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Beta-alanine supplementation relieves fatigue, increases musclecarnosine Darrell Miller 5/2/19
A healthy gut is a more efficient gut: Prebiotic fiber found tobreak down a high-fat diet better, reducing accumulation and inflammation Darrell Miller 4/26/19
How to Manage Cholesterol Naturally Darrell Miller 4/4/17
What to eat: Broccoli vs. cauliflower - Bel Marra Health Darrell Miller 2/13/17
How nutritious are plant-based milks? Darrell Miller 12/3/16
Anti-Aging Powers of Broccoli Enzyme Darrell Miller 11/25/16
Benefits of Turbinado Sugar Darrell Miller 2/8/14
Difference between Vitamin B-12 Cobalamine Darrell Miller 1/6/14
What Is The Difference Between flaxseed oil and fish oil Darrell Miller 1/1/14
What are the health Benefits of Cod Liver Oil Darrell Miller 7/11/12
What Makes Neptune Krill Oil So Good For Your Health? Darrell Miller 3/24/12
What Are The Health Benefits Of L-Carnosine? Darrell Miller 2/28/12
What Form Of Calcium Is The Best Calcium? Darrell Miller 2/21/12
What Is The Difference Between DGL Licorice and Regular Licorice? Darrell Miller 2/13/12
Your Diet May Be What's Causing Your Acne Darrell Miller 9/19/11
How Does Progesterone Cream Help Ease Hot Flash Symptoms? Darrell Miller 6/21/11
Using SAMe for Depression Darrell Miller 6/4/11
Potassium: Cardiovascular Health, Muscle Function, Cellular Activity, And Blood pH Darrell Miller 5/11/11
Is Elderberry Good for Colds and Flu? Darrell Miller 4/14/11
How Does Boswellia Fight Inflammation? Darrell Miller 4/13/11
What is Oligonol Good for and How Does It Boost My Health? Darrell Miller 3/22/11
Is AHCC Good for the Immune System? How So? Darrell Miller 3/2/11
Horsetail Darrell Miller 8/31/09
Bee Pollen Darrell Miller 5/20/09
Herbs Darrell Miller 10/9/08
Wormwood, Black Walnut, Triphala Darrell Miller 6/17/08
Coral Calcium Darrell Miller 5/16/08
Ubiquinol Reduced CoQ10 Darrell Miller 4/7/08
Omega-3 Relieves Depression in Some Individuals Darrell Miller 11/2/07
Coconut Oil May Help Promote Healthy Thyroid and Digestive Function Darrell Miller 11/1/07
Ubiquinol Darrell Miller 10/24/07
Omnivore Vs Vegan Who Is Right? Darrell Miller 10/21/07
Pumpkin Seed Oil is good for your health Darrell Miller 10/14/07
Complete Liver Cleanse Darrell Miller 4/19/07
Supplements for Sexual health! Darrell Miller 4/17/07
EpiCore Benefits Darrell Miller 4/9/07
Peppermint Oil for IBS Darrell Miller 3/24/07
The Fizzy Comparison (Airborne Vs Wellness Fizz) Darrell Miller 2/26/07
Scientific References Darrell Miller 2/11/06
Olive Leaf Extract - for immune support Darrell Miller 1/2/06
Glucosamine & Chondroitin - JOINT HEALTH Darrell Miller 12/22/05
Pomeratrol™ Fact Sheet Darrell Miller 12/19/05
FRUCTOSE Darrell Miller 12/17/05
ERYTHRITOL Darrell Miller 12/17/05
Butterbur Extract Fact Sheet Darrell Miller 12/8/05
VitaBerry Plus+ Fact Sheet Darrell Miller 12/7/05
Utah's Inland Sea Minerals – Topical Application Darrell Miller 11/22/05
Research on SAMe.... Darrell Miller 10/26/05
Comprehensive Prostate Formula-the Clinical Studies Darrell Miller 10/13/05
Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of... Darrell Miller 7/27/05
Best Mangosteen 10% Extract with xanthone flavonoids Darrell Miller 7/27/05
SIDE EFFECTS OF SYNTHETIC PROGESTIN DRUGS Darrell Miller 7/25/05
References Darrell Miller 7/13/05
PYCNOGENOL - ITS REMARKABLE BENEFITS Darrell Miller 7/13/05
Pain - Post Op and Relaxation Darrell Miller 7/13/05
Quercetin and Bromelain - for better health. Darrell Miller 7/4/05
GLISODIN POWER - Superoxide Dismutase (SOD) Darrell Miller 6/29/05
Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support. Darrell Miller 6/29/05
ALPHA GPC - Improves Mental Performance Darrell Miller 6/28/05
REFERENCES Darrell Miller 6/25/05
CHITOSAN: The Fiber that Binds Fat Darrell Miller 6/25/05
Treating and Preventing Age-Related Mental Disorders Darrell Miller 6/25/05
GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient .... Darrell Miller 6/21/05
Building the Burn Darrell Miller 6/14/05
Truth in Labeling Darrell Miller 6/14/05
Power Meals - Shakes, smoothies and bars help make getting good nutrition easy. Darrell Miller 6/14/05
Winter Survival Kit Darrell Miller 6/13/05
Home on the Range Darrell Miller 6/13/05
ACTIVATED QUERCETIN: a truly hypoallergenic formula... Darrell Miller 5/31/05
Glycerylphosphorylcholine -- Supports Cognitive Function in AD ... Darrell Miller 5/24/05
L-Tryptophan 500mg Darrell Miller 5/13/05
Garlic Extract Modulation or Pulmonary Vascular Function: Darrell Miller 5/12/05
Nattokinase: Food For Cardiovascular Health Darrell Miller 5/10/05



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Beta-alanine supplementation relieves fatigue, increases musclecarnosine
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Date: May 02, 2019 03:37 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Beta-alanine supplementation relieves fatigue, increases musclecarnosine





It has been found in a study that supplementing with beta-alanine can increase muscle carnosine and relieve fatigue. The study was published in the journal Nutrition Research and the team looked at the effects of beta-alanine supplementation on performance, L-histidine, and muscle carnosine in both women and men. This confirms earlier studies that supplementing with beta-alanine increases muscle carnosine, therefore improving the capacity of the muscles to buffer during intense exercise. The research team emphasized their comparison on the differences between women and men, and recruited 26 men and women who were given a placebo or beta-alanine for 28 days. It was shown that beta-alanine really increased muscle carnosine but the differences between men and women were unclear.

Key Takeaways:

  • The University of Central Florida researchers have made a study and in the study they suggested that supplementing with beta-alanine can relieve fatigue.
  • The focus of the study that was published in the journal Nutrition Research was whether supplementing with beta-alanine has an effect on performance, muscle carnosine, and L-histidine.
  • Studies that were done earlier before this one has shown that supplementation with beta-alanine increases the intramuscular carnosine content and improves buffering capacity in intense exercises.

"The findings of the study suggested that supplementing with beta-alanine for 28 days can increase muscle carnosine and relieve fatigue in men and women, but did not reduce muscle L-histidine."

Read more: https://www.naturalnews.com/2019-03-19-beta-alanine-relieves-fatigue-increases-muscle-carnosine.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6246)


A healthy gut is a more efficient gut: Prebiotic fiber found tobreak down a high-fat diet better, reducing accumulation and inflammation
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Date: April 26, 2019 03:23 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A healthy gut is a more efficient gut: Prebiotic fiber found tobreak down a high-fat diet better, reducing accumulation and inflammation





Many of us are aware of fiber being an important nutrient, but what about prebiotic fibers? These are essential when it comes to cleansing the colon and regulating the metabolism, as well as digestion. A study showed that mice who were living on a high-fat diet without the presence of prebiotics showed to have troublesome symptoms such as a slower metabolic rate and less weight loss. This is in comparison to the mice who were given the replica of a high fat diet with prebiotic fibers present.

Key Takeaways:

  • The Cell Host & Microbe Journal published a piece lauding the addition of prebiotic fiber to an otherwise high fat diet.
  • Researchers found that such an addition proved to be a way to potentially avoid or lessen the effects of metabolic syndrome.
  • Researchers gave rodents on an otherwise high fat diet, inulin, a fermentable fiber supplement, to monitor the effects.

"People consistently overlook the importance of eating healthy foods, especially fibers which are known to cleanse the colon."

Read more: https://www.naturalnews.com/2019-03-07-prebiotic-fiber-breaks-down-a-high-fat-diet.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6199)


How to Manage Cholesterol Naturally
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Date: April 04, 2017 10:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to Manage Cholesterol Naturally





For starters, not all cholesterol is bad. Cholesterol is needed for body functions to occur. That being said there are many natural reasons cholesterol could be noted as dangerously high. Are you undergoing more stress than normal? Any recent surgery or infections? Any major dietary changes? All of these need to be considered before starting medication. An increase of fiber may do the trick as excess cholesterol is released in fecal matter. Anti-inflammatory foods such as food containing omega 3 and omega 6 also help as cholesterol rises when the body is inflamed. Finally, increase fruit and vegetable intake.

Read more: How to Manage Cholesterol Naturally

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4348)


What to eat: Broccoli vs. cauliflower - Bel Marra Health
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Date: February 13, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What to eat: Broccoli vs. cauliflower - Bel Marra Health





Broccoli and cauliflower are two vegetables that have a lot in common. They are both cruciferous vegetables and family members from the Brassica oleracea plant species. Both vegetables also originated from Europe’s Mediterranean region. Finally, they were likely both among the vegetables that you refused to eat as a kid unless they were covered with cheddar cheese sauce, of course.

Key Takeaways:

  • While both veggies are rich in vitamins A, C, and K, broccoli beats cauliflower, containing more of all three vitamins. In fact, one cup of broccoli contains 135 percent of your daily vitamin C intake
  • 11 percent of your vitamin A intake, and 116 percent of your vitamin K intake. In comParison, one cup of cauliflower accounts for 87 percent of your daily vitamin C requirements
  • The average man requires approximately 56 grams of protein daily, while the average woman requires around 46 grams. These numbers change with the level of activity you engage in

"The average man requires approximately 56 grams of protein daily, while the average woman requires around 46 grams."



Reference:

//www.belmarrahealth.com/eat-broccoli-vs-cauliflower/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3933)


How nutritious are plant-based milks?
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Date: December 03, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How nutritious are plant-based milks?





When deciding what type of milk to consume, it is best to read labels. While cow’s milk is fairly standard in the amount of nutrients it contains, plant-based milks can vary greatly depending on which company manufactures it. Unless there is a medical reason to do otherwise, it is recommended that all people consume cow’s milk. Soy, almond, coconut, and other nut milks can be lacking in their nutrients. Soy and nut milks contain a fair amount of protein, but none of the alternatives naturally contain calcium. It can be added, but these usually are not digested as well.

Key Takeaways:

  • Vegans and others may prefer to drink plant-based milks over milk that comes from animals, but a recent study in the Journal of Pediatric Gastroenterology and Nutrition confirmed that young children should drink cow’s milk.
  • An eight-ounce glass of cow’s milk naturally contains about eight grams of protein and almost a third of the recommended percent daily value of calcium.
  • Nutritionally, plant-based milks noted pale in comParison to cow's milk; none contain more than a gram of protein unless fortified.

"An eight-ounce glass of cow’s milk naturally contains about eight grams of protein and almost a third of the recommended percent daily value of calcium. Cow’s milk also naturally contains nutrients like potassium and vitamin B12, and is usually fortified with vitamins A and D."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.myajc.com/news/lifestyles/food-cooking/how-nutritious-are-plant-based-milks/ns83K/&ct=ga&cd=CAIyGjY3NzEzYzg1MjE0ZjUwYzU6Y29tOmVuOlVT&usg=AFQjCNFCC1HIvy4Tvv37PC3ave07tBwlUw

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3559)


Anti-Aging Powers of Broccoli Enzyme
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Date: November 25, 2016 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Anti-Aging Powers of Broccoli Enzyme





Recent research found that mice who were given NMN (nicotinamide mononucleotide) showed less signs of aging. The study, performed on mice, showed that subjects who received NMN had the same energy and metabolism levels as young mice. Though NMN is not readily available for human consumption, it can be found in foods like cucumbers, broccoli, edamame, avocados and cabbage.

Key Takeaways:

  • A great deal of human health depends on how well the body is able to manufacture and use energy.
  • Since human cells depend on the same process of energy production, there is hope that this will be translated into a method that can aid people in remaining healthier as they age.
  • The researchers made comParisons every three months until 17 months of age.

"The ability of cells to produce energy gradually declines with age."



Reference:

//www.worldhealth.net/news/broccoli-enzyme-anti-aging/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3508)


Benefits of Turbinado Sugar
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Date: February 08, 2014 04:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Turbinado Sugar

What is turbinado sugar

brown sugarTurbinado sugar is a sugar cane-based, minimally refined sugar. It is medium tan in color and has large crystals. It's frequently mistaken for traditional tan sugar because of its light tan color, however its made in an alternate way. Many kind of people believe by this to become more healthy compared to each whitened as well as suntan Sugars, because it is usually much less ready as well as processed.

Usage as well as Storage space

Formulations which demand turbinado Sugar tend to put it to use as an alternative with regard to conventional suntan Sugar. It has much more dampness compared to normal whitened or even suntan Sugars, which may be advantageous within such things as goodies or even cookies. In comParison, 1 should not really substitute desk Sugar along with turbinado within formulations which curently have a number of components decorating dampness, to prevent producing the actual determining product spongy. It's on / off once again imaginable to make use of turbinado Sugar as part of formulations such as these types of through decreasing the quantity of an additional moisturizing component or even making use of much less Sugar compared to is necesary, however it might take a few testing to find the last product to show away appropriately.

Turbinado Sugar is really a well-liked garnish with regard to cinnamon goodies as well as toasted bread, and it is frequently employed as part of graham cracker piecrusts. Cooking professionals could also put it to use upon creme caramel, because it touches as well as caramelizes nicely. Supplied on their behalf it's greater dampness content material, it may solidify in the event that set open up to numerous atmosphere. Producers recommend preserving this within an airtight pot inside a awesome, darkish location.

Color of sugar

The color may vary from an extremely gentle suntan to some more dark suntan. The actual color is actually molasses layer the actual deposits. Within processed whitened Sugar all the molasses may be eliminated.

Benefits of sugar

True turbinado Sugar is recognized as vegan because it doesn't touch any kind of pet items throughout it's produce. Processed whitened Sugar is generally handled along with bone fragments char, a good pet byproduct.

Uses of sugar

Turbinado Sugar, whenever accustomed to sweeten espresso as well as teas, provides one more taste. It may be utilized like a ornamental leading with regard to cooked products along with other sweets. It may be replaced with regard to whitened Sugar in several quality recipes, however it might alter the actual color associated with whitened meals.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3011)


Difference between Vitamin B-12 Cobalamine
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Date: January 06, 2014 01:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Difference between Vitamin B-12 Cobalamine

Vitamin B-12 occurs in many formations.

b12 foodsThe different formations of vitamin B-12, based on the functional group,is called cobalamine. The naturally occuring form in the human body is the dibencozide while the most common supplemented forms being the cyanocobalamine and methylcobalamine.

Differences between cyanocobalamine and methylcobalamine:

1. Cyanocobalamine has the presence cyanide ligand on the cobalamine and it is very stable and has a longer shelf live.Methylcobalamine, on the other hand, is an active cobalamine and has methyl ligand present in it.

2. Cyanocobalamine is converted into methylcobalamine in the body. The glutathione present in the human body removes the cyanide ligand and replaces it with methyl group. Cyanocobalamine is not recommended for persons who smoke as cyano group fails to detach in persons who intake tobacco. And hence the intake of cyanocobalamine can be fatal for smokers. It is also not recommended for those having liver failure since the glutathioneis formed in liver and hence if there is no glutathione the cyanide ligand cannot be detached and can pose threat to the body.4. At 1mcg dose cyanocobalamine is absorbed at 49.2% while methylcobalamine at 44.4%5. At 5 mcg dose cyanocobalamine is absorbed at 20.4% while methylcobalamine at 18.8%6. At 25 mcg cyanocobalamine is absorbed at 5.6% and methylcobalamine at 6.1% This indicates that cyanocobalamine is absorbed in the body better than methylcobalamine.The difference in the absorption can be attributed to the mass and the molecular structure of cyanocobalamine.Cyanocobalamine is cheaper than methylcobalamine and it has prolonged shelf life compared to other cobalamine forms. It appears as crystals synthesis and is red in color. Although the food rich in vitamin B-12 is enough for the body to meet the daily requirements, deficiency of this vitamin leads to disturbance in the sleep pattern, feeling of tingling in the body parts, numbness, etc

Reference:

  1. ComParison of vitamin B-12 forms by Michael Mooney/SuperNutrition October 2007

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2954)


What Is The Difference Between flaxseed oil and fish oil
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Date: January 01, 2014 07:03 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is The Difference Between flaxseed oil and fish oil

fish oilBefore you can compare flaxseed oil and fish oil

It is first important to understand the differences between the two oils. Extracted from the dried seeds of the plant rips linen, flax seed oil is clean and almost yellow. The oil is obtained by a cold method or by solvent extraction. Flaxseed oil contains acid lineolic, a particular form of omega-3 fatty acids. Fish Oil is extracted from the tissues of fatty fish containing EPA, Docohsahexanoic acid (DHA) and eicosanoids.

Benefits of compare flaxseed oil and fish oil

Some of the health benefits are reducing inflammation. For comParison, it is essential to analyze the benefits of both oils. Two omega-3 fatty acids, EPA and DHA in this oil and are a great help in creating hormone-like substance that reduces inflammation and blood pressure. They have also been shown to reduce triglycerides and the accumulation of plaque in the arteries.Omega-3 oils promote the secretion of serotonin. Serotonin is a chemical anti-depressant produced by the body and thus reduces or mitigates the effects of depression. Fish oil is often used in the treatment of patients with HIV / AIDS, and has proven to be helpful in lowering triglyceride levels in the body that build up after prolonged use of antiretroviral drugs. This is extremely useful because it can reduce the risk of a patient for coronary artery disease. In addition to providing relief from chronic inflammation, they is also useful for those suffering from joint pain, such as rheumatoid arthritis. The EPA has also found that fish oil helps protect the skin from photo damage. Photo damage is known to cause permanent skin wrinkles and skin damage. In addition, some studies have shown that they may prevent schizophrenia, with minimal side effects. Mothers who take fish oil during pregnancy often bear children with enhanced brain function as well as children with higher IQs. They are also less prone to cognitive problems. And the effects of postpartum depression seem to lessen with the regular intake of fish oil.The fish oil supplements have even more benefits, including lower risk of macular degeneration in the aging process. And studies have shown that with weight training significant reduced pain is present in the bodybuilders who regularly consumed fish oil. Other benefits are providing relief for digestive diseases..

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2945)


What are the health Benefits of Cod Liver Oil
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Date: July 11, 2012 08:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are the health Benefits of Cod Liver Oil

Cod Liver Oil Benefits

This is a nutrient rich oil derived from Cod fish liver and can be in the form of capsules or oil. The Cod liver oil has been used for many generations to treat various health conditions and to boost the human's immune system. Otherwise, it is one of the recommended nutritional supplements especially when it comes to enriching your system with:

- Vitamin A

- Vitamin D

- Omega-3 Fatty Acids

- DocoHexaenoic Acid (DHA),

- EicosaPentaenoic Acid (EPA)

All these nutrients are beneficial to the body in various ways and have proved to be great home remedies for conditions such as arthritis. So this is how all these nutrients will benefit the body.

Vitamin A

Vitamin A is an antioxidant which helps protect the body from the development of free radicals and in the long run reduce the formation of cancer cells in the body. Therefore, your system will be protected from cancer and other diseases owing to the presence of beta carotene and alpha carotene. On the other hand, since Vitamin A is an immune booster it assists in treating measles, respiratory infections, viral infections, improves your eyesight, Inflammation Reducer, and cardiovascular performance.

Vitamin D

One of the main benefits of Vitamin D is the fact that it helps the intestine absorb nutrients such as phosphorus and calcium which are vital for bone formation and strengthening. This is why Cod liver oil is an ideal home remedy for arthritis. It also prevents osteomalacia and weakening of muscles and rickets at the same time assist in regulation of blood pressure, reduces stress, tension, muscle aches and spasms and improves the general health of the skin.

EicosaPentaenoic Acid (EPA)

It it one of the main nutrients found in the Omega 3 fatty acids which normally assists in treating coronary heart disease, reduces formation of high triglycerides, controls high blood pressure and reduces inflammation. It also has a positive effect on depression, reduces formation of blood clots and improves the health of arteries. Actually, EPA is renowned for its positive effects on the health of the human heart.

DocoHexaenoic Acid (DHA)

DHA found in cod liver oil is a polyunsaturated fatty acid which is a main ingredient of the omega 3 fatty acids. Findings have it that DHA is an ideal component for controlling inflammatory disorders, arteriosclerosis, types of cancer, myocardial infection as well as thrombosis.

Omega 3 Fatty Acids

The omega 3 fatty acids are mostly beneficial owing to the presence of DHA and EPA. However, findings indicate that the the omega 3 fatty acids are crucial for the enhancement cognitive functions especially when it comes to the memory. It is also an ideal remedy for children with ADHD considering the fatty acids assist in enhancing behavioral functions.

In other words, the cod liver oil is one of the recommendable nutritional supplements owing to its overall benefits to the immune, circulatory, cognitive and cardiovascular systems. This means that one teaspoon of the cod liver oil could save you from many health situations in comParison to not having it at all. It is also advised that you take at least 1-2 tablespoons everyday especially if you need such nutrients to boost your immune system.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2665)


What Makes Neptune Krill Oil So Good For Your Health?
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Date: March 24, 2012 05:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Neptune Krill Oil So Good For Your Health?

Neptune Krill Oil

Neptune Krill Oil is a dietary supplement that is made from the a species of Krill, a small crustacean that is quite similar to a shrimp. Neptune krill oil is rich in omega-3 fatty acids. These krills are supposed to be the largest biomass in the world and are found in the Antartic and North Pacific Oceans. While these shrimp like creatures are small in size, there is an estimate of 500mn tons of krill in the ocean. Neptune Technology has the patent for krill oil extraction and hence the krill oil that is found as supplement comes from Neptune Technologies only. As Krill form important part of the food chain, especially in the Antartic region, there have been many krill farms being setup for harvesting of krill.

Health Benefits

Krill oil has many health benefits and is used as a dietary supplement as it contains important nutrients like omega-3 fatty acids similar to those found in fish oil, omega-3 fatty acids conjugated to phospholipids and astaxanthin. Lets us see what benefits of Neptune krill oil are:

Blood Sugar and Hyperlipidemia: Recent studies have shown the beneficial effects of krill oil in lowering blood sugar levels and totalcholesterol. Neptune Krill oil helps in lowering bad cholesterol (LDL), blood sugar, triglycerides and total cholesterol:HDL ratio. Hence it keeps your heart healthy and fit.

Premenstrual Syndrome: Neptune Krill oil is an effective and natural way to manage the symptoms of premenstrual syndrome. It not just gives relief from the physical symptoms such as bloating, breast tenderness and fatigue, but also helps in controlling the emotional symptoms (irritability, stress and depression) experienced by many women during their menses.

Inflammation relief: Studies have indicated that daily intake of krill oil helps in improving the joint health and thus helps in reducing inflammation and pain of arthritis.

Reduces risk of Cancer: Omega-3 fatty acids have anti-carcinogenic properties. Consumption of Neptune krill oil could reduce the risk of cancer. Studies have even shown that krill oil helps slowing down the growth of cancerous tumors.

Fish oil versus Krill oil: Which one is better?

Fish oil vs Krill oil is the most common debate that is becoming popular among health enthusiasts. This is because both Fish oil and Krill oil are the daily nutritious supplements that are loaded with potential health benefits. In essence, both of these oils share same characteristics in terms of their composition and their properties but still the comParisons between these two healthy oils continue. Let us discuss the pros and cons of fish oil vs krill oil and compare different parameters to decide it by ourselves, which one is better?

1. Krill oil contains higher amounts of anti-oxidants (astaxanthin) that are quite beneficial for health while many manufacturers add anti-oxidants from outside in fish oil.

2. Both the oils are rich source of omega 3 fatty acids, but fish oil contains high concentration of harmful metals that can cause unwanted side-effects if consumed.

3. Fish oil is made commercially from farm raised fish, which lacks useful nutrients, whereas krill oil is made from the pristine waters of Antarctica.

Krill oil is nature's rich source of important nutrients. Neptune krill oil is a vital supplement that has many health benefits.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2617)


What Are The Health Benefits Of L-Carnosine?
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Date: February 28, 2012 07:53 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Health Benefits Of L-Carnosine?

L-Carnosine

Among the numerous natural compounds in the body, L-Carnosine is also one such beneficial compound that is naturally contained in the human body. Numerous health benefits are offered by this compound, and it plays an integral role in maintaining the wellness of an individual. However, as people begin growing old, are frequently stressed or have undergone some sort of a trauma, then the levels of this compound in the body are decreased.

What is L-Carnosine?

This compound is basically a dipeptide that comprises of alanine and histidine, which are two different types of amino acids. The brain, heart, kidneys, muscles, skin and the stomach are the organs where L-Carnosinecan be naturally found. Due to its potent antioxidant traits, this dipeptide is regarded as an effective anti-aging agent.

What Are The Health Benefits Of L-Carnosine?

As mentioned, Carnosine is an integral dipeptide in the body and quite an array of benefits are offered by it.

Due to the intense antioxidant qualities of L-Carnosine, the free radical damaged caused within the body is minimized. Free radicals are not good for the cells present in the body since they damage and kill cells, and can also alter DNA too. Thus, Alzheimer's disease, heart disease, cancer and skin damage, are some of the health problems people can suffer from as a result of altered DNA, damaged and dead cells due to free radicals. In comParison to vitamin E, this compound can protect cell membranes from oxidation more effectively because it is water-soluble.

Other Carnosine Benefits

The compound also helps in healing wounds as well. The connective tissues in the body are effectively repaired thanks to the antioxidant qualities of Carnosine, and the skin is ideally healed. The compound also helps reducing the risk of wound infection too.

Cataracts and other eye conditions can also be relieved with the help of the health benefits offered by this compound. Even though this compound is naturally contained in the eye, however, as people get older, its amount lessens. Thus, primary and mature senile cataracts can be effectively cured with eye drops containing L-Carnosine.

Even the heart is kept healthy by this compound as well. The heart tissue muscle is strengthened by this compound and enzymes that enable the heart muscles to contract are also activated by it.

How to Increase the Level of L-Carnosine in the Body?

Those who want to increase the amount of this beneficial dipeptide in their body should eat a diet that essentially includes fish, meat and poultry. Dietary supplements can also supply the body with this compound. L-Carnosineis contained in certain multivitamin supplements, which contain various other amino acids, minerals, vitamins and other special nutrients. Thus, the overall positive effective of this compound in the body can be further enhanced by taking such supplements.

As long as the supplement being used contains nothing but natural ingredients, supplementing this compound in the body can help an individual avail many health benefits. L-Carnosine is, therefore, an important dipeptide and those who are growing old should consider supplementing it through diet or supplements.

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What Form Of Calcium Is The Best Calcium?
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Date: February 21, 2012 11:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Form Of Calcium Is The Best Calcium?

Best Calcium

Manypeople these days want to know which form of calcium is the best form of calcium. Calcium happens to be an essential nutrient for the body. However, since this nutrient serves a variety of purposes, therefore, it can be a bit tricky to determine which form is the best. There, in fact, might not be a single best form of calcium but probably quite a few, depending on what the calcium is needed for.

Calcium Complex (MCHA) Microcrystalline Hydroxyapatite

Everyone is aware that calcium is the building block of bones and for the treatment of a bone-related condition like osteoporosis; Calcium Complex (MCHA) Microcrystalline Hydroxyapatite is the best calcium. Supplements containing this form of calcium have, in fact, been proven to be effective at increasing bone density and reversing osteoporosis. Among the biological forms of calcium available, what makes MCHA one of the best forms of calcium for treating osteoporosis and increasing bone density is because it is excellent absorbed by the body. Calcium carbonate is often recommended by medical doctors because a very minimal amount of pills need to be taken.

Calcium Carbonate

For those who do not want to use a form of calcium derived from a biological, animal source and are, in fact, in search of the best calcium for the maintenance of bones, then Calcium Carbonate is perfect. This form of calcium is the second best in regards to absorption by the body. Calcium Carbonate is often recommended by medical doctors because a very minimal amount of pills need to be taken. Calcium Carbonate supplements can be found quite easily and they are mostly affordably priced.

Chelated Calcium

Supplementing calcium also becomes necessary for anyone who has recently undergone Bariatric surgery. While Calcium Carbonate can also be used in such a situation, however, the best calcium in this case would be Chelated Calcium. Chelated Calcium is a form of calcium that is used in combination with beneficial amino acids. In comParison to Calcium Carbonate, research has shown that Chelated Calcium is a far more biologically available form of calcium. However, the dosages of this calcium that need to be taken are generally quite large. Above all, Chelated Calcium supplements can be quite costly too.

Calcium Citrate

Calcium Citrate is an ideal alternative to Chelated Calcium, in fact, it is another form of Chelated Calcium, but the supplements that contain this form of calcium are usually more inexpensive. Not only this, those who choose to use this form of calcium will also get to take lower dosages. Calcium Citrate is a form of calcium that is acid based and is quite capable at supplementing the body with calcium since it is quite effectively absorbed. Since no additional stomach acid is required for the absorption of this form of calcium, therefore, Calcium Citrate at just about any time.

There are many other forms of calcium that are quite ideal for the body as well and can prove to be beneficial as well. This is the reason that those in search of the best calcium will come across numerous choices and some of the best ones were mentioned here.

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What Is The Difference Between DGL Licorice and Regular Licorice?
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Date: February 13, 2012 07:35 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is The Difference Between DGL Licorice and Regular Licorice?

Manypeople these days have heard of the name “Licorice” because of the various chewy rope-like flavored confectionaries or candies that are widely available these days and taste amazingly sweet. However, most of these people have never paid attention to what these candies are made of. The fact is that these candies contain the extract from Licorice roots. The Licorice roots are yielded from the Licorice or the Glycyrrhiza glabra plant. The extract from these roots has been used from quite a long time, both as a food ingredient and as an herbal remedy.

However, the Licorice root also has a derivative form known as deglycyrrhizinated or DGL Licorice. Both of these products offer numerous benefits and when taken under medical supervision they can effectively help in treating a variety of medical ailments.

Licorice plants originate from the Middle East, where harvesters peel the root out of the plant, dry them, cut them and eventually the Licorice roots arrive in other countries. Glycyrrhetic acid, cumestan derivatives, hydroxycoumarins, isoflavonoids, triterpene saponins, etc. are some of the active constituents contained in regular Licorice roots. One problem with using Licorice roots was that it was generally recommended that people use the extract from the root only under medical supervision. This was mostly because of the Glycyrrhetic acid contained in the root.

Thus, while DGL Licorice is indeed derived from Licorice root, however, glycyrrhetic acid is removed during the preparation of DGL. Therefore, this form of Licorice can be consumed much more safely without any worries. Furthermore, ulcers the esophagus, in the mouth and the stomach lining in the small intestine are more effectively treated with this derivative form of Licorice. DGL Licorice is presently widely available as chewable tablets, mouthwashes and even teas; therefore, people have a few choices as to how they want to take the derivative extract that comes from the root of the Licorice herb.

DGL is actually an effective treatment for digestive problems like heartburn and GERD or gastroesophageal reflux disease, ulcer, etc. What makes this derivative extract so beneficial is that the protective factors of the digestive system are accelerated and/or stimulated by its mechanism as a result of which the internal lining of the intestines in the stomach are protected against the formation of ulcer. Unlike typical antacids and anti-inflammatory drugs that basically neutralize or suppress gastric acid, the DGL extract functions quite differently.

Apart from helping treat the mentioned digestive problems, even minor skin conditions such as carbuncles, eczema, minor cuts and wounds can also be effectively treated by applying ointments that contain DGL. Apart from being better than the regular extract obtained from the Licorice root, the DGL derivative is also far more effective anti-ulcer compound in comParison to the typical medications that are available these days. It is usually advised that DGL should be taken at least twenty minutes before meals. And usually 2 to 4, 400 mg tablets are the standard dose of DGL that can be taken for chronic cases of ulcer. Therefore, those who are considering using Licorice root extract should instead go for DGL Licorice.

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Your Diet May Be What's Causing Your Acne
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Date: September 19, 2011 06:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Your Diet May Be What's Causing Your Acne

Although dieticians and physicians maintain that diet does not cause acne, this is not strictly true. Even dermatologists argue the point, but while it is generally agreed that eating fatty foods or excessive quantities of chocolate will not in itself lead to acne, there are certain valid arguments that diet has a role to play. Recent research has shed new light on dietary factors that can help to promote acne symptoms, if not being the sole cause of them.

Before discussing that, it is important to understand why acne gives rise to the symptoms that it does: lesions in the form of whiteheads and blackheads, pustules and cysts. While not necessary to discuss the biochemical details, the part that your diet has to play will not be understood without considering the effect of hormones on acne.

The reason that teenagers in particular appear to be more prone to acne is that an increased production of hormones has an effect on the condition that causes the symptoms of acne. Fundamentally, acne is characterized by the infection and inflammation of a mass of oil and dead skin cells within the pores of the skin, particularly on the face, neck, chest buttocks and back. If we discuss each of these elements first, and how they are created, then the relationship between diet and acne will become clear.

At a certain time in their lives, people experience a spurt of growth and develop sexually. This is initiated by the secretion of hormones, particularly of male sex hormones collectively known as androgens, and by various hormonal 'Growth Factors'. This stage of human development is known as puberty, although there is also an increase in androgen secretion by the adrenal glands just before menstruation and during pregnancy and menopause. Androgens such as testosterone are reserved not only for the male of the species!

An effect of androgens is to increase the rate of secretion of sebum from the sebaceous glands in the skin. The reason for this is unknown, though it has been hypothesized that its purpose is to waterproof the additional hair that is grown on the body at this time. Another suggested reason is as an olfactory warning to others to deter from sexual activity, in teenagers until their sexual development is complete, and in pre-menstrual, pregnant and menopausal women for obvious reasons. There is no substantial proof for any of these hypotheses, though the latter appears to make more sense than the former.

Irrespective of this, androgens also interfere with desquamation, and the dead skin cells within the pores tend to fall off irregularly and in clumps. This mix of dead skin cells and excess sebum clogs up the pores of the sebaceous follicles. Once this plug becomes infected with bacteria, the immune system is activated, inflammation occurs, and leukocyte action leads to pus formation. That is what is known as acne.

In order to determine how diet and acne are connected, it would be necessary to determine what components of our diet can either stimulate sebum production, or stimulate androgen secretion. If no such link could be found, then it would be fair to descry any connection between acne and the food you eat. However, there is a connection, and it is a positive one.

In addition to their main function, insulin and a hormone known as IGF-1 (Insulin-like Growth Factor 1 that helps promote growth in children) promote the secretion of testosterone, a male hormone or androgen. Knowing, as we now do, that androgens promote the secretion of sebum, then anything that increases the levels of insulin or IGF-1 within the body will also lead to sebum production and hence to acne. What that infers is that any foodstuffs that increase the insulin levels in the blood can also lead to acne.

This inference is supported in many ways. For example, it has been found that while drinking milk promotes a greater risk of acne, eating yoghurt does not. Why is this? It is known that milk can increase insulin levels because of its high sugar content. The effect of bacterial activity to produce yoghurt reduces the amount of sugars in the milk it is made from because the bacteria live on the lactose. The same argument applies to cheese, which promotes lower insulin levels than milk, if not as low as yoghurt.

This being the case, then a diet low in sugars and carbohydrates should reduce the incidence of acne generally. Recent research has indicated that a diet high in refined carbohydrates and sugar increases both IGF-1 and insulin levels in the blood. This then creates a surge in male hormones which in turn leads to excessive sebum secretion and intermittent shedding of skin cells and so on to the growth of bacteria and acne. It is a logical progression, supported both by theory and by observation.

So how should a person with a propensity for acne change their diet? Switch to fruits, vegetables and grains. Non-fatty meats are also acceptable, and .lots of fish and other seafood. Studies have concluded that diets rich in seafood lead to very low acne rates. The Japanese and coastal Chinese suffer very little acne in comParison with those taking a Western diet, particularly an American diet.

One of the reasons for this is that omega-3 fatty acids help to reduce both inflammation and sebum production. The same is true of green tea that contains antioxidants that reduce the blood levels of dihydotetosterone and hence of sebum secretion by the sebaceous glands. We could go on, and list supplement after supplement that contain antioxidants and other substances that can reduce the production of sebum and hence of the symptoms of acne.

Vegetable oils, on the other hand, with their high omega-6 fatty acid content, can drive up sebum production and the activity of the immune system and the inflammatory response. There are few doubts left that, while acne is not specifically caused by what you eat, diet can contribute to it and that acne and its severity can be eased by eating a diet low in carbohydrates and other sugar-promoting foods.

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How Does Progesterone Cream Help Ease Hot Flash Symptoms?
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Date: June 21, 2011 11:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Progesterone Cream Help Ease Hot Flash Symptoms?

Progesterone And Hot Flashes

Progesterone cream is an all natural remedy for hormonal imbalances in the female body. It has grown in popularity in the past few years largely owing to very strong anecdotal evidence. Its use in the management of hot flashes has produced very encouraging results, and thus has become a mainstay of alternative treatment for vasomotor symptoms of menopause and premenstrual syndrome.

Plants contain fats and oils that can be modified in the laboratory to partially synthesize progesterone. The active ingredient of most progesterone creams in the market is diosgenin, which is a plant sapogenin that occurs naturally in wild yams. Diosgenin has long been noted for its steroidal activity inside the human body, but it has been successfully converted to progesterone only recently.

Reverses Estrogen Dominance

The concept of estrogen dominance is central to the appearance of hot flashes. A group of medical professionals believe that vasomotor symptoms are brought on by fluctuations in hormonal levels, among other factors. While both groups of female sex hormones experience changes, progesterone is thought to approach near depletion in comParison with estrogen. Hence, the latter dominates.

Progesterone creams work on the principle of reversing estrogen dominance. They are formulated to facilitate optimum absorption into the body. While their active ingredients, such as diosgenin, have been noted to produce estrogen-like activities when unmodified, progesterone creams function exactly in the same manner as endogenous secretions of progesterone.

Increases Progesterone Levels

Hot flashes are often linked to changes in body temperature. It has long been postulated that hormonal imbalances have an effect on the hypothalamus, which regulates body temperature. It is believed that depleting levels of progesterone lead to a series of chemical reactions that confuse the biological thermostat, resulting in vasodilation of blood vessels close to body surfaces.

Progesterone creams effectively relieve hot flashes because the active ingredients are capable of penetrating the part of the skin that leads to the blood vessels. There is very good evidence that topical applications of progesterone are readily absorbed. Since fats and oils from plants have high absorption rates, progesterone creams are certain to increase progesterone levels in no time.

Normalizes Hormonal Changes

There has not been any contraindication associated with the regular use of progesterone creams as most of them are formulated in concentrations suitable for use at any time of the day. In fact, it can be applied to the skin even in the absence of hot flashes to prevent any vasomotor symptoms. A growing of body of literature has noted its efficacy in managing hormone-related imbalances.

More importantly, progesterone creams have shown great promise in stabilizing hormone levels in the long run, making it an ideal remedy for women suffering from premenstrual syndrome. Also, it is very likely to help women who are surgically menopausal as they experience very intense episodes of hot flashes that last until the natural age of menopause.

Grab some progesterone today and feel the relief it can bring!

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Using SAMe for Depression
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Date: June 04, 2011 10:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Using SAMe for Depression

SAMe, or S-adenosyl-L-methionine, has been promoted for the treatment of depression and various physical conditions. It is believed to help improve the feeling of well-being and mood, and its use in treating depression is likely connected with that.NOW - SAM-E 2X 200MG   60 TABS 1 Several studies have been carried out, administering SAMe both orally and parenterally with promising results. Some that use it believe it more effective than the more common antidepressants, and unlike most of these it has very few side effects and a very quick onset of action: around 2 weeks in comParison to a month for most others.

A typical study of the many carried out involved 30 subjects taking regular antidepressants but still suffering depression. They were given 0.8 grams SAMe for 2 weeks and then 1.6 grams for 4 weeks. Improvement was obtained in 50% cases and complete remission of symptoms in a total of 43% of the subjects. In another test on 28 subjects, the improvement equaled that of prescription antidepressant drugs.

These significant findings render this over the counter supplement (in the USA) worth taking for anybody that has either no effective help from their regular treatment, or would prefer to try a natural biochemical than a synthetic drug for their condition. You are recommended to refer to your doctor, however, if you intend changing your treatment.

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Potassium: Cardiovascular Health, Muscle Function, Cellular Activity, And Blood pH
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Date: May 11, 2011 12:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Potassium: Cardiovascular Health, Muscle Function, Cellular Activity, And Blood pH

Potassium is a dietary mineral required in relatively large quantities in comParison with other minerals found in the human diet. It is the most abundant positively charged ion, or cation, in the cytosol, the liquid cytoplasmic matrix found inside all cells of the human body. It has a special relationship with sodium, the major cation outside animal cells. Together they facilitate cellular reformations and intercellular activities, greatly influencing the development of muscles, the brain, and the heart.

Electrolytes are solutions of bases or acids that help maintain a healthy pH inside the body. Potassium is an electrolyte absolutely necessary for the upkeep of cells. They enable organic compounds to move charges, which is central to neuronal activities, muscle contraction, and endocrine functions. The presence of potassium is also required to activate the catalytic functions of several enzymes. Some of these enzymes are indispensable in the metabolism of carbohydrates.

Powers Cellular Activities

A cellular phenomenon described as membrane potential affects several types of cells throughout the human body, such as neurons, muscle cells, and endocrine cells. Potassium is involved in this phenomenon, powering countless molecular devices found in the cell membrane much like a battery. It also participates in transmitting signals between cellular organelles, creating an electric current that flows between different parts of the cell.

Intercellular communication that induces the release of neurotransmitters, hormones, and other related organic compounds throughout the body rely on healthy levels of potassium. For example, it allows the beta cells of the pancreas to respond to levels of carbohydrates that get in and out of the systemic circulation, releasing insulin when needed. It fuels a chain of cellular events that lead to many bodily functions.

Promotes Muscle Function

It is not a coincidence that unhealthy levels of potassium lead to bouts of muscle cramps. While involuntary contractions of the skeletal muscles are often associated to older populations, they may afflict people of all ages at any time of the day. More often than not, the underlying cause is malnutrition, especially deficiency in dietary minerals like potassium.

Contractions produced by skeletal muscles are a classic example of physiological functions that necessitate the presence of potassium. When electrical impulses of cell membranes rise and fall at a very fast rate, it results in a cellular event called action potential, igniting a chain of events that lead to muscle contraction. This is the reason why potassium is important in the maintenance of healthy muscles.

Maintains Cardiovascular Health

Potassium is particularly good for the heart. The cardiac muscle is engaged in continuous coordinated contractions that propel blood out of the atria and ventricles to the rest of the cardiovascular system. A condition called hypokalemia, in which the level of potassium in the blood is low, has been linked to abnormal heart rhythms, high blood pressure, and congestive heart failure. Not surprisingly, potassium supplements are used as a therapeutic remedy in the treatment of these diseases.

pH Balance

Potassium has a pH of 14. Taking potassium daily can help you regulate your pH so you can maintain a pH of 7 throughout the day. By maintaining a pH of 7, you can improve your health and reduce the instance of illness.

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Is Elderberry Good for Colds and Flu?
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Date: April 14, 2011 03:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Elderberry Good for Colds and Flu?

Elderberry and your Health.

Elderberry is a plant species best known for its medicinal properties believed to effectively treat colds and flu. It is native to Europe and North America, but also has a significant presence in the Middle East. It is cultivated for its flowers and fruits, which are utilized for both culinary and medicinal uses. The flowers are often made into a popular juice, which is the flavor of many local soft drinks. The fruits are consumed raw, and only consumed when fully ripe.

Sambucus nigra is the plant species generally referred to as elderberry although the term elder encompasses the entire genus Sambucus, which comprises up to 30 species. Most species of elderberry thrive well in damp regions where the soil is moderately wet and the area quite shaded, and sambucus nigra is no exception. This species is noted for their dark purplish berries and creamy white flowers, both of which are edible. It is usually categorized as a shrub, but it can grow up to 10 feet on average, looking much like a small tree.

Elderberry has been ascribed with herbal properties since the ancient times, with an emphasis on the amelioration of flu symptoms. All its parts are historically noted for their specific uses. The bark is utilized as an herbal treatment for cardiovascular, digestive, and renal conditions. The leaves are used to disinfect wounds. The berries are for inflammation, allergies, and skin disorders. And the flowers are usually used to relieve sore throat, colds, and influenza. Today elderberry extracts found in health products are obtained from various parts of the plants.

Stimulates Faster Immune Responses

The organic compounds naturally occurring in elderberry appear to speed up the immune responses implicated in viral infections, notably the common colds and influenza B. In Europe, elderberry has enjoyed overwhelming popularity in comParison with other herbal remedies for colds. Indeed it contains unique flavonoids believed to be responsible for stimulating the immune system. Its anti-inflammatory, antiviral, and antibacterial properties are all attributed to the same organic compounds.

Reduces the Severity of Cold Symptoms

Researchers are enthusiastic about the outcomes of preliminary studies. Earlier studies in Europe recorded noticeable improvements in best known symptoms of the common cold, such as runny nose, nasal congestion, headaches, and sinusitis. Furthermore, it shortened the duration of cold infections. And since its preparations have not been associated with any adverse effect, it can be administered to people of all ages. Succeeding studies conducted in North America yielded very promising results, cutting the severity of symptoms and defeating infections fast.

Effectively Treats Influenza Infections

There have been several studies looking into the efficacy of elderberry preparations, and all of them pointed to a compound called Sambucol. It was first observed to be a viable treatment for Influenza B infections, but more recent studies came to a conclusion that it also effectively treats influenza A. In all studies, Sambucol helped over 80 percent of patients suffering from flu in less than 3 days.

Keep Elderberry on hand in case of emergencies

It is good to keep elderberry on hand for when a cold rears its butt. Starting elderberry at first signs of a cold can greatly increase its effectiveness.

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How Does Boswellia Fight Inflammation?
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Date: April 13, 2011 03:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Boswellia Fight Inflammation?

Boswellia refers to the species of trees where the aromatic gum resin frankincense is obtained from. In herbal medicine, the term Boswellia often means Indian frankincense, which is noted for its potent anti-inflammatory properties. It has a centuries-old association with Ayurvedic medicine, and herbal preparations containing its extracts are formulated for arthritis. It now comes in supplements marketed as a viable treatment for inflammation-induced illnesses, such as arthritis, colitis, and asthma.

Asthma

Indian frankincense, also known as dhoop in India, is entirely derived from Boswellia serrata, and the common frankincense from a completely different species. The earliest known study looking into its purported benefit as an anti-inflammatory medication was in 1998, and it investigated its effects on asthma. In a span of 6 weeks, the boswellia group took 300 mg of the preparation three times a day and 70 percent experienced a significant improvement in symptoms and a noticeable decrease in incidence of asthma attacks in comParison with the control group.

Arthritis

In Ayurvedic medicine, boswellia has been utilized for hundreds of years with an emphasis on its use in the amelioration of joint pains. It is generally considered safe, explaining its prevalence in the treatment of arthritis and related disorders. Boswellia was the subject of several studies devoted to better management of osteoarthritis, and these studies published results that attracted more research. Today it is also touted to be useful for rheumatoid arthritis, which is inflammatory in nature.

Colitis

Recent studies yielded outcomes in favor of its anti-inflammatory claims. In 2007 one study pointed to its medicinal potential in the treatment of colitis, concluding that patients with chronic inflammation of the colon went into remission after regular intake of boswellia. In a similar study, individuals diagnosed with inflammatory bowel disease reported to have benefited from 6 weeks of supplementation while those who sought conventional treatments responded to their medications in a much longer time.

5-lipoxygenase

Boswellia remains under scrutiny. Anecdotal evidence has been very positive largely owing to the fact that it hasn’t been linked to any adverse effect at all. But how does it work? There are many chemical reactions which boswellia may be directly involved in. It has been observed that it reduces the synthesis of pro-inflammatory leukotrienes. These mediators of inflammation are produced in the presence of an enzyme called 5-lipoxygenase, which is thought to be counteracted by the high terpene content of boswellia.

Leukocytes

Triterpenes in boswellic acid, the active ingredient unique to boswellia, are also believed to interfere with the adhesive interactions between leukocytes and endothelial cells present in the gastrointestinal tract. Leukocyte elastase is a serine protease, a special kind of enzyme, released by leukocytes or neutrophils during inflammation. It is postulated that boswellia down-regulates leukocytes and leukocyte elastase in addition to inhibiting the expression of endothelial cells adhesion molecules. Down-regulation of leukocytes will help reduce inflammation and improve health.

If you are fighting systemic or joint inflammation, give boswellia a try and feel the difference!

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What is Oligonol Good for and How Does It Boost My Health?
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Date: March 22, 2011 03:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Oligonol Good for and How Does It Boost My Health?

Oligonol is the first ever nutritional supplement to contain low molecule polyphenolic oligomers. These polyphenols are derived from the plant Litchi chinensis, also known as lychee in the vernacular. The name oliginol is a portmanteau for oligomer polyphenol, which is widely touted to display bioavailability far superior to high molecular weight polyphenols present in most antioxidant supplements and the plants that they are extracted from. It boasts the most recent innovation of producing higher biological activity by using the low molecule technology developed by the Faculty of Pharmaceutical Sciences of Nagasaki University in collaboration with Amino Up Chemical Co. Ltd.

Polyphenols have long been known to create health effects that are antioxidant in nature. These organic compounds have been tied to quenching reactive oxygen species, or ROS, a natural by-product of oxygen metabolism. ROS like free radicals are in fact deployed by cells in response to potential threats such as invasive pathogens. Given the high reactivity of free radicals, each cell releases endogenous antioxidants to scavenge ROS. However, the body’s antioxidant defense becomes compromised with continued exposure to stress.

At the cellular level, an imbalance between ROS and antioxidants creates a chain reaction termed oxidative stress, which damages cellular organelles and even DNA. This is when antioxidant supplements come to the rescue. Plant-based polyphenols such as those found in teas is widely believed to neutralize free radicals. Those found in lychee are of special note in that they are particularly helpful against oxidative stress. The proprietary low molecule technology of Amino Up Chemical Co. Ltd. processes these already potent polyphenols into more effective monomers and short-chain oligomers.

Protects Cardiovascular Health

Since oligonol was made available nearly two years ago, there have been a number of studies looking into its medicinal potential. A few of the earliest researches were double-blind, placebo-controlled clinical trials that investigated its effects on the cardiovascular system. It has been observed that oligonol appears to lower platelet reactivity, contributing to dilation of peripheral vessels. By so doing, it effectively promotes blood flow, which results in an increase in body temperature.

Counteracts Physical Fatigue

Recovery to fatigue induced by physical exertion is one of the benefits of oligonol that have been well investigated. In one single blind, placebo controlled study involving 47 participants, intake of oligonol lowered post exercise fatigue. The oligonol group of amateur athletes between 18 and 22 of age took two 100-mg oligonol capsules in two 26-day periods with a 9-day wash-out period and saw a noticeable improvement in fatigue recovery in comParison with the control group.

Reduces Visceral Fat

Oligonol continues to excite researchers from around the world with the publication of the study on its effects on visceral fat. There are cell-signaling protein molecules released by adipose tissues that are considered deleterious to human health, and thus called bad factor. Adiposity has been tied to higher mortality, with people having larger waists especially susceptible to many known diseases. Supplementation of oligonol has seen a sharp decrease in abdominal circumference and overall subcutaneous fat.

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Is AHCC Good for the Immune System? How So?
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Date: March 02, 2011 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is AHCC Good for the Immune System? How So?

AHCC And Immune Health

Active Hexose Correlated Compound, or AHCC, is one of the most commonly used food supplements in Japan largely owing to its effective immune-boosting properties when successfully absorbed by the human body. The earliest important study concerning its activities in the immune system was published in the early 1990’s at Tokyo University, triggering a sudden rise in popularity among consumers in Japan, where it is sold over the counter.

Activates White Blood Cells

It has been observed in the past few years that AHCC boosts the immune system in many different ways in that it participates not only in the innate immune system but also in the adaptive immune system. Of special note is the significant increase in certain types of white blood cells, including natural killer cells, or NK, and macrophages. NK cells are in the employ of the innate immune system and responsible for the disposal of cells infected by viruses. They are often the first line of defense against common viruses such as herpes, containing the damage that viral infection spreads while waiting for specified mechanisms of the adaptive immune system. This is when macrophages come into play along with a cohort of lymphocytes. Their relatively bigger size allows them to effectively engulf pathogenic cells and the enzymes they contain break these pathogens down.

Removes Antigens and Toxins

AHCC also influences the production of antigen presenting cells, or APC. In a double-blind, placebo controlled study involving healthy individuals there was a significant increase in the quantities of APC, notably dendritic cells, in comParison with the baseline, and proteins released by lymphocytes called interferon. Both APC and interferon facilitate the detection of antigens and toxins created by invasive foreign bodies and alert the rest of the immune system of their presence. Dendritic cells are considered the most important group of all APCs in that they present a wide range of antigen presentation by way of phagocytosis or endocytosis, two different ways of catching antigens. By so doing, they make it easier for white blood cells to eliminate antigens and other toxic substances.

Defends against Cancer Cells

Cancer patients are the group of individuals that have benefited the most from AHCC. Early studies yielded data that are now being used to enhance the quality of life of those diagnosed with cancer. Indeed boosting the immune system has proven to play a part in the battle against cancer, and AHCC stimulates the immune system to manufacture a class of white blood cells that actively defend the body against cancer cells by causing tumor cells to die and on the same principle delay the proliferation of malignant cells.

There have been extensive clinical trials well underway in many countries, including China, South Korea, Thailand, Spain, and the US. These studies aim to that rigorously test its efficacy. In fact, AHCC belongs to the group of nutritional products tied to alternative medicine that has been supported by an abundance of data in connection with its safety and recommended dosages.

If you are battling disease, give AHCC a try.

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Horsetail
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Date: August 31, 2009 01:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Horsetail

Horsetail has been used for healing in both Chinese and Asian cultures. During times of famine, the Romans ate horsetail shoots, while Native Americans used horsetail as a diuretic for kidney problems, cancer, and dropsy to increase blood circulation. The Hopi tribe in New Mexico mixed horsetail and cornmeal as a mush and in their bread. One of the oldest plants on the earth, horsetail is approximately two hundred million years old. It used to be a giant fernlike plant. However, there are now around twenty species of the original plant living today. These species are small in comParison to the original plant and are usually considered to be a nuisance. The species Equisetum arvense is a small perennial fern plant that is most common in North America.

The horsetail plant is a descendent of huge tree-like plants that thrived 400 million years ago during the Paleozoic era. The plant is a non-flowering weed that can be found throughout parts of Europe, Asia, the Middle East, and North America. This plant returns each year with hollow stems and shoots that resemble asparagus. As the plant dries, silica crystals, which form in the stems and branches, give the plant the scratching effect that made it historically useful for polishing metal.

Horsetail is believed to aid the immune system and the nervous system because of its silica content. The nerves contain almost the same amount of silica as does the albumin in the blood. The pancreas is especially rich in silica. Silica is found combined with fluorine in the enamel of the teeth. Additionally, hair needs silica to grow, and it is needed as a protection for the skin and cell walls. This herb helps in treating urinary tract problems. It contains silicic acid, which is responsible for helping with circulation of the blood. This herb is also credited with helping coagulate the blood and decreasing blood flow. An externally-applied decoction has the ability to stop bleeding of wounds and help with healing. Horsetail can also be used as a mouthwash for mouth infections. Often found in calcium combinations, horsetail is helpful in building the skeletal system and improving bone structure. The silica that is found in horsetail also helps in healing bones, keeping the arteries clean, and facilitating the absorption of calcium in the body.

This herb is known for its antibiotic properties and its contribution to the overall healing process. Horsetail is also thought to help with bleeding, urinary and prostate disorders, bed-wetting, skin problems, and lung disease. Horsetail also possesses a weak diuretic effect, which is most notably due to the equisetonin and the flavone glycosides.

In short, the entire horsetail herb is used to provide alterative, antilithic, antineoplastic, astringent, diuretic, emmenagogue, galactogogue, lithotriptic, nephritic, nutritive, and vulnerary properties. The primary nutrients found in this herb are flavonoids, iodine, iron, manganese, PABA, pantothenic acid, silicon, sodium, and vitamin E. Primarily, this herb is extremely beneficial in treating arthritis, poor circulation, diabetes, glandular problems, weak hair, kidney stones, weak nails, nervousness, osteoporosis, parasites, rheumatism, and urinary problems.

Additionally, this herb is very helpful in dealing with edema, eyestrain, gas, gout, heart problems, hemorrhage, incontinence, liver disorders, membrane irritations, neuralgia, palsy, skin disorders, tumors, and water retention. For more information on the many beneficial effects provided by horsetail, please feel free to contact a representative from your local health food store.

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Bee Pollen
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Date: May 20, 2009 12:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bee Pollen

Bee pollen is made up of the fine powder that is found in the male seed of a flower blossom. Bees transport this powder and mix it with nectar to create their own form of nourishment. The pollen grains are collected and eaten by the bees, but they are also used to pollinate the flowers. Since the beginning of time, bee pollen and honey have been recognized for their astounding healing benefits. Egyptian records going back thousands of years have references to honey and the potential for healing that it holds. Marathon runners of ancient Greece recognized the value that bee pollen held to increase their strength and endurance. Bee pollen was also revered by European nations and Asian countries for its medicinal value.

Bee pollen is considered to be a complete food due to the fact that it contains every chemical substance that is needed to maintain life. This makes it a great supplement to help build the immune system and provide the body with energy. Recent scientific research has found that bee pollen contains properties which are beneficial to healing, revitalizing, and protecting against radiation therapy. Bee pollen is also a rich source of protein and carbohydrates. This nutrient can not only be used as a food supplement, but also to correct body chemistry and normalize weight.

Scientists at the Institute of Bee Culture in Buressur-Yvette near Paris, in addition to other researchers throughout Europe, have studied the effects of honeybee pollen consumption on human beings. The study concluded that there are exceptional antibiotic properties in bee pollen. It was also found that bee pollen is helpful in treating conditions like chronic fatigue, hay fever, allergies, bronchitis, sinusitis, asthma, colds, balancing the endocrine system, and menopausal symptoms. Additionally, bee pollen can be helpful in treating other conditions such as prostate problems including prostates, infertility, indigestion, constipation, colitis, anemia, high blood pressure, premature aging, depression, and hair loss.

Bee pollen has also been shown to improve one’s concentration and mental function. A study found that a group of students’ mental performance improved drastically when supplementing with bee pollen. This nutrient also reduces cholesterol and triglyceride levels. It does this by preventing plaque buildup in the arteries. This supplement is often used by athletes to increase strength, endurance, and speed.

The pollen of bees is used to provide both alterative and nutritive properties. The primary nutrients found in bee pollen are twenty-one amino acids, enzymes, essential fatty acids, and variable vitamins and minerals. These vitamins and minerals depend on the region that the bee pollen is harvested in. Primarily, bee pollen is extremely beneficial in dealing with aging, allergies, hay fever, loss of appetite, lack of endurance, exhaustion, fatigue, a weak immune system, infection, multiple sclerosis, and pregnancy problems.

Additionally, bee pollen can be extremely helpful in treating asthma, high blood pressure, cancer, depression, hypoglycemia, indigestion, liver diseases, prostate disorders, and radiation. Bee pollen is available in capsules, tablets, and bulk powder forms for easy consumption. Always look for name brands to ensure quality and purity of the bee pollen product you purchase. For more information on the many beneficial effects provided by bee pollen, please contact a representative from your local health food store.

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Herbs
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Date: October 09, 2008 01:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbs


Herbs have been used for a long time as foods to heal disease in our human society. It can be estimated that herbs have been used by humans for at least 15,000 years, with animals using the herbs as medicine for much longer. They, fortunately, had the instinct to search and find the herb they need when it is needed, while our animals of today are limited by fences. Many veterinarians claim that horses will go out and look for a plant that will be helpful to get them to get rid of a parasite when they have it. This plant is called Wormwood. A lot of the first herb uses were actually learned from observing and ill animal and watching it go out and get a plant. Man then followed and ate the plant himself.

The Indians in South American discovered that the Pau d’Arco tree possesses a lot of medicinal ability in the inner back by observing that the inner bark repelled the insects that flooded other trees in the rain forest. The Indians also found a bush that is found in a certain canyon increased their eyesight, so they named it Eyebright. Similarly, the Arizona Apache and Pima Indians found that if they took a twig of the Chaparral bush and heated it and placed it in or next to a tooth hoe, the pain and infection were relieved.

Because of the above, it can be inferred that man has been using herbs for an extremely long time. This is important, especially when taking it to comParison just how short-term the use of chemicals has been. There is no doubt to anyone that chemical use over a long period of time causes a negative effect on the human body. It seems extremely odd that the scientific community prefers their scientific laboratory experiments with chemicals over 4,000 to 5,000 years of herb use. It seems as if someone would see the inadequacy of trying to find a medicine in laboratories by working with animals over a period of months versus the use of herbs by humans in their natural habitat for thousands of years.

Chemicals are not food for the human body as they have all sorts of negative effects including unwanted immune responses which cause inflammation. They do not provide any nutritional affects. Herbs, on the other hand, are foods that fuel the human body, nourishing it and also cleansing it so that it may be energized. Additionally, these herbs have a lot of unknown positive effects. This seems so simple that some wonder how anyone in a professional status could see the truths in prescribing a drug for their spouse or client. A lot of times it is suggested that patients ask their doctors if they would prescribe the same drug or surgery for their wife or children. We need to become aware of the responsibility we have to our bodies. Many herbs have Glyconutrients and polysaccharides that can feed the immune system. These Glyconutrients or polysaccharides are simple sugars that provide raw materials for the body to build its self better and stronger. Every cell in the body is wrapped with instructions. When the immune system come in contact with each cell, it determines whether its friend or foe. Herbs can help the body build its self better.

Those people who ask if they will become dependant on an herb are thinking of the herbs as a drug instead of food. Although we are dependant on food, it is better to eat food that has been proven to help our body, rather than one which will poison it. Herbs are foods that have proven elements involved which will provide a positive effect on our body. Each specific herb can provide a specific need to our body.

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Wormwood, Black Walnut, Triphala
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Date: June 17, 2008 08:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Wormwood, Black Walnut, Triphala

Wormwood Intestinal Detox With Triphala and Artemisi

  • Clears and detoxifies the GI tract
  • Promotes a healthy immune system
  • Aids the development of natural, healthy gastrointestinal flora

Wormwood Intestinal Detox™ is a unique combination of purifiers for clearing the intestines of potentially toxic waste matter and supporting a healthy environment where beneficial flora can thrive. This formula, developed by renowned acupuncturist and clinical herbalist Michael Tierra, combines potent, traditional herbal ingredients such as sweet wormwood (Artemisia annua), black walnut hulls and the classic internal cleanser and tonic Triphala, to help clear the intestines and support a healthy gastrointestinal environment. Wormwood intestinal Detox combines historically known wormwood and black walnut together for a powerful worm Parisite fighting combination along with its other synergistic ingredients can help the body rid itself of toxic material and move foward with a healthier happier life.

2 tablets contain:

Proprietary Blend: 1.6 g

Sweet Wormwood Aerial Parts Extract (5% artemisinin), Black Walnut Hull Extract (4:1), Butternut Bark Extract (4:1), Chebulic Myrobalan Fruit, Grapefruit Seed Extract (Citricidex™) (49% polyphenolic compounds), Belleric Myrobalan Fruit, Fennel Seed, Quassia Wood Extract (4:1), Amla Fruit Extract (40% tannins), Marshmallow Root Extract (4:1), Epazote Whole Plant Extract (15:1), and Ginger Rhizome Extract (4:1).

Suggested Use: 1 to 2 tablets twice daily between meals.



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Coral Calcium
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Date: May 16, 2008 02:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coral Calcium

The health benefits of coral calcium were discovered in 1979, when a British journalist representing the Guinness Book of records traveled to Okinawa to talk to Shigechiyo Izumi, who at 115 years old was at the time the world’s oldest documented living human being. Not only was the journalist impressed and surprised at how healthy such an old man was, but he also found that good health to be shared by the majority of Okinawa’s aged residents.

After his report was filed on his return to England, a team of researchers were sent to the island to make further investigations in the phenomenon. They found that the key to their longevity was the water they were drinking. The water of Okinawa appeared unique, and coral calcium was discovered.

It was not only the calcium, of course, that made such as difference but the whole mineral balance of the water. Okinawa is formed of coral reefs built up over millennia, and rainwater filters down through the coral collecting minerals and other nutrients on its way. This water is both alkaline, with a pH of 8.6, and closely resembles the natural mineral composition, not only of the human skeleton but also of body fluids such as blood plasma and amniotic fluid. It seemed the ideal stuff to bottle, and there are now over 4 million users of coral calcium in Japan alone.

The commercial use of Sango coral, as it is called, is controlled by the Japanese government, and living coral is left untouched: only the dead coral sand lying on the ocean bed is used. The sand is collected and cleaned, and then pulverized and the calcium and all the rest of the minerals it contains are easily absorbed by the body.

It is this ease of absorption that renders coral calcium so useful. Most minerals find it difficult to pass from the intestine to the bloodstream, but this is not a problem for the minerals in Sango coral. Because they do not come from inorganic mined minerals, but from natural organic sources, they are present in a very bio-available form and are readily absorbed into the bloodstream. It not only contains the common minerals calcium, magnesium, potassium, sodium, and so on, but also many trace elements that are essential for life. Not only that, however, but they also contain antioxidants to help prevent the oxidative stress caused by free radicals, and also at a pH that allows the minerals to become naturally ionic very readily.

It is this ionic form of each mineral that permits it to be so readily available to your system. This was a major discovery at the time, since the form that inorganic minerals generally come in had been a problem prior to this to the extent that only 10% was absorbed by the body. In comParison, 95% of the coral calcium and other minerals are able to be easily absorbed since they are in an ionized form – an even higher absorbency than colloidal minerals allow.

Why are minerals so important and how can they possible lead to such an effect on the elderly of Okinawa? In fact minerals are very important components of human metabolism and biochemistry. Most believe vitamins to be significantly more important to human health than minerals, but this is not the case. Many vitamins are useless without the synergistic effect of minerals, and the reverse is also the same.

For example, calcium needs vitamin D to be present before it can be used by the body to strengthen bone structure. There are many other such interactions involving vitamins and minerals, and without chelation (the rendering of large organic molecules to a soluble form by combining them with metal ions) many of the essential biochemical processes of life would be impossible. Coral calcium contains all the minerals found in your body, and in very similar proportions, so that you are able to use it to maintain that all important synergism and not throw the mineral balance of your body out of balance. This is very easy to do if you take individual mineral supplements.

However, there is still more to come from this remarkable substance. It is also rich in antioxidants that spell death for free radicals. Free radicals can’t really die, because they are not living entities but molecules that have a free electron, and free electrons like to pair up with other electrons. Free radicals are therefore very aggressive when near any body cell from which they can rob an electron, and that, unfortunately, destroys the cell.

Not only that but they also oxidize molecules from which they take the electron, and if that is a low density lipoprotein, or LDL, that happens to be carrying some cholesterol to one of your arteries that needs a bit of repair work, then it will cause the LDL to deposit the cholesterol immediately and form plaques that constrict and narrow your arteries. That is called atherosclerosis and it can kill you or give you a stroke. Cholesterol is essential for good health, but once the free radicals get to work you are better without it.

However, Sango coral contains substances that prevent the free radicals from oxidizing other substances, and in so doing destroy them. That’s what antioxidants do. They prevent free radicals from oxidizing other molecules and creating all sorts of havoc with your health. Excessive amounts of free radicals have been associated with over 80 different conditions, and one of the benefits of coral calcium is that it is one of the most powerful antioxidants known.

It is not only the mineral content and antioxidant properties of coral calcium that are of benefit to the human body, but also its pH. The various fluids of your body are maintained at a specific pH, which is a measurement of the acidity or alkalinity of a fluid. This should be slightly alkaline without being caustic. If your body fluids are too acidic it becomes difficult for you to absorb minerals and vitamins, and it is essential for you maintain a balance of from around 6.4 to 7.0 Any lower than that and you will find it difficult to sleep and you will feel listless with no energy.

You can measure the pH of your body by testing your urine with pH strips available at any pharmacy. Coral calcium can be used to maintain a good pH level that allows your body to absorb the nutrients it needs, and keep you feeling not only well, but young and sprightly just like Shigechiyo Izumi did at 115 years old.

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Ubiquinol Reduced CoQ10
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Date: April 07, 2008 01:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol Reduced CoQ10

Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.

Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.

In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.

CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.

While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.

In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.

A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.

As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.

The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.

Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. ComParisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.

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Omega-3 Relieves Depression in Some Individuals
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Date: November 02, 2007 03:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega-3 Relieves Depression in Some Individuals

Omega-3 oils contain fatty acids that are known as essential fatty acids because they cannot be manufactured in your body but have to be taken in your diet. They provide many benefits to your body, and are also believed to relieve depression in some individuals. First, however, an overview of the more conventional benefits of omega-3 oils.

Obtainable in your diet from oily fish such as mackerel, herring, salmon and the like, omega-3 fatty acids play an important part in your normal growth and development, and are also crucial to normal brain function. They can reduce inflammation and protect you from heart disease and some cancers. Studies have shown the fatty acids to be particularly concentrated in the brain and to be important for cognitive processes and memory.

The effects of omega 3 fish oils on the brain are well documented, and they are known to be effective treatments in some cases of bipolar and schizophrenia. It is believed that they could also be used as a treatment in other disorders such as attention deficit disorder and dyslexia, but there is as yet no evidence that this is the case.

Omega-3 fatty acids reduce the so-called ‘bad’ low density lipoprotein (LDL) cholesterol levels and increase the high density lipoproteins (HDL) that take the cholesterol back to the liver for destruction. The end result is a reduction in the cholesterol content of the blood that can be deposited on the artery walls and promote atherosclerosis. Diets high in omega-3 fatty acids appear to lower blood pressure in those suffering from hypertension, and so reduce their chances of heart attacks and strokes.

Omega 3 oils are also natural inflammatories, and help prevent conditions involving inflammation such as arthritis, asthma and menstrual cramps. They appear to help the immune system to fight these conditions and reduce the inflammation and its causes.

They are also important in the formation of prostaglandins that are responsible for the regulation of important functions such as blood pressure, blood clotting and immune response. They are hormone-like substances and also control the synthesis in the body of other hormones. If the balance of fatty acids in the diet is not right, then the subsequent imbalance in prostaglandin and hormone production can lead to disease.

It is in its effect on depression and mood, however, that has surprised many in the medical, profession. Ethyl-eicosapentaenoate, known as ethyl EPA, is a constituent of omega-3 fish oil and many studies have demonstrated that this substance helps cases of depression and related disorders. However, are people justified in turning to ethyl EPA to help them be cured of this condition?

In one study involving 20 people, six out of ten people given the supplement displayed significantly reduced symptoms of depression after four weeks. The effects were noticed as early as two weeks and many of the depression symptoms, such as worthlessness and insomnia, had improved after three weeks. This conformed with the results of many other studies that have been carried out world wide. In Scotland, a number of patients were studied who had failed to respond to traditional antidepressant drugs. Of the seventy patients involved in the trial, all of the patients who were treated with EPA displayed significant improvements in all the symptoms of their depression after four weeks whereas those with the placebo showed no improvement.

Of the two main components of omega-3 fish oil, EPA and docosahexaenoic acid (DHA), only the EPA has this property, and the EPA works best alone when the DHA has been extracted. Studies and tests have indicated that the DHA appears to be important for the brain’s structure, but the EPA for its function, hence the reason for the ineffectiveness of the former in relieving depression which is a function of the brain rather connected to its structure. In fact, depressed people have been found to be deficient in EPA in comParison to those not suffering from the condition. The original idea for this originated with the late Dr. Horribin who was pioneer in researching the effects of lipids on the biochemistry of the brain as far back as the 1970s. Since then the world-wide research has confirmed his theory. However, the reason why this theory works in practice is not yet understood. It has been established that a diet rich in trans fats can unfavorably affect the hormones in the brain that stabilize mood, possibly due to the fats slowing down the system of messaging within the brain. This kind of effect can cause depression.

This is likely due to the slowing down of the messages passing between the synapses. Brain cells communicate by means of chemicals that cross the synapses, or small gaps between the individual cells. They are not directly connected like normal electrical circuits. It has been theorized that the EPA speeds up the passage of these messages between neurotransmitters and neuroreceptors. Other theories have also been promoted, such as that the EPA has properties of its own that cure depression by another route altogether.

A possible clue could be in the findings of one study on a man aged 21 years old whose brain was scanned before and after EPA treatment. The result showed in increase in the mass of brain cells after the treatment. This was contrary to the belief that brain cells could neither be generated nor grown once a person reaches maturity.

An individual suffering depression who would like to treat themselves with EPA would have to buy a lot of oily fish since high doses are needed for this level of therapy. However, it is found in high concentrations in a few supplements available on the market, and when choosing you must use the highest grade of EPA you can get, with as low a DHA content as you can find.

There is little doubt now; however, that the EPA content of omega-3 relieves depression in some individuals, although more work is needed to prove without doubt that it is effective with all forms of depression.



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Coconut Oil May Help Promote Healthy Thyroid and Digestive Function
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Date: November 01, 2007 09:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coconut Oil May Help Promote Healthy Thyroid and Digestive Function

Coconut is extracted from coconuts, the coconut palm often being called the tree of life and for good reason. However, its benefits were lost to America for many years due to the politics of the vegetable oil industry claiming that all saturated fats are bad. This is not based on scientific or medical fact, and coconut oil was recently rediscovered in the USA, and the health benefits enjoyed by the rest of the world are once again available to Americans.

Coconut palms grow in most tropical climates such as Southern California and Florida, the Philippines and the Caribbean. Refined coconuts oils are mass produced and much of the beneficial nutrients are lost by the refining process. Virgin coconut oil is by far the better form, though is a slower process. It is generally obtained by shredding and dry milling the meat, and then cold pressing to produce the milk. The milk is fermented for a day or so and the separated oil collected.

Such oils are analyzed to contain over 50% lauric acid and high levels of phenolic antioxidants. Much higher than from refined oils. It is said to be the healthiest oil on earth. So why did the American authorities legislate against its use? It is because of the bad press received by saturated fats and oils.

You can have saturated, monounsaturated and polyunsaturated fats. The majority of the fats and oils in our diet are composed of long chain fats and oils. The chain length refers to the length of the hydrocarbon chain, whether saturated or unsaturated. It is long chain saturated acids that are bad for your cardiovascular system, and that should be avoided. However, there are also short chain and medium chain fatty acids that are more easily metabolized by the body. Coconut oil consists predominantly of medium chain fatty acids that help to protect against heart disease and cholesterol rather than promote it.

The highest levels of medium chain fatty acids are found in coconut oils and palm kernel oils, and these are far more nutritious than the saturated long chain fatty acids found in animal fats and just about all vegetable fats. The main MCFA in coconut oil is lauric acid.

Lauric acid is generally regarded as being responsible for the vast majority of the health benefits of coconut oil. The only other source of this fatty acid other than coconut oil is in human breast milk. After absorption, lauric acid is metabolized into monolaurin that is the monoglyceride used by the human body to destroy viruses and microbes, and attack the fat coated viruses that cause such diseases as HIV. It destroys flu viruses, a number of dangerous bacteria and protozoa such as giardia lamblia.

However, let’s have a look at some of the lesser known effects of coconut oil, such as its effects on the thyroid. Anything that blocks the efficient operation of the thyroid and secretion of the thyroid hormones can lead to excess estrogen in the body that can contribute to excessive blood cholesterol. There is a body of evidence that polyunsaturated fats and oils, such as soy, can have this effect is many people. When coconut oil is used instead, the medium chain fatty acids do not have the same effect, and those that are affected frequently find that their thyroid problem is cured and their blood cholesterol reduces.

This is not to infer that all hypothyroidism can be cured through the use of coconut oil, only those cases caused by consumption of excessive amounts of polyunsaturated fats. Although this is refuted by some medical practitioners that are against the use of supplements in general, it has been supported by medical evidence.

Coconut oil is also good for the digestion, and helps the cure of many digestive problems including Crohn’s Disease. It helps to build lipoproteins, fats and bile in the liver, the latter being essential for digestion. It helps to create a much healthier digestive tract that makes for generally better digestion and more efficient use of the foods you eat. Absorption of the nutrients is maximized and you feel altogether better in yourself when you take a small amount of coconut oil daily.

You can have sugar cravings for a number of reasons, and taking coconut oil can reduce these quickly and effectively, irrespective of their cause. The medium chain fatty acid breaks down and is rapidly metabolized to glucose thus providing a source of the energy your craving is telling you that you lack. It is very useful in reducing sugar cravings without you having to eat excess sugar that can create yeast problems.

If you replace the fats you are currently eating with coconut oil, it will not only act as an appetite suppressant but can also help you to lose weight. The fatty acids in coconut are absorbed immediately and converted to energy thus reducing your immediate need for food and hence your appetite. If you eat the saturated fat in coconut oil rather than the polyunsaturated fats in vegetable oils, then you can lose weight.

Many of the benefits of coconut oil are due to the speed with which the lauric acid is absorbed and metabolized in comParison to the long chain polyunsaturated fats. It is the chain length of the hydrocarbon tail that is important here rather than the number of double bonds in that chain that determines the degree of unsaturation.

Make sure that it is virgin coconut that you use since that is the most nutritious form. Do not be misled by labels claiming the contents to be extra virgin oil, since that is a term borrowed from the olive oil industry, and there is no such thing as extra virgin in relation to coconut oil. Never use refined coconut oil since that will just as bad for you as other saturated oils. Not even ‘Extra Virgin Refined Coconut Oil’ in the mistaken belief that such a label must indicate that the oil is extra good. It does not – it simply indicates that the supplier is a charlatan deliberately trying to mislead you into paying a premium price for a useless product.

Coconut oil may promote a healthy thyroid and digestive function, and all the medical tests indicate that it does. People that use it regularly swear by it and if you have a problem that virgin coconut oil might help, then one thing is sure: it will certainly do you no harm, and all indications are that it will do you a lot of good.



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Ubiquinol
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Date: October 24, 2007 11:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

Benefits

Ubiquinol has powerful antioxidant actions in target cells *

 

Although ubiquinone (oxidized coenzyme Q10) and ubiquinol (reduced coenzyme Q10) are kept at a constant ratio within the body, the majority of the total coenzyme Q10 pool is made up of ubiquinol.  In fact, when ubiquinone is taken orally, much of it appears to be rapidly converted into ubiquinol. 1,4 Ubiquinol functions as a potent antioxidant in humans, including in low-density lipoproteins (LDLs) where it protects them from oxidative damage.1,4,5 The coenzyme Q10 molecule can be found in all membranes throughout cells.6 It appears to works in conjunction with both vitamin E and vitamin C to provide antioxidant actions throughout the body.7

 

Coenzyme Q10 supports mitochondria to enhance cellular energy production*

 

Coenzyme Q10, with its widespread distribution throughout the body, plays a crucial role in mitochondrial physiology as a critical member of the electron transport chain. This transport chain, which is part of cellular respiration, leads to the formation of adenosine triphosphate (ATP), our body’s primary energy source.  Levels of this key nutrient may decline as a healthy person ages.7,8  Animal studies have found that supplementation can restore normal levels in certain tissues 6, and human studies suggest that supplementing with this enzyme may have increased benefits when a person has depleted levels. 7

 

Coenzyme Q10 supports healthy heart functioning*

 

Concentrations of coenzyme Q10 are understandably high in the heart as these muscle cells require high levels of energy to constantly function optimally. A number of studies (both animal and human) strongly suggest that coenzyme Q10 supplementation is supportive for healthy heart functioning and for maintaining cardiovascular system health.7,9

 

Ubiquinol has been studied for safety and bioavailability in humans*

 

A recently published single-blind placebo-controlled study in healthy subjects found no safety concerns in people who took Kaneka’s QH ubiquinol supplement orally at doses of up to 300 milligrams daily for up to four weeks.4 Single oral doses of either 150 milligrams or 300 milligrams were given to fifteen healthy men and women, and standard laboratory testing (including hematology, blood chemistry, and urinalysis) as well as physical examination and electrocariography (EKG) results showed no clinically significant changes when tested two days after supplementation as compared to before the taking the supplement. In addition to the single dose study, 80 healthy volunteers were given either placebo, 90, 150 or 300 milligrams of ubiquinol each day for four weeks, and again no clinically significant differences were seen in any of the testing parameters after two and four weeks of supplementation, nor were there differences two weeks after discontinuation of the supplement.  By monitoring levels in the blood, the authors found that ubiquinol was well absorbed.4

 

Studies in several animals also reveal no concern of toxicity in doses of ubiquinol up to 200 milligrams per kilogram of body weight for up to thirteen weeks.4 When compared to humans, this dose level is enormously higher than the recommended doses.  Supplementation with ubiquinol appeared to be safe at even higher levels (up to 600 milligrams per kilogram body weight) in a study using a different animal. In vitro assays additionally found no safety concerns for the use of ubiquinol, as it was found to be non-mutagenic and did not cause damage to chromosomes in cells.

 

Safety

Suggested Adult Use: Take one softgel daily with food, or as directed by a nutritionally informed physician.

 

Scientific References

1.    Mohr, D., V.W. Bowry, and R. Stocker, Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta, 1992. 1126(3): p. 247-54.

 

2.    Weber, C., et al., Effect of dietary coenzyme Q10 as an antioxidant in human plasma. Mol Aspects Med, 1994. 15 Suppl: p. s97-102.

 

3.    Okamoto, T., et al., Human serum ubiquinol-10 levels and relationship to serum lipids. Int J Vitam Nutr Res, 1989. 59(3): p. 288-92.

 

4.    Hosoe, K., et al., Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol, 2007. 47(1): p. 19-28.

 

5.    Stocker, R., V.W. Bowry, and B. Frei, Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proc Natl Acad Sci U S A, 1991. 88(5): p. 1646-50.

 

6.    Crane, F.L., Biochemical functions of Coenzyme Q10. Journal of the American College of Nutrition, 2001. 20(6): p. 591-598.

 

7.    Jones, K., et al., Coenzyme Q-10 and cardiovascular health. Alternative therapies, 2004. 10(1): p. 22-31.

 

8.    Schulz, C., et al., ComParison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10). Int J Food Sci Nutr, 2006. 57(7-8): p. 546-55.

 

9.    Coenzyme Q10. Monograph. Altern Med Rev, 2007. 12(2): p. 159-68.

 



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Omnivore Vs Vegan Who Is Right?
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Date: October 21, 2007 07:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omnivore Vs Vegan Who Is Right?

The omnivore vs vegan argument as to who is right and who is wrong can be argued from a number of different platforms. There is the ethical issue of whether we should eat other animal life, and also the argument as which is ‘better for you’, based on arguments such as vitamin B12 is not available from a vegan diet. There is even the ‘lifestyle’ argument: does our lifestyle define our diet?

However, strictly, the only argument for or against either diet should only be made upon human biochemistry. Do both meet the needs of our biochemistry, or does one or the other lack something essential in our biochemical pathways? Obviously omnivores will lack nothing except by choice, since all foods are available for their consumption. If vegans do lack a specific chemical need, then is that available as a supplement in a form that can be effectively used in the chemistry of our bodies.

The one argument accepted by both sides is that it is essential for all animals to consume living things in order to stay alive themselves. These living thinks need not be alive at the time of consumption, but it is necessary that they eat the flesh of plant or animal life that at one time was alive and contained DNA. What that infers is that it is only vegetables that can survive on non-living tissue and this appears to be borne out in practice. No living animal known can live on inorganic matter only, but most plants can and do. Not all though, the Venus fly trap being an example.

It is easy to extend the moral problem of eating living tissue to living vegetable tissue that also contains DNA, and the argument must lie between animal and the derivatives of animals, and non-animal tissue. It has not yet been found that any organism has yet crossed the animal-vegetable divide, so the division is a valid one. That might seem obvious, but it is necessary to establish that for the argument between vegan and omnivore diets to be valid.

The consumption of protein derived from meat is not a prerequisite for size and muscle bulk, since the largest dinosaurs in the world were all herbivores, the largest being a member of the sauropod family at more than 175 tons, eclipsing the largest meat eater, the gigantosaurus at 8 tons. Thus, meat does not mean bulk. However, what has been proved is that the fastest creatures are carnivores. Hence if you want to be a top class sprinter, eat meat!

Carnivores, with their lean muscle mass and highly efficient quick use of available energy, have very short digestive tracts which are not good for digesting vegetable matter, but make best use of animal proteins and expel unnecessary mass from the body quicker. The argument in favor of the vegans is that the human digestive tract is not that of a carnivore.

In herbivores, the food takes longer to digest, and hence it remains in the digestive system longer. This means a longer alimentary canal, longer than humans have. Herbivores also move slowly, and a good example is the comParison of speed between the omnivorous chimpanzees and other small monkeys and the herbivorous gorillas and orangutans. On the one hand you have lean fast moving machines, while on the other you have large bellies and slow moving larger animals. Check out cows and sheep and compare their body fat with ours. Nor are we like herbivores.

So what are humans? Omnivores! Our teeth and intestines are those of omnivores, the teeth designed for ripping and tearing meat, and stripping leaves from trees, but also for grinding grains, and our intestines are something between the long and the short. People are able to eat and live on every type of food imaginable from brains to intestines to leaves to roots to ants and grubs.

The argument is therefore futile to consider historically. Let’s then study the advantages and disadvantages of each type of diet. Human beings are capable of life through consuming either animals or plants, or both. The argument seems, therefore, to be one of morality rather than biochemistry. However, is that really so? The vegan refusal to eat dairy products should not be taken as extremism, since the human being is the only animal species to drink milk of another species, or to use it to make other products. It is a practice born long after cattle were husbanded by humans for food. The problem with eating animal products lies not in the meat itself, but in the fat. Animal fat is saturated, which means that the fat molecule has no active double bonds in the chemical structure that can be used to break the fat down.

Animal fat also contains cholesterol, yet we cannot survive without cholesterol. It is the human band aid, used by the body to patch up damage to the cardiovascular system. Only, sometimes, too much is laid down and the arteries get blocked. However, many vegetable products have more saturated fats and cholesterol than many animal products, so a balance is called for. The unsaturated fats and oils for humans are said to be derived from seeds, such as flax seed and fish, especially oily fish. These are the Omega-3 oils. Although they can be obtained from some seeds and nuts, it has been proved that the best come from oily fish, such as wild salmon, mackerel and sardines.

The B vitamins are essential for life. The best sources are animal sources, though you get them from some vegetable sources such as brewers years (who eats lost of that?) and others, but animal sources are the best.

Also, there is no evidence to suggest that vegans live longer than omnivores. In fact all of the evidence indicates that a middle road is the best. For human beings the healthiest diet includes both meat and vegetable tissue. The best solution to good health is neither vegan nor carnivore. Nor is it traditional vegetarian, since it is the dairy products that cause many of our dietary products.

Studies of the biochemical pathways have demonstrated that all chemicals need to sustain healthy human growth and life are not available from a classic vegan diet. Some animal protein and B vitamins are essential that cannot be obtained form a normal vegan diet. It is possible, however, to maintain life by means of supplements.

However, for the healthiest form of human life, our biochemistry, history and physiology indicate that there is a balance somewhere between the extremes of both views that is right for us, and that either diet can be sustained with appropriate supplementation based upon what is missing from one diet or the other.

So, omnivore vs vegan. Who is right: both are right if they also supplement any nutritional deficiencies in their diet with vitamins and minerals that may be lacking from one diet or the other.



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Pumpkin Seed Oil is good for your health
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Date: October 14, 2007 05:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pumpkin Seed Oil is good for your health

Pumpkin seed oil, as the name suggests, is obtained from pumpkin seeds, which can also be eaten roasted in the same way that people eat sunflower seeds. When roasted, they are coated in a sauce such as Worcester sauce and then heated in low oven for a long period of time. The secret of roasting them to maintain their nutritional value is to keep the temperature low and the cooking time high.

The seeds are regarded as a ‘superfood’ that is rich in vitamins A and E, the essential fatty acids known as Omega 3 and Omega 6, zinc, iron, magnesium and potassium. The seed is known as a pepita in North and South America.

The oil is reddish green and many people find it delicious. It is best when used raw, and can be drunk in the form of smoothies or shakes, or used as a salad dressing. Some also enjoy drinking it raw, and using it as a spread instead of butter or margarine. The benefits it provides to the human body are a healthy brain function, increased energy and it has a special use in maintaining a healthy prostate gland.

The vitamin E content is high, especially gamma-tocopherol, and it has a high antioxidant effect with consequent anti-inflammatory properties. Its effect on arthritis, and inflammatory disease, has been investigated and the inclusion of pumpkin seeds in the diet has been found to reduce the inflammatory symptoms of the condition with a consequent reduction in pain. In fact, in a comParison test with indomethacin, a common arthritis treatment, pumpkin seeds compared very well and in fact had a more positive effect on the damage to the fats in the joint linings than did indomethacin, which tends to increase the concentration of lipid peroxides rather than reduce them.

Its effect on the prostate gland is partially due to its high zinc content that is present in a higher concentration in the prostate than in any other gland in the body, and also to its effect on the hormones that cause the gland to grow and swell to the extent that it constricts or completely blocks the urethra, the tube connecting the bladder to the outside of the body. This is caused by an enzyme that converts testosterone to dihydrotestosterone (DHT). DHT causes the over-proliferation of the prostate cells.

The reason for the effect of pumpkin seed oil on DHT is still under discussion, but some believe that it is connected with the zinc content and others with the high level of delta-7-sterine in the seed. The sterine appears to neutralize the effect of the DHt on the growth of prostate cells.

In addition to prostate enlargement, Osteoporosis is another problem associated with aging in men. It has been estimated that men over 50 have a 12.5% chance of suffering a fracture due to brittle bones, and it is though that this is connected with a deficiency of zinc. In fact a clear correlation has been established between osteoporosis in older men and low levels of zinc and the diet and in the blood. Pumpkins seeds, as already mentioned, are rich in zinc, and the benefits of their use as a supplement to avoid an enlarged prostate is reinforced by their effect in protecting against osteoporosis.

Pumpkin seeds contain a high concentration of the antioxidants lutein and zeaxanthin. These are specifically useful in protecting the cardiovascular system and prevent atherosclerosis. They also contain plant sterols known as phytosterols that are believed to help reduce the blood concentration of cholesterol. This types of sterols are the basis of the ‘cholesterol busting’ drinks that are sold in supermarkets. They also help to strengthen the immune system and are believe to help reduce the risk of contracting some types of cancer.

Pumpkin seed oil is a rich source of alpha-linolenic acid, an important unsaturated fatty acid that some studies have indicated can be used to prevent metastaes (the spread of the disease) development in patients with breast cancer. The most prized type of oil is that from Syrian oil, from the province of Steiermark in Austria. Such pumpkins are also grown in parts of North America, and the best oil is said to come from the first pressing, the so-called ‘virgin’ oil. If used in cooking, the temperature must be kept low, since many of the nutrients are destroyed much over 100 Celsius.

A little known use for pumpkin seed oil is in eradicating intestinal parasites. Many people are embarrassed at requesting professional help for worms, and pumpkin seeds are the ideal home remedy. The act almost immediately, and two or three hours after taking them, or the oil, then you should take a laxative. You should the parasites being removed with the bowel motions.

The worms are not actually killed, but are paralyzed, and cannot prevent themselves being removed with the bowel movement. If a laxative is not taken, however, they will recover and there will be no effect. As with any remedy for a health condition, therefore, it is necessary to understand how the seeds or oil work to help to remove the horrible parasites from your body. They are very common, and any self-help or natural remedy that actually works will undoubtedly be very popular, but if it is not understood that these creatures must be expelled from your body while paralyzed, then pumpkin seeds or oil will not work.

Those that failed to understand the process would then complain that the treatment does not work. In fact, it does work, and if the worms are expelled when they are unable to remain in your intestines then they will be removed. You must “read the instructions on the bottle” for the contents to work.

Pumpkin seed oil is a very potent mixture of chemicals that can cure or control a large number of conditions, and it is essential that you understand why you are using them. They can be used as a supplement to your diet, though it is easy to wonder why you should take this antioxidant rather than another.

Find out what pumpkin seed oil can do for you, and if it applies to you then use it. There are stronger antioxidants, and better foods to take in an attempt to protect from certain conditions. However, there are certain circumstances when pumpkin seeds will do the job better than most other supplements, and if you can fit them into your regular diet then they will not only do you ‘no harm’, as they say, but will do you a great deal of good. Look for organic pumpkin seeds or pumpkin seed oil at your local health food store.



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Complete Liver Cleanse
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Date: April 19, 2007 04:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Complete Liver Cleanse

Complete Liver Cleanse

Technical Data Sheet

 

DESCRIPTION:

The liver performs over 500 functions, including metabolizing carbohydrates and proteins, synthesizing and storing vitamins, and regulating hormones – naming just a few. To do this job, the liver is also required to be exposed to potentially harmful toxins and chemicals, every day.

One way to support the liver is through periodic supplementation with the proper balance of herbal ingredients, phytosterols, and fiber. Complete Liver Cleanse is a convenient, multi-ingredient formula that supports overall liver health and detoxification.

Complete Liver Cleanse:

Includes ingredients for various aspects of liver and gallbladder support:

-Herbal ingredients that support liver and gallbladder health

-Detoxifying ingredients that keep bound toxins from being reabsorbed

-Phytosterols to block cholesterol absorption in the intestines

-Fiber that moves cholesterol and toxins out of the body

-Oat beta-glucan fiber with up to 4 times higher viscosity than other beta-glucan

Fibers

-Simple, two week liver cleanse program

FORMULA:

Each 3 capsules contain:

Calcium (as calcium D-glucarate) 13 mg

Proprietary PuraFiber Blend: 1 mg

Viscofiber Oat B-Gucan Concentrate, phytosterols

(beta sitosterol, campesterol, stigmasterol, brassicasterol,

and other plant sterols), and glucomannan

Milk Thistle (Silybum marianum) Fruit Phytosome 220 mg

One part Milk Thistle Extract, standardized to contain 80%

Silymarin bound to two parts phosphatidylcholine (soy) using

a patented process

Burdock (Arctium lappa) Root Extract 4:1 100 mg

Calcium D-Glucarate 100 mg

Boldo (Peumus boldus) Leaf Extract 2:1 75 mg

Turmeric (Curcuma longa) Rhizome Extract 50 mg

Standardized to contain 90% curcuminoids

Dandelion (Taraxacum offinale) Root Extract 4:1 50 mg

Artichoke (Cynara scolymus) Leaf Extract 30 mg

Standardized to contain 13-18% caffeylquinic

Acids calculated as chlorogenic acid

Contains no: sugar, salt, yeast, wheat, dairy products, artificial coloring, artificial flavoring, ingredients of animal origin, or preservatives. This product contains natural ingredients; color variations are normal.

Other ingredients: See label for most current information

Viscofiber is a registered trademark of Cebena Bioproducts, Inc. The use and composition of the Viscofiber proprietary formula is protected by patients and patent applications filed in the U.S., Canada and internationally.

This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by U.S. patent 4,845,123.

HOW DOES IT WORK?

The Liver

Every day, the liver must process an almost unbelievable amount of blood – at a rate of three pints every minute. All the while, the liver performs over 500 physiologic functions, including protein and glucose synthesis, carbohydrate metabolism, vitamin and mineral storage, synthesis of clotting factors, urea formation, metabolism of medications, and the production of bile. The liver also assists in hormonal regulation, blood glucose control, and other regulatory functions.

Harmful substances that have been neutralized by the liver are carried to the intestines and kidneys for excretion. They are transported by bile, a greenish, watery solution that is synthesized, and continuously being excreted, by the liver. Stored in the gallbladder, a small sac cupped in the under surface of the liver, bile is also required for the digestion of dietary fats. However, in the case of toxins, bile is primarily an early transporter of the toxic compounds to the intestines, where they can be bound to fiber that helps transport them out of the body. Environmental toxins, including lipid (fat) soluble toxins, are broken into water-soluble components by bile to be excreted through the kidneys or colon.

Liver Detoxification

Detoxification refers to the process of excreting potentially harmful compounds that are both generated by the body and acquired through exposure to the environment. In the body, toxins are generated as by-products of cellular metabolic processes. Examples include dead and digested bacteria, hydrogen peroxide, cellular debris, and carbon dioxide.

The Environmental Protection Agency has determined that the amount of environmental toxins in the air, groundwater, and soil has increased significantly in the last 40 years. In fact, the use of pesticides has doubled every ten years since 1945. Americans are increasingly exposed to heavy metals, pesticides, fossil fuel emissions, sulfur oxides, hydrocarbons, and other harmful chemicals. The Environmental Protection Agency reports that traces of toxic chemicals can now be found in nearly every American.

Herbal Liver Support

One of the major components in Complete Liver Cleanse is its milk thistle extract, standardized to contain 80% silymarin, the plant’s most bioactive compound. Milk Thistle provides support, at a cellular level, for healthy liver function. A patented delivery system, known as the Phytosome process, provides superior absorption of the milk thistle extract.

Silymarin, a key compound found in milk thistle, is a mixture of flavonoids with a long history of liver support. Silymarin supports the health of Kupffer cells, specialized liver cells responsible for removing bacteria, old blood cells, and other foreign matter from the liver’s blood supply. Silymarin scavenges free radicals (superoxide anion radical and nitric oxide) produced by activated Kupffer cells, supports healthy leukotriene levels, and supports glutathione production that is used in detoxification.

Silymarin also supports the health of hepatocytes, highly versatile liver cells with unique physiologic functions. Studies of silymarin have demonstrated that it supports the health of the hepatocyte outer membrane, which is crucial to the liver’s detoxification processes. Silymarin also supports the healthy regenerative ability of the liver through support of protein synthesis in the hepatocytes.

Phytosome Process

A special, patented proves known as Phytosome enhances the absorption of milk thistle in Complete Liver Cleanse. The Phytosome process pairs herbal ingredients with phosphatidylcholine molecules. Phosphatidylcholine is a naturally occurring substance found in soybeans, egg yolks, and some vegetables. In the body, phosphatidylcholine is an important building block of cell membranes.

When milk thistle (or other herbs) are bound with phosphatidylcholine, the phosphatidylcholine molecule facilitates absorption through the intestines into the bloodstream. Research has shown increased blood and serum levels for phytosome herbs in comParison to the individual herb alone.

To test whether binding an herb with phosphatidylcholine increased its bioavailability, researchers gave volunteers identical amounts of either milk thistle alone, or milk thistle phytosome. The researchers then took blood sample from the participants and measured the level of silybin (a key compound in milk thistle). The measurements showed that silybin levels in participants taking the phytosome form of milk thistle were higher, and that silybin was detected for a longer time, than those who took milk thistle without the phytosome delivery system.

Other Herbal Liver Supportive Ingredients

Herbal extracts are often at their best when they are working synergistically – that is, when different constituents of each plant work together and support each other. Complete Liver Cleanse contains a variety of herbal extracts that have noted benefits for supporting the body’s healthy bile flow and free-radical scavenging effects. These ingredients provide a wide spectrum of liver supportive benefits.

For instance, dandelion root extract supports healthy bile flow from the gallbladder.

Burdock Root:

Burdock is originally native to Europe and Asia, but was introduced to North America, probably during colonial times. The plant is commonly found in the northern United States, and is very recognizable, with large, heart-shaped leaves. It has a long history of traditional use for gastrointestinal support.

Burdock root (Arctium lappa) supports the natural physiologic processes of organs involved in detoxification and elimination: notably, the liver, kidneys, and intestines.

Boldo:

Bolodo (pemus boldus) is a small evergreen native to South America, but naturalized to southern Europe. The leaves are considered the health supportive part of the plant. This herb has a long history of use in Chile, and became known in Western countries in the late 19th century.

In scientific studies, boldo appears to have strong free-radical scavenging ability, mostly attributed to the catechin and flavonoids content of its leaves. In a clinical study, boldo also appears to relax smooth muscle and support intestinal transit time.

Artichoke Leaf extract specifically supports healthy bile production in the liver and healthy gastrointestinal function in general. Research into artichoke’s gastrointestinal supportive properties has included at least three clinical trials. Artichoke’s role in supporting healthy cholesterol levels within normal limits has also been investigated.

Turmeric:

Turmeric (Curcuma longa) is a perennial shrub native to southern Asia with a long history as both a food ingredient and for health support.

More recently, turmeric has been investigated for its support of healthy bile secretion, and pancreatic and gastric function.

In a scientific study, dietary curcuminoids derived from turmeric supported healthy lipid metabolism and cholesterol levels already within normal limits.

Curcumin has also been shown in scientific studies to enhance the activity of glutathione S-transferase - an enzyme responsible for linking glutathione (one of the body’s natural antioxidants) with toxins to help remove them from the body. In this way, it provides additional support for healthy liver function.

Detoxification

Calcium d-glucarate:

The process of detoxification is the breakdown and excretion of substances that are no longer needed or may be harmful to the body. One of the ways in which the body excretes hormones and toxins is by binding them to glucuronic acid in the liver, and then excreting this compound in the bile.

However, this process can be disrupted by B-glucuronidase, an enzyme that is produced by intestinal bacteria. This enzyme has the ability to break (uncouple) the chemical bond established by glucuronic acid. This action releases the bound toxins, which are then reabsorbed into the body instead of being excreted.

Calcium D-Glucarate is the calcium salt of d-glucaric acid. It is found in both the human body, and in some plant sources, including broccoli and oranges.

Calcium d0glucarate enhances the body’s detoxification systems by inhibiting the actions of beta-glucuronidase. This helps decrease the portion of active compounds that could be hazardous to the body.

Phytosterols

Cholesterol is a waxy, fat-like substance that is vital to fat digestion, cell structure, nerve insulation and hormone production. Cholesterol comes from two sources: dietary or “exogenous” cholesterol absorbed in the intestine, and “endogenous” cholesterol formed mostly by the liver and stored in the gallbladder.

Cholesterol occurs in two forms known as lipoproteins. Lipoproteins act as transports that carry fat s to and from the cells.

High-density lipoprotein (HDL) carries low lipid density cholesterol (LDL) away from arterial walls and returns it to the bloodstream. LDL then travels back to the liver, which processes and eliminates it. While high levels of HDL cholesterol is desirable, high amounts of LDL cholesterol is not supportive of optimal health.

LDL-cholesterol is both synthesized in the body, or absorbed into the bloodstream through receptor sites in the intestines. Think of these receptors as “parking spaces” for cholesterol. As it happens, the liver can receive up to 500 mg per day of cholesterol from intestinal absorption. (It can also produce as much as 1000 mg per day).

One way to help reduce the absorption of LDL cholesterol molecules it to occupy their “parking places” in the intestines. Phytosterols in Liver Cleanse are essentially the “fat” of plants. They’re found in nuts, corn and rice and are some of the “good” fats associated with the benefits of olive oil, flaxseed oil and other healthy oils.

The structure of phytosterols is so similar to cholesterol that they fit perfectly in the specially-shaped intestinal parking spaces that LDL-cholesterol would normally occupy.

Taken with, or just before meals, phytosterols block the cholesterol receptor sites so that cholesterol is excreted from the body rather than absorbed. Phytosterols also have the additional role of helping promote healthy bile salt excretion in the intestines.

The phytosterol blend in Complete Liver Cleanse can help minimize the absorption of cholesterol from high-protein food sources, help retain healthy cholesterol levels that are within normal limits, and move bile sat through the digestive system.

Fiber and detoxification

Fiber plays a key role in the removal and excretion of intestinal toxins in detoxification. Only fibers that can effectively bind toxins will be successful in eliminating these harmful substances. Due to the unique benefits of individual fibers, the best binding, removal, and elimination effects are noted when combining different fiber types. Complete Liver Cleanse contains a combination of oat beta-glucan and konjac fiber that has been shown in scientific studies to bind to bile salts.

Dietary fibers are complex mixtures of cellulose, hemicellulose, pectin, mucilage, and gums, which are resistant to digestive fluids or enzymes – that is, they aren’t absorbed into the bloodstream. So, while fiber itself doesn’t necessarily provide nutrients, it does promote laxation and modulate gastric and intestinal physiology. Intestinal flora that normally reside within the colon utilize fiber as a medium for microbial fermentation, resulting in the synthesis of the vitamins, vitamin K and biotin, and the formation of short chain fatty acids, or SCFA.

SCFA have a simple, but important job: to be absorbed by the colon mucosa, increasing fecal matter bulk and providing energy. Fiber has been demonstrated in numerous clinical studies to provide support of gastrointestinal, cardiovascular, immune, and endocrine function health.

Complete Liver Cleanse also features two unique fibers to promote detoxification – konjac and oat beta-glucan.

Konjac:

Konjac, (Amorphophallus Konjac) is a tuber native to Asia, rich in glucomannan polysaccharide. This viscous material is made into a jelly, noodles and other foods. It has been used in Japan for at least a thousand years.

As a fiber, konjac has shown positive results maintaining healthy cholesterol levels within normal limits in clinical studies. This beneficial effect is due to konjac’s ability to boost excretion of bile acid.

Oat beta-glucan:

Oat beta-glucan has been a widely studied fiber source for supporting healthy cholesterol levels within normal limits.

In a randomized clinical study, oat beta-glucan showed support of healthy HDL/LDL ratios already within normal limits in individuals over a three week trial.

Closely linked to cholesterol, oat beta-glucan has also been studied for its support of healthy bile excretion.

Fiber has benefits beyond maintaining healthy cholesterol levels already within normal limits. It also contributes to healthy blood sugar levels already within normal limits. In a double-blind, clinical study, the oat beta-glucan fiber used in Liver Cleanse was shown to have 4 times higher viscosity than another high concentrate beta-glucan fiber.

Viscosity – the resistance to flow – is an important factor in beta-glucan, and all fiber. Water, for instance, would have a low viscosity, because it provides very little resistance to movement. Fiber, on the other hand, should have a higher viscosity in order to maximize its transit time through the GI tract, providing a gentle “scrubbing” on the intestinal walls. Therefore, the higher the viscosity, the greater the potential benefit.

RECOMMENDATIONS:

Three capsules in the morning and three capsules at bedtime for 14 days.

LABEL PRECAUTION:

Warnings: Do not use if you know or suspect you have an obstructed bile duct or problematic gallstones. If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children.



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Supplements for Sexual health!
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Date: April 17, 2007 02:35 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supplements for Sexual health!

Improving Sexual Performance Naturally

Sex. It’s everywhere. It’s on TV (a lot!). It’s in the books we read and the movies we watch. Even the radio seems a veritable hot bed of sex. (what would hard rock, soft jazz, or Motown classics be without songs about sex?) Magazines are full of sex and it’s not just the “naughty” ones with glossy centerfolds. From Sports Illustrated to Good Housekeeping, sex makes for titillating headlines and cover stories. In fact, 21st Century America seems to be awash in sex, except where it counts – in the bedrooms and love lives of married Americans.

No one really knows for sure how many of the 113 million married Americans are living as couples with DINS (dual income, no sex). Estimates range from 15 to 50 percent. Even couples who have sex fairly often feel like they’re not having enough sex or that it’s not as enjoyable as it was in the past, or both. And while women are stereotyped as the sex refusers and avoiders, surveys show that both women and men decline spousal advances fairly equally.

What’s really interesting about this lack of sexual activity in America, is that the very same thing is happening to husbands and wives residing in Paris and London, as well as Lisbon and Madrid. Research has shown that married couples who reside within Western civilized countries are much more likely to have unhappy sex lives than their counterparts living elsewhere in the world. That’s because the married couples residing in the rainforests of Brazil, the streets of Beijing, and the mountains of Tibet have access to powerful plant medicines that keep their sexual relationships healthy and happy. In fact, in China and India alone, over one billion men and women routinely incorporate plant medicines for healthy and satisfying sex.

As a medicine hunter, I have discovered effective plants and herbs al over the planet that really do improve orgasms in women and erections in men. Now it’s your turn. I’m going to teach you how to enhance your sexuality and introduce you to an entire arsenal of libido lifting plants to help make sex fun, vibrant, and satisfying for both you and your partner.

 

Q. These plants sound too good to be true. Do they really work?

A. Yes, they do. Part of their success is their ability to work with your body’s innate mechanisms for healthy sex. Good sex is much more than just stimulated body parts. But it’s a good place to start!

A man needs an erect penis that remains firm past foreplay and on into intercourse. He also needs to sustain that erection and experience forceful and pleasurable ejaculation when he and his partner are both ready for his orgasm. A woman needs to feel desire and feel desired for her nipples to be aroused, her clitoris stimulated, and her vagina lubricated – the basics leading to her orgasm.

Plants that enhance sex can help men and women obtain these bare necessities of sex. And unlike other supplements, you’ll know if the medicinal plant you’ve purchased is actually doing what it promised to do. You can’t really tell if the calcium supplement you take each day is making your bones stronger. But you will be able to tell pretty soon if Catuaba, for example, is increasing your sexual desire.

Q. Night after night, my husband falls asleep on the sofa. And the honest to goodness truth is that I’m too tired for sex, too. I love my husband and once upon a time I loved sex. But my job, the kids, those never-ending errands, and trying to keep up with the laundry are too exhausting. Is there a plant that can rev us up?

A. Many women are in the same sexless boat you’re sailing around in and they don’t like it any more than you do. In fact, women all over the world put their family’s needs before their own, leading to some very tired moms and wives.

Life’s demands can also impair sexual performance in men. Work stressors, family demands, and home maintenance result in fatigue and lack of energy. Men find that they have no energy left to devote to to sex at the end of the day.

But, over 80 percent of married couples in the world have at their disposal a health care system that integrates sex into their personal health and well being. For centuries, millennia actually, practitioners of traditional medicine have prescribed Maca and Rhodiola to reduce “sexual fatigue” in women and men who are just too tired to make love.

 

Sex Enhancing Plants for Men and Women

How They Work

Maca (Lepidum meyenii)

For the past several years in Peru, where the Maca plant grows, physicians have prescribed extracts from this plant to men with low libido and diminished erectile function, which excellent results. Recently researchers studying Maca have discovered two compounds they think are responsible for improved sexual stamina, namely the macamides and macaenes. It is these same compounds that help men and women obtain more frequent and more powerful orgasms.

Rhodiola Rosea

This hardy plant grows high in the mountains of Europe and Asia, enduring cold and snow and lack of sunlight for much of the year. Hoping to gain some of Rhodiola’s energy and stamina for themselves, early Siberians used extracts of the plants to boost strength and stamina. Not only did they have more energy, they discovered they had more sexual stamina, too.

 

Rhodiola is an adaptogen, a plant that helps us adapt to changes in life and the stresses of everyday life. When we’re stressed, our bodies shift into high gear causing a cascade of hormones to prevent and reduce harm. In cases of trauma (like car accident or surgery (or simply nature at work (such as childbirth), these hormones are necessary. However, when we experience stress that’s caused by work (your boss), or family (your teen-aged children), or personal struggles (your weight), this hormonal cascade can do more harm than good –causing fatigue, added weight gain, poor metabolism, and impaired sexual function.

 

Rhodiola helps make sure the hormonal cascade occurs when it’s needed, to protect our health, not harm it. The result is better energy, better vitality, and better sex!

 

Q. Since I had a baby four months ago, I have no desire for sex. This is making my husband pretty frustrated and me too, actually. I’d love to want sex again.

A. A married woman with a baby and a toddler or two can feel that her body isn’t really hers. So much for feeling sexy! While this fact can be a source of great pride and joy, it can also drain desire.

As women enter perimenopause – those years when they are still menstruating despite fluctuating estrogen levels – they often have no desire for sex. Since estrogen is the engine that drives women’s reproductive function, when it starts to go, sex goes too. Women who have reached menopause may find their minds wandering during sex. Pondering the car’s need for an oil change or if the milk in the refrigerator has reached its expiration date makes for pretty blah sex. It also makes it nearly impossible to achieve orgasm.

Once more, traditional medicine has some answers:

Sex Plants for Women

How They Work

Ashwagandha (Withania somnifera)

Just like Rhodiola, Ashwagandha is an adaptogen, possessing powerful sex-enhancing powers. And just like Rhodiola, Ashwagandha has been helping women boost their desire for sex. Long considered India’s most potent sex-enhancing plant, the country’s women have used Ashwagandha for years to rev up their sex drives.

Catuaba (Erythroxylum Catuaba)

Catuaba is a tree that grows in the dense, lush Brazilian Amazon, the largest tropical rainforest on Earth. For hundreds and hundreds of years, tribal peoples have used Catuaba bark to stimulate sexual desire. According to folk legend, the Tupi Indians discovered Catuaba bark’s sex-enhancing effects and passed the knowledge on to other rainforest tribes. Today, Catuaba is used worldwide by women desiring passionate sex.

Eleuthero (Eleutherococcus senticosus) extract

Sometimes called Siberian ginseng, Eleuthero is actually not a ginseng at all, only a distant cousin. This leafy shrub is native to Eastern Russia and the mountains of China and has been used by tribal peoples for over 2,000 years to eliminate sexual fatigue. Eleuthero is another adaptogen, invigorating sexual function and restoring balance to all body functions.

Q. My husband has a desire for sex, but sometimes it’s not enough. Even if we’re both in the mood, he can’t maintain his erection very long. It’s very frustrating for us both.

A. For men it’s often their equipment that lets them down. As men age, they find they can’t get an erection hard enough or keep an erection long enough to satisfy their partners and themselves.

While women can fake an orgasm if they’re tired, men have to perform every single time they have sex. Luckily, Mother Nature can help:

Sex Plants for Men

How They Work

Horny Goat Weed (Epimedium species)

This aptly named sex plant has been in use for over two thousand years, restoring sexual fire, treating impotence, and increasing production of semen. The green leaves of Horny Goat Weed are filled with numerous natural compounds, responsible for these sexual effects. Research shows that horny goat weed has activities very similar to the androgens, sex hormones that stimulate desire in men.

Yohimbe (Pausinystalia yohimbe)

Yohimbe is nature’s Viagra – it helps men attain firm erections. Not surprisingly, Yohimbe has been used for a long time as a fold medicine aphrodisiac. The bark contains Yohimbine, a compound known to stimulate engorged vessels within the penis and nerves of the lower spine. It’s no wonder Yohimbe has the well-deserved reputation as a superior sexual stimulant.

Panax ginseng

One of the most highly regarded plants in traditional Chinese medicine, Ginseng stimulates the central nervous system, invigorates the brain, increases resistance to stress and fatigue, and sharpens the mind. Ginseng is also used by millions of men to enhance libido and sexual vitality. In an erectile dysfunction study, men who took Ginseng had a 42% improvement in erectile function compared to placebo. Researchers theorize that ginseng increases nitric oxide in the penis, dilating the vessels of the corpus cavernosum - the very same mechanism that makes Viagra work.

Q. There are hundreds of supplements that claim to make men hard and women weak with desire. I’ve tried some of these, and they don’t do anything. When should I believe that the herbs and plan medicines you have discovered are nay better?

A. There are a lot of “snake oil” companies out there pitching products that promise to improve our sex lives but do absolutely nothing. One reason for this glut of useless supplements is simple demand. Men and women trying to make their sex lives better, are willing to give most products the benefit of the doubt and buy one or two. Sex sells – and even products that are purchased one time only will make big profits.

To get the most for your money, make sure the sexual supplement you are considering is from a well-respected manufacturer. Ask store staff, surf the Internet, and do some searching for the best nutraceutical companies. Make sure the herbs are standardized and that the extracts are concentrated fro optimal benefit.

Q. Are these sex-enhancing plants safe?

A. Despite years of use by practitioners of traditional medicine, significant adverse effects have not been reported for most sex-enhancing plants. However, men who have already been diagnosed with certain health conditions such as high blood pressure, thyroid disease, prostate problems, or other illnesses should use caution when selecting any health supplement. The same advice applies to women, especially women who are pregnant or nursing. And always remember to keep your doctor informed about the supplements you are using, especially if you are also taking prescription drugs. But the sex-enhancing plants have been traveling on planet Earth for a long, long time. And hopefully they’ll be here for lot longer, continuing to work effectively and go about their business of safely improving orgasms and erections and making sex great for men and women all over the world.

Q. OK, exactly how did early native healers figure out which plants improve sex? Was it just simple trial and error?

A. It does seem pretty remarkable that tribal peoples have discovered the right plants to treat diseases and improve health without modern day scientific advances.

From my many years as a “medicine hunter” in rainforests and grasslands and marshes and mountains, I’ve learned that healing plants exist for virtually every health need. It’s up to the medicine man or women to put the plant into practice. These healers have been able to do this successfully for thousands of people, by intensively studying and working with the plants. By putting themselves into the plant’s world, becoming part of the world around them, native healers have intuitively discovered which plant helps which disease. It wasn’t mere luck that brought all those plants and all those healers together. It was the natural and spiritual connection existing between the two.

Q. Are there other “natural” remedies we can use to improve our sex lives?

A. The easiest way to naturally enhance your sex life is to practice, practice, practice! Because if you don’t use it, you might lose it. Studies have shown that couples in the Amazon rainforest as well as couples in the concrete jungle of New York City have better sex lives if thy make sex a priority. All the sex-enhancing plants in the world are useless if the men and women taking them don’t put them to the test.

Men who smoke need to quit. Research has shown that cigarettes send men’s sex lives up in smoke. Men who smoke more than 20 cigarettes daily have a 60 percent higher risk of erectile dysfunction compared to men who never smoked. That’s because smoking decreases blood flow making it difficult for men to obtain an erection.

And finally, since sex is a visual and tactile endeavor, there are quite natural and creative ways to give it a boost. Visually stimulating images can arouse even the tiredest of the tired. Premiere Magazine recently compiled a list of the most erotic movie sex scenes ever. You don’t have to feel embarrassed when renting these movies (as you might with pornography) at the video store and they are guaranteed to light up your life:

1.      Diane Lane and Oliver Martinez making love in UNFAITHFUL (2002)

2.      Hilary Swank pleasuring Chloe Sevigny in BOYS DON’T CRY (1999)

3.      Brad Pitt and Claire Forlani making love in MEET JOE BLACK (1998)

4.      Leonardo DiCaprio drawing Kate Winslet in the nude in TITANIC (1997)

5.      Sharon Stone uncrossing her legs while she is being interrogated in a room full of en in BASIC INSTINCT (1992)

6.      Patrick Swazye and Demi Moore in the pottery secene early on in GHOST (1990)

7.      Michael Douglas and Glenn Close having sex in an elevator in FATAL A TTRACTION (1987)

8.      Mickey Rourke caressing Kim Basinger’s body with an ice cube in 9 1.2 WEEKS (1986)

9.      William Hurt and Kathleen Turner having sex in BODY HET (1981)

10.  Julie Christine and Donald Sutherland making love in DON’T LOOK NOW (1973)

11.  Rita Hayworth flipping back her hair and singing “Put The Blame on Mame” in FILDA (1946)

One Important Last Point

Sex always has consequences. And improving your sex life does not eliminate the requirement to practice it responsibly. Sexually transmitted diseases, hepatitis, and HIV/AIDS must be prevented, pregnancy must be considered and consent between partners must exist.

Conclusion

Sexual activity keeps us connected – both tangibly and spiritually to our heart’s desire. It helps us feel secure and well loved and adds to our self esteem. In other words, good sex is important to good life.

But all of us need a little help now and then. Sex-enhancing plants that have been used for thousands of years by millions of people provide that help. You can have actual sexual healing with effective sexual supplements and maybe find out what you’ve been missing.

After all, 80 percent of the world’s married couples can’t be wrong!



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EpiCore Benefits
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Date: April 09, 2007 05:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: EpiCore Benefits

Benefits

EpiCor® is a unique and novel dietary supplement used for support of immune health, with a fascinating history of discovery. In 1943, a company in Cedar Rapids, Iowa called Diamond V Mills, Inc. began manufacturing and selling a fermentation product from the yeast Saccharomyces cerevisiae, the same yeast used in bread and beer making. The product was and still is used as an additive for animal feed to help improve digestion as well as overall health in animals. It has been on the market for over 60 years.

Interestingly, when the company became self-insured, they became aware of unusually low rates of illness in employees that worked in the manufacturing plant for this animal product. This led to very low increases in their insurance premiums over the years compared to other companies, saving them quite a lot of money. Hence they began to investigate what might be the cause of the “healthfulness” of the employees at the fermentation plant. This investigation and subsequent research studies led to the formation of a new company called Embria Health Sciences, which now produces EpiCor® as a supplement for humans to support immune system health.1 Doctor’s Best® is proud to now offer the benefits of EpiCor® to its customers.

Beneficial Support of the Immune System and Activation of Natural Killer (NK) Cells in vitro*

A comParison study was performed on blood from 10 fermentation plant workers compared to that from 10 age and gender matched controls. The fermentation plant workers had several immune cell parameters that appeared superior to the control group. These included decreased levels of CD8 cells resulting in significantly increased CD4 to CD8 ratios, significantly improved cytotoxic natural killer (NK) cell activity even though total NK cells were decreased in number, higher killing efficiency of NK cells, significantly increased levels of secretory IgA, increased numbers of EpiCor™ specific antibodies, higher levels of red blood cell intracellular glutathione, and significantly lower levels of immune complexes. These results represent benefits on various cellular players of both the specific and innate parts of the immune system.1,3,4

NK cells are one of the first lines of defense used by the immune system. An in vitro study performed on human cells showed that NK cells were activated after incubation with EpiCor®, as evaluated by expression of the CD69 activation marker. The CD25 marker (IL-2 receptor) was also induced in the NK cells, although to a lesser degree.1,2 B cell activation was also noted through increased expression of CD80 and CD86 markers.2 Immediate increases in calcium levels were evident in peripheral blood mononuclear cells after exposure to EpiCor®, suggesting increased activation through calcium regulation.2

High Metabolite Immunogen*: Nutrient Make-up

Production of EpiCor® utilizes the common and harmless bakers or brewers yeast Saccharomyces cerevisiae in a patented process called MetaGen4™, a multi-stage fermentation and drying process. It differs from other yeast products in that it contains both the yeast itself as well as the metabolites or “nutrilites” formed by the fermentation process, which are present in the media.1 Together the media containing the metabolites and the yeast are dried to form EpiCor®. Analysis of EpiCor® reveals that it contains a mixture of natural polyphenols, phytosterols, beta-glucans, mannan oligosaccharides, fiber, trace amounts of B vitamins and minerals, as well as a host of other nutritional compounds.1,2

Beneficial Antioxidant Activity*

EpiCor® was tested for antioxidant activity in an in vitro assay called the Oxygen Radical Absorbance Capacity assay (ORAC). In this assay, EpiCor® was shown to have a total ORAC antioxidant level of 610 micromol TE (tocopherol (vitamin E) equivalents) units (ORAC units) per gram dry weight, which soared above other high antioxidant level foods such as cranberries (93 ORAC units per gram dry weight) and blueberries (62 ORAC units per gram dry weight).1,3,5

In another study, freshly isolated human neutrophils were treated with EpiCor® followed by the free radical generator hydrogen peroxide. Cells were treated with a dye that fluoresces when attacked by free radicals. Those cells treated with EpiCor® showed decreased fluorescence intensity compared to control cells not treated with EpiCor®, verifying antioxidant activity in vitro.2

Safety

Numerous safety tests have been conducted on EpiCor®, revealing an extremely safe profile. Animal studies performed by a leading toxicology laboratory showed no indication of any toxic effects of EpiCor®. An acute oral toxicity study on 20 rats showed that the product was safe when given to rats at a single oral dose of 2000 milligrams per kilogram of body weight (equivalent to a human ingesting 280 capsules at once). After 2 weeks the rats showed no clinical symptoms, no deaths, no abnormalities in body weight, and no gross pathological changes. The same safety results were found in a subchronic toxicity study where rats were given up to 1500 milligrams daily for 90 days (equivalent to a human ingesting up to 210 capsules daily for 1.5 years). Again, absolutely no signs or symptoms of toxicity were noted in these animals.1,3

In addition, a standard bacterial reverse mutagenicity test (AMES test) as well as a mammalian cell mutation assay using mouse lymphoma cells revealed no evidence of any increase in mutation rates after exposure to EpiCor®. EpiCor® also showed no evidence of mitogenicity (inducing increased cell division) in a human lymphocyte proliferation assay. This suggests that EpiCor® does not cause over-reactivity of cells1,3.

The effect of EpiCor® on specific liver enzymes CYP1A2 and CYP3A4 (enzymes involved in metabolizing certain drugs and other compounds) was assessed. Immortalized hepatocytes (liver cells) were treated with various concentrations of EpiCor® and compared to both positive and negative controls. EpiCor® did not increase the expression or activity of the liver enzymes, suggesting that it may not affect the metabolism of other substances or medications metabolized by these enzymes if they are taken simultaneously. It also did not appear to be toxic to the cells as measured by lactate dehydrogenase assays and microscopic analysis.1

Lastly, EpiCor® was tested for safety in humans in an open label study on 15 adult men and women given a single 500 milligram dose for 30 days. On various days throughout the study vital signs were monitored, and blood and urine samples were analyzed. No clinically relevant abnormal effects on the participants were found1.

 

EpiCor® also currently has received self-affirmed Generally Regarded as Safe (GRAS) status by an expert panel that included eminent toxicologists1.

 

EpiCor® is a novel compound with an incredibly unique composition that has been shown to enhance immune system function.*

Suggested Adult Use: Take one capsule daily with or without food.

 

 

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

Scientific References

1. Embria Health Sciences

2. Hart et al. A new Saccharomyces cerevisiae based product has anti-inflammatory effects while specifically activating human NK and B lymphocyte subsets. Unpublished study, personal communication.

3. Schauss AG, Jensen G, Vojdani A, Financsek I. After decades of ingestion by farm animals, the discovery of a yeast fermentate with unexpected significant immune modulatory activity when consumed by humans. [abstract] Journal of the American College of Nutrition, 2006; 25(5): 465.

4. Schauss AG, Vodjani A. Discovery of an edible fermentation product with unusual immune enhancing properties in humans. [abstract] FASEB J, 2006; 20(4):A143.

5. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem 2004 Jun 16;52(12):4026-3



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Peppermint Oil for IBS
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Date: March 24, 2007 11:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Peppermint Oil for IBS

Irritable bowel syndrome (IBS) is a painful and frequently frustrating disorder of the intestines that’s often difficult to treat. Fortunately, there are scientifically studied natural products that effectively reduce the distressing symptoms of IBS.

Q. What is IBS?

A. IBS causes crampy pain, gassiness, bloating, and alterations in bowel habits. IBS is termed a functional disorder, because when the colon is examined, there is no visible sign of disease. While IBS causes significant pain and distress, no actual damage is occurring in the intestines.

There is a wide variability in IBS. Symptoms may be mild and fairly well tolerated. Or, the pain, discomfort, and bowel dysfunction may be disabling, limiting social interactions, employment, or travel.

While some individuals with IBS have diarrhea (frequent, loose stools with an urgent need to move the bowels), others have constipation (hard, infrequent stools that are difficult to pass). And, still others may experience both. Individuals with IBS also may have painful abdominal cramps and feel an urgent need to move the bowels, but are unable to do so.

Q. What causes IBS?

A. The small intestine receives digestive material from the stomach and delivers it to the large intestine (colon). About two quarts (2,000 ml) of digestive material enter the colon from the small intestine every day. The colon absorbs water and salts from the material, which is progressively moved through the colon. This progressive movement continues until most of the fluid and salts are absorbed into the body and stool is formed. The stool passes to the left side of the colon, where it is stored until a bowel movement occurs.

Because researchers haven’t been able to find actual damage in the colon, it once was suggested that individuals with IBS have emotional problems or are overly susceptible to stress. While stress may cause symptoms of IBS to intensify, it doesn’t cause the condition.

Recent study has determined the colon muscle of an individual with IBS spasms after only mild stimulation. It’s thought the symptoms of IBS are produced by hyperactivity of the intestines. In other words, the intestines of individuals with IBS are more reactive to stressors and diet than usual. Almost everyone has experienced abdominal queasiness in response to everyday stress or certain foods. This may result in a brief bout of diarrhea or an upset stomach. However, this response is exaggerated in individuals with IBS.

Q. How prevalent is IBS?

A. IBS is very common. In fact, it’s one of the most frequent problems seen by family physicians. It’s the most common disorder diagnosed by gastroenterologists (physicians specializing in the treatment of digestive disorders). The overall prevalence rates range from 10% to 20% of the general population in most industrialized countries. As a result, the pain and disabling symptoms associated with IBS result in significant socioeconomic costs, as wall as reduction in quality of life for many individuals.

Q. What are the symptoms of IBS?

A. Normal bowel function varies from person to person. Some people move their bowels daily, while others may only have two to three stools a week. A normal bowel movement is soft, formed, and is easily passed without cramping or pain.

IBS, however, causes abdominal cramps and pain, which are often severe and disabling. Bowel movements may be irregular and alternate between diarrhea and constipation. The diarrhea may be quite loose and watery. Mucous may be passed. There is often much straining, urgency, and feeling of incomplete evacuation (emptying). Abdominal bloating and passing of gas is common. Nausea, lack of appetite, heartburn, and belching may also be present. Sleep may be disrupted resulting in fatigue and lack of energy. Understandably, persons with IBS often feel anxious and depressed.

Diagnosis of IBS is usually based on the continuous presence or recurrence of these symptoms for at least three months. Other intestinal conditions must be ruled out. These include Chron’s disease, ulcerative colitis, inflammatory bowel disease, colon cancer, inflammatory conditions of the stomach or pancreas, ulcers, infectious disease, or gastroesphageal reflux disease.

Q. Are there clinically demonstrated natural alternatives to the over-the-counter drugs prescribed by my doctor?

A. Yes, both enteric-coated peppermint oil and clown’s mustard (in combination with other herbs) have significant scientific research behind them. Both have been demonstrated to benefit individuals with IBS.

Q. What is clown’s mustard and what does it do?

A. The scientific name for clown’s mustard is Iberis amara. Other names for this herb are wild candytuft and bitter candytuft. Clown’s mustard is a white-flowering plant from Spain, where it grows in dry soil on hillsides and in cornfields. It is also grown in Britain, France, and the United States. Iberis amara is a member of the Brassicaceae family. Iberis refers to its place of origin, the Iberian Peninsula. Amara means bitter. The key components of clown’s mustard are glycosides and flavonoids that have specific actions on gastrointestinal tract tone.

Q. Is there scientific evidence that clown’s mustard benefits people with IBS?

A. There has been very impressive research on clown’s mustard (in combination with other herbs). And, it has been used with great success in Germany for many years to treat IBS and other gastrointestinal diseases.

In a study of an herbal combination containing clown’s mustard, 20 patients were given the herbal combination for three to 32 days. They all had been diagnosed with chronic functional disorders for at least one to 20 years. The symptoms the patients experienced included pressure and pain in the abdomen, belching, heartburn, vomiting, nausea, fullness, lack of appetite, constipation, and diarrhea. The patients have been treated for their problems with a variety of antacids, anti-spasmodic agents, and motility-inducing substances. For the purposes of the study, the patients stopped taking these medications and received treatment only with the herbal combination.

Abdominal pressure and pain in the abdomen was the most common of all the experienced symptoms, with 11 of the patients rating it as severe. After six days of treatment, only sic of the patients continued to rate their abdominal pain and pressure as severe. After two weeks, this symptom had completely resolved for 16 of the patients. Diarrhea had been rated as severe in five of the patients. By day 14, only one patient continued to have moderate diarrhea.

Medications prescribed and taken for cardiovascular diseases, arthritis, and autoimmune diseases often cause gastrointestinal problems. Because these conditions are chronic, these medications must be taken for a long time, often for life. With long-term use, these medications can cause erosion of the stomach lining and actual ulcers. Many of these medication-caused symptoms are similar to IBS symptoms: pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Most, if not all, of the individuals who have gastrointestinal problems caused from medications experience two or more of these IBS symptoms.

Forty patients who were taking medications for various types of cardiovascular disease and arthritis, and who are experiencing gastrointestinal problems related to their medications, were enrolled in a study. These symptoms included pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Twenty patients received clown’s mustard combined with other herbs that support gastrointestinal motility. Three days after the trial started, a significant improvement of all s symptoms was noted in those taking this combination. By day 14, abdominal pressure and pain, nausea, and heartburn were completely eliminated in the herbal combination group. Several other clinical trials that were conducted in Germany report similar results.

Q. How does this herb compare to prescription drugs?

A. A study compared clown’s mustard (combined with other herbs) to Reglan (metoclopramide), which is frequently prescribed to reduce the symptoms of IBS. While metoclopramide is a very effective medication, it also has numerous side effects. Metoclopramide can cause fatigue, anxiety, agitation, jitteriness, insomnia, yellowing of the skin or eyes, changes in vision, hallucinations, and seizures. Because of these serious side effects, metoclopramide must not be taken longer than 12 weeks.

In comParison study, 77 subjects were randomized to receive treatment of either clown’s mustard in a combination with other herbs, or metoclopramide. All subjects had pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. The subjects took 20 drops of their assigned treatment after meals three times daily. The duration of treatment was one to two weeks.

In both groups, a parallel improvement of all symptoms was observed. At no point in the study was a statistically significant difference in symptoms found. Both treatments significantly reduced pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. In short, both metoclopramide and the clown’s mustard herbal combination worked well at reducing the symptoms of IBS.

However, side effects occurred more frequently and severely in the metoclopramide group. Given the lack of differences noted between the products at reducing symptoms of IBS, it would seem sensible to choose the treatment with the fewest reported side effects and no limits on duration of use.

Q. What evidence supports use of enteric-coated peppermint oil capsules for IBS?

A. Peppermint oil has been shown to relax intestinal smooth muscle. In Great Britain, peppermint oil is currently being prescribed for IBS by physicians and it has been used as a digestive aid and to soothe upset stomachs for generations.

Peppermint oil has also been studied for use in an important examination of the colon. A colonoscopy is a procedure of viewing the interior lining of the large intestine (colon) using a colonoscope, a slender, flexible, hollow, lighted tube about the thickness of a finger. A study published in the New England Journal of Medicine supports the idea that even people who are not at risk for colon cancer should have this test. The American Cancer Society recommends that men and women at average risk of colon cancer should have a colonoscopy every 10 years, beginning at age 50.

During a colonoscopy, individuals are sedated and almost no discomfort is experienced. The insertion of the colonoscope into the rectum and up through the colon causes some spasming. This is a natural and expected event and the physician performing the exam administers medications that effectively reduce the spasms.

A recent study compared the use of peppermint oil and commonly used medications to reduce the colonic spasming in colonoscopy. The peppermint oil was introduced directly into the colon. Effective reduction of colon spasming was observed in 88% of the patients.

In a critical review and meta-analysis of peppermint oil for irritable bowel syndrome published in The American Journal of Gastroenterology, eight randomized controlled trials were identified. The studies collectively showed peppermint oil is superior to placebo in improvement of the symptoms of IBS. Because of the good results of these trials, the authors of the review urged additional study of peppermint oil in IBS.

However, straight peppermint oil is rapidly absorbed into the blood stream from the stomach. In recent studies comparing enteric-coated peppermint oil capsules and non-enteric coated oil, both preparations provided effective symptom relief. However, the studies concluded the enteric-coated capsules delivered the benefit of the peppermint oil directly to the intestines. In the treatment of IBS, enteric-coated supplemental peppermint is most definitely preferred.

In fact, an enteric-coated peppermint oil capsule containing rosemary and thyme is extremely effective in the treatment of IBS. All three of these oils are classified as volatile oils, derivatives found in plants that impart taste and aroma. The combination of peppermint, thyme, and rosemary oils in enteric-coated capsules provides significant relief in IBS-related pain.

Q. Can clown’s mustard and other herbs be taken with enteric-coated peppermint oil?

A. Yes, peppermint oil capsules and clown’s mustard can be used together. However, depending on the symptoms, individuals with IBS may want to start with one supplement and then add the other if needed.

Q. How do consumers find these formulas?

A. Fortunately, herbal combinations containing clown’s mustard and enteric-coated peppermint oil capsules are both available at health food stores, natural product supermarkets, pharmacies, and from health professionals. Most knowledgeable sales personnel and health professionals can direct consumers to the most effective products.

Q. What should customers look for when purchasing peppermint oil?

A. As mentioned before, enteric coating of the peppermint oil is extremely important. The coating prevents the oil from being absorbed in the stomach. The enteric coated-capsule moves through the stomach to the small intestine and eventually to the colon, where it is released for maximum benefit.

Q. What is the dosage for peppermint oil?

A. The German Commission E approved peppermint oil for the treatment of irritable colon. In enteric-coated form, the Commission E recommends 0.6 ml per day. Enteric-coated peppermint capsules are available.

Q. Are there side effects or other contraindications?

A. Sometimes, the enteric-coated peppermint oil capsules may cause a transient burning sensation in the rectum when moving bowls. Reducing the dose will correct this.

Individuals who must refrain from alcohol should not take clown’s mustard in an herbal tincture, which may contain alcohol.

Q. What else can IBS patients do to feel better?

A. Food allergies or food intolerance may be associated with IBS. Dairy products and certain grains may trigger a painful episode of IBS. Determining those foods that initiate the problems and eliminating them from your diet can be very helpful.

Many people report their symptoms occur after a meal. Hyperactivity of the intestine of IBS is the response. Often, the strength of this response after a meal is in direct relation to the number of calories and he amount of fat in the meal. Reducing saturated fat, limiting calories, and increasing fiber intake may be helpful.

Stress also stimulates the intestinal hyperactivity. Relaxation training may reduce some IBS symptoms. Listening to therapeutic audiotapes, hypnosis, counseling, and biofeedback all have been shown to improve the healing response in persons with IBS.

Conclusion

IBS can be painful and frustrating, capable of causing much distress. While currently there is no cure for IBS, the symptoms can be managed. The pain, abdominal discomfort, and bowel problems of IBS all respond well to treatment with the use of key herbs, including clown’s mustard, and enteric-coated peppermint oil. These herbal combinations can be both effective and safe in treating IBS. Clown’s mustard and enteric-coated peppermint oil are both effective front-line natural alternatives for IBS treatment.



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The Fizzy Comparison (Airborne Vs Wellness Fizz)
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Date: February 26, 2007 03:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Fizzy ComParison (Airborne Vs Wellness Fizz)


The Fizzy ComParison

Airborne Ingredients

•Vitamin A (palmitate)5000 I.U.
•Vitamin C (ascorbic acid)1000 mg
•Potassium (bicarbonate)75 mg

•Magnesium (sulfate)40 mg
•Vitamin E (acetate)30 I.U.
•Zinc (sulfate)8 mg
•Riboflavin2.8 mg
•Manganese (gluconate)3 mg
•Selenium (amino acid chelate) 15 mcg

•Herbal Extract Blend350 mg

(Lonicera, Forsythia, Schizonepeta, Ginger, Chinese Vitex, IsatisRoot, Echinacea)

•Amino Acids 50 mg

(L-Glutamine, L-Lysine HCL)

Also Contains: Sorbitol, Mineral Oil, Sucraloseand Acesulfamepotassium (artificial sweetener)

Wellness Fizz Ingredients

Vitamin A (as beta carotene) 5000 I.U.

•Vitamin C (ascorbic acid)1000 mg
•Potassium (bicarbonate)99 mg
•Vitamin E (succinate)30 I.U.

•Zinc (gluconate)12 mg
•Selenium (sodium selenite) 40 mcg
European Elderberry Ext (5% Flavonoids)200 mg
•Yin Chiao Extract 10:1 Complex 170 mg

(Forsythia, Japanese honeysuckle, Platycodon, Chinese Mint, Lophatherum, Chinese Licorice, Schizonepeta, Soy bean, Burdock, Phragmites)

•Echinacea purpureart. Extract (1.5-1) 100 mg

•Boneset Ext (4:1)30 mg
•Horehound Ext (4:1) 30 mg
•IsatisRt. Ext (4:1) 20 mg
•Isatisleaf Ext (4:1) 20 mg
•Elecampane Rt. Extract (4:1) 20 mg

Also Contains:Stevialeaf, natural flavors, honey

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Scientific References
TopPreviousNext

Date: February 11, 2006 09:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Scientific References

Scientific References 1. Toyoda-Ono Y, Maeda M, Nakao M, Yoshimura M, Sugiura-Tomimori N, Fukami H. 2-O-(beta-D-Glucopyranosyl)ascorbic acid, a novel ascorbic acid analogue isolated from Lycium fruit. J Agric Food Chem. 2004 Apr 7;52(7):2092-6.

2. Breithaupt DE, Weller P, Wolters M, Hahn A. ComParison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. Br J Nutr. 2004 May;91(5):707-13.

3. Cheng CY, Chung WY, Szeto YT, Benzie IF. Fasting plasma zeaxanthin response to Fructus barbarum L. (wolfberry; Kei Tze) in a food-based human supplementation trial. Br J Nutr. 2005 Jan;93(1):123-30.

4. Wu SJ, Ng LT, Lin CC. Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos. Phytother Res. 2004 Dec;18(12):1008-12.

5. Zhao H, Alexeev A, Chang E, Greenburg G, Bojanowski K. Lycium barbarum glycoconjugates: effect on human skin and cultured dermal fibroblasts. Phytomedicine. 2005 Jan;12(1-2):131-7.

6. Gan L, Zhang SH, Liu Q, Xu HB. A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells. Eur J Pharmacol. 2003 Jun 27;471(3):217-22.

7. Gan L, Hua Zhang S, Liang Yang X, Bi Xu H. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int Immunopharmacol. 2004 Apr;4(4):563-9.



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Olive Leaf Extract - for immune support
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Date: January 02, 2006 10:11 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Olive Leaf Extract - for immune support

“STANDARDIZED HERBS FOR IMMUNE SYSTEM SUPPORT”

Olive Leaf Extract

  • Nature’s Antibiotic
  • Standardized Herbal Extract
  • Natural Immune System Support
  • Potent Free Radical Scavenger

References
1) Balch, Phyllis A.; Prescription for Herbal Healing; Avery, Penguin Putnam, 2002
2) Walker, Morton; Nature’s Antibiotic: Olive Leaf Extract; Kensington Books, 1997
3) Walker, Morton; Olive Leaf Extract: The New Oral Treatment To Counteract Most Types Of Pathological Organisms; Explore!, Vol. 7, No. 4, 1996 4) Bisignano, G. et. al.; On the In-vitro Antimicrobial Activity of Oleuropein and Hydroxytyrosol; J. Pharm. Pharmacol., 1999, 51: pp. 971-974
5) Stupans, I. et. al.; ComParison of Radical Scavenging Effect, Inhibition of Microsomal Oxygen Free Radical Generation, and Serum Lipoprotein Oxidation of Several Natural Antioxidants; J. Agric. Food Chem., 2002, 50, pp. 2464-2469

* This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.



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Glucosamine & Chondroitin - JOINT HEALTH
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Date: December 22, 2005 09:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine & Chondroitin - JOINT HEALTH

  • Supports Healthy Joint Structure and Function
  • Supports Mobility and Ease of Movement

References:
1) Balch, James F. et. al. ; Prescription For Nutritional Healing 3 rd rd rdPrescription Edition Edition ; Avery; Penguin Putnam; 2000
2) Benedikt, H.; Glycosaminoglycans And Derivatives For Treatment Of Arthritis; Chiropractic Products, May 1997, pp. 92-95
3) Reginster, Jean Yves et. al.; Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial; The Lancet, 2001, Vol. 357, No. 9252 4) Bassleer, C. et. al.; Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro; Osteoarthritis and Cartilage, 1998, 6, 427-434
5) Drovanti, A. et. al.; Therapeutic Activity of Oral Glucosamine Sulfate in Osteoarthritis: A Placebo-Controlled, Double-Blind Investigation; Clinical Therapeutics, Vol. 3, No. 4, 1980, pp. 260-272
6) Morreale, P. et. al.; ComParison of the Antiinfl ammatory Effi cacy of Chondroitin Sulfate and Diclofenac Sodium in Patients with Knee Osteoarthritis; Journal of Rheumatology, 1996, 23:8, pp. 1385- 1391



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Pomeratrol™ Fact Sheet
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Date: December 19, 2005 09:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pomeratrol™ Fact Sheet

Pomeratrol™ Fact Sheet

Neil E. Levin, CCN, DANLA 9/28/04

USER: Those needing antioxidant protection; People with a family history of cell growth abnormalities; Anyone concerned with aging

KEY INGREDIENT(S): Pomegranate fruit standardized extract 200 mg. (Punica granatum) containing 80% total polyphenols, including 40% Ellagic acid, Resveratrol (100% trans-resveratrol) 20 mg. from a blend of Japanese knotweed root extract (Polygonum cuspidatum) and grape skin extract (Vitis vinifera)

POTENTIAL BENEFITS: Ellagic acid is a polyphenol compound found in raspberries, strawberries, pomegranates, and other fruit. It has been shown to normalize cell death of abnormal cells, a process called apoptosis. This enhances the body’s cell growth control system by providing an important plant substance. It may bind to DNA to prevent damage to this all-important genetic material. This is a key step in preventing cell damage that leads to signs of aging.

The American Cancer Society says that research in animal and laboratory models has found that ellagic acid inhibits the abnormal growth of certain cells. Research at Ohio State University indicates that berries typically contain a few milligrams per ounce of ellagic acid, the actual level varying quite a bit from variables such as species, variety and growing conditions.

Resveratrol is an antioxidant compound that is a phytoestrogen, or plant estrogen, which is protective of hormone-mediated cells in the body. Resveratrol is a potent antioxidant if stabilized. If not stable, it may quickly metabolize out of the body. This compound is believed responsible for some of the beneficial effects of moderate red wine drinking on the cardiovascular system. Resveratrol is also considered to be beneficial to smokers’ lung tissue if it is stabilized to last long enough in the system to be transported there. Resveratrol is also an inhibitor of the COX-2 inflammatory enzyme and encourages cell death (apoptosis) of abnormally growing cells. In insect experiments resveratrol even repaired DNA, leading to a longer life for healthy cells even as it helped get rid of unhealthy cells. Again, this ability to protect cells and help the body rid itself of abnormal cells is a key factor in preventing signs of aging. One liter of red wine contains between 1.5 and 3 mg. of resveratrol.

OTHER IMPORTANT ISSUES: Resveratrol is a difficult substance to stabilize. Because of the difference between resveratrol produced in the oxygen-poor environment in red wine and the form of resveratrol in unstabilized supplements, it has long been thought that resveratrol supplements were not very effective in comParison with wine. Knowing the importance of how a resveratrol supplement is metabolized, Now’s scientific staff has recently developed a special technique of stabilizing this compound in order to have an antioxidant effect closer to drinking a good glass of wine. While both trans and cis forms of resveratrol are naturally occurring, most of the recorded health benefits are attributed to the trans form. Now’s Pomeratrol provides trans-resveratrol.

DOSE: One capsule per day. Resveratrol has been used safely in studies at doses equivalent to 500 mg./day.

COMPLEMENTARY PRODUCTS: Other antioxidants and plant compounds: Vitamin C, pycnogenol, grape seed extract, and alpha lipoic acid.

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. There are some indications that resveratrol is a mild anticoagulant ("blood thinner"), and it also may help keep blood vessels to remain open and flexible. Caution should be used by those on blood-thinning drugs. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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FRUCTOSE
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Date: December 17, 2005 12:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: FRUCTOSE

FRUCTOSE

Fructose - Fructose is naturally occurring and also present in many fruits and vegetables. In fact, many refer to it as fruit sugar. In comParison to crystalline table sugar, fructose is highly fermentable and has a much lower glycemic rating than other simple sugars. This makes it suitable for many diabetics because unlike table sugar, it won’t trigger a large insulin spike. And despite its lower GI rating, fructose is approximately 50% sweeter than table sugar.



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ERYTHRITOL
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Date: December 17, 2005 10:45 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ERYTHRITOL

ERYTHRITOL

Erythritol - Since the early 1990’s, the popularity of this white crystalline sugar alcohol has steadily increased, and is now becoming the norm among many consumers and businesses alike. With a sweetness that is approximately 70% that of sucrose, a non-hygroscopic texture to prevent clumping and easy digestibility, it’s no surprise that so many have turned to this completely safe polyol. In addition, Erythritol is completely safe for teeth, extremely low in calories, won’t raise blood sugar levels, has zero “impact” carbohydrates and is one of the most easily digested of all sugar alcohols.

Erythritol Natural Sweetener

Many of you have been made well aware of the many dangers imposed by the over-consumption of conventional sugars and artificial sweeteners. So have we. And that’s why we’re so excited to introduce new Erythritol. Since the early 1990’s, the popularity of this low-calorie, white crystalline sugar alcohol has steadily increased, and is now becoming the norm among many consumers and businesses alike. With a sweetness that is approximately 70% that of sucrose, a non-hygroscopic texture to prevent clumping and easy digestibility, it’s easy to see why so many are turning to this completely safe polyol.*

Low Calorie

One of Erythritol’s most unique characteristics is its incredibly low caloric content. While polyols are generally known for being low calorie by nature, Erythritol exemplifies this characteristic, and contains just 0.2 calories per gram.

Safe for Teeth

Erythritol is non-cariogenic, and does not metabolize the oral bacteria that break down sugars and starches needed to produce the acids that lead to cavities and decay. In fact, the FDA recently released a qualified health claim stating that polyols including Erythritol “do not promote tooth decay”.*

Won’t Raise Blood Sugar

Several studies have suggested that Erythritol won’t raise blood sugar or insulin levels, and may therefore be a safe alternative to sucrose-based foods designed especially for diabetics.*

Easily Digested

Based on the small size and unique molecular structure of Erythritol, it is easily absorbed by the small intestine. As a result, gas and laxation are far less likely in comParison to sucrose.*

Zero Impact Carbs

As one of only two polyols that carry a glycemic index of zero, Erythritol has zero “impact carbohydrates”.*

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Butterbur Extract Fact Sheet
TopPreviousNext

Date: December 08, 2005 04:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Butterbur Extract Fact Sheet

Butterbur Extract Fact Sheet

Neil E. Levin, CCN, DANLA 8/1/05

LIKELY USERS: People wanting to support healthy blood flow to the brain and healthy neurological function 1-6,10 Those maintaining normal seasonal immune responses 7-10

KEY INGREDIENTS: 75 mg of Guaranteed Potency Butterbur Root (Petasites hybridus) Extract, min. 15 Sesquiterpenes as Petasines; 200 mg of Feverfew Leaf (Tanacetum parthenium) min. 0.4% Parthenolides

MAIN PRODUCT FEATURES: Butterbur (Petasites hybridus) is a native shrub of Europe, North America, and Asia that has been used by herbalists for centuries. Modern scientific studies have demonstrated that Butterbur supports healthy blood flow to the brain and healthy neurological function.1-6, 10 In addition, Butterbur may help to maintain balanced seasonal immune responses.7-10 In a synergistic base of guaranteed potency Feverfew leaf.11-26

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW Butterbur is free of harmful levels of Pyrrolizidine Alkaloids (PAs), the undesirable compounds naturally found in Butterbur, so it is safe to use regularly.

SERVING SIZE & HOW TO TAKE IT: Take one VCap one to three times per day, or as directed by your physician.

COMPLEMENTARY PRODUCTS: Magnesium, Ulcetrol, B-2, B-12, Fish Oil (EPA, DHA), SAM-e, Ginger, Ginkgo Biloba

CAUTIONS: None.

SPECIFIC: Do not discontinue use abruptly; taper off use if discontinuing. Discontinue use at least 14 days before surgery or oral surgery. Use with caution if you have ragweed allergies or blood disorders and let your physician know that you plan to use it before you take it. May be contraindicated for pregnant women.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

1. Diener HC, Rahlfs VW, Danesch U (2004) The First Placebo-Controlled Trial of a Special Butterbur Root Exract for the Preventio of Migraine: Reanalysis of Efficacy Criteria. Eur Neurol 51:89-97.
2. Lipton RB, Gobel H, Einhaupl KM, Wilks K, Mauskop A (2004) Petasites hybridus root (butterbur) is an effective preventative treatment for migraine. Neurology 63:2240-2244.
3. Pothmann R, Danesch U (2005) Migraine Preventiuon in Children and Adolescents: Results of an Open Study With a Special Butterbur Root Extract. Headache 45:196-203.
4. Rapaport AM, Bigal ME (2004) Perventive migraine therapy: what is new. Neurol Sci 25:S177-S185.
5. Wu SN, Chen H, Lin YL (2003) The mechanism of inhibitory actions of S-petasin, a sequiterpene of Petasites formosanus, on L-type calcium current in NG108-15 neuronal cells. Planta Med 69(2):118-124.
6. Wang G-J, Wu X-C, Lin Y-L, Ren J, Shum AY-C, Wu Y-Y, Chen C-F (2002) Ca2+ channel blockin effect of iso-S-petasin in rat aoritic smooth muscle cells. Eur J Pharmacol 445(3):239-45.
7. Lee DKC, Carstairs IJ, Haggart K, Jackson CM, Currie GP, Lipworth BJ (2003) Butterbur, a herbal remedy, attenuates adenosine monophosphate induced nasal responsiveness in seasonal allergic rhinitis. Clin Exp Allergy 33:882-886.
8. Lee DKC, Haggart K, Robb FM, Lipworth BJ (2004) Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids. Clin Exp Allergy 34:110-114.
9. Lee DKC, Gray RD, Robb FM, Fujihara S, Lipworth BJ (2004) A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis. Clin Exp Allergy 34:646-649.
10. (No Author) (2001) Petasites hybridus (Butterbur). Alt Med Rev 6(2):207-209.
11. Hayes NA, et al. The Activity of Compounds Extracted from Feverfew on Histamine Release from Rat Mast Cells. J Pharm Pharmacol. Jun1987;39(6):466-70.
12. 2 Groenewegen WA, et al. A ComParison of the Effects of an Extract of Feverfew and Parthenolide, a Component of Feverfew, on Human Platelet Activity In-vitro. J Pharm Pharmacol. 1990;42(8):553-57.
13 Capasso F. The Effect of An Aqueous Extract of Tanacetum parthenium L. on Arachidonic Acid Metabolism by Rat Peritoneal Leucocytes. J Pharm Pharmacol. Jan1986;38(1):71-72.
14. 4 Bejar E. Parthenolide Inhibits the Contractile Responses of Rat Stomach Fundus to Fenfluramine and Dextroamphetamine but not Serotonin. J Ethnopharmacol. Jan1996;50(1):1-12.
15. 5 Prusinski A, Durko A, Niczyporuk-Turek A. [Feverfew as a Prophylactic Treatment of Migraine]. Neurol Neurochir Pol. 1999;33(Suppl 5):89-95.
16. 6 Barsby RW, et al. Feverfew Extracts and Parthenolide Irreversibly Inhibit Vascular Responses of the Rabbit Aorta. J Pharm Pharmacol. Sep1992;44(9):737-40.
17. 7 Pittler MH, Vogler BK, Ernst E. Feverfew for Preventing Migraine (Cochrane Review). Cochrane Database Syst Rev. 2000;(3):CD002286.
18. 8 Pattrick M, et al. Feverfew in Rheumatoid Arthritis: A Double-blind, Placebo Controlled Study. Ann Rheum Dis. 1989;48:547-49.
19. 9 Makheja AM, et al. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostaglandin Leukotri Med. 1982;8:653-60. 20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada . Ottawa , Canada
20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada. Ottawa, Canada.
21. 14 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press; 1996:119-21.
22. 15 PDR for Herbal Medicines, 2nd ed. Montvale , NJ: Medical Economics Company; 2000:307.
23. 16 Pribitkin ED. Herbal therapy: what every facial plastic surgeon must know. Arch Facial Plast Surg. Apr2001;3(2): 127-32.
24. 17 Schmidt RJ. Plant dermatitis. Compasitae. Clin Dermatol. Apr1986;4(2):46-61.
25. 18 Heck AM, et al. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. Jul2000;57(13): 1221-7.
26. 19 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London : The Pharmaceutical Press; 1996:119-21.



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VitaBerry Plus+ Fact Sheet
TopPreviousNext

Date: December 07, 2005 05:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: VitaBerry Plus+ Fact Sheet

VitaBerry Plus+ Fact Sheet

Neil E. Levin, CCN, DANLA 3/18/05

LIKELY USERS: Antioxidant users who want the best food source formula; People seeking polyphenols or ellagic acid supplements; Those who don’t eat fruit and want some of their benefits

KEY INGREDIENTS: VitaBerry extract, Hi-Active Orange Extract, Pomegranate Extract (420 mg) (400 mg) (100 mg)

MAIN PRODUCT FEATURES: This is a high antioxidant (high ORAC: 2,500 units per serving of oxygen radical absorbing capacity), proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry extract, Grape & Grape seed extract, Raspberry & Raspberry seed extract, Cranberry, Prune, Tart Cherry, Wild Bilberry extract & Strawberry powder. Fortified with Hi-Active Orange Extract (Freeze-dried Orange (Citrus sinensis) powder with minimum of 40% vitamin C) and Pomegranate Extract (80% Polyphenols and 40% Ellagic Acid).

Provides a broad-spectrum antioxidant blend with phytochemicals such as anthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol etc. in a single “0” size vegetarian capsule. There is a synergistic effect of mixing fruit antioxidants that provides antioxidant protection greater than is predicted by measuring each fruit source used in the mix individually.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: There will be some natural variation in color, taste and odor from these fruit sources. A special freeze drying technique preserves the antioxidant value of whole fruits in a concentrated form.

SERVING SIZE & HOW TO TAKE IT: Serving is 2 Vcaps. Take one or more servings per day as an antioxidant supplement. May be taken with food or on an empty stomach (this is food).

COMPLEMENTARY PRODUCTS: All antioxidants.

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This information has not been reviewed by the FDA or the company posting it. Information given here may vary from what is given on the product label because this page represents my understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Bagchi D, Sen CK, Bagchi M, Atalay M. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Mosc). 2004 Jan;69(1):75-80, 1 p preceding 75. Review. PMID: 14972022

Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 2002 Jul 15;22(14):6114-20. PMID: 12122072

Huang D, Ou B, Prior RL. The Chemistry behind Antioxidant Capacity Assays. J Agric Food Chem. 2005 Mar 23;53(6):1841-1856. PMID: 15769103

Kay CD, Holub BJ. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 2002 Oct;88(4):389-98. PMID: 12323088

Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 2002 Dec 18;50(26):7731-7. PMID: 12475297

Prior RL, Cao G. Analysis of botanicals and dietary supplements for antioxidant capacity: a review. J AOAC Int. 2000 Jul-Aug;83(4):950-6. Review. PMID: 10995120

Prior RL, Cao G. In vivo total antioxidant capacity: comParison of different analytical methods. Free Radic Biol Med. 1999 Dec;27(11-12):1173-81. Review. PMID: 10641708

Prior RL, Hoang H, Gu L, Wu X, Bacchiocca M, Howard L, Hampsch-Woodill M, Huang D, Ou B, Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples. J Agric Food Chem. 2003 May 21;51(11):3273-9. PMID: 12744654

Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Radic Res. 2002 Feb;36(2):217-33. PMID: 11999391

Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berries. Free Radic Res. 2002 Sep;36(9):1023-31. PMID: 12448828

Sofic E, Rustembegovic A, Kroyer G, Cao G. Serum antioxidant capacity in neurological, psychiatric, renal diseases and cardiomyopathy. J Neural Transm. 2002 May;109(5-6):711-9. PMID: 12111462

Stintzing FC, Stintzing AS, Carle R, Frei B, Wrolstad RE. Color and antioxidant properties of cyanidin-based anthocyanin pigments. J Agric Food Chem. 2002 Oct 9;50(21):6172-81. PMID: 12358498

Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37. PMID: 15186133

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Utah's Inland Sea Minerals – Topical Application
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Date: November 22, 2005 09:23 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Utah's Inland Sea Minerals – Topical Application

Minerals provide a bounty of healing properties that have scientifically validated their use for topical applications. These applications have been shown to have powerful local and systemic effects. The health of ones skin and hair reflects inner health. Indeed, we judge the health of animals and humans alike by their outward appearance of fur or skin, respectively. The human skin is the largest organ of the body and is highly involved in the detoxification and maintenance processes of health. Skin not only excretes and eliminates toxins; it also has a tremendous capacity to absorb health supportive substances. The pharmaceutical industry frequently takes advantage of the skin’s absorptive capacity with drug therapies. Such therapies include the transdermal delivery of drugs like nicotine, hormone patches, progesterone creams and so forth. Thus, it is apparent that natural therapies can have pronounced and powerful health effects.

Clinical researchers have continued to document the clinical findings that have been observed for decades when it comes to the healing properties of topical minerals. Many of the studies on therapeutic baths have used minerals from the Dead Sea, an ancient inland sea. However, a similar and impressive array of minerals occurs in the other inland sea, the Great Salt Lake. Indeed, the high presence of magnesium from both inland seas appears to be the foremost active mineral. A comParison chart below clearly reflects the mineral analysis and similarity (see chart below). The following survey of medical research reflects a few of the many therapeutic roles for mineral salt baths. Of particular interest are the powerful effects of magnesium salts that are prevalent to both Utah’s Inland Sea and the Dead Sea that exhibit favorable effects in inflammatory disease. Arthritis:

103 patients with arthritic symptoms were treated for 1-2 weeks. They received various bath treatments with the ionic trace minerals. The study showed that the higher concentration baths offered the most impressive results. Those with the greatest physical limitation had the most pronounced improvement. Over 80 percent of the patients reported having less pain, 70 percent reported improved mobility and 60 percent were able to decrease analgesic use (i). In a different double-blind study, the use of warm mineral baths with Dead Sea salt demonstrated a lasting effect for patients suffering from degenerative arthritis. (ii)

Skin:

In a clinical trial conducted by a leading research university in Germany, patients with atopic (eczema) skin disorders immersed their arms in a magnesium chloride rich bath. The participants immersed one arm in tap water the other in the therapeutic magnesium rich bath. The findings showed that skin hydration was improved and skin roughness and inflammation was reduced. The researchers stated “magnesium salts are known to bind water, influence epidermal proliferation and differentiation and enhance barrier repair.” (iii) Another study showed that magnesium salts when exposed to both psoriatic and healthy skin cells provided an important anti-proliferative effect (iv). Yet another study showed that the effects of mineral baths from the Dead Sea had lasting effects for upwards of a month after treatment. (v) Head to Head ComParison (vi) (vii)

Utah’s Inland Sea Composition Dead Sea Composition
Magnesium Chloride 1.04% 4.03%
Potassium Chloride 0.64% 0.72%
Sodium Chloride 9% 3.87%
Calcium Chloride 0.08% 1.64%
Chloride 15.12% 21.11%
Sulfates (SO4) 2.13% 0.03%

By: Dr. Chris Meletis N. D.

References:
• (i) Dead Sea Balneoptherapy is Osteoarthritis, Dr. Machety (Hasharon Hospital, Petach-Tikva, Israel). Published in Proceedings of International Seminar on Treatment of Rheumatic Diseases. John Wright-PSG ,1932.
• (ii) Sukenik S, Mayo A, Neumann L et al., Dead Sea bath salts for osteoarthritis of the knee, Harefuah 1995; 129(3-4):100-3, 159, 158.
• (iii) Proksch E, Nissen HP et al., Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. Int J Dermatol 2005; 44(2):151-7.
• (iv) Levi-Schaffer F, Shani J, Politi Y et al., Inhibition of proliferation of psoriatic and healthy fibroblasts in cell culture by selected Dead –sea salts. Pharmacology 1996; 52(5):321-8.
• (v) Sukenik S, Neumann L, Buskila D et al., Dead Sea bath salts for the treatment of rheumatoid arthritis. Clin Exp Rheumatol 1990; 8(4):353-7.
• (vi) The Utah Department of Natural Resources, Utah Geological and Mineral Survey Public Information Series #8, 1990.
• (vii) Gwynn, J. Wallace, The Utah Department of Natural Resources, Utah Geological Public Information Series 51, 1997.

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Research on SAMe....
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Date: October 26, 2005 12:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Research on SAMe....

Two groups of researchers have conducted analyses of trials that utilized SAM-e for mood enhancement. One meta-analysis was published in 1994. The researchers analyzed the efficacy of SAM-e in oral or injection forms based on published trials dated between 1973 and 1992. The authors concluded that there was a significant improvement of 17 to 38% seen in trials of SAM-e compared to placebo response. They state that the efficacy of SAM-e was superior to placebo and its administration caused few side effects.5 A second review was published in 2002. The authors analyzed studies in which SAM-e doses ranged from 200 to 1600 mg daily. They also found a significant effect of SAM-e in comParison to placebo, with an evident rapid onset of effect at enhancing mood.6

Promotes Joint Comfort and Mobility*

As a sulfur donor to connective tissue, SAM-e plays a major role in protecting the integrity of cartilage tissue. An in vitro trial assessed the actions of SAM-e in cultured human articular chondrocytes. At a concentration of 10 micrograms/ml, proteoglycan synthesis and sulfate residue incorporation in chondrocytes was shown to be 60% higher than control levels. Based on these results, it was shown that SAM-e has a positive influence on the growth and health of cartilaginous connective tissue.7

In a double-blind trial with 734 individuals with compromised joint health. SAM-e given orally at a dose of 1200 mg daily for 30 days was shown to significantly promote joint comfort compared to placebo, with a high level of tolerability and low incidence of side effects. The researchers concluded that SAM-e is a highly effective supplement for enhancing joint comfort.8

Another trial evaluated the response of individuals experiencing discomfort in the joints to a regimen of 1200 mg SAM-e for 1 week followed by 800 mg for the second week, and then 400 mg for weeks 3 through 8. This open trial of 20, 641 people showed a strong ability of SAM-e to enhance feelings of comfort within the joints. The treatment was rated as “very good” or “good” in 71% of the participants, with an additional 21% rating the treatment effect as “moderate”.9

In a long-term trial lasting 24 months, SAM-e was given to 108 participants with compromised joint function. Individuals were given 600 mg orally per day for the first two weeks followed by 400 mg daily for the remainder of the trial. Individuals experienced significant enhancements in joint comfort, with dramatic improvements noted after 2-4 weeks of treatment. Improvements continued to 6 months and beyond.10

In addition to the above studies, a review was conducted in 1987 to assess the results of SAM-e supplementation in clinical trials for enhancing joint mobility and function. Over 22,000 individuals had participated in the clinical trials that were the subject of this review. The author concluded from his analysis that SAM-e was shown to be highly efficacious, rivaling or surpassing the effectiveness of other treatments, and also possessing a high level of safety.11 Because of this, SAM-e may be the treatment of choice for enhancing joint function.

Supports Liver Health and Detoxification*

SAM-e supplementation can have profound benefits on liver function. These benefits center around its function as the major methyl donor in the liver, as well as its lipotropic activity. SAM-e also enhances the production of the antioxidant glutathione.

A number of trials have been conducted showing the ability of SAM-e to support liver detoxification functions and enhance liver health in individuals susceptible to toxin-induced liver compromise. SAM-e has the ability to normalize liver function by increasing the activity of enzymes needed to upregulate liver detoxification. These effects are comprehensive and rapid. Dosages used in these studies range from 600 mg to 1600 mg daily for 2 months to two years.12,13,14 In these trials, significant benefits of SAM-e supplementation were seen over placebo.

Safety

SAM-e has an excellent safety profile and is considered well-suited for long term use based on multiple clinical trials. Individuals diagnosed with manic depression should avoid SAM-e supplementation, as it may aggravate the manic phase *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1. Agnoli A, Andreoli V, Casacchia M, Cerbo R. Effect of s-adenosyl-l-methionine (SAMe) upon depressive symptoms. J Psychiatr Res. 1976;13(1):43-54.

2. De Leo D. S-adenosylmethionine as an antidepressant. Curr Ther Research. 1987;41(6):865-70.

3. Kagan BL, Sultzer DL, Rosenlicht N,Gerner RH. Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 1990 May;147(5):591-5.

4.Salmaggi P,Bressa GM,Nicchia G,Coniglio M,La Greca P,Le Grazie C.Doubleblind, placebo-controlled study of S-adenosyl-L-methionine in depressed postmenopausal women. Psychother Psychosom. 1993;59(1):34-40.

5. Bressa GM. S-adenosyl-l-methionine (SAMe) as antidepressant: metaanalysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. 6.Mischoulon D, Fava M. Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr. 2002 Nov;76(5):1158S-61S.

7. Harmand MF, Vilamitjana J,Maloche E, Duphil R, Ducassou D. Effects of Sadenosylmethionine on human articular chondrocyte differentiation. An in vitro study. Am J Med. 1987 Nov 20;83(5A):48-54.

8. Caruso I, . Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease. Am J Med. 1987 Nov 20;83(5A):66-71.

9. Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. Report of an open phase IV study with ademetionine (Gumbaral). Am J Med. 1987 Nov 20;83(5A):84-8.

10. Konig B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med. 1987 Nov 20;83(5A):89-94.

11. di Padova C. S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. Am J Med. 1987 Nov 20;83(5A):60-5.

12. Frezza M, et al. S-adenosylmethionine counteracts oral contraceptive hepatotoxicity in women. Am J Med Sci. 1987; 293(4):234-238.

13. Frezza M, Surrenti C, Manzillo G, Fiaccadori F, Bortolini M, Di Padova C. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Gastroenterology. 1990 Jul;99(1):211-5.

14. Mato JM, et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol. 1999 Jun;30(6):1081-9.



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Comprehensive Prostate Formula-the Clinical Studies
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Date: October 13, 2005 04:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Comprehensive Prostate Formula-the Clinical Studies

Helps maintain a healthy prostate gland.

Supports normal urinary function.

Comprehensive Prostate Formula-the Clinical Studies

Saw palmetto Extract

Saw palmetto extract is one of the world's leading herbal products for prostate support. Widely-cited clinical studies conducted over the last fifteen years suggest Saw palmetto extract can produce major improvements in prostate-related urinary function. In clinical studies, Saw palmetto extract has produced measurable improvements in urinary functions and prostate size. Quality of life scores have also improved. The results with Saw palmetto extract have been duplicated in open trials and controlled, double-blind studies.11,12,13 For example, in a large open trial, 505 men took 320 mg of Saw palmetto extract daily for three months.1 The results were evaluated with various measurements such as the International Prostate Symptom Score, the quality of life score, urinary flow rates, residual urinary volume, and prostate size. After 45 days these parameters improved significantly. After 90 days of treatment nearly ninety percent of both the doctors and patients regarded Saw palmetto extract as effective as therapy for the prostate.

The changes in prostate health that accompany middle age are related to the hormone DHT, or dihydrotestosterone, a metabolite of testosterone. DHT levels rise, and DHT binds to prostate cells, accelerating growth of prostate tissue. Saw palmetto extract has been shown to inhibit 5 alpha-reductase, an enzyme that controls conversion of testosterone to DHT.14 Experimental evidence suggests Saw palmetto extract blocks the binding of DHT to prostate cells.15 The fatty acids and sterols in Saw palmetto are believed to be responsible for these actions.14,16 These include oleic acid, lauric acid, campasterol, stigmasterol, beta-sitosterol and others. Clinical studies have used extracts containing 85 to 90 percent fatty acids and sterols.

Pygeum Extract

Like Saw palmetto, Pygeum contains natural sterols and fatty acids.2 Although the mechanisms for its effect have not been clearly established, animal experiments suggest Pygeum may work by inhibiting prostate cell proliferation and reducing inflammation.17,18 In several European trials, Pygeum has successfully improved urinary function. In a large double-blind, placebo-controlled study, 263 men were given 100 mg of Pygeum extract a day for 60 days. Urination improved in 66 percent of the men taking Pygeum, compared with 31 percent on placebo, based on subjective and objective tests.19

Nettle Root Extract

Nettles are approved by the German Commission E as effective for relieving inflammation in the urinary tract.20 As far back as 1950, German investigators have observed favorable effects on the prostate with the use of Nettle root. These initial findings have been confirmed through case studies, as well as double-blind studies, published mainly in German medical journals. In a recent double blind study published in the journal Clinical Therapeutics, 134 men took a combination of Nettle root extract and Pygeum extract over a period of 56 days.3 Urination was significantly improved.

L-Alanine, Glutamic Acid and Glycine

As noted above, Drs. Feinblatt and Gant discovered that a combination of the amino acids L-alanine, glutamic acid and glycine has a positive effect on prostate-related urinary function.5 A controlled study of 45 men was conducted to follow up on these initial observations.21 The majority of subjects experienced complete or partial relief in urinary complaints such as nighttime urination and urgency.

Scientific References
1. Braeckman, J., 'The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study,' Current Therapeutic Research 1994: 55(7):776-85.

2. Lawrence Review of Natural Products. Pygeum. Jan 1998. Facts and ComParisons, St. Louis, MO.

3. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comParison of two doses Clinical Therapeutics 1993; 15(6):1011-19.

4. Wagner, H., Willer, F., Samtleben, R., Boos, G. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots Phytomedicine 1994; 1:213-224.

5. Feinblatt, H.M., Gant, J.D. Palliative treatment of benign prostatic hypertrophy. Journal of the Maine Medical Association, March 1958:99-124.

6. Giovanni, E., et. al. Intake of carotenoids and retinol in relation to risk of prostate cancer. Journal of the National Cancer Institute 1995;87(23):1767-76.

7. Wallace, A.M., Grant, J.K. Effect of zinc on androgen metabolism in the human hyperplastic prostate. Biochemical Society Transactions 1975; 3(3):540-42

8. Badmaev, V., Majeed, M., Passwater, R. Selenium: A quest for better understanding. Alternative Therapies 1996; 2(4):59-67.

9. Fouhad, M.T. Selenium and cancer, chromium and diabetes: two trace elements that have merits as dietary supplements in human nutrition. Journal of Applied Nutrition 1979:31(1&2):14-17.

10. Vescovi, P.P., et. al. Pyridoxine (Vit. B6) decreases opoids-induced hyperprolactinemia. Horm. metabol. Res. 1985; 17:46-47.

11. Tasca, A., et. al. Treatment of obstructive symptomatology caused by prostatic adenoma with an extract of Serenoa repens. Double-blind clinical study vs. placebo. Minerva Urologica e Nefrologica 1985; 37:87-91.

12. Champault, G., Bonnard, A.M., Cauquil, J., Patel, J.C. Medical treatment of prostatic adenoma. A controlled test of PA 109 vs. placebo in 110 patients. Ann. Urol. 1984; 18(6):407-410.

13. Crimi, A., Russo, A. The use of Serenoa repens extract in the treatment of functional disturbances caused by prostate hypertrophy. Med. Praxis 1983; 4:47-51.

14. NiederprŸm, H.J., Schweikert. H.U., ZŠnker, K.S. Testosterone 5 alpha-reductase inhibition by free fatty acids from Sabal serrulata fruits. Phytomedicine 1994; 1:127-133.

15. Sultan, C., et. al. Inhibition of androgen metabolism and binding of liposterolic extract of Serenoa repens B in human foreskin fibroblasts. J. Steroid Biochem. 1984; 20(1):515-519.

16. Weissner, H., et. al. Effects of the Sabal serrulata extract IDS 9 and its subfractions on 5 alpha-reductase activity in human benign prostatic hyperplasia. The Prostate 1996;28:300-06.

17. Yablonsky, F. Nicolas, V., Riffaud, J.P., Bellamy, F. Antiproliferative effect of Pygeum africanum on rat prostatic fibroblasts. J. of Urology 1997; 157:2381-87.

18. Marconi, M. et. al. Anti-inflammatory action of Pygeum extract in the rat. Farmaci. & Terapia. 1986; 3:135.

19. Barlet, A, et. al. Efficacy of Pygeum africanum extract in the treatment of micturational disorders due to benign prostatic hyperplasia. Evaluation of objective and subjective parameters. A multicenter, randomized, double-blind trial. Wien. Klin. Wocheschr. 1990; 22:667-73.

20. The Complete German Commission E Monographs. 1998, Blumenthal, M., ed., (p.216) Austin, TX: American Botanical Council.

21. Damrau, F. Benign prostatic hypertrophy: amino acid therapy for symptomatic relief. American Journal of Geriatrics 1962; 10:426-30.



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Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of...
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Date: July 27, 2005 12:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of...

Benefits

• Supports Healthy Joint Structure and Function*

Components of BioCell Collagen II including collagen type II, chondroitin sulfate and hyaluronic acid (HA) can enhance proteoglycans in the joint matrix, thereby providing support for healthy joint function and maintaining joint shock absorption and cushioning.

CHONDROITIN SULFATE

Chondroitin has been well studied for its effects on joint health. In a 1996 controlled, double-blind trial published in the Journal of Rheumatology, 146 volunteers consumed chondroitin sulfate daily for 6 months. Changes in joint function were measured according to several clinical parameters and carefully analyzed. After the first month, significant improvements were noted and maintained for three months after the subjects stopped taking the chondroitin sulfate.1 In an earlier double-blind study subjects taking chondroitin sulfate had improvements in joint function after three months of use, as determined by both objective and subjective measurements.2 In both studies, the benefits lasted for weeks after subjects stopped taking chondroitin sulfate.

In another controlled study, 192 subjects took chondroitin sulfate or a placebo daily for one year. At the end of the trial, chondroitin sulfate maintained healthy joint cartilage thickness, while those on placebo had decreased cartilage. Improvements in joint function also occurred. The researchers reported that chondroitin exerted a clear chondroprotective effect.3

COLLAGEN TYPE II

A number of studies have also been conducted on the administration of collagen type II to individuals that have various joint issues. Much of this research has been conducted on animal models of joint conditions while there are also studies showing the effectiveness of oral collagen type II preparations in humans for maintenance of healthy joints.

A randomized controlled trial conducted on 60 patients with joint health issues in 1993 found that oral administration of chicken collagen type II for 3 months led to a significant decrease in swollen and tender joints in this group, as compared to no measurable improvement in the placebo group. There were also no side effects seen with the treatment.4 A second multicenter, double-blind, placebo-controlled trial in 274 individuals with joint issues was published in 1998. The participants were given collagen type II orally for 24 weeks. Positive effects of the treatment were noted while no adverse effects were seen.5

A paper published in 2000 reviewed the literature to assess the role of hydrolyzed collagen in joint and bone health. It was found that hydrolyzed collagen when administered orally was able to support joint health in most of the trials reviewed while the author concluded that, “Its high level of safety makes it attractive as an agent for long-term use.”6

HYALURONIC ACID (HA)

Most of the literature on hyaluronic acid and joint health deals with its intra-articular use, or injections of HA directly into the joints. In this realm, there is good evidence for the effects of HA on joint function.

A study was conducted with injectable HA in individuals with TMJ (temporomandibular joint) conditions. Participants received two injections, each one week apart, or placebo injections with saline. In the HA group, the researchers found decreased clicking sounds and increased function of the joint at 1 month (90% of patients showed improvement) and 6 months (63%) of follow-up, compared to about 26% of the placebo group showing improvement at 6 months.7

A pair of researchers also conducted a literature review of the trials using HA for improving joint health that was published in 2005. Their findings indicate a positive role for HA in modifying the structure of the joint and slowing progressive deterioration of joint function and mobility.8 Hyaluronic acid seems to have a natural affinity for joint tissue, and is therefore able to help support healthy joint structure and function.

• SuSupports Healthy Joint Structure and Function*

Hyaluronic Acid and Collagen are both vital components of skin tissue. Both compounds are known to decline with aging. Collagen is a vital structural component of the skin. It is also one of the most important substances required for proper skin barrier function and health. Collagen, as a major component of the connective tissue, provides structural support, increasing elasticity and tone of the skin.

In 1994, researchers performed comparative measurements of hyaluronic acid levels in the skin of young and elderly individuals. The researchers had hypothesized that a major reason for the aged appearance of skin in the elderly is a reduction of hyaluronic acid levels. What they found using their methods is that there is a progressive reduction in the number of hyaluronic acid granules in human skin with age, until a complete absence of these granules was seen in individuals 60 years or older. These variations in HA levels with age could, according to the researchers, account for the decreased turgidity, wrinkled appearance and altered elasticity of skin tissue.9 Further research was needed to determine the effect of exogenously administered HA on the suppleness of human skin.

In a laboratory study conducted in 1998, researchers analyzed the effects of HA given to live human skin cells. Whereas the cells on their own had a low rate of renewal, hyaluronic acid added to the cells resulted in increased proliferation of skin cells in the collagen matrix. This showed that supplementing skin cells with HA caused a significant increase in the ability of cells to go through the cell cycle.10 One of the major benefits of this may be hyaluronic acid’s ability to continually renew skin tissue to help maintain a youthful appearance of the skin.

Safety

Suggested Adult Use: Take 2 capsules daily, or as directed by a health care practitioner. Take with 8-10 ounces of water, with or without food.

Scientific References

1. Morreale P, et al. ComParison of the antiinflammatory efficacy of chondroitin sulfate and diclofenac sodium in patients with knee osteoarthritis. J Rheumatol (1996) 23:1385-91.

2. Mazières B, et al. Chondroitin sulfate for the treatment of coxarthrosis and gonarthrosis. A prospective, multicenter, placebo-controlled, double blind trial with five months follow up. Rev. Rhum. Mal. Ostèoartic. 1992;59(7-8):466-472.

3. Pipitone V, et al. A multicenter, triple-blind study to evaluate galactosaminoglucuronoglycan sulfate versus placebo in patients with femorotibial gonarthritis. Current Therapeutic Research 1992 52(4):608-38.

4. Trentham DE, et al. Effects of oral administration of type II collagen on rheumatoid arthritis. Science. 1993 Sep 24; 261(5129) 1727-30.

5. Barnett ML, et al. Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum. 1998 Feb; 41(2): 290-7.

6. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease. Semin Arthritis Rheum. 2000 Oct;30(2):87-99.

7. Hepguler S, et al. The efficacy of intra-articular sodium hyaluronate in patients with reducing displaced disc of the temporomandibular joint. J Oral Rehab. 2002; 29: 80-86.

8. Goldberg VM, Buckwalter JA. Hyaluronans in the treatment of osteoarthritis of the knee: evidence for disease-modifying activity. Osteoarthritis Cartilage. 2005 Mar;13(3):216-24.

9. Ghersetich I, et al. Hyaluronic acid in cutaneous intrinsic aging. Int J Dermatol. 1994 Feb; 33(2): 119-22.

10. Greco RM, et al. Hyaluronic acid stimulates human fibroblast proliferation within a collagen matrix. J Cell Physiol. 1998 Dec; 177(3): 465-73.

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Best Mangosteen 10% Extract with xanthone flavonoids
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Date: July 27, 2005 11:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Best Mangosteen 10% Extract with xanthone flavonoids

Benefits

• Defends Against Free Radicals*

The xanthone flavonoids and other compounds in mangosteen fruit are responsible for its high level of antioxidant activity. In vitro tests have been conducted on XanoMax? mangosteen 10% extract to determine the level of free radical scavenging ability in both watery and fatty environments. A major test recognized as the industry standard for measuring antioxidant activity is known as the ORAC (Oxygen Radical Absorbance Capacity) assay.

The ORAC test is an in vitro assay that works by measuring the amount of free radical damage done to a fluorescent probe (measured by a change in probe intensity). Antioxidants lessen the damage to the probe fluorescence, which indicates a reduction in free radical damage. This measure is used to quantify the antioxidant’s (or combination of antioxidants) capacity to quench free radicals. This quantification is known as the total ORAC value. The total ORAC value provides a relative measure of total antioxidant strength of any substance, allowing for comParison of different mixtures. A high ORAC value corresponds to a high total in vitro antioxidant capacity.

The development of the ORAC test has led to a number of commonly eaten foods being assessed in terms of total ORAC scores per serving. Similarly, particular combinations of antioxidants, such as those in nutritional formulas, can also be assessed for their total ORAC scores. This has led to the ability to determine the potential usefulness of a particular supplement in increasing overall antioxidant capacity.

When XanoMax? mangosteen 10% extract was tested for ORAC value, the resulting antioxidant potential was over 3,500 ORAC units per gram of extract. This result is extremely high. ORAC values of compounds vary with their nutrient concentration, moisture content and other factors. For comParison purposes, whole blueberries, considered to be a rich source of antioxidants, had an ORAC value of 61 units per gram, while pomegranate tested at 105 ORAC units per gram.1 XanoMax? mangosteen extract is a potentially rich source of beneficial antioxidants*

• Maintains Healthy Immune Function*

Evidence from several animal and in vitro studies on various cell lines suggests that components of mangosteen fruit extract may play a role in modulating several factors important to healthy immune function. Of the active components, xanthone derivatives seem to play the major role in influencing parameters of immune function in animals and in vitro models. Mangostin is the xanthone derivative that most of these studies have focused on.

A study published in 2002 assessed the effects of mangosteen extracts on the release of histamine from rat cell lines. The comParison was made to extracts of a plant frequently used in Japan, Rubus suavissimus, which is a known inhibitor of IgE-mediated histamine release from these cells. The assay showed that the mangosteen extracts used inhibited the release of histamine from these cells more potently than the extract of Rubus suavissimus. In addition, the authors compared the two herbs for prostaglandin E2 synthesis in another rat cell line and found that the mangosteen extract potently inhibited prostaglandin E2 synthesis in this in vitro trial, whereas the other herb had no effect.2

An earlier study was performed in guinea pig tracheal and rabbit thoracic aortal tissue. In this study, alpha mangostin prevented histamine-induced contraction and was shown to be a competitive histamine receptor antagonist in the smooth muscle tissue of the trachea and aorta of the animals selected. The results seen in this laboratory study were determined to be concentration-dependent. The authors suggested that alpha mangostin should undergo further studies to determine its effects on the modulation of the histamine response.3

Further in vitro assessments point to potential actions of mangosteen components in modulating effectors of occasional inflammation in the immune system. Studies in rat glioma cells suggest that mangostins inhibit enzymatic reactions that can lead to the production of specific prostaglandins.4,5 By inhibiting these reactions, mangostins may play a role in modulating overall immune function, promoting healthy immunity.

Mangosteen and its constituents hold much promise for their potential ability to enhance immune function and promote health. In addition to being a highly nutritious food, mangosteen extract is full of antioxidant activity. It has an extremely high ORAC value and a great potential for enhancing free radical defenses in the body. Best Mangosteen 10% extract contains XanoMax ™, which is standardized to a high level of active mangostin, the class of compounds shown in in vitro studies to benefit certain aspects of immune function. Safety Scientific References

1. XanoMax ™: High-potency extract of Mangosteen, Garcinia mangostana. Renaissance Herbs. From www.renaissanceherbs.com
2. Nakatani K, et al. Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull. 2002 Sep;25(9):1137-41.
3. Chairungsrilerd N, et al. Pharmacological properties of alpha-mangostin, a novel histamine H1 receptor antagonist. Eur J Pharmacol. 1996 Oct 31;314(3):351-6.
4. Nakatani K, et al. Gamma-Mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells. Mol Pharmacol. 2004 Sep;66(3):667-74.
5. Nakatani K, et al. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002 Jan 1;63(1):73-9.

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SIDE EFFECTS OF SYNTHETIC PROGESTIN DRUGS
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Date: July 25, 2005 09:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: SIDE EFFECTS OF SYNTHETIC PROGESTIN DRUGS

SIDE EFFECTS OF SYNTHETIC PROGESTIN DRUGS

Premarin and Provera are two of the most commonly prescribed progestin drugs and come with a wide variety of side effects and health risks. Over 30 negative side effects are listed for Provera alone. Taking Provera during early pregnancy may actually cause a miscarriage or deformity of the developing fetus. Premarin is comprised of two different types of estrogen called estrone and estradiol, which have been linked with the development of certain kinds of cancer.

The risks involved with taking these synthetic progestins is due to their chemical structures. For the most part, the compound resembles natural progesterone, therefore it binds to the same receptor sites as to natural progesterone. The altered portions of the molecule, however, convey a totally different signal to the cells involved. It is this atomic manipulation which poses alarming health risks to the body. Health risks which are not associated with natural hormonal precursors. A few of the side effects associated with synthetic progestins include:

  • • increased risk of cancer
  • • fluid retention
  • • migraines
  • • kidney problems
  • • breast tenderness
  • • blood clots
  • • changes in cholesterol levels
  • • menstrual irregularities
  • • blood sugar disorders
  • • weight gain
  • • high blood pressure
  • • depression
  • • birth defects
  • • miscarriage

    As is often the case, eventually the perils of synthetically derived plant analogues made health practitioners question their usage and the notion of using progesterone in its natural state has re-emerged. Unfortunately, its classification as a non-patentable simple substance relegates it to the status of an herbal supplement, which most doctors will not endorse. Synthetic drugs are more potent, usually easier to take, have a longer physiologic action and are patentable. For all of these reasons, natural phytomedicines have been shelved as relatively worthless in comParison. Chemically altered progesterone is considered technically superior when in reality, natural forms of progesterone may often be preferable.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=660)


    References
    TopPreviousNext

    Date: July 13, 2005 12:42 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: References

    ENDNOTES


    1 Time Magazine, (April 6, 1992).
    2 Indena Fact Sheet, # 16.
    3 The New York Times. (April 25, 1993).
    4 Jon J. Mich n ovicz, M.D., Ph.D. H ow to Reduce Your Risk of Breast Cancer, (New York: Warner Books, 1994), 103.
    5 Richard A. Passwater Ph.D., Cancer Prevention and Nutritional T h e ra p i e s, (New Canaan, Connecticut: Keats Publishing, 1993).
    6 G. Block, University of Southern California at Berkeley
    7 “ L e u c o a n t h o c yanins Extract From Grapeseeds (Vins Vinifera),” Indena Publication
    8 Liviero, International Symposium on Phytochemistry of Plants Used in Traditional Medicine.
    9 R.I. Rayer, and C. L. Schmidt, Seminary Hospital, (Paris: 1981), 57, 2009 and Indena International Report (Data on File). 10 J . F. Thebaut, P. Thebaut and F. Vin, Gazet te Medicale, (1985), 92, 96.
    11 L. Fusi, F. Czimeg, F. Pesce, R. Germagli, A. Boero, M. Vanzetti, G. Gandiglio, Ann Ott Clin, Ocul, (1988) 114, 575.
    12 D. Zafirov, G. Bredy-Dobreva, V. Litchev, M. Papasovasvie, Ac ta Physiol Pharmacol, Inst i t u te of Phys i o l o g y, Bulgarian Academy of Sciences, (Sofia, Bulgaria: 1990) 16 (3) 50-54.
    13 B. Vennet, “Anti-ulcer Activity of Procyanidin Preparation of Wa ter Soluble Pro c yanidin Cimetidine Comp l exes,” Pharm Acta Helv, (Switzerland: 1989), 64 (11) 316-20
    14 “Leucoanthocyanins Extract From Grapeseed (Vins Vinfera)” Indena Publication.



    --
    Vitanet ®

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    PYCNOGENOL - ITS REMARKABLE BENEFITS
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    Date: July 13, 2005 12:26 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: PYCNOGENOL - ITS REMARKABLE BENEFITS

    PYCNOGENOL - ITS REMARKABLE BENEFITS

    New to North America but not to Europe, this natural product is considered safe and effective in the treatment of various diseases and for the maintenance of optimal health. This family of bioflavonoids is non-toxic, water soluble and highly bioavailable. Because proanthocyanidins scavenge free radicals so effectively, they have shown remarkable curative effects. Extensive research demonst rates that proanthocyanidins are such potent antioxidants, they find and neutralize free radicals with great rapidity, allowing cells to regenerate rather than deteriorate. Specific actions associated with Pycnogenol include:

  • • Binds with Collagen Fibers and helps restore skin elasticity
  • • Helps prevent excess wrinkling
  • • Protects capillaries from free radical damage which helps prevent phlebitis, varicose veins and bruising
  • • Treats Joint Pain and Injuries as a natural antiinflammatory
  • • Helps control and prevent edema
  • • Decreases the production of histamines in allergic reactions such as Hay Fever
  • • Reduces the risk of and treats diabetic retinopathy

    PYCNOGENOL SPECIFICALLY TARGETS: SKIN AND ELASTICITY

    Testing has suggested that Pycnogenol flavonoids exhibited an anti-enzyme effect which prevented the break down of collagen and elastin, the very compounds which keep skin firm and inhibit the formation of wrinkles.7

    TUMOR RELATED DISEASES

    Unquestionably, studies have shown that Pycnogenol has the ability to inhibit cellular mutations.8 The implications of this finding for anyone suffering from tumor related disease which originates from cellular malfunctions should not be underestimated.

    CARDIOVASCULAR CONDITIONS

    The potential of Pycnogenol to pr e vent cellular deterioration or uncontrolled growth is profound to say the least. Several investigations have shown that if it is taken on a daily basis, Pycnogenol benefits people suffering from cardiovascular diseases and breast tumors.9 In addition, double blind placebo controlled studies have indicated that patients suffering from circulatory insufficiencies and diseases of the lymph system showed significant improvement in pain control and vessel elasticity after taking these flavonoids.10

    VISION

    Subsequent experiments concluded that the family of bioflavonoids contained in Pycnogenol is capable of improving night vision and initialing “a rapid and marked improvement of visual performances after glare in comParison with control group.”11

    WATER RETENTION AND EDEMA

    Pycnogenol is particularly valuable for anyone who suffers from water retention and edema. Studies at the Institute of Physiology at the Bulgarian Academy of Sciences confirm that this biofl avonoid compound stabilized capillary walls, which decreased fluid leakage into tissues which causes swelling and pressure.12

    WHAT PATHOLOGICAL CONDITIONS RESPOND TO PYCNOGENOL?

    The bioflavonoids found in Pycnogenol have been clinically indicated in the following pathological conditions:

  • • circulatory diseases, including cardiovascular disease and stroke
  • • varicose veins
  • • edema
  • • bruising
  • • capillary fragility (commonly seen in diabetes can cause retina damage and decrease sight)
  • • visual disturbances
  • • aging of skin
  • • diabetes
  • • stroke
  • • prostate disease
  • • wrinkles
  • • stress

    PYCNOGENOL HAS THERAPEUTIC VALUE FOR THE FOLLOWING CONDITIONS:

  • • BELL’S PALSY
  • • ULCERS
  • • EYESIGHT: INCREASES VISUAL ACUITY
  • • CANCERS: INHIBITS TUMOR GROWTH
  • • HEART DISEASE
  • • ATHEROSCLEROSIS
  • • MULTIPLE SCLEROSIS
  • • COLDS AND FLU
  • • PROSTRATE PROBLEMS
  • • LUPUS
  • • ARTHRITIS
  • • MEMORY/ALZHEIMER’S DISEASE, SENILE DEMENTIA
  • • STROKE
  • • PARKINSON’S DISEASE
  • • PSORIASIS
  • • BURSITIS
  • • GASTROINTESTINAL PROBLEMS
  • • INSOMNIA
  • • IT CAN ALSO HELP TO INCREASE LONGEVITY AND OVERALL HEALTH

    PYCNOGENOL CAN CROSS THE BLOOD-BRAIN BARRIER

    One of the most significant advantages of this flavonoid compound is its ability to cross the blood-brain barrier. Consequently, it acts as an invaluable therapeutic agent in treating depression, chronic fatigue, insomnia or loss of memory.

    ANTI-ULCER FORMING PROPERTIES

    Other scientific tests have indicated that proanthocyanidins also posses anti-ulcer properties and may work to prevent the formation of undesirable chemicals in the stomach.13

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=608)


    Pain - Post Op and Relaxation
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    Date: July 13, 2005 09:24 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Pain - Post Op and Relaxation

    Relaxation, Music Reduce Post-Op Pain. New research has found that relaxation and music, separately or together, significantly reduce patients' pain following major abdominal surgery. The study, published in the May issue of the journal Pain, found that these methods reduce pain more than pain medication alone. Led by Marion Good, PhD, RN, of Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, the study is supported by the National Institute of Nursing Research (NINR), at the National Institutes of Health. "This is important news for the millions of Americans who undergo surgery and experience postoperative pain each year," said Dr. Patricia A. Grady, director of the NINR.

    "Better pain management can reduce hospital stays and speed recovery, ultimately improving patients' quality of life." Dr. Good and her research team studied three groups of patients undergoing abdominal surgery. In addition to the usual pain medication, one group used a jaw relaxation technique, another group listened to music, and a third group received a combination of relaxation and music.

    Findings revealed that, after surgery, the three treatment groups had significantly less pain than the control group, which received only pain medication. "Both medication and self-care methods which involve patient participation are needed for relief," said Dr. Good.

    "These relaxation and music self-care methods provide more complete relief without the undesired side effects of some pain medications." The findings have important implications for the 23 million people who undergo surgery and experience postoperative pain annually in the United States. Pain can hamper recovery by heightening the body's response to the stress of surgery and increasing tissue breakdown, coagulation and fluid retention. Pain also interferes with appetite and sleep and can lead to complications that prolong hospitalization.

    Dr. Good and her research staff worked with 500 patients aged 18-70, who were undergoing gynecological, gastrointestinal, exploratory or urinary surgery. Prior to surgery, those in the music, relaxation or combination groups practiced the techniques. The relaxation technique consisted of letting the lower jaw drop slightly, softening the lips, resting the tongue in the bottom of the mouth, and breathing slowly and rhythmically with a three-rhythm pattern of inhale, exhale and rest. Patients in the music group chose one of five kinds of soothing music--harp, piano, synthesizer, orchestral or slow jazz.

    On the first and second days after surgery, all patients received morphine or Demerol for pain relief by pressing a button connected to their intravenous patient controlled analgesia pumps. The groups receiving the additional intervention used earphones to listen to music and relaxation tapes during walking and rest, while the control group did not. The research team measured the patients' pain before and after 15 minutes of bed rest and four times during walking to see if the sensation and distress of pain changed.

    Dr. Good found that during these two days postsurgery the three treatment groups had significantly less pain than the control group during both walking and rest. "Patients can take more control of their postoperative pain using these self-care methods," says Dr. Good. "Nurses and physicians preparing patients for surgery and caring for them afterwards should encourage patients to use relaxation and music to enhance the effectiveness of pain medication and hasten recovery."

    Dr. Good's findings have implications for future research into the effectiveness of self-care methods on other types of pain, including chronic pain, cancer pain, and pain of the critically ill.

    -----------------------------

    Vitamin D Lack Linked to Hip Fracture. Vitamin D deficiency in post-menopausal women is associated with increased risk of hip fracture, according to investigators at Brigham and Women's Hospital in Boston, Mass. In a group of women with osteoporosis hospitalized for hip fracture, 50 percent were found to have a previously undetected vitamin D deficiency. In the control group, women who had not suffered a hip fracture but who were hospitalized for an elective hip replacement, only a very small percentage had vitamin D deficiency, although one-fourth of those women also had osteoporosis. These findings were reported in the April 28, 1999, issue of the Journal of the American Medical Association.

    The study, conducted by Meryl S. LeBoff, MD; Lynn Kohlmeier, MD; Shelley Hurwitz, PhD; Jennifer Franklin, BA; John Wright, MD; and Julie Glowacki, PhD; of the Endocrine Hypertension Division, Department of Internal Medicine, and Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, was supported by grants from the National Institute on Aging (NIA) and the National Center for Research Resources (NCRR. These investigators studied women admitted to either Brigham and Women's Hospital or the New England Baptist Hospital, both in Boston, between January 1995 and June 1998.

    A group of 98 postmenopausal women who normally reside in their own homes were chosen for the study. Women with bone deterioration from other causes were excluded from the study.

    There were 30 women with hip fractures caused by osteoporosis and 68 hospitalized for elective joint replacement. Of these 68, 17 women also had osteoporosis as determined by the World Health Organization bone density criteria. All the participants answered questions regarding their lifestyle, reproductive history, calcium in their diet, and physical activity.

    Bone mineral density of the spine, hip, and total body were measured by dual X-ray absorptiometry (DXA) technique, as was body composition. Blood chemistry and urinary calcium levels were analyzed. The two groups of women with osteoporosis did not differ significantly in either time since menopause or bone density in the spine or hip. They did, however, differ in total bone density.

    The women admitted for a hip fracture had fewer hours of exercise than the control group. Fifty percent of the women with hip fractures were deficient in vitamin D, 36.7 percent had elevated parathyroid hormone (PTH) levels (a hormone which can stimulate loss of calcium from bone), and 81.8 percent had calcium in their urine, suggesting inappropriate calcium loss. Blood levels of calcium were lower in the women with hip fractures than in either elective group.

    These researchers propose that vitamin D supplementation at the time of fracture may speed up recovery and reduce risk of fracture in the future. Current Dietary Reference Intake Guidelines contain a daily recommendation of 400 IU of vitamin D for people aged 51 through 70 and 600 IU for those over age 70.

    "We know that a calcium-rich diet and regular weight-bearing exercise can help prevent osteoporosis. This new research suggests that an adequate intake of vitamin D, which the body uses to help absorb calcium, may help women to reduce their risk of hip fracture, even when osteoporosis is present," observed Dr. Evan C. Hadley, NIA Associate Director for geriatrics research.

    "Osteoporosis leads to more than 300,000 hip fractures each year, causing pain, frequent disability, and costly hospitalizations or long-term care. "Prevention of such fractures would greatly improve the quality of life for many older women and men, as well as significantly reduce medical costs." The bones in the body often undergo rebuilding. Some cells, osteoclasts, dissolve older parts of the bones. Then, bone-building cells known as osteoblasts create new bone using calcium and phosphorus.

    As people age, if osteoporosis develops, more bone is dissolved than is rebuilt, and the bones weaken and become prone to fracture. Also in many older persons, levels of vitamin D in the blood are low because they eat less or spend less time in the sun, which stimulates the body's own production of vitamin D.

    Experts do not understand fully the causes of osteoporosis. However, they do know that lack of estrogen which accompanies menopause, diets low in calcium, and lack of exercise contribute to the problem. Eighty percent of older Americans who face the possibility of pain and debilitation from an osteoporosis-related fracture are women. One out of every two women and one in eight men over the age of 50 will have such a fracture sometime in the future. These fractures usually occur in the hip, wrist, and spine.

    -----------------------------

    Sleep Apnea, Diabetes Link Found. Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes and more likely to suffer a stroke in the future, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published today in the Journal of Oral and Maxillofacial Surgery. Sleep apnea, a serious condition marked by loud snoring, irregular breathing and interrupted oxygen intake, affects an estimated nine million Americans. The culprit? Carrying too many extra pounds.

    "The blame falls squarely on excess weight gain," said Dr. Arthur H. Friedlander, associate professor of oral and maxillofacial surgery at the UCLA School of Dentistry and associate chief of staff at the Veterans Affairs Medical Center in Los Angeles. Surplus weight interferes with insulin's ability to propel sugars from digested food across the cell membrane, robbing the cells of needed carbohydrates. Diabetes results when glucose builds up in the bloodstream and can't be utilized by the body. Being overweight can also lead to obstructive sleep apnea, according to Friedlander.

    "When people gain too much weight, fatty deposits build up along the throat and line the breathing passages," he explained. "The muscles in this region slacken during sleep, forcing the airway to narrow and often close altogether." Reclining on one's back magnifies the situation. "When an overweight person lies down and goes to sleep," Friedlander said, "gravity shoves the fat in the neck backwards. This blocks the airway and can bring breathing to a halt."

    Friedlander tested the blood sugar of 54 randomly selected male veterans whom doctors had previously diagnosed with obstructive sleep apnea. He discovered that 17 of the 54 patients, or 31 percent, unknowingly suffered from adult-onset diabetes. Using the same sample, Friedlander also took panoramic X-rays of the men's necks and jaws. The X-rays indicated that 12 of the 54 patients, or 22 percent, revealed calcified plaques in the carotid artery leading to the brain.

    These plaques block blood flow, significantly increasing patients' risk for stroke. Seven of the 12, or 58 percent, were also diagnosed with diabetes. In dramatic comParison, the 17 patients diagnosed with diabetes showed nearly twice the incidence of blockage. Seven of the 17 men, or 41 percent, had carotid plaques. Only five of the 54 patients who displayed plaques did not have also diabetes. If he conducted this study today, Friedlander notes, he would likely find a higher number of diabetic patients. After he completed the study in 1997, the American Diabetes Association lowered its definition for diabetes from 140 to 126 milligrams of sugar per deciliter of blood.

    "This is the first time that science has uncovered a link between sleep apnea and diabetes," said Friedlander. "The data suggest that someone afflicted with both diabetes and sleep apnea is more likely to suffer a stroke in the future." "Persons going to the doctor for a sleep-apnea exam should request that their blood be screened for diabetes, especially if they are overweight," he cautioned. More than half of the individuals who develop diabetes as adults will need to modify their diet and take daily insulin in order to control the disease, he added.

    ------------------------------

    Stress, Surgery May Increase CA Tumors. Stress and surgery may increase the growth of cancerous tumors by suppressing natural killer cell activity, says a Johns Hopkins researcher.

    Malignancies and viral infections are in part controlled by the immune system's natural killer (NK) cells, a sub-population of white blood cells that seek out and kill certain tumor and virally infected cells. In a study using animal models, natural killer cell activity was suppressed by physical stress or surgery, resulting in a significant increase in tumor development.

    These findings suggest that protective measures should be considered to prevent metastasis for patients undergoing surgery to remove a cancerous tumor, according to Gayle Page, D.N.Sc., R.N., associate professor and Independence Foundation chair at the Johns Hopkins School of Nursing. "Human studies have already found a connection between the level of NK activity and susceptibility to several different types of cancer," says Page, an author of the study.

    "We sought to determine the importance of stress-induced suppression of NK activity and thus learn the effects of stress and surgery on tumor development. "Many patients undergo surgery to remove cancerous tumors that have the potential to spread. If our findings in rats can be generalized to such clinical settings, then these circumstances could increase tumor growth during or shortly after surgery." The research was conducted at Ohio State University College of Nursing and the Department of Psychology at UCLA, where Page held previous positions, and at Tel Aviv University.

    Results of the study are published in the March issue of the International Journal of Cancer. In laboratory studies, Page and her colleagues subjected rats to either abdominal surgery or physical stress, and then inoculated them with cancer cells. In the rats that had undergone surgery, the researchers observed a 200 to 500 percent increase in the incidence of lung tumor cells, an early indicator of metastasis, compared with rats that had not received surgery.

    The experiment also showed that stress increased lung tumor incidence and significantly increased the mortality in the animals inoculated with cancer cells. "Our results show that, under specific circumstances, resistance to tumor development is compromised by physical stress and surgical intervention," says Page.

    "Because surgical procedures are life-saving and cannot be withheld, protective measures should be considered that will prevent suppression of the natural killer cell activity and additional tumor development. "Researchers do not yet know how to prevent surgery-induced immune suppression, but early animal studies have shown increased use of analgesia reduces the risk."

    The study was funded by the National Institutes of Health, and the Chief Scientist of the Israeli Ministry of Health. Lead author was Shamgar Ben-Eliyahu, Ph.D., and other authors were Raz Yirmiya, Ph.D., and Guy Shakhar.

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    Quercetin and Bromelain - for better health.
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    Date: July 04, 2005 10:28 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Quercetin and Bromelain - for better health.

  • Maintains Tissue Comfort by Regulating Enzymes*
  • Helps Maintain Normal Blood Viscosity*
  • Bromelain May Enhance Quercetin Absorption
  • Benefits

    Down-regulates the Body’s Response to Environmental Challenges Quercetin is a member of the flavonoid family, a diverse group of low molecular-weight compounds found throughout the plant kingdom. Flavonoids exhibit numerous biological activities, many of which are directly beneficial to human health. Quercetin, which belongs to the “flavonol” subgroup, is one of the most versatile and important flavonoids. Quercetin has a broad range of activity, much of which stems from its interaction with calmodulin, a calcium-regulatory protein.1 Calmodulin transports calcium ions across cellular membranes, initiating numerous cellular processes. Quercetin appears to act as a calmodulin antagonist.1 Through this mechanism, quercetin functions at the cell-membrane level with a membrane-stabilizing action.2 Quercetin inhibits calmodulin-dependent enzymes present at cell membranes such as ATPases and phospholipase, thereby influencing membrane permeability.3 Quercetin affects other calmodulin-dependent enzymes that control various cellular functions, including the secretion of histamine from mast cells.4 A number of investigations have corroborated quercetin’s ability to reduce histamine secretion from mast cells in various tissues, and also from basophils.5,6,7,8,9,10

    Quercetin modifies the body’s response to antigenic substances.* Suppression of histamine secretion from mast cells is one of quercetin’s most clinically important effects. Quercetin acts on ATPase at the membranes of histamine-containing granules in mast cells.3 Mast-cell degranulation and subsequent release of histamine into the bloodstream is an integral part of the body’s response to environmental challenges.

    Maintains Tissue Comfort by Regulating Enzymes*

    Quercetin’s enzyme-inhibiting action extends to enzymes such as phospholipase, which catalyzes the release of arachidonic acid from phospholipids stored in cell membranes.4,10 Arachidonic acid serves as the key substrate for substances such as thromboxanes, inflammatory prostaglandins and leukotrienes. In addition, quercetin inhibits the enzymes cyclooxygenase and lipoxygenase, which catalyze the conversion of arachidonic acid into its metabolites.4,10,11,12 Reducing levels of these metabolites, as well as histamine levels, is beneficial in maintaining the normal comfort level of body tissues and structures.

    Quercetin has also been shown to limit the function of adhesion molecules on endothelial cells.13 Adhesion molecules are involved in physiologic processes that influence tissue comfort.13

    Bromelain is a complex substance derived from the pineapple stem largely composed of proteolytic (protein-digesting) enzymes. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.14,15 Several investigators, including Taussig16 and Ako, et. al.,17 have presented evidence that bromelain is a fibrinolytic agent, i.e., it induces the breakdown of fibrin, a plasma protein that blocks tissue drainage. The generally accepted mechanisms involve direct proteolysis of fibrin by bromelain and activation of plasmin, a serum protease.16 Plasmin acts on fibrinogen (the precursor to fibrin), forming peptides which stimulate PGE1, a prostaglandin that helps maintain tissue comfort.16

    Helps Maintain Health of Blood Vessels by Modifying Oxidation of LDL Cholesterol* — Quercetin’s Antioxidant Action Quercetin is a versatile and effective antioxidant that scavenges a variety of free-radicals such as hydroxyl and lipid peroxy radicals.18 Quercetin also chelates ions of transition metals such as iron, which can initiate formation of oxygen free radicals.18 LDL cholesterol is vulnerable to oxidation by lipid peroxides. Oxidized LDL is absorbed by macrophages and arterial endothelial cells, leading to the formation of “foam cells,” and eventually plaque deposits, in arterial walls. Quercetin has been shown to protect LDL from oxidation, both by lipid peroxides and transition metal ions.19

    Helps Maintain Normal Blood Viscosity*

    Quercetin inhibits blood platelet aggregation (clumping), by potentiating PGI2, an anti-aggregatory prostaglandin, and by raising platelet cyclic AMP levels.20 Human studies have revealed that bromelain also reduces platelet aggregation.21 These properties qualify both quercetin and bromelain as valuable dietary ingredients for maintaining cardiovascular health.*

    Bromelain May Enhance Quercetin Absorption

    In addition to the actions described above that support the effects of quercetin, bromelain may also assist the absorption of quercetin in the G.I. tract. (Quercetin is generally believed to be poorly absorbed, although a recent study by Hollman et. al.,22 which concluded that humans do in fact absorb appreciable amounts of quercetin, contradicts this assumption.) Studies have shown that bromelain enhances absorption of antibiotics, presumably by increasing permeability of the gut wall.23, 24 Given that quercetin is a low molecular-weight compound, it is plausible that simultaneously ingested bromelain likewise enhances quercetin absorption.

  • *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
  • Scientific References

    1. Nishino, H., et. al., “Quercetin interacts with calmodulin, a calcium regulatory protein.” Experientia 1984;40:184-5.
    2. Busse, W.W., Kopp, D.E., Middleton, E., “Flavonoid modulation of human neutrophil function.” J. Allergy Clin. Immunol. 1984;73:801-9.
    3. Havsteen, B,. “Flavonoids, a class of natural products of high pharmacological potency.” Biochemical Pharmacology 1983;32(7):1141-48.
    4. Middleton, E., “The Flavonoids.” Trends in Pharmaceutical Sciences 1984;5:335-8.
    5. Otsuka, H. et. al., “Histochemical and functional characteristics of metachromatic cells in the nasal epithelium in allergic rhinitis: Studies of nasal scrapings and their dispersed cells.” J. Allergy Clin. Immunol.1995;96:528-36.
    6. Fox, C.C., et. al., “ComParison of human lung and intestinal mast cells.” J. Allergy and Clin. Immunol. 1988;81:89-94.
    7. Pearce, F.L., Befus, A.D., Bienenstock, J., “Mucosal mast cells III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.” J. Allergy and Clin. Immunol. 1984;73:819-23.
    8. Middleton, E. Drzewiecki, G., Krishnarao, D., “Quercetin: an inhibitor of antigen-induced human basophil histamine release.” J. of Immunology 1981;127(2):546-50.
    9. Bennett, J.P., Gomperts, B.D., Wollenweber, E.,“ Inhibitory effects of natural flavonoids on secretion from mast cell and neutrophils.” Arzneim. Forsch/Drug Res. 1981;31(3):433-7.
    10. Middleton, E. Drzewiecki G., “Naturally occurring flavonoids and human basophil histamine release.” Int. Archs Allergy appl. Immun. 1985;77:155-7.
    11. Yoshimoto, T. et. al., “Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase.” Biochemical and Biophysical Research Communications 1983;116(2):612-18.
    12. Della Loggia, R., et. al., “Anti-inflammatory activity of benzopyrones that are inhibitors of cyclo- and lipo-oxygenase.” Pharmacological Research Communications 1988; 20(Supp. V):91-94.
    13. Middleton, E., Suresh, A., “Quercetin inhibits lipopolysaccharide-induced expression of endothelial cell intracellular adhesion molecule-1.” Int. Arch. Allergy Immunol. 1995;107:435-6.
    14. Taussig, S.J., Batkin, S., “Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application.” An Update Journal of Ethnopharmacology 1988;22:191-203.
    15. Lotz-Winter, H., “On the pharmacology of bromelain: An update with special regard to animal studies on dose-dependent effects.” Planta Medica 1990;56:249-53.
    16. Taussig, S.J., “The mechanism of the physiological action of bromelain” Medical Hypothesis 1980;6:99-104.
    17. Ako, H. Cheung, A.H.S., Matsuura, P.K., “Isolation of a fibrinolysis activator from commercial bromelain.” Arch. Int. Pharmacodyn. 1981;284:157-67.
    18. Afanas’ev, I.B. et. al., “Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation.” Biochemical Pharmacology 1989;38(11):1763-69.
    19. De Whalley, C.V., “Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages.” Biochemical Pharmacology 39(11):1743-50.
    20. Beretz, A. Stierle, A., Anton, R. Cazenave, J., “Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin.” Biochemical Pharmacology 1981;31(22):3597-600.
    21. Heinicke, R. van der Wal, L. Yokoyama, M., “Effect of bromelain (Ananase®) on human platelet aggregation. ”Experientia 1972;28(7):844.
    22. Hollma, P. et. al., “Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers.” Am. J. Clin. Nutr. 1995;62:1276-82.
    23. Giller, F.B., “The effects of bromelain on levels of penicillin in the cerebrospinal fluid of rabbits.” A., J. Pharm. 1962;134:238-244.
    24. Bodi, T., “The effect of oral bromelain on tissue permeability to antibiotics and pain response to bradykinin; double-blind studies on human subjects.” Clin. Med. 1965;72:61-65



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    GLISODIN POWER - Superoxide Dismutase (SOD)
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    Date: June 29, 2005 10:54 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GLISODIN POWER - Superoxide Dismutase (SOD)

    Most people know that antioxidants found in food are critical for health and longevity, but did you know that the human body has its own antioxidant defense system? Superoxide dismutase (SOD) is an internal antioxidant manufactured by the body as the first line of defense against free radical damage. Unfortunately, high levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help.

    Source Naturals introduces GLISODIN POWER, an innovative approach to antioxidant supplementation. Scientific research shows that GliSODin® supports the body’s own production of superoxide dismutase. GLISODIN POWER is a patented, orally effective, 100% vegetable compound comprised of gliadin, a wheat protein extract bound to superoxide dismutase derived from canteloupe.

    Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to your cells and tissues. Free radicals have unpaired electrons that can damage living cells and compromise the proper function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of antioxidants to minimize this negative effect.

    First Line of Defense

    There are two classes of antioxidants-external and internal. External antioxidants are supplied to the body by the foods we eat or the supplements we take. They include vitamins A, C and E, selenium, and other antioxidants found in fruits and vegetables. Internal antioxidants are naturally present in every cell of your body. The internal antioxidant defense system includes the enzymes superoxide dismutase (SOD), catalase and glutathione peroxidase. They are the first line of defense against oxidative stress. SOD transforms the superoxide radicals into ions that are less reactive. The superoxide radicals, which are byproducts of normal cell processes, can damage cells if their levels are not controlled. The other enzymes then transform the less reactive ions in a process called dismutation. The superoxide dismutase enzyme gets its name from this process. Research indicates that SOD plays an important role in protecting neurons from oxidative damage.

    Super Antioxidant: SOD

    SOD levels decline with age, while free radical production increases. SOD occurs naturally in barley grass, broccoli, Brussels sprouts, cabbage, wheat grass, melon and most green plants. Unfortunately, when taken orally the SOD enzyme is usually destroyed in the digestive process. GliSODin is a new form of SOD that withstands the digestive process and promotes SOD production by the body. This breakthrough technology combines a vegetable source of SOD extracted from melon with gliadin, a wheat protein. Scientific studies have shown that GliSODin promotes the natural production of SOD in the body. Research has also shown that it protects against oxidative stress and provides an optimal defense against free radicals.

    Wellness Revolution

    Innovative natural products such as GLISODIN POWER, are part of the Wellness Revolution. Taking personal responsibility for your health is at the heart of this revolution. Your local health food outlet is your source for nutritional education and quality products. Source Naturals is pleased to partner with these outlets to bring you the groundbreaking nutritional science of GLISODIN POWER.

    References:
    Vouldoukis, I. et al. Oral supplementation of the antioxidant enzyme superoxide dismutase in Wheat Gliadin Biopolymers promotes the antioxidant defense system. Bernard Dugas, Isocell Nutra, 53 bd du General Martial Valin, 75015 Paris, France. (Article submitted to the American Journal of Clinical Nutrition, Jan 2002). Claus, M et al. 2004. Oral SOD and oxidative cell stress: Influence of an orally effective SOD on hyperbaric oxygen-related cell damage. Free Radical Research 38 (9): 927-932. Stella, V. et al. 1995. Gliadin films. I. Preparation and in vitro evaluation as a carrier for controlled drug release. International Journal of Pharmaceutics 121: 117-121. Isocell SA, France is the owner of US Patent Nos. 6,045,809 and 6,426,068B1 and trademark for GliSODin®.



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    Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.
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    Date: June 29, 2005 09:37 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.

    Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.

    In our high-powered world, countless Americans are searching for a wholesome, natural product to help them maintain a positive outlook and sense of well-being. The remarkable botanical, St. John’s wort, is well-known for its established history of safe use. Now Source Naturals offers you the first and only once-daily, TIMED-RELEASE ST. JOHN’S WORT. This premium botanical is manufactured in a special cellulose base, which is tested to release St. John’s wort over a 12-hour period.

    Source Naturals tests each production lot of TIMED-RELEASE ST. JOHN’SWORT. This exclusive supplement is standardized to 0.3% hypericin, yielding 2.7 mg in every convenient daily dose— the amount shown in research to support mild to moderate maintenance of a positive mood. At a time when our emotional well-being is challenged by unprecedented stress levels, research into the most convenient and effective natural remedies is critical. Source Naturals is your connection to this research, dedicated to quickly bringing you the benefts of the latest emerging wellness strategies.

    Popular Choice For a Positive Mood—Now Even Better!

    St. John’s wort, or Hypericum perforatum, has been valued by diverse cultures as far back as the Middle Ages for its ability to support a positive outlook and sense of well-being. Today modern consumers are experiencing the benefits of this renowned herb, which include mood-brightening, relaxation, alertness, and a sense of overall well-being. Unlike other supplements on the market, Source Naturals TIMED-RELEASE ST. JOHN’SWORT is produced using the most advanced scientific methods. The result is a supplement that offers the once-daily convenience today’s consumers have come to expect.

    Clinical Trials

    A review of 23 randomized clinical trials encompassing 1757 subjects was reported in the British Medical Journal. It showed that St. John’s wort was more effective than placebo for mild to moderate maintenance of a positive mental outlook.

    The Beneficial Constituents

    The beneficial constituents of the St. John’s Wort plant are believed to be the naphthodianthrones, especially hypericin and pseudohypericin, and a wide variety of flavonoids. Source Naturals TIMED-RELEASE ST. JOHN’S WORT is standardized to consistently yield 0.3% hypericin. Each convenient once-daily dose contains 900 mg of St. John’s Wort extract, yielding 2.7 mg hypericin. This is the optimal amount found in most studies to support a positive outlook and sense of wellbeing. Benefits may be experienced within 4 to 6 weeks of initial use.

    Emotional Well-Being: Important Component of the Wellness Revolution

    Source Naturals is pleased to join with your local health food store in offering you the next generation in St. John’s wort supplementation. TIMED RELEASE ST. JOHN’SWORT can help you support a positive mood with the remarkable properties of the plant world, exclusively formulated for once-daily convenience. This advanced product reflects today’s revolution in natural health care, offering you the benefits of natural, cuttingedge supplementation.

    References
    Behnke K., Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression, Adv. Ther. 2002, Jan-Feb; 19(1): 43-52. Klaus, Linde et. al., St. John’s Wort for depression— an overview and meta-analysis of randomized clinical trials, British Medical Journal, 1996; 313:253-258 (3 August). Upton R, (ed.), et al. Monograph: St. John’s wort. American Herbal Pharmacopoeia. Special Supplement in HerbalGram. 1997;40:Sl-32. Woelk H., ComParison of St. John’s wort and imipramine for treating depression: randomized controlled trial., British Medical Journal, 2000, Sep 2; 321(7260):536-9.



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    ALPHA GPC - Improves Mental Performance
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    Date: June 28, 2005 06:21 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: ALPHA GPC - Improves Mental Performance

    The quality of our life experience—and our ability to live life to the fullest—is a direct result of optimal brain function. Only a few years ago, nothing could be done to stem the tide of poor circulation, forgetfulness and “mental fog.” But neurological science exploration has identified a fundamental brain compound critical to attention, learning, memory, and even the higher cognitive functions of reasoning and intuition. Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for convenience) is crucial to neuronal function and structure. Derived from purified soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in the brain, helping to maintain neuronal structure integrity. Source Naturals provides an easy and convenient means to profoundly impact the very nexus of our body and mind.

    GPC Is Unique

    No other nutritional compound comes close to GPC in its ability to boost critically important acetylcholine levels. Found in both the brain and the peripheral nervous system (including the nerve-muscle junctions), acetylcholine is a key nerve messenger molecule, or neurotransmitter. Aging brains are characterized by functional deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly bioavailable supplement that boosts acetylcholine levels to improve cognitive function. It is also a major choline reservoir, helping to protect the brain against damage from poor circulation and potentially toxic metabolites.

    Deficiencies in acetylcholine can cause the body to break down phosphatidylcholine for its choline content, leading to the death of brain cells. Yet in controlled clinical trials of middle-aged subjects taking GPC, reaction time was enhanced and there was improved energy generation and electrical coordination in the brain. For older subjects, double-blind trials demonstrated that GPC had superior benefits over certain other brain nutrients for mental focus, recall, verbal fluency—a unique, marked overall enhancement of mental performance. GPC is an example of what the great Linus Pauling referred to as “orthomolecules,” that is, molecules that are “orthodox” or “correct” for the body. GPC excels as a protective nutraceutical for memory loss and mood enhancement. It protects cells of the brain (and other organs) from damage, shielding a range of important biomolecules against toxin build-up.

    Extensive Clinical Testing

    In clinical trials that involved more than 5,000 patients, GPC showed marked improvement in overall brain performance. Depending on the particular trial, 50-70 percent of the patients who received GPC had their mental functions improved to a degree “meaningful to life quality.” GPC has shown revitalizing effects on the declining brain, and preliminary evidence suggests GPC may act on the pituitary gland to partially restore its capacity to make vital for cell maintenance and longevity. Other unique brain features of GPC are its benefits for attention and recall in young healthy adults, and its superior bioavailability. GPC readily crosses the bloodbrain barrier to raise brain choline levels within a few hours following oral intake. GPC helps with body-mind integration by being a ready reservoir for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation, expansion, renewal and repair, as well as in the “agility” or adjustments of the circuitry that occur during adult life. In addition, an animal study has shown that GPC increases the release of GABA (gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter in the brain. It acts as a “balancer” for the brain and helps induce relaxation and sleep. Without sufficient GABA, neurons fire at random, unable to make sense of incoming signals. GABA helps minimize “neural noise,” making it easier to focus and concentrate.

    Why you should take GPC:

  • • Mental performance is improved at all ages (including attention, concentration and recall).
  • • GPC supports mind-body “focus,” including reflexes, response time, and endurance.
  • • GPC has benefits for healthy aging.
  • • GPC protects all the body’s cells through its unique osmolyte capacities.
  • • GPC is naturally present in very high concentrations in healthy cells, and also in mother’s milk, where it is the major source of choline for the developing brain. While it may be the single best nutrient for the brain, GPC is also a broader supplement for active living and healthy aging because it supports optimal metabolic function in all the organs. GPC has a metabolically privileged relationship with DHA (docosahexaenoic acid, omega-3). These are combined to make cell membrane phospholipids essential to metabolic efficiency in kidney, liver, and muscle function, and for sperm maturation. These body-wide functions, combined with its known brain benefits, allow GPC to support the functional integration of the brain with the other organs. Don’t pass up this newly discovered option to enhance the quality of your life, health and higher mental functions. Explore your nearby natural food outlet and utilize discoveries such as GPC, which has already improved the health and chances of longevity for the millions who have been wise enough to join the Wellness Revolution.

    References:
    Parnetti L, Amenta F, Gallai V. 2001. Choline alfoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data. Mechs Aging Dev. 22: 2041. Canal N, et al. 1993. ComParison of the effects of pretreatment with choline alfoscerate, idebenone, aniracetam and placebo on scopolamine-induced amnesia. Le Basi Raz Ter. 23: 102. De Jesus Moreno Moreno M. 2002. Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, doubleblind, randomized, placebo-controlled trial. Clin Ther. 25: 178.



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    REFERENCES
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    Date: June 25, 2005 08:13 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: REFERENCES

    REFERENCES

    1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.

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    CHITOSAN: The Fiber that Binds Fat
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    Date: June 25, 2005 07:55 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CHITOSAN: The Fiber that Binds Fat

    Overview

    Chitosan is a natural product that inhibits fat absorption. It has the potential to revolutionize the process of losing weight and by so doing, reduce the incidence of some of the most devastating Western diseases we face today. Chitosan is indigestable and non-absorbable. Fats bound to chitosan become nonabsorbable thereby negating their caloric value. Chitosan-bound fat leaves the intestinal tract having never entered the bloodstream. Chitosan is remarkable in that it has the abilty to absorb an average of 4 to 5 times its weight in fat.60

    The same features that allow chitosan to bind fats endow it with many other valuable properties that work to promote health and prevent disease. Chitosan is a remarkable substance whose time has come.


    Chitosan: A Brief History

    Chitin, the precursor to Chitosan, was first discovered in mushrooms by the French professor Henri Braconnot in 1811.61 In the 1820’s chitin was also isolated from insects.62 Chitin is an extremely long chain of N-acetyl-D-glucoseamine

    FIGURE 2.
    a) Chitosan full structure
    b) Abbreviated Chitosan structure
    c) Fanciful "crab oligomer" Chitosan structure showing functional claw

    glucoseamine units. Chitin is the most abundant natural fiber next to cellulose and is similar to cellulose in many respects. The most abundant source of chitin is in the shells of shellfish such as crab and shrimp. The worldwide shellfish harvest is estimated to be able to supply 50,000 tons of chitin annually.63 The harvest in the United States alone could produce over 15,000 tons of chitin each year.64

    Chitin has a wide range of uses but that is the subject of another book. Chitosan was discovered in 1859 by Professor C. Rouget.65 It is made by cooking chitin in alkali, much like the process for making natural soaps. After it

    ----------------------------------
    • Waste Water Purification • Stabilizing Oil Spills • Stabilizing Fats in Food Preparation • Antibacterial Protection for Seeds • Flavor Stabilizer • Stabilizes Perishable Fruits/Vegetables • Ion Exchange Media • Bacterial Immobilizer • Cosmetic and Shampoo Additive • Tableting Excipient • Absorbant for Heavy Metal Removal
    Table 5. Industrial Uses of Chitosan 66-75

    ----------------------------------
    • Absorbs and Binds Fat • Promotes Weight Loss • Reduces LDL Cholesterol • Boosts HDL Cholesterol • Promotes Wound Healing • Antibacterial/Anticandida/Antiviral • Acts as Antacid • Inhibits the Formation of Plaque/Tooth Decay • Helps Control Blood Pressure • Helps Dental Restoration/Recovery • Helps to Speed Bone Repair • Improves Calcium Absorption • Reduces Levels of Uric Acid
    Table 6. Health and Nutrition Uses of Chitosan 60,66,77-107

    is cooked the links of the chitosan chain are made up of glucosamine units. Each glucosamine unit contains a free amino group. These groups can take on a positive charge which gives chitosan its amazing properties. The stucture of chitosan is represented schematically in Figure 2. Research on the uses of chitin and Chitosan flourished in the 1930s and early 1940s but the rise of synthetic fibers, like the rise of synthetic medicines, overshadowed the interest in natural products. Interest in natural products, including chitin and chitosan, gained a resurgence in the 1970s and has continued to expand ever since. Uses of Chit osan Some of Chitosan's major uses—both Industrial and Health and Nutritional—are listed in Tables 5 and 6.

    Water Purification

    Chitosan has been used for about three decades in water purification processes. 67 When chitosan is spread over oil spills it holds the oil mass together making it easier to clean up the spill. Water purification plants throughout the world use chitosan to remove oils, grease, heavy metals, and fine particulate matter that cause turbidity in waste water streams.

    Fat Binding/ Weight Loss

    Like some plant fibers, chitosan is not digestible; therefore it has no caloric value. No matter how much chitosan you ingest, its calorie count remains at

    ------------------------------
    Dietary Fiber % Fat Excreted Dietary Fiber %Fat Excreted Chitosan 50.8 + 21.6 Carrageen 9.6 + 1.9 Kapok 8.3 + 1.1 Sodium Alginate 8.1 + 2.2 Pectin 7.4 + 1.9 Locust Bean 6.0 + 1.8 Guar 6.0 + 1.7 Konjak 5.2 + 0.6 Cellulose 5.1 + 2.1 Karaya 4.9 + 1.5 Acacia 4.6 + 0.9 Furcellaran 4.4 + 0.9 Chitin 4.3 + 1.0 Agar 2.8 + 0.4
    TABLE 7. Effects of Dietary Fibers on Fecal Lipid Excretion 109,110

    fibers, chitosan’s unique properties give it the ability to significantly bind fat, acting like a “fat sponge” in the digestive tract. Table 7 shows a comParison of chitosan and other natural fibers and their ability to inhibit fat absorption. Under optimal conditions, Chitosan can bind an average of 4 to 5 times its weight with all the lipid aggregates tested.60 (NOTE: This assessment was made without the addition of ascorbic acid which potentiates this action even further.77 Studies in Helsinki have shown that individuals taking chitosan lost an average of 8 percent of their body weight in a 4-week period.76 Chitosan has increased oil-holding capacity over other fibers.108 Among the abundant natural fibers, chitosan is unique. This uniqueness is a result of chitosan’s amino groups which make it an acid absorbing (basic) fiber. Most natural fibers are neutral or acidic. Table 7 summarizes the in vivo effects in animals of various fibers on fecal lipid excretion. As can be seen from the results listed, ingestion of chitosan resulted in 5-10 times more fat excretion than any other fiber tested. D-Glucosamine, the building block of chitosan, is not able to increase fecal fat excretion. This is due to the fact that glucosamine is about 97 percent absorbed while chitosan is nonabsorbable. Fats bound to glucosamine would likely be readily absorbed along with the glucosamine. Chitosan, on the other hand, is not absorbed and therefore fats bound to chitosan can not be absorbed.

    Cholesterol Control

    Chitosan has the very unique ability to lower LDL cholesterol (the bad kind) while boosting HDL cholesterol (the good kind).78 Laboratory tests performed on rats showed that “chitosan depresses serum and liver cholesterol levels in cholesterol- fed rats without affecting performance, organ weight or the nature of the feces.”79 Japanese researchers have concluded that Chitosan “appears to be an effective hypocholesterolemic agent.”80 In other words, it can effectively lower blood serum cholesterol levels with no apparent side effects. A study reported in the American Journal of Clinical Nutrition found that Chitosan is as effective in mammals as cholestryramine (a cholesterol lowering drug) in controlling blood serum cholesterol without the deleterious side effects typical of cholestryramine. 81 Chitosan decreased blood cholesterol levels by 66.2 percent.82 It effectively lowered cholesterol absorption more than guar gum or cellulose.83 Laboratory test results indicated that a 7.5% chitosan formula maintained adequate cholesterol levels in rats, despite a dramatic increase in the intake of cholesterol. 84

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    Treating and Preventing Age-Related Mental Disorders
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    Date: June 25, 2005 11:24 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Treating and Preventing Age-Related Mental Disorders

    Treating and Preventing Age-Related Mental Disorders

    Ginkgo biloba may be of great value in cases of age-related mental dysfunction including senility, Alzheimer’s disease and diminished memory. In Paris, P. R. Michil conducted a double-blind study in which 50

    patients with moderate senile dementia were given either ginkgo or a placebo. Patients treated with ginkgo extract showed a significant improvement in their mood, sociability, and vigilance. Senility in the elderly is frequently the result of insufficient blood and oxygen flow to brain cells. Anytime this type of insufficiency occurs, short-term memory loss, ve rtigo, headache, malaise or depression can result. An extract derived from ginkgo leaves offers significant hope to anyone who suffers from diminished blood flow to the brain.

    In another large open trial involving 112 geriatric patients who suffered from inadequate cerebral blood flow, 120 mg. of ginkgo biloba extract was administered. The results showed a significant regression of pre-existing symptoms.5 What this study implies is that so-called “age - related disorders,” including senile dementia, may be caused by reduced blood flow to the brain rather than the actual degeneration of nerve cells. Ginkgo appears to increase oxygen utilization in brain tissue, which also enables neural cells to metabolized sugar more effectively.6

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    GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....
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    Date: June 21, 2005 05:25 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....

    GPC (GlyceroPhosphoCholine): Versatile Life Support Nutrient

    Parris Kidd, Ph.D.

  • GPC - Marked Benefits to the Brain
  • GPC Supports Normal Brain Function
  • GPC Works Through Multiple Mechanisms
  • Dosing, Safety, Tolerability, Compatibility
  • GPC: Nutrient for All Ages
  • GPC or GlyceroPhosphoCholine (pronounced gli-sero-fos-fo-ko-lean) is a nutrient with many different roles in human health. It reaches extremely high concentrations within our cells, and its abundance in mother's milk suggests it is crucial to life processes. Clinically, GPC has been most intensively researched for its brain benefits. Biologically, it has great importance for the skeletal "voluntary" muscles, the autonomic nervous system, kidneys, liver, and reproductive organs. GPC goes beyond being a brain nutrient; it is a nutrient for vitality and long life.

    Marked Benefits to the Brain

    As a dietary supplement, GPC's brain benefits are unique. It boosts mental performance in healthy young people, as shown by three double-blind trials. In trials on middle aged subjects, GPC improved several physiologic measures of mental performance: reaction time, visual evoked potential, and EEG delta slow waves. In the elderly, GPC improves mental performance and provides noticeable revitalisation. In 11 human trials with 1,799 patients, memory, attention, and other cognitive measures improved. So did mood (including irritability and emotional lability), and patients often developed renewed interest in relatives and friends. GPC was well tolerated, and generated no bad drug interactions. A large trial on elderly subjects with memory challenges published in 2003 concluded GPC had significant benefits for these individuals.

    GPC Supports Normal Brain Function

    Circulatory deprivation or surgery can challenge healthy brain function. GPC can speed recovery and support improved quality of life. In four trials with GPC on 2,804 subjects who experienced difficulties under these circumstances, up to 95% showed good or excellent improvement. GPC consistently improved space-time orientation, degree of consciousness, language, motor capacity, and overall quality of life. The investigators concluded GPC offered marked benefits, with an excellent benefit-to-risk profile. Up to half of patients who survive bypass surgery experience problems with memory and other mental performance. A double-blind trial conducted with bypass survivors for six months determined that the GPC group had no remaining memory deterioration, while the placebo group failed to improve.

    GPC Works Through Multiple Mechanisms

    GPC supports human health through a variety of mechanisms:

    1. It helps keep choline and acetylcholine available to the tissues. Choline is an essential nutrient and GPC appears to be the body's main choline reservoir. GPC in mother's milk represents the baby's main source of dietary choline. Acetylcholine (ACh) is an important substance employed extensively throughout the body. ACh is a major brain transmitter; the motor nerves use ACh to drive the skeletal ("voluntary") muscles; the autonomic nervous system uses it to pace all the organs. ACh is also central to mental and physical endurance, and mind-body coordination.

    2. GPC is a major cell-level protectant, not as another antioxidant but in pivotal roles of osmotic pressure regulator and metabolic antitoxin. GPC for osmotic regulation can reach very high concentrations in the kidney, bladder, liver, brain, and other organs. As metabolic protectant, GPC shields proteins against urea buildup.

    3. GPC is a major reservoir for cell membrane omega-3 phospholipids. These substances are the major building blocks for cell membranes. Enzymes couple GPC with the omega-3 fatty acid DHA, to make the phospholipid PC-DHA. This makes membranes especially fluid, enabling membrane proteins to perform with better efficiency. GPC produces PC-DHA in the skeletal muscles, wherein fluidity is essential for contraction. Muscles that function abnormally can show GPC deficiency.

    4. GPC contributes to both male and female in reproduction. As spermatozoa mature, GPC is used to make PC-DHA that makes their membranes fluid to enable motility. With men, the lower their semen GPC the greater the likelihood of poor sperm motility and with it, infertility. Once semen is inserted into the female, an enzyme in uterine secretions breaks down the semen's GPC into substances that energize the sperm to achieve fertilization.

    Dosing, Safety, Tolerability, Compatibility

    Oral intake of GPC in the clinical trials was usually 1,200 milligrams (mg) per day, taken early in the day on an empty stomach. A reasonable dietary supplementation regimen is 1200 mg/day, taken in divided doses (AM and PM) between meals for 15-30 days, and thereafter 600 mg/day for maintenance. Symptomatic subjects can take 1200 mg/day until adequate improvement is achieved. Young, healthy subjects may experience benefit from daily intakes as low as 300 milligrams. GPC is very safe, being compatible with vitamins and nutrients and with pharmaceuticals. In clinical trial comParisons, GPC's benefits surpassed the nutrients acetylcarnitine and CDP-choline.

    GPC: Nutrient for All Ages

    GPC is unmatched for its support of active living and healthy aging. In some 23 clinical trials GPC improved mental performance in all functional categories. GPC can revitalize the aging brain, facilitating growth hormone (GH) release and boosting nerve growth factor actions. GPC's ample presence in human mother's milk suggests it could be conditionally essential. By supporting mental integrity, mind-body integration, the autonomic system, and the body's other organs, GPC enhances the active lifestyle. GPC is remarkable nutritional support for optimal health at any age.

    Parris M. Kidd, PhD is a cell biologist trained at the University of California, Berkeley and San Francisco. Since entering the dietary supplement field in 1983, he has published many in-depth reviews of integrative medicine in the journal Alternative Medicine Reviews, and is science columnist for totalhealth magazine. Dr. Kidd is internationally recognized for his accomplishments in dietary supplement product development, documentation and quality control.

    Disclaimer: the above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider.



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    Vitanet ®

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    Building the Burn
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    Date: June 14, 2005 12:09 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Building the Burn

    Building the Burn by Marjorie Flakowitz Energy Times, June 11, 2004

    When was the last time you exercised? During the past decade, the number of obese Americans has jumped by 50%. A big factor in this increase: lack of physical activity.

    Today, technological society seems to make everyday life effortless: car windows retreat at the push of a button, remote controls keep couch potatoes from budging off the cushions and video games have replaced non-cyber ball playing. Americans don't move around and burn off the calories they eat. Instead, our sedentary ways are causing big stomach bulges and a big bulge in health problems linked to being overweight.

    Want to lose those pounds? Consuming the right nutrients and pounding the pavement are a great start.

    Number of Large Americans Grows Larger

    Fifty-five out of every 100 Americans are now overweight. And the numbers continue to surge. To take yourself out of these alarming statistics, plan a consistent exercise program. If the thought of sweating during strenuous workouts at the gym scares you, relax. You don't have to do that much. According to a long list of research, a few half-hour walks a week can put you on the road to weight loss.

    For instance, researchers at Duke found that walking a total of only 12 miles a week can help you control your weight even if you're not dieting (Archives of Internal Medicine 1/12/04). Of course dieting and taking the right supplements will help you lose weight a little faster, but walking burns off the pounds.

    In the study at Duke, scientists gathered about 180 overweight, sedentary people and assigned them to one of four groups. The first group had to jog about 20 miles a week. The second group jogged 12 miles a week. The third group walked 12 miles, and the last group didn't do a thing.

    " We found that the two low-exercise groups lost both weight and fat, while those in the more intensive group lost more of each in a 'dose-response' manner," says Cris Slentz, PhD, one of the researchers. " Simply put, the more you exercise, the more you benefit. Just as importantly, the control group of participants who performed no exercise gained weight over the period of the trial."

    Everybody who was exercising lost weight; their stomachs and hips shrank. The folks who did nothing didn't just stay at the same weight; their weight went up.

    Dr. Slentz adds, "From the perspective of prevention, it appears that the 30 minutes per day will keep most people from gaining the additional weight associated with inactivity. Given the increase in obesity in the US, it would seem likely that many in our society may have fallen below this minimal level of physical activity required to maintain body weight."

    Enzyme Help

    Of course, limiting the carbohydrates you consume and eating more protein at the same time as you exercise can help you lose weight more effectively. To help your body utilize protein more fully to fuel your exercise, many experts recommend taking enzyme supplements.

    One of the most valuable enzyme combinations in this process is Aminogen(r), an all-natural, patented plant enzyme that assists the digestive tract in liberating the amino acids that are the building blocks of dietary protein. By helping separate these amino acids, absorption is boosted through the walls of the small intestines and your metabolism is better able to take up proteins and use them.

    Add Chromium to Exercise

    The mineral chromium is another supplement found helpful in aiding weight loss. An eight-week study at the University of Texas, Austin, compared weight loss among obese women who exercised and took chromium with the number of pounds that were lost by women performing the same amount of exercise without taking supplements (Medicine & Science in Sports & Exercise 1997; 29:992-8).

    The result: women taking chromium lost a significantly greater amount. How does chromium work? A study at the University of Vermont found that chromium may help muscles take blood sugar (glucose) out of the blood more effectively by improving what's called insulin sensitivity (18th International Diabetes Federation Congress, Paris, 8/03).

    Sensitizing Insulin

    Insulin is released by the pancreas to help cells take in glucose. By exercising and keeping your weight down, and becoming more insulin sensitive, you potentially reduce your chances of getting diabetes. The cells quickly respond to insulin and blood sugar stabilizes.

    On the other hand, when insulin sensitivity drops significantly, the body may suffer what's called insulin resistance, a pre-diabetic condition that complicates and slows the removal of sugar from the blood. The Vermont researchers found that chromium increases the activity of a protein called Akt phosphorylation. This is a natural substance made by the body that makes cells more sensitive to insulin and speeds the movement of blood sugar into cells, where it can be burned for energy. So, in combination with exercise, which also helps the body become more responsive to insulin, chromium may help keep blood sugar under control.

    As Sandra Woodruff points out in her book Secrets of Good Carb, Low Carb Living (Avery/Penguin), "[P]hysical activity boosts the body's ability to process carbohydrate and helps reduce insulin resistance....Exercise acts much like an insulin-sensitizing drug to make the body's cells more responsive to insulin, which enables them to remove sugar from the blood more efficiently." The results of exercise and getting sufficient chromium can help support weight loss and healthy blood sugar levels. The Vermont research team found that the exercising chromium takers boosted their insulin sensitivity by almost 9%.

    Building a Lean Body

    A prime benefit of exercising while you lose weight is that physical activity builds muscle tissue. Muscle tissue, even at rest, burns more calories than fat cells, so having extra muscle means you can eat more and still maintain or lose weight. An aid in this process is Coleus forskohlii root, Benth., a plant that originated in India. Research shows that forskohlii furthers molecular energy processes within cells that support the development of lean body tissue (muscle) and the enzymatic reactions that break down fat.

    In a study of about two dozen women who took forskohlii extract, researchers found that taking this supplement was associated with feeling more energetic and less hungry (Experimental Biology meeting, 2002). According to Vladimir Badmaev, PhD, who has studied forskohlii, this herb's help in supporting lean body tissue is crucial to maintaining a healthy weight.

    " In highly overweight individuals, fat tissue can constitute up to 70% of body weight. The remaining proportion of body composition corresponds to the lean body mass. Lean body mass is composed of muscle, vital organs, bone, connective and other non-fatty tissues in the body," says Dr. Badmaev.

    " The body's metabolic rate is in direct proportion to the amount of lean body mass. Therefore, safely maintaining or increasing lean body mass is an important consideration for any weight-loss strategy."

    The Skinny on Calcium

    Calcium, long known for its ability to strengthen bones, is now turning out to play a key role in weight maintenance as well. In one study, obese mice who were put on calorie-restricted diets lost body fat when fed extra calcium (Experimental Biology meeting 2000). Both supplemental calcium and low-fat dairy proved effective. What's more, low-fat dairy's ability to burn fat and provoke fat loss have been confirmed in additional research (Obesity Research 4/04; 12:582-90).

    Fat cells contain calcium, and scientists believe that the more of this mineral a fat cell contains, the more fat will be burned off. This action is especially important when you cut back on calories, since that often gives your body the idea that it's starving, leading your metabolism to slow and making weight loss extremely difficult.

    A Complete Program

    To lose weight efficiently, stay in top shape and retain your feelings of energy, you also have to make sure you get enough of the vitamins and minerals necessary for good health.

    For those eating a high-protein diet who are limiting their fruits and vegetables, taking a supplement that incorporates nutrients from fruits and vegetables can help restore your feelings of well-being and help maintain your motivation for dieting and losing weight. (Supplements are available that deliver these nutrients without carbohydrates.)

    In addition, supplements of what are called ketogenic amino acids-the natural substances that form protein's building blocks-can also help fuel your weight-loss program. These special nutrients can be efficiently used for the body's energy needs, a process that helps you lose weight.

    And don't forget to keep moving! Soon you may have the kind of results researchers produced at the University of Pittsburgh when they studied women who exercised 40 minutes, five times a week (Journal of the American Medical Association 9/10/03). Those women lost 25 pounds in six months.

    Your results may be just as good or better!



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    Truth in Labeling
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    Date: June 14, 2005 10:44 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Truth in Labeling

    Truth in Labeling by Diane Stanton Energy Times, June 14, 2004

    Do you or don't you read food labels when you shop? If you don't, you're missing out on a prime source of information about your meals. If you want control of your health, focus on package labels and pick your foods carefully.

    The large print on food labels focus on what are called macronutrients: carbohydrates, fat and protein. Some of the smaller categories convey information about vitamins, fiber, and minerals, as well as the totals of fat and saturated fat contained in food. So, you have no excuse for claiming ignorance about your diet: the truth is in the labels.

    Food labels can be confusing to the uninitiated. Go into a big food store and you can be faced with what seems to be a forest of food information: more than 15,000 labels. Add to that fact that every year more than 30,000 new food products can be introduced to the marketplace, and what you're faced with is a jungle of food labels.

    That overwhelming wealth of food label information doesn't mean you should throw up your hands in dismay and give up reading and deciphering labels. You should arm yourself against that sea of labels with knowledge and, by understanding them, end your confusion and build your health.

    Label History

    A hundred years or so ago, food labels were only required to list the name of the food contained inside the package. The contents, quality and processes used to make the food were often a mystery. Little or no disclosure to consumers was made about how their food was created.

    By the early 1920s, the federal government, via the Food and Drug Administration (FDA), began requiring food companies to list the net weight of food on labels as well as the names and addresses of food processors and distributors. Finally, by the 1970s, listing basic nutritional information was mandated in a uniform way so that shoppers could have some basis for comparing foods. Then, in 1990, the Nutrition Labeling and Education Act made major alterations to the kinds of labels that had to be included on food packages.

    The FDA and the US Department of Agriculture (USDA) required significant changes to food labels that were supposed to make it easier for consumers to eat healthier diets. The labels requirements of 1994 included five major changes:

  • • The nutrition information on the label had to be printed in larger, more legible type.
  • • This condensed information had to be on the back or side of food packaging and titled as "Nutrition Facts." This type of information is also shown in grocery stores near the fresh food displays of fish, fruits and vegetables.
  • • The label had to include a column of information tagged as the "% Daily Value," designed to help consumers understand how the food could fit into a healthy diet.
  • • Each label had to include information about fat, cholesterol, fiber, sugar, calories from fat, and other information relevant to designing a healthy diet.
  • • The computed serving sizes were supposed to be more realistic and reflect the amount of food people actually eat at one sitting.

    Label Questions

    Consumer questions regarding food labels have led researchers to look into ways to help shoppers comprehend what food labels tell them. These studies are designed to help consumers match up their nutrition requirements with the foods they buy.

    For instance, at the University of Illinois at Urbana-Champaign, scientists have devised a label tool called See It, Do It, Teach It to help people improve their diets through comprehension of food label information. " One of the goals of the project was to help...teenaged girls and menopausal women understand how they can get the daily requirement for calcium into their diet in order to help prevent osteoporosis," says Karen Chapman-Novakofski, PhD, associate professor and nutritionist in the school's College of Agricultural, Consumer and Environmental Sciences.

    According to the See It, Do It, Teach It program, you should think of food labels as consisting of two sections:

  • • Food items you should limit: total fat, saturated fat, cholesterol, sodium and, if you're eating a low-carb diet, total carbohydrates
  • • What you may need to increase: vitamin A, vitamin C, calcium and iron

    " Much more attention has been paid to what people should limit rather than the nutrients needed. The average consumer doesn't know, for instance, how much vitamin A 10% of the Daily Value is, or how much calcium 25% of the Daily Value is," Dr. Chapman-Novakofski says.

    Upping Calcium Intake

    In their eight-week study of people's calcium consumption (Journal of Nutrition Education and Behavior 4/04), the University of Illinois research team found that people didn't know how much calcium was in the food they ate.

    After the initial part of the study, in which participants were shown how to look for calcium on labels, "the post-test revealed that the participants significantly increased their calcium intake to 821 mg per day, up from 372 mg per day," notes Dr. Chapman-Novakofski.

    " That's a lot closer to the daily requirements of 1,200 mg per day for men and women over 50, 1,000 mg for men and women aged 19 through 50 and 1,300 mg per day for [youths aged] 9 to [18] years," she adds.

    Parts of the Label

    The first item at the top of a nutrition food label tells you the portion size that the label measures. An important point to remember: these sizes are determined individually by each manufacturer. Consequently, all of the other values on the label are measured per portion.

    So, if you are comparing foods made by two different companies that employ very different portion sizes in their nutritional calculations, your label comParisons may be complicated.

    Another fact to be aware of: the listed portion size may be an odd division of the food within the container and not reflect a common-sense division. For instance, some food packages are labeled as containing 2.5 portions.

    And, to make things even more interesting, small boxes of candy that you might think contain barely enough for one helping may be labeled by the manufacturer as having two or more portions. As a result, if you eat the whole box, you often have to at least double the number of indicated calories, etc. to figure out the nutrients and calories you are consuming.

    The section of the label that notes calories, calories from fat and percent daily values is listed under the portion size. Here you are told how many calories you consume when you devour one portion and how many of those calories are derived from fat.

    This label focus on fat originated when consumers and dietitians were very concerned about Americans' fat consumption and hadn't yet switched their focus to carbohydrate consumption as a prevalent dietary health priority.

    Also included on the label: the daily value percentages aimed at showing you how much out of a total day's intake of various nutrients a portion bestows upon you.

    These percentage numbers are based on a theoretical analysis of a diet that contains 2,000 or 2,500 calories a day. (A notation at the bottom of the label tells you whether the calculation is based on 2,000 or 2,500.)

    Carb Facts

    If you've been eating a low-carb diet (or are planning this type of diet), the section of the label that lists carbohydrates may be especially useful. Under this heading, the label lists the totals for fiber and sugar.

    No matter what diet you are on, dietary fiber is desirable, since it represents indigestible carbohydrates that both pass through you without conveying any calories and keep beneficial bacteria in your digestive tract healthy.

    Most people want to limit their sugar totals, however, since this nutrient may raise your risk of being overweight and, when you eat a lot of it, may contribute to immune problems.

    Interestingly enough, when food chemists compute what is in food, they perform lab tests known as assays to distinguish its ingredients. (The manner in which these tests are performed are very strictly regulated by the FDA.)

    In fact, just about every nutrient listed on a food label is determined by laboratory test except for the carbohydrate content: the amount of water, fat, crude protein and ash are determined this way. But the total carbs are computed by simply subtracting the total of the other ingredients from the total amount of food, a kind of process of elimination.

    So while fat and protein are measured with precise lab tests, carbohydrate totals are figured by the leftovers. (The water and ash, by the way, are not usually listed on food labels.)

    Within the general carbohydrate group, are several categories of carbohydrates that produce very different effects in your body. These categories can be divided into sugar, sugar alcohols, dietary fiber and a collection of various chemicals that include organic acids, flavonoids, gums, lignans and others.

    According to the FDA, the food label only has to list the total carbs, sugar and dietary fiber. But some food companies now list things like sugar alcohols.

    Blood Sugar Effects

    Not all of these types of carbohydrates behave the same way in your body. For example, when your body digests table sugar, it turns immediately into blood sugar. So sugar and most other carbohydrate is what we call "digestible carbohydrate." Other carbs, such as sugar alcohol or glycerine, can be digested but do not turn to blood sugar. Still others, such as dietary fiber, are indigestible and pass through your body without impacting your blood sugar level.

    To date, the FDA has not focused on these important biochemical differences and treats all carbohydrates alike. This means that when you look at a food label, you do not see a number for the carbs that impact your blood sugar level. To do so, simply subtract the number of grams of fiber from the total number of carbohydrate grams.

    Net Carbs

    Recently, the phrases "low carb," "net carb" and "impact carbs" have begun to appear on food labels. These are not defined by the FDA; they were put on labels by by companies to help consumers pick out foods that are acceptable on low-carb diets. To arrive at the total of net carbs, food companies subtract the total amount of fiber and sugar alcohol from the total carbohydrates.

    Fiber Calculations

    Since the body cannot digest fiber, this nutrient (which is still important for good health) is not calculated into the total amount of carbohydrates. As for sugar alcohols, while-technically speaking-these are carbs and they do have calories, they have little effect on blood sugar and usually are not counted in total carbohydrates.

    According to the American Dietetic Association, people with diabetes who are managing their blood sugars using the carbohydrate counting method should "count half of the grams of sugar alcohol as carbohydrates since half of the sugar alcohol on average is digested.

    " Fiber is not digested, however. If the serving of food has more then 5 grams of fiber one should subtract the grams of fiber from the total carbohydrate grams." As you can see, when it comes to food, as in most things, knowledge is power. If you want power over your health, you need power over the food you eat. The road to that power is by reading food labels. What's in the food you're eating every day may surprise you.



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    Power Meals - Shakes, smoothies and bars help make getting good nutrition easy.
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    Date: June 14, 2005 08:28 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Power Meals - Shakes, smoothies and bars help make getting good nutrition easy.

    Power Meals

    by Phyllis D. Light, RH Energy Times, March 12, 2004

    Choices, choices, choices: For convenience, nutrition and either low-calorie or low-carb dieting, you now have an enviable range of choices. Shakes, smoothies and bars help make getting good nutrition easy.

    Whatever your inclination, drinks and bars offer a shortcut to daily nutrition without cooking. And whether you use them as meal replacements, diet aids or healthy snacks, these power meals fill you up without filling you out.

    That's the main reason these items have grown in popularity in natural food stores among the nutritionally knowledgeable searching for healthier alternatives to fast food.

    No matter how hectic your day, you have no excuses anymore for missing your daily required antioxidants and minerals. Either select a bar suited to your taste, or put your blender or food processor to work in creating drinks that use fresh fruits and veggies, yogurt, low-fat milk or ice and protein powders for maximum nutritional output.

    Quality note: always be sure to use organic foods for the best nutritional content, flavor and taste.

    Powerful Nutrition

    Prepared protein shake mixes and bars are ideal for losing weight, expanding personal energy or building muscle. Protein mixes are available in an assortment of flavors that are generally high in amino acids (protein building blocks) and low in carbohydrates. Of course if you are on a low-carb diet, forsake putting fruits and vegetables in your shakes; these items are too high in carbohydrates.

    What's more, bars not only provide a wealth of different tastes, but different bars are also tailored to different needs-whether you're seeking to lose weight, gain muscle or replace a meal, there's a bar out there just for you.

    If you use power shakes as meal replacements and you are on a low-carbohydrate diet, make sure the drink supplies plenty of protein and few carbohydrates. If you use either shakes or bars to replace one or more meals during the day, take a fiber supplement in addition. Fiber, which contains no calories, helps speed food through your digestive tract and may lower your risk of heart disease and cancer (Lancet 5/2/03).

    And remember: powders and bars should also be low in sugars and saturated fats. The weight-loss benefit: If you drink high-protein shakes or eat bars that taste good and leave you feeling satisfied, you'll have a better chance of sticking to your diet long enough to lose a significant amount of weight.

    Drink to Lose

    Research into weight loss has established protein shakes and bars as reliable diet aids. A study of 100 dieters between the age of 35 and 65 found that people who drank a daily soy protein shake lost more than 14 pounds each in three months (Eur J Clin Nutr 2003; 57:514). And in a study reported in the Journal of American Dietetic Association (3/01), folks who had a protein shake in place of one daily meal lost almost twice as much weight over 12 weeks than those who ate their regular food with the same amount of calories.

    Drinking your breakfast in the form of a protein shake can both increase your metabolism and help curb your appetite for the rest of the day.

    Researchers at Harvard University found that metabolism rose faster after eating a high-protein breakfast and that blood-sugar levels stayed high for about six hours after the meal (AHA Annual Conference on Cardiovascular Disease Epidemiology and and Prevention, 3/6/03). In comParison, when a sugary breakfast is consumed, blood-sugar levels rise quickly but fall rapidly, causing fatigue, tiredness and sleepiness.

    Protein shakes are especially effective when you are on a weight-loss plateau, trying to lose those last few tenacious pounds. (But shakes, smoothies and bars should not be your only meals of the day. Eat at least one low-calorie meal daily to supply nutrients that may not be in your shakes or bars.)

    Smoothie Operator

    Made with fruits and vegetables, smoothies are a tasty way of getting extra amounts of nutrients and soluble fiber. Using low-fat milk, yogurt, buttermilk or kefir, plus ice, creates a tempting and wholesome blend that lights up the taste buds. Powdered mixes can be used for added protein.

    Fruits and vegetables in your smoothies not only fill you up on relatively few calories, but they boost your energy and supply plenty of bioflavonoids (healthy, natural chemicals from plants), antioxidants, vitamins and minerals.

    The fiber in smoothies can help reduce cholesterol, relieve constipation and aid in the prevention of high blood pressure. For reduced calories and added heart health benefits, low-fat or no-fat milk products can be used in place of cream or regular milk in most recipes. For the best taste sensation, combine sour and sweet fruits together.

    Adding raw fruits and vegetables to smoothies provides natural enzymes that help with digestion and act as catalysts in hundreds of chemical reactions throughout the body. (You can also take enzymes in supplemental form.) Enzymes are not present in cooked foods since the heat of cooking destroys them.

    Nutrition for Kids

    If you have trouble getting your children to eat their fruits and vegetables, try giving them smoothies. Children can't resist these naturally sweet and healthy creations.

    According to Sally Fallon, author of Nourishing Traditions (New Trends Publishing), smoothies should be "high in quality, contain healthy fats, be naturally sweet, and contain fresh seasonal fruits and vegetables."

    Fallon also believes children should consume what are called lacto-fermented foods, including yogurt and kefir, which are aged to contain the kinds of friendly bacteria that normally live within our digestive tracts. For kids, Fallon also encourages the use of cream or cultured milk to ensure adequate fat and calcium, so important for the development of growing bodies.

    Smoothies are an interactive drink as far as children are concerned, since they love to help blend them. For extra nutrition power, add nutritional yeast, nut butters or ground flaxseeds. These supply additional vitamins and minerals, along with healthy fats. You can also add silken tofu to bump up the protein content. If your child is lactose intolerant, try mixing smoothies with rice milk, soy milk or juice.

    Bars Designed With A Woman's Needs in Mind

    The modern woman is a multitasking wonder, constantly juggling work and home responsibilities. So it's no wonder that bars aimed at women are among the most popular bars there are. Many women, in eyeing the bathroom scale, shortchange themselves of the nutrients they need. That's why a woman's bar needs to provide minerals like calcium, a bone-building necessity.

    Women also need to ensure that a bar contains enough of the B vitamins, particularly folate. This is especially true if a woman is pregnant, or wants to be: Folate is crucial in helping to prevent neural tube birth defects.

    Folate also teams up with two other B vitamins, B6 and B12, to control homocysteine. This protein metabolism byproduct, when present in excessive amounts, is associated with heart disease.

    Another popular ingredient in women's bars is soy, which has been duly recognized for its heart benefits. Studies also indicate that soy may help keep bones strong. (Not to mention the fact that the moisture soy holds helps make a bar's texture that much more appealing!)

    The Protein Game

    If you are unsure about how much protein you need each day, you are not alone. Are you getting too much, not enough, or just enough? Most people need between 45 and 60 grams of protein daily, and most protein shakes contain about 14 and 20 grams of protein per serving (check your labels). No matter what your nutritional needs are, you may find an answer in a smoothie, shake or bar. When it comes to power nutrition, tasting is believing!



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    Winter Survival Kit
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    Date: June 13, 2005 07:35 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Winter Survival Kit

    Winter Survival Kit by Joanne Gallo Energy Times, February 4, 2000

    Now that the flesh-baring season is but a distant memory, skin care may have dropped off your list of priorities. But unless you're planning on hibernating until May, Old Man Winter can play a cruel joke on your smooth, glowing complexion-causing cumulative damage not easily remedied. Defend yourself with our survival kit and keep the harsh elements from wreaking havoc on your outer sheath.

    Winter Blast

    Frigid temperatures and blustery winds take their toll on everyone's skin, whether it's normal, oily or dry. Cold dry air, combined with arid indoor heat, results in less natural sebum (oil) production. This oil acts as a protective barrier that helps hold moisture on the surface of the skin; hence less sebum leads to a rough and dry exterior. Icy winds can also cause redness as the stress induces tiny capillaries just underneath the skin's surface to burst.

    So the first order of business for winter skincare is preserving your skin's moisture. Along with external methods of bundling up all exposed areas, dietary habits can help preserve moisture internally.

    Skincare consultant Lynn J. Parentini, author of The Joy of Healthy Skin: A Lifetime Guide to Beautiful, Problem-Free Skin (Prentice Hall), suggests reducing your intake of coffee and tea, which act as diuretics; eating lots of fresh fruits and vegetables, which contain natural, vitamin-rich moisture; and increasing the amount of water you drink (those daily recommended eight glasses of water are even more important in winter).

    A Cleansing Experience

    Bathing can strip skin of its natural oils, so you should be careful of washing with overdrying soaps. Avoid deodorant soaps with harsh detergents which can irritate the skin, and look for milder soaps with moisturizers or a skin-softening shower gel. Neutrogena Rainbath Shower & Bath Gels gently cleanse and condition skin with a rich, full lather that won't leave a residue. Showers tend to be less drying than baths, but if you prefer soaking in a tub you can use bath oil to lubricate the skin. Also avoid very hot showers and baths as they can pull moisture out of the body.

    For extremely dry and sensitive skin, shower at night and follow with a rich moisturizer. Skin then can replenish its protective oils before the morning's icy blast.

    Skin Savers

    Now's the time to use a heavier cream moisturizer to counteract all these dehydrating forces, so finding the right one is imperative. In simpler times, choosing a body moisturizer came down to which one possessed the most pleasing smell. Today, lotions are formulated with nutrients and natural ingredients for powerful, soothing benefits. • CAMOCARE Soothing Cream contains patented Camillosan Camomile, a natural anti-inflammatory. This thick, therapeutic cream is great for dry patches on hands or elbows.

  • • Curel Ultra Protective Concentrated Antioxidant Moisturizer with SPF 15 features an exclusive "cationic technology" that delivers a high level of long-lasting hydration, as well as antioxidants like vitamin E to protect against environmental elements that can cause damage and premature aging.
  • • Nivea Creme, developed in 1911, reportedly smooths roughness even 12 hours after being applied. More than 98% of Nivea's ingredients are natural, and its Eucerit base resembles human sebum.

    Face the Season

    Faces need extra-special protection during winter, as moisturizers do double duty to fight the elements and aging. Many formulas contain alpha (AHA) and beta hydroxy acids: gentle exfoliants that slough off the top layer of dead skin cells to allow younger, smoother-looking skin to emerge. • Oil of Olay's Age Defying Series: Protective Renewal Lotion contains moisturizers, a beta-hydroxy complex, vitamin E and SPF 15. • Neutrogena Healthy Skin Face Lotion is formulated with alpha-hydroxy acids to ease lines, blotches and discoloration; vitamin A and pro-vitamin B5 to increase firmness and moisture levels; and antioxidant vitamins C and E to fight free radical damage and protect new skin.

    Sun Damage

    So you think the sun is the least of your problems in the winter? Better reflect on that matter again. The general public has finally warmed up to wearing sunblock in the summer, but year-round protection against ultraviolet (UV) rays is crucial to avoid premature aging.

    There are two types of UV rays, UVA and UVB: the former are responsible for aging and the latter for burning. Although UVB rays produce a more blatant sign of skin damage, it is limited to the epidermis, or outer layer of the skin.

    UVA rays, on the other hand, don't cause any discomfort, but they penetrate deep to the dermis or second layer of skin. Researchers at the University of Pennsylvania Department of Dermatology have shown that chronic exposure to sunlight can cause holes and breaks in the elastin and collagen fibers that give the skin its shape, definition and supple quality. This damage is what is known as "photoaging." Severely photoaged skin appears dry, scaly, leathery, spotted and deeply wrinkled.

    While the burning UVB rays are most intense during the summer months, UVA rays are prevalent year-round. Their effect on the skin is cumulative, so that the more you're exposed the more likely your skin is to age prematurely. And as only 14% of Americans wear sunscreen year-round (according to the American Academy of Dermatology), most of us are getting more UVA exposure than we realize.

    " New clinical evidence proves that sun damages the skin much faster than previously thought," notes Zoe Draelos, MD, clinical associate professor of dermatology at Wake Forest University School of Medicine. "It only takes small amounts of sun exposure, such as walking to the car or to the mailbox, to start skin damage."

    And for those who engage in popular winter sports like skiing, UVA rays are even stronger at higher elevations. Sunblocks with high SPFs (sun protection factor) guard against UVB rays but they do not block against UVAs, so many sunscreen products do not sufficiently protect against the entire range of UVA rays.

    It is crucial, then, to look for products that guard against the entire spectrum of UVA/UVB rays. Sunblocks that contain zinc oxide, titanium dioxide or Parsol 1789 provide complete protection against aging and burning rays. Try Coppertone Shade UVA Guard SPF 30, Hawaiian Tropic 30 Plus Broad Spectrum Sunblock, L'Oreal Ombrelle Sunscreen Lotion or Spray in SPF 15, or PreSun Ultra SPF 30.

    Lip Tips

    Don't forget that the lips are particularly susceptible to sun damage too. In comParison to other facial skin, they have far fewer oil glands, no sweat glands, a much thinner protective outer layer and very few melanocytes, the cells that produce the protective pigment melanin. Accumulated sun exposure makes the lips less plump as UV rays damage their collagen and elastin fibers, resulting in rough spots, scaly patches or faded areas.

    Even if you wear lipstick on a regular basis, most do not contain the sunscreens and conditioners you can find in a lip balm. Blistex offers a wide range of lip care products, like their new Blistex Herbal Answer, which contains the conditioning qualities of five natural, herbal extracts: aloe, chamomile, avocado, jojoba and shea butter, plus SPF 15; Blistex Ultra Protection with SPF 30 has six protectants for advanced defense against cold, wind and sun; Blistex DCT (Daily Conditioning Treatment) with SPF 20 contains aloe, lanolin, cocoa butter, and vitamins A and E to help keep lips soft and supple. o



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    Home on the Range
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    Date: June 13, 2005 03:52 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Home on the Range

    Home on the Range

    by Janis Jibrin, RD Energy Times, September 5, 1999

    Got chicken? Americans can't seem to get enough of this bird. Last year each of us ate, on average, just about 80 pounds of chicken, a whopping increase over the 49 pounds we each devoured in 1980 and an eight-pound increase from 1995. Part of this food's popularity comes from its lean image as a healthier, less fatty alternative to red meat (don't forget to take the fatty skin off). Chicken's also a cheap protein source: At many popular supermarkets you'll find weekly specials at about a dollar a pound.

    But at health food markets, chicken can cost upwards of $1.69 a pound. These birds may be touted as raised in an organic, stress-free environment and on a vegetarian diet, free of antibiotics. For many people, this poultry is a better buy.

    The Alternative Chicken

    Most of the supermarket chicken you pick up in grocery refrigerated cases are broilers, birds bred to mature in about eight weeks. In comParison, in the '60s, chickens needed 14 weeks to become adult poultry. Conventionally-raised broilers eat grain mixed with whatever's cheapest on the market, such as recycled cooking oil that's been used to fry fast foods and animal parts.

    These birds reside in chicken coops the size of football fields and don't see the light of day until transported to the slaughterhouse. On the other roost, alternatively raised chickens are brought up in a variety of ways (see box), but usually enjoy a more relaxed life and diet.

    Chickens on the farm receive antibiotics for two reasons: To fight off the diseases that can run rampant through a crowded chicken coop and to encourage faster growth.

    Antibiotics Stimulate Growth

    Mark Cook, PhD, professor of animal science at the University of Wisconsin at Madison, explains, "Gut bacteria trigger an immune system assault, which makes chickens a little feverish, suppresses appetite and slows growth. Antibiotics stimulate growth indirectly, by keeping bacteria levels down, and preventing the immune reaction." When birds get sick, they often get dosed with even more antibiotics.

    This widespread antibiotic use has come home to roost and may contribute to the growth of bacteria that, frequently exposed to chemicals, have evolved ways to keep from being killed by pharmaceuticals.

    This development threatens human health. Bacterial infections that people contract, once easily cured by penicillin or other drugs, are now tougher to eradicate. For instance, campylobactor, a common bacteria found in chicken, and responsible for some food poisonings, now demonstrates signs of resistance to drugs like floroquinolones. A powerful class of antibiotics, floroquinolones used to dependably conquer this infection.

    "Floroquinolones are an extremely important class of antibiotics, used to treat many types of infections such as urinary tract infection, a wide variety of gastrointestinal illnesses, pneumonia, almost everything," says Kirt Smith, DVM, PhD, epidemiologist, acute disease epidemiology section, Minnesota Department of Health.

    A study by Dr. Smith, published in the New England Journal of Medicine (340, 1999: 1525-32), showed that the percent of floroquinolone-resistant campylobactor appearing in infected people in his state-Minnesota-climbed from a little over 1% in infected people during 1992 to 10.2% in 1998. He and other scientists strongly suspect that the rise is a direct consequence of the Food and Drug Administration's (FDA) decision to allow floroquinolones in poultry feed beginning in 1995.

    Although it was nearly impossible for Dr. Smith to trace the precise origin of campylobactor poisoning, he believes chicken was usually the source-and not just U.S. chicken. Many of the infected people had returned from Mexico and other countries.

    "Sales of floroquinolones for poultry use in Mexico has increased dramatically," notes Dr. Smith.

    Many alternative chicken producers do not use any antibiotic-laced feed at all. Other farmers adjust the feed to lower gut pH, making it more acidic and lowering chances of bacteria. At the U. of Wisconsin, Dr. Cook is developing antibodies to suppress the immune response to bacteria so chickens won't need antibiotics to spur growth. Buying and dining on chicken raised with little or no antibiotics could beneficially lower your risk of contracting a hardy bacterial infection. Better to catch campylobactor from an antibiotic-free chicken than a conventional chicken, speculates Dr. Cook. "There's less likelihood the bug will be resistant, and a better chance your problem can be cured with antibiotics," he explains.

    And, looking beyond your own immediate health risk, buying antibiotic-free chicken makes a small contribution to stopping the spread of antibiotic resistant bugs. A Matter of Taste Conventionally raised chickens get little exercise and live only eight weeks, so they're tender but bland.

    "There's not much taste in a modern chicken. Free range or organically grown, older birds usually have more taste," notes Dr. Cook.

    The days of barnyard chickens happily clucking and strutting around in picturesque nature have disappeared with the family farm. Today, chickens lead a meager existence. After hatching, baby chicks are tossed into a gigantic hen house that is home to up to 30,000 birds. Their short lives are lived within the United States Department of Agriculture (USDA) mandated 3/4 square foot per chicken. In that squeeze, birds can catch "chicken influenza," especially in winter when it's too cold to let in much fresh air.

    Laying hens don't experience much more of a peaceful existence. These birds live their years with about five other hens, so crowded they can't flap their wings. Cages, suspended in the air, let eggs roll into a holding area. So they don't peck each other, hens are often debeaked, a painful process that can cause infection.

    Hens go through natural laying and "dry" cycles. Growers manipulate this cycle by "forced molting," depriving hens of food for four to 14 days to keep them constantly laying. By the end of two years, hens are worn out. Their inactivity weakens their bones enough that electrical stunning, the usual method for knocking chickens out before slaughter, shatters their bones. So some wind up being plucked and boiled alive, according to Mary Finelli, program director for farm animals and public health at the Humane Society of the United States. The meat from these hens, tougher than other birds, was probably in your deli lunch sandwich. It's also used in the school lunch program or may end up in dog food.

    "Generally, organically-grown broilers and hens have it better because room to move is part of the organic certification process," says Finelli. Finelli suggests visiting chicken suppliers to find out how chickens are treated. Or, she advocates a Humane Society book listing reliable firms. For a local producer call the society: 202-452-1100. According to a Consumer Report report, some growers force chickens out the last week of their lives to brand them "free range." So free range isn't a prime standard for choosing a decently raised chicken. However, turkeys thrive outdoors, so choosing free-range turkey is often a good idea for better tasting poultry.

    In any case, organic is your best bet for chicken without pesticides. Make it your main choice for your 80 pound yearly consumption!

    To fight cruel treatment of poultry:

    • Forced Molting Ban. Forced molting is shocking hens for more eggs. To support petitions banning forced molting write: Docket Manage-ment Branch, FDA, Dept. Health & Human Serv-ices, 12420 Parklawn Drive, Room 1-23, Rock-ville, MD 20857. Include docket # 98P-0203/CP

    • Downed Animal Protection Bill (House Bill 443, Senate Bill S515) spares some animals from the tortuous journey from chicken house to slaughterhouse. Mandates humane euthanization.



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    ACTIVATED QUERCETIN: a truly hypoallergenic formula...
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    Date: May 31, 2005 04:45 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: ACTIVATED QUERCETIN: a truly hypoallergenic formula...

    Most of us like to stroll through the countryside. Or play with our pets. Or eat our favorite foods. Or just stop and smell the beautiful flowers. But when our bodily systems are at odds with the natural world, these simple pleasures can be difficult to enjoy. That’s why the nutrition experts at Source Naturals created ACTIVATED QUERCETIN: a truly hypoallergenic formula developed so we all can enjoy the pleasures of nature.

    Quercetin: A Unique Bioflavonoid Quercetin is a unique bioflavonoid that has been extensively studied by researchers over the past 30 years. Bioflavonoids - first discovered by Nobel Prize Laureate Albert Szent-Györgyi in the 1930’s - occur as pigments in plants, where they usually are found in close association with vitamin C. Together, bioflavonoids and vitamin C provide antioxidant protection, helping plants withstand harsh variations in wind, rainfall, temperature, and sunlight. Bioflavonoids also can be important to our optimal health - but they cannot be manufactured by our bodies.

    Quercetin is no stranger to the human diet: for example, onions may contain up to 6% quercetin (dry weight). As a food supplement, quercetin is hypoallergenic, containing no citrus, wheat, corn, or other common allergens.

    Histamine and Leukotriene Inhibition: Helping Us Enjoy the Natural World

    Quercetin has a strong affinity for mast cells, the body’s main storage unit for histamines. Like many other bioflavonoids, it has the ability to stabilize cell membranes, preventing histamines from spilling out of mast cells into the bloodstream and surrounding tissues. Also, quercetin helps inhibit the action of two enzymes - phospholipase A2 and lipoxygenase - which act on arachidonic acid (a key fatty acid constituent of many cell membranes) to create leukotrienes. By inhibiting the release of histamines and leukotrienes into our bloodstreams, quercetin can leave us free to enjoy the natural world.

    Activated for Absorption

    Quercetin’s main disadvantage is that it is barely soluble in water, and therefore difficult for the body to absorb. Without biochemical help, its beneficial properties may be of very limited use to our bodies. There are lots of quercetin products on the market, but they won’t do much good if the quercetin is not activated for use by the body. Source Naturals combines its quercetin with bromelain, an enzyme derived from pineapple that is known to increase the body’s ability to absorb various substances. Bromelain also is known to have many of the same histamineand leukotriene-inhibiting properties as quercetin, so they enhance each others’ performance. Source Naturals ACTIVATED QUERCETIN contains vitamin C in a non-acidic form, magnesium ascorbate. Studies suggest that vitamin C has a synergistic relationship with quercetin, which improves quercetin’s use by the body. Since the acidic form of vitamin C (ascorbic acid) can create mild stomach irritation, and since quercetin is best taken on an empty stomach to maximize absorption, a pH-buffered form of vitamin C such as magnesium ascorbate is preferable.

    Combined Excellence

    Source Naturals ACTIVATED QUERCETIN is a state-of-the-art quercetin complex. With 333 mg of quercetin in each tablet, and key additional ingredients to maximize quercetin’s absorption and beneficial properties, ACTIVATED QUERCETIN is a potent formula. It gives you more help - so you can enjoy nature again. Source Naturals ACTIVATED QUERCETIN is available in 50, 100 and 200-tablet bottles.

    References

    • Busse, W.W., Kopp, D.E., and Middleton, E. (1984). “Flavonoid modulation of human neutrophil function.” Journal of Allergy and Clinical Immunology, 73: 801-809. • Middleton, E. (1981). “Quercetin: an inhibitor of antigen-induced human basophil histamine release.” Journal of Immunology, 127: 546-550. • Pearce, F., Befus, A.D., and Bienenstock, J. (1984). “Mucosal mast cells: III. Effect of Quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.” Journal of Allergy and Clinical Immunology, 73: 819-823. • Tarayre, J.P. and Lauressergues, H., (1977). “Advantages of combination of proteolytic enzymes, flavonoids, and ascorbic acid in comParison with non-steroid anti-inflammatory drugs.” Arzneimforsch. 27: 1144-1149.



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    Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...
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    Date: May 24, 2005 09:52 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...

    Cognitive Improvement in Mild to Moderate Alzheimer's Dementia After Treatment with the Acetylcholine Precursor Choline Alfoscerate: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Maria De Jesus Moreno Moreno, MD Instituto Nacional de la Senectud, Mexico City, Mexico


    This study assessed the efficacy and tolerability of the cholinergic precursor choline alfoscerate (CA) in the treatment of cognitive impairment due to mild to moderate AD (Alzheimer's disease).

    in both men and woman they consistently improved after 90 and 180 days versus baseline with adiministration of GPC three times a day, whereas in the placebo group they remained unchanged or worsened. Statistically significant differences were observed between treatments after 90 and 180 days.

    Keypoints:

  • improved cognition and global function
  • showed a statistically significant improvement after 90 and 180 days of treatment
  • Increased neurotransmission
  • With out treatment men and woman declined consistantly
  • references:

    Bartus RT, Dean RL III, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction, Science. 1982;217:408-414. 2. Larson EB, Kukull WA, Katzman RL. Cognitive impairment: Dementia and Alzheimer's disease. Annu Rev Public Health. 1992;13:431-449. 3. Hofman A, Rocca WA, Brayne C, et al, for the European Prevalence Research Group. The prevalence of dementia in Europe: A collaborative study of 1980-1990 findings. Int d Epidemiol. 1991;20:736-748. 4. Blackwood W, Corsellis JAN, eds. Greenfield's Neuropathology. 3rd ed. London: Arnold; 1976. 5. Geldmacher DS. Cost-effective recognition and diagnosis of dementia. 5emin Neurol. 2002;22:63-70. 6. Perry EK, Tomlinson BE, Blessed G, et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ. 1978;2:1457-1459. 7. Perry EK. The cholinergic hypothesis--ten years on. Br Med Bull. 1986;42:63-69. 8. Giacobini E. From molecular structure to Alzheimer therapy. Jpn d Pharmacol. 1997;74:225-241. 9. Giacobini E. Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: From tacrine to future applications. Neurochem Int. 1998;32:413-419. 10. Brinkman SD, Smith RC, Meyer JS, et al. Lecithin and memory training in suspected Alzheimer's disease. J Gerontol. 1982;37:4-9. 11. Davis E, Emmerling MR, Jaen JC, et al. Therapeutic intervention in dementia. Crit Rev Neurobiol. 1993;7:41-83. 12. Amenta E Parnetti L, Gallai V, Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropiate approaches? Mech Ageing Dev. 2001;122:2025-2040. 13. Sigala S, Imperato A, Rizzonelli P, et al. k-Alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat. Eurd Pharmacol. 1992;211:351-358. 14. Govoni S, Battaini E Lucchi L, et al. Effects of alpha-glycerylphosphorylcholine in counteracting drug-induced amnesia: Through cholinergic and non-cholinergic mechanisms [in Italian]. Basi Raz Ter. 1991;21:75-78. 15. Canonico PL, Nicoletti F, Scapagnini U. Neurochemical and behavioral effects of alpha-glycerylphosphorylcholine [in Italian]. Basi Raz Te~ 1990;20: 53-54. 191 CLINICAL THERAPEUTICS ® 16. Parnetti L, Amenta E Gallai V. Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: An analysis of published clinical data. Mech Ageing Dev. 2001;122:2041-2055. 17. Venn RD. The Sandoz Clinical Assessment-Geriatric (SCAG) scale. A general-purpose psychogeriatric rating scale. Gerontology. 1983;29:185-198. 18. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991;19:330-341. 19. Frattola L, Piolti R, Bassi S, et al. Multicenter clinical comParison of the effects of choline alphoscerate and cytidine diphosphocholine in the treatment of multi-infarct dementia. Curt Ther Res Clin Exp. 1991;49:683-693. 20. Muratorio A, Bonuccelli U, Nuti A, et al. A neurotropic approach to the treatment of multi-infarct dementia using L-c~-glycerylphosphorylcholine. Curt Ther Res Clin Exp. 1992;52:741-75l. 21. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: APA; 1994. 22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. 23. Folstein ME Folstein SE. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198. 24. Loeb C, Gandolfo C. Diagnostic evaluation of degenerative and vascular dementia. Stroke. 1983;14:399-401. 25. Hamilton M. A rating scale for depression.J Neurol Neurosurg Psychiatry. 1960;23:56-62. 26. Hamilton M. Development of a rating scale for primary depressive illness. BrJ Soc Clin Psych& 1967;6:278-296. 27. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. AmJ Psychiatry. 1984;141:1356-1364. 28. Reisberg B, Ferris SH, De Leon MJ, et al. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry. 1982;139:1136-1139. 29. National Institute of Mental Health. Clinical global impressions. In: Guy W, ed. ECDEU Assessment for Psychopharmacology. Revised edition. Rockville, Md: National Institute of Mental Health; 1976:217-222. 30. Burns A, Russell E, Page S. New drugs for Alzheimer's disease. Br J Psychiatry. 1999;174:476-479. 31. Kumar V, Anand R, Messina J, et al. An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors. Eur J Neurol. 2000;7:159-169. 32. Knapp MJ, Knopman DS, Solomon PR, et al, for the Tacrine Study Group. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991. 192 M. Moreno 33. Lindstrom MJ, Bates DM. Newton-Rapshon algorithms for linear-mixed effects models for repeated measure data. J Am Stat Assoc. 1998;83:1014-1022. 34. Thai LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology 1996;47:705-711. 35. Rogers SL, Friedhoff LT, for the Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia. 1996;7:293-303. 36. Rogers SL, Doody RS, Mohs RC, Friedhoff LT, for the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Arch Intern Med. 1998; 158:1021-1031. 37. Corey-Bloom J, Anand R, Veach J, for the ENA 713 B352 Study Group. A randomized trial evaluating the efficacy and the safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998;1:55-65. 38. Rosler M, Anand R, Cicin-Sain A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. BMJ. 1999;318: 633-638. 39. Amenta E Bronzetti E, Del Valle M, Vega JA. Effects of alpha-glycerylphosphorylcholine in neuroanatomy of aging brain in experimental animals [in Italian]. Basi Raz Te~: 1990;20:31-38. Address correspondence to: Scientific Department, Italfarmaco SpA, via dei Lavoratori 54, 20092 Cinisello Balsamo, Milan, Italy.

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    L-Tryptophan 500mg
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    Date: May 13, 2005 06:45 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: L-Tryptophan 500mg

    L-5-Hydroxytryptophan treatment of sleep terrors in children.

    Bruni O, Ferri R, Miano S, Verrillo E.

    Centre for Paediatric Sleep Disorders, Department of Developmental Neurology and Psychiatry, University of Rome "La Sapienza", Via dei Sabelli 108, 00185 Rome, Italy. oliviero.bruni@uniroma1.it

    To test the hypothesis that the administration of L -5-hydroxytryptophan (L -5-HTP) might exert beneficial effects on sleep terrors, we carried out an open pharmacological trial in a group of children with sleep terrors compared to a group of children with the same disorder but without L -5-HTP treatment. Participants in the trial were 45 children (34 males and 11 females; age range 3.2-10.6 years), referred to the Sleep Centre of the Department of Developmental Neurology and Psychiatry of the University of Rome "La Sapienza", affected by sleep terrors. All subjects underwent: (1) complete medical and sleep history; (2) complete neurological examination and EEG recording whilst awake and sleeping, (3) a structured sleep diary for 2 months, (4) after 1 month, all subjects were examined again from the clinical and EEG points of view and (5) after 6 months, a structured interview in order to evaluate the clinical outcome. After the first visit, L -5-HTP was administered (2 mg/kg per day) at bedtime to 31 randomly selected patients for a single period of 20 consecutive days. After 1 month of treatment, 29/31 (93.5%) of patients showed a positive response. In the comParison group without drug therapy, after 1 month, the episodes disappeared only in four children (28.6%) while ten children (71.4%) showed the persistence of episodes with the same frequency as before. After 6 months, 26/31 (83.9%) of children treated with L -5HTP were sleep terror-free, while in five children (16.1%) sleep terror episodes persisted. Of the children in the comParison group, ten (71.4%) continued to show sleep terrors at 6-month follow-up. CONCLUSION:to our knowledge, this is the first study demonstrating the efficacy of a new drug treatment for sleep terrors. These results confirm our initial hypothesis and represent evidence that treatment with L -5-hydroxytryptophan is able to modulate the arousal level in children and to induce a long-term improvement of sleep terrors. Copyright 2004 Springer-Verlag

    Publication Types:

  • Clinical Trial
  • Randomized Controlled Trial


  • L-Tryptophan 500mg 90ct


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    Garlic Extract Modulation or Pulmonary Vascular Function:
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    Date: May 12, 2005 12:41 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Garlic Extract Modulation or Pulmonary Vascular Function:

    Garlic Extract Modulation or Pulmonary Vascular Function: ComParisons Among Fresh, Aged, Freeze-dried Powder and Oil Macerate

    Author:
    Ku DD, Abdel-Razek TT, Dai J, Fallon MB, Abrams GA

    Source:
    FASEB Journal, 1998

    Abstract:
    Garlic has been advocated for a variety of therapeutic applications including pulmonary vasodiladon, but definitive experimental evidence supporting these claims remain inconclusive. We compared the relative vasorelaxation efficacv of fresh garlic extract (FG) to those commercially packaged garlics on rat pulmonary artery (PA) rings. Water extract of fresh whole garlic (1-500 µg/ml) produced a dose-dependent relaxation in endothelium (EC)-intact (PA, reaching a maximum of -62±4% (M±SE of 18 rings). Maximum relaxation observed with the garlic storage leaves (-79.±4%, n=16 rings) was significantly higher than the garlic inner stem (-48±5%, n=12 rings). Boiling of garlic extracts at l00ºC for 30 mins reduced the relaxation by 10-20%. Mechanical disruption of EC or pretreatment with L-NAME, reduced the relaxation by 30-40%. Extracts from freeze-dried powder (Garliquc; Pure-Gar and Kwai), aged garlic (Garlique), and garlic oil macerate (Softgel) resulted in -87±3% (n=16 rings), -72±6% (n=30 rings), -45±3% (n=30 rings), -22±5% (n=14 rings) and -5±3% (n=14 rings relaxation, respectively. Vasoinhibitory effect of FG extract was readily reversible upon washing, whereas the Pure-Gar and Garlique effects tended to be longer lasting and PA contractile response remained depressed even after 60-min washing. These results show that extracts of both fresh and freeze-dried garlic, but not the oil macerate, are capable eliciting both EC-dependent and -independent relaxation in rat PA. Differences in vasorelaxant potency may be related to the concentrations of the garlic active ingredient, allicin, in different garlic preparations.


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    Nattokinase: Food For Cardiovascular Health
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    Date: May 10, 2005 10:13 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Nattokinase: Food For Cardiovascular Health

    Say it Ain't Soy!

    Yes, but this soybean is different! What makes it different is simple. after hours of fermentation, the boiled soybean metamorphose to an ancient medicinal food called "Natto" pronounced "Nah'-Toe." Natto may just be the "perfect food," producing 18 valuable amino acids and an enxyme natokinase that may challenge the pharmaceutical industry's best "blood-clot busters." Natto, which has recently attracted attention throughout the world, is the third most popular type of fermented soybean in the japanese diet. Japan has the highest average longevity in the world, which may partly be attributed to a high consumption of natto.

    When compared with ordinary soybeans, the natto produces more calories, protein, fiber, calium, potassium and vitamin B2. Its high protein and economical price in terms of protein per gram has earned it the sobriquet. "Hata-ke no niko," a meat of the field. This nickname appears well deserved, as in comParison with an equivalent amount of beef, natto has slighly less protein (16.5 grams to 21.2 grams),but contains more carbohydrates and fiber, and is also higher in calcium, phosphorous, iron and vitamin B2. Plus, it has nearly double the calcium and far more vitamin E to boot.

    According to legend, the first person to originate traditional Japanese natto was the famous warrior Yoshiie Minamoto during the Heian era of Japanese history (794 - 1192 A.D.). The horse was extremely important to the Japanese samurai warrior of the period, and great care was given to provide suitable provisions for the horses when armies were on the move. Typically, boiled soybeans were cooled down, dried in teh sun and packed immediately in rice straw bags for transport with the army. If the army was on a rapid deployment, the boiled soybeans were packed hastely into the rice straw bags with out cooling or drying. The rice straw just happened to contain a harmless and naturally occuring microorganism, Bacillus Subtilis that fermented the soybeans and producted natto with its characteristic sticky texture.

    Initially, the soybeans were presumed to have spoiled until yashiie minamoto observed that his horses were "picky eaters" and demonstrated a preference for the "spoiled" Soybeans or natto. One day, Minamoto demonstrated tremendous courage and dipped his fingers into the seemingly rotten goo. To his astonishment, the fermented soybeans were not only edible but had a distinct umami flavor. Minamoto was responsible for introducing natto to northwestern Japan, where he ruled. To this day natto is especially popular in that region of Japan as a folk remedy for fatigue, beriberi, dysentery, heart and vascular deseases.

    The most distinctive features of natto are the adheasive surrounding the soybeans and the strong flavor. The sticky material has been shown to consist of poly-g-glutamic Acid (D and L) and polysaccharides (Levan-form fructan), and the strong "cheese like" flavor is due to the presence of pyrazine. These features sometimes make it hard for some people, especially people from other countries, to accept natto; however, these are the main factors which give natto the outstanding properties. Natto, which has recently attracted attention throughout the world, is a familiar part of the Japanese diet.

    Technical Aspects of Nattokinase:

    Nattokinase produces a prolonged action in two ways: it prevents the formation of thrombi and it dissolves existing thrombus. Nattokinase orally administrated to twelve healthy adults indicated elevations in the breakdown products of the fibrin and the ability of the blood to break down fibrin called eugobulin fibrionlytic activity (EFA). These results suggest the ability of nattokinase to accelerate fibrinolysis in the blood for a prolonged period of time. FDP levels in the adults drastically increased 4 hours after the administration of the nattokinase, indicating that fibrin within the blood vessels is gradually being disolved with repeated intake of nattokinase. By measuring the EFA & FDP levels, the activity of nattokinase has been determined to last for 8 to 12 hours. An additional parameter for confirming the action of NATTOKINASE following oral administration is a rise in blood levels of tissue plasminogen activator (TPA) antigen, which indicates a release of TPA from the endothelial cells and/or the liver and the endogenous production of plasmin (The body's blood clotting buster).6,7

    In 1995, researchers from Miyazki Medical College and Kurashiki Unerversity of science and arts in Japan studied the effects of nattokinase on the blood preasure in both animals and human subjects. In addition, the researchers confirmed the presence of inhibitors of angiotensin converting enzyme (ACE) within the test extract, which consisted of 80% ethanol extract of lyophilized viscous materials of natto. ACE causes blood vessels to narrow and blood pressure to rise - by inhibiting ACE; nattokinase has a lowering effect on blood pressure.1,2

    The same natto extract was then tested on human volunteers with high blood pressure. Blood pressure levels were measured after 30 grams of lyophilized extract (Equivalent to 200 grams of natto food) was administered orally for 4 consecutive days. In 4 out of 5 volunteers, the systolic blood pressure (SBP) decreased on average from 173.8+- 20.5 mmHg to 154.8+-12.6 mmHg. Diastolic blood pressure (DBP) decreased on average from 101.0+- 11.3 mmHg to 91.2+- 6.6 mmHg. On average, this data representes a 10.9 percent drop in SBP and a 9.7 precent drop in DBP. 1,2,6

    Disclaimer: The above artical is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competen t licensed professional health care provider. The information in this artical has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any desease.

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