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old message Kudzu - Herbs with alcohol intake suppressive agents ... Darrell Miller 05/25/05

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Date: May 25, 2005 09:25 AM
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Subject: Kudzu - Herbs with alcohol intake suppressive agents ...

Kudzu and the discovery of daidzin and its anti-dipsotropic activity

  • Kudzu has diadzin a substance that has shown to reduce alcohol consumption in all lab test results.

    • Definition:

  • aldehyde dehydrogenase (ALDH), the major enzyme involved in the detoxification of acetaldehyde, the primary and highly reactive metabolic intermediate of ethanol(alcohol) metabolism.

    • D A I D Z I N : A PO T E N T I A L A G E N T FO R T H E T R E A T M E N T O F A L C O H O L DE P E N D E N C E

    A. Anti-Dipsotropic Activity of Daidzin and Crude Extract of RP

    For more than a millennium, extracts containing RP or FP have been used apparently safely and effectively for the treatment of ‘‘alcohol addiction’’ in China.

  • in 1993 proof of anti-dipsotropic effects of daidzin (A substance found in kudzu) -- 12 At a dose of 1.5 g/kg/day, i.p., a crude alcoholic extract of RP reduced hamster ethanol intake by more than 50%

    • Intake of Kudzu may help reduce alcohol consumption in those with abusive consumption of alcohol.



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