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Researchers identify how inflammation spreads through the brain after injury

old message Researchers identify how inflammation spreads through the brain after injury Darrell Miller 03/09/17


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Date: March 09, 2017 02:59 PM
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Subject: Researchers identify how inflammation spreads through the brain after injury





Researchers have identified a new mechanism by which inflammation can spread throughout the brain after injury. This mechanism may explain the widespread and long-lasting inflammation that occurs after traumatic brain injury, and may play a role in other neurodegenerative diseases. This new understanding has the potential to transform how brain inflammation is understood, and, ultimately, how it is treated.

Key Takeaways:

  • The researchers showed that micro-particles derived from brain inflammatory cells are markedly increased in both the brain and the blood following experimental traumatic brain injury (TBI).
  • Research has found that neuroinflammation often goes on for years after TBI, causing chronic brain damage. The researchers say that the micro-particles may play a key role in this process.
  • The researchers studied mice, and found that in animals who had a traumatic brain injury, levels of micro-particles in the blood were much higher. Because each kind of cell in the body has a distinct fingerprint, the researchers could track exactly where the micro-particles came from.

"This new understanding has the potential to transform how brain inflammation is understood, and, ultimately, how it is treated."



Reference:

https://www.google.com/url?rct=j&sa=t&url=https://www.eurekalert.org/pub_releases/2017-03/uoms-rih030717.php&ct=ga&cd=CAIyGmZmMDFkMTU2YWMzMmQ5OTU6Y29tOmVuOlVT&usg=AFQjCNFO4Bw39e0n9xh_7bF6J7Qo8BXSXA




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