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Search Term: " Hypericum "
st johns wort and depression   
Date:
October 10, 2012 12:10 PM
St. John's Wort St. John's Wort, also scientifically known as Hypericum perforatum, or Klamath Weed, is a herb with yellow flowers. It has numerous composition of strong compounds like hypericin and hyperforin thathave shown evidence of antibacterial, antidepressant, anti-inflammatory, anti-viral and antioxidant properties. St John Wort can be used to treat mild session of anxiety depression and mood swings, the hyperforin chemical found in it, elevates the level of the neurotransmitters (dopamine, serotonin) that relay information in between cell and play a vital role in the nervous system. The herb has the ability to inhibit chemical associated with anxiety and depression and thus induce a sense of wellbeing and help moderate depression, anxiety, mood swings, chronic fatigue and low energy level. Other benefit of the St John Wort is that it can help treat hangover and alcoholism; it also helps prevent the risk of getting Parkinson disease. It antibiotic and anti-viral properties can help treat congested sinus or a chronic cough its antibacterial and analgesic propertied help to treat wounds and burn.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2684) What Makes St Johns Wort Good For Depression And Anxiety? 
Date:
September 18, 2012 09:18 PM
St Johns wort St Johns wort is a particular plant species. Firstly, in ancient Greek the medicinal uses of St Johns wort are recognized. It is an herb with yellow flowers. It contains active ingredients like flavonoids, anthrancenes, volatile oil and sugar alcohol which are used for medicinal purpose. St Johns wort binomial name Hypericum perforatum is also considered as wild plant, herb and weed. The other common names for this plant are Amber Touch-and-heel, goat weed, Klamath weed, Rosin rose and Tipton weed. As it is an herb its leaves and flowers are used for medicinal purpose. What is St Johns wort? St Johns wort is considered as a medicinal plant. It has yellow flowers which are used for medical purposes in various parts of the world. It is an herbal remedy to treat depression. This medicinal plant is also used for migraine, headache, muscle pain, chronic fatigue syndrome. It is also used for cancer and HIV/AIDS. St Johns is known as natural herbal remedy for mild to moderate depression. This highly valuable contains a chemical known as hypericin which effects against depression. This chemical act as mediatator in the nervous system which control the mood. Does St Johns worth help depression? Depression has now become a common problem in humans now days. Due to the side effects of antidepressant medications, people are frequently moving towards natural remedies. St John wort is a complete health booster for the entire nervous system. It is recommended as a useful herbal remedy. It is scientifically proven that this particular plant is effective for mild to moderate depression. It has been used to treat mental disorders. St John wort is commonly used for depression and the conditions which are responsible depression such as anxiety, tiredness and sleep disorders. In most of the countries it is widely prescribed for depression. Wort is beneficial to people with mild depression but it is less effective on major depression. St Johns wort medicinal properties:This medicinal plant is a powerful medicine.It is effective and well tolerated by the patients.You can feel yourself improving within the first week of usage of St John wort.As it is well tolerated by the patients, you can see fast results with fewer side effects.It decreases anxiety related to depression.It includes medicinal properties like antibacterial, anti inflammatory, antiviral, antidepressant and pain relieving.Traditionally it has been used to cure burns, headache, wounds, etc. Though this is a powerful and remarkable medicine for treating mild to moderate depression, but still there is a question in the mind of health experts regarding major depression? In accordance with this, medicinal wort is less effective for the people who are taking other medications. St John wort is not effective on severe depression as discussed earlier. St John wort causes drug interaction so it might not be the right choice for the people who take other medication. You cannot ignore St Johns Wort, as it is a natural remedy for treatment of depression in spite of having few side effects.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2675) Herbs For Depression: Alternative Solutions To Improve Your Mood
Date:
February 17, 2012 07:29 AM
What Herbs Can Help With Depression?Depression - Introduction: Depression is brain system disorders that can make many people weaken from functioning normally during episodic events. Some types of depression actually paralyze people and prevent them from leading a normal life. In addition, it is important for individuals who suffer from depression to realize, that they do not have to hide this condition and think that they suffer alone. In fact, many people have some form of depressive disorder. Something must be done is to take action to reduce their depression treatment. Depression - Herbs That Can Help Reduce: Depression and anxiety are very common in the modern world, and there is no single drug offers an effective cure. However, there are many herbal remedies that can help you reduce depression: 1. St John's Wort (Hypericum perforatum). St Johns Wortis a eternalcompoundwith littleyellow flowers that originally came from Europe, but also widely used intoAmerican. It is used extensively by European physicians to reducedepression. Two compounds, hypericin and hyperforin, give St. John's Wort potencyto keepmood and fight depression. St. John's Wort also contains flavonoids and proanthoclanidin substances that can affect the peace and balance to the nervous system. 2. Valerian. Valerian is the most popular herbs to relieve nervous tension. Sedative effect was first recognized in the seventeenth century, and since then enjoyed a long history of safe use effectively. Research believe that valerian binds to GABA receptors, which produces lower levels of anxiety. This does not completely eliminate anxiety, just change the way that the brain and your body reacts physiologically and give peace to the nervous system. 3. Kava kava. Kava kava is a plant found in the Pacific Islands. The roots and bark are usually used as a slurry and then combined with cold water to drink. Due to the active compounds in Kava kava, a chemical known as kavalactone, destroyed by high temperatures, use cold or warm water is very important in its preparation. And studies have suggested a correlation between active ingredients and enhanced mood. To be specific, Kava Kava is estimated to have a relaxing impactand reduce fatigue in the human brain. 4. Ginkgo Biloba. Ginkgo Biloba is the oldest tree used by China to treat various diseases. In the 1700's it has been introduced in Europe. Ginkgo Biloba is mainly composed of active components such as terpene lactones and flavnonoids, which gives a positive effect on mental well-being. With capabilities that are known to increase blood circulation to the brain, this herb has also decreasethe amount of free radicals in the body and brain, so it appears relaxation that can reduce stress or depression. 5. Lavender Oils. Lavender is a very popular herbal aroma is mainly due to growing importance as a beautiful and essential oils. The smell of lavender oil can stimulate the nerves that send signals to the brain limbic system, which spur the peace and comfort to the physiological function of human emotional. Lavender has been believed by experts to help relieve anxiety, tension, stress and fear that are part of depression. 6. Lemon Balm. Lemon Balm serves to inhibit the production of thyroid hormones and can help treat primary or secondary brain diseases and to provide a stimulant for the antioxidant that gives relief to your brain space. Some modern studies have found that lemon balm is useful for promoting sleep quality and reduce the effects of depression tranquility. 7. Chamomile. Chamomile is a very popular herb in Europe and has been widely used for centuries agoas a treatment for some diseases, such as sleep disorders, stress, anxiety, and depression. Other active compositions including flavonoids and matricinid which gives a feeling of relaxation and regulate the nervous system. Now it has proven to be one of the safest herbs on the market to relieve stress. Conclusion: Although the use of herbs for depression is widely spread, overall there is definitely reaction for the benefits of herbs for reduce depression disorders. Apparent when compared with normally drugs for depression that usually can not serve as the first choice of treatment options. However, when other treatments have failed more established, might have to be used.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2582) Herbs For Depression
Date:
December 13, 2010 12:34 PM
Fight Depression with Natural Herbs Before discussing treating depression with natural herbs we should first consider depression itself: what is it and what causes people to become depressed? Psychiatrists and psychologists will suggest a number of definitions although most experts agree that there are two forms of depression. Causes of Depression Exogenous depression comes about as a result of external factors such as bereavement, heavy debt, job loss, etc, while endogenous depression comes from within and is believed to be due to biochemical problems, including food allergies, hormonal changes, thyroid problems, nutritional deficiencies, particularly Vitamin B deficiency, and addictions. There are many other reasons for people becoming depressed, some of which can be established by the particular symptoms of the individual. In many cases of depression the external factors are often easier to treat than those due to internal factors. Many exogenous causes of depression such as bereavement are alleviated through time, while causes such as job loss and debt can be resolved once the cause has been rectified: thus, if the patient is no longer in debt or is re-employed, the depression tends to disappear with the cause. Symptoms of Depression Depression is not diagnosed from a single symptom, but from a number of symptoms that can point to a person being clinically depressed and requiring treatment. Among the symptoms of depression are:
Prolonged periods of sadness or despair Forms of Depression Many normal people can suffer one or two of the above systems, and would not be diagnosed as depressed because of it. We can all get mood swings, feel a bit worthless now and again or be unable to concentrate or focus at times, but that does not mean we are clinically depressed. Depression would not be diagnosed in a patient with just one of these symptoms but five or more likely would be. In fact, the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders deem the patient suffering clinical depression if displaying 5 or more of the bottom 8 symptoms above for a month or more. This is believed to be the case with around 17 million Americans so it is a significant problem. Manic depression is otherwise known as bipolar disorder, where patients have large mood swings from high and extreme hyperactivity and excitability to very low deeply depressive moods and is a clinical condition generally treated using drugs. Treatment of Depression With Natural Herbs The usual treatments are drugs that often have undesirable side effects; so many people are trying natural remedies instead. There are a number of herbs that can be used to treat depression, one of the most familiar being St. John's Wort. However, there are others, and here is a synopsis of each. St. John's Wort
However, it can also be used in cases of severe depression, and a report in the Cochrane Database Review[8(4)] by K. Linde, M.M. Berner and L. Kriston in 2008 stated that of 29 separate tests carried out on a total of over 5,000 patients, the conclusion was that St. John's wort extracts were at least as good in treating severe depression with 5 times lower side-effects as tricyclic antidepressants and twice lower than the new selective serotonin reuptake inhibitors (SSRI).
It should be stated, however, that one trial on 340 subjects indicated no improvement over a placebo. However, the anti-depressive drug sertraline (Zoloft) was also shown to be no better than the placebo in this test, so some doubts must lie regarding its accuracy. Of all the herbal treatments, St. John's wort has had most testing carried out and it seems to be effective in treating mild to severe depression although not all experts are yet agreed. Kava Kava Root
However, it is doubtful if its effects are permanent and so it may be less of a depression cure as a short-medium term treatment. Its effects are also variable on different people, some describing it as making them feel relaxed and 'dreamy', while others find it therapeutic and making them feel better in themselves.
Kava kava should not be taken without your doctor knowing about because there have been concerns about its effect on the liver if taken in excess. A European-wide ban was lifted about two years ago after testing found the risks of taking it to be very low. It has been used for centuries as an intoxicating drink on islands such as Fiji. Passion Flower
Through the intervention of GABA, passion flower extract helps in reducing anxiety levels and makes you feel a lot calmer. If you suffer forms of depression that make you hyper or excitable, passion flower will help to reduce this and also helps to cure insomnia. It is a component of many natural sleeping pills. These are just three natural substances that can be used to treat depression. However, you must inform your doctor or physician if you decide to take them since they may interfere with or change the effect of any antidepressant drug you are currently taking.
Call today for natural remedies for depression
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2207) St. John's Wort
Date:
June 22, 2008 08:52 AM
St. John's Wort is a plant with yellow flowers that researchers continue to look at for its health and well-being benefits. A perennial herb, it is from Europe and found its way to America with settlers. It is commonplace in meadows and fields. The first recorded use of St. John's Wort was in ancient Greece. It also goes by the following names: Hypericum, Klamath weed and goat weed. For centuries, this plant has found use as a medicine for depression and anxiety. People often used it to treat mental conditions and nerve pain. Today, people use the herb to treat sleep disorders and anxiety as well as a treatment for mild to moderate depression. In Europe, St. John's Wort is available as a prescription medicine and finds wide use there. In the United States, it is an herbal supplement and does not have classification by the government as a prescription medicine. However, there is great interest in the U.S. in this herb's capabilities as treatment for depression. Studies show St. John's Wort has a minimal effect on major depression. There is evidence though that it is a useful herb for treating milder depression. Some studies show it acts similar to synthetic antidepressants by affecting the neurotransmitters in the brain. There is also evidence that it produces fewer side effects than these synthetics. In North America, St. John's Wort comes in capsule, tablet, liquid extract, oil-based skin lotions and tea form. The flower tops of the plant find use in tea formulations. The major active elements in the herb, considered by some researchers as antidepressants, are hyperforin and hypericin. Studies suggest that the hyperforin in the herb plays a part in helping people decrease alcohol consumption. In addition, hyperforin has beneficial antibacterial properties. The plant also contains essential oils and flavonoids. Native Americans have a history of use of St. John's Wort as an anti-inflammatory, antiseptic and astringent agent. If you decide to try St. John's Wort, you must consult with a health care professional first, as this herb interacts with other medications. Evidence shows that it can affect anticoagulant drugs and contraceptive pills. It can also affect medication needed to treat high blood pressure. One study of St. John's Wort showed it was beneficial to a group who consumed 300 mg. three times daily compared to a group who took a placebo only. This study occurred over a four-week period. Sixty-seven percent of the St. John's Wort group experienced improvement of their depression compared to 28 percent of the placebo group. This study included only those suffering from mild depression. What was important in this study was that there were no adverse side effects from the St. John's Wort as compared to synthetic antidepressants. This was significant because many patients often refuse standard antidepressants because of the harmful and bothersome side effects they produce. There is no denying that St. John's Wort has a long tradition as a medicine to treat anxiety and depression. This is why studies continue into its effectiveness. Researchers do not want to ignore repeated testimonials about the herb's antidepressant capabilities; they seek to make sure these claims are legitimate by having facts to back them up. Thirty-seven trials that met criteria for being credible received recognition concerning St. John's Wort. They received summarization in a study. (Cochrane Database of Systematic Reviews 1998, Issue 4. Art. No.: CD000448. DOI: 10.1002/14651858.CD000448.pub2.) The conclusion reached upon analysis of the studies showed St. John's Wort could benefit those with milder types of depression. No conclusive evidence exists that more severe types receive anything more than minimum benefits from the St. John's Wort products that were part of the studies. The researchers stress that their analysis applies only to certain products they tested, not every St. Johns Wort formulation on the market. Many are of different pharmaceutical quality and of different strengths and purities.
Research will continue into this natural product that the earth provides us. At the very least, St. John's Wort does help some forms of depression. The jury is out on whether its benefits will extend to those who suffer harsher forms of the debilitating mental condition that affects millions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1824) Natural Remedies For Bumps, Bruises, Scrapes, and Insect Bites
Date:
November 10, 2007 09:52 AM
Whether you are a child or an adult you are as susceptible to the damage done to skin and soft tissue by hard activities as anybody else. So what can you look for if you decide have a day outdoors and face the dangers that you will come across that want to leave you bruised ,scratched, scraped, cut and itching from all the falls, knocks, stings and bites that most people experience when they are more used to spending their time indoors? Bruises are caused by a knock, and can happen without you even being aware of it. The blood vessels get damaged and leak. If you notice it right away, you can lessen the degree of bruising by applying ice or cold water to constrict the capillaries and cut down the flow of blood leaking from them. Some people bruise easier than others, and excessive bruising for no apparent reason could be a symptom of a more serious underlying condition and you should see your doctor. A bump, or lump, can appear for many reasons, but generally settles down after a while. It can simply be the body's reaction to a hard knock that did not damage the blood vessels, but prompted a natural swelling to protect the area. They can also be caused by insect bites. You don’t always see these little pests – they have lunch then zip off without you even being aware of it until the area begins to itch and swell. However, if you have a lump under the armpit, in your neck or behind your ears it could be a swollen gland and you should contact your physician. Everybody gets minor scrapes now and again, and when you spend any time outside you can get bitten by insects such as mosquitoes, midges, blackflies, horse flies – you name it, they will lunch on you as on any other animals. You can also get stung by vegetable nasties, though if you do then look around for a remedy. Strangely, many stinging plants have another plant close by that can be used as a remedy. This is likely because, after being stung, people just rubbed whatever was handy on the area and eventually these remedies were discovered. Thus, dock leaves are often found beside nettles, and touch-me-not beside poison ivy. These are good natural remedies for stings caused through contact with these particular plants, and there are many other natural remedies that can be used for the other everyday hurts that people receive just for carrying out normal activities outside in a natural environment. Let’s have a look at some of the natural remedies that people have used through the ages, and that are still used to this day, even in proprietary creams and salves. Calendula, or marigold, is very effective in relieving skin irritations and inflammation. It can be applied topically to relieve the symptoms of bruises, cuts and scrapes, and also for the initial treatment of burns and scalds. It has anti-inflammatory properties and can be used on inflamed or infected cuts and skin lesions. These properties are believed to be due to the high level of flavonoids found in calendula that have anti-oxidant properties and help the immune function to do its work. Among these is the powerful Quercetin with its strong anti-histamine properties. It also appears to possess anti-viral properties, though the reason for this is not clear and is still under investigation. Marigold also contains carotenoids and triterpene saponins, both of which will contribute to the medicinal effects. The dried flowers or leaves, or the fresh flowers, can be used and it is an old adage that pus will not form where marigold is used. It is also good for the treatment of insect bites and boils, where it appears to either prevent infection or clear up any that are there. It has also been proven to prevent the seeping of blood from the capillaries in scrapes, and to promote blood clotting. Calendula was used during the First World War by British doctors to dress wounds and prevent infection. A dressing steeped in a mild solution of calendula extract was enough, and it likely saved many lives. Another plant with similar properties is the alpine Arnica, which is useful to reduce the swelling and pain of bruises. It works simply by rubbing the leaves on the area when you have a fall or a hard knock. The active ingredients here are again flavonoids, and sesquiterpene lactones along with tannins, carotenoids and thymol. These, along with the flavonoids, stimulate the circulation and carry away any fluids trapped in bruises and swellings. The sesquiterpene lactones act as anti-inflammatories and boost the immune system, helping to reduce swelling and pain. In fact terpenoid chemicals are common to many of the herbs and flowers that have found a use in the relief of pain in swelling and bruises. The same is true of Ledum, better known as Rosemary, traditionally used for the treatment of burns, ulcers dandruff, and dry skin and to get rid of lice among many other internal and topical applications. The active ingredients of rosemary (ledum) include mono-, di- and triterpenes and also the ubiquitous flavonoids and camphor and linalool. If you wash down burns, grazes and cuts with a wash of ledum extract, then you will protect the patient from infection at the time when they are most vulnerable to infectious agents. Hypericum has uses as an anti-inflammatory and antiseptic, and is therefore useful for exactly the same conditions as all of the above. It also has astringent properties, so that like Calendula, Hypericum can be used to prevent the capillary seepage that frequently leads to infections. The active ingredients here are apparently flavonoids again, with their antiseptic and anti-inflammatory properties. Considering that they are among the most common antioxidants and anti-inflammatory agents in the plant world; it is no coincidence that flavonoids just happen to be contained in the vast majority of natural treatments for scratches, grazes and bruises. They reduce swelling, pain and inflammation, and also act as antiseptics by disrupting the cell walls of bacteria. Hypericum is well known by its alternative name St. John’s Wort, where it is used in the treatment of depression. However, the active ingredients here are mainly hyperforin and hypericin, which have little to do with the topical benefits of the plant. If you have suffered from insect bites and stings, then you would have been thankful had you brought some Apis Mellifica with you. Obtained from bees, this again contains terpenes among many other chemicals, and is used paradoxically in the treatment of bee stings and other insect stings and bites. It’s amazing how many of these old remedies contain terpenes of various types and also flavonoid chemicals. It is useful for most rashes that have raised puffy lumps, such as hives. Finally, if you manage to stay out without getting any bruises, abrasions, scratches or bites, you will be very lucky. However, if you get sunburn through being out in the sun too long, just look around for some stinging nettle, or Urtica. The leaf contains polysaccharides and lectins that stop the production of prostaglandins in the body that cause inflammation. Your sunburn will ease and you be able to return home relatively symptom free from your day outdoors. These natural remedies can be hard to find growing naturally due to many factors such as the time of year or your geographical location these herbs may grow in. Alternative sources are available at your local health food store where you can find all the above mentioned herbs in ointments and creams specifically formulated for your needs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1624) St. John’s Wort and HIV suppression
Date:
December 15, 2005 10:55 AM
St. John’s Wort and HIV suppression A study published online in Oct. 27th issue of Gene Therapy found that protein extracted from St. John’s wort (Hypericum perforatum) suppresses HIV-1 expression and inhibits its replication. Kamel Khalili, Ph.D., and researchers at Temple University school of Medicine’s department of neuroscience and Center for Neurovirology made the discovery while studying the effect of St. John’s wort extracts on cell growth and the behavior of brain cells in vitro. However, the researchers caution that the protein studied (named p27SJ) may not be present in the St.John’s wort available in supplement form. “We don’t know yet how we have to deliver the protein to cells infected with HIV-1,” Khalili said. “Even if the protein were present in the tablets, we don’t know how much might be present and whether the protein would be effective when ingested.”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1015) References
Date:
July 15, 2005 09:52 AM
ENDNOTES
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=637) SAFETY
Date:
July 15, 2005 09:34 AM
SAFETY Though research is still ongoing as to the specific actions of St. John’s wort and its constituents, it has been established that St. John’s wort is quite safe, especially when used as directed. Various studies back up the plant’s therapeutic properties and safe use, as well as provide technical information as to what makes St. John’s wort function. A 1994 study gives very technical information as to how hypericin works and the optimal methods of extraction, concentration and storage.25 There have been reports of phototoxicity in animals when taken in extremely large doses, and long-term studies are relatively few in number, but the overall consensus seems to be that Hypericum is a safe and effective medicinal herb.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=635) BLOOD TRANSFUSIONS
Date:
July 15, 2005 09:33 AM
BLOOD TRANSFUSIONS With the increasing rates of several blood-carried diseases (like AIDS), blood transfusion and blood donation rates are declining. Ensuring that donated blood is not “contaminated” by disease dictates that fewer people can donate blood, while fear of being contaminated by blood tainted by blood usually dissuades physicians from requiring blood transfusions unless absolutely necessary. Finding some sort of treatment of tainted blood would not only save money and time, but also calm fears about the possibility of being infected with a potentially serious disease through a blood transfusion. Hypericum is showing great promise in being able to treat blood contaminated by viruses. A recent Transfusion study states, Since hypericin is devoid of adverse action in most blood components and blood analyses, it is investigated as an additive with potential to inactivate infective viruses in blood components intended for transfusion. . . . Complete inactivation of 10 (6) tissue culture-infective doses of human immunodeficiency virus was obtained in whole blood and in diluted packed red cells after illumination with fluorescent light for 1 hour. Loss of viral infectivity to cultured CEM cells has been monitored by use of a detection assay for human immunodeficiency virus p55 in enzyme-linked immunosorbent assay and cytopathic assays. In physiologic media, hypericin interacts with albumin and lipoproteins, retaining the virucidal activity in bound form. . . . The apparent transfusibility of hypericin, taken together with the efficacy of the virucidal activity, the broad range of enveloped viruses affected, and the absence of adverse effects on stored red cells, may render hypericin useful for inactivation of infectious viruses in red cells.24
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=634) CANCER/TUMORS AND ST. JOHN'S WORT
Date:
July 15, 2005 09:31 AM
CANCER/TUMORS St. John’s wort, and more specifically, hypericin, has an outstanding ability to work favorably at the cell level against normally destructive invaders like viruses and bacterias. But these are not the only destructive agents that are being targeted by researchers in Hypericum research. Hypericin has been shown in various recent studies to work very effectively against cancerous cells and tumors of varying kinds. The April 1996 issue of Laryngyscope reported that hypericin is showing great potential in targeting human cancer growths through what is called “phototargeting,” a process that uses laser activation of hypericin, along with chemotherapy, for improved results in inhibiting the growth of cancerous cells. The study states, These results show that hypericin is a sensitive agent for phototherapy of human cancer cells in vitro and indicate that this drug may be useful for tumor targeting via minimally invasive imaging-guided laser fiber optics.22 Another recent study commented on the use of hypericin in treating human cancer cells, saying that “the nucleus of the cell . . . is the target for the toxic action of hypericin.” The study pointed out that the compound is well distributed throughout the cells, indicating that its value as an anticancer agent remains high.23 Yet another study points to the photodynamic qualities of hypericin in combating cancerous cells. The study’s results suggest that hypericin “has considerable potential for use as a sensitizer in the PDT [photodynamic therapy] of cancer.” And when hypericin was used in conjunction with other “scavenging” agents, its inhibitory abilities were greatly enhanced. Again, with such promising results from clinical studies, St. John’s wort (and hypericin) is perhaps opening the way to curing one of our most devastating diseases, cancer. Further research could quickly finalize a cure.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=633) SLEEP DISORDERS AND ST.JOHN'S WORT
Date:
July 15, 2005 09:28 AM
SLEEP DISORDERS Among the many ailments that often accompany middle and old age are various sleep disorders: insomnia, intermittent waking, sleep duration, and an overall poor sleep quality. The medical world has produced numerous synthetic drugs to deal with these disorders; however, most aren’t completely effective and produce undesirable side effects as well. Recent research suggests that St. John’s wort may be able to improve one’s sleep, especially that of older persons. A 1994 double-blind, placebo-controlled study published in the Journal of Geriatric Psychiatry and Neurology showed that Hypericum extracts gave the benefit of increased deep sleep during the total sleeping period of the patients. It explains, A hypostatic influence of the REM sleep phases, which is typical for tricyclic antidepressants and MAO inhibitors, could not be shown for this phytopharmacon [Hypericum]. Instead, LI 160 [Hypericum] induced an increase of deep sleep during the total sleeping period. This could be shown consistently in the visual analysis of the sleeping phases 3 and 4, as well as in the automatic analysis of slow-wave EEG activities. The study also makes an interesting connection between sleep and depression; that being many standard antidepressants and MAO inhibitors used to treat people who suffer from depression cause a decrease in deep sleep. As discussed earlier, St. John’s wort has shown great promise in treating depressed persons. So, besides helping people with sleep disorders, when used as an antidepressant, it gives antidepressant properties without the side effect of decreased deep sleep.21 This is certainly another valuable quality St. John’s wort has shown to possess.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=631) ST. JOHN’S WORT AND AIDS/HIV
Date:
July 15, 2005 09:28 AM
ST. JOHN’S WORT AND AIDS/HIV In 1991, some of the first work focusing on St. John’s wort’s effects on AIDS and the HIV virus began. Science magazine reported on the first study using the isolated hypericin, a key compound in Hypericum.16 Fred Valentine and Howard Hochster, researchers at New York University Medical Center, began one of the first studies looking at how hypericin can help uninfected T-cells from being infected with the AIDS virus in a cell culture. Their focus was on hypericin because it is a virucidal agent, meaning it can precisely target new virus particles and prevent them from infecting other cells. The only two drugs at that time approved for treating HIV infection—AZT and ddI—work by interfering with the key viral enzyme, reverse transcriptase. Since hypericin works more effectively than many drugs in regards to the reverse transcriptase phase, and since many animal tests have shown that it has low toxicity at therapeutic doses, researchers (including Valentine and Hochster) began these studies largely hoping that not only would hypericin work on its own, but that it would have a sort of synergistic effect when used with either AZT or ddI. 17 Additional studies are pointing to St. John’s wort, and more so, hypericin, as having great potential in treating HIV. Acosta and Fletcher recently detailed the processes in which the human immunodeficiency virus works to infect human cells, and point out that hypericin is at least somewhat effective in inhibiting the four main phases of virus “growth”— binding and entry, reverse transcriptase, transcription and translation, and viral maturation and budding (the researchers note that hypericin is especially effective in binding and entry, the first phase.) This denotes that hypericin could eventually have special importance in completely stifling the development of the growth of any virus, and most importantly, that of the HIV virus.18 Another study assessing the use and attitudes of HIV sufferers concerning the use of more alternative treatments for the virus as opposed to clinical drug therapies showed both an extensive use of unconventional therapies and a very favorable response to using the alternative treatments, which, of course, St. John’s wort was among. “Participants at all sites expressed positive views upon increasing unconventional remedies.”19 The fact is that the world of synthetic medicines has been basically ineffective in not only treating and relieving the symptoms of AIDS, but also in finding a cure for the dreaded disease. Sufferers are giving alternative therapies a try, and the results are very promising. A 1995 review appearing in Photochemisty-Photobiology treated the photodynamic properties of both hypericin and the structurally related hypocrellins for their anticancer and antiviral properties (especially the anti-human immunodeficiency virus). This article states that the promising anticancer and antiviral results obtained both in vitro and in vivo [in differing studies] have led to intensive investigation into their photo-physical and photochemical processes, especially kinetic studies of their intramolecular proton transfer . . . The biomedical advances of hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericin.20 Another study published in the September 1994 issue of Photochemistry-Photobiology gave hypericin the upper hand over the hypocrellins in treating HIV. Just one more vote in favor of promoting the use of St. John’s wort, and more specifically, hypericin, for use in treating HIV and in overall clinical medicine.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=630) RECENT RESEARCH
Date:
July 15, 2005 09:16 AM
RECENT RESEARCH A recent study (August, 1996) exploring the effect of Hypericum perforatum on depression re vealed some fairly stunning results. The British Medical Jo u rn a l published the results of one major studies, which consisted of twenty - three randomized trials, including a total of 1757 outpatients with mainly mild or moderately seve re depressive disorders. Testing was conducted with single preparations and combinations of extracts of the plant, and with placebo and anther drug treatment. As just mentioned, the results were very promising. In all aspects of the study, Hypericum extracts were shown to be “significantly superior” to placebo and similarly effective as standard antidepressants. There were nearly twice the number, percentage-wise, of dropouts due to side effects from the standard drugs than those taking the Hypericum extracts. Side effects occurred in eighty-four patients using standard antidepressants, while only fifty patients taking the Hypericum extracts experienced side effects. And the scores on the Hamilton depression scale, which measures severity of one’s depression, showed those taking Hypericum treatments scored slightly higher than those taking the standard antidepressant and significantly higher than those taking the placebo. 9 This study provides some firm ground for St. John’s wort to stand on in the treatment of depression, both in sheer numbers and its quality of treatment. Another contemporary study, carried out in 1995 by Witte, et. al, showed the Linde study to be accurate in its findings. This particular study, carried out as a multicenter, placebo-controlled double-blind trial, used a highly concentrated Hypericum preparation to treat ninety-seven outpatients. The course of the illness was assessed with the Hamilton Depression Scale, the von Zerssen Depressivity Scale and the Clinical Global Impression Scale. The authors of the study noted this in their abstract: Treatment resulted in an appreciable improvement in the symptoms of depression, and the seventy percent response rate (n=43) corresponded to that of chemical antidepressants. The preparation also showed an anxiolytic effect. The substance [Hypericum] was extremely well tolerated, and no side effects were reported by any of the patients.10 Again, this study’s findings correlate that of the Linde and other studies in that treatment with Hypericum is at least as effective as standard synthetic antidepressants without producing near the number of side effects. The Nursing Times also reported on recent findings dealing with Hypericum’s effect on depression. Stating that psychiatric medications are notorious for their undesirable side effects, and that the need for safer antidepressants is widely acknowledged, the blurb refers to a double-blind study, done by G. Harrer and H. Sommer (published in Phytomedicine, 1994 (1): 3-8), using St. John’s wort on 105 patients experiencing mild to moderate depression. They were aged twenty to sixty-four and had diagnoses of “neurotic depression or temporary depressive mood.” Patients were divided into two groups and monitored over four weeks, with one group receiving 300 mg of Hypericum extract three times daily and the other group receiving a placebo. All patients received psychiatric evaluations before the start of the study and after two and four weeks of treatment.11 The results of the study support the findings of other recent studies dealing with Hypericum and depression: 67 percent of the Hypericum group had responded positively to the treatment without any adverse side effects, whereas only 28 percent of the placebo group displayed any improvement. Harrer and Sommer state that the patients treated were experiencing strictly mild forms of depression; combining this with the study’s results and the results of other studies suggest that Hypericum treatment can be a very effective treatment for mild to moderate depression without severe side effects. The authors themselves even recommended that Hypericum should be considered as a remedy of choice. 12 These and other studies point to the strong possibility of using St. John’s wort, and specifically hypericin, on a wide scale to treat various forms of depression. Linde’s study suggests that St. John’s wort may have its most valuable asset in that of few or no side effects, something many sufferers of depression are very concerned about. The authors do note, however, that more research is necessary, especially in determining the severity and nature of depression, length of treatment, treatment dosage, preparation of Hypericum extracts, and occurrence of long-term side effects. Nevertheless, the results of this study and others are extremely promising for the millions of those who suffer from depression.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=627) DEPRESSION—STANDARD AND ALTERNATIVE TREATMENTS
Date:
July 15, 2005 09:13 AM
DEPRESSION—STANDARD AND ALTERNATIVE TREATMENTS Depression is a commonly occurring disorder; according to one recently published report, it affects nearly 17 percent of all Americans for the length of their lives.7 Because depression often involves a complex mixture of severity, length, and mode of treatment, it is often a difficult decision for doctors and patients alike to decide how to treat the depression. Many practitioners and patients are reluctant to use antidepressant drugs because of associated side effects. It seems logical, then that any additional forms of treatment with little risk, credible benefit, and moderate cost would be a useful addition to depression management. Extracts of St. John’s wort have long been used in “folk” medicine for a range of symptoms and problems, including mood and depression disorders. Extracts of St. John’s wort are licensed in Germany for the treatment of “anxiety and depressive and sleep disorders.” In 1993, more than 2.7 mil-lion prescriptions of Hypericum were counted in the seven most popular preparations in Germany.8 In the past ten years, several randomized clinical trials have compared the effects of pharmaceutical preparations of Hypericum with placebo and common antidepressants, with nearly all showing favorable practical application of Hypericum treatments for depression and other related disorders.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=626) HYPERICIN
Date:
July 14, 2005 10:46 PM
HYPERICIN One of the reasons St. John’s wort is attracting so much interest is because of one of its compounds, hypericin. The journal Photochemistry-Photobiology recently published a review of hypericins and the structurally related hypocrellins, giving a favorable outline of the various recent breakthroughs in medicine using these two compounds. The review states, Hypocrellins and hypericins, structurally related plant pigments isolated from Hypocrella bambuase and Hypericum respectively, are known photodynamic agents. This review summarizes certain significant advances in the phtotophysics, photochemistry and photobiology of these pigments in the last two years and discusses their prospects as novel therapeutic and diagnostic agents in the future . . . In particular, substantial progress has been made in both anticancer and antiviral applications (especially anti-human immunodeficiency virus). . . . The biomedical advances of hypocrellins and hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericins.2 The compound hypericin was isolated from St. John’s wort in 1942 and has been used as an anti-depressant and mood stabilizer for emotionally and mentally disturbed people. Among its many beneficial qualities is that of increasing blood flow to stressed tissue, thereby having a tranquilizing effect. It also reduces the fragility of capillaries and enhances uterine muscle tone because of its ability to increase blood flow.3 It is this compound that is being extensively researched for its possible therapeutic properties for a variety of diseases, mainly depression, AIDS and other viruses, cancer and sleep disorders. Extensive research has been done, especially recently, to determine exactly how hypericin works in treating these and other disorders. Nearly all the researchers are saying the same thing—that Hypericum (and specifically hypericin) promises significant value to the medical world in overcoming these serious disorders. The following sections discuss the various disorders that are being researched in conjunction with Hypericum/ hypericin therapy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=623) ST. JOHN’S WORT (Hypericum perforatum)
Date:
July 14, 2005 10:42 PM
Overview St. John’s wort (Hypericum perforatum) belongs to the family Hypericaceae, which consists of eight genuses and about 350 species. St. John’s wort is a plant whose leaves are whorled, gland-dotted, simple, and usually smooth-margined. Its flowers are five-petalled and yellow with many stamens, which are often united in bundles. St. John’s wort was first known to be used in the Crusades to treat battle wounds. Contemporary research supports this, with various diseases proving Hypericum’s worth in aiding all types of topical wounds in their healing and recovery. It is specifically used for putrid leg ulcers that are difficult to heal, and is used to treat many varying septic wounds, boils, and inflammation in cellulite and lymphangitis.1 For centuries, St. John’s wort has been used to treat disor-ders of mood and temperament.” Modern research is also backing this up, with several very recent studies demonstrating St. John’s wort’s ability to treat mild and moderate forms of depression as well and with fewer side effects as the standard antidepressant drugs used. Recent investigation is also revealing St. John’s wort to be helpful for a number of other disorders. Among them is AIDS/HIV, a disease that leads several age/gender groups in cause of death. But St. John’s wort is being researched for its ability to hinder viral growth and production, perhaps making it key to at least treating the virus, if not able to cure the disease. Hypericum is being used for treatment research of several other virus-caused diseases as well. Another area in which St. John’s wort is showing great promise is that of cancer. Various forms of cancers and growths have been successfully treated with therapies including Hypericum or hypericin (one of its compounds). And the list goes on and on. St. John’s wort is certainly an herb worth investigating for its seeming abilities to combat various disorders prevalent among us.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=622) Depression
Date:
June 30, 2005 09:20 AM
Depression By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Depression is a widespread health imbalance that effects many people at some point in their lives, and may be caused by a multifaceted list of factors. Depression can be triggered by personal tragedy, loss of a loved one, or changes in life situations (even if they are positive!). Some of the less recognized causes of depression may involve diet, including over-consumption of sugar, artificial sweeteners, chemical flavorings and preservatives, insufficient nutrition and foods that causes an allergic or sensitivity reaction in an individual. Lack of exercise and not enough sunlight, (i.e. Seasonal Affective Disorder), may be implicated as well. It is essential that those suffering from severe depression seek professional care. Since depression can arise from many different sources and operate on multiple levels, it is helpful to remember that “true healing” requires one to explore and address the root cause(s), not just attempt to cover up the symptom. Proper nutrition is essential. B vitamins can be helpful, such as Nature’s Answer’s B-Stress with Herbs, along with other nutrients such as the amino acids, GABA (particularly for anxiety), Tyrosine and Phenylalanine. Regular exercise, and a nice relaxing bath in lavender oil and sea salt are also enjoyable aids for lifting one’s spirits. Herbs can be useful in relieving the symptoms of mild to moderate depression. Nature’s Answer offers many high-quality, single herb and combination formulas (liquid or capsule) that feature ingredients well-known for balancing emotional mood. Relora®* features a patented propriety blend of two herbs, Magnolia (standardized to 1.5% honokiol (3.75mg)) and Phellodendron (standardized to 0.1% berberine (0.25mg)) which, when combined according to a particular method, may help reduce the negative effects of stress, a factor that leads to depression as well as “stress overeating”. When the body is under stress, it causes the release of specific “stress hormones” that influence mood and emotional well-being. Relora® is unique because its active plant constituents work on the body’s natural chemistry to re-establish a normal equilibrium of stress hormones, while enhancing feelings of relaxation and cheerful outlook. Another powerful, “all-in-one” proprietary herbal blend formula from Nature’s Answer® is Mood Balance 2™ (alcohol free liquid, vegetarian capsule). Mood Balance 2™ contains key ingredients well-recognized for their beneficial actions on emotional health, including St. John’s Wort, California Spikenard, Gotu Kola, Skullcap and Eleuthero root**. This combination of ingredients can help “lift the spirits”. (Note that these herbs are also available from Nature’s Answer® as single herb formulas in concentrated liquid herbal extracts and/or vegetarian capsules; Kosher). Key ingredients in Mood Balance 2™include: St. John’s Wort (Hypericum perforatum), used for a range of nerve disorders and said to “chase away evil spirits.” Since 1996, it has become one of the most popular herbs in the US due to its use as a mild to moderate antidepressant. A number of current studies confirm its effectiveness, including a review in the British Medical Journal of 23 clinical trials, which reported that it worked nearly as well as the leading pharmaceuticals with far fewer side effects. Although more research is needed, it appears that the activity of St. John’s Wort is due to a variety of naturally occurring components, including Hypericin and Hyperforin. Nature’s Answer’s exclusive formula, Super St. John’s Wort (vegetarian capsule), is standardized to both 3.0% hyperforin and 0.3% hypericin. Gotu Kola (Centella asiatica), used for centuries in Ayurvedic medicine as a nerve tonic and to treat emotional upset, insomnia, stress, anxiety and memory problems. It is currently used along with meditation and yoga due to its abilities to both calm and energize nerves. Skullcap (Scutellaria lateriflora) has the double action of relaxing nervous tension while building the central nervous system. As a mild bitter it will also help stimulate digestion and help the liver. Eleuthero root** (Eleutherococcus senticosus) is an “adaptogen” that helps to balance the entire system. It gives strength and fortitude, especially when dealing with stress; so often a factor in depression.
References for Educational Purposes:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=537) Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.
Date:
June 29, 2005 09:37 AM
Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support. In our high-powered world, countless Americans are searching for a wholesome, natural product to help them maintain a positive outlook and sense of well-being. The remarkable botanical, St. John’s wort, is well-known for its established history of safe use. Now Source Naturals offers you the first and only once-daily, TIMED-RELEASE ST. JOHN’S WORT. This premium botanical is manufactured in a special cellulose base, which is tested to release St. John’s wort over a 12-hour period. Source Naturals tests each production lot of TIMED-RELEASE ST. JOHN’SWORT. This exclusive supplement is standardized to 0.3% hypericin, yielding 2.7 mg in every convenient daily dose— the amount shown in research to support mild to moderate maintenance of a positive mood. At a time when our emotional well-being is challenged by unprecedented stress levels, research into the most convenient and effective natural remedies is critical. Source Naturals is your connection to this research, dedicated to quickly bringing you the benefts of the latest emerging wellness strategies. Popular Choice For a Positive Mood—Now Even Better! St. John’s wort, or Hypericum perforatum, has been valued by diverse cultures as far back as the Middle Ages for its ability to support a positive outlook and sense of well-being. Today modern consumers are experiencing the benefits of this renowned herb, which include mood-brightening, relaxation, alertness, and a sense of overall well-being. Unlike other supplements on the market, Source Naturals TIMED-RELEASE ST. JOHN’SWORT is produced using the most advanced scientific methods. The result is a supplement that offers the once-daily convenience today’s consumers have come to expect. Clinical Trials A review of 23 randomized clinical trials encompassing 1757 subjects was reported in the British Medical Journal. It showed that St. John’s wort was more effective than placebo for mild to moderate maintenance of a positive mental outlook. The Beneficial Constituents The beneficial constituents of the St. John’s Wort plant are believed to be the naphthodianthrones, especially hypericin and pseudohypericin, and a wide variety of flavonoids. Source Naturals TIMED-RELEASE ST. JOHN’S WORT is standardized to consistently yield 0.3% hypericin. Each convenient once-daily dose contains 900 mg of St. John’s Wort extract, yielding 2.7 mg hypericin. This is the optimal amount found in most studies to support a positive outlook and sense of wellbeing. Benefits may be experienced within 4 to 6 weeks of initial use. Emotional Well-Being: Important Component of the Wellness Revolution Source Naturals is pleased to join with your local health food store in offering you the next generation in St. John’s wort supplementation. TIMED RELEASE ST. JOHN’SWORT can help you support a positive mood with the remarkable properties of the plant world, exclusively formulated for once-daily convenience. This advanced product reflects today’s revolution in natural health care, offering you the benefits of natural, cuttingedge supplementation.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=515) Defeat Depression
Date:
June 13, 2005 01:18 PM
Defeat Depression by Cal Orey Energy Times, August 2, 1999 Depression plagues the creative and the mundane. The disparate desperate driven to distress by depression include painters, poets, actors and musicians as well as truck drivers, clerks, electricians and physicists. The victim list encompasses Vincent van Gogh, Emily Dickinson, Audrey Hepburn, Virginia Woolf and Ludwig von Beethoven, as well as millions of other sharers of melancholy misery. More than 17 million American men and women experience depression in one form or another every year, according to the National Mental Health Association (NMHA) in Alexandria, Virginia. This includes the deeply destructive major, or clinical, depression, the wide mood swings of bipolar disorder (manic-depressive illness), and dysthymia, a milder, long-lasting form of emotional suffering. Twice as Many Women In the depression scenario, women suffer twice as much: Two times as many women as men endure clinical depression, reports the NMHA. The mood-deteriorating effects of the hormonal disruptions women are heir to may be partly to blame. According to the National Institute of Mental Health (NIMH), about one of 10 Americans wades through at least one depressive swamp sometime during his or her life. The good news: Research shows that diet and lifestyle can lower your risk of depression. Birth of the Blues Nowadays, mounting evidence suggests that depression may result more from physiological factors than psychological woes. Some of the hidden reasons why you may be depressed include: nutritional deficiencies, exacerbated by overdosing on too much caffeine, sugar, alcohol and high fat foods; allergies; anxiety and chronic stress; and a chemical imbalance in the brain's gray matter. According to the NMHA, people with depression often possess too little or too large a quantity of the neurotransmitters norepinephrine, serotonin and dopamine. Changes in levels of these brain chemicals may cause, or contribute to, clinical depression. The NMHA also reports that an imbalance of melatonin, a chemical made by the body's pineal gland (located at the base of the brain), contributes to a form of wintertime depression called seasonal affective disorder (SAD). This hormone is made at increased levels in the dark. Therefore, the body may oversupply this hormone during winter's shortened daylight hours. Plan B Since the B vitamins are often involved in the production of energy, and a large component of depression may encompass the inability to get out of bed and deal with the world, experts believe that at least some of the signs of depression are linked to B deficiencies. For instance, studies cited in the Encyclopedia of Natural Medicine (Prima) by Michael Murray, ND and Joseph Pizzorno, ND, demonstrate that folate deficiency and lack of vitamin B12 can compromise mental health (Drugs 45, 1993: 623-36; Lancet 336, 1990: 392-5). Inositol: This vitamin is also part of the B vitamin complex, and it, too, has shown its ability to lift spirits. Research work in Israel shows that daily inositol given to 28 depressed patients for four weeks produced an overall positive effect. (Eur Neuropsychopharmacol 7:2, May 1997: 147-55). Inositol is found in whole, unprocessed grains, citrus fruits (except lemons) and brewer's yeast. NADH: Allan Magaziner, DO, in his book The Idiot's Complete Guide To Living Longer & Healthier (Alpha), reports that brain energizing NADH, a metabolite of vitamin B3, enhances the production of the key neurotransmitters dopamine, noradrenaline and serotonin. "In a recent clinical trial," he claims, "nearly all patients given NADH for depression reported improvement in their symptoms and the absence of side effects or adverse reactions." Moody Spotlight Another substance winning the spotlight for its effect on mood is SAM-e: S-adenosylmethionine. In New York on February 24, a symposium coordinated by the American Health Foundation met to hear researchers present information from studies of SAM-e's ability to possibly ease depression. "SAM-e is a natural product. You and I have it but as people age it declines in production in the body. And that's why we believe supplementation in older people is a beneficial means of bringing that back up and helping people that have depression," said the lead symposium researcher, John H. Weisburger, PhD, MD, Director Emeritus, American Health Foundation in Valhalla, New York. Another researcher, Teodoro Bottiglieri, PhD, Associate Professor of Biomedical Studies and Neurology, Director of Neuropharmacology at Baylor University reported: "SAM-e has been shown to enhance brain dopamine and serotonin neurotransmitter metabolism and receptor function. It may also aid in the repair of myelin that surrounds nerve cells. These mechanisms are likely to be responsible for the antidepressant effect of SAM-e." (Bottiglieri is co-author with Richard Brown, MD, and Carol Colman of Stop Depression Now, a report on the powers of SAM-e just published by G.P. Putnam's Sons.) SAM-e was first touted as an antidepressant in Italy in 1973. It's been reported that nearly 40 clinical trials demonstrate its beneficial effects as a natural antidepressant. For instance, an analysis of more than 1000 people suffering depression showed that the effect of antidepressants in patients taking SAM-e was 17% to 38% better than dummy preparations. Conventional antidepressants show a 20% effectiveness rate (Bressa G. Acta Neurol Scand S154, 1994: 7-14). 5-HTP: Another popular supplement to boost mood and relieve depression is hydroxytryptophan. "This medication is actually a brain chemical that is metabolized from tryptophan into serotonin," says Magaziner. And since low serotonin levels have been linked with depression, and certain prescribed medications may up serotonin levels, 5-HTP is in demand. "One of the more impressive studies supporting the efficacy of 5-HTP for depression evaluated 100 people who had previously found conventional antidepressant therapy to be inadequate. Forty-three of these folks reported a complete recovery, and eight showed significant improvement," reports Magaziner. Not only has 5-HTP been shown to work slightly better than drugs known as SSRIs (these include Prozac), he adds, it has fewer side effects than standard antidepressants, too. DHEA: Medical experts also believe that levels of the hormone DHEA (dehydroepiandrosterone) may influence mood. Ray Sahelian, MD, in his book All About DHEA (Avery) reports an interesting study conducted by Dr. Owen Wolkowitz of the Department of Psychiatry, University of California, San Francisco. A group of six depressed middle-aged and elderly individuals who took DHEA found that within a month they had better memory and mood. (Biological Psychiatry 41, 1997: 311-18.) "In addition," adds Sahelian, "other studies have also found that DHEA increases energy levels and a sense of well being." But follow package directions: Some people complain of greater irritability and overstimulation with DHEA, when they take large amounts. Herbal Relief St. John's wort: still the most touted natural therapy for defeating depression. In Europe, 23 clinical studies, reviewed in the August 3, 1996 British Medical Journal, found that this herb, also known as Hypericum perforatum, can be helpful in alleviating cases of mild to moderate depression. The work, which included 757 patients, has shown that Hypericum produced fewer side effects than conventional anti-depressants. Although experts have never satisfactorily explained exactly how St. John's wort benefits the brain, some theorize that it boosts serotonin levels. And it can help SAD sufferers. "In a recent study of 20 people with SAD, four weeks' worth of St. John's wort significantly alleviated feelings of depression. Those people who added full-spectrum lights to the treatment program gained an even greater benefit," notes Dr. Magaziner. Valerian: Anxiety and stress, which can cause depression and insomnia, may be helped by this herb, says the prolific Dr. Sahelian in his book Kava: The Miracle Antianxiety Herb (St. Martin's). In 101 Medicinal Herbs (Interweave), Steven Foster reports that "Ten controlled clinical studies have been published on valerian...one of which suggests that valerian should be used for two to four weeks before daily mood and sleep patterns improve." Amino Acid Help Amino acids, the building blocks of protein, may also help improve mood. (For more on protein, see page 65.) These chemicals are used by the body to construct neurotransmitters, brain chemicals that facilitate mental activity. For instance, the amino acid L-tyrosine is necessary for the formation of transmitters adrenaline and dopamine. This substance, therefore, is given to alleviate depression and anxiety. The substance L-dopa which is given to victims of Parkinson's disease is concocted from tyrosine. And several antidepressants alleviate bad moods by boosting the interaction of brain chemicals related to tyrosine. In addition, since tyrosine is used to make adrenaline, this amino acid may be helpful for folks trying to cope with the mood problems related to stress. Another amino acid that experts believe useful for better moods, L-methionine, is used by the body to make choline, a crucial substance for brain function. (Choline goes into the formation of acetylcholine, a neurotransmitter.) Methionine has been given to people suffering from schizophrenia and depression as well as to those with Parkinson's. Methionine plays a number of crucial roles in the brain and body since it helps form other vital proteins. Depressive Smoking For those concerned about preserving a positive mood, researchers are positive that smoking worsens depression. A study at the Department of Behavioral Services at the Henry Ford Health System in Michigan found that daily smokers run twice the risk for major depression compared to those who only smoked occasionally. Unfortunately, the investigators found that not only did smoking seem to lead to depression, depression, in turn, led to more smoking (Archives of General Psychiatry, 2/99). "Smokers who have depression tend to see their smoking become a daily habit and it may be because they use nicotine to medicate their depressed mood," reported Naomi Breslau, PhD, who headed the research. Over a five year period, the researchers looked at about a thousand young people aged 21 to 30. They found that daily smokers generally start smoking in adolescence, and those who report early depression are three times as likely to eventually become daily smokers. If you're feeling down, don't give up hope. Although depression can prove to be a depressingly complicated malady, daily, healthy habits can offset its effects. Getting consistent exercise, dousing your cigarettes and turning to herbal and nutritional help to treat mild depression may defeat those blues.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=329) Herbs in Perspective
Date:
June 10, 2005 10:25 PM
Herbs in Perspective by Phyllis D. Light, RH-AHG Energy Times, June 16, 2004 "I don't claim a cure...I just try to give people some ease," noted Tommie Bass, a traditional Southern herbalist whose life has been the topic of several books, including Mountain Medicine by Darryl Patton (Natural Reader Press) and Trying to Give Ease by John Crellin and Jane Philpott (Duke University Press). That philosophy reflects the perspective embraced by herbalists for eons. The traditional use of herbs is incorporated into all cultures. Herbs were the first medicine and the origin of what we now call modern medicine. These plants have not been prescribed to conquer specific illnesses but instead nourish the body and aid in building overall health. Traditional Knowledge Observation, psychological need and human instinct form the foundation of traditional herbal knowledge and use. This knowledge has been passed down through generations based on practice and experience. The result: a depth of information about the safe and effective use of herbs that spans thousands of years. The goal of a traditional herbalist is to bring the body into balance (homeostasis), prevent disease and support immune functioning. Unfortunately, any kind of therapeutic knowledge can be misused, and that has happened with some herbs, causing some people to question herbal medicine's safety. As more people turn to natural therapies, scientists have begun to perform evidence-based research into their safe and effective use. The good news is that much of this research has validated the effectiveness of herbs and supplements. Echinacea to the Rescue Do the sniffling sneezes that herald a cold have you reaching for your bottle of echinacea? If so, you are in good company. Echinacea (Echinacea spp) is one of the top-selling herbs. The colorful American prairie plant was extremely popular during the early 1900s, until the use of modern antibiotics relegated it to the back shelf. But a resurgence of interest in herbs propelled echinacea back into the mainstream in the second half of the twentieth century. And this herb boasts an impressive body of research and has an excellent record of safety. For instance, researchers at Virginia Commonwealth University School of Pharmacy have found echinacea to be effective in supporting the body's defenses against upper respiratory tract infections and for reducing the duration of discomforts that accompany the common cold (Pharmacotherapy 2000; 20(6):690-7). Although studies have not confirmed its ability to prevent colds, echinacea is widely used by many folks for just that purpose. Researchers have found that echinacea's effectiveness may drop if you use it for eight straight weeks (Am J Health-Syst Pharm 1999; 56(2):121-2). So if you take it for a couple of months, take a couple of weeks off before using it again. Flower Power St. John's wort is another herb with ancient origins that has experienced a modern resurgence. Named after St. John the Baptist, St. John's wort (Hypericum perforatum) is generally in bright yellow bloom around St. John's Day (June 26). According to herbalist Michael Tierra, author of The Way of Herbs (Pocket Books), St. John's wort affects the liver and the nervous system. In 1984, the German Commission E, a recognized herbal authority, approved St. John's for depressive disorders, and in topical form for acute injuries and first-degree burns. Modern research has reaffirmed the use of St. John's wort in the short-term treatment of mild to moderate depression (Cochrane Review Issue 2, 2004). It has also been found to be useful in premenstrual depression (Int J Psy Med 2003; 33(3):295-7). (Researchers have found that the herb may alter how the body processes some prescription medications, so check with your healthcare provider before using such medicines along with St. John's wort.) King of Herbs " Ginseng (Panax) received the lofty title, King of Herbs, due to its reputation as a tonic and its ability to stimulate the body into healing," notes herbalism writer Darryl Patton. This plant was once so popular in China that it was worth its weight in gold. In fact, ginseng is the popular name for two different types of ginseng, American and Korean (Panax quinquefolium and P. ginseng). Both are considered adaptogens, or substances that help the body deal with stress more effectively. And modern research has found that ginseng can be used to improve overall energy and vitality, and to help the body deal more effectively with chronic stress (J Pharm Sci 2003 Dec: 93(4):458-64). Researchers have found that ginseng helps boost the immune system (J Med Food 2004 Spring; 7(1):1-6). This ancient herb is also a powerful antioxidant that confers protection on the heart (Biochem Biophys Acta 2004 Feb 24; 1670(3):165-71). In other studies, ginseng has been found to reduce symptoms of menopause, improve endurance and lower blood sugar levels. To avoid overharvesting wild ginseng, most of the herb on the market is now grown on farms. Ode to Ginkgo Known as the Living Fossil, ginkgo is the oldest known plant in the world. A native of Asia, ginkgo (Ginkgo biloba) is now found in many US cities, where it has been planted as a quick-growing shade tree. Traditionally, ginkgo was used for disorders and diseases of the lungs and the kidneys, as a remedy for bronchitis and to improve circulation in older people. Ginkgo contains substances that act as potent antioxidants by scavenging cell-damaging free radicals, and it is thought to help reduce the risk of disease. By opening capillaries, ginkgo increases circulation, and enables nutrients and oxygen to move around the body, especially to the extremities. Indeed, recent research indicates that ginkgo may ease pain associated with arterial disease in the legs (Am J Med 2000; 108:276-81). Other studies support the use of ginkgo for acute stress (J Pharm Sci 2003 Dec; 93(4):458-64) and some cases of hearing loss (Acta Otolaryngol 2001; 121:579-84). In a UCLA Neuropsychiatric Institute study on ginkgo, researchers found significant improvement in the verbal recall of people who had age-related memory problems. According to Dr. Linda Ercoli, lead author of the study, "Our findings suggest intriguing avenues for future study...with a larger sample to better measure and understand the impact of ginkgo on brain metabolism." Tasty Ginger Traditionally, fiery ginger (Zingiber officinale) has been used to aid digestion, reduce nausea, relieve gas, reduce symptoms of arthritis and strengthen the heart. Modern researchers have started to validate these traditional uses; ginger has reduced the nausea and vomiting of morning sickness in studies (Aust NZJ Obstet Gynaecol 2003 Apr; 4392:139-44). Meanwhile, researchers at the University of Minnesota have applied for a patent on a substance found in ginger, believing it to have anticancer activity. According to Ann Bode, "Plants of the ginger family have been credited with therapeutic and preventive powers and have been reported to have anticancer activity." Ginger can be found in natural food stores as fresh or dried root. It often appears in small amounts in herbal formulas as a carrier herb-one that helps move other herbs around the body. The best medicine combines the health support of herbs with the scientific rigor of conventional medicine. And as scientists continue to search for new medicine from ancient remedies, we can enjoy the best of both perspectives.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=287) St. John's Wort Emotional Balance - The Natural Solution For Mental Well-Being
Date:
June 06, 2005 08:53 AM
Planetary Formulas ST. JOHN’S WORT EMOTIONAL BALANCE features the European botanical legend St. John’s wort (Hypericum perforatum). This traditional herb has long been known for supporting a positive mood and healthy outlook. These properties have now been confirmed by modern research. ST. JOHN’S WORT EMOTIONAL BALANCE combines St. John’s wort with classic Chinese and Western herbs to promote a balanced state of mental well-being. St. John’s Wort: Modern Clinical Research Most research into the properties of St. John’s wort has been conducted in Germany, where the use of this herb is widespread. The plant contains a number of important compounds including hypericin, pseudohypericin, hyperforin and a wide variety of flavonoids. Clinical interest in St. John’s wort reached new heights in 1996, when the British Medical Journal published a summary of research findings, concluding that it had a beneficial effect on mental well-being. Classic Chinese Herbs Blended with this key botanical are Chinese herbs drawn from the classic formula Xiao Yao Wan, or "Relaxed Wanderer," developed during the Song Dynasty (960-1279). These special herbs are bupleurum root, peony root, atractylodes root, dong quai root, poria cocos sclerotium, licorice root, cyperus rhizome and ginger root. This formula was created more than 300 years ago to promote a balanced state of mental well-being. Completing the blend is lemon balm (Melissa officinalis), historically used to raise spirits, as noted by Shakespeare’s, "Lemon balm doth make the heart merrieth." Formula by Michael Tierra These botanicals are only now being recognized by modern science as having those unique characteristics well-known to our ancestors. ST. JOHN’S WORT EMOTIONAL BALANCE has been created by the renowned clinical herbalist and licensed acupuncturist Michael Tierra. Over 30 years of herbal study led to his selecting the botanicals in this unique blend. Planetary Formulas now offers this herbal supplement, which integrates modern biochemistry with the classical wisdom of traditional Chinese and Western herbology. The result is a balanced and natural approach to mental well-being. Its unique properties offer an alert, clear and positive alternative to life’s often distressing circumstances.
References Also Available: Full SpectrumTM and Standardized St. John’s Wort Extract Tablets This blend combines a concentrated 600 mg of St. John’s wort extract standardized to 0.3% hypericin, the primary qualitative marker of St. John’s wort, with a concentrated flavonoid-rich extract (4:1) of St. John’s wort flowering tops. Combining the standardized hypericin extract with flowering top extract assures that all of the components naturally occurring in St. John’s wort are present. Also available are pure 300 mg St. John’s Wort extract tablets standardized to 0.3% hypericin. Full SpectrumTM St. John’s Wort Liquid Extract This Full SpectrumTM liquid extract is prepared in the same careful manner to capture the vital components of St. John’s wort, which are reflected in the rich burgundy color of the liquid.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=196) Diet Phen - Dietary Supplement and weight Loss ... 
Date:
June 01, 2005 12:36 PM
Getting slim, trim and fit is no easy task. To do it you need adequate Energy, Nutritional and Emotional Support, and a Positive Attitude. Source Naturals puts them all together in the DIET-PHEN Weight Loss Plan. The plan includes an herbal-safe nutrient formula that combines optimal amounts of St. John’s wort with synephrine and green tea extract, plus L-phenylalanine and chromium. Meet your weight loss goals the natural way. Try Source Naturals DIET-PHEN dietary supplement in conjunction with the Diet-Phen Weight Loss Plan. THE PLAN HELPS TO:
DIETING – It Starts in Your Head. Successful dieting depends on the right mind-set: you need a positive outlook and determination. When your head is in the right place, your body may follow. That’s why the DIET-PHEN Weight Loss Plan includes natural herbs and amino acids to help support a sense of active calm. ST. JOHN’S WORT – The CenterPeace of DIET-PHEN. In use since ancient times, Hypericum perforatum is a flowering herb highly valued for its positive influence on mental well-being. Known for its soothing effect, it seems to promote relaxation without drowsiness. Recent research has focused on the connection between hypericin (the principal phytochemical in St. John’s wort) and serotonin, a key neurotransmitter associated with mood. About 90% of your serotonin receptors are found in your brain’s emotional center, the limbic system. SYNEPHRINE, GREEN TEA AND L-PHENYLALANINE – Energize with an Attitude! Synephrine and green tea extract are added for that extra energy needed during dieting. The brain uses phenylalanine to manufacture dopamine and norepinephrine, two neurotransmitters that play an important role in drive and determination. ACETYL L-CARNITINE – Transporting Fat to the Furnace. Within each of your trillions of cells are thousands of tiny energy factories called mitochondria. They convert fats and sugars into metabolic energy. Acetyl L-carnitine supports this process by transporting fat molecules to the mitochondria. THE PLAN INCLUDES A DAILY SERVING OF 3 DIET-PHEN TABLETS TO PROVIDE:
GET STARTED WITH THE PLAN ! Get DIET-PHEN dietary supplements and the Weight Loss Plan at VitaNet health food store.
REFERENCES:
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Kava kava can be used to treat depression and anxiety, largely due its content of kavalactones that are believed to increase the amount of a number of neurotransmitters in the blood, including the feel-good neurotransmitter serotonin. 
Passion flower has been used for centuries to treat anxiety, stress and depression, its active ingredients believed to be maltol and ethylmaltol that help to increase the level of gamma-aminobutyric acid (GABA) in the brain. GABA is one of the brain's key neurotransmitters and has been described by some as the brain's own 'Valium' supply. 
