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If You Are Having Trouble With Night Driving, Bilberry Extract Could Help Darrell Miller 2/2/11
Hops And Good health Darrell Miller 9/20/09
Isoflavones Darrell Miller 9/2/08
Butcher's Broom Extract Darrell Miller 5/2/08
VITAMIN A and CAROTENOIDS - What are they good for? Darrell Miller 6/9/05



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If You Are Having Trouble With Night Driving, Bilberry Extract Could Help
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Date: February 02, 2011 10:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: If You Are Having Trouble With Night Driving, Bilberry Extract Could Help

Night blindness is very common nowadays. According to statistics, a lack of vitamin A is the primary cause of night blindness or inability to see at night or in dim light. The treatment of this eye condition will depend upon the cause. Treatment may be as simple as getting a new eye glasses prescription. But invasive procedures may also be required most especially those that are caused by cataracts. Fortunately, Bilberry extracts may help night blindness. bilberryleafplant

Bilberry is a low – growing perrenial shrub growing approximately 15 to 20 inches in height. It is a member of the family Ericaceae in the genus Vaccinium. Its branches are green with sharp edges. It bears edible berr that is seemingly wrinkled and black. Bilberry is a comparative to the common berries known as blueberry and cranberry. The active compounds in bilberry fruit are known as anthocyanosides. Bilberry extract has a deep bluish purple tone which contains the majority of the active substance of the fruit known as anthocyanidin. Anthocyanidin is a component of anthocyanosides. It can help increase the formation of rhodopsin. According to studies, rhodopsin is formed from an aldehyde form of vitamin A called retinaldehyde, or retinal as commonly used. It is then bound to the protein opsin. This compound consisting of retinal and opsin is stored in photoreceptors of the retina of the eye known as rods and Cones. Rhodopsin is the compound in the eye that is responsible for adjusting eye perception to light variations.

This plant extract is also commonly used for treating eye problems like cataracts and retinal disorders particularly retinopathy. Scientists found out that anthocyanosides help protect the retina. Since bilberry improves the formation of rhodopsin, adequate levels of rhodopsin can significantly improve night vision and reduce visual fatigue. This eye pigment could help those individuals who are having trouble driving at night because of its rhodopsin regenerating property.

Aside from supporting a healthy eye function, bilberry has many other health benefits. It has an antioxidant, anti – inflammatory, collagen stabilizing and vasoprotective properties. Generally, anthocyanosides are considerably beneficial to the overall health of the body. It can improve circulation by preventing blood clumping by reducing platelet aggregation. It can also prevent or reduce the amount and extent of damage to cells caused by free radicals.

Further clinical studies are being done to be able to get concrete evidence on the fruit’s benefits especially to the eyes. Preliminary results show that bilberry decreases eyestrain after an excessive use of computers, protects against glaucoma by improving blood vessel integrity in the eyes, reduces the occurrence of cataracts by maintaining the integrity of connective tissues in the eyes and lessens the risk of retinopathy among diabetic patients. Preparations of bilberry extracts include teas, capsules or tablets.

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Hops And Good health
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Date: September 20, 2009 08:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hops And Good health

Hops are the female flower Cones, which are also known as strobiles, of the hop plant. The hop plant is part of the Cannabaceae family, which also includes hemp. Primarily, hops are used as a flavoring and stability agent in beer. The first documented use in beer is from the eleventh century. Today, hops are used extensively in brewing because of their many benefits. Among these are balancing the sweetness of the hops with bitterness. However, hops are also used for various purposes in other beverages and herbal medicine.

Nicholas Culpeper, a seventeenth-century herbalist, suggested the use of hops to open obstructions of the liver and spleen, cleanse the blood, loosen the belly, cleanse the veins, and promote urination. Hops were used as food by the Romans. Gerard, a famous herbalist, recommended using the buds in salads. Native American tribes also found hops to be of value. The Mohicans used it as a sedative and also for toothaches, while the Menominee tribes used hops as a cure-all. The lupulin that is found in hops is described as both a sedative and hypnotic drug. It was recognized in the U.S. Pharmacopoeia from 1831 to 1916. Most often, hops are probably used in the production of beer.

Hops are best known for their sedative action. Also, they are used for their antibiotic properties. These properties are beneficial for sore throats, bronchitis, infections, high fevers, delirium, toothaches, earaches, and pain. Although hops are strong, they seem to be safe to use. Their main uses are to alleviate nervous tension and promote a restful sleep. They have been used to naturally relieve insomnia. For inflammation, boils, tumors, and swelling, a poultice of hops is recommended. Hops have been used as a stimulant to the glands and muscles of the stomach. They have also been used as a relaxant on the gastric nerves. Hops have a relaxing influence on the liver and gall duct and a laxative effect on the bowels. Many studies indicate that hops have sedative properties. This herb is known to be fast-acting, soothing, and calming to the nervous system. Hops are often nervine herbs that aid in promoting sleep. Certain elements of the plant have been shown to possess hypnotic effects. Hops are also used for their antispasmodic effects. Additionally, hops contain antibacterial properties, which validates some of their historical uses.

The flower of the hops plant is used to provide alterative, anodyne, antibacterial, antibiotic, antineoplastic, carminative, cholagogue, galactagogue, nervine, sedative, stomachic, and vulnerary properties. The primary nutrients found in this herb are chlorine, copper, fluorine, iodine, iron, lead, magnesium, manganese, sodium, vitamin B-complex, and zinc. Primarily, this herb is extremely beneficial in treating appetite loss, bronchitis, delirium, gastric disorders, headaches, hyperactivity, and indigestion, insomnia, absent lactation, nervousness, pain, and excessive sexual desire.

Additionally, this herb is very helpful in dealing with alcoholism, anxiety, blood impurities, coughs, intestinal cramps, dizziness, earaches, fevers, gas, jaundice, kidney stones, liver disorders, menstrual symptoms, menopausal symptoms, neuralgia, restlessness, rheumatism, skin disorders, sleeplessness, toothache, ulcers, venereal diseases, water retention, whooping cough, and worms. For more information on the many beneficial effects provided by hops, please feel free to contact a representative from your local health food store with questions.

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Isoflavones
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Date: September 02, 2008 10:10 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Isoflavones

An isoflavone from soy has been evaluated for its effect on various female functions such as the menopause and some effects on estrogens. Soy products have been part of the diet in the Far East for thousands of years, and it is a known fact that these people suffer fewer incidences of conditions such as breast cancer, menopausal problems, rectal cancer and diseases of the heart and joints.

The benefits that such a diet appeared to confer on those taking it initiated many studies into the active constituents of soy, and how the biochemistry involved imparted these benefits. A result of this was an intensification of investigations into many so-called -women's functions' or 'women's problems' that hitherto had been accepted as a part of life. Now, however, they are better understood, just as many other components of the Oriental diet are being found to have wider implications in terms of disease prevention and increasing life expectancy. So back to soy and its isoflavone content.

Soy contains a number of isoflavones, commonly known as phyto-estrogens - plant estrogens - because their chemical formula is similar to that of estrogen, a female hormone. Isoflavones possess some properties that support the beneficial properties of estrogens, and others that suppress some of the risk factors possessed by estrogen. We shall discuss here how these isoflavones are related chemically to estrogens, and how they can be used to support some specific female functions.

In order to understand how isoflavones work we go back to the 1980s, when alpha and beta estrogen receptors were discovered. Until then, the biochemistry of estrogen was not fully understood, and problems connected with estrogen had not been fully investigated.

Like all hormones, estrogen works by finding receptors that are located on cells. With regard to estrogen there are two types of receptor. The beta receptors are connected with the beneficial properties of estrogen, while the alpha receptors tend to lead to the unfavorable effects such as cancers related to estrogen. Each of your different tissue types possesses different ratios of these two receptor types.

The unfavorable alpha receptors predominate in tissues such as the breast, ovaries and uterus. The favorable beta receptors predominate in the blood cells, bladder, prostate gland, thymus and bones. Studies have indicated that isoflavones appear to attack to the beta receptors and simulate the beneficial effect of estrogen when the levels of estrogen in the body are low, and allow the proper functioning of these cells in the body.

The alpha cells are also populated by isoflavones, which then protect these areas of your body against cancers that can be stimulated by estrogen, such as cancers of the breast, ovaries and uterus. It appears that cancers that can develop when the alpha receptors are populated by estrogen do not occur when isoflavones have captured them

Isoflavones are present in the form of glucosides. These are composed of sugar and non-sugar components, the latter known as aglyCones, and the main isoflavones in soybean are based on the three aglyCones genistein, daizein and glycetein. The glucosides are water soluble and are broken down into enzymes known as B-glucosidases in the intestine. This releases the aglyCones that can be further metabolized into other substances.

Current studies are examining the possibility that a diet rich in isoflavones taken early in life up to teenage years can reduce the incidence of breast cancer in later years. Isoflavones have been used in the laboratory to reduce the growth of prostate cancer cells, and animal studies have reinforced this finding. The fact that Japanese men suffer less from prostate cancer than those eating diets low in isoflavones also tend to reinforce this connection.

The same mechanism can be used to in prostate cancer by binding to testosterone receptors. Genistein, in particular, can help treat certain types of cancer by inhibiting enzymes such as tyrosine kinase that can become hyperactive and overstimulate the growth of potentially cancerous cells.

It is probable that the estrogen binding facility of isoflavones complements the activity of estrogen in women with low levels of hormone. When the female estrogen level is low, isoflavones can reduce the effects of the menopause and symptoms such as hot flushes and night sweats become less severe. While not all women benefit, it has been found that women with these symptoms tend to suffer less when taking a diet rich in soy foods containing isoflavones.

In addition to its moderating effect on these cancers, and its effect on the menopausal symptoms on many women, soy isoflavones possess a few other beneficial health properties. They are strong antioxidants, and help to support the immune system by mopping up free radicals. They also help to protect from atherosclerosis by preventing the oxidation of LDL cholesterol and depositing it as plaque in the arteries.

There is evidence that isoflavones in the diet can help to maintain strong healthy bones. This is largely through the fact that Chinese women taking a diet rich in soya suffer fewer fractures than those on a low soy diet, but studies are continuing into potential reasons for this. Estrogen receptors in bones regulate bone growth and density. Isoflavones can modulate these receptors and promote greater bone density just like estrogen hormones with out estrogen side effects.

Isoflavones have few dietary sources, the richest being soybeans and other soy products. These are very low in the non-Asian diet, so few people, other than Asians, receive the benefit of these phytochemicals. This is believed to be the major reason for Asians suffering significantly lower rates of certain cancers than non-Asians.

Soy milk and tofu are the richest sources, although there is no standardization of isoflavones in soy-based foodstuffs. This is because the isoflavone content varies according to growing conditions, although a diet containing the recommended quantities of soy foods, such as soy milk or soy beans, together with a low cholesterol diet, should help women to overcome many of the problems associated with excess estrogen, or a lack of it especially when taking in conjunction with essential fatty acids.

Any supplement containing soy will be beneficial to most women, particularly during the menopausal stages, although the effect of isoflavones on certain cancers to which women are susceptible cannot be ignored. Such supplements should therefore be used by all women from at the teens onwards, studies having indicating that an isoflavone-rich diet should be beneficial over the longer term.

Isoflavones from soy is effective in helping to support female functions, although the normal Western diet is traditionally very short in these forms of phytoestrogen. Isoflavones can modulate estrogen receptor sites through out the body helping the body regulate its functions and easy the symptoms related to a estrogen deficient body.

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Butcher's Broom Extract
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Date: May 02, 2008 11:04 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Butcher's Broom Extract

Butcher’s broom (Ruscus aculeatus) is a member of the lily family, and looks a bit like a holly bush with barbed evergreen leaves and bright red berries in the fall. At one time they were collected, tied together and sold to butchers as brooms to sweep out their shops.

The stiff leaves were particularly suitable for cleaning out offal and other waste products from butchered animals and also for scrubbing butcher’s blocks. It was also used as a deterrent to rodents with their eyes on the meat! Alternative names are sweet broom, kneeholy and Jew’s myrtle, so named because it was used during the Feast of the Tabernacles as one of the ‘four species’ used in the lulav.

The herb was commonly used in Ancient Greece and Rome, the Greeks using it to reduce swellings of various kinds and the Romans using it to treat varicose veins. It has the same uses today, only the mechanisms are understood better. It has been used for centuries in the Mediterranean area for the treatment of inflammations and problems with the circulation, and the Romans used to mash up the leaves and berries to add to wine, and they also used the roots and rhizome as a medicine by soaking them in wine. Today, it is illegal to use holly as a decoration in Italy, so butcher’s broom is used instead.

All parts of the plant are used, including the rhizome, and although it is used as a diuretic, and to control a loss of blood pressure experience by some people on standing up, it is its effect on blood vessels where its main medical benefits lie. Butcher’s Broom can strengthen certain portions of blood vessels, and change the flexibility properties of the cell walls.

The result of this is that the vessels are tightened up, which helps to maintain the flow of blood throughout the body, but also renders the cell walls less likely to leak or crack under stress. The result is a reduction in blood leakage from stretched and weakened blood vessels such as those that result in hemorrhoids, and also of conditions caused by weakened valves in the veins such as varicose veins and spider veins.

The blood pressure in the veins is very weak since they are so far away from the heart, the blood having passed through the arteries, through the capillaries and into the veins on its way back to the heart before being pumped to the lungs. When the valves become weakened, particularly in the large veins in the leg, there is little to prevent the blood from coming under the influence of gravity and pooling back down the vein, causing distention and occasional ruptures.

A ruptured varicose vein can be very serious and cause significant blood loss. Weakened valves can also lead to the formation of blood clots, which is itself a very serious condition that eventually blocks the heart or causes a stroke. Not only can butcher’s broom strengthen the vein walls and prevent leakage, and also enable them to more easily resist the pressure that can cause them to rupture, but it can also be used to break down blood clots. In fact the herb is used in many European hospitals to prevent the formation of blood clots after surgery.

The active ingredients in the rhizome are saponins that contain the aglyCones ruscogenin and neuroscogenin and the associated spirostanol and furostanol glycosides. The receptors that cause vasocontraction are known as adrenoreceptors, these receptors can be selectively stimulated by butcher’s broom extract to tighten the veins and improve the return of blood. When introduced intravenously, butcher’s broom was noted to constrict venules (small veins that feed the main veins but not arterioles (the small arteries than feed the capillaries). Hence blood vessels can be selectively treated, and the effect on isolated blood vessels was enhanced by heating. Many supplements include calcium that helps to strengthen the blood vessel walls.

It is possible, therefore, to target the blood vessels that require constrictive treatment in order that they are strong enough to return blood to the heart rather than leak or distend. However, that is not the only health benefit that butcher’s broom provides. It can also be used as a diuretic. It is not a strong diuretic, but is used to relief the swelling of bruises and PMS, the reason given being that since leakage from the blood vessels is lessened, then more fluid is available to pass through the kidneys. There might be other reasons.

It is also use for the treatment of ortho static hypotension, the reduction in blood pressure that some people experience. It is believed that butcher’s broom can control this condition without increasing blood pressure, as most other remedies do, and which is almost as undesirable as the condition they are treating.

There are few problems associated with the herb, although few studies have been carried out its use by pregnant women. Although the one test that was carried indicated no effect, it would be wise for pregnant or nursing women not to use it until further studies have been carried out. Due to its effect in tightening blood vessels, its use is not recommended by anybody suffering from high blood pressure (hypertension). Many hypertension treatments are designed to render the blood vessels more elastic rather than constrict them.

In one very small study of pregnant women who used a topical cream containing butcher's broom, no side effects were seen for either the mother or the baby. However, very little information is available on how oral butcher's broom might affect a developing fetus, an infant, or a small child. Therefore, its use is not recommended during pregnancy, while breast-feeding, or during early childhood.

Because it tightens blood vessels, butcher's broom may worsen high blood pressure or benign prostate hyperplasia (BPH). Individuals with either of these conditions should not use any form of butcher's broom without first consulting a doctor. The known side effects have already been stated, and they are fairly mild, but few studies have been made on the herb other than in Europe, and the side effects have not been fully explored. It is unlikely; however, that there are any as yet unknown serious side effects since butcher’s broom has been used now for a long time, particularly in Europe.

The term ‘ruscogenin’ is used for the collective mixture of active saponins in butcher’s broom, and many of the supplements are formulated to include from 5 to 15 mg of these. However, check the label, since standardization is not yet required in the USA, and in theory a preparation can include much more or much less ruscogenin. It is frequently supplied with other active ingredients, such as vitamin C or calcium, and perhaps even horse chestnut that affect blood vessels in a similar way. Always follow the instructions on the package, since these are designed for the specific strength of supplement you are using.

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VITAMIN A and CAROTENOIDS - What are they good for?
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Date: June 09, 2005 09:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: VITAMIN A and CAROTENOIDS - What are they good for?

Vitamins

In 1912, Casimir Funk coined the term 'vitamine' to refer to a 'vital factor' he proposed was an essential component present in foods. His conjecture dovetailed with other research, leading to the isolation in the 1930's and 40's of the compounds we now call vitamins.

Vitamins are chemical substances which play a variety of roles in the human body. They are core components of any nutritional supplementation program.

While many people are aware of vitamins as necessary substances for good nutrition, few have a grasp of the extraordinary complexity of the roles they play in our bodies. As you'll see below, vitamins are involved in trillions of biochemical interactions every minute to keep us alive and functioning. For example, B-vitamins are converted into coenzymes which are directly necessary for the production of ATP energy from food, a process that goes on continuously in every cell in the body and which in turn fuels myriad physiological events such as muscle contraction, brain activity or tissue repair.

Source Naturals offers a full line of vitamins in bioactive forms, allowing you to tailor a nutritional supplementation plan to your individual needs.

VITAMIN A and CAROTENOIDS

Vitamin A

Vitamin A is a generic term for a class of fat-soluble substances called retinoids, which can either be consumed preformed or synthesized by the liver from plant pigments called carotenoids (see 'Carotenoids', below). An essential nutrient, vitamin A is perhaps best known for its role in vision.

The outer segments of the rods, a type of light-sensitive cell in the retina of the eye, contain a pigment called rhodopsin (or 'visual purple') that mediates vision in dim light. Cone cells mediate color vision via three additional pigments. Both rods and Cones are surrounded by pigmented epithelial cells that store vitamin A. Rhodopsin is formed from a protein called opsin and a vitamin A-dependent compound called 11-cis retinal. As light strikes the rods and Cones it is absorbed by the pigment molecules, and retinal is split off from opsin. This chemical change allows an electrical impulse to be sent to the optic nerve and thus to the brain. The pigment must then be regenerated from opsin and retinal. Repeated small losses of retinal during this process require a constant replenishment of vitamin A to the eyes.

Vitamin A also plays an extremely important role in epithelial cell differentiation. Cell differentiation is the process by which a cell undergoes a change to a specialized cell type, allowing it to perform particular functions in the body. It is not yet understood precisely how vitamin A is involved in this process. One hypothesis is that it directly affects gene expression through its interaction with chromatin, a complex of DNA, RNA and protein in the cell nucleus. These interactions affect the process of transcription of DNA to messenger RNA, leading to synthesis of a specific group of cellular proteins.

Each one of us carries in our DNA a unique genetic blueprint. This genetic material is the same in every cell of our bodies. It is only because of this mysterious and magical process of differentiation that we have specialized cell types - and therefore eyes, ears, lungs and hearts.

Vitamin A is necessary, either directly or indirectly, for the healthy growth and functioning of many of our tissues and organ systems, including the eyes, the skin, the bones, the reproductive system, and the natural defenses. It is not yet known whether this requirement is due to the role of vitamin A in cell differentiation or whether there are other physiological processes for which vitamin A is essential.

Carotenoids

Vitamin A is related to a class of nutrients called carotenoids, including alpha and beta carotene, lycopene and lutein. Carotenoids are botanical pigments whose colors range from red to orange to yellow. Some carotenoids, particularly beta carotene, can be converted into vitamin A predominantly in the intestinal mucosa and to some extent in the liver. Carotenoids are completely non-toxic; their conversion into vitamin A is well-regulated by the body, making them extremely safe sources of this essential nutrient.

In addition to their role as safe sources of vitamin A, carotenoids are powerful nutrients in their own right. Their primary claim to fame is their powerful antioxidant action, particularly against singlet oxygen. Singlet oxygen is an 'excited' ion of oxygen which, while not technically a free radical, is nonetheless highly reactive. It causes 'oxidative' reactions which can impair or destroy membranes, enzymes and DNA. It can also lead to the formation of free radicals which can cause additional damage.

Certain carotenoids such as beta carotene, because of their chemical structure, can neutralize singlet oxygen by absorbing its extra energy and dissipating it throughout the carotenoid molecule, releasing the energy as heat and converting the singlet oxygen back to 'normal' oxygen. One molecule of beta carotene can quench up to 1000 molecules of singlet oxygen.

In addition to their role as singlet oxygen quenchers, carotenes provide antioxidant protection against free radicals as well. In nature, they protect plants from photo-oxidative reactions; in humans, certain carotenoids, notably beta carotene, may help protect the skin from such reactions. Other carotenoids may provide more localized protection to particular organs. Lutein and zeaxanthin, for example, are selectively concentrated in the retina of the eye. Along with vitamins C and E, carotenes are among the most important nutrient antioxidants in the human body.



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