Search Term: " progression "

	High Fiber Diet May Reduce Risk of Dementia	Darrell Miller	4/29/22
	The Kidneys and Your Health: Everything You Need to Know	Darrell Miller	4/29/22
	Delta-8 THC Shows Promise in Combating Myocarditis	Darrell Miller	4/29/22
	Oolong tea inhibits the growth and progression of breast cancer cells	Darrell Miller	5/8/19
	Camu camu fruits are rich in an anthocyanin that stops tumors fromgrowing	VitaNet, LLC Staff	1/16/19
	Study: PQQ (pyrroloquinoline quinone) may prevent and even reverseAlzheimer's	Darrell Miller	1/4/19
	The evidence is clear: Hemp slows the progression of ovarian cancer	Darrell Miller	7/12/18
	Smoking marijuana found to have the same weakening effect on the blood vessels as cigarettes	Darrell Miller	4/24/18
	Osteoporosis And What You Should Know About Bone Health	Darrell Miller	3/17/18
	The Surprising Anti-Aging Benefits of Fiber	Darrell Miller	2/19/18
	Could CBD oil be used for bone disorders ?	Darrell Miller	9/28/17
	Chaga Mushroom: 5 Health Benefits of This Ancient Medicine	Darrell Miller	7/9/17
	4 Ways You're Eating Your Way Toward an Anti-Inflammatory Diet	Darrell Miller	5/6/17
	Omega 3 Fatty Acid Found To Stop Liver Damage From Getting Worse	Darrell Miller	4/27/17
	How Does Cannabis Affect Your Memory Over Time?	Darrell Miller	4/21/17
	Eating anti-inflammatory foods may reduce symptoms of rheumatoid arthritis	Darrell Miller	3/22/17
	Vitamin C effective in targeting cancer stem cells	Darrell Miller	3/12/17
	Curcumin helps to effectively ease inflammatory bowel disease: China mouse study	Darrell Miller	2/21/17
	Mushrooms 'can reduce dementia' by boosting nerves in the brain	Darrell Miller	1/31/17
	11 best essential oils for arthritis: Control arthritis and inflammation	Darrell Miller	1/23/17
	How Oxidative Stress Affects Multiple Sclerosis	Darrell Miller	12/25/16
	Boswellia Reduces 5-LOX Activity	Darrell Miller	12/9/16
	High-dose vitamin C reduces inflammation in cancer patients, study shows	Darrell Miller	12/7/16
	Microbes in your gut influence age-related macular degeneration	Darrell Miller	11/29/16
	Low vitamin D levels linked to Parkinson's and Alzheimer's disease	Darrell Miller	10/30/16
	What Are Glycosaminoglycans (GAGs) And What Herbs Contain Them?	Darrell Miller	7/21/15
	Ginkgo Biloba A Modular Solution To Boosting Memory.	Darrell Miller	8/4/14
	Does Bilberry Have Healing Properties?	Darrell Miller	3/28/14
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	Third- The Science (Putting It All Together) Boswellia & Inflammation	Darrell Miller	4/3/08
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	Fighting fat with fat makes sense with conjugated linoleic acid.	Darrell Miller	4/3/06
	Glucosamine & Chondroitin - JOINT HEALTH	Darrell Miller	12/22/05
	Vitaberry Plus + Super Fruit Antioxidant	Darrell Miller	12/7/05
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	Re: Its in the Blood	Darrell Miller	5/9/05

Date: April 29, 2022 03:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: High Fiber Diet May Reduce Risk of Dementia

A high fiber diet may reduce the risk of developing dementia, according to a study published in the journal Neurology. The study found that people who ate the most fiber were 30% less likely to develop dementia than those who ate the least fiber. This is an important discovery, as dementia is becoming increasingly common around the world. There are currently about 47 million people living with dementia, and this number is expected to grow to 135 million by 2050.

What is dementia and what are the symptoms?

Dementia is a general term for a decline in mental ability due to disease or injury. symptoms can vary greatly from person to person, but may include problems with memory, mood, and thinking. People with dementia may have difficulty remembering recent events or familiar faces, and they may become confused about time and place. They may also have trouble completing familiar tasks, such as cooking a meal or getting dressed. As the disease progresses, people with dementia may lose the ability to communicate or take care of themselves. Dementia is not a normal part of aging, and it can affect people of all ages. There is no one test that can diagnose dementia, and doctors often use a combination of medical tests, brain scans, and neurological exams to make a diagnosis. There is no cure for dementia, but there are treatments that can help people manage the symptoms and improve their quality of life.

What causes dementia?

Dementia is a complex neurological disorder with no known underlying cause. While some theories suggest that environmental factors such as exposure to certain toxins or injuries may play a role, the exact mechanisms underlying dementia remain uncertain. Some researchers have proposed that dementia may be related to problems in the functioning of certain proteins in the brain, while others have suggested that chronic inflammation may also be involved. However, there is still much work to be done in terms of understanding the biological mechanisms underlying this debilitating and often devastating illness. Ultimately, identifying the precise causes of dementia will help inform more targeted and effective treatments for this disease, allowing those affected by it to live fuller and healthier lives.

How can a high fiber diet reduce the risk of developing dementia?

A diet rich in fiber has been linked with a reduced risk of developing dementia. Fiber is a type of carbohydrate that the body cannot digest, and it is found in plant-based foods such as fruits, vegetables, and whole grains. Foods high in fiber are known to promote gut health, and some studies have suggested that gut inflammation may play a role in the development of dementia. In addition, fiber-rich foods tend to be high in antioxidants and other nutrients that have been linked with brain health. For these reasons, increasing your intake of fiber-rich foods may help to reduce your risk of developing dementia.

What are some good sources of fiber?

There are many good sources of fiber, including both plant-based and animal-based foods. Psyllium husk, which is made from the soluble fibers found in the seeds of a Mediterranean shrub called Plantago ovata, is a popular option due to its high concentration of dietary fiber and other nutrients. Inulin, meanwhile, is a type of carbohydrate that is naturally found in many fruits, vegetables, and legumes. Both psyllium husk and inulin are excellent sources of nutrition that can help promote good digestive health and overall well-being. Other common sources of dietary fiber include whole grains like oats and barley, as well as beans, lentils, nuts, and seeds. Whether you are looking for plant-based or animal-based sources of fiber, there are plenty of options out there to suit your needs.

How much fiber should you eat each day?

There is no single answer to the question of how much fiber you should eat each day. The amount of fiber that your body needs will depend on a number of factors, including your age, sex, and overall health status. In general, most health experts recommend consuming between 25 and 35 grams of fiber per day. This can typically be achieved by eating a balanced diet that includes a variety of fiber-rich foods, including fruits, vegetables, nuts, seeds, whole grains, and legumes. Furthermore, it is important to remember that fiber needs can vary depending on your symptoms or underlying condition. So if you are experiencing any gastrointestinal issues or other health concerns, it is best to consult with your doctor to determine the right amount of dietary fiber for your body.

Are there any risks associated with eating a high fiber diet?

While fiber is an essential part of a healthy diet, it is important to be aware of the potential risks associated with eating too much fiber. Fiber is a type of carbohydrate that the body cannot digest, and it is typically found in plant-based foods such as fruits, vegetables, and whole grains. When fiber is not broken down by the body, it can bind to other nutrients and substances in the digestive tract and cause them to be eliminated from the body before they are absorbed. This can lead to nutrient deficiencies and other health problems. In addition, consuming large amounts of fiber can also cause bloating and gas.

How can you prevent dementia from developing?

There is no one definitive cause of dementia, but there are a number of risk factors that have been identified as contributing to its development. These can include things like a genetic predisposition, lifestyle factors like drinking and smoking, and certain health conditions. Because these risk factors can vary widely from person to person, there is no one strategy that will prevent dementia in everyone. However, there are some general measures that anyone can take to lower their risk of developing dementia. These might include maintaining healthy eating habits, staying physically active, and avoiding excessive exposure to environmental toxins. Additionally, early diagnosis and treatment for any existing health conditions can also play an important role in reducing the likelihood of dementia. By taking these proactive steps, it is possible to greatly reduce your risk of developing this debilitating condition.

Vitamins and Dementia

Some studies have suggested that certain vitamins may help to prevent dementia. Vitamin B6, B12, and folic acid are involved in the metabolism of homocysteine, a substance that has been linked to an increased risk of Alzheimer's disease. Vitamin E is an antioxidant that helps to protect cells from damage, and it has been suggested that this may help to slow the progression of dementia.

Fruits and vegetables can help the body combat dementia

Recent studies have suggested that diet may also play a role in the development of dementia. In particular, fruits and vegetables appear to offer some protection against the disease. The antioxidants found in these foods help to fight inflammation and damage to cells, both of which are thought to contribute to the development of dementia. In addition, fruits and vegetables are a good source of vitamins and minerals, which are essential for brain health. Thus, incorporating more fruits and vegetables into your diet may help to reduce your risk of developing dementia.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6400)

Date: April 29, 2022 03:10 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Kidneys and Your Health: Everything You Need to Know

The kidneys are two bean-shaped organs that sit in the lower back, on either side of the spine. They play a vital role in your health, filtering toxins from the blood and regulating fluid balance in the body. We will discuss everything you need to know about the kidneys, including common kidney problems and how to keep them healthy!

What are the common kidney problems

The kidneys are a pair of organs that filter waste products from the blood and excrete them in urine. They are also responsible for regulating fluid and electrolyte balance in the body. Kidney problems can range from mild to severe, and can be acute or chronic. Common kidney problems include kidney stones, urinary tract infections, and Nephrotic Syndrome. Kidney stones are small, hard deposits that form in the kidney when there is an imbalance of minerals in the urine. Urinary tract infections occur when bacteria enter the urinary system and multiply. Nephrotic Syndrome is a kidney disorder that causes the body to excrete large amounts of protein in the urine.Kidney problems can often be treated with medication, but in some cases, surgery may be necessary. Early diagnosis and treatment is important to prevent serious complications.

Acute renal failure

Acute renal failure is a sudden onset of kidney failure that can be life-threatening. The kidneys are responsible for filtering waste from the blood and balancing fluids in the body. When they are not working properly, waste can build up in the blood and cause serious health problems. Acute renal failure can be caused by a number of factors, including dehydration, infection, and certain medications. Symptoms include decreased urine output, swelling, fatigue, and confusion. If left untreated, acute renal failure can lead to coma and death. Early diagnosis and treatment is essential for a successful outcome.

Chronic renal failure

Chronic renal failure, or CRF, is a serious medical condition that affects the kidneys. In this condition, the kidneys become damaged and unable to function properly. As a result, toxins can build up in the body, causing a variety of symptoms. Some of these symptoms may include fatigue, bloating and swelling, nausea, diarrhea or constipation, poor appetite, changes in urination frequency or color, and anemia. Diagnosing CRF involves examining several factors like blood test results and overall medical history. Treatment for the condition typically involves managing any associated symptoms with medication or dietary changes. In some cases, dialysis may also be necessary to support patients with severe CRF. Overall, chronic renal failure is a serious but manageable condition that requires careful monitoring and management by patients and their healthcare providers.

Renal artery stenosis

Renal artery stenosis refers to a condition in which one or more of the arteries that deliver blood to the kidneys becomes narrowed or blocked. This can lead to a number of adverse health effects, including increased blood pressure, chronic kidney failure, and possibly even heart attack or stroke. While there are a number of possible causes for this condition, including genetic factors, certain lifestyle choices such as smoking can also increase the risk of developing renal artery stenosis. Fortunately, treatments are available for this condition, including medications and medical procedures like angioplasty. For those who are diagnosed with renal artery stenosis, early and effective treatment is essential for maintaining overall health and wellbeing.

Renal cancer

Renal cancer begins in the kidneys, which are a pair of bean-shaped organs that filter waste from the blood and produce urine. The most common type of renal cancer is clear cell renal cell carcinoma (RCC), which accounts for about three-quarters of all cases. RCC typically affects middle-aged adults and is more common in men than women. Other types of renal cancer include papillary renal cell carcinoma, chromophobe renal cell carcinoma, and collecting duct carcinoma. Treatment for renal cancer may include surgery, radiation therapy, chemotherapy, targeted therapy, or immunotherapy. The type of treatment will depend on the stage of the cancer and the patient's overall health. Early diagnosis and treatment is essential for the best possible outcome.

Polycystic kidney disease

Polycystic kidney disease, or PKD, is a complex condition that affects the kidneys and other organs in the body. This disorder occurs when small cysts grow in the kidneys, gradually interfering with their ability to filter waste products from the blood. As these cysts start to expand, they can cause a number of severe symptoms such as high blood pressure, chronic pain, nausea and fatigue. In some cases, PKD also results in serious complications such as renal failure or a stroke. However, there are treatments available that can help people manage this disorder and slow its progression over time. By working closely with a medical team and making lifestyle changes to support kidney health, it is possible for people living with PKD to have long and healthy lives.

Urinary tract infection

A urinary tract infection (UTI) is an infection that can occur in any part of the urinary system, including the kidneys, ureters, bladder, or urethra. UTIs are most commonly caused by bacteria, but they can also be caused by fungi or viruses. Symptoms of a UTI may include pain or burning during urination, increased frequency or urgency of urination, cloudy or blood-tinged urine, and pelvic pain. If left untreated, a UTI can lead to serious complications, such as kidney damage or sepsis. Early diagnosis and treatment is essential for preventing serious health problems. UTIs are typically diagnosed through urinalysis, which can detect the presence of bacteria or other organisms in the urine. Treatment usually involves antibiotics to kill the infection-causing bacteria. In some cases, hospitalization may be necessary to treat a severe UTI. Additionally, drinking plenty of fluids and emptying the bladder frequently can help to flush out bacteria and prevent reinfection. Wiping from front to back after using the restroom can also help to reduce the risk of UTI development. Avoiding masturbation devices would good idea if you get frequent urinary tract infections because they can introduce new bacteria into the urethra.

UTI and D-Mannose

A urinary tract infection, or UTI, is a common medical condition that can cause symptoms such as painful urination, abdominal discomfort, and sometimes even fever. While conventional treatments typically involve antibiotics, these medications often come with unwanted side effects like nausea and diarrhea. Fortunately, there is another alternative in the form of D-Mannose, a naturally-occurring sugar that has been shown to help treat UTIs by eliminating bacterial biofilms and relieving symptoms. Unlike antibiotics, which can damage gut health by killing off beneficial bacteria along with the harmful ones, D-Mannose does not disrupt this critical ecosystem. As a result, D-Mannose is becoming an increasingly popular treatment for UTIs, offering an effective and safe alternative to antibiotics.

Kidney stones

Kidney stones are one of the most painful medical conditions to experience. These small, hard deposits form when there is an imbalance in the levels of certain minerals in the body. As they grow larger, kidney stones can cause severe pain as they move through the urinary tract. Treatment typically involves drinking plenty of fluids and taking pain medication. In some cases, surgery may be necessary to remove the kidney stone. Prevention is the best way to avoid kidney stones, and maintaining a healthy diet and lifestyle is the best way to do this. Drinking plenty of fluids, especially water, and eating a diet high in fiber can help to prevent kidney stones from forming.

Glomerulonephritis

Glomerulonephritis is a serious kidney condition that occurs when the tiny filtration units in the kidneys, known as glomeruli, become inflamed and damaged. This can disrupt normal kidney function, causing a buildup of waste products in the bloodstream, resulting in numerous symptoms such as swelling and joint pain. While there is no cure for glomerulonephritis, treatment options can help to reduce inflammation and manage symptoms. These may include medications to control blood pressure or reduce harmful inflammatory chemicals, along with lifestyle changes to support overall kidney health. With proper medical care and close monitoring, many people with glomerulonephritis are able to live healthy lives despite this chronic condition.

Kidney disease is a serious condition that can lead to a variety of health problems. If you have kidney disease, it is important to monitor your symptoms and seek medical treatment as soon as possible. There is no one-size-fits-all approach to managing kidney disease, but by working with your healthcare team and following their recommendations, you can help improve your health and quality of life. Remember, knowledge is power, so be sure to educate yourself about kidney disease and its treatment options. With the right information and support, you can live a full and productive life despite this serious condition.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6399)

Date: April 29, 2022 12:41 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Delta-8 THC Shows Promise in Combating Myocarditis

Heart disease is the leading cause of death in America, and myocarditis is one of the most common causes. Researchers are constantly looking for new ways to combat this deadly disease, and Delta-8 THC may be a promising treatment. A recent study found that Delta-8 was able to slow down heart rate and reduce inflammation in mice with myocarditis. While more research is needed, these findings suggest that Delta-8 could be a valuable tool in the fight against heart disease.

What is myocarditis and what are the symptoms?

Myocarditis is a term used to describe inflammation of the heart muscle. This can occur for a variety of reasons, including infection or injury, and it can cause a wide range of symptoms. Some of the most common signs of myocarditis include shortness of breath, chest pain, and chest tightness. Other possible symptoms include dizziness, lightheadedness, fatigue, nausea, and weakness. If you experience any combination of these symptoms along with changes in your heart rate or blood pressure, it is important to seek immediate medical attention to determine whether you are suffering from myocarditis. Treatment will depend on the specific cause of your condition, but it typically involves anti-inflammatory medications and rest. Early diagnosis and treatment are essential for preventing the progression of the disease and reducing the risk of cardiovascular complications.

What causes myocarditis and how is it diagnosed?

Myocarditis is a condition characterized by inflammation and swelling of the heart muscle. This can lead to a number of symptoms, such as shortness of breath, chest pain, increased heart rate, and cough. There are many possible causes of myocarditis, including infections, autoimmune disorders, metabolic or nutritional disorders, or exposure to toxins or other irritants. In order to diagnose myocarditis properly, doctors will typically perform several different tests. These may include blood tests, scans of the heart using ultrasound or MRI technology, and electrocardiograms to assess heart activity. Ultimately, the treatment for myocarditis will depend on its underlying cause and the severity of symptoms. With proper care, however, most people can recover fully from this condition.

How is myocarditis treated and what are the potential complications?

Myocarditis is a condition that occurs when the heart muscle becomes inflamed. This can be caused by a viral infection, an autoimmune reaction, or other factors. Treatment for myocarditis generally involves addressing the underlying cause, if possible. For example, if the inflammation is due to a viral infection, antiviral medications may be prescribed. Corticosteroids may also be used to reduce inflammation. In some cases, heart surgery may be necessary to repair damage to the heart muscle. Complications of myocarditis can include heart failure and arrhythmias. With prompt and appropriate treatment, however, most people with myocarditis recover fully.

What is Delta-8 THC and how does it work?

Delta-8 THC is a chemical compound that is found in the Hemp plant. Unlike other forms of THC, which produce psychoactive effects by binding to cannabinoid receptors in the brain, Delta-8 simply activates these receptors without producing any noticeable effects on cognition or perception. While the precise mechanism of action for this compound remains somewhat unclear, scientists believe that Delta-8 works by interacting with specific neuroreceptors in the brain and body, thereby triggering a series of responses that ultimately lead to changes in mood or behavior. Furthermore, research suggests thatDelta-8 may also have antioxidant properties and may be effective at reducing inflammation in certain tissues. Overall, while more research is needed to fully understand the pharmacological effects of this compound, it seems clear that Delta-8 has great potential as a therapeutic agent and may hold benefits for patients suffering from certain mood disorders or neurological conditions.

Delta-8, inflammation and relaxation

Delta-8 is a cannabinoid that is found in hemp plants. This compound has a similar structure to Delta-9 THC, the main psychoactive compound in cannabis. However, Delta-8 is much less potent than Delta-9 and does not produce the same psychoactive effects. Instead, Delta-8 provides a more mild physical response that is associated with relaxation and relief from anxiety and pain. Research suggests that Delta-8 may also be effective in reducing inflammation. This anti-inflammatory effect may be due to the ability of Delta-8 to bind to CB2 receptors, which are found in high numbers in the immune system. As a result,Delta-8 may offer a unique combination of anti-inflammatory and relaxant effects.

What are the findings:

The results of recent studies suggest that delta-8, a type of cannabinoid found in cannabis plants, may play a role in reducing the symptoms of myocarditis. Myocarditis is a condition characterized by inflammation and damage to the heart muscle, which can lead to serious complications such as cardiac arrest if left untreated. Early research has shown that delta-8 may be able to help protect against this deterioration, as it was found to reduce levels of oxidative stress and inhibit pro-inflammatory signaling pathways. As more studies continue to explore the mechanisms underlying myocarditis, it is hoped that delta-8 will become an important tool for managing this deadly disease.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6398)

Date: May 08, 2019 03:07 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Oolong tea inhibits the growth and progression of breast cancer cells

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6284)

Date: January 16, 2019 08:50 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Camu camu fruits are rich in an anthocyanin that stops tumors fromgrowing

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5966)

Date: January 04, 2019 08:12 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study: PQQ (pyrroloquinoline quinone) may prevent and even reverseAlzheimer's

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5928)

Date: July 12, 2018 05:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The evidence is clear: Hemp slows the progression of ovarian cancer

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Date: April 24, 2018 09:17 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Smoking marijuana found to have the same weakening effect on the blood vessels as cigarettes

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Date: March 17, 2018 10:15 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Osteoporosis And What You Should Know About Bone Health

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Date: February 19, 2018 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Surprising Anti-Aging Benefits of Fiber

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Date: September 28, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Could CBD oil be used for bone disorders ?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5288)

Date: July 09, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Chaga Mushroom: 5 Health Benefits of This Ancient Medicine

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4945)

Date: May 06, 2017 12:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 4 Ways You're Eating Your Way Toward an Anti-Inflammatory Diet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4547)

Date: April 27, 2017 11:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Omega 3 Fatty Acid Found To Stop Liver Damage From Getting Worse

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4490)

Date: April 21, 2017 06:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How Does Cannabis Affect Your Memory Over Time?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4452)

Date: March 22, 2017 11:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Eating anti-inflammatory foods may reduce symptoms of rheumatoid arthritis

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4260)

Date: March 12, 2017 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamin C effective in targeting cancer stem cells

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4125)

Date: February 21, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Curcumin helps to effectively ease inflammatory bowel disease: China mouse study

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3987)

Date: January 31, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Mushrooms 'can reduce dementia' by boosting nerves in the brain

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3856)

Date: January 23, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 11 best essential oils for arthritis: Control arthritis and inflammation

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3817)

Date: December 25, 2016 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How Oxidative Stress Affects Multiple Sclerosis

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3699)

Date: December 09, 2016 01:35 AM
Author: Darrell Miller
Subject: Boswellia Reduces 5-LOX Activity

Do you tend to suffer from allergic reactions and inflammatory diseases which come as a result of chemicals which are naturally secreted inside the nucleus of the body cells? Well, certain chemicals, such as 5-lipoxygenase is such a reagent inside the blood and it can lead to things such as inflammation in the leukotrienes and other cancer-promoting conditions of the human body. This can even lead to other kinds of discomforts such as joint pains and aches, lung infections and infections of the intestinal tract. As such, it is very important that its activity as well as the impact on the person is reduced. Luckily, there is a solution for that and this comes in the form of Boswellia.

Acting to counteract the effects of 5-LOX, Boswellia otherwise known as Indian frankincense has got a powerful impact on the said chemical which is responsible for the allergic reactions and inflammation of the body cells in the first place. As a result, these reactions are reduced thus promoting a healthy state of being. It is said to be the best natural fighter against the killer cancer and since it comes in an easy to assimilate form, it can get into the body system quickly thus acting to fight reactions just in the nick of time. 

It is truly important to live a healthy life which is free from all kinds of infections and allergies which can develop into further complications for the person. When you have a powerful drug to help with fighting such reactions within your body, you will notice that your body becomes progressively powerful and thus makes you able to withstand certain elements whose imbalances in the body might lead to inflammation. With Boswellia, you are able to become stronger against diseases naturally and you will also observe a gradual progression to a healthier, happier, more wholesome individual.

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Date: December 07, 2016 04:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: High-dose vitamin C reduces inflammation in cancer patients, study shows

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Date: November 29, 2016 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Microbes in your gut influence age-related macular degeneration

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Date: October 30, 2016 04:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Low vitamin D levels linked to Parkinson's and Alzheimer's disease

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Date: July 21, 2015 08:53 PM
Author: Darrell Miller
Subject: What Are Glycosaminoglycans (GAGs) And What Herbs Contain Them?

Glycosaminoglycans refers to a linear unbranched polysacharide chain molecule composed of disaccharides repeats with a high negative charge due to the presence of Uronic acid components and sulfate esters with some hydoxyl (OH) groups as part of its structural components. They have varying molecular size and sulfation depending on the tissue they are located on and their state. They function to attract cations and maintain the hydration of the extracellular membrane (E.C.M).

Glycoaminoglycans are classified into different groups based on different categories which include; glycosidic linkages in their structure, type of the sugar moiety, sulphate groups numbers and the location of the sulfate groups. Based on this various classification categories six major groups of GAGs exists, namely; heparin, hyaluronan, dermatan sulfate, heparin sulfate, chondroitin sulfate, and keratan sulfate.

GAGs have a high solvation degree and and are as well highly viscous. This is beneficial to the body in that it helps to cushion and lubricate various connective tissues and body joints respectively. It therefore protects an individual from joint pains due to poor lubrication of the joints causing the bone to slide over each other. They also form the building blocks of proteoglycans which are the major building blocks of the extracellular matrix. Due to this property they are vital in determining the cellular activities such as cell division because the cell division machinery has to attach itself to the extracellular matrix before the division process is initiated. Some body tissues such as the nerve cells and the muscle cells require continuous cell division to replace worn out cells for the normal functioning. This means that structural deformities in the extracellular matrix will hinder the division process to occur and is most likely to lead to some neurodegenerative complexions.

Recent studies have linked GAGs to play a role in the cell biology of cancer.They have been established as the key macromolecules affecting cell properties and functions through interaction with key growth factors or by acting directly as receptor molecules. Through this it has been findings they play a vital role in the cell signaling process thus playing a role in the cancer disease progression.Heparin and heparin sulfate have been indicated through studies to have anti-tumor effects by preventing the process of angiogenesis which is the first step in cancer metastasis.Some have been associated with anti-coagulant properties.

Therefore GAGs are important molecules which play a vital role in protection against various forms of cancers. GAGs aremostly obtained from animal sources. The animal sources include shark fish and ray skeletons. Plants are also sources of GAGs, however their digestion by the human system is not possible. Seaweed is one herb that is rich in GAGs. However as earlier explain the digestion of the sea weed by the animal digestive system is quite a challenge. It is therefore recommended that we eat foods rich in proteins, and carbohydrates which can be used to synthesize GAGs in the body.

In summary, GAGs are heteropolymers which acts as the building blocks of the extracellular matrix in animals. The body has the ability to synthesize GAGs naturally hence nutritional supplement is required for the body to obtain key components necessary for the synthesis.
links

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Date: August 04, 2014 08:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ginkgo Biloba A Modular Solution To Boosting Memory.

Memory Loss

Memory loss occurs when one loses the ability to remember information and events that you would normally be able to recall. It is usually distressing for the person affected and the family members.

Gingko Biloba Benefits

Ginkgo biloba is effective for memory aid as it improves blood flow to the brain. It can help with memory problems caused by dementia or Alzheimer's disease. It helps to prevent the progression of dementia symptoms. It also helps in the improvement in cognitive function. Taking ginkgo biloba leaf extract by mouth seems to improve thinking skills in elderly people with mild moderate age related memory loss or thinking problems. It improves short-term visual memory and speed of mental processing in non-demented people with age related memory loss and it can improve memory and speed of mental processing in people without memory loss.

Ingredients of Gingko Biloba

The active ingredients in ginkgo biloba are ginkgolides, bilobalides and flavonoids. It works by delaying the symptoms of dementia. Adding ginkgo biloba supplements may help battle cognitive impairments and memory loss associated with dementia since it encourages the growth and development of neural stem cells. It protects the neurons from oxidative damage by potentially preventing the progression of tissue generation in patients suffering from dementia. Ginkgo biloba extracts promotes growth in brain regions.

Due to its benefit of boosting memory, most doctors prescribe ginkgo biloba as the treatment choice for dementia and for age related memory dysfunction. It has been approved for symptomatic treatment of deficits in memory impairment, concentration difficulties and depression from organic brain disease. In conclusion, it is evident that ginkgo biloba extracts helps to stabilize and improve memory loss in several measures of social functioning and cognitive functioning in mixed or vascular dementia patients and Alzheimer's Disease. It might also improve memory and speed of mental processing in people without memory loss.

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Date: March 28, 2014 07:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Bilberry Have Healing Properties?

What is a bilberry

The Bilberry fruit grows in Europe and North America. In Europe, it is known for its mending properties for a long time. Furthermore, Vaccinium myrtillus, is the Latin name for bilberry berries.

Benefits of bilberry

Bilberry discovered generally in dull cleaned fruits. It is utilized to treat loose bowels, varicose veins, and mucous film aggravation. The herb is valuable in the medicine of solidifying of the conduits (atherosclerosis) and in eye health.

This herb might additionally help night vision. Throughout World War II, British Pilots consumed bilberry stick before going out on night flights. They asserted it enhanced their vision. It is accepted that the bilberry herb helps the eyes to change in accordance with progressions in light rapidly. This is one of the best benefits of bilberry and could be exceptionally valuable for one’s eyes as stated by numerous studies.

In Europe, it is utilized to treat venous deficiency a condition that causes swelling and varicose veins. It further assuages torment and tingling, and it likewise. Helps battle skin ulcers on the legs. Reynaud's infection may profit from the bilberry. Reynauds reasons torment and deadness in the external limits (fingers, toes and nose) when chilly.

Bilberry enhances dissemination and makes course dividers. The herb may lessen aggravation, simplicity gastro-intestinal issues, and gum issues that have been joined to coronary illness. Loose bowels and mouth injuries can profit from Bilberry too. Bilberry has solid clean properties, alleviates peptic ulcers, diabetes, fibrocystic maladies, and tormenting feminine cycle.

In view of Bilberry's makes a great free radical forager, which helps battle the cell harm that prompts untimely maturing and malady. The most noted profit that we quickly talked about is its capability to treat an extent of issues identifying with one’s eye health. Case in point, the herb ensures collagen structures in the veins of the eyes, in this way, pushing solid vessels that convey numerous crucial supplements, for example, and oxygen-rich blood to your eye muscles.

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Date: January 21, 2014 10:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CLA in Weight Loss

What is CLA

CLA, or conjugated linoleic harsh corrosive, has been the subject of an assortment of exploration in the previous numerous years. Over 200 studies have indicated that it may assume an exceptionally vital part in weight reduction, as well as in serving to battle disease, diabetes, and atherosclerosis (solidifying of the corridors). It is not made in the human figure, and is discovered commonly in meat and dairy fats, or as an over-the-counter supplement. Artificially, it is a marginally changed type of the fundamental greasy harsh corrosive, linoleic harsh corrosive, and an omega-6 fattening harsh corrosive. The CLA discovered regularly in the sustenance sources is most astounding in dairy cattle and bovines that expend an eating methodology rich in grasses, and the individuals who are nibbling in pastures; instead of the aforementioned bolstered monitored food, for example, grain, feed or silage. To quote Larry Satter, an Agricultural Research Dairy Scientist, "Pasture-nibbled cows had 500% more CLA in their milk than those nourished silage." Since the fat is the particular bearer of the CLA, the substance of the fat in the milk is extremely paramount. The higher the fat substance, the more stupendous the CLA sum is in the milk. This is as opposed to what is proposed when drinking milk. Skim or 1% is constantly proposed over the entire or 2%, to maintain a strategic distance from the overabundance calories and fat, since normally drain was tanked for the calcium content (or the protein). This adds an entire new profit to drain and dairy items, clearing a path for science to control the CLA substance of milkfat, and may open the entryway the CLA-improved sustenances.

Study on CLA

Scientists accept CLA helps square fat cells that are in the figure from topping off with fat by meddling with a fat-archiving compound regarded as lipoprotein lipase, and additionally, by expanding the affectability of units to the hormone insulin. Creature studies have likewise demonstrated an expansion in lean bulk and fat lessening, or fat blazing; furnishing positive progressions to form sythesis, a decline in general muscle to fat ratio ratios. It is known as a "fat eliminator" on the grounds that it revs up muscle metabolism, in this way, helping increment lean tissue, bringing about the figure to need more calories to capacity (since fat units smolder next to zero calories), accordingly accelerating the fat smoldering procedure to make vigor.

Much stays to be looked into the underlying instruments by which CLA pushes its assorted physiological impacts. The profits are genuine, in spite of the fact that more research with people requirements to be carried out. You ought not feel that taking CLA alone would phenomenally make you shed pounds, in the event that you are not joining a brilliant, solid, overall adjusted eating methodology and activity program on top of it.

Reference:

1. //en.wikipedia.org/wiki/Conjugated_linoleic_acid

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Date: November 05, 2013 10:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Bilberry Extract Improve Eye Site?

 Can Bilberry Extract Improve Eye Site?

Do you problems with your eyes? Maybe your night vision is poor and you have been wondering where you can get natural drugs to improve or rectify this condition. Worry no more as this article presents you with the ultimate solution. Research has shown that Bilberry extract works well to improve eye site.

What is Bilberry

Bilberry, an herbal supplement, also known as Vaccinium myrtillus or myrtille, is a shrub found in European countries similar to the huckleberry or the blueberry. This extract has a long history since it was used as early as 16 century. However, it was not until Second World War II when its use was modernized. The first people to use it were the US and British pilots who ate it as part of their diet. Surprisingly, they realized a tremendous improvement in their night vision when they were at work during the night.

This extract is known to be rich in flavorings, also known as polyphenols, a substance that improves eye’s circulatory system and improves the overall eye health. Thus, when supplemented with diet, night vision will be improved.

Uses of Bilberry

In addition, this extract has been known to treat a variety of retinopathy conditions. A condition that damages nerves and blood vessels of the retina. In some countries like France, this extract has been used since 1945 to treat diabetic retinopathy, a condition that causes blindness in diabetics.

Various studies have shown that this extract is a useful medical herb. One of them stated that Bilberry extract could be used with vitamin E to prevent the progression of cataracts. This studies was conducted among 50 patients suffering from cataracts, and only of them did not recover.

Benefits of Bilberry

In conclusion, this extract has many benefits; support for glaucoma, reduce eye fatigue, and improve poor night vision. Therefore, wait no more, get yourself this extract and your eye problems will be something of the past.

References:

1. www.webmd.com/eye-health/features/bilberry-extract-and-vision?
2. hakimclinic.com/blog/2013/08/.../improve-eyesigh-with-bilberry-extract.
3. www.raysahelian.com/bilberrt.html?
4. www.healthy.net/prgm/HealthyAd.aspx?Ad=1383

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Date: January 26, 2013 11:28 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Grapefruit Pectin And Soluble Fiber Health Benefits?

Do you want to know, what are the benefits you're likely to reap from consuming grapefruit pectin?

If yes, then this write up is for you. Scroll down to know more on this.

Typically consumed as for break-fast, grapefruits usually are a favorite for the dieters who are tirelessly working on the various tactics that can assist them in the fat burning process. Grapefruits are well known for their minerals and vitamins, but they are also very great sources of fiber. Grapefruit pectin which is unique form of the soluble fiber has got a number of the health benefits that it carries along. Let us now have a look at some of these benefits that it carries.

Benefits of Grapefruit Pectin

The following are some of the benefits of grapefruit pectin. They include;

• *Preventing Formation of Cholesterol Grapefruit pectin fiber normally binds to the cholesterol and thus prevents it from forming the deposits along the walls of the artery.
  
• *Maintaining the Blood Sugar Levels Grapefruit pectin fiber also slows the carbohydrates from making their way to the blood stream. This thus reduces rate at which the sugars are absorbed. In the long run this assists in maintaining the levels of blood sugar.
  
• *Antibacterial A very powerful antibacterial, the grapefruit pectin fiber normally fights the internal fungi, bacterial infections, and the other harmful parasites.
  
• *Promoting the Health of the Colon Just the same as the other fibers, grapefruit pectin fiber also is as well beneficial when it comes to promoting the health of the colon. This fiber adds bulk to the individuals' stool and hence assists him or her to be able to pass the stool more easily via the intestinal tract. Grapefruit pectin fiber also can prevent hemorrhoids and diverticulitis, while easing symptoms of the irritable bowel syndrome as well as the other bowel complaints.
  
• *Cancer Protection Grapefruit pectin also is believed to have the capability to inhibit growth and metastasis of some certain types of cancers, most particularly those of gastrointestinal tract. According to some researches which were conducted recently, a fragment that was released from pectin was believed to inhibit the galectin 3, a protein which plays a role in all the stages associated with cancer progression.
  
• *Enhancing a Better Immunity: Enhancing better immunity is also another benefit which has been reportedly to come from the grapefruit pectin fiber. This fiber when imputed in any diet will prevent the infections that are normally caused by the microbes such as bacteria, parasites and fungi.
  
• *Healthy Weight Management In addition to the fact that this fiber can easily clear your digestive tract, it can as well assist you in maintaining your weight. This fiber normally gives dieters the feeling that can lead to less consumption of calories. Grapefruit pectin fiber also can inhibit the absorption of some calories from the foods eaten, thus resulting to less weight gain.
  

Last but not the least; as you have seen, grapefruit pectin fiber has got very many benefits. However, before you include grapefruit to your diet, ensure that you consult an experienced dietitian or doctor to know whether it is ideal for your diet or not.

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Date: May 24, 2012 07:43 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are the Benefits of Cat's Claw?

Cat's Claw

Cat's Claw is a supplement that helps people suffering from certain diseases and/or other physical conditions. It is found in the Amazon and is named for the thorny portions of the leaves on the plant. The medication is extracted from the root bark to help achieve healing of an ailing body.

Benefits of taking Cat's Claw Supplements

Digestion- Cat's Claw helps keep the digestive tract on course, easing the pain involved with constipation. It will help assure that a bowel movement occurs on a regular basis. Doctors suggest that a person should have at least one bowel movement per day. If that is not the case, Cat's Claw can help solve the problem.

Arthritis- Arthritic patients often find relief in Cat's Claw supplements. It helps reduce the swelling involved with the disease, making day to day life easier for the patient. Arthritis is one of the most painful medical conditions that a person can contract. There is no cure for it, but Cat's Claw can help patients maintain a more normal lifestyle.

Cancer- Cancer is a deadly disease that can put fear into the bravest of people. Cat's Claw may be able to help in slowing the progression of the disease though. Studies have shown that the ingredients in Cat's Claw deter further cancer cell growth. Studies are still being conducted on this root medicine to determine if it has other effects on cancer as well.

Healing- Cat's claw helps in the process of healing wounds. There are several forms of the drug, including tincture (liquid) form. It can be used much like alcohol is used for wounds to keep it from becoming infected. Cat's Claw speeds up the healing process to avoid a more lengthy recovery.

Ulcers- Cat's Claw helps heal ulcers, a very painful medical condition that attacks the lining of the stomach. Ulcers are a chronic condition that cannot be reversed. The symptoms can be reduced using Cat's Claw in the proper manner.

High Blood Pressure- High blood pressure can lead to heart attacks and/or strokes. Keeping the blood pressure at a normal level is essential to prevent these deadly medical conditions from occurring. Cat's Claw helps reduce high blood pressure so that it heart attacks and strokes do not continue to threaten patients.

HIV­- HIV is the onset of another deadly disease; AIDS. It has led to the death of thousands of people who have contracted it. Researchers are still looking for the cure for the disease. Until they find it, Cat's Claw can help reduce the risk of contracting full-blown AIDS. Cat's claw will not reverse HIV, but it will help those suffering from it have a greater chance of survival. Essentially, Cat's Claw helps slow down the progression of HIV.

Cat's Claw has far too many benefits to overlook. It comes in several forms including tincture, capsule, tablet or herb form. The form taken should be in conjunction with the health issue the patient would like to address. The healing elements of the natural medicine mimic those of the aloe plant, but with many more benefits to help boost greater health.

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Date: March 22, 2012 07:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How DoesTurmeric Help Improve Your Health?

Turmeric - Curcumin

This is a perennial herbaceous plant which belongs to the ginger family making it an important plant because of its active ingredient, curcumin and other properties which makes it avery useful plant in terms of health when used. The rhizomes of turmericare gathered annually for preparation of various health products or foods or taken on its own as they are known to have greater concentrations of curcumin and other substances which are essential for good health. When turmeric is taken, it improves one's health in the following ways:

Weight loss; for those people who are overweight and obese, they always face a challenge on how they can get rid of some extra weight as it is associated with negative health implications and on the other hand fats such as belly fat decrease one's self esteem. Turmeric is one of the herbs that if mixed with food will increase the rate of metabolism which will consequently help in fat loss which will ultimately have an effect on the weight. Thereforemanageable weight will always ensure that one is not at risk of developing cardiovascular heart diseases and other lifestyle diseases which will ultimately promote good health.

Cancer and turmeric; cancer is one of the killer diseases which was very common in developed countries but nowadays it is very rampant even in developing countries. By taking turmeric, the active ingredients in it will help in stopping and preventing the development of cancer more especially prostate cancer which affects men. This herb interferes with the abnormal cell division of the cells hence leading to a stop or prevention of cancer progression thus health improvement. It is important to note that turmeric is also very effective in preventing other types of cancers for example breast cancer from spreading to other parts of the body such as the lungs. The effectiveness of turmeric in fighting cancer can be increased by mixing it with cauliflower flower.

Detoxification; turmeric is rich antimicrobial properties, antiseptic properties which make it a very useful plant when it comes to cleansing of the body. The body is usually bombarded with a lot of chemicals and toxins from the environment and what is eaten hence need to cleanse it. This can be achieved by taking turmeric on its own or mixing it with other foods and taking it two to three times a day for a period of about one month. This will go along way in detoxifying the body more especially the liver which will make it more healthy hence work better as it is one of the largest organ in the body.

Fighting inflammation; this is one of the common symptom of very many ailments and by taking turmeric, it will be able to fight inflammation resulting in improved and good health. It has also been associated with the reduction or clearing of symptoms of arthritis (rheumatoid arthritis and osteoarthritis). This will improvemotion of the patient which willfinally have an impact on performance of the patient thus have a positive impact on the health of those with these conditions.

Turmeric can also be used as a natural disinfectant for example when burns and cuts occur at home, it can be applied thus hastening the healing process.

As you can see, turmeric with curcumin has a wide range of uses, you too should have this wonderful herb on hand in case of emergencies.

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Date: September 19, 2011 06:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Your Diet May Be What's Causing Your Acne

Although dieticians and physicians maintain that diet does not cause acne, this is not strictly true. Even dermatologists argue the point, but while it is generally agreed that eating fatty foods or excessive quantities of chocolate will not in itself lead to acne, there are certain valid arguments that diet has a role to play. Recent research has shed new light on dietary factors that can help to promote acne symptoms, if not being the sole cause of them.

Before discussing that, it is important to understand why acne gives rise to the symptoms that it does: lesions in the form of whiteheads and blackheads, pustules and cysts. While not necessary to discuss the biochemical details, the part that your diet has to play will not be understood without considering the effect of hormones on acne.

The reason that teenagers in particular appear to be more prone to acne is that an increased production of hormones has an effect on the condition that causes the symptoms of acne. Fundamentally, acne is characterized by the infection and inflammation of a mass of oil and dead skin cells within the pores of the skin, particularly on the face, neck, chest buttocks and back. If we discuss each of these elements first, and how they are created, then the relationship between diet and acne will become clear.

At a certain time in their lives, people experience a spurt of growth and develop sexually. This is initiated by the secretion of hormones, particularly of male sex hormones collectively known as androgens, and by various hormonal 'Growth Factors'. This stage of human development is known as puberty, although there is also an increase in androgen secretion by the adrenal glands just before menstruation and during pregnancy and menopause. Androgens such as testosterone are reserved not only for the male of the species!

An effect of androgens is to increase the rate of secretion of sebum from the sebaceous glands in the skin. The reason for this is unknown, though it has been hypothesized that its purpose is to waterproof the additional hair that is grown on the body at this time. Another suggested reason is as an olfactory warning to others to deter from sexual activity, in teenagers until their sexual development is complete, and in pre-menstrual, pregnant and menopausal women for obvious reasons. There is no substantial proof for any of these hypotheses, though the latter appears to make more sense than the former.

Irrespective of this, androgens also interfere with desquamation, and the dead skin cells within the pores tend to fall off irregularly and in clumps. This mix of dead skin cells and excess sebum clogs up the pores of the sebaceous follicles. Once this plug becomes infected with bacteria, the immune system is activated, inflammation occurs, and leukocyte action leads to pus formation. That is what is known as acne.

In order to determine how diet and acne are connected, it would be necessary to determine what components of our diet can either stimulate sebum production, or stimulate androgen secretion. If no such link could be found, then it would be fair to descry any connection between acne and the food you eat. However, there is a connection, and it is a positive one.

In addition to their main function, insulin and a hormone known as IGF-1 (Insulin-like Growth Factor 1 that helps promote growth in children) promote the secretion of testosterone, a male hormone or androgen. Knowing, as we now do, that androgens promote the secretion of sebum, then anything that increases the levels of insulin or IGF-1 within the body will also lead to sebum production and hence to acne. What that infers is that any foodstuffs that increase the insulin levels in the blood can also lead to acne.

This inference is supported in many ways. For example, it has been found that while drinking milk promotes a greater risk of acne, eating yoghurt does not. Why is this? It is known that milk can increase insulin levels because of its high sugar content. The effect of bacterial activity to produce yoghurt reduces the amount of sugars in the milk it is made from because the bacteria live on the lactose. The same argument applies to cheese, which promotes lower insulin levels than milk, if not as low as yoghurt.

This being the case, then a diet low in sugars and carbohydrates should reduce the incidence of acne generally. Recent research has indicated that a diet high in refined carbohydrates and sugar increases both IGF-1 and insulin levels in the blood. This then creates a surge in male hormones which in turn leads to excessive sebum secretion and intermittent shedding of skin cells and so on to the growth of bacteria and acne. It is a logical progression, supported both by theory and by observation.

So how should a person with a propensity for acne change their diet? Switch to fruits, vegetables and grains. Non-fatty meats are also acceptable, and .lots of fish and other seafood. Studies have concluded that diets rich in seafood lead to very low acne rates. The Japanese and coastal Chinese suffer very little acne in comparison with those taking a Western diet, particularly an American diet.

One of the reasons for this is that omega-3 fatty acids help to reduce both inflammation and sebum production. The same is true of green tea that contains antioxidants that reduce the blood levels of dihydotetosterone and hence of sebum secretion by the sebaceous glands. We could go on, and list supplement after supplement that contain antioxidants and other substances that can reduce the production of sebum and hence of the symptoms of acne.

Vegetable oils, on the other hand, with their high omega-6 fatty acid content, can drive up sebum production and the activity of the immune system and the inflammatory response. There are few doubts left that, while acne is not specifically caused by what you eat, diet can contribute to it and that acne and its severity can be eased by eating a diet low in carbohydrates and other sugar-promoting foods.

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Date: August 19, 2011 01:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Lutein Help Fight Against Macular Degeneration?

Macular degeneration is a medical condition that affects older adults in most cases which results in a loss of sight or vision just in the center of the visual field due to damage of the retina. This is a very serious condition of the eye and it progresses over the years and in case left untreated may lead to further loss of sight. It has been found to be a major cause of older adults being visually impaired and usually age range is 50 years or older. Macular degeneration makes it hard or impossible to read or recognize faces, even though enough peripheral vision remains to make daily life activities remain doable.

Lutein from the Latin meaning of yellow, luteus, is a xanthophyll and is a naturally-occurring carotenoid. It is abundant in leafy vegetables which are green in color like spinach and kale. Lutein can also be found in egg yolks and is also present in plants as a fatty-acid tester and most of all, it can be found in the retina and concentrated in the macula, which is a small area of the retina mainly responsible for central vision. This helps the eyes to be protected from oxidative stress and blue light photons with high energy.

Eye Health

Several studies have found that an increase in macula pigmentation helps decreases the risk for eye diseases and one of them is Age-related Macular Degeneration(AMD). Some concluded that visual activity is improved with lutein supplementation alone or lutein together with other nutrients. Other studies also show that AMD seemed to be directly related to having low carotenoids in the body. It does follow in this case that increased green leafy vegetable consumption does help prevent the risk of AMD. Sufficient lutein intake indicates risk reduction for macular degeneration and this can be obtained from a proper diet, but considering that the daily focus of attention is for the lutein.

It commonly follows that this daily attention to the diet to get all the required lutein for our body is where supplementation suggestion comes in since many are not able to do so especially for people around the age group of 70 and up where the attention needed is just too taxing. And since failure to have sufficient lutein is not acceptable for these people with a high risk of AMD or those already with AMD but hopes to slow it down or even stop the progression of the decease, supplementation is a viable and reliable way to assure sufficient lutein intake. This would eventually lead to increases in blood serum levels that would be equal to a diet sufficient of high lutein foods.

However it’s worthy to note that risk reduction does not equate to a cure because once macular degeneration has started there is no way to reverse it. But reduction of risk may be an implication of prevention for some people. Further research needs to be done. However in terms of prevention before the decease starts, results have been promising.

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Date: May 17, 2011 02:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Schizandra Fruit Good for?

Schizandra and your Health.

Schizandra fruit refers to the berries of schizandra. It is widely used in China and the plant is considered one of the 50 fundamental herbs in Traditional Chinese Medicine. It is a highly prized ingredient to a health tonic historically prepared for Chinese royalty and nobility. In recent years it has become available to more people across the globe as cultivation increases to meet large-scale productions. Also, herbal supplements that contain extracts of schizandra fruit are becoming popular.

Schisandra chinensis is an indigenous plant species of, as the name suggests, China. However, its native range goes as far north as Asiatic Russia. It is cultivated for its leaves, bark, and berries. The name of the fruit in Chinese translates as “the berry that possesses all five basic flavors,” inasmuch as the Chinese believe it contains organic compounds responsible for its unique taste: salty, sweet, sour, bitter, and spicy. The berries are often dried and made into tea that can be served hot or cold.

Scavenges Reactive Oxygen Species

Reactive oxygen species, or ROS, are natural by-products of cellular respiration, the process of energy metabolism that takes place within each individual cell. These include peroxides, singlet oxygen, and free radicals. ROS can interrupt cellular activities and even damage DNA synthesis, the reason why each cell has its own antioxidant defense. That being said, cells are overwhelmed by ROS as we age.

The process of aging has been tied to the weakening antioxidant defense of cells. Free radicals are also believed to be responsible for the fast progression of many life-threatening diseases, such as cancer. Schizandra fruit is a natural remedy for oxidative stress, the cellular damage brought on by ROS. The berries are rich in antioxidants that help replenish the antioxidant stores of the body.

Displays Hepatoprotective Properties

Schizandra fruit is particularly good for the liver. Practitioners of Chinese herbal medicine believe that its berries rejuvenate the liver, the kidneys, and the circulatory system by washing away the toxins these tissues have amassed over the years. The cleansing properties of juices and tinctures that contain schizandra have been ascribed to the organic compounds naturally occurring in the fruit.

Lignans are a class of polyphenolic substances that occur naturally in nature. Schizandrin, deoxyschizandrin, gomisin, and pregomisin are lignans unique to the schizandra fruit. The antioxidant properties of lignans are well established, but those found in the berries of this plant species have an affinity toward hepatocytes, or liver cells. It protects liver cells from oxidative damage and raises the capacity of liver to deal with drugs and their harmful metabolites during first pass metabolism.

Increases Physical Working Capacity

Schizandra fruit is a symbol for youth in the East, and for good reason. For one, it is an adaptogen that increases tolerance to stress and raises the physical capacity of the human body. It is also an aphrodisiac believed to enhance libido and improve sexual performance. Modern herbalists believe its aphrodisiac effects are attributable to its stress-relieving properties.

You too can experience the health benefits of schizandra by picking up a bottle at your health food store.

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Date: May 09, 2011 11:14 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Lycopene Help with Prostate Problems

Lycopene and The Prostate.

Lycopene is an organic compound often associated with tomatoes. It is almost always touted to prevent prostate cancer, though the scientific community has not come to a conclusion yet. Scientists are nevertheless positive that it is good for the prostate, for it displays antiproliferative effects on prostate cells. Laboratory studies are very promising as it appears to inhibitory effect on tumor growth.

Prostate health has long been tied to consumptions of foods rich in lycopene. It is a carotenoid that is bright red in color, and as such can easily be obtained from brightly colored plant products, such as watermelon, papaya, pink guava, and apricots in addition to tomatoes. Like other carotenoids, it displays antioxidant properties. In fact, it is the most efficient scavenger of singlet oxygen of all antioxidants that are classified as carotenoids.

Reverses Oxidative Damage

There have been numerous studies on lycopene in the past few decades, and many of them have noted its antioxidant potential. It has become common knowledge that lycopene is good for the prostate, but not all people know that the prostate gland is its primary storage in the human body. Indeed lycopene interferes with the health of cells and tissues that make up the prostate gland.

One study that tracked down malignant prostate tissues prior to scheduled surgical removal studied the effects of regular intake of lycopene. It was documented and published that lycopene concentrations in the prostate doubled and the oxidative damage to DNA in prostate tissues decreased, suggesting a dose-related efficiency in the prevention of cellular damage brought on by free radicals and other reactive oxygen species.

Induces Apoptotic Death

High consumptions of lycopene appear to directly counteract with cancer cells and tumor growth, not only in the prostate gland, but also in the lungs, breasts, ovaries, stomach, and cervix. It has also been tied to other disorders of the prostate, such as prostatitis and benign prostatic hyperplasia, or BPH. It has been noted to slow down cell proliferation that leads to the enlargement of the prostate.

More imporatantly, lycopene seems capable of inducing the cellular process called apoptosis, or programmed cell death, in prostate tissues, most notably in carcinoma regions. This is also evidenced by a significant decrease in prostate-specific antigen in the blood, the reason why lycopene has gained the attention of researchers for prostate health, spurring a number of studies in recent years.

Maintains Prostate Health

Lycopene levels in the human body are largely dependent on dietary intake. As a general rule, the higher the intake of lycopene is, the healthier the prostate becomes. First, it neutralizes reactive oxygen species such as singlet oxygen and free radicals. It also inhibits the multiplication of prostate cells, effectively preventing benign prostatic hyperplasia, which is believed to afflict up to 80 percent of the male population. For those suffering from prostate enlargement, it slows the progression of the disease.

If you are, 40 years old or more you should consider taking lycopene as a preventative daily!

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Date: May 07, 2011 11:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Important are Minerals in the Body

Minerals And Your Health.

Minerals are nutrients necessary for human life. They are often found in the foods we eat at dietary quantities. Living a healthy lifestyle always means having the right amounts of minerals in our diet. Each mineral has a daily value, which necessitates its consumption on a regular basis. Not meeting the requirement for a single mineral for extended periods of time will lead to deficiency.

Deficiency in any nutrient will always impact our health. Minerals are especially important because they are very pervasive throughout the human body. They even affect the digestion and absorption of other nutrients. It is common knowledge that long-term deficiency in any mineral will have deleterious effects on human health that may even result in malnutrition and faster progression of diseases.

Quantity Minerals

Dietary minerals are actually chemical elements that are involved in countless chemical reactions in the human body. It is very probable that various tissues and organs will collapse when these elements progressively decrease. Some elements are necessitated in relatively large amounts, and this group of minerals is called quantity elements, which include potassium, chlorine, sodium, calcium, phosphorus, sulfur, and magnesium. Human health is quite sensitive to low levels of these minerals.

Potassium is an electrolyte present in systemic circulation to regulate blood pH. Chlorine is generally obtained from table salt, which is indispensable in the synthesis of gastric acid. Sodium, like potassium, is a systemic electrolyte that also participates in many cellular functions. Calcium is required by almost all tissues, and absolutely necessary for bone health. Phosphorus is involved in the upkeep of several tissues, including bones. Magnesium plays a pivotal role in the metabolism of energy.

Trace Minerals

Trace minerals refer to dietary elements that are needed in, as the name suggests, minute quantities. A significant fraction of the global population has been reported to be deficient in most of these elements in that their intake has been associated with foods that are not consumed on a daily basis. In the past few decades supplementation seems to be the only certain way to obtain healthy levels of trace elements, which include zinc, iron, manganese, copper, iodine, selenium, and molybdenum.

Zinc is necessitated by over a hundred proteins that belong to all classes of enzymes. Iron prevents iron deficiency anemia since it is central to the production of hemoglobin. Manganese binds to proteins and activates their biological roles in enzymatic reactions. Copper and molybdenum participate in the metabolism of oxygen, which occurs in every cell of the body. Iodine is pivotal to the biosynthesis of thyroid hormones, influencing physical growth, mental development, and metabolic rate. Selenium boosts the immune system and improves the antioxidant defense of cells.

The scientific community has estimated the recommended daily allowance for each dietary mineral for good reason. Regular intake of minerals helps ward off diseases and keeps our body in prime condition.

Minerals are essential for life, are you getting enough of them daily?

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Date: March 11, 2011 11:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why is It so Important to Give Your Child a Multiple Vitamin Mineral Supplement

Giving a multiple vitamin and mineral supplement to your child is tantamount to protecting him or her from the unknown dangers of malnutrition. It is a fact that children are picky eaters. Besides, not all food that you put on the table provides all the nutrients that they need. Experts remain divided over the need to give children daily multivitamins, but it is a common belief that doing so is just the prudent choice to make as parents. Does it make any difference? Yes, it does. Research has pointed to the positive effects of vitamin supplementation, and it has been cited a lot of times that the bioavailability of these supplements is not bad at all. This means supplementation does contribute to the well-being of your child.

Ensures to Meet Nutrient Needs

It is not a myth that our diet does not contain all the nutrients that we need. More often than not we are not getting the daily value for all vitamins and minerals as most of us are not able to monitor our eating habits. Also, we don’t have control over how sources of these nutrients change as they undergo the process of heating foods and other cooking preparations. With children being so picky, it is not surprising that they are susceptible to malnutrition. On the other hand, supplementation has been supported by decades-old research to meet the nutrient needs of individuals, including children. If you decide on giving your child multiple vitamin and mineral supplement, do check the label to make sure it says it contains 100 per cent of the recommended dietary intake of all nutrients.

Affects Growth and Development

A number of nutritional supplements available today have been proven to be of utmost help to the reversal of many medical signs and alleviation of diseases. Some of them have been associated with having a positive effect on the chemical reactions within the human body, and multiple vitamins and mineral supplements belong to this category. There is an ever-growing body of literature devoted to the interactions of exogenous compounds within the human body. Research on multivitamins in particular is among the most advanced in pharmacology, with emphasis on how the body effectively digests and absorbs them. Since the availability of vitamins and minerals is important to the physical and mental development of children, modern-day technology focuses on their absorption.

Strengthens Immune Defenses

There is scientific consensus that micronutrients, even trace minerals, boost our immune system. In fact, in individuals who have compromised immune responses, high quantities of vitamins and minerals slow down the progression of opportunistic diseases, as is the case with children with HIV. Children who have strong immune system are known to have levels of micronutrients adequate to ward off common illnesses. The opposite is also true. Multiple vitamin and mineral supplements have long been used to combat the dire effects of malnutrition as deficiencies are almost always reversed with supplementation. That being said, prevention is always better than cure.

Ensure you are getting the daily vitamins and minerals you need to maintain good health with a quality multiple vitamin and mineral.

What is stopping you from taking a multiple today?

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Date: March 10, 2011 02:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does the Herb Holy Basil Help with My Health?

Holy Basil And Cholesterol, Inflammation, and more

Ocimum tenuiflorum, known as Holy Basil in the vernacular, is an herbal plant indigenous to South Asia, where it is called Tulsi. It is widely distributed across the subcontinent of India and surrounding countries and is primarily cultivated for its age-old medicinal benefits in addition to its religious significance to Vaishnavite practices of Hinduism. It has earned popularity as a health tonic over the centuries, and recent studies have supported its positive effects on human health. Today it is often associated with lowering cholesterol and glucose, acting as an antioxidant, and regulating inflammatory intermediaries.

Counteracts Stress Factors

The juice of holy basil has long been reputed to display adaptogenic properties. There have been countless accounts of its effectiveness in combating stress. In fact, the most compelling of all anecdotal evidence has something to do with its ability to create a feeling of wellness right after ingestion, the same tonic benefits attributed to ginseng. To date studies point to its homeostatic effects on the stress hormone cortisol, creating homeostatic effects on its metabolites and their interactions with compounds released in response to stress.

Neutralizes Free Radicals

Holy basil has been observed to show antioxidant activities, and this is one of its mechanisms in allaying symptoms brought on by fatigue. Free radicals are released by the body to dispose of pathogens, but are in turn disposed of by endogenous antioxidants. Oxidative stress ensues when there is an imbalance between the production of free radicals and the ability of the body to neutralize them. The polyphenols found in holy basil helps the body quench excesses of free radicals.

Lowers Bad Cholesterol

There has been a growing body of literature devoted to the lipid-lowering properties of holy basil. The phytochemicals found in holy basil have been cited to affect the metabolic pathway that produces very-low-density lipoproteins, which is a precursor to low-density lipoproteins, or bad cholesterol, and bring about an increase in high-density lipoproteins, dubbed good cholesterol. Also, it has been associated to the overall decrease of lipids present in the bloodstream, notably free fatty acids.

Reduces Blood Glucose

One of the earliest observations on the health effects of holy basil is its properties that counter the progression of diabetes. It has been reported many times to have helped patients of type 2 diabetes mellitus, which results from the compromised ability of cells to respond to the hormone insulin. The use of holy basil extracts has yielded promising results on promoting the glucose uptake of cells, and, of course, the consequent decrease in glucose present in the blood.

Influences Inflammation

Holy basil has been extensively studied for its anti-inflammatory benefits. The most recent research has pointed out that organic compounds found in holy basil may inhibit the enzyme called COX-2, which facilitates the synthesis of inflammatory mediators. Eicosanoids are endogenous substances produced by local tissues during inflammation, and a special group called prostanoids is responsible for the pain tied to inflammation. By targeting COX-2, holy basil greatly aids against inflammatory diseases such as arthritis.

What is stopping you from giving holy basil a try today?

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Date: February 08, 2011 04:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lycopene is More than Just a Tomato Extract!

Lycopene is a naturally occurring antioxidant, and a very powerful one at that. Like beta-carotene, it is a carotenoid, a phytochemical that gives certain plants their orange or bright red pigmentation. While lycopene belongs to a group of carotenoids called carotene, known precursors of vitamin A, it does not get converted into vitamin A inside the human body, which is not a bad thing, inasmuch as lycopene in itself exhibits antioxidant properties that surpass the effects of vitamins.

Tomatoes are very rich in lycopene, and indeed consumptions of tomatoes have been reported to show the antioxidant properties of lycopene. Papayas, pink guavas, and watermelons are also good sources of this compound, but the plant source identified to have the highest concentrations of lycopene is Gac, in English also known as Sweet Gourd, a bright red fruit native to Southeast Asia and largely unknown to the rest of the world. With that, a significant fraction of the total lycopene consumption worldwide is derived from tomatoes.

Reactive Oxygen Species (ROS)

Chemical reactions in the human body that respond to the presence of oxygen are part of a process called oxidation, which takes place everywhere else in nature. These reactions entail a change in the oxidation number of atoms or molecules involved in the movement of electrons between molecules inside the body, giving rise to toxic by-products collectively known as reactive oxygen species.

When cells produce the energy that they use to power their physiological functions, they also produce reactive oxygen species, or ROS, which is now believed to be a key factor in the progression of physical infirmities associated with the aging process of human beings and other mammals. That being said, ROS are actually in the employ of the immune system, and particularly effective against pathogens, which may be invasive extracellular matter or harmful microorganisms.

Every single cell make use of enzymes that change the chemical makeup of unnecessary ROS, which must always be kept in check as they damage cells even at low amounts. These enzymes outmaneuver the damaging activities of ROS, thereby protecting the cells. In spite of that, the human body is known to produce more ROS as we age or during long-standing exposure to stress.

Lycopene versus ROS

One type of ROS is singlet oxygen, a form of oxygen that is highly reactive to free radicals. In fact, singlet oxygen is a known catalyst of free radicals especially when it gets excited at the molecular level. Lycopene is the best known carotenoid to counter the damaging effects of singlet oxygen in the human body, and reported to have antioxidant properties far superior to vitamin E and glutathione.

The good thing about lycopene is that its bioavailability compounds when exposed to heat, so cooking tomatoes actually brings out the goodness of this chemical compound. Lycopene acts against the proliferation of cancer cells in a number of mechanisms, and, to date, there have been innumerable reports in support of the role of lycopene against most known types of cancer.

Have you had your Lycopene today?

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Date: May 27, 2010 12:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Take Control Of your Inflammation With Supplements

Chronic inflammation is often induced by uncontrolled oxidative stress (free radical damage). It is the principle mechanism by which degenerative disease takes hold. By reducing oxidative stress and changing the balance within the body to favor the production of anti-inflammatory chemical messengers, one can lower their levels of inflammation. This can be achieved through conscious changes to diet and lifestyle, which includes appropriate supplementation.

By consuming foods that are rich in omega-3 essential fatty acids, EPA, and DHA, derived from fish oil or flax seeds, one can greatly influence and reduce inflammation. When the body has appropriate balances of omega-3 and omega-6 essential fats, the production of anti-inflammatory prostaglandins is favored and inflammation is kept in check. Increasing the consumption of foods that are rich in omega-3s or supplementing with a high quality fish oil suppresses the formation of harmful prostaglandins and also promotes the synthesis of beneficial prostaglandins. Since the average North American diet contains 10 to 20 times the amount of omega-6 oils that we need, the most sensibly dietary approach is to reduce sources of omega-6 oils and supplement with a high dose of omega-3 oils in order to achieve the optimal 4:1 ratio of omega-6 to omega-3.

Supplementing with flaxseed oil is another effective way to optimize your omega-6 to omega-3 ratio. Anti-inflammatory EPA can be manufactured in the body by converting the alpha-linolenic acid that is often found in flaxseed oil. Supplementing with this oil, along with restricting omega-6 fatty acid intake, raises tissue EPA levels to those comparable to fish oil supplementation. It should even be noted that flaxseed oil contains more than twice the omega-3 fats as fish oil. Additionally, alpha-linolenic acid can be found in a variety of other plant source including pumpkin seeds, walnuts, and other nuts. However, flaxseed is by far the richest source of omega-3 oil, carrying 58% by weight.

Another nutrient that plays a crucial role in inflammation is gamma tocopherol. This nutrient acts through a mechanism that is unavailable to alpha tocopherol by reacting with RNO radicals to subdue inflammation. Gamma tocopherol also has the ability to reduce inflammation by inhibiting COX-2 , which is an enzyme that has a central role in the inflammatory process as it controls the synthesis of the inflammatory prostaglandin. The consuption of gamma tocopherol has been found to reduce several other inflammatory protagonists at the site of inflammation. Strong evidence has found that this form of vitamin E exhibits potent anti-inflammatory properties that are extremely important for human disease prevention and therapy.

Similar to essential fatty acids is resveratrol and green tea polyphenols each of which have the ability to inhibit the activation of NFkB and control a wide variety of inflammatory pathways. Green tea polyphenols are also believed to be neuroprotective, as they invoke a spectrum of cellular mechanisms such as the chelation of metals, scavenging of free radicals, and modulation of mitochondrial function in nerve tissues. Green tea polyphenols are now considered to be therapeutic agents that can alter brain processes and serve as neuroprotective agents in the progression of neurodegenerative disorders like Alzheimer’s and Parkinson’s disease.

There are a wide variety of nutrients that are involved in fighting systemic inflammation. These nutrients and nutrient categories include EPA and DHA, linolenic acid, gamma tocopherol, alpha-lipoic acid, vitamin C, flavonoids, procyanidolic oligomers, and the phenolic compounds found in green tea, turmeric, and olive extracts. When changing your diet from saturated fats to unsaturated fats and adds more fruits and vegetables to their diet along with antioxidant vitamin supplements, one can successfully reduce inflammation naturally and live a healthier happier life.

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Date: April 25, 2010 06:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Good and Bad of an iron supplement

Iron holds a crucial role in the physiology of the body. It is a central part of the haemoglobin and myoglobin molecules. Iron is indispensable to the body’s ability to transport gases into and out of the cell. It is necessary in many important enzymes that are involved in energy production, metabolism, and DNA synthesis. Some iron is lost when red blood cells are broken down and excreted in the bile. However, because of iron’s importance, the body is able to conserve iron at all costs, as the kidneys do not eliminate the metal.

The dark side of iron supplementation comes when iron is consumed in amounts that are excessive to the body’s needs. Although unbound iron is more likely to cause oxidative challenges through the generation of free radicals, excessive iron supplementation in any form can cause huge problems for the cell. The overload of iron can cause deterioration of the gut lining, vomiting and diarrhea, abdominal and joint pain, liver damage, loss of weight, and intense fatigue. In children, acute doses as low as 3 grams can cause death.

About one out of every 250 North Americans suffer from haemochromatosis, which is a genetic defect that is common in a lot of those people of northern European descent. This disorder causes the body to accumulate and abnormally store high levels of iron. Those people with haemochromatosis store twice as much iron as others, which places them at increased risk for iron-related diseases. Symptoms of these diseases generally occur after fifty years of age and often include things ranging from fatigue, abdominal pain, achy joints, impotence, and symptoms that mimic diabetes.

Several studies have produced evidence which suggests that high levels of iron contribute to noticeable increases in the risk for cardiovascular disease. This is likely due to non-haeme iron’s aggressive pro-oxidant nature. Iron levels are one of the strongest biochemical markers for the progression of atherosclerosis, which results from increased oxidation of LDL cholesterol. A study in 1995 conducted on Finnish men found that those who had high body stores of iron also had a substantially increased risk of heart attack. Those men who posses the highest levels of stored iron often showed a levels of risk that was up to three times that of men who possessed the lowest levels of stored iron.

Disorders in iron accumulation contribute to a whole host of other disease states, all of which are degenerative in nature. Studies have shown that chronic iron overload contributes to increased infections, cancer, arthritis, osteoporosis, diabetes, and various congenitive dysfunctions. The only way to remove excess iron is through blood letting, unless you are a woman with regular menses. That is why, for men, iron overload can provide quite a problematic issue. Recent research has found that long-term supplementation with iron at doses less than 5 mg/day can lead to iron-overload toxicity. Because of this, it is recommended that the upper limit of iron intake be at 5 mg/day when considering a product’s rating. Any product that contains iron at a daily dose greater than this limit is penalized with this rating criterion.

But for those who need iron, it can easily be obtained through a vitamin supplement at your local or internet health food store. Men should avoid iron supplements and products containing iron, but women on the other hand due to monthly blood loss should supplement with iron regularly.

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Date: March 30, 2010 05:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Germanium and Oxygen absorption

Germanium, like gold and silver, is a naturally occurring trace element. Although it is considered a trace mineral, it is also referred to as a semimetal. There is no simple difference between a metal and a mineral. Many people have become interested in and excited about this product. However, little research was done on germanium until 1950.

This trace mineral is important in the body for many reasons. It helps to improve oxygenation on a cellular level which is essential for keeping the immune system healthy and also for eliminating toxins from the body. Life depends upon an adequate availability of oxygen. Germanium is responsible for enabling better usage of oxygen on a cellular level. Reports have stated that germanium has many beneficial effects. It has been used to reduce pain. Additionally, it has been found to help with respiratory diseases in order to improve oxygen utilization. Evidence has also been found that germanium is able to help improve circulation. In Raynaud’s disease cases, germanium is able to help improve warmth in the fingers and toes within one half hour. For those individuals who are healthy, warm occurred within minutes. Germanium may also benefit those people who are suffering from strokes or an insufficient amount of oxygen. This substance may also help to remove or detoxify the body of metal poisoning through its chelating ability. Germanium is often recommended for those dealing with liver disease and arthritis.

Germanium possesses both antiviral and antitumor properties. This trace mineral was found to slow the progression and speed of tumors, which in turn prolonged life. Research is continuing in Japan which is studying the effects of germanium-132, which is also known as Ge-132, on different forms of cancer and disease. It may help the body by increasing oxygen supply, to which cancer cells are extremely sensitive. With oxygen utilization improved, the cancer cells may not be able to survive. Additionally, American scientists are in the process of researching this product. Germanium was first discovered to be beneficial to one’s health by a Japanese scientist by the name of Dr. Kazuhiko Asai. Dr. Asai, a chemist, became interest in germanium extraction from coal. After hearing reports that Russians used germanium as a rejuvenator, he studied the germanium in plants. From studies he concluded that germanium was able to enhance oxygen utilization in both plants and animals. Additional studies with mice led him to find that less oxygen was required in order to maintain respiration, as long as those tissues were supplemented with germanium.

Research has determined that germanium may be beneficial in helping with conditions including cancer, allergies, arthritis, cholesterol, viral infections, and AIDS. This trace element has proven to be successful in a variety of studies. Additionally, the benefits of this substance are just beginning to be understood. Germanium will, undoubtedly, become an important supplement as more information continues to be made available. It is important that one consults their health care provider before using this, or any other form of vitamin supplements. For more information on the many beneficial effects provided by germanium, please contact a representative from your local health food store.

~video~

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Date: March 27, 2009 01:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Phytoestrogen

Menopause is the time at which a woman stops ovulating and menstruation ceases, which indicates the end of fertility. Menopause is not a disease, but rather a natural progression in life, similar to puberty. Many years before a woman stops ovulating, her ovaries will begin to slow their production of the hormones estrogen, progesterone, and testosterone. Estrogen and progesterone are often thought of as the reproductive hormones.

Although estrogen is essential in reproduction, it is also extremely important in other non-reproductive organs and systems in the body. Cells in the uterus, bladder, breasts, skin, bones, arteries, heart, liver, and brain all contain estrogen receptors. These organs need this hormone in order to stimulate these receptors for normal cell function. Estrogen is needed to keep the skin smooth and moist and the body’s internal thermostat working properly. Estrogen is also essential for proper bone formation. Even though estrogen levels drop sharply after menopause, they do not disappear entirely. Other organs take over for the ovaries, continuing to produce a less potent form of estrogen. These organs, known as endocrine glands, secrete some hormones from fatty tissue in order to maintain bodily functions.

Progesterone works along with estrogen, stimulating changes in the lining of the uterus to complete the preparation for a fertilized egg during the second half of the menstrual cycle. If no egg is fertilized, the uterine lining is broken down and expelled, allowing the cycle to being again. Progesterone also has effects beyond the reproductive system, as it calms the brain and also affects other aspects of nervous system function. Testosterone is most important for both men and women, with women producing about 80 percent less than men do. However, it is the driving force for maintaining a healthy life and proper functioning organs.

The period when a woman’s body is preparing for menopause is known as perimenopause. For the majority of women, hormone production beings to slow down then they reach their thirties, continuing to diminish with age. Many women will experience few if any symptoms at this time, but others may suffer from anxiety, dry skin, fatigue, feelings of bloating, headaches, heart palpitations, hot flashes, insomnia, irritability, decreased interest in their significant other, loss of concentration, mood swings, night sweats, reduced stamina, urinary incontinence, uterine dryness and itching, weight gain, cold hands and feet, joint pain, hair loss, and/or skin changes.

Menopause occurs when a woman stops menstruating altogether. At this point, most of the acute problems a woman may have experienced are actually over and a new balance between all hormones should be established. However, women become increasingly vulnerable to other, potentially serious health problems at this time. Over the long term, the diminished supply of estrogen increased the likelihood of cardiovascular disease, osteoporosis, and uterine atrophy. Osteoporosis especially is a major problem for women after menopause, with an estimated 80 percent of the hip fractures that occur in the United States every year being due to osteoporosis.

A proper diet, nutritional supplements, and exercise can help to minimize or eliminate most of the unpleasant side effects of menopause. The following nutrients are recommended for dealing with this stage of life: beta-1, cerasomal, coenzyme Q10, DHEA, essential fatty acids, lecithin granules, a multi-enzyme complex, soy protein, vitamin B complex, vitamin D3, vitamin E, boron, calcium, magnesium, quercetin, silica, zinc, l-arginine, multiglandular complex, a multivitamin and mineral complex, vitamin C, aloe vera gel, slippery elm, damiana, amaranth, chickweed, dandelion greens, nettle, seaweed, watercress, anise, black cohosh, fennel, licorice, raspberry, sage, unicorn root, wild yam root, hops, valerian root, gotu kola, red clover, dong quai, St. John’s wort, and Siberian ginseng.

All these above listed vitamins and herbs are available in capsule, tablet, or powder forms. When looking for natural alternatives to help replace estrogen naturally, look to your local or internet health food store for name brand products that can help restore an imbalance over time.

--
Vitanet ®, LLC

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Date: February 16, 2009 01:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glaucoma (loose your eye sight)

Glaucoma is a group of diseases that affect the optic nerve and can lead to irreversible vision loss. It is usually associated with elevated fluid pressure within the eye. All forms of glaucoma can cause damage to the optic nerve and lead to vision loss, even blindness, if left untreated. About 2.2 million Americans have been diagnosed with glaucoma and as many as 2 million more could have it and not yet know. It is one of the lading causes of blindness and is expected to become more prevalent in years to come due to the growing population of older adults.

Those people who are at greatest risk for developing glaucoma are people over the age of sixty, people of African ancestry, and people with diabetes, high blood pressure, severe myopia, or a family history of glaucoma. Smokers also have an elevated risk, as do those who have sustained eye injuries or who have used steroids for an extended period of time.

About 3 percent of Americans are believed to have open-angle glaucoma, which is the most common form of this disease. Because this disorder causes no symptoms until it is quite advanced, only about half of those who have it are actually aware of it. In open-angle glaucoma, there is no physical blockage and the structure of the eye appear to be normal. However, the drainage of fluid is inadequate to keep the intraocular pressure at a normal level.

The most pronounced symptoms of open-angle glaucoma are the gradual loss or darkening of peripheral vision and a marked decrease in night vision or the ability of the eye to adjust to darkness. Other possible symptoms include chronic low-grade headaches, the need for frequent changes in eyeglass prescription, and/or seeing halos around electric lights.

A far less common, yet more serious, form of glaucoma is closed-angle glaucoma. Closed-angle glaucoma is much more dangerous than open-angle forms because it almost never manifests any symptoms until very late in the condition. By that time, vision may be irreversibly damaged.

Glaucoma probably has many causes, with many scientists believing it may be closely linked to stress and nutritional problems or disorders like diabetes and high blood pressure. Some think that excessive amounts of glutamic acid, which is a nonessential amino acid, may be involved. Glaucoma has also been linked to deficiency in nitric oxide, which is a molecule that is critical for healthy blood vessels. Problems with collagen, the most abundant protein in the human body, have been linked to glaucoma as well. Collagen increases the strength and elasticity of tissues in the body, especially those of the eye. Collagen and tissue abnormalities at the back of the eye contribute to the clogging of the tissues through which the intraocular fluid normally drains. This results in elevated inner eye pressure, leading to glaucoma and related vision loss.

The following nutrients are considered to be very important when dealing with and preventing glaucoma: choline, essential fatty acids, glutathione, rutin, vitamin A, vitamin B complex, vitamin C with bioflavonoids, vitamin E, alpha-lipoic acid, magnesium, a multivitamin and mineral complex, and zinc. Additionally, the following herbs are helpful: bilberry, chickweed, eyebright, coleus forskohli, fennel tea, chamomile, ginkgo biloba, zinc sulfate, jaborandi, and rose hips.

To resolve issues with the eyes, one must change their diet, exercise, and take supplements and herbs like what are listed above. Medical doctors are at a loss as to how glaucoma happens but they can help stop the progression of this disease if detected early on. Always consult your doctor before adding vitamins and herbs to your diet, vitamins and herbs are available at your local or internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Date: August 05, 2008 01:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Trace Minerals

Unlike macro-minerals such as calcium, which the body needs in gram amounts, trace minerals such as iron, selenium, zinc, silicon, chromium, sulfur, and copper are only needed in milligram or micrograms. However, these small quantities do not reflect the importance of trace minerals, as inadequate intake can have huge effects on the body. Lets discuss a few of these trace minerals.

Iron deficiency is the most common nutritional deficiency worldwide, with 20 to 50 percent of people affected. The average body contains only one teaspoon of iron, but this mineral is crucial in oxygen transportation throughout the bloodstream and into cells. A lack of iron will starve the body of oxygen and energy, which cause the symptoms of iron deficiency to be fatigue, foggy thinking, irritability, headaches, and lethargy.

A lot of athletes have inadequate iron intake, impairing their exercise performance as it decreases hemoglobin levels and the amount of oxygen that is delivered to the muscles while it increases the time that is needed to recover from exercise. Iron is also important in immunity, with optimal iron intake strengthening the immune system and building resistance to colds, infections, and diseases. Even though inadequate intake is a common concern, too much can also cause health problems including stomach and intestinal cramps, nausea, and constipation.

The most important function of selenium is its antioxidant enzyme glutathione peroxidase. This enzyme is invaluable in protecting red blood cells and cell membranes from free radical damage. Selenium works closely with vitamin E, sometimes replacing it in certain situations. Selenium holds an important role in maintaining the immune system and has been shown to reduce the risk of many health problems which include several types of cancer, heart disease, rheumatoid arthritis, and certain birth defects.

Zinc is a valuable antioxidant that supports many aspects of the immune system. Zinc works in the eyes to protect them against sunlight-related free radicals. Zinc supplements have been found to slow the progression of macular degeneration, but high intakes of zinc and other antioxidants have been shown to lower the risk of developing this eye disease in the first place. This mineral can reduce the severity and duration of the common cold when in lozenge form, if started within 24 hours of the first cold symptom and taken every couple of hours. Taking 50mg of zinc daily or higher amounts for short periods of time is a good idea, but amounts over 150mg daily could cause metallic taste, stomach upset, or impair immune function.

Many modern diets contain extremely low amounts of silicon, especially since food processing removes much of the silicon. Silicon improves the elasticity and suppleness to skin that has been damaged by excessive skin exposure. Silicon is also important in natural bone formation, since deficiencies in silicon lead to bone weakness and sluggish wound health. Bone mineral density can be improved in people with osteoporosis by raising the intake of silicon.

Chromium is important in maintaining blood sugar levels, as well as many other roles in the body. Chromium deficiency impairs the blood sugar-insulin relationship, while chromium supplementation improves insulin response. Studies have shown that supplementing with chromium picolinate improves diabetes management by lowering blood sugar, insulin, cholesterol, or triglyceride levels and reducing the reliance on blood sugar medications. This mineral is also important in the metabolism of fat and carbohydrates.

Finally, Sulfur is needed in the joints to keep the connective tissues within them strong and stable. One source of sulfur, MSM, has been shown to significantly relieve pain and improve use of knee joints in studies. Through all of the above, one can see that trace minerals are extremely important contributors to health, even in small amounts.

Trace Minerals

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Dandelion

Date: June 20, 2008 02:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Dandelion

That common yard or roadside plant you see during the growing season can be your ally against sickness and disease. The common dandelion has many essential vitamins and minerals inherent in it that can be part of your health regimen. Dandelions are an all-natural way to promote good health when used wisely.

The dandelion root and leaves contain vitamins A, C and D, as well as the B-complexes. They also contain iron, magnesium, zinc, copper, potassium, manganese, choline, boron, calcium and silicon. Choline has shown to improve memory function. Dandelion has found use as a treatment for breast illnesses, bloating (water retention), aching joints, skin problems and gastrointestinal disorders. It is also as a gentle diuretic and a purifier for the bloodstream and liver.

This plant contains luteolin, which is an antioxidant and beneficial as an immune system enhancer. Luteolin helps inhibit the degradation and wearing down of the body's cells. What's great about dandelion and its antioxidant properties is the fact that there is no toxic effect on cells associated with it.

Dandelions are also a medicinal herb. They increase waste elimination in the body through the urine. Like green tea's effects, this excretion of water and waste can lead to weight-loss. Dandelion is available naturally, as well as in pill, liquid, tablets and tea form. The Puritans used it strictly as a vegetable, although some who eat it as a prepared dish consider it to have a bitter taste.

This plant has ranked high in many categories. It is one of the top six herbs in the Chinese herbal medicine chest. It is one of the top four green vegetables rated for overall nutritional value according to the USDA Bulletin #8, "Composition of Foods" (Haytowitz and Matthews, 1984). It is food rich in fiber. This is important because fiber is an essential component of a complete weight-loss program. Fiber absorbs fat molecules and aids in their elimination from the body. This prevents fats from absorbing into the body.

The dandelion is part of the sunflower family. It is prevalent in temperate regions in Europe, Asia and North America. This plant finds itself a big part of culinary recipes. Taking the dandelion in this form is good for health, as it is in its most natural, unprocessed state. Some use dandelion as a tea to help in the fight against fever, insomnia and jaundice. Dandelion tea can also aid those who have rheumatism, eczema, constipation and even skin diseases.

It aids digestion by stimulating stomach secretions. However, it does increase the flow of bile in one's system, so you should not take dandelion if you have obstruction of the bile ducts. While generally safe, like anything else, you should consult a doctor when trying something new in your diet. This is to make sure it doesn't have harmful side effects or interact negatively with other herbs and medications.

For women, dandelion helps because of its diuretic capabilities. This means it helps eliminate excess water from a woman's system, which causes bloating.

Those who experience premenstrual syndrome may find dandelion helps bring down their bloating and weight gain associated with water retention.

Another promising aspect of dandelion is the fact it contains lecithin. Lecithin is a lipid that contains choline primarily, along with inositol, phosphorous and linoleic acid. Lecithin elevates the brain's acetylcholine, which helps brain function. This, some researchers believe, may help slow down or stop the progression of Alzheimer's disease. Dandelion, again because of lecithin inherent in it, is beneficial for prevention of arteriosclerosis and cardiovascular disease too.

Sometimes we need to look only in our own backyards and surrounding environments to find plentiful foods that are healthy. Dandelions are one of earth's products that have found use for centuries. Whether as a recipe ingredient, a tea or a pill, dandelion is versatile. When used with care, it can help with weight-loss and be a health enhancer at the same time.

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The Prevention and Treatment or Prostate Cancer

Date: April 10, 2008 01:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Prevention and Treatment or Prostate Cancer

Last week I shared with you the controversy surrounding the use of PSA screening to determine the status of the prostate. There are many doctors who do not believe that using PSA is accurate enough to rely on for determining whether or not a high PSA indicates prostate cancer. Many men, who have a high PSA, after more detailed examination, did not have cancer and men with a low PSA did have cancer. Some physicians do not believe that the current methods of diagnosing prostate disorders are saving lives. Also, there is a group of physicians nationwide that strongly believe the best treatment is no treatment but rather a “watch and wait” approach. Prostate cancer usually is slow growing and more than 70% of men who develop it are over 65.

The older a man is, the more likely he is to die of some other condition before his prostate cancer becomes a real threat. To reiterate, the American Cancer Society states, “at this time watchful waiting is a reasonable option for some men with slow growing cancers because it is not known whether active treatment such as surgery, radiation therapy or hormone therapy prolongs survival”. So what action can be taken? While prostate enlargement (BPH) is not related to prostate cancer, it can elevate PSA scores and can cause symptoms in 50% of men by age 80 and nearly all will show signs of BPH by age 85.

If you have early symptoms of BPH such as frequency of urination, a burning feeling after urination and the caliber of stream that isn’t what it used to be, getting up several times through the night and low back pain, taking a good prostate support formula will be your best treatment and prevention. Most men will notice a remarkable improvement within a few weeks. A good prostate support formula will provide relief for 80-90% of all men from these annoying symptoms.

But what about prostate cancer?

The best cure for prostate cancer is prevention. I’ll give you a complete supplement program for prevention but first what about PSA testing? “I don’t believe in screening for something when it’s too late. By the time cancer develops a positive mammography or a true high PSA are likely too late, or if fortunate, that particular cancer will not be a problem. It makes far more sense to prevent the problem in the first place. And there is clear data, prevention is possible”. Dr. Robert J. Rowen, MD, Second Opinion, Soundview Communications. My recommendation, based on research of several scientific studies, includes various nutritional supplements and herbal extracts.

Following are several very important studies that all men should be aware of. In 1966 Dr. Larry Clark of the University of Arizona published startling data suggesting that prostate cancer could be reduced by as much as an amazing 60% by supplemental yeast derived selenium, 200 mcg per day. Selenium is a powerful antioxidant and participates in key and crucial detoxification and free radical scavenging enzymes (80-90% of all disease is caused by free radical damage and inflammation).

Selenium is one of a number of antioxidants to prevent this free radical damage; In 1999 a New Zealand study published in the British Journal of Cancer documented a 40% lower incident of prostate cancer in men with the highest levels of omega-3 fatty acids EPA and DHA in their blood. These findings have been confirmed in other omega-3 fatty acid studies. Conversely, another published report documents a high level of omega-6 to omega-3 fatty acids in invasive prostate tissue samples. Taken together with recent reports on high levels of omega-6 fatty acids (soy, sunflower, safflower, peanut, corn and most vegetable oils) linked to breast cancer, a common thread emerges. The American diet is overwhelmed with omega-6 oils.

Excessive use of omega-6 fatty acids are cancer causing and also cause inflammation. Trans fatty acids from hydrogenated oils seriously add to the problem. There are other nutrients that have shown to reduce prostate-cancer risk. Vitamin E and lycopene have also shown to prevent prostate cancer. Lycopene is commonly found in tomatoes, especially cooked tomatoes. If you like spaghetti sauce or salsa, this is a great way to fight prostate cancer. While vitamin E, selenium, lycopene and omega-3 fatty acids are all great prostate supporting nutrients, through research I found a much more powerful combination of food grade molecules that can prevent and treat cancer.

Extensive research in the last few years has revealed that regular consumption of certain fruits and vegetables can reduce the risk of prostate cancer. Fruits and vegetables having the highest degree of prostate cancer protection are the following: grapes (resveratrol), garlic, tomatoes, hot peppers, turmeric (curcumin), ginger, berries, milk thistle, cloves and fennel. These foods are protective because they are extremely active and excellent antioxidants. My favorite is turmeric (curcumin) because not only is it an antioxidant, it is also an anti-inflammatory agent. When it has this dual effect it is many times more potent than other types of food. In the United States there is 30 times more prostate cancers diagnosed than there are in India where turmeric is consumed liberally in most of the Indian dishes. Cancer does not begin shortly before it’s diagnosed.

The origin of cancer may be years or decades in the process before it is even diagnosed as such. It is a multi-step process that goes through various phases such as cellular damage and transformation and culminates in the acquisition of invasive potential angiogenic properties and establishment of metastatic lesions. This process, and probably rightly so for all cancers, can be activated by any one of the various environmental carcinogens (cancer causing); all forms of tobacco products, industrial emissions, gasoline vapors, inflammatory agents, food coloring and preservatives, excessive UV rays, alcohol, hair dyes, cleaning products and drugs.

The multi-step process of these cancer causing compounds progress in three stages; tumor initiation, promotion and progression phases. A powerful antioxidant/anti-inflammatory can prevent most if not all of the damaging effects when taken on a daily basis. Several population based studies indicate that people in Southeast Asian countries have a much lower risk of acquiring colon, gastrointestinal, prostate, breast and other cancers when compared to their western counterparts. It is very likely that constituents of their diet such as garlic, ginger, turmeric, onion, tomatoes, cruciferous vegetables, chili’s and green tea play an important role in their ability to avoid these cancers.

These foods, or key active extracts from these foods, are known to block the NF-kB activation process. Also, several phytochemicals such as curcumin, resveratrol and green tea catechins have been shown to suppress AP-1. Several chemopreventative phytochemicals including curcumin, resveratrol and green tea have been recently shown to be powerful inhibitors of several growth factor receptors including EGFR. Curcumin also possesses the capacity to inhibit the activation of the EGF-Receptor indicating that it has the potential to break the autocrine loops that are established in several advanced cancers.

Studies also suggest that curcumin, resveratrol and green tea can actually be used as safe, non-toxic treatments in drug resistant cancers. These natural phytochemicals (food grade) can help fight certain cancers thereby requiring a smaller dose of drug chemotherapy. They also can protect the body from the damages of drug chemotherapy and radiation. “This mini review presents evidence that chemopreventative agents, curcumin, green tea and resveratrol, can be used not just to prevent cancer but also to treat cancer. Because of their pharmacological safety, most chemopreventative agents can be used in combination with drug chemotherapeutic agents to enhance the affect at lower doses and thus minimize chemotherapy- induced toxicity. Because cancer is primarily a disease of old age, less toxic therapy is a major priority. This review reveals that molecular targets of chemopreventative agents are similar to those currently being used for the treatment of cancer. Tumor cells use multiple cell survival pathways to prevail and thus agents that can suppress multiple pathways have great potential for the treatment of cancer”1,2. Curcumin, resveratrol and green tea were as effective in preventing and treating certain cancers based on lab and animal studies. There have been approximately 20 human positive studies but much more needs to be done.

From the research that I have done, I am convinced sufficiently enough to take many of these compounds as a preventative of cancer. These compounds are completely safe and non-toxic even in high doses. What does one have to lose? Why not take the positive preventative measure? –Compliments of Terry Naturally

Ref: 1. Role of chemopreventaive agents in cancer therapy. Comprehensive Cancer Center Our Lady of Mercy Medical Center, New York Medical College, Bronx New York

2. Cytokine Research Section, Department of Bioimmuno Therapy, University of Texas, M.D Anderson Cancer Center, Houston Texas

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Third- The Science (Putting It All Together) Boswellia & Inflammation

Date: April 03, 2008 12:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Third- The Science (Putting It All Together) Boswellia & Inflammation

Frankincense has traditionally been used in Ayurvedic medicine for centuries, and is even mentioned in the Bible. The trunk exudes a resin containing mono- and sesquiterpenes that possess powerful anti-inflammatory properties. They are also well known antiseptics and astringents, and support the immune and respiratory systems.

These terpenes are commonly referred to as boswellian acids, and consist of a carboxylated pentacyclic triterpene with at least one more functional group. Both the alpha and beta acid have a hydroxyl (-OH) grouping, and there are also the acetyl (CH3CO-) equivalents with an acetyl group replacing the OH. There are other so-called-boswellian acids, and it is believed that they all play a part in the anti-inflammatory properties of the resin.

The acetyl derivatives are thought to be involved in the death of some cancer cells, particularly those involve in brain and colon tumors, and also leukemia. The way in which they achieve this appears to be a programmed progression that ends with the dying out of the cells rather than a violently destructive mechanism, which lends credence to the Ayurvedic belief that the treatment is a natural one designed by nature.

The anti-inflammatory properties of the acetyl triterpenes are due to their effect on leukotrienes that sustain the inflammatory reactions of many allergic reactions and also of asthma. They appear to inhibit the enzyme elastase in leukocytes; this is a crucial enzyme in the production of the chemicals that promote inflammation.

It has been established that the inflammatory response of the immune system is due to the action of specific enzymes, so it stands to reason that if you can inhibit these enzymes, then you will also inhibit the immune response to specific initiators and so reduce the pain involved. Bosellian acid in the form of triterpenes appears to contain these inhibitors, and this would appear to explain its effectiveness. Pinene and phellandrene are among the terpenes isolated from Boswellia.

A standardised dose of 60% - 65% of Bosellian acids is generally used, so if you are purchasing Boswellia this is what you should be looking for. Keep in mind that it is intended to treat inflammation, ands that inflammation is an indicator that something with your body is not quite right. Therefore, while inflammation is painful, and Boswellia may help, you should also treat the cause of the inflammation by treating the immune system.

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Boost Skin And Joint Health With Natural Supplements

Date: January 19, 2008 10:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Skin And Joint Health With Natural Supplements

A lot of health conscious adults are now attempting to keep a youthful appearance for as long as possible by exercising, taking growth hormone enhances, and using expensive cosmetics. However, studies have proven that the major signs of aging in the skin, joints, and eyes occur due to a progressive collagen and hyaluronic acid degradation in our tissues. Researchers believe that supplementation of these key nutrients can actually reverse sings of aging.

Normal functioning of the skin requires that there be normal physiological substances in and around the skin cells. Of the many substances that are required for normal functioning, collagen is one of the most important. Collagen provides structural support to skin, which helps to maintain skin tone, subtleness and elasticity. All of these give the skin its amazing beauty. Without enough collagen, our body would actually lose any connective properties and its ability to hold together, causing the sagging and wrinkles that are associated with age.

Hyaluronic acid is also a vital component of the skin's structure. HA is a big part of the space between living cells and is also present in both the dermis and epidermis, where it allows skin to retain moisture and acts as a lubricant between the collagen matrix of the skin. Younger looking skin typically has higher levels of HA, but it has been observed that hyaluronic acid content declines as we age, most dramatically after the age of 50. Most people after the age of 40 have already lost a lot of HA and may require supplementation. High concentrations of hyaluronic acid and chondroitin sulfate are able to reach the corium layers of the epidermis and provide cellar level nourishment to the skin. This then reveals a more vibrant and younger looking complexion.

Doctors believe that osteoarthritis affects more than 20 million Americans, with that number reaching 40 million by the year 2020. Some doctors believe we're headed for an epidemic of degenerative joint disease. Osteoarthritis is a degenerative joint condition marked by the erosion of the cartilage at the ends of the bones. Cartilage is the shock absorber of the joint, with regular wear and tear on the joints eventually softening, fraying, and thinning the substance. Other things that can cause cartilage degradation and osteoarthritis have recently been identified by scientists, including: weak quadriceps muscles, eroding cartilage, and changes in bone structure. Certain genes also play a role in predetermining cartilage status, and left untreated and unchecked, this can become extremely debilitating.

Since normal joint function requires healthy cartilage and bones, one of the most important substances required for the normal functioning of joints is collagen. As we age, it has been observed that there is a decrease in the production and concentration of collagen in the joints. The lack of this vital structure leads to joint pain and inflammation. Common treatments today include the prolonged use of painkillers and anti-inflammatory drugs, steroids, NSAIDs and COX-2 inhibitors which temporarily relieve pain and cover up the symptoms while the disease moves further. More often, these treatments worsen the condition instead of helping it due to their harmful side effects. A natural supplement containing Collagen II can not only halt the progression of arthritis but can also improve the condition and provide relief to sufferers.

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Which Form Of Calcium Is Best For You?

Date: January 15, 2008 05:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Which Form Of Calcium Is Best For You?

There is no warning signal that lets you know if you have a calcium deficiency. Actually, a calcium deficiency is usually undetectable until damage that is irreversible has already occurred. A calcium deficiency is extremely hard to detect because the calcium level in the blood may seem to be normal, even if extreme cases of deficiency are actually occurring. This is because the body has a calcium bank, which can be found in teeth and bones. Calcium is needed in order to control muscular contractions such as the heart, blood-clotting, transmission of nerve impulses, and other requirements which take priority.

You may not know for sure whether you have calcium deficiency until you experience loose teeth, receding gums, or a bone fracture. At this point you will realize how brittle and chalky your bones have become. There is no known cure for osteoporosis, and it seems to be affecting people at younger ages more and more. The progression towards this illness takes years, but it is going on unnoticed in a great percentage of our population right as we speak.

There are many reasons why calcium deficiency is so widespread. First, calcium is not easily absorbed, as no more than 10-20% of what is found in foods is actually consumed and metabolized. This is because a meal that is high in fats can form insoluble calcium soaps which cause calcium to pass through the system without being absorbed. Also, the calcium in certain vegetables can actually be inhibited from releasing by oxalates that are found naturally in foods such as rhubarb, kale, spinach, broccoli, grains, and cereals.

Furthermore, vitamins A and D must be present in the body in order for absorption to occur. Additionally, calcium requires an acid environment for absorption, which is a huge problem for older people who have less production of digestive acids. More so, amino acids are needed for the formation of calcium-amino acid complexes and magnesium and phosphorus must be present in a precise ratio’s. Without all of these factors, you can lose a lot of the benefit, no matter how much calcium you are taking in.

A great variety of calcium supplements can be found in your health food store. These supplements can range from a simple calcium carbonate to bone meal, dicalcium phosphate, dolomite, calcium lactate, calcium gluconate, and many others. Although they all contain calcium, they vary in the amount of actual calcium content from 40% in calcium carbonate to 9% in calcium gluconate. Calcium carbonate has the highest percentage calcium per gram, but it acts as an antacid which makes this supplement somewhat useless since calcium can only be absorbed in an acid environment.

Acid breaks down the bonds between the calcium element and its bonding partner like carbonate or amino acid chelate. Calcium Carbonate has a carbon bond the strongest bond of its kind; this makes it extremely unwise for those people who are older or suffer from a digestive acid deficiency. Calcium carbonate that is derived from oyster shells is no different from any other form. However, oyster shells carry an additional risk of being contaminated with naturally occurring heavy metals found in the oyster bed environment. Calcium phosphate is probably the best source of calcium, since the principle calcium in the body is actually calcium hydrogen phosphate which is easy to digest.

Whether you choose calcium carbonate or calcium citrate, ask your local health food store which calcium is best for you depending on your age and whether you have a digestion disorder or not. With poor diets and lack of exercise, calcium supplementation is a must for most people. Have you had your calcium today?

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Active Coenzyme Q10

Date: July 07, 2007 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Active Coenzyme Q10

Active CoQ10

 

The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.

In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. What is ubiquinol? Is it the same or different from CoQ10?

A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.

 

Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?

A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.

So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.

 

Q. What are the health benefits of CoQ10 and Ubiquinol?

A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.

In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.

 

Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?

A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.

 

Q. How might ubiquinol be important for the heart?

A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.S. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment. Since ubiquinol is the active form of CoQ10, it may be able to overcome the hurdles to providing maximum impact, most importantly, age and genetic related inefficiencies in converting CoQ10 to active CoQ10 (Ubiquinol).

 

And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.

The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.

Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.

The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.

Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.

 

Q. What have been the results of research studies with Ubiquinol?

A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.

Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Should I take CoQ10 or ubiquinol? How much should I take?

A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.

Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.

 

Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological diseases, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagines. The more we study this naturally occurring compound, the more benefits we find. And with this new ability to provide CoQ10 in its active form, ubiquinol, for the first time, even greater benefits may be derived.

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Memory And Focus

Date: May 08, 2007 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Memory And Focus

Memory & Focus

 

Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.

This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.

The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.

In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.

 

Q. What is the difference between age related memory decline and dementia?

A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.

While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.

After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.

Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.

While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.

 

Q. Are any types of memory and focus loss reversible?

A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.

Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.

A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.

 

Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?

A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..

Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.

 

Q. How can nutritional supplements improve memory and focus?

A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.

One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.

Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.

In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.

 

Q. Hoe does Bacopa monnieri help memory and focus?

A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in India and has a long history as a natural medicine. In a recent study, bacopa was compared to a placebo in its effect on memory. Adults between the ages of 40 and 65 were divided into 2 groups. Half got the bacopa and half got a placebo. Researchers, who didn’t k now which patients got the bacopa, tested both groups’ memory before the study, at three months, and when the study ended six weeks later. The results showed the group taking the bacopa extract was able to remember new information much better than the group taking the placebo.

 

Q. How does alpha lipoic acid help memory and focus?

A. Alpha lipoic acid (ALA) is a vitamin-like coenzyme that prevents memory and focus problems we might have later on. ALA is an incredibly powerful antioxidant that works especially well with other antioxidants. An antioxidant’s job is to disarm damaging free radicals, those naturally occurring molecules that damage cells and cause disease. ALA has potent antioxidant action in almost all the tissues of the body, helps generate energy from food an oxygen, can get directly to the nerves, and plays an important role in the “antioxidant network”.

Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly, ALA’s effect in the illness has been studied extensively. Researchers have learned that ALA not only prevents free radical damage in Alzheimer’s disease, but also regulates protective chemicals in the brain that help improve symptoms.

In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given ALA supplements for an average of 11 months. At the end of the study, the participants were tested again. The results showed that every person had higher scores on the thought and memory tests than they had at the beginning.

ALA is unique among antioxidants, as it can neutralize free radicals in both the fat and the water of cells. In contrast, the well known vitamin C is only water-soluble, while the popular antioxidant vitamin E is only soluble in fat. Because ALA is easily absorbed, enters cells and tissues in a highly usable form, performs a variety of antioxidant actions (including rejuvenation of other antioxidants), and is both fat and water soluble, many researchers label ALA an “ideal antioxidant”.

 

Q. How do vitamins B12 and B6 help memory and focus?

A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.

Like ALA, vitamins B6 and B12 help prevent memory and focus problems further on down the road. One important recent discovery is the role of homocysteine in brain diseases. These important B vitamins can reduce homocysteine, an amino acid (the building blocks of protein) that is produced in the human body. Homocysteine irritate s blood vessels, makes it easier for blood to clot, and can cause cholesterol to become more harmful.

Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.

Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.

 

Q. What about folic acid?

A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.

An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.

Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.

 

Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?

A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.

Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.

It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.

 

Conclusion

Dealing with age-related memory loss may be both frustrating and frightening. As the population of America gets older, dementia is continuing to affect a larger proportion of society. Prevention of these devastating diseases has become increasingly important.

In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and ALA can improve age-related memory loss and potentially prevent the development of Alzheimer’s disease and other dementias as we age.

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CoQ10 for Heart Health

Date: March 28, 2007 12:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10 for Heart Health

CoQ10 for Heart Health

 

More than 40% of all deaths in the U.S. are from cardiovascular disease (CVD). You have a greater chance of dying from heart disease than from cancer, AIDS, diabetes, and accidents combined. More than 2,600 Americans die each day of CVD – an average of 1 death every 33 seconds. One in 5 men and women have some form of CVD. If all forms of major CVD were eliminated, life expectancy would rise by almost 7 years.

One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. For what health conditions is CoQ10 used?

A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.

 

Q. Why is CoQ10 especially important to heart health?

A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.

 

Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.

 

Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.

In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.

 

Q. What studies support this fact?

A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

 

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

 

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.s. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment.

 

Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?

A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.

 

The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

 

Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.

 

Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?

A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.

 

While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?

A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:

 

1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.

 

2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.

 

3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at Massachusetts General Hospital and Harvard Medical School.

 

4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.

 

Q. How much CoQ10 should I take?

A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.

 

CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

 

Q. What are some other heart-friendly supplements?

A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.

 

Q. What supplements support healthy blood pressure and cholesterol?

A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.

 

Conclusion

CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.

The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.

Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.

 

 

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Glucosamine Sulfate and Chondroitin Sulfate

Date: March 28, 2007 11:10 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine Sulfate and Chondroitin Sulfate

Glucosamine Sulfate and Chondroitin Sulfate

Osteoarthritis is the most prevalent form of arthritis in the U.S., according to the Arthritis Foundation. One-third of all American adults have X-ray evidence of osteoarthritis of the hand, foot, knee, or hip. Osteoarthritis is responsible for more than 7 million physician visits per year and is second only to cardiovascular disease as the cause of chronic disability in adults. As Baby Boomers age, the number of people suffering from osteoarthritis is expected to rapidly increase in the next 10 years.

While osteoarthritis research ahs led to the development of promising new prescription and over-the-counter medications aimed at reducing pain, none has created the excitement of glucosamine sulfate (GS), which actually addresses the underlying joint destruction.

Q. What is osteoarthritis?

A. Osteoarthritis is a complex, metabolic disorder of the cartilage and bones of certain joints. However, to fully understand how osteoarthritis develops, we need to understand how joints work.

A joint is formed when two or more bones are brought together and held in place by muscles and tendons. Some joints have very little range of movement, such as the joints of the ribs, while others have much more range of movement. Hips, knees, elbows, writs, and thumbs are termed synovial joints, and have the greatest range of movement and mobility of human joints. To allow such mobility, synovial joints have a unique structure.

The bones that form synovial joints are covered with cartilage. Tough fibrous tissue encloses the area between the bone ends and is called the joint capsule. The joint cavity within the capsule is lined with an inner membrane, called synovial membrane. The membrane secretes synovial fluid, a thick, slippery fluid that fills the small space around and between the two bones. This fluid contains many substances that lubricate the joint and ease movement.

The cartilage of synovial joints serves two very important functions. First, it provides a remarkably smooth weight-bearing surface; synovial joints move easily. Secondly, synovial cartilage serves as a shock absorber, providing a soft, flexible foundation. Healthy cartilage absorbs the force of the energy, transmits the load to the bone, and distributes the mechanical stress created by joint movement.

Synovial joints function under almost continual mechanical stress. A joint’s ability to withstand or resist this stress is a reflection of its health. When the mechanical stress is too great or the joint’s ability to resist this stress is compromised, physical changes occur in the cartilage covering the bones.

Cartilage is a tough, elastic tissue, comprised mostly of water, collagen, and complex proteins called proteoglycans. In osteoarthritis, the cartilage starts to weaken, becomes frayed, and eventually breaks down. This exposes the bones of the joint, which then rub together. A gritty feeling and grinding sound may occur when an osteoarthritic joint is bent and flexed. As osteoarthritis progresses, bits of bone and cartilage often break off and float inside the joint space. The bones may enlarge, causing the joint to lose its normal shape. Tiny bone spurs may grow on the joints’ sides and edges. These physical changes in the diseased joint are responsible for progressive damage and continual pain.

People with osteoarthritis most frequently describe their pain as deep and aching. The pain not only is felt in the affected joint but may also be present in the surrounding and supporting muscles. Joint inflammation also may occur, increasing the already considerable discomfort. Joint stiffness is another unfortunate component of osteoarthritis. Exercising the joint most often results in increased pain; however, stiffness tends to follow periods of inactivity. Humid weather often makes all osteoarthritis symptoms worse. As the disease progresses, the pain may occur even when the joint is at rest, creating sleepless nights and miserable days.

Q. What causes osteoarthritis?

A. Osteoarthritis’ exact cause remains unknown. Researchers know aging doesn’t appear to cause osteoarthritis. Cartilage in people with the disease show many destructive changes not seen in older persons without the disease. However, certain conditions do seem to trigger osteoarthritis or make it worse.

Some families seem to have a lot of osteoarthritis, pointing to a genetic factor. This is most commonly seen in people who have osteoarthritis of the hands. Repeated trauma can contribute to osteoarthritis, too. Athletes, extremely active people, and individuals who have physically demanding jobs often develop the disease. Persons who have certain bone disorders are more prone to osteoarthritis due to the continuous, uneven stress in their hips and knees.

Obesity also is a risk factor for the disease. In overweight women, osteoarthritis of the knee is fairly common. Excess pounds also may have a direct metabolic effect on cartilage beyond the effects of increased joint stress. Obese people also often have m ore dense bones. Research has shown dense bones may provide less shock-absorbing function than thinner bones, allowing more direct trauma to the cartilage.

Q. Can osteoarthritis be prevented?

A. While there is currently no sure way to prevent osteoarthritis or slow its progression, some lifestyle changes may reduce or delay symptoms. The Arthritis Foundation states that maintaining a healthy weight, losing weight if needed, and regular exercise are effective osteoarthritis prevention measures.

Optimal calcium intake in younger years is vital to ensure a healthy aging skeletal system. Vitamins A, C, D, and E have been studied for their role in osteoarthritis prevention. These vitamins also have shown benefit in individuals who have osteoarthritis.

Q. What treatments are available for osteoarthritis?

A. The goal of treatment is to reduce or relieve pain, maintain or improve movement, and minimize any potential permanent disability. Typically, non-steroidal anti-inflammatory drugs or NSAIDs (pronounced “n-sayds”) such as aspirin and ibuprofen are used for pain and inflammation relief. These medications are effective in treating only the pain of osteoarthritis.

These medications have many side effects, some of which are serious. NSAID-induced gastrointestinal complications cause more than 100,000 hospitalizations and nearly 16,500 deaths annually in the U.S. Aspirin can cause an extremely annoying and continual ringing in the ears. NSAIDs frequently cause damage to the stomach lining, which can produce uncomfortable heartburn and abdominal pain. Continued NSAID use may lead to the development of stomach ulcers. NSAID-related ulcers can perforate the stomach lining and cause life-threatening bleeding. Most NSAIDs also interfere with blood clotting and may cause kidney damage. When older persons take NSAIDs, dizziness, drowsiness, memory loss, and decreased attention span may occur.

Acetaminophen (Tylenol and similar medications) is similar to aspirin and other NSAIDs in its pain-relief abilities. However, acetaminophen doesn’t reduce inflammation. And while acetaminophen doesn’t have the same side effects of aspirin and other NSAIDs, if large doses are taken, liver damage can occur.

Newer medications called COX-2 inhibitors provide both pain relief and reduce inflammation without the many side effects of acetaminophen, aspirin, and other NSAIDs. More recent research has indicated that, in certain situations. COX02 inhibitors also can cause stomach lining damage and bleeding. While aspirin, NSAIDs, and COX-2 inhibitors may reduce osteoarthritis pain, they do nothing to stop or slow down cartilage deterioration. In other words, these medications have no effect on the disease itself.

That is why many believe glucosamine sulfate (GS) and chondroitin sulfate (CS) are preferable to pain relievers and anti-inflammatory medications in osteoarthritis treatment: they actually improve synovial joint health. And they do this without potentially life-threatening side effects.

Q. How do GS and CS work?

A. GS improves the health of joints affected by osteoarthritis. This supplement is so effective that even physicians who mostly rely on conventional medications routinely recommend it to their patients with osteoarthritis. In fact, GS is so good at treating osteoarthritis, many physicians use it for their own osteoarthritis joints.

There is even more good news. When glucosamine sulfate is combined with low-molecular weight CS, even greater benefits can be achieved. GS and CS are naturally occurring compounds found in human joints. The right GS/CS combination actually reverses damage in joints affected by osteoarthritis, in turn significantly reducing pain and stiffness.

Glucosamine occurs naturally in the body and is found in synovial fluid. Glucosamine is a basic building block for proteoglycans, is a basic building block for proteoglycans, one of the important compounds of synovial cartilage. It also is required for the formation of lubricants and protective agents for the joints.

In Europe, GS and CS have been used to treat osteoarthritis for more than 10 years. While persons with arthritis felt much better when they took GS and CS, no one really knew how these compounds worked. When European and American researchers first started to study glucosamine, they discovered GS can reduce synovial joint inflammation. This explains why people felt better after taking it.

Q. What has additional study of GS and CS revealed?

A. As the scientific study of GS progressed, researchers determined it can stimulate the growth of cartilage cells, inhibit proteoglycans breakdown, and rebuild cartilage damaged from osteoarthritis. In other words, GS does not simply make persons with osteoarthritis feel better; GS actually makes persons with osteoarthritis get better.

GS is the form of glucosamine used in research. It’s the sulfate salt of glucosamine and breaks down into glucosamine and sulfate ions in the body. The sulfate part of GS plays an important role in proteoglycans synthesis.

CS also provides cartilage strength and resilience. CS is an important component of the cartilage proteoglycans of synovial joints. Because CS helps the production of proteoglycans, researchers believe CS works in a similar nature to GS.

Q. Couldn’t GS and CS be taken on their own? Is there any benefit in taking them together?

A. Research has discovered GS and CS act synergistically (work well together) in improving joint health. Several studies have investigated this action and it’s recommended that GS and CD be taken together. However, there may be times when your healthcare practitioner may recommend using one or the other, but not both GS and CS together. Please follow their recommendations to obtain the best results for your own unique health concerns. Low-molecular weight chondroitin sulfate (CS) is the preferred CS form, and the form that has shown the most promise in studies.

Q. Why is it important to take low-molecular weight CS?

A. When CS was first studied, it was given to six healthy volunteers, six patients with rheumatoid arthritis, and six patients with osteoarthritis. Researchers then measured the levels of CS in all study subjects. They found no evidence of CS in any of the subjects. This single study led many physicians and scientists to believe CS can’t be absorbed, and was not an effective natural treatment.

However, several other studies in healthy volunteers have reported CS can be absorbed. The distinct difference for these findings is thought to be associated with the types of CS used in the studies. Some forms are much more absorbable that others. This was demonstrated in a recent study using CS with lower molecular weight. A higher absorption is observed for low-molecular weight CS.

This means CS products with a low molecular weight may be better absorbed, allowing the CS to get into the bloodstream and the synovial fluid of joints where it’s needed.

Q. Are there other supplements that can help osteoarthritis?

A. Several vitamins, minerals, enzymes, and natural supplements have benefits for individuals with osteoarthritis. Proteolytic enzymes effectively offer relief of the pain, stiffness, and swelling of osteoarthritis.

Folic acid and vitamin B can reduce the number of tender joints and increase joint mobility. Vitamins C, D, and E not only may prevent osteoarthritis, but inhibit the disease’s progression. Niacinamide improves joint function, range of motion, and muscle strength. Clinical studies using the herb Boswellia serrata have yielded good results in osteoarthritis.

Application of ointments on osteoarthritic joints may be helpful in reducing pain and stiffness. Menthol-based preparations can provide soothing relief to painful joints. Capsaicin ointments and gel made for cayenne pepper also are very beneficial. When applied to the skin, capsaicin first stimulates, then blocks, nerve fibers that transmit pain messages. Capsaicin depletes nerve fibers of a neurotransmitter called substance P. This neurotransmitter transmits pain messages and activates inflammation in osteoarthritis. Capsaicin ointment is very effective in relieving osteoarthritis pain in many individuals.

Q. Is there anything else I can do for joint pain and stiffness?

A. When osteoarthritis occurs in the hands, use of a paraffin dip can be very comforting. A licensed health care practitioner can provide information about how to safely use paraffin dips at home.

Exercise is an excellent way to keep joints mobile, decrease pain, and increase body strength, too. Water aerobics also can reduce the pressure and stress on joints.

The Arthritis Foundation strongly suggests making movement an integral part of your life. When you’re in less pain and have more energy, more range-of-motion, and a better outlook on life, you’ll reduce stress and be a much healthier person despite your osteoarthritis.

One important last thought

When we don’t feel well, we sometimes have a tendency to self-diagnose. If you haven’t been evaluated by a licensed health care practitioner for your joint pain and stiffness, you need to do so. These symptoms may be caused by other illnesses and may require much different treatment. Only licensed health care practitioner can provide a certain diagnosis of osteoarthritis.

Conclusion

Osteoarthritis may be a part of life for many of us as we age; however, constant pain and stiffness need not be. GS combined with absorbable CS can actually improve damage in joints affected by osteoarthritis and significantly reduce pain and stiffness. And it can be an empowering way to improve your health.

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Neurological Health and CoQ10

Date: February 25, 2007 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Neurological Health and CoQ10

Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.

Q. Isn’t CoQ10 a supplement for heart health?

A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.

Q. How does CoQ10 affect brain health?

A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.

The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.

The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.

Q. What is the blood-brain barrier and why is it important?

A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.

Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.

Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.

Q. If CoQ10 is made in the body, why take supplements?

A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.

Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.

Q. How does CoQ10 help people with Parkinson’s disease?

A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.

A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.

Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.

The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.

The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.

Q. What were the results of clinical research on Huntington’s Disease?

A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.

Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.

Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.

Q. What other diseases could benefit from CoQ10 supplementation?

A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.

In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.

ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.

Q. Can taking CoQ10 prevent neurodegenerative disease?

A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.

Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.

Q. How much CoQ10 should I take?

A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.

CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

Q. What should I look for in a CoQ10 supplement?

A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.

Conclusion

CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.

All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.

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Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.

Date: November 09, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.

For some people the constant tingling in their feet is the worst part. Others feel like their feet are being stabbed or burned, or that their extremities are simply lifeless. All these folks suffer from peripheral neuropathy, nerve damage that afflicts nearly 30% of people with diabetes aged 40 and older. And if the discomforting sensations are not enough, neuropathy can lead to falls, wounds that won’t heal, even amputation.

Untold numbers of individuals have been helped by alpha lipoic acid (ALA), a supplement that European practitioners have used as a standard neuropathy treatment for 30 years. ALA (also known as thioctic acid) assists in the chemical reaction that generates energy within cells. It serves as a universal antioxidant—a substance that can fight tissue-damaging free radicals in both the fatty watery parts of a cell-and helps the body create additional free radical fighters, such as glutathione. ALA can even help regenerate several other antioxidants, including coenzyme Q10 (CoQ10) and vitamins C and E.

Defying diabetes

People with diabetes need antioxidant protection as much as anyone. Fortunately for them, though, ALA fights this insidious disorder in many other ways.

Diabetes occurs when the body can no longer effectively use glucose (blood sugar), its main energy sources; ALA helps shepherd glucose out of the blood and into cells. It also interferes with glycosylation, a process in which glucose sticks to proteins such as the low-density lipoprotein (LDL) that carries cholesterol through the bloodstream. That’s important because this “sticky” LDL can adhere to arterial walls, creating a major risk factor for heart disease. ALA combined with exercise appears to make insulin, the hormone that controls glucose usage, more effective. What’s more, early research indicates that ALA can deflect another cardio hazard by interfering with the ability of salt to push blood pressure upward (molecular and Cellular Biology 12/03).

ALA Annotations – what is it? Alpha Lipoic acid, a substance the body creates naturally.

What it Does: ALA, a powerful antioxidant in its own right, plays a vital role in the creation and renewal of other antioxidants. It is used to treat peripheral neuropathy; nerve damage caused by diabetes, and is also under investigation for possible therapeutic effects in other disorders, including multiple sclerosis and age-related cognitive decline.

Diabetes doesn’t just attack the nerves and the heart—its effects are felt throughout the body. That’s why scientists are examining whether ALA can tackle other diabetic complications: in lab studies it has forestalled diabetes-related kidney and eye damage. (Check blood-sugar levels regularly when using ALA, especially if you’re taking other glucose regulators.)

Protecting Nerves

While diabetes is one of the most common causes of nervous system damage, it isn’t the only one. In test tube studies ALA has promoted chemical reactions that encourage neurons (nerve cells) to survive and grow; as a result some scientists believe this natural antioxidant may eventually play a role in treating degenerative nerve disorders. Such research is in its beginning stages, but the results are still intriguing. For example, in mice ALA has slowed progression of a disorder that mimics multiple sclerosis in human beings (Journal of Neuroimmunology 3/04) and improved age-related memory loss when used with N-acetyl-cysteine (NAC), another antioxidant supplement (Journal of Neurochemistry 3/03). A number of other conditions that become more common with age may also benefit from ALA, including arthritis and thinning skin.

If you suffer from both diabetes and the nerve damage it causes, ask your practitioner about ALA. It just may help your feet and the rest of you feel happy. –Lisa James

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The sunshine vitamin can impart an all-over healthy glow.

Date: September 18, 2006 03:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The sunshine vitamin can impart an all-over healthy glow.

When papers like the Los Angeles Times write articles with titles like “wonder Pill-really” about a seemingly ho-hum nutrient like vitamin D, attention must be paid. The attention is now forthcoming from researchers who are exploring this humble vitamin’s connection to an astonishingly wide spectrum of health issues. And these scientist are concerned that, dispite fortification of such common foods as milk, many people aren’t getting the D they need for optimal well-being.

Vitamin D generally recognized as calcium’s indispensable little helper, which makes it vital to maintaining bone health. But we now know that D’s benefits extend far beyond calcium control; it plays crucial roles in immunity, blood cell formation and hormone regulation.

Anti-Cancer D-Fense

Scientists believe that vitamin D helps cells differentiate, or mature into specialized roles each is meant to play. That’s important in cancer defense because malignant cells tend to be undifferentiated, primitive types given to reproducing uncontrollably. Cells, both malignant and healthy, have vitamin D receptors on their surface; when d binds to cancer cells, they stop growing.

This may help explain why men with low levels of vitamin D are particularly prone to dying of cancer and why higher rates of prostate cancer occur in climates where exposure to the sun-which powers D creation within the skin—is low. On a more positive note, investigators at the Moores UCSD Cancer Center of San Diego report that taking 1,000IU of vitamin D daily appears to drop the risk of developing breast, colon and ovarian cancer by up to 50% (American Assn for Cancer Research, Ninth Meeting). Other studies suggest that even after cancer develops, D may help hinder disease progression and enhance survival.

Vitamin D does a body good in a number of other ways. For example, the sunshine vitamin lights up both the immune system and production of insulin, the hormone that controls blood sugar. In one study women who took the amount of vitamin D generally found in multivitamins (400 IU) and had a 31% reduced fisk of dying from heart disease; in another, D from multivitamins dropped the risk of multiple sclerosis development by 40%. Supplements have also helped stroke victims avoid the muscular wasting that leaks to falls and fractures (Cerebrovascular Disease 7/05). Conversely, low D levels have been linked to poor lung function, unexplained muscle pain and increased obesity risk.

Widespread D-ficiency

Currently, the federal government recommends daily vitamin D intakes of 200IU for people under age 51, 400IU for those 51 – 70 and 600 IU for ages 71 and up. But many prominent scientists believe those levels are two low, especially since so many folks avoid sun exposure to cut skin cancer risk. “I’m 99% sure that vitamin D deficiency is becoming more common,” Harvard nutrition expert Dr. Walter Willett told the LA Times (06/12/06). Deficiencies are more likely among dark-colored individuals (whose skins do not make D effectively), vegans (who avoid dairy) and people with disorders that reduce intestinal absorption, such as Crohn’s disease. Higher dosages should always be taken under practitioner’s watchful eye, especially if a medical condition already exists.

No matter what health hazard you’re trying to illuminate, don’t hesitate to bask in the sunshine vitamin’s warm radiance. –Lisa James.

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Degenerative joint disease (osteoarthritis)

Date: August 24, 2006 03:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Degenerative joint disease (osteoarthritis)

Degenerative joint disease (osteoarthritis) damages or destroys cartilage and its supportive collagen structure. As many as 40 million Americans, including the majority of people over age fifty, are thought to suffer from some form of this disease. Primary osteoarthritis, the “wear and tear” form, is due to normal use and age-related causes. Secondary osteoarthritis results from repeated joint trauma, inherited predisposition, or previous inflammatory conditions. While non-steroidal anti-inflammatory drugs (NSAIDs) treat symptoms only, a natural, holistic approach strives to improve the environment of the cartilage and joint as a whole by providing protective and restorative nourishment, increased circulation, decreased inflammation and reduced free radical damage.

High levels of Glucosamine and Chondroitin Sulfate

Widely regarded as the first defense in protecting joints, glucosamine and Chondroitin sulfate have been shown to effectively control joint pain and slow down or reverse the progression of cartilage deterioration. The integrity of joint gliding surfaces as well as the health of tendons, ligaments, joint fluids, skin, bones, heart valves and virtually all structural elements in the body is dependent upon the proper synthesis and availability of proteoglycans, integral components of joint cartilage.

Glucosamine provides two components critical to the synthesis of proteoglycans: hyaluronic acid and glycosaminoglycans (GAGs).

Chondroitin sulfate represents an important group of GAGs. It is not a single compound, but rather a class of compounds with different molecular weights that each have specialized functions within the body.

Numerous studies have shown that long-term safety, reduction in pain and protection of cartilage with body chondroitin and glucosamine are comparable or superior to results obtained with NSAIDs.

MSM. (Methylsulfonylmethane) MSM is a rich source of sulfur, a mineral required for GAG synthesis. A preliminary study suggests that MSM may help reduce pain in persons with degenerative arthritis.

Gota Kola. (Centella asiatica) known to support collagen synthesis and stimulate GAG’s, Gota Kola has been used for many years in Europe to promote wound healing and blood vessel integrity. It also has been shown to improve circulation in small vessels.

Turmeric. (Curcuma longa) this saffron-colored root offers a wide range of benefits. It naturally inhibits the inflammatory COX-2 enzyme, reduces pain and is a potent antioxidant that protects the liver and other cells. High antioxidant diets may inhibit joint deterioration.

Bromelain. Derived from pineapple cores, Bromelain is most commonly used for healing soft tissue injuries and inflammation. It contains potent selective proteases (protein-digesting enzymes) and other substances which serve to block destruction of GAGs.

Trace Minerals. Micronutrients play many distinct roles in support of healthy joint connective tissue and joint cartilage matrix.

Black Pepper Extract. Bioperine is a highly concentrated extract (95% - 98% piperine) of black pepper. Used as a bioavailability enhancer, it has been shown to increase the absorption of vitamins, minerals and herbs.

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Fighting fat with fat makes sense with conjugated linoleic acid.

Date: April 03, 2006 04:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fighting fat with fat makes sense with conjugated linoleic acid.

Trimming flab away with CLA

Fighting fat with fat makes sense with conjugated linoleic acid.

Substances that enhance human health and well being can be discovered in all sorts of odd places. Take conjugated linoleic acid (CLA), for example. This unique fatty acid currently under intense study as an aid to help dieters reduce body fat—was first isolated from grilled ground beef in the early 1980’s by researchers at the University of Wisconsin. (CLA is also found in hamburger that ma actually help you slim down? Who knew?

What’s more, CLA (now generally derived from plant sources like safflower oil) also shows promise in two important areas. First, evidence suggests it can slow down some of the steps in cancer’s complex progression. In addition, CLA may help tame excess inflammation.

Fat City

When you take in more calories through food than you burn off through exercise, all those extra energy units have to go somewhere and if you’re like a lot of folks, they wind up being deposited into your fat cells. Not only are jam-packed fat cells responsible for the dreaded disappearing waistline effect, but they also promote unhealthy changes in blood pressure, cholesterol levels and other makers of possible hazards to your continued well-being.

CLA helps make life miserable for fat cells in several ways. First, it inhibits an enzyme called lipoprotein lipase that shuttles fat molecules from the blood stream into the cells. It encourages lipolysis, or the breakdown of fat that’s already in storage. Finally, in some studies CLA has shown an ability to actually encourage fat cells to commit a form of cellular suicide call apoptosis—which results in fewer places for fat to hide. At the same time, CLA promotes the transport of fat into exercising muscle cells, helping them to both burn off calories and become more toned (and shapely).

CLA Comments: What is it: a special form of linoleic acid, an essential fat: CLA is found naturally in diary foods.

What it does: CLA has shown an ability to help reduce body fat and increase muscle mass (When used as part of a healthy diet and exercise plan); it has also demonstrated cancer-fighting and immune enhancing effects.

While CLA is the subject of ongoing research, early human trials have produced promising results. In Norway, for example, scientists from five separate institutions teamed up for a study involving people who were healthy but over weight. For the first year some of the individuals took CLA while the others took placebo (look-alike) softgels that contained olive oil instead; in the second year, everyone took CLA. At the end of two years, all the people in this study showed significant reductions in body fat, body mass index (BMI), a standard measure of obesity, and weight(Journal of nutrition 4/05).

Extra Helpings

While battling the bulge is a major goal for many people, fending off cancer may just be America’s number one health concern. And here, too, CLA has come up big in a number of studies, such as a Swedish investigation that shows a link between high CLA intake and reduced colorectal cancer risk (American Journal of Clinical nutrition 10/05). In various lab studies CLA has been shown to interfere with tumor development and keep cancerous cells from spreading to nearby organs.

What’s more, CLA appears to regulate immunity by helping to strengthen the body’s natural defenses while protecting against the inflammatory damage the immune response can cause. That’s important because low-level inflammation has been linked to an ever-growing list of disorders, including cancer, cardiovascular disease and arthritis.

If you want to fight off both fat and cancer without eating a mountain of cheeseburgers, don’t have a cow. Turn to CLA instead.

--Lisa James.

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Glucosamine & Chondroitin - JOINT HEALTH

Date: December 22, 2005 09:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine & Chondroitin - JOINT HEALTH

• Supports Healthy Joint Structure and Function
• Supports Mobility and Ease of Movement

References:
1) Balch, James F. et. al. ; Prescription For Nutritional Healing 3 rd rd rdPrescription Edition Edition ; Avery; Penguin Putnam; 2000
2) Benedikt, H.; Glycosaminoglycans And Derivatives For Treatment Of Arthritis; Chiropractic Products, May 1997, pp. 92-95
3) Reginster, Jean Yves et. al.; Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial; The Lancet, 2001, Vol. 357, No. 9252 4) Bassleer, C. et. al.; Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro; Osteoarthritis and Cartilage, 1998, 6, 427-434
5) Drovanti, A. et. al.; Therapeutic Activity of Oral Glucosamine Sulfate in Osteoarthritis: A Placebo-Controlled, Double-Blind Investigation; Clinical Therapeutics, Vol. 3, No. 4, 1980, pp. 260-272
6) Morreale, P. et. al.; Comparison of the Antiinfl ammatory Effi cacy of Chondroitin Sulfate and Diclofenac Sodium in Patients with Knee Osteoarthritis; Journal of Rheumatology, 1996, 23:8, pp. 1385- 1391

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Vitaberry Plus + Super Fruit Antioxidant

Date: December 07, 2005 05:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitaberry Plus + Super Fruit Antioxidant

Vitaberry Plus +™ Super Fruit Antioxidant

By Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),
- Catalase (neutralizes peroxides),
- Functions similar to reduced Glutathione (GSH),
- Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent),
- Functions similar to Glutathione S-transferase (GST),
- Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/

ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697

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In men under 65, prostate surgery can save lives.

Date: July 27, 2005 03:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: In men under 65, prostate surgery can save lives.

10. In men under 65, prostate surgery can save lives.

When it comes to treating prostate cancer, one question prevails: To have surgery or not to have surgery? Since many cancers are slow growing, doctors often suggest that patients take a wait-and-see approach, opting to monitor tumor growth instead. While this gamble can pay off, those with faster-growing cancers may not be so fortunate. A new study, published in the New England Journal of Medicine, determined that when men under age 65 opt for surgery, the odds of surviving prostate cancer increase while chances of the cancer recurring decrease.

At a glance, the findings may seem to contradict research that urges men to watch and wait, but the study targeted patients with localized tumors large enough to be felt during a manual rectal exam. Following radical prostatectomy, when surgeons remove the prostate, surrounding tissue and lymph nodes, cancer was less likely to spread locally or to distant sites. After 10 years, 19.2% of the men in the surgery group had local progression, compared to 44.3% in the watchful waiting group. Among the surgery group, 15.2% experienced distant cancer progression, while 25.4% of those who eschewed surgery had their cancer spread.

Now that you know the ins and outs of this complex but treatable disease, there’s really no good excuse to avoid getting regular screenings and following prevention guidelines. Being proactive about your prostate could save your life.

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A healthy lifestyle may prevent prostate cancer recurrence.

Date: July 27, 2005 03:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: A healthy lifestyle may prevent prostate cancer recurrence.

6. A healthy lifestyle may prevent prostate cancer recurrence.

Based on a breakthrough study of 1,117 men with localized prostate cancer ( cancer that is confined with-in the prostate), researchers discovered that those who kept body weight down, exercised regularly to the point of sweating and underwent routine screenings were less likely to experience a cancer recurrence. Patients with a high risk of progression were more likely to be obese, exercise less than twice a week and avoid annual prostate screenings. The findings, published by the American Association for Cancer Research, are among the first to quantify the risk that lifestyle factors have on whether prostate cancer will recur in patients.

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Celadrin - Benefits

Date: July 27, 2005 11:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celadrin - Benefits

Benefits

Increased Range of Motion in Joints*

Research has shown that Celadrin can have an impact on improving the range of motion in joints. A placebo-controlled trial conducted in 2002 showed that those individuals taking a complex containing Celadrin for 2 months had a significant improvement in knee flexion (ability to bend the knee) over those taking a placebo.1 Another study conducted on Celadrin published in 2004 concluded that treatment “significantly increased physical performance (as measured by a variety of orthopedic tests)” in patients with compromised knee mobility. The study found that the subjects given Celadrin showed improvement in their ability to climb stairs, rise from a chair and walk, along with an improved sense of balance, strength and endurance.3

Maintains Joint Comfort*

The anti-inflammatory actions of Celadrin have been demonstrated by one double-blind, placebo controlled trial that showed Celadrin, when taken orally at recommended intake levels, decreased pain scores and increased walking distance compared to the group receiving placebo. The authors theorize that Celadrin may work by down-regulating the effect of certain precursors of the body’s inflammatory response.1

Safety

Suggested Adult Use: One capsule three times daily, with or without food.

Scientific References
1. Hesslink R Jr., et al. Cetylated fatty acids improve knee function in patients with osteoarthritis. J Rheumatology 2002;8:1708-1712.

2. Anonymous. Monograph: Glucosamine sulfate. Alt Med Review 1999;4:3;193-195.

3. Kraemer WJ, et al. Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis. J Rheumatology 2004;4:767-74.

4. Crolle G, D'Este E. Glucosamine sulphate for the management of arthrosis: a controlled clinical evaluation. Curr Med Res Opin 1980;7:104-109.

5. Rovati LC. Clinical research in osteoarthritis: design and results of short-term and long-term trials with disease modifying drugs. Int J Tissue React 1992;14:243-51. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below.

6. Bassleer C, et al. Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro. Osteoarthritis and Cartilage 1998;6:427-434. Med. 2002 Oct 14;162(18):2113-23.

7. Reginster JY, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomized, placebo-controlled clinical trial. Lancet 2001;357:251-56.

8. Macario, J. T., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68. 9. Kraemer WJ, et al. Effect of acetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis. J Rheumatol.2004 Apr;31(4):767-74. 10. Kraemer WJ,et al. Acetylated fatty acid topical cream with menthol reduces pain and improves functional performance in individuals with arthritis. J Strength Cond Res.2005 May;19(2):475-80.

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PROGESTERONE AND OSTEOPOROSIS

Date: July 25, 2005 10:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: PROGESTERONE AND OSTEOPOROSIS

PROGESTERONE AND OSTEOPOROSIS

At this writing, evidence points to the fact that natural progesterone may be even more effective in treating osteoporosis than estrogen replacement therapy. While this evidence is still in its initial stages, it is significant and must be considered. In 1981, Dr. John Lee conducted a landmark study evaluating the effectiveness of using natural progesterone for osteoporosis.20 His study indicated that it is the cessation of progesterone production in postmenopausal women which causes the development of osteoporosis. Contrary to current trends, progesterone replacement, not estrogen, in fact may be the answer to preventing and treating osteoporosis. Dr. Lee’s study has profound implications for all women.

In his practice, Dr. Lee applied a natural progesterone cream on one hundred postmenopausal women and eliminated their usual dose of oral Provera (a synthetic progestin). The majority of these women were in varying stages of osteoporosis. Each participant used the natural progesterone cream for several consecutive days each month over a period of three years. The results were dramatic, to say the least. In addition to preventing further height loss and eliminating aches and pains, the bone mineral density of the spine was preserved in 63 of the women. In other words, these women not only stopped the bone loss associated with osteoporosis but actually experienced an increase in bone mass which, in many cases was more dramatic than had been seen with other therapies. In addition, the incidence of bone fractures actually dropped to zero. Dr Lee’s study found that estrogen was not the panacea for bone density previously assumed. He discovered that the women who took estrogen in combination with the progesterone were not better off than those who took progesterone alone. What was even more impressive was discovering that osteoporosis is a reversible condition with progesterone therapy. Concerning the use of progesterone for osteoporosis, Dr. Lee writes:

. . . when my 40 year old housewives had become 60-year olds with osteoporosis and I learned of transdermal natural progesterone (being sold as a skin moisturizer), I started adding it to my therapeutic regimen for osteoporosis, at first only to those for whom estrogen was contraindicated. To my surprise, serial bone mineral density tests showed a significant rise without a hint of side effects. With this obvious success, my use of natural progesterone spread to osteoporosis patients who were not doing all that well on estrogen alone. Again, it proved successful.21

Apparently, women who had the lowest bone densities experienced the greatest increases, implying that age and the progression of the diseases does not affect the beneficial therapeutic action of natural progesterone.

This study is profoundly significant in that it strongly suggests that women who take estrogen to prevent or treat osteoporosis may be better off using natural progesterone. As a result of Lee’s findings, several physicians began to use natural progesterone cream for their pre- and postmenopausal patients.

The most striking implication of Dr. Lee’s work with natural progesterone is that contrary to current medical opinion, osteoporosis may be more a manifestation of a progesterone deficiency than a lack of estrogen. In addition, the disease may be initiated long before menopause when estrogen levels are still high.22 Moreover, continued estrogen therapy for women with osteoporosis often caps out whereas progesterone therapy continually promotes the production of new bone.23 Dr. C. Norman Shealy, M.D. states: I believe that natural progesterone cream derived from wild yam extract should be used by almost every mature adult . . . The most common cause of death in elderly women is from the complications of fracture of the hip from osteoporosis. Such fractures are also remarkably common in men. I believe that progesterone cream could do more to preserve health and well-being in elderly people than all the drugs in the world.24

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Modified Citrus Pectin (MCP)...

Date: June 21, 2005 05:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Modified Citrus Pectin (MCP)...

Modified Citrus Pectin

By Isaac Eliaz, M.D.

Modified citrus pectin (MCP) is an essential nutrient for cancer prevention and treatment. It directly attacks cancer, thereby reducing the disease, but also has properties that enhance overall health. A true super nutrient! Let me explain how it can do all this.

Characteristics of Cancer Cells

Cancer cells are different from normal cells in a number of ways. One difference is they way they "look." All cells have a variety of molecules on their surface, which allow them to communicate with each other and their environment:

* They are receptors for neurotransmitters or hormones.

* They are markers that identify the type of cell.

* They are "hands" that let the cell stick in place or move around.

Cancer cells have odd amounts or unusual molecular markers on their surface, which allow white blood cells to recognize the cells as cancerous and kill them. One type of molecule cancer cells have in excess is galectin-3. Galectin-3 molecules function as "hands" and help cancer spread. First, they are important in reaching out and stimulating growth of new blood vessels; this allows the cancer to obtain the blood flow and nutrients it needs to grow out of control. Second, galectins allow cells that break off from the primary tumor to clump together in the blood stream, enabling them to move to new sites. Third, the galectin hand can grab hold of the new location and complete the metastasis, or spread, of the cancer.

MCP Blocks the Spread and Growth of Cancer Cells

Modified citrus pectin is a natural substance that can bind to galectin molecules and block their spread and growth. Early research on prostate cancer showed that oral administration of MCP to rodents resulted in a dramatic reduction in prostate cancer metastasis to the lungs. More recent research by the same scientists extended MCP protection to breast and colon cancer, and showed that MCP blocks primary tumor growth and formation of new blood vessels.

Successful Clinical Trial

A commercially available form of modified citrus pectin was developed in response to the positive animal studies and tested in men with prostate cancer. A pilot trial using MCP at 15 grams a day and a subsequent phase II trial both showed that MCP slows prostate cancer progression, as evidenced by a reduction in the rate of PSA rise. PSA (prostate-specific antigen) is a protein made by the prostate gland; elevated PSA blood levels may indicate prostate cancer. The phase II trial, published in Prostate Cancer and Prostatic Diseases (Dec 2003), involved men who at first experienced successful primary conventional treatment; subsequently their PSA again began to climb, representing cancer recurrence. Seventy percent of these men showed a significant reduction in the rise of their PSA climb! Because of the mechanism of action, it is expected people with other cancers (leukemia, breast, colon, lung, nasopharyngeal, brain, lymphoma, melanoma and others that express galectin molecules) also would benefit from MCP.

MCP Chelates and Removes Toxic Metals

Heavy metals, in conjunction with environmental toxins and xenoestrogens, constitute a dangerous insult to the body through DNA damage, hormonal modulation, immune suppression, oxidative stress, and hyper inflammation. The metal chelation properties of MCP (Eliaz, U.S. patent #6,462,029) have been confirmed in a recent pilot trial. In healthy individuals, MCP increased urinary excretion of the toxic metals mercury, cadmium, arsenic and lead. In addition, longterm administration of MCP has been shown to reduce the body burden of heavy metals such as mercury, arsenic, lead, and nickel. MCP's ability to remove heavy metals and environmental toxins on an ongoing basis may significantly benefit people with cancer and other diseases involving immune dysfunction.

Clinically Validated MCP

Only one form of MCP has been validated in human clinical trials. This is important since no other MCP on the market matches the chemical specifications of the clinically validated product. If the molecular weight of MCP is too high it can't be absorbed into the bloodstream. If it is too low it won't effectively block galectin sites. Another property, the degree of esterification, must be below 5% for optimal binding. The most effective specifications were defined by cell culture studies and remain a trade secret. If you want the effects seen in the clinical studies, you must take the preparation used in those studies, at the recommended dose of 15grams/day.

The Use of Modified Citrus Pectin

MCP Application Use (Take on an empty stomach) Active Cancer 15 grams/day (5 grams, three times a day) Biopsy 15 grams/day (5 grams, three times a day) Take one week before procedure and two weeks after. Heavy Metal Chelation High body burden levels: 15 grams/day (5 grams, three times a day) Lower levels: 15 grams/day for 5 days a month, 5 grams/day the rest of the month Cancer Prevention 5 grams/day ongoing

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Vitanet ®

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Fats: The Good, the Bad, the Ugly

Date: June 14, 2005 11:18 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fats: The Good, the Bad, the Ugly

Fats: The Good, the Bad, the Ugly by Thomas Sherman Energy Times, October 15, 2004

We need fat to absorb vitamins, to keep our brains sharp, to survive. But not all fats are our friends. Find out which ones are the heroes and the villains in your diet.

In a lot of cases health fads don't live up to their hype. But the case for consuming more good fats-the omega-3 fatty acids found primarily in fish, flax and hemp oils-is strong and growing stronger. As a nation we eat too little of these good fats, and our health would improve greatly if we relied a little less on the bad saturated fat in burgers, skipped the ugly trans fats in fries and indulged in more salmon and other seafoods.

Fish and the Heart

Need proof? A wealth of research supports fish oil's desirable effects, especially on heart health. While many people believe that heart disease is primarily a problem for men, women who have passed through menopause are just as susceptible to heart problems.

" [Our] findings suggest that all women, and most likely men, would benefit from regular fish intake," says Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts University in Boston. "A tuna fish sandwich counts, as does almost any other type of fish that is baked, broiled, grilled, or poached." But she points out that fried fish, which is often cooked in hydrogenated oils, is not helpful.

In research on more than 200 women, performed at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts, scientists found that the arterial blockages among women who dined on fish were less (and impeded blood flow less) than in women who hardly ever ate seafood. Fish was especially helpful for women who had diabetes, a disease that makes you more prone to heart and circulation problems (American Journal of Clinical Nutrition 9/04).

These effects are important: Heart disease is the number one cause of death for women, and older women who suffer from diabetes are particularly susceptible. The number of people with diabetes has been increasing of late, mainly due to the fact that Americans are overweight. Right now about 18 million people have diabetes and another 20 million are expected to suffer this condition in the next four decades.

" This study shows that following the current guidelines of eating at least two servings of any type of fish per week slows down the progression of heart disease in women with coronary artery disease (CAD), especially those who were also diabetic," says Dr. Lichtenstein, coauthor of the study. "We further found that eating one or more servings per week of fish that is rich in omega-3 fatty acids, such as tuna or other dark-fleshed fish, is equally effective."

Dangerous disruptions in heartbeat, known as arrhythmias, may also be affected by fish oil. "[E]xperiments show that fatty acids from omega-3 fish oils are stored in the cell membranes of heart cells and can prevent sudden cardiac death or fatal arrhythmias," notes Alexander Leaf, MD, medical researcher and professor at Harvard University.

Fat for Your Brain

The right kind of fat is also crucial for the function of your nerves and brain tissue, which is 60% to 70% fat. Incorporating omega-3 fatty acids into those cells can help keep your brain firing on all synapses. It may lower your risk of Alzheimer's disease, an irreversible form of mental deterioration that kills 100,000 Americans a year. About a thousand people a day in the US are found to have Alzheimer's, and experts believe that over the next 40 years 14 million of us will be doomed to being enveloped by the mental fog this condition produces.

Research indicates that our brains probably need omega-3 fats for protection against the kind of damage that causes our mental capacities to slip. Once Alzheimer's starts, deterioration accelerates because brain cells start losing these fats.

In experiments performed at the David Geffen School of Medicine at UCLA (Neuron 9/2/04), scientists looked at how a lack of docosahexaenoic acid (DHA, one of the omega-3 fats found in fish), affected the cellular processes that lead to Alzheimer's. They found that the part of brain cells that receive signals from other brain cells, the receptors, are vulnerable to damage from chemical reactions that take place inside the cells. However, DHA offers antioxidant protection against this destruction.

When brain cells were denied DHA, the cells' receptors suffered extra harm. But when fish oil was present, brain cells were protected. In addition, animals that received extra omega-3s were better able to learn and find their way through mazes.

Greg Cole, PhD, senior researcher on this study and a professor of neurology at Geffen, says, "We saw that a diet rich in DHA, or docosahexaenoic acid, dramatically reduces the impact of the Alzheimer's gene [which made the animals more susceptible to Alzheimer's]. Consuming more DHA is something the average person can easily control. Anyone can buy DHA in its purified form, fish-oil capsules, high-fat fish or DHA-supplemented eggs." Fishes rich in omega-3s include salmon, halibut, mackerel, sardines and herring.

Protecting Kids from Asthma

A surprising benefit of omega-3s has been found in pregnant women and their newborns: Pregnant women with asthma who eat fish rich in omega-3s during their pregnancy lower their children's risk of asthma.

Not just any fish will do. The study (American Thoracic Society International Conference 5/25/04) discovered that mothers who ate fish sticks during pregnancy doubled the asthma risk in their kids. " Fish sticks are deep-fried, and they contain omega-6 fatty acids, which encourage inflammation of the airways," says study co-author Frank Gilliland, MD, PhD, professor at the Keck School of Medicine at the University of Southern California. "Oily fish [like salmon and trout] contain omega-3 fatty acids, which appear to be anti-inflammatory, and lead to the reduced potential for developing asthma and allergies."

The USC investigation showed that when women with asthma ate oil-bearing fish during pregnancy, the risk of asthma for their children dropped more than 70%. The more fish that mom consumed, the less likely her baby was to develop asthma. Unfortunately, the study did not find the same benefit in women without asthma.

" A family history of asthma is a very strong risk factor for a child developing asthma," Dr. Gilliland says. "It appears that oily fish interacts with the genes involved in the predisposition to develop asthma, and somehow reduces the risk."

Although most of us try to avoid accumulating unsightly fat around our hips, the right kind of fat plays an integral part in the functioning of our bodies and may even keep us alive. Fats don't get much better than that.

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Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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The Joints Are Jumping

Date: June 11, 2005 04:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Joints Are Jumping

The Joints Are Jumping by Rachel Alexander Energy Times, October 8, 2003

It usually starts with a twinge in your back or an ache in your knees: Knee stiffness, back pain and joint inflammation can signal the beginning of arthritis.

According to the US Food and Drug Administration, arthritis affects over 42 million Americans-that's 1 in every 3 adults-and costs the economy nearly $65 billion annually. But as common as arthritis is, it doesn't have to extract a high cost from your joints.

Who's At Risk?

Arthritis literally means an "inflammation of the joints" and can affect anyone-from small children to 80-year-olds. Some groups are more prone to certain types of arthritis; for instance, those over 40 are at greater risk for developing osteoarthritis, a degenerative condition of the joints.

According to Johns Hopkins Medical Institute, more than 50% of all individuals over the age of 40 have x-ray signs of osteoarthritis in weight-bearing joints (such as those in the knees and hips), and nearly half of those over 65 have measurable symptoms of arthritis. Osteoarthritis is often caused by overuse, age, excess weight or genetics, or by a combination of these factors.

Rheumatoid arthritis, on the other hand, is a disease of the immune system that affects the joints, which can make it harder to diagnose because early symptoms-fatigue, weakness, loss of appetite and low-grade fever-can mimic other chronic conditions.

Stiffness and pain may or may not accompany the initial symptoms of rheumatoid arthritis. However, joints eventually become inflamed and swollen. Although less common that osteoarthritis, rheumatoid arthritis affects more than 2 million Americans.

Covering Up the Signs

Treating arthritis can involve the use of both conventional and non-conventional therapies.

"In osteoarthritis specifically, conventional medicine has just been focused on covering up the symptoms," says Jason Theodosakis, MD, author of The Arthritis Cure (St. Martin's Press). "In the history of medicine, this approach has been considered primitive."

But Dr. Theodosakis points out that treatment often depends on the type of arthritis involved: "Rheumatoid arthritis patients should be taking prescription drugs that are known to prevent the disease from progressing. [Use] alternative medicine as an adjunct..."

Conventional therapies often involve the use of non-steroidal anti-inflammatory (NSAID) medicines, such as ibuprofen and naproxen. The chief drawback of NSAIDs is the toll these treatments extort from the gastrointestinal system.

In fact, a 2002 study conducted by researchers at the University of South Florida, Tampa, found that more than 15% of patients developed digestive problems after a five-week course of ibuprofen. In addition, ibuprofen may increase blood pressure.

Newer prescription NSAIDs called COX-2 inhibitors, which work by suppressing the body's inflammatory response, also carry risks of side effects ranging from diarrhea and fluid retention to liver damage and kidney problems. In addition, people with asthma or chronic allergies (including to aspirin) should not take these medicines.

Corticosteroids-another treatment option that has been used to lessen inflammation-can cause side effects such as increased appetite, mood changes and even immune system breakdown.

Natural Answers

A growing body of evidence shows that nutrients such as glucosamine and MSM, coupled with lifestyle changes, can help decrease or eliminate some of the aches and pains of arthritis. Glucosamine is a natural chemical that helps build joints. When the cartilage in joints deteriorates due to age or other factors, studies indicate that glucosamine provides the necessary building blocks for rebuilding and repairing this tissue.

In one investigation (Archives of Internal Medicine 2002; 162:2113-23), scientists discovered that glucosamine slowed the progression of osteoarthritis and improved symptoms for over 200 patients. Another study, conducted by researchers in the Netherlands, demonstrated that a combination of glucosamine and chondroitin holds promise for conditions such as spinal disc degeneration.

To date, several studies have confirmed glucosamine's ability to help the symptoms of arthritis, and the National Institutes of Health is currently supporting research to further study the benefits of glucosamine.

Other Joint Aids

MSM is often an adjunct therapy as it does not work directly on joints, but provides the raw materials, in this case sulfur, to help rebuild cartilage in the joint matrix. Studies indicate that sulfur has a protective effect and may interact with magnesium, an essential bone nutrient.

Traditionally, the herb horsetail (Equisetum arvense) has been used to supply silica, a mineral component of nails, bones and joints. Its support of these structures can help in the fight against arthritis.

As the body ages, it may lose much of its silica reserves. Resupplying much of this mineral may help support joints. In addition, experts believe, silica can help the body use calcium more effectively and support bone health.

Since rheumatoid arthritis is a systemic affliction, you should work with a trained health professional in treating it. Complementary care practitioners often use antioxidant nutrients, such as vitamins C and E, to reduce free radical damage, along with pantothenic acid (vitamin B5) to lessen morning stiffness.

A Joint Project

According to Dr. Theodosakis, exercise is the key to dealing with arthritis: "[Start with] an individualized exercise program that strengthens the joints without causing more damage...and an eating program to control your weight if you are currently overweight." To limit the effects of arthritis, you should quit smoking, since smoking generates free radicals that can harm the tissues which make up joints. In addition, a strict vegan diet may help alleviate some of the pains of rheumatoid arthritis.

Dr. Theodosakis also recommends looking for hidden causes of symptoms, such as food allergies, that may contribute to arthritis.

Heat helps ease arthritis pain and encourages both blood flow and tissue repair. A plain, old-fashioned hot water bottle works quite well. Or you can use one of the newer heat-generating wraps, which are thin enough to be worn under clothing and don't have to be constantly reheated.

You can't always avoid arthritis, especially as you get older. But you don't have to let it get the better of you.

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Vitanet ®

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Breast Cancer

Date: June 10, 2005 09:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Breast Cancer

Breast Cancer by Joseph L. Mayo,MD Mary Ann Mayo, MA Energy Times, May 2, 1999

What do you fear most? Bankruptcy? Floods? Heart disease? If you're like many women, breast cancer stands near the top of that dreaded list.

But that fear doesn't permeate other cultures the way it does ours.

A woman like Mariko Mori, for instance, 52 years old, Japanese, worries about intense pressures beginning to burden her toddler grandson. But worry about breast cancer? Hardly.

In Indiana, Mary Lou Marks, 50, has similar family frets, mulling over her 28-year-old daughter's career choice.

But on top of that, when Mary Lou tabulates her other worries, she recoils at the thought of breast cancer. She's heard about her lifetime risk: 1 in 8. Meanwhile, Mariko's is merely 1 in 40, according to Bob Arnot's Breast Cancer Prevention Diet (Little, Brown).

American Problem
Experts reporting in "Women at High Risk for Breast Cancer: A Primary Care Perspective" (Prim Care Update Ob/Gyns, vol. 5, no. 6, 1998, p. 269) say the risk of developing breast cancer for the average American woman during ages 40 to 59 is 3.9%; by 60 to 79 years of age that rises to 6.9%. A high-risk 40-year-old has a 20% chance of breast cancer in the next 20 years.

New studies have found the effect of carrying the gene linked to breast cancer, which is responsible for only 5 to 10% of breast cancer incidence, is not as great as first suspected. Earlier estimates that the gene reflects an 80% chance of incurring breast cancer by age 70 has been recalculated to be only 37% (The Lancet, 1998;352:1337-1339).

Complex Causesbr> Researchers agree: No one factor is solely responsible for breast cancer. Risk depends on many factors, including diet, weight, smoking, alcohol consumption, activity level and, of course, those genes.

Regardless of their actual chance of getting breast cancer, women worry. Mary Lou faces no factors that would place her in particular jeopardy. But her anxieties about radical therapies and medical expenses paralyze her: She forgets to visit her health care provider and skips her annual mammogram appointments. Mary Lou's daughter, perhaps in reaction to her mother's gripping fears, campaigns ardently for cancer prevention, educating herself and mobilizing against the cumulative effects of known cancer risks. Smart young woman: A malignancy, after all, can take years to develop. A tumor must swell to one billion cells before it is detectable by a mammogram.

Dietary Benefits
Of all the tactics for reducing the risk of breast cancer, diet ranks high on the list.

The soy-rich regimen of Japanese women like Mariko Mori, for example, helps to explain the low breast cancer rates in Asian countries (see box at center of the page).

Tomatoes, because of their high quotient of the carotenoid lycopene, have been found to protect cells from the corrosive clutches of oxidants that have been linked with cancer in 57 out of 72 studies (The Santa Rosa Press Democrat, February 17, 1999, page A6, reporting on a Harvard Medical School study). For more on tomatoes see page 16.

But there's no one magic anti-cancer food or diet. Eating to prevent breast cancer requires a balanced menu with fiber, healthy fats, phytoestrogens and antioxidants, all fresh and free of chemical additives.

Modifying the balance and type of estrogen, the female sex hormone produced by the ovaries, offers an important breast cancer safeguard. Fat cells, adrenal glands and, before menopause, the ovaries, produce three "flavors" of estrogen, the strongest of which, estradiol, is believed to be carcinogenic when too plentiful or persistent in the body.

Estrogen does its work by attaching to estrogen receptors. Receptors are particularly numerous in the epithelial cells that line milk sacs and ducts in the breasts.

A receptor site is like a designated parking spot: Once estrogen is parked there it triggers one of its 400 functions in the body, from preparation of the uterus for pregnancy to intensifying nerve synapses in the brain.

The food we eat can be a source of estrogen; plant estrogens, called phytoestrogens, are much weaker than the body's estrogens, but they fit the same receptors. Phytoestrogens exert a milder estrogenic effect than bodily estrogen and are capable of blocking the more potent, damaging versions.

Finding Phytoestrogens
Foods high in phytoestrogens include vegetables, soy, flaxseed and herbs such as black cohosh, chasteberry, red clover and turmeric. Soy is the darling of the day for good reason. Both soy and flaxseed can lengthen periods, reducing the body's overall exposure to estrogen.

Soy also contains genistein, an "isoflavone" very similar in molecular form to estrogen but only 1/100,000 as potent. Because of its structure, genistein can attach to cells just as estrogen does; it also helps build carriers needed for binding estrogen and removing it from the body (Journal of Nutrition 125, no.3 [1995]:757S-770S). It acts as an antioxidant to counteract free radicals.

Tumor Inhibition
Studies have demonstrated that genistein inhibits angiogenesis (new tumor growth), slowing the progression of existing cancer.

Soy is most protective for younger women. Postmenopausal women benefit from soy's ability to diminish hot flashes and for cardiovascular protection, especially in combination with vitamin E, fiber and carotene (Contemporary OB/GYN, September 1998, p57-58).

Experts don't know that much about the cumulative effect of combining hormone replacement with soy, herbs and a diet high in phytoestrogens. Menopausal women who boost their estrogen this way should work with their health care providers and monitor their hormonal levels every six to 12 months with salivary testing.

The Vegetable Cart
Some vegetables are particularly protective against breast cancer because they change the way the body processes estrogen. Indol-3-carbinol, found in the co-called cruciferous vegetables such as cauliflower, broccoli and cabbage, diminishes the potency of estrogen. (Broccoli also contains isothiocyanates that trigger anti-carcinogenic enzymes.) These vegetables supply fiber, beta-carotene, vitamin C as well as other vitamins and minerals (Proc of the National Academy of Science USA, 89:2399-2403, 1992).

Fiber from fruits, vegetables and whole grains reduces insulin levels and suppresses the appetite by making make us feel full, thus helping with weight control, so important to resisting cancer. Fiber also helps build estrogen carriers that keep unbound estrogen from being recirculated and reattached to the breast receptors.

Cellulose, the fruit and vegetable fiber most binding with estrogen, also rounds up free radicals that damage DNA within cells.,p> Feeding the Immune System Despite heightened public awareness and efforts to stick to wholesome, healthful diets, experts increasingly link poor nutrition to depressed immune systems. Many Americans are at least marginally deficient in trace elements and vitamins despite their best attempts to eat well; that's why a good multivitamin/mineral is wise, even mandatory. Vitamins given to people undergoing cancer treatment stimulate greater response, fewer side effects, and increased survival (International Journal of Integrative Medicine, vol. 1, no. 1, January/February 1999).

Nutrients tend to work synergistically on the immune system. They should be taken in balanced proportions, and in consultation with your health care provider.

Immune Boosters
In Research links low levels of calcium and vitamin D, an inhibitor of cell division and growth, to higher breast cancer rates.

n Riboflavin (B2), pyridoxine (B6), pantothenic acid (B5), zinc and folate strengthen immunity. Selenium, in lab culture and animal studies, has helped kill tumors and protect normal tissues.

n Beta-carotene and vitamins A, E and C are antioxidants. Vitamin C enhances vitamin E's effects, boosting immunity and protecting against cell damage. The antioxidant isoflavones in green tea, with soy, convey the anticancer effects of the Asian diet. Research shows actions that discourage tumors and gene mutations.

The food you eat influences hormones. Excess sugar raises insulin, which acts as a growth factor for cancer and interferes with vitamin C's stimulation of white blood cells. It may contribute to obesity.

Alcohol is converted to acetaldehyde, which causes cancer in laboratory animals. It affects gene regulation by decreasing the body's ability to use folic acid. It increases estrogen and the amount of free estradiol in the blood. The liver damage that accompanies high alcohol consumption frequently reduces its capacity to filter carcinogenic products, regulate hormones and break down estrogen. Studies of alcohol consumption have caused experts to estimate that drinking more than two alcoholic beverages a day increases breast cancer risk by 63% (OB-GYN News, November 1, 1998, p. 12).

Fat Can be Phat
Fat conveys nutritional benefits. Not all fats are bad: we can't survive for very long without certain fats. Fat can turn you into a "well-oiled" machine. But the wrong kind of fat (the fatty acids in red meats and fatty poultry) is believed to be a major culprit in breast cancer.

Fat cells produce estrogen. Excess fat stores carcinogens and limits carriers that can move estrogen out of your system.

Once estrogen has attached itself to a receptor, the health result depends on the type of fat in the breast. Saturated fat, transfatty acids and omega-6 fat from polyunsaturated vegetable oils such as safflower oil, peanut, soybean oil, corn oil and in margarine can increase the estrogen effect and trigger a powerful signal to the breast cell to replicate.

Restraining Prostaglandins
Blood rich in the essential fatty acids omega-3 and omega-9 lowers cancer risk by driving down levels of prostaglandins, which promote tumor growth. The blood and tumors of women with breast cancer usually contain high levels of prostaglandins.

Breast tissue is protected by omega-3 fat chiefly from fish and flaxseed and by omega-9 from olive oil. Salmon once a week or water packed tuna three times a week are particularly beneficial. Fish oil supplements processed to reduce contaminates are available. Cod liver oil isn't recommended: its vitamin A and D levels are too high.

Flaxseed is the richest known plant source of omega-3. Use a coffee grinder to benefit from the seed and oil for the full estrogen effect; sprinkle ground flaxseed over cereal or fold into baked goods. Drizzle flaxseed oil, found in the refrigerator section of your health food store, over salads or cereal. (Store the oil in the refrigerator.)

Olive oil, especially in the context of the so-called Mediterranean diet of vegetables, omega-3-rich fish and fresh fruit (Menopause Management, January-February 1999, p. 16-19), lowers the risk of breast cancer (The Lancet, May 18, 1996;347:1351-1356).

Selecting Organic Food
Select organic foods for extra anticancer protection. Pesticides stimulate erratic cell action and often inhibit the estrogen carrier's ability to attach and remove estrogen from the body. Free floating estrogen then can attach to breast receptors and cause trouble.

Buy or grow fresh, organic foods whenever you can. When grilling meat, fish or poultry, reduce the area where carcinogens may accumulate by trimming fat. Charred, well-done meat is known to be carcinogenic. When grilling, marinate meat first and reduce the cooking time on the grill by slightly precooking.

Cancer prevention is an interlocking puzzle requiring the limitation of fat consumption, weight control, exercise, stress reduction and care for psychological and spiritual balance. Possessing more cancer fighting pieces makes you more likely to be able to complete the prevention picture.

Joseph L. Mayo, MD, FACOG and Mary Ann Mayo, MA, are the authors of The Menopause manager: A Safe Path for a Natural Change, an individualized program for managing menopause. The book's advice, in easy-to-understand portions, isolates in-depth explanations with unbiased reviews of conventional and alternative choices. A unique perspective for mid-life women who want to know all their options.

Also from the Mayos - The HOW Health Opportunities For Women quarterly newsletter to help women learn HOW to make informed health choices. Learn HOW to: - Choose nutritional supplements

- Integrate natural remedies with conventional medicine.

- Pick healthier foods.

- Reduce breast cancer, osteoporosis and heart disease risk.

- Slow aging's effects. Protect against environmental toxins.

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Vitanet ®

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Fighting Arthritis Naturally

Date: June 10, 2005 02:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fighting Arthritis Naturally

Fighting Arthritis Naturally

by Donna Lee Nardo Energy Times, January 8, 2002

The annoying pain of arthritis grows ever more annoying: one of every six Americans, 43 million people, suffer arthritis, the leading cause of disability in the US. No pharmaceutical can reliably cure arthritis or slow its progression without possibly causing side effects. But you can help heal your hurting joints with nutrients and other natural substances.

Every move you make hinges on healthy joints. The hinge joints in your fingers, knees and elbows swing back and forth. Ball and socket joints in our hips and shoulders twist and turn our arms and legs. But when arthritis attacks, joint function narrows, causing pain, stiffness, swelling and inflammation. While scientists search for the root cause of arthritis, they recognize that aging, injuries, allergies, a genetic tendency toward arthritis and being overweight all contribute to your risk. Researcher have identified more than 100 types of arthritis, including osteoarthritis (OA), rheumatoid arthritis (RA), gout, lupus, scleroderma, vasculitis, myositis, infectious arthritis, degenerative joint disease and spondylitis. OA and RA represent two of the most common arthritis forms. OA generally attacks the finger joints and larger joints like the hips and knees. Cartilage lining the joint deteriorates, often as a by-product of aging, but this deterioration can happen at any age. Sprains, fractures and repetitive injuries can increase your chances of osteoarthritis. Rheumatoid arthritis occurs when joints become inflamed and your immune system apparently releases antibodies in response to allergens. This type of arthritis can destroy and immobilize joints. Traditionally, doctors have treated arthritis with acetaminophen, aspirin and other drugs called non-steroidal anti-inflammatory drugs (NSAIDs). However, NSAIDs often offer only short-term relief. They can cause bleeding problems and ulcers. And while they may slow inflammation and pain, they also do nothing to repair damaged joints. A 1995 Journal of Rheumatology article also warned that prolonged NSAID use actually furthers deterioration of the joints (Oct/95; 22 (10):1941-6).

Glucosamine at Work

Scientists believe that injuries and aging deplete the body's supply of glucosamine, a natural substance that forms, maintains and repairs joint cartilage. Glucosamine supplements are thought to replenish the supply and are prescribed for arthritis therapy in many countries. Several studies indicate that glucosamine tackles pain and inflammation as effectively as NSAIDs without the side effects. It also helps rebuild arthritic joints. Research supporting glucosamine's benefits abounds in Europe and Asia. One study suggests that glucosamine sulfate supplements relieve pain as well as the NSAID ibuprofen (Osteoarthritis and Cartilage 1994; 2 (1):61-9). A recent Belgian study testing the effectiveness of glucosamine on patients with OA of the knee captured the attention of the American medical profession. Results suggest that glucosamine promotes physical changes in joints that halt the progression of OA (Lancet 2001, Jan 27; 357 (9252):251-56). After analyzing data from scores of clinical trials, the National Institutes of Health (NIH) saw enough promise in glucosamine to launch its own multi-year study.

Healing Spice

Scientists have been testing the orange-yellow herb turmeric and have found that it may ease arthritis discomfort. Long a staple in the medical practices of Asia, turmeric has anti-inflammatory and antioxidant properties that reduce swelling and pain associated with arthritis. Researchers think this spice, used in such Indian cuisine as curry, may work more effectively than cortisone and other drugs that reduce inflammation. Ellen Kamhi, PhD, RN, and co-author of Arthritis: An Alternative Medicine Definitive Guide, considers turmeric an important therapy for arthritis. "Turmeric is quite effective, and it's much safer than conventional drug anti-inflammatories, with far fewer possible adverse effects," says Dr. Kamhi, clinical instructor at the State University of New York-Stony Brook Medical School. One study on people with RA demonstrated that the natural benefits of turmeric equaled those provided by a popular prescription drug known to cause side effects (Indian J Med Res 1980; 71:632-4). Another trial, published in the Journal of Ethnopharmacology, found that turmeric possesses unique anti-inflammatory properties (1993; 38:113-119). A trial published in 1994 also found that turmeric acts as an antioxidant to help protect joints (J Pharm Pharmacol; 46:1013-16).

Aging Joints

As we age, our bodies require more antioxidants to fight off damage caused by destructive molecules known as free radicals. Researchers believe that antioxidant nutrients can afford arthritis protection. A 10-year study evaluating the effect of vitamins C and E on the joints concluded that both nutrients protect against cartilage deterioration (Arthritis & Rheumatism 1996, April; 39 (4):648-56). According to Dr. Kamhi, "Arthritis is a lifestyle disease (and) no one remedy, either natural or pharmaceutical, will heal or reverse the arthritic process. Organic foods, exercise, stress reduction, and supplements can lead to a marked decrease in all arthritis symptoms with minimal side effects and enhanced overall health and wellness." While arthritis often makes sufferers limit their activity, experts agree that a sedentary lifestyle only exacerbates problem joints and that exercise maintains your range of motion. The type of activity recommended for each particular form of arthritis differs: for osteoarthritis, specific exercises like stretching and moving arthritic joints can help if more strenuous exercise forms are not possible. Rheumatoid sufferers need to use extra caution to prevent inflammatory flare-ups by balancing gentle exercise with rest. In any case, keep moving: performing household chores or spending time on your hobbies will profit painful joints.

Weight Control

In many cases of arthritis, maintaining an appropriate weight is critical. Surplus weight places extra stress on joints and accelerates cartilage deterioration. And don't be discouraged if your mainstream doctor pooh-poohs complementary arthritis control. "Any practitioner who categorically dismisses the use of all-natural therapies," advises Dr. Kamhi, "is not keeping up with reading current medical literature."

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VitaNet ®
VitaNet ® Staff

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The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease

Date: June 09, 2005 05:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease

The Latest Breakthroughs in Garlic Research

on Cancer and Cardiovascular Disease

Presented at the 2005 World Garlic Symposium

Many of the world’s top-level scientists gathered in Washington D.C. this week for the 2005 Garlic Symposium, entitled, “Significance of Garlic and its Constituents in Cancer and Cardiovascular Disease.” The conference provided current scientific information about the effect of garlic and its constituents on health and performance. The symposium was held at the Georgetown University Conference Center on April 9-11, 2005.

“For the first time in seven years authorities in various fields of garlic research from all over the world to provide the latest updates, specifically regarding aged garlic extract and its actions in diseased states including heart disease and cancer,” commented Dr. Matthew Budoff, M.D. cardiovascular researcher at UCLA. “Garlic has been used medicinally for thousands of years in virtually all ancient cultures. Now, new metabolic roles for garlic are being proposed and there are many promising lines of research.”

Presentation highlights included:

• Clinical Intervention Trial and pre-clinical substantiation on Cancer using Garlic, presented by National Cancer Institute scientists, Mitchell Gail and John Milner Mounting evidence points to the anticancer properties of aged garlic extract and a number of specific organosulfur compounds from garlic. These prevention characteristics arise through both a dose and temporal related change in several cellular events including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis and angiogenesis.

• Inhibition of Coronary Arterial Plaque Accumulation by Garlic, presented by Matthew Budoff, Harbor-UCLA Medical Center

Effect of aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study that determined that the atherosclerotic plaque burden detected by electron beam tomography (EBT) changed significantly with the use of aged garlic extract, Patients in Dr. Budoff’s study were able to significantly lower their total cholesterol, blood pressure, homocysteine and LDL cholesterol oxidation levels with aged garlic extract supplementation.

• Influence of Garlic on Endothelial Dysfunction in Hyperhomocysteinemia, presented by Norbert Weiss, University of Munich in Germany Aged Garlic Extract (AGE) minimizes intracellular oxidant stress and stimulates NO generation in endothelial cells. Preliminary results show that pretreatment with AGE for six weeks diminishes the adverse effects of acute high homocysteine on endothelium-dependent brachial artery vasodilatation and on acetylcholine-induced stimulation of skin perfusion.

• Anti-glycation properties of aged garlic extract: possible role in prevention of diabetic complications, presented by Nessar Ahmed, Manchester Metropolitan University in England Aged garlic extract inhibited the formation of advanced glycation end products, which have been previously shown to increase the risk of diabetic complications ranging from heart disease to retinopathy, kidney failure, impaired wound healing and many more.

“Garlic is turning out to be a major player in cancer and heart disease prevention and control, especially in combination with drug treatments,” said Richard Rivlin, M.D. of Strang Cancer Prevention Center at Cornell. “It’s also showing us that we can start early. It’s madness to treat cancer and heart disease in their advanced stages. We need to start early and aged garlic extract is an excellent way to do that.”

Almost 400 scientific studies have been completed on aged garlic extract, done in major universities worldwide. These studies have focused on a variety of heart disease risk factors such as cholesterol, high blood pressure, homocysteine levels, inhibiting LDL oxidation, anti-platelet aggregation and adhesion, stimulating blood circulation; in addition to other studies on immune stimulation, cognitive effects, liver function and anti-tumor effects. .

Abstracts

PRECLINICAL PERSPECTIVE ON GARLIC AND CANCER. John A. Milner, National Cancer Institute, Rockville, MD 20892

Mounting evidence points to the anticancer properties of fresh garlic extracts, aged garlic, garlic oil, and a number of specific organosulfur compounds from garlic. These prevention characteristics arise through both a dose and temporal related change in several cellular events including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis and angiogenesis. A block in carcinogen activation through modulation of cytochrome P450-dependent monooxygenases and/or acceleration of carcinogen detoxification via induction of phase II enzymes likely account for some of this protection. The block in preneoplastic lesions and/or tumors in several sites suggests a generalizable mechanism. The efficacy of water- and lipid-soluble allyl sulfur compounds against chemical carcinogenesis appears comparable, although more studies are needed. A shift in sulfhydryl groups, redox status or enzyme catalysis may account for some of the phenotypic changes. They may also account for the observed hyperphosphorylation of specific cell cycle related proteins and histone hyperacetylation; both of which have been correlated with suppressed tumor cell proliferation. Several forms of allyl sulfur compounds are effective in blocking cell division and inducing apoptosis, but notable differences in the efficacy among these various compounds and across tumor types are evident. While the expression of many genes and proteins can be influenced by allyl sulfides; the challenge is to determine which is responsible for a phenotypic change. Additional studies are needed with more modest exposures and over prolonged periods and that utilize transgenic and knockout models to assist in the identification of molecular targets. Finally, additional research is needed to identify sensitive “effect” and “susceptibility” biomarkers that can ultimately be used to identify responders from non-responders.

INHIBITION OF CORONARY ARTERIAL PLAQUE ACCUMULATION BY GARLIC. Matthew Budoff, Harbor-UCLA Medical Center, UCLA School of Medicine, California, USA

Effect of Aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study to determine whether the atherosclerotic plaque burden detected by electron beam tomography (EBT) will change at a different rate under the influence of AGE or placebo. EBT can non-invasively quantitate the amount of coronary calcification and track atherosclerotic plaque over time. Nineteen of 23 patients completed the study protocol. The patients were well matched for age, gender, statin use and cardiac risk factors. Patients underwent EBT and blood testing at baseline, and then again after 12 months of randomization. The average change in the calcium score (Volumetric method) ± SD for the AGE group (n = 9) was 7.5 ± 9.4% over the one year. The placebo group (n = 10) demonstrated 22.2 ± 18.5% annual progression, significantly greater than the treated cohort (p = 0.01). While there were no significant changes in cholesterol parameters, or C Reactive protein between the groups, high density lipoproteins and plasma homocysteine in the AGE group demonstrated a trend toward improvement compared to the placebo patients. Thus, although this is a small-scale trial, it demonstrates the potential of AGE to inhibit the rate of atherosclerosis (progression of coronary calcium), as compared to placebo over one year. Larger studies need to be performed to assess this potential anti-atherosclerotic therapy and the impact on coronary events.

INFLUENCE OF GARLIC ON ENDOTHELIAL DYSFUNCTION IN HYPERHOMOCYSTEINEMIA. N. Weiss, N. Ide, T. Abahji, L. Nill, C. Keller, U. Hoffmann. Klinikum der Universität München, D-80336 Munich, Germany

Endothelial dysfunction (ED) due to decreased bioavailable nitric oxide (NO) by increased vascular oxidant stress plays a critical role in the vascular pathobiology of hyperhomocysteinemia (hhcy). Aged Garlic Extract (AGE) minimizes intracellular oxidant stress and stimulates NO generation in endothelial cells. We performed a placebo-controlled, blinded, cross-over study to examine whether AGE prevents macro- and microvascular ED during acute hhcy induced by an oral methionine challenge in healthy subjects. Acute hhcy leads to a significant decrease in flow-mediated vasodilation of the brachial artery as determined by vascular ultrasound, indicative of macrovascular ED, as well as a decreased number of recruited nailfold capillaries during postischemic reactive hyperemia as determined by videomicroscopy, and to a decreased ratio of acetylcholine (endothelium-dependent) vs. sodium nitroprusside (endothelium-independent) iontophoresis induced skin perfusion as measured by laser doppler flowmetry, indicative of microvascular ED. Preliminary results show that pretreatment with AGE for six weeks diminishes the adverse effects of acute hhcy on endothelium-dependent brachial artery vasodilation and on acetylcholine-induced stimulation of skin perfusion. Whether or not this is accompanied by changes in biochemical parameters of ED is still under investigation. It is concluded that AGE may at least partly prevent a decrease in bioavailable NO during acute hhcy.

Bibliographies

David Heber, MD, PhD, FACP, FACN

Professor, UCLA Department of Medicine - Division of Clinical Nutrition, at the David Geffen School of Medicine, UCLA, and UCLA School of Public Health; Director, UCLA Center for Human Nutrition; Director, NIH Center for Dietary Supplement Research in Botanicals (CDSRB); Director, NCI-funded Clinical Nutrition Research Unit; Vice Chair, UCLA Collaborative Centers for Integrative Medicine; Member, UCLA's Jonsson Comprehensive Cancer Center

Matthew Budoff, MD, FACC

Matthew Budoff, MD, FACC, is an associate professor of medicine at the UCLA School of Medicine and program director for the Division of Cardiology, as well as director of the Electron Beam CT Laboratory at Harbor-UCLA Medical Center in Torrance, Calif. He completed his undergraduate work at University of California, Riverside, and earned his medical degree at George Washington University in Washington D.C. Dr. Budoff’s efforts to identify and modify risk factors for cardiovascular disease using electron beam CT have been extensively published. His latest research focuses on the progression of arteriosclerosis.

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GlucosaMend™ Tissue/Joint Repair Complex

Date: June 02, 2005 11:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GlucosaMend™ Tissue/Joint Repair Complex

GlucosaMend

More than 40 million Americans experience joint discomfort. But exciting new research proves you can do something about it. Our health and well-being is inextricably linked to lifestyle choices: the right combination of exercise, weight training and supplementation can strengthen muscles and joint tissues to minimize stress and degradation. Targeted nutrition to the multiple body systems related to joint and connective tissue can help maintain flexibility and joint comfort. GLUCOSAMEND supports the musculoskeletal system with structural building blocks and tissue production cofactors, as well as aiding the body’s mechanisms for soothing relief and antioxidant defense.

Bio-Aligned Formula™ GLUCOSAMEND is uniquely effective because it is a Bio-Aligned Formula. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance.

Musculoskeletal System—Structural Building Blocks

Certain building blocks of joints and connective tissue can help maintain joint integrity and comfort. Glucosamine is a major constituent of glycosaminoglycans, which in turn form proteoglycans, molecules that hold and bind the water that lubricates joints, disperses stress and nourishes joint tissue. The amino acids proline and lysine are structural components of collagen and elastin, which give strength to connective tissue. GLUCOSAMEND contains glucosamine sulfate, N-acetyl glucosamine, proline and lysine.

Musculoskeletal System—Tissue Production Cofactors

Some micronutrients are necessary as cofactors in the production of connective tissue. For example, vitamin C and copper help form hydroxyproline and hydroxylysine, main constituents of collagen. A unique property of grape seed extract is its ability to form a bond between broken collagen fibers, helping to repair them and restore flexibility and strength to connective tissues and joints. GLUCOSAMEND provides vitamin C, zinc, manganese, copper, and grape seed extract to address these cofactors.

Soothing Relief Mechanisms

Some herbs and nutrients have the capacity to support the body’s natural mechanisms for increasing comfort. Boswellia, for example, is an herb with soothing properties, while vitamin B-6 helps to stabilize collagen and elastin. Additional herbs and nutrients, acting in conjunction with antioxidant protectors, support tissue comfort and health. GLUCOSAMEND contains Boswellia serrata, quercetin, copper, and vitamin B-6.

Antioxidant Defense

The health and integrity of joints and tissues—specifically of cell membranes— is supported by botanicals and nutrients that support the body’s natural antioxidant response. When tissues become damaged, the body mounts a repair process that ultimately generates free radicals. These free radicals can also break down healthy cells and tissues in the process, hence the need for antioxidants to neutralize and break the cycle. GLUCOSAMEND provides grape seed extract, vitamin C, zinc, selenium, copper, quercetin to neutralize free radicals.

Lifestyle Tips for Healthy Joints: A Strategy for WellnessSM

Healthy lifestyle habits should be part of your individual strategy for joint wellness. Source Naturals believes in a holistic approach to living. Not only can supplements bring balances to your individual body systems but certain lifestyle choices can also bio-align your health. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, limit saturated fat and eliminate hydrogenated oils. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAME, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CHONDROITIN to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage.

Structural Building Blocks N-Acetyl Glucosamine, Glucosamine Sulfate, L-Lysine, L-Proline Tissue Production Cofactors Grape Seed, Copper, Manganese, Zinc, Vitamins A, B-6 and C, Niacinamide Soothing Relief Mechanisms Boswellia Serrata, Quercetin, Turmeric, Copper, Magnesium, Zinc, Vitamin C Antioxidant Defense Grape Seed, Quercetin, Manganese, Selenium, Zinc, Vitamins A, C and E

References
Bhavan’s, B. H. Selected Medicinal Plants of India (A Monograph of Identity, Safety, and Clinical Usage) Bombay: Chemexcil, 1992. Dore-Duffy, P., et al. (1990, Nov-Dec.). “Zinc profiles...” Clinical and Experimental Rheumatology 8.6: 541-46. Ellis, J. M. (1985, Winter). “Vitamin B6 deficiency and rheumatism.” Anabolism. Lakshmi, R., et al. (1991, Oct-Dec.). “Effect of riboflavin or pyridoxine deficiency on inflammatory response.” Indian Journal of Biochemistry and Biophysics 28.5-6: 481-84. Leibovitz, B., (1991). Nutrition Update 5.3: 5. Levine, M. (1986). “New concepts in the biology and biochemistry of ascorbic acid.” New England Journal of Medicine 314: 892-902. Pavelka, K, Gatterova, J., Olejarova, M, Machacek, S., Giacovelli, G., Rovati, L.C., (2002). “Glucosamine Sulfate Use and Delay of progression of Knee Osteoarthritis: A 3-Year, Randomized, Placebo-Controlled, Double-Blind Study. Arch Intern Med, 2002 October 14; 162(18):2113-23. Roubenoff, R., et al. (1995, Jan.). “Abnormal vitamin B6 status...” Arthritis and Rheumatism 38.1: 105-9. Shampe, P., and R. Harvey. Lippincotts Illustrated Reviews: Biochemistry. Philadelphia: J. B. Lippincott Company, 1987. Tarp, U., et al. (1985). Scandanavian Journal of Rheumatology 14.2: 97-101. Volpi, N., (2002). “Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers,” 2002 Oct; 10(10):768.

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Date: May 09, 2005 06:10 PM
Author: Darrell Miller (dm@vitanetonline.com)

It's in the Blood

Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

“The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

“Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

"Blur of Products"

With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

“The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

“Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

“The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

“In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

New Weapons

There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

“Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

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