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Search Term: " Flawed "
Fish Oil Supplements: Are They Good for Cardiovascular Health?   
Date:
March 23, 2017 08:44 AM
Conventional wisdom has long been that fish oil supplements are very beneficial for heart health. In fact, the American Heart Association (AHA) recommends fish oil for heart patients. However, there is some disagreement about the effectiveness and safety of fish oil. Read this article and discover 3 reasons why some data may be flawed regarding this supplement along with concerns regarding safety of some fish oil. In the end, eating fish may be more heart-healthy. Key Takeaways:
"Fish oil contains omega-3 fatty acids, which, when consumed by eating fatty fish, can cause blood vessel relaxation, reduced blood clotting, reduced inflammation and possibly stabilization of heart rhythm." Read more: https://health.clevelandclinic.org/2017/03/fish-oil-supplements-good-cardiovascular-health/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4266) Benefits of herb chaste berry for women 
Date:
January 17, 2014 08:20 AM
Premenstrual syndrome impacts over 70% to 90% of ladies before menopause in the US and less for ladies in Southeast Asia in light of their contrast in living style and social structure. The event of premenstrual syndrome (PMS) have more than multiplied in the course of recent years because of the acknowledgement of it as a therapeutic condition that is initiated by bad eating methodology with high in soaked sustenance. Premenstrual syndrome is characterized as Flawed capacity of the ovaries identified with the ladies' menstrual cycle, it impacts a ladies' physical and enthusiastic state, and frequently meddles with every day exercises as an aftereffect of hormone change. The syndrome happens one to two prior week’s monthly cycle and after that decays when the period begins. In this article, we will talk about how standing berry tree impacts ladies with PMS. Chaste Berry I. Definition Chaste berry tree is an exceptionally significant herb; it has been utilized as drug since old Greek for menstrual issue incorporating absence of ovulation. Today the herb is well known for treating side effects of hormone lopsidedness. II. How chaste berry tree impacts ladies with premenstrual syndrome it hard to accept that chaste beery tree holds no plant estrogen yet has been adequately utilized within treating premenstrual syndrome due to the accompanying lands 1. Iridoid Chaste beery tree holds iridoid incorporating aucubin and agnuside which are frequently intermediates in the bio combination of alkaloid. It serves to enhance invulnerable framework battling against irritation and serves to avoid muscle spam bringing about decreasing menstrual ache and spasms. 2. Androstenedione is the normal antecedent of male and female sex hormone generated by adrenal organ, chaste berry tree holds androstenedione which not just serves to tie the levels of terrible estrogen additionally equalize the levels of testosterone in the ladies figure bringing about decreasing the male example for some ladies with PMS. 3. Key oil Chaste berry tree holds cineol, pinene, castine and different substances, it serves to unwind the apprehensive framework and muscle that serves to diminish side effects of anxious pressure, for example, tension discouragement, menstrual agony and spasms brought about by over animated uterus muscle. It likewise serves to expand liver capacity for overall health. 4. Alkaloid As and alkaloid, it serves to diminish the manifestations of breast delicacy and bosom ache brought about over preparation of prolaction prior and then afterward ovulation. 5. Progesterone The chaste berry tree serves to repress if the levels of progesterone in the event that it is excessively high or raise the levels of progesterone in the event that it is excessively low, in this way, diminishing the danger of hormone awkwardness between estrogen and progesterone.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2969) Garcinia Cambogia
Date:
August 28, 2008 09:33 AM
Garcinia Cambogia is found naturally in India and parts of Asia, and also on the Pacific coast of South and Central America all the way from Peru up to Mexico, and likes a humid forested environment. Also known as Brindall berries, garcinia is believed to act as an appetite suppressant and allows you to lose weight by diminishing your desire for food. The Malabar tamarind, as it is also known, is about the size of an orange resembling a small pumpkin, and an extract from the fruit and rind is used in several weight loss products. The health risks presented by synthetic diet pills render a natural product extremely attractive were it to be effective. So can Garcia curb your appetite? What is the scientific evidence for it, and what biochemical route would it take? Although tests on animals have been very positive, human results have been inconsistent. In some double blind tests using a placebo, weight loss was up to three times that of the control, but in others there was no apparent difference between those taking garcinia, and those given a placebo. However, doubts have been raised of the validity of some of the negative tests, so what does science tell us? The active ingredient in the cambogia extract is hydroxycitric acid (HCA), which is a powerful inhibitor of ATP citrate lyase, an enzyme that catalyzes the reaction between citrate and Coenzyme A to Acetyl CoA and oxaloacetate. Since the acetyl CoA is necessary in the synthesis of fatty acids and lipogenesis (the conversion of glucose to fatty acids), then anything that inhibits the biosynthesis of acetyl CoA must help to reduce the amount of fat stored in your body. By inhibiting this reaction, that occurs outside the mitochondria so is not a direct part of the Citric Acid Cycle, HCA should theoretically suppress the formation of fats from carbohydrates, reduce food intake and thereby induce weight loss. But that is not the only mechanism. A study at Georgetown University in Washington found that after 8 weeks of taking the garcinia extract, there was a 5.4% reduction in body weight and body mass index, and a significant reduction in low density lipoproteins (LDL) and triglycerides with an associated rise in high density lipoproteins (HDL). This is good news for those suffering from high cholesterol levels, since the LDL lipoproteins are those that carry cholesterol to the major blood vessels, and which when oxidized by free radicals deposit fatty plaques on the artery walls. These plaques constrict the arteries and the resultant atherosclerosis can lead to cardiac problems and strokes. HDL lipoproteins carry cholesterol back to the liver for destruction, and is known popularly as ‘good cholesterol’. The studies also indicated modifications to certain indicators of the status of fat deposits in the body and of appetite modifiers in the brain. In this respect they found 38% decreases in serum leptin and increases in serotonin levels of 44%, and the excretion of fat metabolites in the urine increased from between 32% and 104%. These are significant findings, and further research has indicated that HCA helps to suppress appetite. Serum leptin is an indicator of the level of fat stores in the body, and as the leptin levels in the blood reduces, the hypothalamus is given an instruction to increase the appetite so as to increase the fat levels again. However, it is believed that HCA possesses leptin-like properties, and this signal is either not generated or is modulated. The increase in serotonin has the same effect. It is known that serotonin controls the appetite, although the exact mechanism has not yet been established. What is known is that serotonin activates certain neurons and melanocortin-4 receptors (MC4R) in the brain, that not only curb appetite but also block the effect of other neurons that would normally increase appetite by blocking the effect of MC4Rs. This is how the banned anti-obesity and serotonin inciting drug Fen-Phen operated, and it appears that the hydroxycitric acid in garcinia cambogia extract acts in a similar, but safer, way. The problem with drugs such as Feb-Phen was that they created cardiac problems which could be dangerous to obese people whose hearts might have been weakened. However, now that the biological pathway by which serotonin controls weight is believed to be known, if not fully understood, the way is becoming clearer as to how safer weight loss pills, acting through appetite suppression, might be developed. It also provides a valid scientific explanation for the effect of garcinia cambogia extract which might in itself prove to be that safer way. The biochemistry supports the evidence of its effect on those wanting to lose weight, and also bolsters the claims that those tests and trials found to be negative were in some way Flawed. Until the full chemical pathway is understood, the factors that can lead to Flawed tests are unknown, although one could be the use of excessive fiber in some trials that could reduce the effect of the extract. One of the effects of HCA is to limit the ability of your body to convert carbohydrates into fat (the Acetyl CoA inhibition mentioned above). That, combined with suppression of your appetite and a higher rate of thermogenesis, prevents the body from storing excess carbohydrates as fat. Instead you will have increased energy levels, so you should exercise to use this up while taking garcinia extract. For this reason it is popular with athletes and bodybuilders seeking an energy source that has not yet been banned from sport. Although diet pills based on the same principle had side-effects and could make the user feel on edge, there are none known with garcinia. However, it is possible to reduce the absorption of some essential nutrients due to appetite suppression, so do not exceed the recommended dose. An excessive amount can also led to gastric discomfort, but none of these effects have been noted when the recommended doses have been adhered to.
However, if you are diabetic, pregnant or a nursing mother, you should consult with your physician or health professional before taking the extract. Garcinia Cambogia presents no specific risk to such people, and this warning should be given for all non-prescriptive treatments that your physician might be unaware of you taking.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1876) Can the Fatty Acid CLA Help me Lose Weight ?
Date:
July 14, 2008 03:28 PM
CLA is conjugated linoleic acid, a compound known as a trans fatty acid due to its stereochemistry, and while trans fatty acids are generally regarded as harmful, CLA is not because it is conjugated. This means that it has alternate single and double bonds in the backbone carbon chain, and the overall energy of the molecule is therefore reduced. Linoleic acid itself is one of the omega-6 fatty acids, the 6 referring to the double bond at the sixth carbon from the omega and of the carbon backbone chain. It is believed to be the cause of heart disease and obesity due to its increasing use in the diet at the expense of omega-3 fatty acids. When the molecule is conjugated, however, the fatty acid has different chemical properties to the standard isomer, and natural CLA is mainly found in cattle products, such as beef and dairy products. Conjugated linoleic acid is present in cattle because it is formed when linoleic acid is converted to oleic acid by rumen bacteria, that are responsible for the microbial fermentation of the feed of ruminant animals such as sheep and cattle. When oleic acid is formed, so too is CLA. However, the form used in supplements is manufactured from vegetable oils, and therefore suitable for use by vegetarians. The usual vegetable oils used are safflower oil and sunflower oil. It is believed to possess several beneficial properties, including antioxidant and anti-cancer properties, but it is for its ability to reduce body fat that it is best known to most people. A growing amount of information is being collected on the use of CLA as a supplement in the weight loss industry, although there are as yet no definitive mechanisms that explain its action. However, recent studies have indicated it possess properties that can help to reduce the levels of low density lipoproteins in the blood, and reduce the possibility of atherosclerosis due to LDL oxidation by free radicals. It is also theorized that CLA in some way regulates the prostaglandin biosynthesis that controls the level of hormones in the body that can regulate growth. An increase in growth hormones is one way in which athletes promote an increase in muscle bulk, while reducing their fatty tissue mass. CLA is also purported to increase thermogenesis, and so promote the loss of body fat and overall weight. Although most studies on the effect of conjugated linoleic acid in reducing body weight have been carried out on animals, recent animal studies have indicated that might not so much reduce weight, as to increase muscle bulk while reducing that of body fat. The end result, therefore, is not a loss of weight, but a leaner body that has more muscle and less fat. All it needs is the results on animals to be transferred to humans, and this, of course, is frequently the case. However, initial studies on the use of CLA in the human diet have been very positive, so the signs are good. Most scientific progress in human biochemistry has been obtained by virtue of prior studies on animals. These studies, of course, have been beneficial to the animals, making them leaner and much fitter than they otherwise would have been. It is believed that the same will be true of humans taking CLA as a supplement. In fact, recent studies are split about 50/50 with regard to the effects on humans. While some studies have shown no benefit, about an equal number have shown a positive benefit in the reduction in the mass of fat in the body. Some of the negative studies may have been Flawed in measuring total body weight, and not the relative amounts of muscle and fat, and also basing their results on people already with a low level of fat in their body. In that respect, then, the results look very favorable, and taking CLA as a supplement is likely to help you to reduce fat and increase muscle, if not altogether lose total body weight. However, is that not the end result that most people want? They might not want to be lighter in weight, just to have more muscle mass and less fat tissue. In a study shown at a 2002 Experimental Biology meeting, it was shown that is was possible to substantially reduce body fat mass by taking CLA alone, and when it was taken in association with guarana, both the size and the number of fats cells in the body were reduced by 50%. However it has also been shown that CLA can be oxidized by free radicals shortly after ingestion, and that sesame lignans help to prevent this. Since sesame lignans can also be used in conjunction with CLA to reduce fat by increasing the level of fatty acid oxidation in the liver, than the benefit of CLA seems obvious. The antioxidant effect of CLA is one possible explanation for its anti-cancer properties, though there are others. Its antioxidant properties also have an anti-catabolic effect, in that it can help to prevent the wastage of muscle tissue. The FDA has published studies that attest to these anti-cancer properties. Diabetics, however, should consult with their physician before taking CLA as a supplement, since there is a body of thought that it reduces sensitivity to insulin. Others believe the opposite, so more studies might be needed in this aspect of the substance before it can be said to be safe for use by diabetics. Over recent years, the American diet has increased significantly in its content of the undesirable linoleic acid, due to its ubiquitous presence in margarines, and has reduced in CLA due to modern farming methods. Cattle feeding techniques have resulting in a reduction of CLA in meat products and milk, although eggs are still a rich source, and the CLA in eggs can resist temperatures used in normal cooking methods such as frying, boiling, etc. It is this CLA deficiency in the diet that has been proposed as one of the reasons for the current obesity problem in the USA. The European diet contains more beneficial fatty acids in general than the American diet.
However, there is an increasing body of evidence being accumulated that collectively that suggests almost unequivocally that CLA can help you lose body fat. Unless you are diabetic, there are few if any contra-indications and an increasing number of people are finding it effective not only to lose body fat, but to replace it with hard lean muscle.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1837) NHA/Washington Update - Statistics Lie 
Date:
April 06, 2007 04:57 PM
The mass media targets antioxidants with misleading stats. The smear campaign against nutritional supplements continues in 2007, with headlines such as the following: “Antioxidants Don’t help You Live Longer,” “Antioxidants Might be Dangerous,” “Antioxidants Do Not Prevent Disease and May Increase Mortality.” Do you notice a theme? Antioxidants are the latest target for media manipulators seeking to steer the public away from life-enhancing nutrition. The study that spawned these alarmist headlines, first published in the Journal of the American Medical Association, is a “meta-analysis”; this means it draws its conclusions from a number of different studies. In this case, 68 studies involving 232,606 people were analyzed. Meta-analyses are an example of how easily statistics can lie. Deception Exposed Like 2004’s infamous vitamin E-bashing meta-analysis (which proclaimed vitamin E to be deadly, even though it focused on elderly patients who were already stricken with disease), the recent meta-analysis of antioxidants has a preordained outcome—results are determined by which studies are chosen for analysis. Experts have pointed out significant flaws in the execution of this meta-analysis; for example, it includes studies that administered many different combinations of antioxidants, and in varying doses. In addition, these Hitler-skelter antioxidants and dosages are scattered across a wide range of people, everyone from male doctors to elderly nursing home patients. Finally, this meta-analysis neglected to include the most significant antioxidant study ever conducted in its findings. The china study, which in surveying 800 million people was one of the most comprehensive studies of its kind, verified antioxidants effectiveness in fighting cancer, heart disease and stroke. Why was it not included in the meta-analysis? Even a junior high school science student would question this meta-analysis’s statistical significance. So how can mass media transform this Flawed study into headlines that proclaim antioxidants will kill you? The answer is because the media gets away with it. In our fast paced world, where celebrity rehab stints are front page news, fact-driven journalism is fading—and distracted news readers are enabling its demise. The solution? Consider media reports with awareness and intelligence, and never assume that headlines speak truthfully. The recent antioxidant bashing study crumbles when subjected to awareness and intelligence. In addition to the obvious study flaws, and even more telling: stories coving the study with headlines proclaiming “antioxidants may increase mortality” are grievously misleading; as it turns out, the study did not identify any causes of death—which were surely diverse given that the study tracked over 200,000 diverse people. Believe the headlines, however, an antioxidants causing all the deaths when in fact they probably caused none—an example of the absurd “association with out causation” logic that may destroy our right to take safe, natural supplements. Continue investigating and you will find that Denham Harman, MD, PhD, the “father of the free radical theory of aging,” antioxidants pioneer and professor emeritus at the University of Nebraska Medical Center, is able-bodied and active at age 91. Harman takes antioxidants vitamin C, vitamin E and selenium daily—a revelation with more credibility than any antioxidant bashing hatchet-job study. Educate yourself about antioxidants and other supplements that Congress is trying to take away from you. Fight to keep your health under your own control, always. Patronize the natural health food store that are committed to providing you with quality products and reliable knowledge. For more information, visit www.nha2007.com
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Premestrual Syndrome (PMS)
