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How Does Nattokinase Help Improve Cardiovascular Health?

old message How Does Nattokinase Help Improve Cardiovascular Health Darrell Miller 04/29/11


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Date: April 29, 2011 04:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Nattokinase Help Improve Cardiovascular Health

Nattokinase And Your Health

Nattokinase is an organic compound that occurs naturally in the Japanese food natto, or fermented soybeans. It is an enzyme that acts on fibrous proteins responsible for blood clothing, and as such has been commercially touted to work like thrombolytic medications to a certain degree. Its synthesis involves fermentation that results from adding the bacterium Bacillus subtilis to boiled soybeans.

Natto is a traditional dish in Japan. It has enjoyed long-standing popularity among the Japanese people since feudal times largely owing to its reinvigorating effects on the blood. In recent years, laboratory studies point to the presence of chemical compounds in fermented soybeans. The enzyme nattokinase appears to be the active ingredient, improving fibrinolytic activities in animal subjects.

Breaks Down Blood Proteins

Proteases are enzymes capable of reducing proteins into smaller peptide chains in the digestive system or anywhere in the body. A special kind of protease called plasmin is found in the blood. It is the primary enzyme that facilitates the catabolism of fibrin clot, or coagulated blood protein. Fibrinolysis is the process initiated by the enzyme plasmin to dissolve compacted red blood cells.

Thrombolytic drugs work on the principle of raising the levels of plasmin in the blood. Streptokinase is one of these drugs. It is commonly administered in the treatment of myocardial infarction, or heart attack to avoid complications. Natto has been compared to streptokinase, and oral intake of nattokinase has been observed to stimulate productions of plasmin.

Prevents Blood Coagulation

Nattokinase has been extensively studied in Japan, though well designed large-scale randomized clinical trials are still needed to establish its purported benefits to human health. There is buzz around nattokinase in the pharmaceutical industry especially as early studies suggested that it may ameliorate complications of cardiovascular diseases, notably in the removal of platelet-fibrin emboli.

There have been numerous citations on the blood-thinning capacity of nattokinase. This enzyme is also believed to have an inhibitory effect on platelet aggregation. Thrombocytes, or platelets, are necessary for containing excessive bleeding. However, aggregation of platelets may result in thrombosis in patients with history of atherosclerosis and other disorders of the blood vessels. Nattokinase is a blood thinner that affects both platelets and fibrins.

Improves Cardiovascular Health

In addition to its thrombolytic and anticoagulant properties, nattokinase has been reported to promote normal flow of blood. Natto has been linked to the alleviation of high blood pressure and has seen desirable outcomes in hypertensive patients. Recent studies have shown that nattokinase is responsible for producing antihypertensive and vasodilator effects when natto enters the systemic circulation. It is postulated that nattokinase inhibits angiotensin-induced vasoconstriction.

The Japanese have always believed that natto is good for the blood. Nattokinase remains under scrutiny, but clinical trials are well underway. A growing body of literature devoted on promoting its alleged health benefits draws so much on decades-long anecdotal evidence.

If you want to improve cardiovascular health, give Nattokinase a try!





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Atherosclerosis, Blood Vessels, Cardiovascular, Enzyme,
Fermentation, Fibrin, Japan, Natto,
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