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	Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?	Darrell Miller	12/7/23
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	Safe and Effective Joint Pain Relief: Natural Supplements That Work	Darrell Miller	7/21/22
	Can the Liver Be Repaired Once It Is Damaged?	Darrell Miller	4/29/22
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Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were Divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592)

Date: August 02, 2022 05:39 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamins C and D: The Immune System Supplements You Need

It's that time of year again. The leaves are changing color, the days are getting shorter, and people are starting to get sick. If you're looking for a way to boost your immune system, you may want to consider taking vitamins C and D. These two essential nutrients have been shown to be beneficial for immune health, and can help keep you healthy during the cold and flu season. Lets discuss the benefits of Vitamins C and D for immunity, as well as how to get them into your diet.

What are Vitamins C and D, and what do they do for the immune system?

vitamins C and D are essential nutrients that play a vital role in supporting the immune system. Vitamin C is a powerful antioxidant that helps to protect cells from damage, while vitamin D helps to regulate the body's response to infection. Both vitamins are found in a variety of foods, including citrus fruits, leafy greens, eggs, and fatty fish. In addition, both vitamins can also be taken as supplements. While both vitamins are important for immune system health, vitamin C is particularly critical during times of heightened stress or illness, as it helps to boost the body's production of white blood cells. Vitamin D, on the other hand, is essential for maintaining a healthy balance of inflammation in the body. Without adequate levels of vitamin D, the body may become excessively reactive to foreign invaders, leading to chronic inflammation and a higher risk of infection. Together, vitamins C and D play an important role in keeping the immune system functioning properly.

Are there any side effects associated with taking too much of these vitamins?

Although you can get vitamins C and D through your diet, sometimes it's not enough to boost your immune system. The only way to ensure you're getting enough of these essential vitamins is to supplement your diet with pills or injections. Vitamin C is found in citrus fruits, tomatoes, potatoes, and leafy green vegetables. However, your body can't store vitamin C, so you need to consume it on a daily basis. Vitamin D is found in fatty fish, egg yolks, and fortified milk. However, most people don't get enough vitamin D from their diet and need to supplement it with pills or injections. Supplementing your diet with vitamins C and D is the only way to ensure you're getting enough of these essential nutrients to boost your immune system.

How can you make sure that you're getting the most out of your vitamins C and D supplements for immune health?

When it comes to vitamins C and D, there are a few things you can do to make sure you're getting the most out of them. First, vitamin C should be taken in Divided doses throughout the day. This ensures that your body has a constant supply of the vitamin and can make use of it more efficiently. Second, vitamin D can be taken once per day. Finally, remember to take your vitamins with food. This ensures that your body gets the full benefits of the nutrients and doesn't waste any of them. By following these simple tips, you can help ensure that you're getting the most out of your vitamins C and D.

What are some other ways to boost your immune system during the cold and flu season?

While there are many products on the market that claim to boost your immune system, there is no magic pill that can protect you from colds and flu. However, there are a few simple steps you can take to reduce your chances of getting sick. First, make sure you're getting enough sleep. Sleep helps your body to repair and regenerate cells, which is essential for maintaining a strong immune system. Second, eat a healthy diet. Eating plenty of fruits and vegetables will give your body the nutrients it needs to fight off infection. Finally, try to reduce stress. Stress can weaken your immune system, so it's important to find ways to relax and de-stress. Taking these simple steps will help you stay healthy during cold and flu season.

It's important to get enough vitamins C and D to boost your immune system. You can do this by supplementing your diet with pills, eating a healthy diet, and getting enough sleep. By following these simple tips, you can help ensure that you're getting the most out of your vitamins C and D supplements and keep your immune system functioning properly during cold and flu season.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6423)

Date: July 21, 2022 10:41 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Safe and Effective Joint Pain Relief: Natural Supplements That Work

Do you suffer from joint pain? If so, you're not alone. In fact, according to the Arthritis Foundation, over 50 million adults in the United States are affected by some form of arthritis. And if that's not bad enough, it's estimated that by 2030, that number will grow to 67 million! The good news is that there are safe and effective ways to relieve joint pain without resorting to over-the-counter drugs. We'll discuss natural supplements like glucosamine, chondroitin sulfate, and MSM that have been shown to help rebuild cartilage and reduce inflammation.

What is joint pain and what are the most common causes?

joint pain is a common symptom that can be caused by a variety of conditions. The most common causes include arthritis, bursitis, and tendinitis. Arthritis is a general term used to describe inflammation of the joints. There are many different types of arthritis, but the most common are osteoarthritis and rheumatoid arthritis. Bursitis is the inflammation of the small sacs of fluid that cushion the joint, while tendinitis is the inflammation of the tendons that attach muscle to bone. Joint pain can also be caused by injuries, such as sprains and fractures. In some cases, the exact cause of joint pain cannot be determined. Treatment for joint pain depends on the underlying cause.

How can over-the-counter drugs be harmful to your health?

The wide availability of over-the-counter (OTC) drugs such as acetaminophen and ibuprofen can be a godsend when we are feeling pain or discomfort. However, it is important to remember that these drugs are potent medications that can also be harmful to our health if we take them inappropriately. Acetaminophen and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by reducing inflammation, but they can also have adverse effects on the gastrointestinal tract, kidneys, and liver. In addition, NSAIDs can interact with other medications that we may be taking, so it is important to speak to a healthcare professional before taking them. Although OTC drugs can be helpful when used as directed, it is important to be aware of the potential risks involved in taking them.

What are some natural supplements that have been shown to help relieve joint pain safely and effectively?

While there are a number of different supplements that have been traditionally used to help relieve joint pain, not all of them have been proven to be effective. However, there are a few natural supplements that have been shown to be safe and effective for this purpose. Glucosamine is a supplement that has been shown to help rebuild cartilage and relieve pain in osteoarthritis sufferers. Another promising supplement is chondroitin and msm, which helps to reduce inflammation and ease the symptoms of joint pain. Finally, fish oil supplements have also been shown to be effective in reducing inflammation and relieving joint pain. Turmeric, Boswellia, and CBD also reduce inflammation. When used together, these natural supplements can provide significant relief from joint pain.

How do glucosamine, chondroitin sulfate, and MSM work to reduce inflammation and rebuild cartilage tissue?

Glucosamine, chondroitin sulfate, and MSM are all natural compounds that have been shown to be effective in reducing inflammation and rebuilding cartilage tissue. Glucosamine is an amino sugar that is produced naturally by the body. It is a building block of cartilage, and it has been shown to stimulate the production of new cartilage. Chondroitin sulfate is a complex carbohydrate that is also found naturally in the body. It helps to keep cartilage healthy by protecting it from wear and tear. MSM (methylsulfonylmethane) is a sulfur-containing compound that is found naturally in some foods. It has anti-inflammatory properties and has been shown to promote the repair of damaged cartilage. Together, these three compounds can help to reduce inflammation and improve the health of cartilage tissue.

How long should you take these supplements for maximum benefit, and when should you stop taking them if you don't experience results within a certain time frame?

Many people take supplements in order to improve their health or address a specific health concern. But how long should you take them for? In general, most supplements should be taken for at least 6 to 8 weeks in order to see maximum benefit. However, some people may not see results until 12 weeks of supplementation. Of course, if you're working with a healthcare professional, they can help you determine when to start and stop taking supplements. But in general, 6 to 8 weeks is a good rule of thumb. Don't be afraid to add Turmeric or Boswellia to the mix. These herbs can enhance the effectiveness of the glucosamine, chondroitin, and MSM.

Taking a natural supplement like glucosamine, chondroitin sulfate, and MSM can be an effective way to reduce inflammation and rebuild cartilage tissue safely and effectively. These supplements have been shown to be safe and effective for this purpose. When taken together, they can provide significant relief from joint pain. It is important to speak to a healthcare professional before taking these supplements if you are taking other medications, as there is potential for adverse effects. Be sure to take 1500mg of each in Divided dosages though out each day for at least 6 to 8 weeks in order to see maximum benefit.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6419)

Date: April 29, 2022 11:33 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Can the Liver Be Repaired Once It Is Damaged?

https://vitamins.vitanetonline.com/wp-content/uploads/liver-2934612_1920.png The liver is a vital organ in the body that performs many essential functions. It can be damaged by a variety of factors, including disease, alcohol abuse, and exposure to toxic chemicals. Once the liver is damaged, can it be repaired? In this article, we will explore the answer to that question. We will also discuss the various ways that the liver can be damaged and how those damages can be repaired.

What is the liver and what does it do?

The liver is a large, multi-functional organ that plays a vital role in the body. Its primary function is to filter the blood and remove toxins, but it also helps to regulate metabolism, store nutrients, and produce bile. The liver is Divided into two main lobes, the right lobe and the left lobe. The right lobe is slightly larger than the left lobe and includes the quadrate lobe and caudate lobe. The left lobe contains the left lateral section and the medial section. The hepatic veins drain blood from the liver and pass it through the inferior vena cava to be returned to the heart. The hepatic arteries supply oxygenated blood to the liver tissue, while the portal vein carries nutrient-rich blood from the digestive organs. The bile ducts transport bile produced by the liver cells to the gallbladder, where it is stored until needed for digestion.

The liver is a hardworking organ that performs many crucial functions in the body. By keeping it healthy, we can help to ensure that our entire body remains healthy and functioning properly.

What can damage the liver and how does that damage occur?

The liver is a vital organ that performs many important functions, such as filtering toxins from the blood and producing bile to help digest fats. However, the liver can be damaged by a number of different agents, including viruses, alcohol, and certain medications. Viruses such as hepatitis C and hepatitis B can cause inflammation of the liver, which can lead to scarring and eventually to liver failure. Alcohol abuse is also a major cause of liver damage, as it can lead to fatty deposits, inflammation, and scarring. In addition, certain drugs (such as acetaminophen) can cause toxic damage to the liver cells. If the liver is not functioning properly, it can result in a build-up of toxins in the blood, which can lead to serious health problems.

Can the liver be repaired once it is damaged, and if so, how is that done?

The liver is a amazing organ. It is responsible for so many important functions in the body, from filtering toxins to producing bile to breaking down fats. When it is damaged, it can often repair itself. This is because the liver has a high regenerative capacity. hepatocytes, which are the main type of liver cell, can divide and grow back quickly when necessary. In fact, as long as about 25% of the liver remains healthy, it can regenerate itself completely over the course of a few weeks. There are a number of ways to damage the liver, such as through alcohol abuse or viral infections, but fortunately there are also ways to help it repair itself. Eating a healthy diet, getting enough exercise, and avoiding toxins, take liver supporting supplements like milk thistle and NAC can all support liver health and regeneration.

How can people prevent their livers from being damaged in the first place?

The liver is a vital organ that plays an important role in metabolism. However, the liver can also be easily damaged by alcohol, drugs, prescriptions, and environmental toxins, which are in the foods we eat. To help prevent liver damage, it is important to avoid excess alcohol consumption or avoid it all together, take medication as directed and if you are on medications that cause liver damage to discuss alternatives that do not harm the liver, and eat a healthy diet along with taking liver supporting supplements. Additionally, it is important to get regular exercise, as this helps to keep the liver healthy and functioning properly. By taking these steps, people can help to prevent liver damage and keep their organs healthy.

Are there any lifestyle changes or supplements that can help improve liver function even if it has been damaged already?

Liver damage is a serious concern for many people, as it can lead to a number of health problems. While there is no guaranteed way to reverse liver damage, there are some lifestyle changes and supplements that may help improve liver function. One potential change is to limit alcohol consumption, as alcohol is known to be damaging to the liver, mixing alchol and drugs can enhance the progress of liver damage. Additionally, eating a healthy diet and exercising regularly can help improve overall liver function. There are also a number of herbal supplements that are thought to be beneficial for the liver, such as milk thistle and dandelion root. However, it is important to speak with a healthcare provider before starting any new supplement, as some may interact with other medications.

What are the possible consequences of not repairing a damaged liver?

Liver damage can have serious consequences if left untreated. Depending on the cause, there may be a variety of negative effects that result from an injured liver. For example, if the damage is due to excessive alcohol consumption, then scarring and inflammation of the liver tissue can interfere with its ability to filter toxins out of the blood. This can lead to a host of potentially dangerous health problems, including nausea, chronic fatigue, jaundice, and cirrhosis. You must address the cause before change for the good can happen. In addition, unresolved inflammation can increase one's risk of developing more serious conditions such as cancer or heart disease. To prevent these possible consequences, it is important to seek medical attention as soon as possible after suffering from liver damage. This will allow doctors to properly diagnose the issue and develop an appropriate treatment plan. Addressing the cause is always preferable over simply treating symptoms alone. Ultimately, taking action now can help you protect your health in the future.

How can people find out if their livers need repair and where they should go for help if that is the case?

When it comes to liver health, there are a number of ways to find out if your liver needs some repairs. One method is to get tested for elevated liver enzymes, which are indicative of problems with the organ. You can also watch out for certain symptoms, such as fatigue, bloating or skin discoloration. If you notice any of these markers, you may want to consult with your doctor or a specialist in liver disease, who can help determine the best course of action. Depending on the underlying cause of your liver problem, treatment options may include changes to your diet and exercise habits, medications or even surgery in extreme cases. Whatever route you choose, it is essential that you address any issues with your liver as soon as possible in order to protect your overall wellbeing.

Generally, symptoms only show when liver function has dropped significantly.

Liver damage can often go undetected until it has reached a advanced stage. This is because the liver has an incredible capacity for regeneration and can continue to function even when up to 75% of it has been damaged. As a result, symptoms of liver disease often only become apparent when the organ has been severely compromised. By that point, the damage may be irreversible and serious complications may have developed. Therefore, it is important to be aware of the early signs of liver damage so that treatment can be started as soon as possible. These include fatigue, weight loss, abdominal pain, and yellowing of the skin and eyes.

Fortunately, Supplements like Milk thistle and NAC may help the body assist the liver in its repair.

The liver is a hardworking organ that is constantly exposed to toxins. As a result, it is susceptible to damage. Fortunately, supplements like milk thistle and NAC may help the body assist the liver in its repair. Milk thistle contains silymarin, a compound that helps to protect the liver from damage. NAC is an amino acid that helps to remove toxins from the liver. NAC also helps to replenish glutathione, a substance that plays a key role in liver detoxification. Together, these supplements can help to keep the liver healthy and functioning properly.

Whether you are looking for preventative measures to protect the liver or have an existing issue, it can never hurt to take either milk thistle, NAC, or both to support healthy liver function.

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Date: April 27, 2022 11:53 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: N Acetyl Cysteine: A Decades-Old Remedy With Many Uses

Did you know that N Acetyl Cysteine has been around for decades? This powerful supplement was first discovered in the 1950s and has been used as a remedy for many health issues since then. We will discuss the many benefits of N Acetyl Cysteine and how you can start using it to improve your health!

Glutathione and aging

As we age, our natural levels of glutathione tend to decline. This is a major cause of many of the negative effects associated with the aging process, including reduced energy and slower recovery times after illness or injury. Fortunately, there are steps that we can take to increase our levels of glutathione, thus slowing down the aging process and keeping us feeling young and vibrant for longer. Some of these steps include eating a healthy diet rich in antioxidant-rich foods like fruits and vegetables, engaging in regular physical activity to improve circulation, and reducing stress levels through relaxation techniques like yoga and meditation. With these strategies in place, we can help to keep our bodies strong, boost our energy levels, and stay young well into old age. Fortunately, there is a supplement that could help, it is called N Acetyl Cysteine, this substance is a precursor to Glutathione and has been shown to boost glutathione levels.

What is N Acetyl Cysteine and what are its benefits?

N acetyl cysteine has been used as a supplement for many years, and its popularity is likely due to the many benefits it offers. The main function of this compound is to promote the production of glutathione, a powerful antioxidant that protects our bodies from oxidative stress and harmful free radicals. In addition, n acetyl cysteine has been shown to help reduce symptoms of certain mental health disorders, including anxiety and depression. Furthermore, studies have found that n acetyl cysteine may lower blood pressure and improve heart health by increasing blood flow and improving blood vessel function. Overall, it is clear that n acetyl cysteine has been an effective nutrient for many years and continues to be widely used by those looking for an easy way to support their health.

How can you start using N Acetyl Cysteine to improve your health?

N acetyl cysteine (NAC) is a powerful antioxidant that can help to protect cells from damage. It has been shown to be particularly effective in guarding against liver damage, and is often used as a treatment for hepatitis C. NAC can also help to improve lung function and relieve respiratory conditions such as bronchitis and asthma. In addition, NAC has been shown to boost levels of glutathione, which is a key molecule involved in detoxification. As a result, NAC can help to cleanse the body of harmful toxins and pollutants. NAC is available in supplement form, and can be taken orally or intravenously. It is generally well tolerated, with mild side effects such as nausea and vomiting occasionally reported. When taking NAC supplements, it is important to start with a lower dose and increase gradually as tolerated. Those with pre-existing medical conditions should always speak to their doctor before taking any new supplement. Overall, NAC is a safe and effective way to improve your health and protect your cells from damage.

What is the recommended daily dosage for N Acetyl Cysteine per day?

The standard recommended dosage for N-acetyl cysteine (NAC) is 600 mg per day. However, some studies have used dosages as high as 2,400 mg per day. The most common side effect of NAC is nausea, which can be minimized by taking the supplement with food. NAC is also sometimes used as a treatment for chronic bronchitis, and the recommended dosage for this condition is 1,200 mg per day. When used for this purpose, NAC is typically taken in Divided doses of 600 mg twice per day. There is currently no consensus on the optimal dosage of NAC for any particular condition, and further research is needed to determine the ideal dosage for different applications. In acute circumstances, one might need 4000mg to 6000mgs daily in Divided dosages, always work your way up to higher dosages as needed.

What are some of the most common uses for this supplement?

There are many different uses for NAC, or N-acetyl cysteine. This potent antioxidant supplement has been found to be effective in addressing a wide range of health concerns, including asthma and COPD, chronic sinusitis, liver disease, and particularly serious conditions such as cancer. Additionally, NAC has been shown to provide support for the immune system in general and may also serve as a detoxifying agent by helping to eliminate waste products like heavy metals from the body. Overall, there are numerous benefits to using NAC as part of a well-balanced diet. Whether you are looking to improve your respiratory health or strengthen your immune system, this versatile supplement can help you achieve your goals.

NAC composition

NAC, or N-acetyl cysteine, is a complex compound that is composed of various amino acids, including glutamate, glycine, and cysteine. These specific amino acids all play important roles in the function of NAC and affect its many beneficial properties. For example, glutamate increases metabolism and energy levels, while glycine promotes tissue healing and regeneration. Cysteine, on the other hand, facilitates the transport of oxygen and serves as a natural antioxidant. When taken together, these different components work synergistically to promote overall health and wellbeing by supporting key physiological processes such as digestion and immune response. Whether taken as a supplement or consumed through food sources like eggs and milk products, NAC is a versatile substance that is vital to many aspects of our daily health and well-being.

NAC and liver health

N-Acetyl-Cysteine (NAC) is a compound that has numerous benefits for liver health. Studies have shown that NAC can help to protect the liver from damage caused by alcohol and other toxins. It does this by helping to replenish levels of glutathione, a key antioxidant that helps to detoxify the liver. NAC also helps to reduce inflammation and improve blood flow to the liver. As a result, it can be an effective treatment for both acute and chronic Liver diseases. In addition, NAC has been shown to improve the overall health of people with Liver cirrhosis. Consequently, N-Acetyl-Cysteine is a compound that has many benefits for liver health and should be considered as part of any comprehensive treatment plan.

NAC, its sulfur content, and mucus elimination

NAC, or N-acetyl cysteine, is a sulfur-containing amino acid that plays an important role in mucus production and elimination. The sulfur content of NAC helps to thin mucus and make it less sticky, making it easier to clear from the lungs. In addition, NAC helps to break down mucus and remove it from the body. As a result, NAC is often used as a supplement to treat respiratory conditions such as bronchitis and chronic obstructive pulmonary disease (COPD). NAC is typically taken in the form of capsules or tablets, and the recommended dose depends on the individual. However, side effects are rare and generally mild, making NAC a safe and effective option for those seeking to improve their respiratory health.

N Acetyl Cysteine may lower blood pressure

One of these is its ability to lower blood pressure. A review of several studies found that N-acetyl cysteine was effective at reducing blood pressure in people with hypertension. In one study, participants who took N-acetyl cysteine had an average reduction in systolic blood pressure of 9.5 mmHg, compared to those who took a placebo. Other studies have shown similar results, suggesting that N-acetyl cysteine may be an effective treatment for high blood pressure. While more research is needed to confirm these findings, N-acetyl cysteine may offer a safe and natural way to lower blood pressure.

N Acetyl Cysteine may help blood clots - thrombosis

Blood clots are a necessary part of the body's natural healing process. They help to stop bleeding by sealing off damaged blood vessels. However, sometimes blood clots can form in healthy blood vessels, causing a potentially deadly condition called thrombosis. N Acetyl Cysteine is a compound that helps to break up blood clots and prevent thrombosis. It works by preventing the formation of a protein that is essential for clotting. In addition, N Acetyl Cysteine helps to improve the flexibility of blood vessels, making them less likely to rupture. As a result, this compound may help to reduce the risk of thrombosis and improve overall cardiovascular health.

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Date: May 10, 2019 02:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Omega-3s associated with a reduced risk of bleeding in surgery, according to a new study

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Date: May 06, 2019 03:28 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Researchers find that consuming blended protein supplements canimprove energy malnutrition, muscle mass in leukemia patients

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Date: May 06, 2019 03:18 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Omega-3s found to help those suffering from PTSD

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Date: May 02, 2019 02:45 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A species of hawthorn has been found to control abnormally highblood sugar levels

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Date: April 26, 2019 03:15 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Omega-3s found to benefit children diagnosed with behavioraldisorders

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Date: March 27, 2019 03:21 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Eating ginger regularly may suppress the negative effects of ahigh-fat diet

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Date: February 18, 2019 08:50 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Double-blind clinical trial validates cinnamon as natural treatmentfor primary dysmenorrhea

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Date: January 07, 2019 03:36 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Researchers look at the powerful effect of mulberry fruit extracton insulin sensitivity

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Date: December 07, 2018 09:35 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Black cumin oil combined with a low-calorie diet can modulatehormone secretion in obese women

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Date: May 27, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Kudzu Root: Beneficial Herb or Just a Hyped Plant Invader?

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Date: May 12, 2017 06:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Turmeric and diabetes

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Date: April 14, 2017 08:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Clinical tests reveal that black cumin seed (Nigella Sativa) may treat hypothyroidism

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Date: November 18, 2016 07:09 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Medical News Today: What Effect Does Caffeine Have on Depression?

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Date: October 28, 2016 03:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Warning: 4 common vitamins no one told you become toxic if you take too much

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Date: December 23, 2013 02:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Difference between colloidal minerals and ionic minerals.

Minerals are generally Divided into two forms.

Colloids Mineral

Colloids are one form of minerals, where minerals are in stable form. In colloidal form, minerals are evenly distributed in the medium. Minerals in this form will remain in large and organized pattern, and thereby remain in suspension without settling down. These types of minerals are not directly absorbed by the body since they don’t have that electric charge like other minerals. The size of these minerals is also one of the reasons for this. So we can define colloids as, it is a substance, which will not diffuse easily when it is suspended in a liquid medium. Though the colloidal minerals are more dispersed in the body, the absorption is not influenced by that. In order to absorb colloidal minerals, body needs to break down these minerals into smaller units.

Ionic Mineral

On the other hand, ionic minerals can be easily absorbed through the human cell membranes. The main reason for this is, ionic minerals are charged and so the body needs to apply less amount of energy to get them absorbed. The colloidal minerals need to break down into smaller units to attain electric charge and thereby to get absorbed. The electric charge of ionic minerals helps them to travel from a region of higher concentration to a region of lower concentration. Atoms or group of atoms together forms the ionic minerals. They have got charge either positive or negative. During the time of absorption, the body charges the ions and makes absorption easier. Ionic minerals are more easily absorbed by the body than the colloidal minerals, since they have to go through all those process. Even after the different steps of absorption of colloidal minerals, all of them are not utilized by the body. Sodium Chloride and Potassium Chloride are 2 examples for ionic minerals.

References:

1. //www.transformyourhealth.com/webnewsletters/dec06/mineralsvstraceminerals.htm
2. //goaskalice.columbia.edu/whats-difference-between-ionic-and-colloidal-minerals

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Date: December 24, 2012 07:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Benefits of Forskolin

Forskolin is the chemical substance extracted from the root of a plant called coleus forskolin also known as Indian coleus plant. This plant originated in India and its part of mint family. This herb is used to treat various health conditions.

One of the benefits of this herb is its great effectiveness in losing weight. For those people who love looking good, then this product can be of great help. This herb can greatly help wit the reduction of excess fat; this helps in speeding up the process of losing weight.

Forskolin can work in two days.

It works first through stimulating lipolysis and then breaking down the lipids containing fats. This is takes much less time compared to other traditional methods since it raises the cAMP production levels in patients. CAMP regulates glycogen, sugar and lipid. Scientists have proven that this herb can be very beneficial to obese patients. 

Stimulates Thyroid function

Secondly, Forskolin helps in losing weight through is ability to increase the production of thyroid hormone levels. When thyroid production is increased, our metabolism rate increases which leads to weight loss. Typical dosage is 25 to 60mg of forskolin herb per day. This is Divided into 2 or 3 doses. Weight loss can be experienced within a few weeks of regular use of this herb. This herb also helps in lowering blood pressure, therefore preventing blood clots.

An improved blood flow helps maintain a healthy heart. This herb also helps in maintaining healthy lungs. Forskolin is also used in treatment of eczema and psoriasis. It's also beneficial to asthma patients by aiding in relaxing the airways, this helps in respiration process. This product has no known side effects, it can also be taken along with other caffeine's; this provides a boost in the stamina. However, make sure you see your doctor for proper guidance on how to use this product.

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Date: February 09, 2012 05:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Forskoline and How Does It Help You Loose Weight?

While the Ayurvedic Coleus forskohlii contains numerous ingredients, however, the most integral active ingredient in the herb is known as Forskoline. It is the mint family that this herb belongs to, and Burma,India and Thailand, which are all subtropical areas, are some of the places where this herb grows. Over the years, a lot research has been done on the main ingredient in this herb. In the recent times, this ingredient has become particularly popular for the benefits that have been discovered it offers for weight loss.

What Can Forskoline Be Used For?

In the few clinical and scientific studies that were conducted on Forskoline, this natural component was discovered to be a lipolytic or a fat burning agent. The individuals who were subjected to testing lost quite a significant weight when they were give this ingredient to use as a weight loss aid. Ever since then, several weight loss products have been produced that contain this component as their main ingredient.

What is the Function of Forskoline?

The adenylate cyclase enzyme is activated by this component. Typically, adenylate cyclase are also activated by fat burning hormones, however, their have higher CNS effects. On the other hand, the CNS effects of Forskoline are different so no side effects are caused if it is used for losing weight. Thus, while functioning like most fat loss agents, the levels of the lipolytic hormone are not increased by it.

Apart from acting as a safe weight loss agent, Forskoline also offers various other health benefits too. It, in fact, particular helps with cardiovascular health. As far as cardiovascular health is concerned, not only this but several others of the active ingredients that the Coleus forskohlii have been discovered to be beneficial for the cardiovascular system.

What are the Side Effects of Forskoline?

There are actually no known side effects associated with the use of this component, which has been proven by the several studies conducted on it and the herb it comes from. Nonetheless, if people decide to use Forskoline, they should consult a doctor first. There are chances that people might experience drowsiness if they consume in a really large dose, which is natural considering it is an antihistamine, however, this should be avoided. Taking it before going to bed or taking it along with stimulate is most appropriate.

Today there are numerous Forskoline products available in the market and those who are looking for the best one should pay attention to the amount of this particular ingredient the product contains. Typically, a 2% extract in a 250 mg tablet is adequate enough. Products containing 10 to 20% of this extract can be considered the best. People should start using such a product with two to three doses of 25 to 60 mg in a day, Divided accordingly.

These days it is hard to find weight loss products with so many benefits and almost no side effects. The weight loss products containing Forskoline might certainly seem like a miracle for those who want to lose weight and those who decide to use will indeed be able to effectively shed the pounds.

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Date: July 18, 2011 12:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Vitamin B12 Boost Mental Alertness?

The body needs various nutrients in order to make vital biological reactions possible. These bodily reactions are necessary for energy production, immune system enhancement and health improvement. These nutrients are classified into two, macro and micronutrients. In addition, these micronutrients are further Divided into vitamins and minerals. These vitamins are needed by individuals to help the body grow normally. Vitamins can be supplied by the food we eat. However, the body can make certain vitamins such as vitamin D and K. Individuals who are in strict vegetable diet usually need vitamin B12 supplement. In this article, we will be focusing on Vitamin B 12 or also known as cyanocobalamin.

Vitamin B 12 is also a water– soluble vitamin. It is considered as essential because it is not produced by the body. Excellent sources of this vitamin include fish, shellfish, meat, milk and milk products. Vitamin B 12 is also available in supplements in combination with other vitamin B complex. Like the other B vitamins, vitamin B 12 is also necessary in maintaining healthy brain cells and in the normal production of red blood cells. Riboflavin is also a component of DNA which is the cells’ genetic material. Vitamin B 12 in the stomach combines with a substance called intrinsic factor so that it can be absorbed into the blood stream.

Vitamin B 12 boosts mental alertness because it facilitates normal formation of body cells most especially the nerve cells. Vitamin B 12 is also an important component of the myelin sheath. Myelin sheath is necessary for the proper functioning of the nerves. Myelin sheath functions by increasing the speed of the movement of the impulse. With the presence of myelin sheath, the impulse hops from one sheath to another instead of just moving continuously along the nerve fiber. This is the reason why vitamin B 12 is commonly employed for boosting mental alertness and concentration. In fact, it is also commonly employed for treatment of memory loss and Alzheimer’s disease.

Vitamin B 12 can also help lower the risk of cardiovascular diseases by decreasing the concentration of homocysteine in the blood stream. Studies show that high levels of homocysteine can greatly lead to atherosclerosis which is the narrowing of arterial walls. It can also increase the tendency of abnormal blood clotting thus increasing the risk of clotting – related disorders. These factors can precipitate heart attacks and cerebrovascular accidents or commonly known as stroke.

Another function of vitamin B 12 is its involvement with energy metabolism in every cell of the body. Therefore, vitamin B 12 is not only good for enhancing mental alertness but also increasing energy levels. It is also required by the body so that other nutrients from the diet can be absorbed and readily utilized by the cells.

Vitamin B 12 is relatively safe. It usually comes in combination with other B vitamins in the form of tablets, capsules, or liquid which can be bought over –the – counter.

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Date: July 13, 2011 10:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Iodine, The Thyroid, And Radiation! What You Should Know!

What Is Potassium Iodide Good For?

Potassium iodide is also important when there is radiologic exposure or nuclear meltdown since radioactive iodine may be freed into the air thus contamination to human beings and surrounding materials can be highly expected. Exposure may then lead to internal contamination which can be harmful to the body cells most especially with the thyroid gland. The thyroid gland readily absorbs iodine whether in radioactive ionizing or non-ionizing form. If potassium iodide is present, it fills the receptor sites of iodine thus preventing the radioactive form of iodine to be absorbed by the body.

The iodine in the receptor sites is good for 24 hours already. The Food and Drug Administration has approved two preparations of potassium iodide which comes in the form of tablet and liquid. The tablet comes in two dosage, 130 milligrams and 65 milligram. It is also scored so that it can be easily Divided for smaller doses prescribed. The liquid preparation, on the other hand, contains 65 milligram of potassium iodide per one milliliter. Experts suggest that those who are exposed to high doses of radiation can take potassium iodide immediately after a nuclear meltdown or radiation emergency.

Potassium iodide is present among common foods especially sea foods. Kelp which is a large type of seaweeds is very rich in potassium iodide. Studies show that its iodine content is about 90 to 8000 microgram per gram of kelp. To note, the recommended daily allowance of iodine is only 100 to 150 micrograms. FDA recommends specific doses after exposure to large amounts of radioactive iodine. For adults, take 130 milligrams, for breastfeeding women, 130 milligrams is also recommended, for children 3 to 18 years old must take only 65 milligram, however, for children who are 150 pounds or more, 130 milligrams of potassium iodide is suggested. Children who are 1 month of age but less than three years old are recommended to take 32 milligrams or one – half of the 65 milligram tablet. Newborns to 1 month old babies are prescribed to have only 16 mg or one – fourth of the 65 milligram tablet.

The effectiveness of potassium iodide relatively depends on the time interval between the onset of exposure and contamination with radioactive iodine and the time when potassium iodide is taken, therefore, it is highly recommended that potassium iodide is taken just prior or immediately after exposure.

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Date: March 11, 2011 11:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why is It so Important to Give Your Child a Multiple Vitamin Mineral Supplement

Giving a multiple vitamin and mineral supplement to your child is tantamount to protecting him or her from the unknown dangers of malnutrition. It is a fact that children are picky eaters. Besides, not all food that you put on the table provides all the nutrients that they need. Experts remain Divided over the need to give children daily multivitamins, but it is a common belief that doing so is just the prudent choice to make as parents. Does it make any difference? Yes, it does. Research has pointed to the positive effects of vitamin supplementation, and it has been cited a lot of times that the bioavailability of these supplements is not bad at all. This means supplementation does contribute to the well-being of your child.

Ensures to Meet Nutrient Needs

It is not a myth that our diet does not contain all the nutrients that we need. More often than not we are not getting the daily value for all vitamins and minerals as most of us are not able to monitor our eating habits. Also, we don’t have control over how sources of these nutrients change as they undergo the process of heating foods and other cooking preparations. With children being so picky, it is not surprising that they are susceptible to malnutrition. On the other hand, supplementation has been supported by decades-old research to meet the nutrient needs of individuals, including children. If you decide on giving your child multiple vitamin and mineral supplement, do check the label to make sure it says it contains 100 per cent of the recommended dietary intake of all nutrients.

Affects Growth and Development

A number of nutritional supplements available today have been proven to be of utmost help to the reversal of many medical signs and alleviation of diseases. Some of them have been associated with having a positive effect on the chemical reactions within the human body, and multiple vitamins and mineral supplements belong to this category. There is an ever-growing body of literature devoted to the interactions of exogenous compounds within the human body. Research on multivitamins in particular is among the most advanced in pharmacology, with emphasis on how the body effectively digests and absorbs them. Since the availability of vitamins and minerals is important to the physical and mental development of children, modern-day technology focuses on their absorption.

Strengthens Immune Defenses

There is scientific consensus that micronutrients, even trace minerals, boost our immune system. In fact, in individuals who have compromised immune responses, high quantities of vitamins and minerals slow down the progression of opportunistic diseases, as is the case with children with HIV. Children who have strong immune system are known to have levels of micronutrients adequate to ward off common illnesses. The opposite is also true. Multiple vitamin and mineral supplements have long been used to combat the dire effects of malnutrition as deficiencies are almost always reversed with supplementation. That being said, prevention is always better than cure.

Ensure you are getting the daily vitamins and minerals you need to maintain good health with a quality multiple vitamin and mineral.

What is stopping you from taking a multiple today?

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Date: August 25, 2009 12:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Caraway Herb

The caraway plant, also known as Persian cumin, is a biennial plant that is found in the Apiaceae family. This plant is native to Europe and western Asia. The plant is very similar in appearance to a carrot plant, with finely Divided, feathery leaves that have thread-like divisions that grow on twenty to thirty centimeter stems. The main flower stem is forty to sixty centimeters tall and has small white or pink flowers that are in the shape of umbels. The caraway fruits, which are erroneously called seeds, are crescent-shaped and about two millimeters in length and have five pale ridges. The caraway plant prefers warm, sunny locations and a well-drained soil as well.

The fruits of the caraway plant are usually used whole. They have a pungent, anise-like flavor and an aroma that is derived from the essential oils carvone and limonene. These oils are used as a spice in breads, especially rye bread, which is denser due to the yeast killing properties of the essential oil, limonene. Caraway is also used in liquors, casseroles, and other foods, especially in Central European and Northern European cuisine, like sauerkraut. This herb is also used to add flavor to cheeses. A substance made from the seeds is used as a remedy for colic, loss of appetite, digestive disorders, and to dispel worms.

Caraway herbs have been used as a flavoring in foods such as rye bread for thousands of years. It has also been used medicinally by the Romans, Germans, and the English. Generally, it was used to treat flatulence and indigestion. It was also used to relieve colic in babies.

Caraway is very similar to anise. Both of them are recommended for the same purposes. This herb is a powerful antiseptic. It is especially effective in relieving toothaches. When it is applied locally to the skin, it also acts as an anesthetic. This herb can be mixed with other herbs such as mandrake and culver’s root in order to help modify its purgative action. Caraway is also useful in treating stomach problems. Additionally, it helps prevent fermentation in the stomach. It can help to settle stomach after people have taken medication that causes nausea. Caraway also helps to relieve intestinal cramps and colic in babies.

This herb is known to encourage menstruation and the flow of milk in nursing mothers. Caraway also helps to ease uterine cramps.

The root and seed of the caraway plant are used to provide anesthetic, antispasmodic, carminative, diuretic, emmenagogue, expectorant, galactagogue, mild purgative, stimulant, and stomachic properties. The primary nutrients found in this herb are calcium, cobalt, copper, iodine, iron, lead, magnesium, potassium, silicon, vitamin B-complex, and zinc. It is important to consult your local health care professional before taking this, or any supplement in order to obtain the best results. Priamrily, caraway is extremely beneficial in treating loss of appetite, colic, uterine and intestinal cramps, gastric disorders, indigestion, and spasms.

Additionally, this herb is very helpful in dealing with colds, absent lactation, absent menstruation, upset stomach, and toothaches. For more information on the many beneficial effects provided by caraway, feel free to consult a representative from your local health food store with questions.

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Date: August 20, 2009 05:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Anise Herb

Anise is a flowering plant that is part of the Apiaxeae family. It is native to the eastern Mediteranean region and southwest Asia. It is known for its flavor, which resembles licorice, fennel, and tarragon. The anise plant is an herbaceous annual plant that grows to three feet tall. The leaves are at the base of the plant and are very simple. They are about two to five centimeters long and shallowly lobed. The leave higher on the stems are feathery pinnate and Divided into numerous leaves. The flowers of the anise plant are white and about three millimeters in diameter. They are produced in dense umbels. The anise fruit is an oblong dry schizocarp that is about three to five millimeters in length. The seedpods are referred to as aniseed. Anise is usually used as food by the larvae of some Lepidoptera species, such as butterflies and moths. Among these are the lime-speck pug and the wormwood pug.

The best growth for the anise plant can be found in light, fertile, well drained soil. The plants should be started from seeds as soon as the ground warms up in the spring. Because the anise plants have a taproot, they do not transplant well after they are established. For this reason, the plants should be started where they are to grow, or transplanted while the seedlings are still small.

Anise is sweet and very aromatic. It can be distinguished by its licorice-like flavor. It is widely used in a variety of regional and ethnic confectioneries, including British Aniseed balls, Austrailain Humbugs, New Zealand Aniseed wheels, Italian pizzelle, German pfeffernusse and springerle, Netherland Muisjes, Norwegian knots, and Peruvian Picarones. Anise is a key ingredient in Mexican “atole de anis” which is similar to hot chocolate. It is taken as a digestive after meals in India.

Anise was used in ancient Rome as flavoring. However, it contains nutrients like calcium and iron. This herb was added to foods to prevent indigestion when eating large quantities of food. Additionally, it was used to help with bad breath. Hippocrates recommended this herb to relieve both coughs and congestion.

Anise is used to help remove excess mucus from the alimentary canal and the mucus that is associated with coughs. It is used to stimulate the appetite, relieve digestive problems, and treat colic pain. Some herbalists recommend that anise be used for stimulating the glands and vital organs. Among these organs are the heart, liver, lungs, and brain. Additionally, it helps to normalize estrogen levels.

The oil and seeds of the anise plant are used to provide anodyne, anti-inflammatory, antiseptic, antispasmodic, aromatic, carminative, diaphoretic, digestive, diuretic, expectorant, galactagogue, stimulant, and stomachic properties. The primary nutrients found in this herb are B vitamins, calcium, choline, iron, magnesium, and potassium. Primarily, anise provides extraordinary benefits in treating colds, colic, coughs, gas, indigestion, absent lactation, excessive mucus, and pneumonia.

Additionally, this herb is very helpful in dealing with loss of appetite, breath odor, emphysema, epilepsy, nausea, and nervous disorders. It is important to speak with a health care professional before considering supplementing with any nutrient in order to obtain the best results while on medications. For more information on the many beneficial effects provided by anise, please feel free to contact a representative from your local health food store.

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Date: April 03, 2009 02:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamins and Herbs

The whole human body is made up of cells that contain their own genetic material. In a healthy body, these cells divide at a controlled rate, growing and repairing damaged tissues and replacing dying cells. This predetermined rate of cell division is what keeps our bodies healthy. If cells keep multiplying when new ones are not necessary, a mass of tissue, often known as a tumor, is formed. This tumor can be either benign or malignant.

Benign tumors are not cancerous and can occur anywhere in the body. Benign tumors do not cause a threat to health, do not metastasize, and do not grow back if removed. Malignant tumors are cancerous and are usually serious. Often times, they can be life-threatening. Malignant tumors grow uncontrollably, interfere with normal metabolic and organ functioning, and have the ability to metastasize and invade other tissues. If a portion of a cell’s DNA is damaged, the cell can become abnormal. When an abnormal cell divides, it forms new cells that are a photocopy of the damaged genetic material. This ongoing process occurs constantly within our bodies. The majority of the time our bodies have the ability to destroy these abnormal cells and maintain a sort of cellular equilibrium. If a crucial part of the DNA is destroyed and the abnormal cells cannot be controlled any longer, cancer forms. All cancer cells have two things in common: growing uncontrollably and having the ability to metastasize. The immune system does not recognize cancer cells as dangerous or foreign.

Although the exact cause for the cell damage that initiates the cancer process is unknown (theoretically free radical damage causes DNA damage), the chain of events that leads to cancer is very complex, and each individual body reacts differently. It is a combination of genetic, behavioral, environmental, and lifestyle factors that are thought to be involved in turning normal cells into abnormal cells, and abnormal cells into cancer.

There are also factors that are believed to slow the process, while other factors can speed up the process. Possible contributors to the development and growth of cancer can be Divided into three categories: external, internal, and lifestyle. External factors include unhealthy workplace environments and exposure to air and water pollution, chemicals, pesticides, and herbicides. Included in the internal factors include both genetics and infections. Lifestyle factors are those we personally can most readily control, such as diet, smoking, drinking, and sun exposure. External and lifestyle factors account for 80 percent of cancer deaths in the United States.

Just as each of us looks different, each of our bodies has its own unique composition. Some of us may react adversely to what some of us react well to. This is why some treatments prove to be successful for some, but not for others. This is why dietary wellness and prevention is so important. If we can keep our bodies healthy and avoid known cancer-causing agents, we have a good defense against cancer in the first place.

The following nutrients and supplements are designed for persons who have been diagnosed with cancer, as well as for those who wish to enhance their chances of avoiding the disease: coenzyme Q10, colostrum, DMG, garlic, IP6, melatonin, MSM, proteolytic enzymes, selenium, 7-keto DHEA, shark cartilage, SOD, vitamin A, shiitake extract, acidophilus, chromium picolinate, flaxseed oil, grape seed extract, kelp, l-carnitine, multienzyme complex, a multi-mineral complex, multivitamin complex, NAC, raw glandular complex, taurine, and vitamin B complex. Additionally, the following herbs may be beneficial: astragalus, birch, burdock root, cat’s claw, chaparral, chuchuhuasi, cranberry, dandelion, Echinacea, fennel, green tea, licorice root, macela, milk thistle, parsley, pau d’arco, red clover, suma, cardamom, cayenne, ginger, rosemary, sage, thyme, turmeric, ragwort, wood sage, curcumin, essiac, noni, olive leaf extract, rosemary, and boswellia.

All of the above listed herbs and vitamins can help restore the body to good nutrition and help boost the immune system so the body can find and fight back against cancer. Natural vitamins and herbs are available at your local or internet health food store. When purchasing supplements, look for name brand vitamins like Solaray and Source Naturals to ensure you receive quality and you get what you pay for.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Date: January 29, 2009 03:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hoodia

Some companies are already manufacturing a blend of cheaper ingredients with hoodia, and claiming it is better than hoodia alone. This means that you might find a product that contains 1,000 mg of total ingredients, but it could contain as little as 50 mg of hoodia. As a general rule, the other ingredients are only included to make the product cheaper. All hoodia supplies are the same strength worldwide. The stems of the plant are picked, dried, and milled, leaving a powder about 5 percent of the original weight, which is why some quote it as a 20:1 extract. However, don’t be misled. Despite what a label may lead you to believe, you’re only getting 50 mg of hoodia.

The minimum dosage that is necessary to have a usable effect is about 800 to 1,200 mg of actual hoodia each day. This amount will help to reduce your appetite so that you can eat smaller meals and, consequently, lose weight. If you think you’d like to try hoodia, look for a product that has been naturally extracted and grown or ethically wild crafted without the use of chemical fertilizers, pesticides, or preservatives, preferably in a vegetarian capsule.

Make sure that the product you use is a true standardized full-spectrum herbal supplement that does not include any fillers, binders, or common allergens. Also, keep in mind that even though safety reports to date are encouraging, no long-term safety studies have been performed. Additionally, there is no data on the possible interactions hoodia may have with other drugs.

Hoodia is a non-stimulating herb, which makes it more suitable for a large range of people. Herbal stimulants such as guarana or kola nut, which both contain caffeine, can cause a large range of side effects such elevated heart rate and blood pressure, nervousness, and sleeplessness. P57, the active ingredient in hoodia, has no sedative effects.

Losing weight and maintaining an ideal weight also requires changing attitude and lifestyle. If your main goal is to quickly lose weight so you can fit into your bathing suit, you may be able to achieve that lighter weight, but without exercise, you’re still going to look flabby. Even though the subjects in the hoodia clinical study did not exercise, you should, as exercise plays an important role in losing and managing weight along with overall health.

Weight loss should be about your overall health. Without the proper eating habits, especially nutrition and exercise, you won’t be able to accomplish much. It’s true that less weight puts less stress on your cardiovascular system, but you need to exercise to strengthen your heart muscles. Proper nutrition and exercise also helps to prevent many other health problems, which includes fighting off many digestive ailments.

If you’re considering trying hoodia for weight loss, experts suggest that you supplement with 800 to 1,200 mg a day, Divided into two doses and taken with water. For best results, follow the manufacturer’s dosage instructions since products may vary. You should also follow a reduced-calorie diet of natural, unprocessed foods. Even though you can probably lose weight on a diet like this without supplementing with hoodia, adding hoodia may help you to stick to your diet better.

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Date: September 26, 2008 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lutein 20mg (FloraGlo)

Maintains Healthy Visual Function*

It has been well established that lutein is present in high concentrations in the retinal tissue of the human eye. However, a study was conducted in human volunteers to determine whether taking lutein in supplement form actually increased the density of the carotenoid pigments present in the macula. In this study of eight individuals, researchers estimated the density of the macular pigments prior to having each individual take 10 mg of lutein daily in supplement form for 12 weeks. Plasma lutein concentrations were measured at 4-week intervals. During the first four weeks of the study, plasma levels increased five-fold from pre-supplement measures, and then remained at this level for the duration of the study. It was also shown that, due to increased deposition of lutein in optical tissues, macular pigment density increased by an average of 5.3% at the 4-week mark, and continued to increase until the duration of the study.1

A study was also conducted to investigate the possible role of specific nutrients in protecting the lens of the eye against aging, a risk factor for compromised visual function. The study was comprised of 376 individuals aged from 18 to 75. Of the nutrients measured, it was found that the lenses of individuals with higher concentrations of lutein and zeaxanthin showed less of an effect from the aging process. The investigators concluded that these carotenoids might play a protective role in supporting the maintenance of healthy vision.2

The Age-Related Eye Disease Study (AREDS) was a landmark study of the effects of diet and antioxidant supplementation on eye health. The study enrolled over 3500 subjects aged 55 to 80 years who were followed for approximately 6 years. Among the data collected in this multi-faceted study was a self-administered Food Frequency Questionnaire (FFQ). The AREDS Report No. 22 examined the data from the FFQs and determined that, of the nutrients evaluated, only lutein and zeaxanthin were directly related to maintaining eye health with statistical significance3. These findings corroborated similar results of an earlier multi-center study published in the Journal of the American Medical Association that also found that those with a higher intake of lutein and zeaxanthin maintained healthier eye function.4 These promising results have spurred the design of a second major clinical trial (AREDS2), which is currently enrolling participants to study the impact of supplemental xanthophylls (FloraGLO® Lutein and zeaxanthin) and other nutrients on age-related eye health.5

In addition, a double-blind placebo controlled trial was performed in ninety individuals who had signs of compromised visual function. Individuals were Divided into three groups and received either 10 mg FloraGLO® lutein, 10 mg FloraGLO® lutein plus a multivitamin/multimineral formulation, or placebo for 12 months. In both the FloraGLO® lutein and FloraGLO® lutein plus other nutrients groups, improvements were seen in mean eye macular pigment optical density, visual acuity and contrast sensitivity. No improvements were noted in the placebo group.6 These results demonstrate FloraGLO® lutein’s beneficial effect on maintaining healthy visual function.

Newly published research has demonstrated that lutein and zeaxanthin supplementation may enhance visual performance under glare conditions. Forty healthy subjects took daily doses of 10 mg FloraGLO® Lutein plus 2 mg zeaxanthin for six months. They were evaluated for changes in macular pigment, glare disability and photostress recovery at the onset of the study, and at 1, 2, 4 and six months. After six months, subjects experienced an average increase in macular pigment optical density (MPOD) of 39% compared to baseline, and all but two participants experienced some increase in MPOD. This increase in MPOD was also directly related to measured improvements in visual performance after exposure to bright light, as well as photostress recovery.7 This study suggests another way in which lutein and zeaxanthin can help support optimal visual function in healthy individuals.

Potent Antioxidant Protection*

Most of the beneficial effects of lutein are ascribed to its potent free radical scavenging abilities. It is well-known that lutein is a carotenoid related to beta-carotene and possesses antioxidant activity against a number of reactive oxygen species.8

More direct evidence for the free radical scavenging activity of lutein is found in studies of its effects on human lens epithelial cells. Cell cultures were exposed to ultraviolet light after pretreatment with lutein or alpha-tocopherol. Both nutrients were found to reduce ultraviolet-induced damage to lens epithelial cells. However, lutein was shown to have significantly higher photoprotective activity than alpha-tocopherol9 demonstrating its potential as a high-powered antioxidant.

A further review of the mechanisms of lutein in conferring a protective role reveals evidence for its antioxidant activity in various body tissues. Lutein has been shown to be an effective antioxidant in vitro as well as in experimental models of a number of body systems.10

Supports Healthy Skin*

A recent randomized, double blind, placebo-controlled study has demonstrated the positive effects of oral and topical administration of lutein on skin health parameters (surface lipids, hydration, photoprotective activity, skin elasticity and skin lipid peroxidation). Forty female subjects were Divided into four treatment groups. Treatment options included oral administration of 5 mg of FloraGLO® Lutein twice daily or placebo and topical administration of 50 ppm FloraGLO® Lutein twice daily or placebo. Each treatment group received either an active oral treatment with a placebo topical treatment, a placebo oral treatment with an active topical treatment, both active treatments, or both placebo treatments. Statistically significant improvements were seen in all five parameters tested in all treatment groups compared to the group receiving only placebos. The greatest overall improvements were seen in the group receiving both active oral and topical treatments, while lesser but still significant improvement was seen in both the active oral only and the active topical only groups. Additionally, oral administration of lutein conferred superior photoprotective activity (as measured by skin surface redness after exposure to ultraviolet light) and prevention of lipid peroxidation (as indicated by levels of malondialdehyde in skin lipids after exposure to ultraviolet light) than either topical lutein or placebo.11

Diverse Cinical Benefits*

Evidence from various experimental trials suggests that lutein may play a protective role on the circulatory and cardiovascular systems. Its antioxidant activity may also extend to the heart, skin, lungs and blood vessels, making it a nutrient with diverse clinical benefits. Lutein possesses the ability to promote the health of many body tissues.12

Suggested Adult Use: One softgel daily with food, or as directed by a health care professional.

Does Not Contain: milk, egg, wheat, sugar, sweeteners, starch, salt, or preservatives.

Scientific References

1. Berendschot TT, et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Opthalmol Vis Sci. 2000 Oct; 41(11): 3322-6.

2. Berendschot TT, et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Arch Opthalmol. 2002 Dec; 120(12): 1732-7.

3. Age-Related Eye Disease Study Research Group. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol. 2007 Sep; 125(9): 1225-32.

4. Seddon JM, et al. Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration. JAMA. 1994 Nov; 272(18):1413-1420.

5. www.nei.nih.gov/neitrials/viewStudyWeb.aspx?id=120. Clinical Studies Database. Age-Related Eye Disease Study 2 (AREDS2). Last Updated 2/28/2008. Viewed 5/15/2008.

6. Richer S, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr; 75(4): 216-230.

7. Stringham JM and Hammond BR. Macular pigment and visual performance under glare conditions. Optom Vis Sci. 2008 Feb; 85(2):82-8.

8. “Lutein and Zeaxanthin”. PDR Health. www.gettingwell.com/drug_info/nmdrugprofiles/nutsupdrugs/lut_0164.shtml

9. Chitchumroonchokchai C, et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. J Nutr. 2004 Dec; 134(12): 3225-32.

10. Krinsky NI. Possible biologic mechanisms for a protective role of xanthophylls. J Nutr. 2002; 132: 540S-542S.

11. Palombo P, et al. Beneficial Long-Term Effects of Combined Oral/Topical Antioxidant Treatment with the Carotenoids Lutein and Zeaxanthin on Human Skin: A Double-Blind, Placebo-Controlled Study. Skin Pharmacol Physiol. 2007; 20: 199-210.

12. Mares-Perlman JA, et al. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002; 132: 518S-524S.

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Date: July 07, 2007 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Active Coenzyme Q10

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Date: May 11, 2007 10:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Breast Cancer and Natural Supplements

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Date: May 08, 2007 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Memory And Focus

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Date: March 28, 2007 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Regulating Blood Pressure Naturally

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Date: February 25, 2007 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Neurological Health and CoQ10

Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.

Q. Isn’t CoQ10 a supplement for heart health?

A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.

Q. How does CoQ10 affect brain health?

A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.

The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.

The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.

Q. What is the blood-brain barrier and why is it important?

A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.

Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.

Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.

Q. If CoQ10 is made in the body, why take supplements?

A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.

Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.

Q. How does CoQ10 help people with Parkinson’s disease?

A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.

A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.

Participants were Divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.

The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.

The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.

Q. What were the results of clinical research on Huntington’s Disease?

A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.

Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.

Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.

Q. What other diseases could benefit from CoQ10 supplementation?

A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.

In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.

ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.

Q. Can taking CoQ10 prevent neurodegenerative disease?

A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.

Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.

Q. How much CoQ10 should I take?

A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.

CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

Q. What should I look for in a CoQ10 supplement?

A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.

Conclusion

CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.

All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.

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Date: August 21, 2006 05:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are you really Getting?

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Date: July 05, 2006 02:33 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Milk Thistle Compound Combats Lung Cancer in Mice

Silibinin, a flavonone compound found in milk thistle, helped hinder the progess of lung cancer in an animal study, according to findings published in the journal of the national cancer institute (2006, vol.98: 846-885). Researchers Divided 90 mice into six groups and injected 75 of them with cancer causing urethane and in the remaining 15, a saline solution as a control. After two weeks the normal diet, the five groups injected with urethane were fed a diet supplemented with various doses of silibinin (zero, 0.033, 0.10, 0.33, and 1.0 percent). After 18 and then 29 weeks, the silibinin groups showed between 32 and 38 percent fewer tumors and 64 to 70 percent fewer tumors, respectively, than the control group. The group with the highest dosage of 1.0 percent silibinin had 93 percent fewer large tumors than the urethane-only group. Regarding spread of cancer, the silibinin fed mice had between 41 and 74 percent fewer cancer cells that tested for spread markers.

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Date: June 07, 2006 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Syndrom Healing and 5-HTP

Boomer Breakthrough – Keeping in the Game

If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves.

Mood, Anxiety and Depression

Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use.

How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels.

Serotonin the Antiaging Neurotransmitter

Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were Divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients.

Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period.

5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin.

It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia.

Pain, Per-menopause and PMS

5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants.

Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability.

Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller.

Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety.

Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain.

Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.

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Date: December 18, 2005 09:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Keto - Anti-Aging and Antioxidant Protection

7-Keto

“Anti-Aging and Antioxidant Protection”

The Fountain of Youth Discovered in Wisconsin

It turns out that Ponce de Leon was looking in the wrong place for the fabled Fountain of Youth. It was recently discovered – in Wisconsin! And it turns out that the Fountain of Youth isn’t really a fountain – it’s a biological compound produced in our own bodies. This compound is extremely important for the growth and development of the human body, and, as the body’s production of this substance decreases with age, the signs of aging begin to appear – weight gain, wrinkled skin, loss of muscle, loss of cognitive function, and loss of libido.

This biological Fountain of Youth was discovered by Dr. Henry Lardy and associates at the Institute for Enzyme Research at the University of Wisconsin. It’s called 7-Keto™, a metabolite of a hormone produced by the adrenal glands called DHEA (dehydroepiandrosterone). Research on 7-Keto™ indicates that it may work through a number of pathways to combat the signs of aging. Helping the body maintain a healthy weight as we age greatly improves overall health and longevity and is one of the strongest benefits discovered for 7-Keto™ to date.

Unfortunately, because 7-Keto™ is a metabolite of DHEA, whose levels decline as we age, so to does this wonderful, natural bio-nutrient. Scientists originally looked to DHEA for improved cardiovascular vitality, and strengthened immune and brain function3. Researchers believed that declining DHEA so profoundly impacted our bodies that it could be partly responsible for the effects of aging. They hypothesized that supplementation with DHEA could sustain hormone levels and stave off many of the degenerative changes we collectively call aging. But there was a catch. Because DHEA is converted into sex hormones, people taking supplemental DHEA would sometimes experience the frightening, unwanted side effects associated with hormone supplementation.

In 1989, Dr. Lardy and his colleagues set out to solve the mystery of eliminating DHEA’s side effects by examining all of the constituents that make up DHEA. Ten long years of research unearthed hundreds of DHEA derivatives, which were developed and tested continuously, until one derivative rose above all the others – a metabolite that was incredibly bio-active and far more promising than any other substance they’d tested. That metabolite is 7-Keto™. 7-Keto™ outperformed DHEA and other metabolites in immune modulation, memory enhancement and thermogenesis and, more importantly, without any adverse side effects3.

The most significant benefit of 7-Keto™ supplementation is its ability to support healthy body weight. Obesity is a major contributing factor in a number of serious medical conditions. A recent study assessed the effectiveness of 7-Keto™ on weight loss and body fat loss. Participants were Divided into two groups; one group received 100mg of 7-Keto™ twice daily and the other a placebo. Both groups exercised three times per week. At the end of the study, researchers noted a statistically significant reduction in body weight and body fat only in the 7-Keto™ group. Researchers concluded that 7-Keto™ was three times more effective than diet and exercise alone in promoting weight and fat loss1,2,7. Preliminary research also indicates that 7-Keto™ may support healthy immune and nervous systems. One study measured the effects of 7-Keto™ on memory function. Subjects were given a single dose of a substance that inhibits nerve cell communication and causes shortterm memory loss. Afterwards subjects were given a single dose of 7-Keto™. Results showed that 7-Keto completely reversed the memory impairment, suggesting that 7-Keto™ supports memory retention6.

Another study gauged 7-Keto™’s ability to support immune system function. Interleukin 2 (IL2) is a substance produced by T lymphocytes that causes an increase of disease fighting white blood cells. White blood cells were taken from healthy volunteers and introduced into a solution that contained 7-Keto™ for 24 hours. When the cultures were tested for heightened IL2 production. 7-Keto™ was shown to augment IL2 production by a statistically significant 68%4.

NOW® 7-Keto™ is a well-researched and patented form of this amazing product that’s supplied by the Humanetics Corporation. Humanetics 7-Keto™ has been proven safe and well-tolerated in doses up to 200mg5. Research is clear, the rate at which we age can be influenced by the diet and lifestyle choices we make. One very smart choice would clearly be adding NOW 7-Keto™ to your diet.

References

1) 7-Keto™: The Key to Healthy Aging – Scientific Support; Humanetics Corporation, 1999
2) Garbis, Spiro; 7-Keto™ DHEA; internal meta-analysis, 2000
3) Sahelian, Ray, M.D.; DHEA: A Practical Guide; Avery Publishing, 1996
4) Lardy, H. et.al. Dehydroepiandrosterone and 7-Keto™ DHEA Augment Interleukin 2 (IL2) Production by Human Lymphocytes In Vitro, 5th Conference on Retroviruses and Opportunistic Infections, February 1-5, 1998, Chicago, IL
5) Davidson, M.H. et. al. Clinical Safety and Endocrine Effects of 7-Keto™ DHEA; Presented at Experimental Biology 98 (Conference), April 19-22, 1998, San Francisco, CA
6) Shi, J. et. al. The Effect of 7-oxo- DHEA acetate on memory in young and old C57BL/6 mice; Steroids 65 (2000); 124-129
7) Colker, C. et. al. Double-Blind, Placebo-Controlled, Randomized Clinical Trial Evaluating the Effects of Exercise Plus 3-Acetyl- 7-oxo-dehydroepiandrosterone on Body Composition and the Endocrine System in Overweight Adults; Journal of Exercise Physiology online; Vol. 2, No. 4, October, 1999

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Date: December 08, 2005 04:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Co-Enzyme B-Complex Fact Sheet

Co-Enzyme B-Complex Fact Sheet

LIKELY USERS: People with poor digestion or low stomach acid, People needing ENERGY, People desiring metabolism support.

KEY INGREDIENTS: CoEnzyme B-Vitamins plus synergists

MAIN PRODUCT FEATURES: B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as cofactors in biochemical reactions. NOWR Co-Enzyme B-Complex contains B Vitamins already in their active or "Coenzyme" forms. This enables the body to use them more quickly and efficiently because, once absorbed, they are transported directly to their site of action, requiring no conversion. 1

B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes 1, 2. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as coenzymes in biochemical reactions 1, 2.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOWR Co-Enzyme B-Complex tablets are enteric coated to enhance bioavailability by allowing delivery to intestinal absorption sites intact, unharmed by stomach acids.2 Our Quality department had to qualify several new ingredients for this formula.

This formula is enhanced with added Coenzyme C10 (CoQ10), Alpha Lipoic Acid, Betaine (TMG), Vitamin C, and both coenzyme forms of B-12 (Methylcobalamin and Dibencoside) and is suitable for vegetarians and vegans.

SERVING SIZE & HOW TO TAKE IT: Two tablets daily, preferably in Divided doses. This enteric-coated tablet is best to take between meals (one or more hours before a meal or hours after a meal), as it has an acid-resistant coating that dissolves beyond the stomach and needs to transit quickly past the stomach.

COMPLEMENTARY PRODUCTS: Vitamin C, TMG (Betaine), Lecithin (Choline, Inositol)

CAUTIONS: None.

SPECIFIC: Please discuss your use of B-Vitamins with your physician, especially if you are using any medications.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Shils ME, Olson JA, Shike M (eds.) (1994) Modern Nutrition in Health and Disease, Eighth Edition. Chapters 20-26, 28, 30. Lea & Febiger Philadelphia.
2. Chang EB, Sitrin MD, Black DD (1996) Gastrointestinal, Hepatobiliary, and Nutritional Physiology. Chapter 9, Absorption of Water-Soluble Vitamins and Minerals. Lippincott-Ravin, Philadelpia

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Date: July 27, 2005 11:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Best Lutein Featuring Biolut Marigold Ext., 60 VC

Benefits
• Maintains Healthy Visual Function*

It has been well established that lutein is present in high concentrations in the retinal tissue of the human eye. However, a study was conducted in human volunteers to determine whether taking lutein in supplement form actually increased the density of the carotenoid pigments present in the macula. In this study of eight individuals, researchers estimated the density of the macular pigments prior to having each individual take 10 mg of lutein daily in supplement form for 12 weeks. Plasma lutein concentrations were measured at 4-week intervals. During the course of the study, plasma levels increased five-fold from pre-supplement measures. It was also shown that macular pigment density increased by an average of 5.3% after 4 weeks due to increased deposition of lutein in optical tissues.1

A second study compared the oral bioavailability of esterified lutein, the form in Best Lutein, versus non-esterified lutein in 18 human volunteers. Serum levels of lutein were measured at particular timepoints after consumption of a single dose of lutein. Researchers found that in these individuals, the lutein ester formulation was nearly 62% more bioavailable than non-esterified lutein, as determined by a higher mean area under the curve (AUC) and higher serum concentrations.2

A study was also conducted to investigate the possible role of specific nutrients in protecting the lens of the eye against aging, a risk factor for compromised visual function. The study was comprised of 376 individuals aged from 18 to 75. Of the nutrients measured, it was found that the lenses of individuals with higher concentrations of lutein and zeaxanthin showed less of an effect from the aging process. The investigators concluded that these carotenoids may play a protective role in supporting the maintenance of healthy vision.3

In addition, a double-blind placebo controlled trial was performed in ninety individuals who had signs of compromised visual function. Individuals were Divided into three groups and received either 10 mg lutein, 10 mg lutein plus a multivitamin/multimineral formulation, or placebo for 12 months. In both the lutein and lutein plus other nutrients groups, improvements were seen in mean eye macular pigment optical density, visual acuity and contrast sensitivity. No improvements were noted in the placebo group.4 These results demonstrate lutein’s beneficial effect on maintaining healthy visual function.

• Potent Antioxidant Protection*

Most of the beneficial effects of lutein are ascribed to its potent free radical scavenging abilities. It is well-known that lutein is a carotenoid related to beta-carotene and possesses antioxidant activity against a number of reactive oxygen species.5

More direct evidence for the free radical scavenging activity of lutein is found in studies of its effects on human lens epithelial cells. Cell cultures were exposed to ultraviolet light after pretreatment with lutein or alpha-tocopherol. Both nutrients were found to reduce ultraviolet-induced damage to lens epithelial cells. However, lutein was shown to have significantly higher photoprotective activity than alpha-tocopherol6, demonstrating its potential as a high-powered antioxidant.

A further review of the mechanisms of lutein in conferring a protective role reveals evidence for its antioxidant activity in various body tissues. Lutein has been shown to be an effective antioxidant in vitro as well as in experimental models of a number of body systems.7

• Diverse clinical benefits*

Evidence from various experimental trials suggests that lutein may play a protective role on the circulatory and cardiovascular systems. Its antioxidant activity may also extend to the heart, skin, lungs and blood vessels, making it a nutrient with diverse clinical benefits. Lutein possesses the ability to promote the health of many body tissues.8 Safety

Suggested Adult Use: One capsule daily, or as directed by a health care professional. Take with or without food.

Scientific References
1. Berendschot TT, et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Opthalmol Vis Sci. 2000 Oct; 41(11): 3322-6.

2. Bowen PE, et al. Esterification does not impair lutein bioavailability in humans. J Nutr. 2002 December; 132: 3668-3673.

3. Berendschot TT, et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Arch Opthalmol. 2002 Dec; 120(12): 1732-7.

4. Richer S, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr; 75(4): 216-230.

5. "Lutein and Zeaxanthin". PDR Health.

6. Chitchumroonchokchai C, et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. J Nutr. 2004 Dec; 134(12): 3225-32.

7. Krinsky NI. Possible biologic mechanisms for a protective role of xanthophylls. J Nutr. 2002; 132: 540S-542S.

8. Mares-Perlman JA, et al. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002; 132: 518S-524S.

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Date: July 15, 2005 09:16 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: RECENT RESEARCH

RECENT RESEARCH

A recent study (August, 1996) exploring the effect of Hypericum perforatum on depression re vealed some fairly stunning results. The British Medical Jo u rn a l published the results of one major studies, which consisted of twenty - three randomized trials, including a total of 1757 outpatients with mainly mild or moderately seve re depressive disorders. Testing was conducted with single preparations and combinations of extracts of the plant, and with placebo and anther drug treatment. As just mentioned, the results were very promising. In all aspects of the study, Hypericum extracts were shown to be “significantly superior” to placebo and similarly effective as standard antidepressants. There were nearly twice the number, percentage-wise, of dropouts due to side effects from the standard drugs than those taking the Hypericum extracts. Side effects occurred in eighty-four patients using standard antidepressants, while only fifty patients taking the Hypericum extracts experienced side effects. And the scores on the Hamilton depression scale, which measures severity of one’s depression, showed those taking Hypericum treatments scored slightly higher than those taking the standard antidepressant and significantly higher than those taking the placebo. 9 This study provides some firm ground for St. John’s wort to stand on in the treatment of depression, both in sheer numbers and its quality of treatment.

Another contemporary study, carried out in 1995 by Witte, et. al, showed the Linde study to be accurate in its findings. This particular study, carried out as a multicenter, placebo-controlled double-blind trial, used a highly concentrated Hypericum preparation to treat ninety-seven outpatients. The course of the illness was assessed with the Hamilton Depression Scale, the von Zerssen Depressivity Scale and the Clinical Global Impression Scale. The authors of the study noted this in their abstract:

Treatment resulted in an appreciable improvement in the symptoms of depression, and the seventy percent response rate (n=43) corresponded to that of chemical antidepressants. The preparation also showed an anxiolytic effect. The substance [hypericum] was extremely well tolerated, and no side effects were reported by any of the patients.10 Again, this study’s findings correlate that of the Linde and other studies in that treatment with Hypericum is at least as effective as standard synthetic antidepressants without producing near the number of side effects.

The Nursing Times also reported on recent findings dealing with Hypericum’s effect on depression. Stating that psychiatric medications are notorious for their undesirable side effects, and that the need for safer antidepressants is widely acknowledged, the blurb refers to a double-blind study, done by G. Harrer and H. Sommer (published in Phytomedicine, 1994 (1): 3-8), using St. John’s wort on 105 patients experiencing mild to moderate depression. They were aged twenty to sixty-four and had diagnoses of “neurotic depression or temporary depressive mood.” Patients were Divided into two groups and monitored over four weeks, with one group receiving 300 mg of Hypericum extract three times daily and the other group receiving a placebo. All patients received psychiatric evaluations before the start of the study and after two and four weeks of treatment.11

The results of the study support the findings of other recent studies dealing with Hypericum and depression: 67 percent of the Hypericum group had responded positively to the treatment without any adverse side effects, whereas only 28 percent of the placebo group displayed any improvement. Harrer and Sommer state that the patients treated were experiencing strictly mild forms of depression; combining this with the study’s results and the results of other studies suggest that Hypericum treatment can be a very effective treatment for mild to moderate depression without severe side effects. The authors themselves even recommended that Hypericum should be considered as a remedy of choice. 12

These and other studies point to the strong possibility of using St. John’s wort, and specifically hypericin, on a wide scale to treat various forms of depression. Linde’s study suggests that St. John’s wort may have its most valuable asset in that of few or no side effects, something many sufferers of depression are very concerned about. The authors do note, however, that more research is necessary, especially in determining the severity and nature of depression, length of treatment, treatment dosage, preparation of Hypericum extracts, and occurrence of long-term side effects. Nevertheless, the results of this study and others are extremely promising for the millions of those who suffer from depression.

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Date: July 08, 2005 10:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cinnamon may control sugar levels...

Best Cinnamon

Cinnamon,
a staple ingredient in apple pie, has remained one of the
world's favorite spices throughout recorded history. The
evergreen cinnamon tree (Cinnamomum verum), considered to be
true cinnamon, is native to Sri Lanka. Chinese cinnamon
(Cinnamomum cassia or Cinnamomum aromaticum), the cinnamon most
commonly sold in the U.S., goes by the name “Cassia.” Usage of
cinnamon in Chinese medicine is said to date back over 4,000
years. Mentioned in the Bible, cinnamon was imported to Egypt
and Europe from the Far East by 500 B.C. In addition to its
value as culinary spice, cinnamon has traditionally been
utilized as a folk medicine for colds and minor digestive
complaints. True cinnamon and cassia are very similar; cassia
has a more pungent flavor. Cassia buds can be found in potpourri
and used as a flavoring agent in sweets and
beverages.1

Recent research has revealed that constituents in
cinnamon bark called procyanidin Type-A polymers help maintain
the body's ability to metabolize glucose in a healthy way.* Best
Cinnamon Extract is Cinnulin PF®, a patented, water extract of
Cinnamon that contains Type-A polymers. Cinnulin PF® is a
registered trademark of Integrity Nutraceuticals International
and is manufactured under US Patent #
6,200,569.

Benefits

Use as Part of Your Diet to Help
Maintain a Healthy Blood Sugar Level*

In Vitro and Animal
Studies

Research has revealed that a number of herbs and
spices have insulin-like activity.2 In a study by the U.S.
Department of Agriculture (USDA), cinnamon demonstrated the
greatest ability to stimulate cellular glucose metabolism among
49 botanicals tested.3

In a 2001 study, researchers at the
USDA's Human Nutrition Research Center showed that bioactive
compounds in cinnamon trigger an insulin-like response in fat
cells.4 These compounds stimulated glucose uptake into cells and
increased glycogen (stored glucose) production via activation of
the enzyme, glycogen synthase.

The bioactive compounds in
cinnamon appear to potentiate insulin activity at the level of
the cell receptor for insulin. It has been shown that insulin
resistance involves down regulation of “insulin signaling”
characterized by dephosphorylation of the receptor.5 Enzymes
called “protein tyrosine kinases” (PTPases) are believed to
decrease receptor phosphorylation, and increased PTPase activity
has been observed in insulin resistant rats.6 Cinnamon compounds
have demonstrated the in vitro ability to inhibit PTP-1 and
increase autophosphorylation of the insulin receptor.7

In a
recent animal study, cinnamon (cassia) extract was administered
to rats for three weeks. Following this, the rats were infused
with insulin and glucose to assess their insulin response.
Increased phosphorylation of the insulin receptor was observed
in skeletal muscle of these rats, suggesting that cinnamon has
the ability to potentiate insulin function by normalizing
insulin signaling, leading to improved uptake of glucose into
skeletal muscle.8

Until recently, the precise molecular
structure of the bioactive compounds in cinnamon had not been
clearly defined. The USDA has now determined that the bioactive
compounds in cinnamon are water-soluble procyanidin Type-A
polymers of catechin and epicatechin. In a 2004 study, type-A
polymers were isolated from cinnamon and characterized by
nuclear magnetic resonance and mass spectroscopy. Type-A
polymers were found to increase in vitro insulin activity by a
factor of 20. Type-A polymers also exhibited antioxidant
activity, as measured by inhibition of free radical production
in platelets. These results suggest that, in addition to
regulating glucose metabolism, cinnamon may help protect cell
membranes by controlling the lipid peroxidation associated with
disruptions in insulin function.9

HUMAN CLINICAL TRIALS

The effect of cinnamon on glucose and blood lipids
levels on people with type 2 diabetes was tested in a recent
randomized, placebo-controlled trial. A total of 60 subjects
were Divided into six groups administered 1, 3, or 6 grams of
cinnamon daily, in 500 mg capsules, or equal numbers of placebo
capsules.

The cinnamon or placebo capsules were consumed for
two periods of 20 days each. Serum glucose, triglyceride,
cholesterol, LDL cholesterol and HDL cholesterol were measured
after 20 days, 40 days and again at the end of a 20-day wash-out
period, during which neither cinnamon nor placebo was
consumed.

In all three cinnamon groups, statistically
significant reductions in blood glucose levels occurred, with
decreases ranging from 18 to 29 percent. Interestingly, glucose
levels remained significantly lower after the 20-day wash-out
period (60 days from the study start) only in the group that
took the lowest cinnamon dose (1 gram daily). The placebo groups
showed no significant changes.

Decreases in triglyceride
levels ranging from 23 to 30% were observed in all three
cinnamon groups after 40 days. When the study ended at 60 days,
triglyceride levels remained lower than at the study start in
the 1 and 3 gram cinnamon groups, but not in the group taking 6
grams daily. Cholesterol reductions also occurred with the three
cinnamon doses, with decreases ranging from 13 to 25% that were
maintained at the study end. For LDL, the 3 and 6 gram cinnamon
groups showed significant reductions from 10 to 24%, while in
the 1 gram cinnamon group, non-significant reductions occurred
after 40 days; LDL levels continued to decrease, reaching
statistical significance at 60 days. With respect to HDL,
significant increases were seen only in the 3 gram cinnamon
group after 20 days; non-significant changes occurred in the 1
and 6 gram groups after 40 days.

The overall results of this
trial demonstrate that cinnamon exerts a beneficial effect on
blood glucose and lipid levels in people with type 2 diabetes,
at daily intakes of 1 gram, and that this low dose is equally
efficacious as are the higher doses of 3 and 6
grams.10

Safety

The various species of cinnamon are
classified as GRAS (generally regarded as safe) herbs.11 The
Botanical Safety Handbook lists Cinnamomum cassia a “Class 2b”
herb; not to be used during pregnancy.12 The water-soluble
cinnamon extract is largely free of the lipid-soluble components
of cinnamon most likely to be toxic at high dose of cinnamon and
long-term consumption of the herb.9

*This statement has not
been evaluated by the Food and Drug Administration. This product
is not intended to diagnose, treat, cure or prevent any
disease.

Scientific References

1. Manniche, L. An Ancient
Egyptian Herbal. 1989, Austin , TX : University of Texas
Press.

2. Khan A, Bryden NA, Polansky MM, Anderson RA.
Insulin potentiating factor and chromium content of selected
foods and spices. Biol Trace Elem Res 1990;24(3):183-8.

3.
Broadhurst CL, Polansky MM, Anderson R. Insulin-like biological
activity of culinary and medicinal plant aqueous extracts in
vitro. J Agric Food Chem 2000;48(3):849-52.

4. Jarvill-Taylor
KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from
cinnamon functions as a mimetic for insulin in 3T3-L1
adipocytes. J Am Coll Nutr 2001;20(4):327-36.

5. Nadiv O,
Shinitzky M, Manu H, et al. Elevated protein tyrosine
phosphatase activity and increased membrane viscosity are
associated with impaired activation of the insulin receptor
kinase in old rats. Biochem J. 1998;298(Pt 2):443-50.

6.
Begum N, Sussman KE, Draznin B. Differential effects of diabetes
on adipocyte and liver phosphotyrosine and phsophoserine
phosphatase activities. Diabetes 1991;40(12):1620-9.

7.
Imparl-Radosevich J, Deas S, Polansky MM, et al. Regulation of
PTP-1 and insulin receptor kinase by fractions from cinnamon:
implications for cinnamon regulation of insulin signalling. Horm
Res 1998;50:177-182.

8. Qin B, Nagasaki M, Ren M, et al.
Cinnamon extract (traditional herb) potentiates in vivo
insulin-regulated glucose utilization via enhanced insulin
signaling in rats. Diabetes Res Clin Pract
2003;62(3):139-48.

9. Anderson R, Broadhurst CL, Polansky MM,
et al. Isolation and characterization of polyphenol type-A
polymers from cinnamon with insulin-like biological activity. J
Agric Food Chem 2004; 52(1):65-70.

10. Khan A, Safdar S,
Muzaffar M, et al. Cinnamon improves glucose and lipids of
people with type 2 diabetes. Diabetes Care
2003;26(12):3215-18.

11. Duke, JA. Handbook of Phytochemical
Constituents of GRAS Herbs and Other Economic Plants. 1992. Boca
Raton, FL: CRC Press.

12. Botanical Safety Handbook. American
Herbal Products Association. McGuffin M, et al., eds. 1997; Boca
Raton , FL : CRC Press.

Acting as a biochemical
"super-thiamin," it does this through several different cellular
mechanisms, as discussed below.

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Vitanet ®

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Date: June 29, 2005 01:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CHOLESTEROL RESCUE - Maintain Your Cholesterol Wellness

CHOLESTEROL RESCUE

You live in a fat-drenched, fast food world, propped up by diets loaded with processed foods that stimulate your body to create excess bad cholesterol – or low-density lipoproteins (LDL). Your busy life is full of stress, and devoid of time for proper exercise. There are three ways to deal with cholesterol in the body, but a seemingly infinite number of lifestyle and hereditary elements that affect LDL levels. Is it any wonder you find yourself in danger of developing unwanted cholesterol levels? Source Naturals is devoted to helping you. So we developed CHOLESTEROL RESCUE as a comprehensive solution to help you keep cholesterol levels in the normal range. CHOLESTEROL RESCUE uses only natural ingredients, clinically researched to effectively maintain healthy cholesterol levels. It is scientifically formulated with the triple action of three ingredients that target the ways you can deal with your cholesterol concerns; combining the naturally occurring polymethoxylated flavone (PMF) and tocotrienol action of Sytrinol™ with the action of plant sterols. Research suggests that daily consumption of 800 mg of plant sterols, taken with food in two Divided doses as part of a diet low in saturated fat and cholesterol, may reduce the risk of coronary heart disease. Source Naturals offers CHOLESTEROL RESCUE as part of our ongoing commitment to providing you with high quality natural supplements to support your healthy lifestyle.

Cholesterol & Your Body

On average, humans ingest approximately 300mg of cholesterol per day. Though an important part of a healthy body, a high level of cholesterol in the blood might be out of the normal range. Cholesterol is transported in your system by lipoproteins. There are two kinds of lipoproteins in your body, but the low-density lipoproteins, or LDL, are the major factors in developing unwanted cholesterol levels. If there are high levels of LDL circulating in your bloodstream, it can undergo oxidation by free radicals in the artery walls, which can then become trapped as imbalanced deposits. These deposits can build up, reducing critical blood-flow. CHOLESTEROL RESCUE has been specially developed to reduce LDL levels using two different methods: inhibiting the synthesis of cholesterol in the liver, and reducing the absorption of dietary cholesterol.

The Plant Sterol Effect

Sterols are an essential component of the cell membrane, and are produced by both plants and humans. While the most common sterol produced in humans is cholesterol, plants produce phytosterols, or plant sterols. Using a complex compound of plant sterols similar to cholesterol with only slight molecular differences, CHOLESTEROL RESCUE has been formulated to balance the amount of dietary cholesterol your body absorbs.

Plant sterols have long been known to inhibit the uptake of both dietary and bile-produced cholesterol in the intestines. The most plausible theory behind this is that, because of the similarity between plant sterols and cholesterol, the body cannot properly distinguish between the two during the absorption process, thereby displacing the uptake of cholesterol into your system. Research suggests that daily consumption of 800mg of plant sterols, taken with food in two Divided doses as part of a diet low in saturated fat and cholesterol, may reduce the risk of coronary heart disease.

Sytrinol™ For Heart Health

CHOLESTEROL RESCUE also contains SYTRINOL™, a proven natural alternative for maintaining cholesterol wellness. The patented blend of citrus polymethoxylated flavones (PMFs) and tocotrienols has been clinically shown to promote cardiovascular health by supporting normal cholesterol production by your liver, helping balance triglyceride production, and providing powerful antioxidant protection. The PMFs promote normal cholesterol levels by inhibiting both the production of cholesterol precursors, such as cholesteryl esters, and the activity of HMG CoA Reductase, an enzyme that synthesizes cholesterol in the liver. These PMFs can also balance the body’s production of triglycerides by inhibiting your liver’s triglyceride producing enzyme, diacylglycerol acetyltransferase. Tocotrienols help break down cholesterol building blocks, interfere with cholesterol production, and provide critical antioxidant protection. Because cholesterol becomes problematic when oxidized, the powerful antioxidant action of tocotrienols can help prevent the conditions that may affect your cardiovascular circulation.

Spearheading the Wellness Revolution in Cholesterol Defense

With so many ways to develop undesirable cholesterol levels in your body, you need to be proactive in maintaining your good health. In our on-going dedication to your wellness, and a commitment to delivering the benefits of our high quality supplements to the natural products marketplace, Source Naturals has produced a scientifically formulated blend of three effective ingredients in fighting unwanted cholesterol. Combining a comprehensive formula of allnatural components, clinically researched for promoting cardiovascular health, CHOLESTEROL RESCUE is available now at your local health food store.

References
Guthrie N, Kurowska EM. Anticancer and Cholesterol-lowering activities of citrus flavonoids. Handbook of Nutraceuticals and Functional Foods. (Wildman, R.E.C., ed), CRC Press, Boca Raton, FL. 2001. 113-126. Packer L, Weber SU, Rimbach G. Molecular aspects of alphatocotrienol antioxidant action on cell signaling. Symposium: Molecular Mechanisms of Protective Effects of Vitamin E in Atherosclerosis. American Society for Nutritional Sciences. 2001. 131:369S-373S. Hicks KB, Moreau RA. Phytosterols and phytostanols: functional food cholesterol busters. Food Technology. 2001. 55:63-67. Middleton Jr E, Kandaswami C, Theoharides TC. The effect of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacological Review. 2000. 52:673-751. Child P, Kuksis A. Critical role of ring structure in the differential uptake of cholesterol and plant sterols by membrane preparations in vitro. Journal of Lipid Research. 1983. 24: 1196-1209

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Vitanet ®

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Date: June 25, 2005 08:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CHITOSAN SAFETY

CHITOSAN SAFETY

Chitosan is not only very useful, it is also very safe. Chitosan has been used extensively in nummerous industrial, health, and food applications.66,71 Nevertheless, all substances when taken improperly or in gross excess can be detremental to our well-being. For example, water is normally safe when swallowed. On the other hand, breathing large amounts of water can be deadly. Similarly breathing air is relatively safe whereas intraveneous injections of air are usually fatal. To determine the relative safety of various foods, scientists run experiments to determine the food’s toxic level or LD50. Chitosan has been found to have an LD50 of over 16 grams/day/kg body weight in mice.122 Chitosan is a fiber which expands to form a gel in the acidic environment of the stomach. The problems encountered with extremely high doses of chitosan were caused by gastric dehydration and impaction due to the expansion of the fiber.123 To put these data in context, the authors compared Chitosan to common sugars stating “[I]t appears that chitosan is less toxic than these substances.”122 Mice are not men. For safety purposes data gathered in mice is Divided by 12 to get the human equivalent.124 The relative LD50 in humans then would be 1.33 grams/day/kg. Given that an average person weighs 150 pounds or 70 kg, this means that the toxic amount for a person would be greater than 90 grams per day. Conservatively, one could feel very confident below the 10% level, or 9 grams per day. Clinical studies have used amounts in the 3-6 grams per day range with no adverse effects. As with any fiber, a person is well advised to drink plenty of water. Changing our diets affects our colon function. Constipation or diarrehea may occur in some persons depending on their individ-ual constitutions and on how well the Chitosan supplement was originally formulated. Even though Chitosan is not digestible by our enzymes, it can and is degraded by soil and water microorganisms. This makes Chitosan environmentally friendly. This was recently acknowledged by the US Environmental Protection Agency when it exempted Chitosan from tolerance level testing.68 Any breakdown of chitosan by our colon microflora would release D-glucoseamine which is itself a wonderfully beneficial nutrient for osteoarthritis sufferers.125 Because Chitosan can bind lipids and certain minerals, it is best to take essential fatty acid supplements, fat soluble vitamins and mineral supplements separate from Chitosan. Taking Chitosan with D- or L-ascorbic acid helps increase the amount of fat bound and decrease the loss of minerals. 77,126

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Date: June 21, 2005 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....

GPC (GlyceroPhosphoCholine): Versatile Life Support Nutrient

Parris Kidd, Ph.D.

GPC or GlyceroPhosphoCholine (pronounced gli-sero-fos-fo-ko-lean) is a nutrient with many different roles in human health. It reaches extremely high concentrations within our cells, and its abundance in mother's milk suggests it is crucial to life processes. Clinically, GPC has been most intensively researched for its brain benefits. Biologically, it has great importance for the skeletal "voluntary" muscles, the autonomic nervous system, kidneys, liver, and reproductive organs. GPC goes beyond being a brain nutrient; it is a nutrient for vitality and long life.

Marked Benefits to the Brain

As a dietary supplement, GPC's brain benefits are unique. It boosts mental performance in healthy young people, as shown by three double-blind trials. In trials on middle aged subjects, GPC improved several physiologic measures of mental performance: reaction time, visual evoked potential, and EEG delta slow waves. In the elderly, GPC improves mental performance and provides noticeable revitalisation. In 11 human trials with 1,799 patients, memory, attention, and other cognitive measures improved. So did mood (including irritability and emotional lability), and patients often developed renewed interest in relatives and friends. GPC was well tolerated, and generated no bad drug interactions. A large trial on elderly subjects with memory challenges published in 2003 concluded GPC had significant benefits for these individuals.

GPC Supports Normal Brain Function

Circulatory deprivation or surgery can challenge healthy brain function. GPC can speed recovery and support improved quality of life. In four trials with GPC on 2,804 subjects who experienced difficulties under these circumstances, up to 95% showed good or excellent improvement. GPC consistently improved space-time orientation, degree of consciousness, language, motor capacity, and overall quality of life. The investigators concluded GPC offered marked benefits, with an excellent benefit-to-risk profile. Up to half of patients who survive bypass surgery experience problems with memory and other mental performance. A double-blind trial conducted with bypass survivors for six months determined that the GPC group had no remaining memory deterioration, while the placebo group failed to improve.

GPC Works Through Multiple Mechanisms

GPC supports human health through a variety of mechanisms:

1. It helps keep choline and acetylcholine available to the tissues. Choline is an essential nutrient and GPC appears to be the body's main choline reservoir. GPC in mother's milk represents the baby's main source of dietary choline. Acetylcholine (ACh) is an important substance employed extensively throughout the body. ACh is a major brain transmitter; the motor nerves use ACh to drive the skeletal ("voluntary") muscles; the autonomic nervous system uses it to pace all the organs. ACh is also central to mental and physical endurance, and mind-body coordination.

2. GPC is a major cell-level protectant, not as another antioxidant but in pivotal roles of osmotic pressure regulator and metabolic antitoxin. GPC for osmotic regulation can reach very high concentrations in the kidney, bladder, liver, brain, and other organs. As metabolic protectant, GPC shields proteins against urea buildup.

3. GPC is a major reservoir for cell membrane omega-3 phospholipids. These substances are the major building blocks for cell membranes. Enzymes couple GPC with the omega-3 fatty acid DHA, to make the phospholipid PC-DHA. This makes membranes especially fluid, enabling membrane proteins to perform with better efficiency. GPC produces PC-DHA in the skeletal muscles, wherein fluidity is essential for contraction. Muscles that function abnormally can show GPC deficiency.

4. GPC contributes to both male and female in reproduction. As spermatozoa mature, GPC is used to make PC-DHA that makes their membranes fluid to enable motility. With men, the lower their semen GPC the greater the likelihood of poor sperm motility and with it, infertility. Once semen is inserted into the female, an enzyme in uterine secretions breaks down the semen's GPC into substances that energize the sperm to achieve fertilization.

Dosing, Safety, Tolerability, Compatibility

Oral intake of GPC in the clinical trials was usually 1,200 milligrams (mg) per day, taken early in the day on an empty stomach. A reasonable dietary supplementation regimen is 1200 mg/day, taken in Divided doses (AM and PM) between meals for 15-30 days, and thereafter 600 mg/day for maintenance. Symptomatic subjects can take 1200 mg/day until adequate improvement is achieved. Young, healthy subjects may experience benefit from daily intakes as low as 300 milligrams. GPC is very safe, being compatible with vitamins and nutrients and with pharmaceuticals. In clinical trial comparisons, GPC's benefits surpassed the nutrients acetylcarnitine and CDP-choline.

GPC: Nutrient for All Ages

GPC is unmatched for its support of active living and healthy aging. In some 23 clinical trials GPC improved mental performance in all functional categories. GPC can revitalize the aging brain, facilitating growth hormone (GH) release and boosting nerve growth factor actions. GPC's ample presence in human mother's milk suggests it could be conditionally essential. By supporting mental integrity, mind-body integration, the autonomic system, and the body's other organs, GPC enhances the active lifestyle. GPC is remarkable nutritional support for optimal health at any age.

Parris M. Kidd, PhD is a cell biologist trained at the University of California, Berkeley and San Francisco. Since entering the dietary supplement field in 1983, he has published many in-depth reviews of integrative medicine in the journal Alternative Medicine Reviews, and is science columnist for totalhealth magazine. Dr. Kidd is internationally recognized for his accomplishments in dietary supplement product development, documentation and quality control.

Disclaimer: the above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider.

--
Vitanet ®

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Date: June 18, 2005 09:07 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Anti-Aging Nutrients

Anti-Aging Nutrients by Edward C. Wallace, DC, ND Energy Times, February 3, 2000

What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful, easy feeling.

How Do We Age?

Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.

The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.

Programmed Cell Theory

In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.

Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.

Free Radical/Oxidative Stress Theory

The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents.

Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.

DNA Repair Theory

Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.

What Can We Do?

The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.

In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."

Antioxidant Protection

Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.

Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.

In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.

Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.

Nutrition Deficiencies

A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).

When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).

A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.

Longevity Diets

A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460).

Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers (Epidemiology 3[5], 1992: 389-391).

Staying Alive

Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.

Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).

In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.

Longevity and Exercise

Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.

Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.

The Treadmill of Life

The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying (JAMA 273 [14], April 12, 1995: 1093-1098).

Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.

Longevity Supplementation

Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.

Toning Down Enzymes

Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).

In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.

The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).

Vitamins E & C

A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.

Chronological Age Vs.Biological Age

Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems.

In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.

Similar Relationship

A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less.

And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers Divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.

The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).

Carotenoids

When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.

Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119[1], Jan. 1989: 112-115).

Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.

Flavonoids

Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.

Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).

Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.

Amino Acid Health

Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.

Attitude & Behavior

Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).

In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).

Longevity at Last

While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of longer life. And by staying healthier, your old age will be more enjoyable, too.

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Vitanet ®

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Date: June 14, 2005 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Good Hydration

Good Hydration by Lisa James Energy Times, June 17, 2004

Ah summertime, and the living is lovely: ocean fragrances wafting on a summer wind, the summer sun warming the body and relaxing the mind.

But all that sun and wind can dry your summer skin, making it uncomfortable and parched-looking. Moisture counteracts the discomforts that summer elements can bring, allowing your fresh, dewy look to shine through. Knowing how to hydrate your skin is the key.

Skin Structure

Skin consists of three layers, each with a different function:

• The topmost skin layer, the epidermis, protects the body against the outside world. It contains melanocytes, pigment-bearing cells that determine skin color and help guard against sun damage. The epidermis is also equipped with immune cells that guard the body against foreign substances. The epidermis is further Divided into five separate sublayers. Cells are formed at the basal cell layer on the bottom; they then push their way upward until they reach the surface, called the stratum corneum, in a process that takes roughly 28 days. As the skin cells mature, they produce a tough protein called keratin, which also forms the structure of hair and nails.

Natural Moisturizers

Do you have dry skin? How well your skin holds moisture depends on the arrangement of cells within the stratum corneum. Fat contained in this layer, as well as natural moisturizing factor (made by the epidermis), also keeps skin moist. Unfortunately, as you age, the amount of natural moisturizing factor produced by your skin decreases.

Skin Care 101

Obviously, anything that affects the all-important epidermis can dry out your skin-sun and wind both rob skin of moisture. For starters, just say no to tobacco. Smoking tightens the skin's abundant blood vessels; this reduces the flow of oxygen and nutrients, creating dryness. Smoking also breaks down elastin, the protein that gives skin its flexibility. The next step is to add water from within. " It takes at least six to eight cups of pure water each day to keep the skin and body well hydrated," notes Jeanette Jacknin, MD, board-certified dermatologist and author of Smart Medicine for Your Skin (Avery/Penguin).

Bathtime Tips

At the same time, be careful about how you bathe your skin. Bathing or showering for too long, or using water that's too hot, can actually cause your skin to lose moisture for two reasons. First, prolonged bathing washes away the oils that help lock moisture in; second, it encourages your skin's own moisture to evaporate after you dry yourself off.

Before you shower or bathe, Dr. Jacknin recommends using a dry, soft-bristled brush to increase skin circulation and gently remove dead cells. Brushing in small circles, gradually move up your legs and arms, always moving towards the heart. When you do get into the tub or shower, don't scrub your skin and don't use harsh cleaning agents. Instead, go for natural cleansers that feature such skin-friendly ingredients as glycerin.

Feed Your Inner Skin

As your body's largest organ, your skin depends on the nutrients in your diet. You have to feed your skin well if you expect it to stand up to wind and sun. " Eat fish, rolled oats and ground flaxseeds frequently," recommends Dr. Jacknin. "These foods are high in omega-3 fatty acids, which help the skin retain moisture." Include other healthy oils, such as safflower and olive oil, in your meals. Supplemental omega-3s, in the form of flaxseed or fish oils, can also help.

Supplemental Skin

Various vitamins help make your skin happy and healthy. Skin growth and repair requires vitamin A, while natural vitamin E provides antioxidant protection and vitamin C promotes creation of collagen, which provides skin with its structure.

The B vitamins are essential to keeping dryness at bay; without them, the skin can crack, peel and redden. Choline, a member of the B family that helps with fat transportation within the body, is available as lecithin. Methylsulfonylmethane (MSM) is another skin-friendly nutrient. MSM provides sulfur, which the body needs to create healthy skin proteins. It also fights inflammation and encourages better blood flow.

Slake Your Skin's Thirst

A good moisturizer can help arid skin return to soft freshness. To get the most out of moisturizers, use them consistently, and start at a young age. " [M]ost people start to benefit from [moisturizers] in their twenties [when] their skin begins to dry with age," state Charles Inlander and Janet Worsley Norwood in Skin: Head-to-Toe Tips for Health and Beauty (Walker and Company). "Moisturizers boost skin health by preventing water loss from the skin."

The same antioxidant nutrients, such as vitamin C and natural vitamin E, you feed your skin from within also abound in natural moisturizers, as do an impressive variety of herbal essences and essential oils. Aloe vera, used to treat burns for centuries, helps ease inflammation, as does chamomile. Fresh-smelling lavender oil helps soothe insect bites and minor wounds. Jasmine and peppermint offset excessive oil production.

Moisturizers: Timing and Type

The ideal time to moisturize is right after a bath or shower, since that's when evaporation promotes water loss; for best results, apply while your skin is still slightly damp. But bathtime isn't the only time to consider your skin's moisture needs. Carry some moisturizer with you so you can use it every time you wash your hands, especially if you're prone to cracked cuticles and split fingertips.

Match your moisturizer to your skin type. If your skin tends to oiliness, use a water-based product; otherwise, an oil-based formulation -jojoba oil and shea butter are good choices-is fine. (Oily skin may first need a gentle astringent like lemon peel or cucumber to remove dirt and excess oil.)

Also pay careful attention to the type of moisturizer you use. Lotions are easy to apply, but may not stay on your skin as readily as creams, which may be a better choice for your face, feet and hands. By all means, enjoy the summer sun. Just make sure your skin enjoys the summer, too, by staying hydrated and happy.

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Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Truth in Labeling

Date: June 14, 2005 10:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Truth in Labeling

Truth in Labeling by Diane Stanton Energy Times, June 14, 2004

Do you or don't you read food labels when you shop? If you don't, you're missing out on a prime source of information about your meals. If you want control of your health, focus on package labels and pick your foods carefully.

The large print on food labels focus on what are called macronutrients: carbohydrates, fat and protein. Some of the smaller categories convey information about vitamins, fiber, and minerals, as well as the totals of fat and saturated fat contained in food. So, you have no excuse for claiming ignorance about your diet: the truth is in the labels.

Food labels can be confusing to the uninitiated. Go into a big food store and you can be faced with what seems to be a forest of food information: more than 15,000 labels. Add to that fact that every year more than 30,000 new food products can be introduced to the marketplace, and what you're faced with is a jungle of food labels.

That overwhelming wealth of food label information doesn't mean you should throw up your hands in dismay and give up reading and deciphering labels. You should arm yourself against that sea of labels with knowledge and, by understanding them, end your confusion and build your health.

Label History

A hundred years or so ago, food labels were only required to list the name of the food contained inside the package. The contents, quality and processes used to make the food were often a mystery. Little or no disclosure to consumers was made about how their food was created.

By the early 1920s, the federal government, via the Food and Drug Administration (FDA), began requiring food companies to list the net weight of food on labels as well as the names and addresses of food processors and distributors. Finally, by the 1970s, listing basic nutritional information was mandated in a uniform way so that shoppers could have some basis for comparing foods. Then, in 1990, the Nutrition Labeling and Education Act made major alterations to the kinds of labels that had to be included on food packages.

The FDA and the US Department of Agriculture (USDA) required significant changes to food labels that were supposed to make it easier for consumers to eat healthier diets. The labels requirements of 1994 included five major changes:

• What you may need to increase: vitamin A, vitamin C, calcium and iron

" Much more attention has been paid to what people should limit rather than the nutrients needed. The average consumer doesn't know, for instance, how much vitamin A 10% of the Daily Value is, or how much calcium 25% of the Daily Value is," Dr. Chapman-Novakofski says.

Upping Calcium Intake

In their eight-week study of people's calcium consumption (Journal of Nutrition Education and Behavior 4/04), the University of Illinois research team found that people didn't know how much calcium was in the food they ate.

After the initial part of the study, in which participants were shown how to look for calcium on labels, "the post-test revealed that the participants significantly increased their calcium intake to 821 mg per day, up from 372 mg per day," notes Dr. Chapman-Novakofski.

" That's a lot closer to the daily requirements of 1,200 mg per day for men and women over 50, 1,000 mg for men and women aged 19 through 50 and 1,300 mg per day for [youths aged] 9 to [18] years," she adds.

Parts of the Label

The first item at the top of a nutrition food label tells you the portion size that the label measures. An important point to remember: these sizes are determined individually by each manufacturer. Consequently, all of the other values on the label are measured per portion.

So, if you are comparing foods made by two different companies that employ very different portion sizes in their nutritional calculations, your label comparisons may be complicated.

Another fact to be aware of: the listed portion size may be an odd division of the food within the container and not reflect a common-sense division. For instance, some food packages are labeled as containing 2.5 portions.

And, to make things even more interesting, small boxes of candy that you might think contain barely enough for one helping may be labeled by the manufacturer as having two or more portions. As a result, if you eat the whole box, you often have to at least double the number of indicated calories, etc. to figure out the nutrients and calories you are consuming.

The section of the label that notes calories, calories from fat and percent daily values is listed under the portion size. Here you are told how many calories you consume when you devour one portion and how many of those calories are derived from fat.

This label focus on fat originated when consumers and dietitians were very concerned about Americans' fat consumption and hadn't yet switched their focus to carbohydrate consumption as a prevalent dietary health priority.

Also included on the label: the daily value percentages aimed at showing you how much out of a total day's intake of various nutrients a portion bestows upon you.

These percentage numbers are based on a theoretical analysis of a diet that contains 2,000 or 2,500 calories a day. (A notation at the bottom of the label tells you whether the calculation is based on 2,000 or 2,500.)

Carb Facts

If you've been eating a low-carb diet (or are planning this type of diet), the section of the label that lists carbohydrates may be especially useful. Under this heading, the label lists the totals for fiber and sugar.

No matter what diet you are on, dietary fiber is desirable, since it represents indigestible carbohydrates that both pass through you without conveying any calories and keep beneficial bacteria in your digestive tract healthy.

Most people want to limit their sugar totals, however, since this nutrient may raise your risk of being overweight and, when you eat a lot of it, may contribute to immune problems.

Interestingly enough, when food chemists compute what is in food, they perform lab tests known as assays to distinguish its ingredients. (The manner in which these tests are performed are very strictly regulated by the FDA.)

In fact, just about every nutrient listed on a food label is determined by laboratory test except for the carbohydrate content: the amount of water, fat, crude protein and ash are determined this way. But the total carbs are computed by simply subtracting the total of the other ingredients from the total amount of food, a kind of process of elimination.

So while fat and protein are measured with precise lab tests, carbohydrate totals are figured by the leftovers. (The water and ash, by the way, are not usually listed on food labels.)

Within the general carbohydrate group, are several categories of carbohydrates that produce very different effects in your body. These categories can be Divided into sugar, sugar alcohols, dietary fiber and a collection of various chemicals that include organic acids, flavonoids, gums, lignans and others.

According to the FDA, the food label only has to list the total carbs, sugar and dietary fiber. But some food companies now list things like sugar alcohols.

Blood Sugar Effects

Not all of these types of carbohydrates behave the same way in your body. For example, when your body digests table sugar, it turns immediately into blood sugar. So sugar and most other carbohydrate is what we call "digestible carbohydrate." Other carbs, such as sugar alcohol or glycerine, can be digested but do not turn to blood sugar. Still others, such as dietary fiber, are indigestible and pass through your body without impacting your blood sugar level.

To date, the FDA has not focused on these important biochemical differences and treats all carbohydrates alike. This means that when you look at a food label, you do not see a number for the carbs that impact your blood sugar level. To do so, simply subtract the number of grams of fiber from the total number of carbohydrate grams.

Net Carbs

Recently, the phrases "low carb," "net carb" and "impact carbs" have begun to appear on food labels. These are not defined by the FDA; they were put on labels by by companies to help consumers pick out foods that are acceptable on low-carb diets. To arrive at the total of net carbs, food companies subtract the total amount of fiber and sugar alcohol from the total carbohydrates.

Fiber Calculations

Since the body cannot digest fiber, this nutrient (which is still important for good health) is not calculated into the total amount of carbohydrates. As for sugar alcohols, while-technically speaking-these are carbs and they do have calories, they have little effect on blood sugar and usually are not counted in total carbohydrates.

According to the American Dietetic Association, people with diabetes who are managing their blood sugars using the carbohydrate counting method should "count half of the grams of sugar alcohol as carbohydrates since half of the sugar alcohol on average is digested.

" Fiber is not digested, however. If the serving of food has more then 5 grams of fiber one should subtract the grams of fiber from the total carbohydrate grams." As you can see, when it comes to food, as in most things, knowledge is power. If you want power over your health, you need power over the food you eat. The road to that power is by reading food labels. What's in the food you're eating every day may surprise you.

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Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Mane Attraction - lustrous Hair...

Date: June 14, 2005 08:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Mane Attraction - lustrous Hair...

Mane Attraction by Chrystle Fiedler Energy Times, February 12, 2004

Everyone wants thick, lustrous hair. Think of the allure attached to the locks of Samson and Lady Godiva and-fast-forward to the present-the full heads of Antonio Banderas and Julia Roberts.

" We're naturally attracted to hair as humans; it catches the light, it frames the face, we like the feel of it," says Catherine Jones, ND, LAc, a resident naturopathic physician at Bastyr Center for Natural Health in Seattle, Washington. "Fair or not, historically in many cultures, rich, thick hair has been a sign of fertility and strength."

Along with that allure, latching onto natural ways to have great-looking hair gives you the benefits of looks and health. Every hair starts with a shaft that grows from a root. "The root is contained deep within the hair follicle," says Dr. Jones. "Each one has a sebaceous or oil gland, which supplies the hair with necessary lubrication as it approaches the surface of the scalp." Each hair follicle has its own growth cycle, including a resting period, the telogen phase, when hair falls out. Because of these constant hair phases, each of us loses, on average, about 100 hairs a day.

" The number of hairs the average person loses in a day tends to increase in the fall as the leaves fall from the tree and tends to decrease in the spring as the bulbs emerge from the soil," Dr. Jones says. "We really are connected to nature." Stress-due to rapid weight loss, infection, anemia, prolonged illness, hormonal changes, hypoactive thyroid disease, autoimmune conditions, eczema or psoriasis-can influence hair growth and loss.

The Nature of Hair

Hair consists of proteins, lipids (fats), carbohydrates and pigment (gray hair has reduced pigment; white, none at all). Each shaft's structure is Divided into a medulla, a cortex and an outer cuticle. " The cuticle is coated with an outside lipid-like layer, which protects the hair," says Dr. Jones. "As the hair grows out of the follicle, the cortex and cuticle become keratinized and harden." Dry or damaged hair is more susceptible to breakage. "The condition of the cuticle affects how the light reflects off the hair, giving it highlights and luster," Dr. Jones says. "Luster is affected both by what occurs inside the body as the hair is developing and what happens to the hair after it has grown from the shaft."

Sun, heat, moisture, pollution and hair products, dyes and bleaches can all dull the hair. "Applying chemical solutions to the hair, color, permanent waves or curl relaxers, damage the protein molecules that wrap around the shaft, leaving hair brittle and dull," says Christina Pirello, author of Glow: A Prescription for Radiant Health and Beauty (HP Books).

Conditioners and oils can leave a residue or weigh hair down. Hair sprays and products that contain alcohol can dry and damage the hair, as can using blow dryers and curling irons.

Hair's Natural Nutrients

To combat hair-raising havoc, feed your hair natural nutrients for health. Silica and plants that contain silica/silicon both strengthen hair and promote growth. "Silica is a good mineral for hair health," says Walter Siegordner, founder of The Aurora Group, a personal care company. "It helps in the keratinization process of the cells that produce hair."

" Silica is a mineral that is involved in the synthesis of bone and connective tissue," adds Dr. Jones. "The hair follicle contains connective tissue so silica may promote the health and function of the follicle itself." Silica-containing herbs include nettles (Urtica dioica), horsetail (Equisetum arvense), oatstraw (Avena sativa) and alfalfa (Medicago sativa).

Sea plants like seaweed and kelp also provide vital nutrients. "Sea plants are essential ingredients in many natural shampoos and can be used to fortify damaged hair," says Pirello. "They're rich in vitamin A that prevents the build-up of dead skin cells, which can clog the hair follicles, inhibiting the growth and health of the hair, and also contain vitamin B, linked to the prevention of oily hair, baldness and dandruff. Calcium found in sea plants is essential to the structure of the hair shaft."

Eaten on s daily basis, sea plants are rich in nutrients that help maintain healthy, shiny hair, free of split ends, Pirello says. Try wakame in soups and salads, kombu or kelp in bean and vegetable dishes, nori in sushi, and hiziki and arame as side dishes. Since hair health is affected by digestive health, the fiber found in whole grains also helps. "Fiber prevents accumulation in the intestines that can result in the formation of toxins," says Pirello.

Miso, she adds, is especially good hair food. It "is rich in living enzymes that ease digestion, fortify the quality of the blood nourishing the body and hair, and provide us with essential oils, vitamins and minerals."

Key nutritional support includes adequate protein and amino acids, essential fatty acids such as cold-pressed flax seed oil and fish oil, copper, vitamin A, vitamin E, vitamin D, biotin, iron and vitamin B5 (pantothenic acid). Zinc and selenium can help combat the effects of hyperthyroidism, which can result in thinning, lackluster hair.

Vitamin C can boost adrenal health. "When the adrenals are overtaxed and become fatigued, hair follicles will go into a resting phase," says Dr. Jones. (If you have a medical condition, she adds, check with your health care practitioner first before taking supplements.)

Ancient Chinese Hair Secrets

In Traditional Chinese Medicine, hair is associated with the kidneys' qi, energy that originates in these organs, and with blood quality. " From the traditional Chinese perspective, excess amounts of fat, protein, dairy, sugar, alcohol and salt in the diet acidify the body, damage the Kidney qi and are not good for the hair," says Dr. Jones. A diet rich in vegetables and grains is a great way to support healthy hair. "Iron and mineral-rich foods are considered blood builders and hair tonics. Foods such as blackstrap molasses, seaweed, nettles, and the herb polygonum multiflorum (also known as He Shou Wu and Fo-Ti) have been used throughout the years. Fo-Ti has also been used to prevent graying of the hair and support the immune system."

Revive Hair Glow

" Hair is extremely strong but at the same time it's extremely delicate," says Barsoum Bouchar, a cosmetologist and owner of the Virtuoso Salon in Birmingham, Michigan. "Many products work against the hair texture, so the cuticle is always raised. This causes tangles and split ends. With blow dryers, chemicals, colors and styling elements, the hair is tremendously abused." If you don't have to chemically treat the hair, he says, don't.

When replenishing the hair it's important to remember that it's composed of 97% protein and 3% moisture, says Bouchar. Shampoo cleanses the hair and removes buildup. "A moisturizer brings moisture back into the hair and smoothes the cuticle down, which is what makes hair shiny and gives it bounce. The one key ingredient in both shampoo and moisturizers is aloe vera. It heals the hair." " Avoid products with harsh surfactants like sodium laurel sulfate and propylene glycol," warns Siegordner. "These decrease the circulation in the scalp, reducing the pathway for nutrition to the hair bulb." Conditioners that aren't natural can also cause build-up. "When you apply heat to the hair through blow drying or styling, you end up 'burning' the hair," says Bouchar.

To stimulate hair growth, add a few drops of essential oils of rosemary, lavender and thyme to jojoba and almond oils, and rub into the scalp. Leave it overnight and then rinse it off. " Essential oils have antimicrobial and antifungal properties, stimulate the circulation to the hair follicles and combat dryness. They also smell good," says Dr. Jones.

For hair that's not chemically treated, "a vinegar rinse cleanses the hair, removes build-up and boosts shine," says Bouchar. Use one part vinegar to ten parts water, apply after a shampoo, comb though and rinse it off. To naturally lighten the hair, use the same ratio in a lemon rinse for five minutes for, say, four days in a row, and then stop.

If you want to color your hair, choose natural elements, too. "The best natural dye is henna," says Bouchar. "It's organic, just like hair is." Blonde hair becomes warmer with a coppery tone, brunette hair takes on a mahogany hue, gray hair looks like highlights.

Go Natural

To find a good natural hair stylist, Bouchar suggests asking which products they use and why. If your hair is chemically treated, it's especially important to work with a stylist you trust for the best care.

Keep your eye on the big picture when it comes to hair health. "Be proactive and treat the body holistically," urges Dr. Jones. "Nourish the glands, the organs and the vessels that are responsible for getting the necessary nutrients to the hair follicle. Pay attention to the physical, emotional and mental aspects of health. Once hair is lost it may come back but it will likely be thinner than it was before. It's important to take care of what you have."

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Vitanet ®

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Date: June 13, 2005 07:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Say Goodbye to Headaches

Say Goodbye to Headaches by Susan Weiner Energy Times, December 8, 1999

What's in a name? A headache by any other name hurts just as much. But categorizing your headache can be as overwhelming as finding an obscure breakfast cereal at the supermarket. Medical folks pigeonhole headaches as tension headaches, allergy headaches, morning headaches and sinus headaches, plus the organic, migraine, cluster, trauma, TMJ, eyestrain, rebound, exertion, hormonal and muscle tension varieties. You may also suffer the self-induced hangover and toxicity headaches.

Americans are no strangers to self-medication, and as a society we battle these headaches by consuming nearly 80 billion tablets of aspirin each year, about 20 million aspirins a day, according to Burton Goldberg, co-author of An Alternative Medicine Definitive Guide to Headaches (Future Medicine Publishing). And while we drown ourselves in over-the-counter and powerful prescription products, our tolerance, just like a drug addict's, grows. So what begins as a twodose headache slowly evolves into three, four or five doses, until you realize that no dosage can make your headache go away.

Unless you're fond of medieval practices such as ritualistic healings and bloodletting, drugs seem the only answer to headache misery. But even modern medicine has been unable to solve headaches. Rather than a cure, medications provide only temporary relief, and even that isn't guaranteed. Additionally, over-reliance on medications can lead to chronic head pain. According to Goldberg, rebound headaches often result from the consumption and withdrawal of drugs.

Halt Your Headaches

Rather than strive to simply eliminate headache pain, why not identify the underlying cause and prevent the headache? Almost always, every type of headache results from a health or lifestyle-related activity. In an ideal world, the best approach would be to eliminate the tensions, stress, frustrations, anger, insufficient sleep, excessive drinking and poor diet that contribute to your headaches. For better or for worse, however, you can't always: a. quit your job; b. ask your spouse to leave; c. sit on the beach all day; or d. all of the above. But you can make appropriate lifestyle changes and learn to express suppressed feelings.

This approach, lifestyle modification, is a treatment program based on a Loma Linda University study, originally published in Medical Hypothesis and the Journal of Women's Health and Gender-Based Medicine and later explained in No More Headaches, No More Migraines: A Proven Approach to Preventing Headaches and Migraines by Zuzana Bic, DrPH and L. Francis Bic, PhD (Avery). The program, conducted on a group diagnosed with chronic migraines, dramatically decreased the frequency, intensity and duration of headaches in nine of 10 headache sufferers. Rather than demand radical life changes, the lifestyle modification program introduces gradual changes in three specific areas: nutrition, exercise and understanding stress. The study doesn't expect you to change your entire diet, join a gym and eliminate everything that triggers stress, but teaches techniques to make subtle lifestyle changes and reduce the impact of daily stress. These same techniques can also improve sleep patterns, a factor known to affect headaches. The lifestyle modification approach clarifies that while very few headaches directly result from existing acute conditions, recurring headaches often derive from a larger lifestyle factor. If these issues are ignored, the body's natural defense mechanisms may kick into overdrive and become exhausted, leaving you susceptible to other chronic diseases. By finding and eliminating the cause of your headaches, you may be saving yourself from other eventual illnesses.

Natural Alternatives

Willing to make some lifestyle changes and step away from medications? Try these remedies, courtesy of Nature's Pharmacy by Lynn Paige Walker, PharmD and Ellen Hodgson Brown, JD (Prentice-Hall).

For simple headaches, start with relaxation and neck stretches. Or try rubbing your forehead with peppermint oil, a natural antispasmodic and diuretic shown in German research to be as effective as acetaminophen in easing tension headaches.

Never underestimate the old-fashioned ice pack to the forehead as an effective treatment that works by constricting the swollen blood vessels that cause your head to ache. If the ice pack isn't enough, try putting your arms in icy water up to your elbows to constrict additional blood vessels. But if it's a sinus headache you're fighting, take the opposite approach and try hot compresses.

The herbal, and original, form of aspirin is white willow bark. Used by Chinese practitioners 2,500 years ago, it contains salicin, nearly the same pain reliever found in aspirin. Other herbal aspirins include meadowsweet tea, just as effective as aspirin with few side effects. For migraines, Walker and Brown recommend feverfew and magnesium supplements, which reduce nerve excitability and migraine susceptibility. In fact, individuals with frequent headaches have been found to have low brain and tissue magnesium, says Julian Whitaker, MD, author of Julian Whitaker's Guide to Natural Healing (Prima). For all headaches, Goldberg suggests essential fatty acid supplementation with evening primrose oil (EPO), which improves circulation, helps regulate inflammation and relieves pain.

The Curse of the Migraine

Migraines, a debilitating headache distinguished by a throbbing pain, may be humanity's oldest malady. The name is derived from the word the Greek physician Galen used to describe the disorder in 200 A.D. Six-thousand-year-old Sumerian writings refer to the ravages of migraines, and prehistoric skeletons bear testimony to a crude form of trephination-holes chiseled in skulls to allow the escape of pain-creating demons, according to Lifetime Encyclopedia of Natural Remedies by Myra Cameron (Parker Publishing).

In the common migraine, throbbing pain develops gradually from distended veins around the brain and may be accompanied by nausea, vomiting and sensitivity to light. These miseries can be preceded by 15 to 90 minutes of an "aura," which includes visual disturbances, distorted perception, hallucinations, flashes of light and temporary loss of sight or hearing. In fact, skeptical historians attribute some of the religious visions of the Middle Ages to the visual effects of migraine aura, according to Cameron.

Snacking on high fiber foods between three light meals each day helps stabilize blood sugar and prevent migraines. And while some doctors summarily attribute migraines to diet, other experts attribute at least half of all migraines to food sensitivities. The most common edible villains are aged cheeses, yeast breads, chocolate, cured meats, citrus fruits, eggs, fermented foods, wheat, milk, milk products, alcoholic drinks and food additives, including nitrates and MSG.

Suggested daily supplements for migraine-susceptible individuals include a multivitamin, one capsule of B complex to help maintain normal vascular control, 3,000 to 6,000 milligrams in Divided doses of vitamin C with bioflavonoids to assist the production of anti-stress hormones, and 500 to 1,000 milligrams of magnesium to reduce nerve excitability and pain. At the onset of a migraine, says Cameron, try homeopathic remedies, dilutions of natural substances from plants, minerals and animals. For throbbing pain, take natrum muriaticum according to package directions. Other homeopathic options to explore include iris versicolar, lac defloratum and sanguinaria.

Take Charge of Your Headaches

Headache management involves managing your life. Practice relaxation techniques to reduce stress. Calmly discuss your feelings. Take a leisurely stroll at lunch. Walk your dog, or a neighbor's dog, after dinner. Keep a food diary. Sit and stand tall. Skip the fast food tonight. Join a yoga class. Take vitamins and supplements. Get a two-hour massage. Turn the television off earlier and sleep in a little later.

Taking the time to care may take effort, but it will soon become second nature. Invest in yourself. It's your most precious possession.

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Vitanet ®

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Date: June 12, 2005 08:03 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Down with Blood Pressure

Down with Blood Pressure by Kim Erickson Energy Times, January 6, 2002

More than one of four Americans suffers from high blood pressure, also known as hypertension. This so-called silent killer is often the first step in developing long-term problems like heart disease and stroke. According to the American Heart Association, high blood pressure leads to about 45,000 deaths a year and contributes to another 210,000. Hypertension is more common in women beginning at age 50, particularly African-American women. And since high blood pressure rarely causes obvious physical distress, unless your health practitioner monitors your blood pressure on a regular basis, it's easy to miss. The famous study by the National Heart, Lung and Blood Institute (NHLBI), known as the Framingham Heart Study, found that half of all people who suffered a first heart attack and two-thirds of first-time stroke victims also had moderate to high blood pressure. What's more, left untreated, high blood pressure can also increase the risk of atherosclerosis (hardening of the arteries), aneurysms, loss of vision and kidney failure. Normal blood pressure is considered 120/80. When blood pressure reaches 140/90 or above on a consistent basis, you have high blood pressure. What do the numbers mean? The top number, systolic pressure, represents the peak pressure generated in your arteries when your heart beats. The bottom number, diastolic pressure, indicates the pressure when your heart is at rest between heartbeats. Among 95% of all people with high blood pressure, health practitioners can generally pinpoint no specific, single cause.

So Salty

For decades, the most common recommendation for people with high blood pressure was to eat less salt. Experts have advocated reducing our salt intake to no more than three teaspoons a day: six grams (2400 mg), which is four grams less than the current national average. This recommendation was largely based on a study conducted by Northwestern University Medical School in Chicago, Illinois, known as INTERSALT. The study tested more than 10,000 men and women from 32 countries. The researchers concluded that eating a lot of salt was linked to rises in blood pressure. Other scientists haven't always found the same results. One review of 56 clinical trials by the Integrative and Behavioral Cardiology Program at the Mount Sinai School of Medicine in New York found only a modest reduction in blood pressure when the salt shaker was left unshaken. And an analysis of 58 studies by academics at the University of Copenhagen, Denmark found that, overall, studies did not support a general recommendation to reduce the amount of salt we consume. Added to all this confusion, many people are salt sensitive: their bodies retain excess salt instead of flushing it out of their systems. Unfortunately, only medical tests can reveal this sensitivity. Consequently, experts still recommend that you eat fewer foods containing salt. That means going easy on processed foods, lunch meats and soft drinks. In addition, increasing your intake of potassium, calcium and magnesium may help your blood pressure.

Mitigating Minerals

Foods rich in potassium and magnesium not only help regulate blood pressure, but may boost overall cardiovascular health and reduce the risk of stroke. Vegetarian items such as bananas, baked potatoes and oranges are rich in these minerals. Research that looked at 30,000 doctors found that those who ate diets rich in fiber, potassium and magnesium had lower blood pressure than the men who ate few of these mineral-rich foods (Circ, 1992; vol 86:1475-1484). A study of 40,000 female nurses found that their pressure decreased when they consumed fibrous and magnesium-filled foods (Hypertension, 1996, vol 27:1065-1072).

CoQ10

The nutrient CoQ10 is a vitamin-like substance which acts as an antioxidant in the body, decreasing the harm caused by caustic substances known as free radicals. Found in every part of the body, CoQ10 is necessary for producing energy in every cell. But it is estimated that nearly 40% of people with high blood pressure are deficient in CoQ10. Tests of CoQ10 seem to show that it can often reduce blood pressure by almost 10% (Cur Ther Res 1990;47: 841-845). It also appears to reduce blood triglycerides, blood fats linked to heart disease, and insulin, while slightly increasing HDL (good) cholesterol.

Food Fight

Perhaps the biggest breakthrough in lowering blood pressure without the use of prescription medicine came with a study known as DASH (Dietary Approaches to Stop Hypertension). Funded by NHLBI and the National Institutes of Health, the multicenter study examined more than 400 people with high blood pressure. These folks were Divided into three groups. One ate the standard high-sodium, high-fat American diet, the second a diet high in fruits and vegetables, and the third a combination diet rich in fruits, vegetables and low-fat dairy products (the DASH diet). While the group eating plenty of fruits and vegetables enjoyed a modest reduction in blood pressure, the study found that combining low-fat dairy with produce lowered both systolic and diastolic blood pressure by 11.4 and 5.5 points, respectively. And the benefits came quickly. Many of the people on the combination diet lowered their blood pressure within two weeks. The results were so impressive that researchers at Brigham and Women's Hospital in Boston, Massachusetts suggested that the DASH diet may offer an alternative to drug therapy for people with hypertension and may even serve to prevent high blood pressure altogether. The DASH diet is low in saturated fat and rich in whole grains, fruits and vegetables. Similar to the diet found in Mediterranean cultures, DASH also includes nuts, seeds and legumes, and is supplemented by non- or low-fat dairy products. Moderate amounts of protein-in the form of fish, poultry and soy-are also eaten. Eating in the DASH may also spur weight loss. Since being overweight can increase your blood pressure, the NHLBI strongly recommends a low-calorie diet such as DASH to take off extra pounds. Exercise and stress relief play critical roles in most pressure-reducing plans. Working out not only helps shed weight, it can also lower your blood pressure. Low to moderate aerobic exercise four days a week may lower blood pressure just as effectively as a higher intensity workout. And learning how to manage stress has helped dropped pressures in people with hypertension (Arch Intern Med 2001; 161:1071-80). Nutrition and lifestyle: two vital relief valves for dropping your high blood pressure and increasing your chances of longer life.

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Vitanet ®

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Date: June 10, 2005 09:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nutrients for Longevity

Nutrients for Longevity by Edward C. Wallace, ND, DC Energy Times, September 1, 1999

What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful easy feeling.

How Do We Age

Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.

The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.

Programmed Cell Theory

In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.

Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.

Free Radical/Oxidative Stress Theory

The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain.

On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution.

Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.

DNA Repair Theory

Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.

What Can We Do

The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.

In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."

Antioxidant Protection

Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.

Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.)

Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.

In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725).

Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.

Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.

Nutrition Deficiencies

A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).

When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).

A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.

Longevity Diets

A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460)

Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers. (Epidemiology 3[5], 1992: 389-391).

Staying Alive

Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.

Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects. (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).

In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.

Longevity and Exercise:

Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.

Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184).

In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.

The Treadmill of Life

The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying. (JAMA 273 [14], April 12, 1995: 1093-1098).

Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.

Longevity Supplementation

Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging.

Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.

Toning Down Enzymes

Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls.

In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).

In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.

The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).

Vitamins E & C

A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.

Chronological Age Vs. Biological Age

Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.

Similar Relationship

A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers Divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.

The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).

Carotenoids

When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.

Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119(1), Jan. 1989: 112-115).

Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.

Flavonoids

Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs.

For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.

Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).

Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.

Amino Acid Health

Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68).

As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.

Attitude & Behavior

Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit.

In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).

In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).

Longevity at Last

While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of living longer. An added benefit: By staying healthier, your old age won't only be longer, it will be more enjoyable, too.

And, who knows, if you hang around long enough, taking your nutrients and getting a comfortable amount of consistent exercise, while meditating and refusing to succumb to stress, that magic bullet that will keep you alive for centuries may be discovered. Some day a new antioxidant or other substance may finally prove to provide the elusive fountain of youth. Stay tuned.

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