30 years of clinical experience to create formulas renowned for their dependability and effectiveness.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=381) Real Solutions 
Date:
June 10, 2005 04:01 PM
Real Solutions by Susan Risoli Energy Times, November 1, 1997 The alarm sounds, you stumble out of bed and head to the bathroom. Suddenly, a burning sting wakes you with a jolt as you begin to urinate. One doctor visit later, you're on a strict antibiotic regimen to treat your urinary problem. Urinary tract infections (UTIs) affect 8 million to 10 million Americans, mostly women, each year. The culprit: the bacteria E. coli. Neglect may allow a UTI to spread to the bladder (where it causes cystitis), or kidneys: possibly life-threatening. The good news: medical experts recognize that a diet change and avoiding certain risk factors may help fight off UTIs. According to the Mayo Foundation for Medical Education and Research, about 20% of women experience UTI at least once, and many suffer recurrences. Sexually active women tend to incur more UTIs because of anatomical vagaries: the bladder sits just above the vagina, while the urethra, a structure from the bladder to the outside, protrudes in a tubelike ridge down the top part of the vagina to just above the vaginal opening. This structure allows sexual intercourse to push infecting bacteria into the urethra. Women's vulnerability to UTI also derives from their short urethras which are located near the rectum, a main source of UTI germs. These tubes provide an easy path to a bacterial home in the bladder. Another risk booster: pelvic exams which may increase chances of UTI. A 1996 study conducted at the University of Illinois at Chicago and reported in the Archives of Family Medicine (1996;5:357-360) found that 43% of women with UTIs had received a pelvic examination within the two months preceding infection. Only 16% of the uninfected had been examined. Bladder infections can occur frequently in postmenopausal women due to thinning and drying of the vaginal lining. And mid-life women are not immune. "With the loss of estrogen support, the urethra becomes less flexible and elastic and, like the vagina, it can become easily irritated after sexual intercourse and, thus, much more prone to infection," reports Susan Lark, MD, in her book, Women's Health Companion: Self Help Nutrition Guide and Cookbook (Celestial Arts). "As women age, the lower urinary tract also stops manufacturing anti-adherence factors, which help to prevent bacteria from attaching to the bladder wall." Every woman should keep her own "female" botanicals on hand to help boost her immune system when she is at high risk of developing a bladder infection. These include: Cranberry: This immune-boosting, vitamin C-rich berry prevents germs from invading the lining of the urinary tract. A 1994 study of 153 elderly women conducted by researchers at the Harvard Medical School and published in the Journal of the American Medical Association (1994:271: 751-4) showed that cranberry juice may keep harmful bacteria at reduced levels. More recently, a study by Amy B. Howell, PhD, and a team at Rutgers University found that cranberries contain a type of condensed tannin, a chemical compound called proanthocyanidins, that seemed to stunt the growth of E. coli, preventing it from adhering to the walls of the bladder and kidneys. "However, once you have an infection, cranberry juice cannot eradicate the bacteria. So drinking cranberry juice may be helpful in preventing an infection, but not in treating an existing one," according to Larrian Gillespie, MD, in her book You Don't have to Live with Cystitis (Avon Books). Drinking two glasses of juice a day can help if you're UTI-prone. To avoid the sugar added to cranberry juice, concentrated cranberries are available in a gel-cap form. Echinacea: This North American herb bolsters immune function and is believed to possess antiseptic and antiviral properties which may rev up the white blood cells that fight infection, reports John Cammarta, MD, in his book A Physician's Guide To Herbal Wellness (Chicago Review Press). While cranberry is most commonly recommended for prevention, other herbs can also kill bacteria and are diuretic. These include: Barberry: "The chemical berberine found in this herb is an impressive infection fighter. Studies show it kills the bacteria responsible for urinary tract infections," says author Jim O'Brien in his book Herbal Cures for Common Ailments (Globe). O'Brien recommends making a tea with one half teaspoon of powdered root bark, then put it on low boil for 30 minutes. "The taste is unpleasant, so you may wish to add natural sweeteners and flavorings." Uva-ursi: contains the ingredient arbutin, which fights germs in the urinary tract. "In addition," adds O'Brien, "the herb contains several diuretics that help flush the urinary tract, leading to faster healing. It also has several tannins, which act as powerful astringents drying out swollen, infected tissue. A third property of uva-ursi is allantoin, which promotes the growth of new cells." "For this herb to be effective you must not eat or drink anything of acidic nature, such as citrus fruits or juices. Don't even take vitamin C supplements while using it," cautions O'Brien. Coping With Pain In her book Herbal Remedies for Women (Prima), medical herbalist Amanda McQuade Crawford offers an herbal recipe to help restore the urinary tract's normal pH. Herbal Formula I calls for 4 ounces of uva-ursi leaf, three ounces of marshmallow leaf, two ounces of yarrow flower (omit during pregnancy) and one ounce (or to taste) cinnamon bark. Steep the herbs for 10 to 20 minutes, then strain through bamboo or wire mesh. Drink 2 to 5 cups daily for 10 days. Crawford advocates drinking one to two cups per day for a week to 10 days after all symptoms have disappeared. Diet Strategies Urologist Gillespie has found that women with cystitis may notice certain foods and beverages (such as alcohol and acidic foods) exacerbate problems of pain and burning. Gillespie recommends cystitis sufferers avoid foods like apple juice, apples, apricots, melon, carbonated drinks, spicy foods, citrus fruits, coffee, ginger, grapes, guava, lemon juice, peaches, pineapple, plums, rhubarb, strawberries, tea, tomatoes and vinegar. Limit refined sugar: this nutrient may stunt immune reactions. Most importantly, you can lower the risk of UTIs by drinking liquids. Water helps flush bacteria from the body so drink at least 6 to 8 eight-ounce glasses of filtered water daily.
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Artemisinin health benefits
