Serving Size:

4 tablets contain:
Vitamin C (as ascorbic acid) 600 mg
Vitamin E 16 IU
(from gamma-vitamin E complex)
Niacin (as inositol hexanicotinate) 500 mg
Iodine (from kelp) 150 mcg
Selenium (as L-selenomethionine [SelenoPure™] & sodium selenite) 100 mcg
Chromium (as chromium polynicotinate [ChromeMate®] & chromium picolinate) 100 mcg
Phytosterol Complex 40% 750 mg
Yielding 300 mg beta-sitosterol
Garlic Powder Extract 600 mg
(standardized to 8,000 ppm allicin)
Turmeric Extract 526 mg
Yielding 500 mg curcumin
gamma-Vitamin E Complex 500 mg
Inositol 350 mg
(as inositol and inositol hexanicotinate)
Red Yeast Rice 350 mg
Yielding 1.5% mevinolinic acid monacolins
Artichoke Extract 250 mg
(standardized to 2.5% cynarins)
L-Arginine (as L-arginine HCl) 240 mg
Methylmethioninesulfonium Chloride 200 mg
(vitamin U)
Green Tea Extract 105 mg
Yielding 100 mg polyphenols, 36 mg EGCG
Sytrinol™ 100 mg
(proprietary blend of citrus polymethoxylated
flavones and palm tocotrienols)
Soy Bean Concentrate 100 mg
Yielding 40 mg total isoflavones
Ginkgo Leaf 24% (50:1 Extract) 60 mg
Guggul Extract (10% guggulsterones) 50 mg
Dandelion Root Extract (4:1) 50 mg
Hawthorne Berry Extract (4:1) 50 mg
Myricetin 30 mg
Policosanol 10 mg
Coenzyme Q10 5 mg

Suggested Use: Take 4 tablets each night or as recommended by your health care professional.

We offer Source Naturals at 46% OFF Man. Suggested Retail

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Vitanet ®

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Date: July 01, 2005 04:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Immune Health - Herbs to Maintain A Healthy Immune System

Immune Health By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt The immune system has been receiving a lot of media attention, especially since the rise in recognized immune system deficiency diseases. The efficient functioning of the immune system is of paramount importance to everyone, adults and children alike, since it controls our ability to fend off illness, whether it is a common cold or more deadly disease. The immune system is made up of a combination of specialized cells, chemicals, tissues and organs. These include the lymph nodes, thymus gland, spleen, bone marrow and tonsils, as well as specialized white blood cells, which recognize and engulf invading microorganisms and cellular debris.

The ability of the immune system to function optimally is influenced by many factors. These include inherent genetic makeup, environmental influences (such as pollution, pesticides, hormones, artificial flavoring/colorings in food), obesity, stress levels, exposure to infective agents, etc. Specific research suggests that consuming excessive amounts of sugar interferes with immune function. We can aid our immune system by eating a high amount of organic green vegetables, whole grains and nuts, while cutting down on 'junk food' consumption. Stress reduction, through prayer, meditation, yoga and moderate exercise can also help.

Herbs may be used in two different ways to help the immune system. Tonics strengthen the immune system over time, while strong immune system stimulants have a more immediate action, and are used during an acute infection.

Tonics

Herbal tonics work to help maintain a dynamic balance in the body and usually need to be taken long-term. Astragalus is said to build "Wei chi". "Chi" is the Chinese concept of life energy force. "Wei chi" is thought of as 'protection'. Current scientific studies confirm the positive benefits of Astragalus on the immune system. One study by the National Cancer Institute demonstrated Astragalus' ability to help strengthen resistance of the immune system, especially to viral infections. Reishi, called the "mushroom of immortality", has been used for centuries as an overall tonic. Chinese physicians have used Ligustrum berries specifically for their immune-enhancing activities. They are often combined with Astragalus for a synergistic effect. Coptis is another Chinese herb that contains the bitter yellow compound, berberine. This herb helps the immune system prevent infections. Many of these herbs can be found in the unique combination formula called Immunotonic™ (alcohol-free). Immunotonic™ offers the ideal way to experience the benefits of many herbs in one convenient supplement.

Other immune system tonic herbs include Siberian Ginseng and Schisandra. Siberian Ginseng is an adaptogen that helps to balance the immune system. It gives strength and fortitude, especially when dealing with environmental stress. Schisandra has been shown to build non-specific resistance, improve brain function, increase work capacity and build strength.

Immune Stimulants

Osha Root has been used traditionally by both Chinese and Native Americans (who called it Chuchupate) for colds and flues, sore throats and other health ailments requiring a higher level of immune support. Echinacea is a well-researched and respected immune system stimulant. (Refer to our Echinacea article for further information). It helps increase the activity of white blood cells, which engulf invading microorganisms. Thuja is an herbal extract from the Northern White Cedar tree. It is a strong immune stimulant that Native Americans used for colds, coughs, bronchitis and other respiratory infections. Possibly the mushroom with the greatest capability of stimulating the immune system is the Maitake. It is known as the "dancing mushroom" because it was so highly prized that whoever found some would dance for joy. Maitake contains specific chemical components that have been scientifically studied for their strong immune enhancing effects; (refer to Maitake Bio-Beta-Glucan™ article for further information). Nature's Answer® combines these herbs in Immune Boost™, a combination formula for use during acute illness and infections. Try it along with the combination formula Echinacea & Goldenseal. Nature’s Answer® offers a selection of all these herbs in liquid and/or capsule forms. Check with your local health food store, or visit www.naturesanswer.com, for more information.

For Kids

Children can often use a boost to their immune system to help ward off colds and flues. Nature's Answer® comes to the RESCUE with three alcohol-free formulas specifically designed for their special needs - E-KID-nacea™, E-KID-nacea Plus™, and NatChoo™. All of these outstanding formulas help promote a healthy immune system.

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Vitanet ®

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Date: June 29, 2005 01:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CHOLESTEROL RESCUE - Maintain Your Cholesterol Wellness

CHOLESTEROL RESCUE

You live in a fat-drenched, fast food world, propped up by diets loaded with processed foods that stimulate your body to create excess bad cholesterol – or low-density lipoproteins (LDL). Your busy life is full of stress, and devoid of time for proper exercise. There are three ways to deal with cholesterol in the body, but a seemingly infinite number of lifestyle and hereditary elements that affect LDL levels. Is it any wonder you find yourself in danger of developing unwanted cholesterol levels? Source Naturals is devoted to helping you. So we developed CHOLESTEROL RESCUE as a comprehensive solution to help you keep cholesterol levels in the normal range. CHOLESTEROL RESCUE uses only natural ingredients, clinically researched to effectively maintain healthy cholesterol levels. It is scientifically formulated with the triple action of three ingredients that target the ways you can deal with your cholesterol concerns; combining the naturally occurring polymethoxylated flavone (PMF) and tocotrienol action of Sytrinol™ with the action of plant sterols. Research suggests that daily consumption of 800 mg of plant sterols, taken with food in two divided doses as part of a diet low in saturated fat and cholesterol, may reduce the risk of coronary heart disease. Source Naturals offers CHOLESTEROL RESCUE as part of our ongoing commitment to providing you with high quality natural supplements to support your healthy lifestyle.

Cholesterol & Your Body

On average, humans ingest approximately 300mg of cholesterol per day. Though an important part of a healthy body, a high level of cholesterol in the blood might be out of the normal range. Cholesterol is transported in your system by lipoproteins. There are two kinds of lipoproteins in your body, but the low-density lipoproteins, or LDL, are the major factors in developing unwanted cholesterol levels. If there are high levels of LDL circulating in your bloodstream, it can undergo oxidation by free radicals in the artery walls, which can then become trapped as imbalanced deposits. These deposits can build up, reducing critical blood-flow. CHOLESTEROL RESCUE has been specially developed to reduce LDL levels using two different methods: inhibiting the synthesis of cholesterol in the liver, and reducing the absorption of dietary cholesterol.

The Plant Sterol Effect

Sterols are an essential component of the cell membrane, and are produced by both plants and humans. While the most common sterol produced in humans is cholesterol, plants produce phytosterols, or plant sterols. Using a complex compound of plant sterols similar to cholesterol with only slight molecular differences, CHOLESTEROL RESCUE has been formulated to balance the amount of dietary cholesterol your body absorbs.

Plant sterols have long been known to inhibit the uptake of both dietary and bile-produced cholesterol in the intestines. The most plausible theory behind this is that, because of the similarity between plant sterols and cholesterol, the body cannot properly distinguish between the two during the absorption process, thereby displacing the uptake of cholesterol into your system. Research suggests that daily consumption of 800mg of plant sterols, taken with food in two divided doses as part of a diet low in saturated fat and cholesterol, may reduce the risk of coronary heart disease.

Sytrinol™ For Heart Health

CHOLESTEROL RESCUE also contains SYTRINOL™, a proven natural alternative for maintaining cholesterol wellness. The patented blend of citrus polymethoxylated flavones (PMFs) and tocotrienols has been clinically shown to promote cardiovascular health by supporting normal cholesterol production by your liver, helping balance triglyceride production, and providing powerful antioxidant protection. The PMFs promote normal cholesterol levels by inhibiting both the production of cholesterol precursors, such as cholesteryl esters, and the activity of HMG CoA Reductase, an enzyme that synthesizes cholesterol in the liver. These PMFs can also balance the body’s production of triglycerides by inhibiting your liver’s triglyceride producing enzyme, diacylglycerol acetyltransferase. Tocotrienols help break down cholesterol building blocks, interfere with cholesterol production, and provide critical antioxidant protection. Because cholesterol becomes problematic when oxidized, the powerful antioxidant action of tocotrienols can help prevent the conditions that may affect your cardiovascular circulation.

Spearheading the Wellness Revolution in Cholesterol Defense

With so many ways to develop undesirable cholesterol levels in your body, you need to be proactive in maintaining your good health. In our on-going dedication to your wellness, and a commitment to delivering the benefits of our high quality supplements to the natural products marketplace, Source Naturals has produced a scientifically formulated blend of three effective ingredients in fighting unwanted cholesterol. Combining a comprehensive formula of allnatural components, clinically researched for promoting cardiovascular health, CHOLESTEROL RESCUE is available now at your local health food store.

References
Guthrie N, Kurowska EM. Anticancer and Cholesterol-lowering activities of citrus flavonoids. Handbook of Nutraceuticals and Functional Foods. (Wildman, R.E.C., ed), CRC Press, Boca Raton, FL. 2001. 113-126. Packer L, Weber SU, Rimbach G. Molecular aspects of alphatocotrienol antioxidant action on cell signaling. Symposium: Molecular Mechanisms of Protective Effects of Vitamin E in Atherosclerosis. American Society for Nutritional Sciences. 2001. 131:369S-373S. Hicks KB, Moreau RA. Phytosterols and phytostanols: functional food cholesterol busters. Food Technology. 2001. 55:63-67. Middleton Jr E, Kandaswami C, Theoharides TC. The effect of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacological Review. 2000. 52:673-751. Child P, Kuksis A. Critical role of ring structure in the differential uptake of cholesterol and plant sterols by membrane preparations in vitro. Journal of Lipid Research. 1983. 24: 1196-1209

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Vitanet ®

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Date: June 29, 2005 09:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...

SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...

Maintaining your cardiovascular health is one of the best ways you can stay fit. That means working to keep your cholesterol levels within the normal range. And contrary to popular belief, the amount of cholesterol you consume in food is not the most important factor for regulating normal cholesterol levels. It is actually the liver’s imbalanced production of cholesterol that is much more critical for your cardiovascular health.

You can address the root cause of maintaining normal cholesterol levels today with Source Naturals SYTRINOL™. This patented blend of citrus polymethoxylated flavones and tocotrienols has been clinically shown to promote cardiovascular health by supporting normal cholesterol production by your liver, promoting balanced triglyceride (fat) production, and providing antioxidant protection. Source Naturals, an industry leader in many categories, introduces the science of SYTRINOL™ in the CHOLESTEROL RESCUE™ product family to support your better heart health today.

The Truth About Cholesterol

Cholesterol is a very confusing subject – our bodies require it but we can also get too much of it. Cholesterol is one type of the ring-shaped compounds called sterols. Other sterols include bile acids, sex hormones, adrenal hormones and vitamin D. Approximately 90% of the cholesterol in your body is in your cell membranes. The remaining 10% can be found in your blood and throughout your body.

Liver’s Over-Production of Cholesterol

When your body needs more cholesterol, your liver takes carbohydrates, proteins and fats (also called triglycerides) from your diet and converts them into cholesterol. The amount of cholesterol that you might consume from foods (in animal products such as eggs, milk, cheese and beef ) is minute compared to the amount of cholesterol produced by your liver. Thus, cholesterol from food isn’t as critical to your total cholesterol. But balancing the cholesterol produced by your liver is very critical to your total cholesterol and thus, your cardiovascular health.

Oxidized LDL Cholesterol

Despite the confusion, cholesterol is a vital component of good health that strengthens cell membranes and provides building blocks for hormones, bile and vitamin D production. However, there is one potential pathway where cholesterol can contribute to an imbalance. When cholesterol moves through the blood to individual cells, it can travel in groups such as lipoproteins, which also contain fats and proteins. When the cholesterol is moving through your blood in Low Density Lipoproteins (LDL) it can undergo oxidation by free radicals in the artery walls. Some medical experts theorize that the oxidized LDL cholesterol becomes trapped in the artery walls as imbalanced deposits instead of completing the journey to join cell membranes. These deposits can eventually reduce the size and function of the arteries, compromising blood flow. Thus, antioxidant protection, balanced triglyceride production, and normal cholesterol production by the liver can all be critically important to your good health. And SYTRINOL™ provides all of these benefits.

How SYTRINOL™ Supports Heart Health

SYTRINOL is a powerful scientifically formulated blend protected by U.S. patent numbers 6,251,400, 09/ 481724. It contains natural citrus polymethoxylated flavones (PMFs) and tocotrienols that go deep to address the root causes of cholesterol wellness.

Citrus PMFs

Polymethoxylated flavones are types of polyphenolic compounds called flavonoids, which are the largest known category of phytonutrients. Health benefits of various flavonoids include antioxidant activity, immune system support, and cellular protection. The unique structure of polymethoxylated flavones, which naturally contain methyl groups paired with oxygen in key places, enables PMFs to interfere with cholesterol production. The citrus PMFs in SYTRINOL, such as tangeretin and sinensetin, promote normal cholesterol levels by inhibiting both the production of cholesterol precursors, such as cholesteryl esters, and the activity of HMG CoA Reductase, an enzyme that synthesizes cholesterol in the liver. These PMFs can also balance the body’s production of triglycerides by inhibiting the activity of your liver’s triglyceride producing enzyme, diacylglycerol acetyltransferase. Since LDL cholesterol is made from cholesterol and triglycerides, decreasing your liver’s production of triglycerides will reduce the amount of those triglycerides available to form LDL cholesterol compounds.

Tocotrienols

Tocotrienols are compounds similar to vitamin E in structure and function. The tocotrienols in SYTRINOL increase degradation of cholesterol building blocks such as Apolipoprotein B, interfere with cholesterol production, and provide antioxidant protection. The tocotrienols in SYTRINOL are also especially protective antioxidants for LDL cholesterol compounds that have already been produced, helping to prevent the oxidized LDL cholesterol conditions that may affect your cardiovascular circulation.

SYTRINOL’s Proactive Synergy

SYTRINOL works so well because this natural blend of PMFs and tocotrienols works proactively, synergistically, and independently. In preliminary human research, SYTRINOL proactively supported balanced cholesterol and triglyceride production by the liver through the synergistic effects of the PMFs and tocotrienols. Furthermore, SYTRINOL promotes LDL cholesterol antioxidant protection.

The above information has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Other products work reactively to disable existing cholesterol and may only work in conjunction with diets. And because SYTRINOL works independently of diet, you can take it anytime.

Three Lifestyle Strategies for Cardiovascular Health

1. Exercise regularly to increase hearthealthy HDL cholesterol and lower blood triglycerides (fats).

2. Eat a healthy diet rich in fruits, vegetables, whole grains, and lean proteins to help maintain normal cholesterol and triglyceride levels.

3. Take the right supplements to promote your cardiovascular health. In preliminary clinical studies, the amino acid L-ARGININE supported healthy blood flow to the heart and body. GARLIC OIL helps to maintain healthy cholesterol levels and promotes healthy circulation. POLICOSANOL CHOLESTEROL COMPLEX, CHOLESRESPONSE™, CHOLESFIBER™, CHOLESTREX®, and GRAPEFRUIT PECTIN all help to support normal cholesterol levels. HEART RESPONSE™ and HEART SCIENCE™ are advanced formulas that address heart health. Additionally, you can get cardiovascular system supporting compounds such as folic acid, betacarotene, CoQ10, lipoic acid, ginkgo, grapeseed extract, hawthorn extract, magnesium, vitamin E, and many other nutrients in LIFE FORCE MULTIPLE™, Source Naturals’ best-selling multiple. There is a revolution underway in natural health consciousness, and your local health food store is at the forefront. You can benefit right now – long before word spreads to the general public – with the innovative heart nutrition of SYTRINOL, a CHOLESTEROL RESCUE™ product. SYTRINOL™ is a trademark of KGK Synergize exclusively licensed worldwide to SourceOne Global Partners.

References
Guthrie, N. and Kurowska, E.M. (2000). Anticancer and Cholesterol-Lowering Activities of Citrus Flavonoids. Handbook of Nutraceuticals and Functional Foods, Wildman, R.E.C, Ed., CRC Press, Boca Raton, FL, 113-126. Guthrie, N. and Kurowska, E.M. (2000). Anticancer and Cholesterol-Lowering Activities of Tocotrienols. Handbook of Nutraceuticals and Functional Foods, Wildman, R.E.C, Ed., CRC Press, Boca Raton, FL, 269-280.

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Vitanet ®

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Date: June 17, 2005 10:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: *New -- Policosanol 20MG - from Source Naturals

NEW PRODUCT ANNOUNCEMENT Policosanol 20 mg

Supports Cardiovascular Health!

1 tablet contains:
Policosanol (from sugar cane) 20 mg

Suggested Use: 1 tablet daily in the evening. Source Naturals recommends that a minimum of 30 mg of CoQ10 be taken per 20 mg tablet of policosanol. Some research suggests that CoQ10 levels in the body may be lowered by compounds that work on the same metabolic pathway as policosanol.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=371)

Date: June 14, 2005 05:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Catch Your Breath

Catch Your Breath

by Carl Lowe Energy Times, October 10, 2004

Asthma is on the rise. This serious breathing problem already afflicts 300 million people around the world and is expected to hinder the lung function of 400 million people in 20 years (Annual World Asthma Meeting, 2/17/04).

In the US, asthma continues to strike our kids. According to the US Environmental Protection Agency (2/24/03), the rate at which kids developed asthma doubled between 1980 and 1995. By 2001, 6.3 million American kids had asthma. The cost of treating all these kids: more than $3 billion a year.

Few researchers are prepared to state definitively why asthma rates have continued to climb during the past two decades. However, many investigators point to factors that seem inextricably linked to this disorder, which is marked by wheezing, shortness of breath and coughing spells.

CO2 Buildup

A report from the American Public Health Association and researchers at Harvard puts a lot of the blame for the high rate of asthma on global warming, smog and the atmosphere's growing burden of carbon dioxide. These are linked to industries and car exhaust that release pollution.

In this increasing burden of toxins released into the atmosphere, the rate of asthma among toddlers has grown to be particularly worrisome. Their rate of asthma has climbed more than twice the national average: by 160% between 1980 and 1994. According to these researchers (Inside the Greenhouse: The Impacts of CO2 (Carbon Dioxide) and Climate Change on Public Health in the Inner City), global warming-which involves large increases in atmospheric carbon dioxide released by internal combustion engines and and industrial processes-has fomented the asthma epidemic in several ways:

• Extra heat in the atmosphere has stimulated rapid plant growth that results in more fungus, pollen and spores; this causes allergies that often lead to asthma. Weeds like ragweed, which release allergenic particles, have greatly increased during the past few years. • Extreme weather has caused more floods and damp houses, leading to more indoor air pollution from molds. • Diesel pollutants are now combining with pollen and mold to irritate lungs, causing troublesome allergic reactions.

Bus Fume Hazards

The report notes that in neighborhoods like Harlem, in New York City, 25% of all children suffer asthma. Rates are particularly high in children who live in apartments that are located along bus routes.

A finding that surprised the scientists is the fact that carbon dioxide released by city traffic and the burning of coal and natural gas persists over urban areas, causing a dome of CO2 pollution.

Research on air quality in New York City, Phoenix and Baltimore shows that these lingering CO2 domes contain from 400 parts per million (ppm) of carbon dioxide to 600 ppm. Those levels are significantly above the global average of 379 ppm. Over the course of the earth's history, going back more than 400,000 years before the Industrial Age, research shows the atmosphere has averaged only 180 to 280 ppm.

Nighttime Distress

Breathing difficulties that increase at night can point to asthma, according to Robert Fink, MD: "Asthma can be a nocturnal disease, at its worst between 10 pm and 4 am, when cortisol [a hormone that regulates many bodily functions] levels are lowest" (Pediatric Asthma: Diagnosis and Treatment Goals, Medscape).

Dr. Fink says that if problems with breathing are bad enough to interfere with sleep, a health practitioner should be consulted to analyze the difficulty.

Diet and Asthma

Although nobody can guarantee protection against asthma, research suggests that eating plenty of fruits and vegetables can significantly reduce your risk. For instance, a study in Australia found that people who ate the most apples and pears reduced their chances of suffering from this breath-robbing disorder.

In research involving about 1,600 people, aged 20 to 44, they found that those who consumed the largest quantity of these fruits enjoyed the lowest rate of asthma (AJCN 2003; 78:414).

This is the latest study to confirm the fact that apples and other fruits help to keep lungs healthy. " There is extensive evidence from studies over the last 10 to 15 years that a diet rich in fruits and vegetables is beneficial to lung health," observes Carol Trenga, PhD, a research scientist at the University of Washington in Seattle. "The most compelling evidence is linked to fruits high in vitamin C, which are associated with improved lung function in the general population of adults and children."

Produce for Smokers

Quitting smoking represents one of the best ways to reduce lung disease. But even if you smoke, research on smokers has found that those who ate a moderate amount of fruits and vegetables have fewer lung problems (American Thoracic Society 97th International Conference 5/2001).

And you don't have to change your diet very much to make a difference: In that research, merely eating one and half pieces of fruit a day or eating about a tablespoon of vegetables daily significantly dropped smokers' chances of serious lung disease.

Fruits and Veggies to the RESCUE

In a study at the University of Nottingham, United Kingdom, scientists looking at the diets of more than 2,500 people found that eating five or more apples or three tomatoes a week increased lung function. Eating apples and tomatoes also reduced the risk of wheezing.

" The likelihood is that any effect is due to the concerted action of all the nutrients in apples and tomatoes, especially the antioxidants that are particularly rich in the peel of apples and contribute to the coloring of tomatoes," says researcher Sarah Lewis, PhD.

" Antioxidants may work by protecting the airways against the insult of tobacco smoke and other atmospheric pollutants," she adds. Dr. Trenga recommends that everyone eat at least five servings of fruits and vegetables a day. She also notes, "[I]t is reasonable to suggest modest supplementation with for example, vitamin C (250-500 mg twice/day) and vitamin E (up to 400 IU per day), in at-risk populations as a complementary therapy after considering the specific needs of the individual...These levels are very safe and have other health benefits (such as vitamin E and heart disease) in addition to potentially improving lung health."

Herbal Relief

Since asthma is linked to allergies, herbs that help to quell respiratory allergies can possibly lower your risk of asthma. A blend of standardized herbal extracts that contains Phyllanthus emblica (Indian gooseberry or amla), Terminalia chebula (Harda or Haritaki), Terminalia bellerica (bedda nut tree), Albizia lebbeck (Indian walnut), Zingiber officinale (ginger root), Piper longum (Indian long pepper), and Piper nigrum (black pepper) has been found to improve breathing and reduce the effect of allergies (FASEB J 2004; Vol II:A912, Abs. 600.8). Other studies have shown that these herbs can relieve nasal congestion, ease sneezing and clear bothersome mucus (J Am Coll Nutr 22(5): Abs 46, 2003).

Antibiotic Avoidance

Avoiding antibiotics may also lower the risk of asthma. " Over the past four decades there has been an explosive increase in allergy and asthma in westernized countries, says Mairi Noverr, PhD, a researcher who has looked at the lin between antibiotic use with asthma and allergies. " We propose that the link between antibiotic use and dysregulated pulmonary immunity is through antibiotic-induced long term alterations in the bacterial and fungal GI microflora."

In other words, Dr. Noverr's research shows that beneficial bacteria in people's intestines, which take part in strengthening immunity and regulating the immune response to pollen, may have been harmed by the overprescription of antibiotics by physicians. Dr. Noverr and his fellow researchers gave lab animals antibiotics before exposing them to candida albicans (a yeast infection). They then exposed the animals to mold spores. The result: a greater sensitivity to inhaling the spores and breathing problems similar to what people experience during hay fever season (104th General Meeting American Society of Microbiology).

" The studies presented here are the first direct demonstration that antibiotic therapy can promote the development of an allergic airway response," says Dr. Noverr. On a global scale, the outlook for asthma is worrisome. As other countries continue their industrial growth, the burden on the earth's atmosphere will grow. Meanwhile, few serious measures are being taken to reduce global warming, and the national diet frequently neglects lung-friendly vegetables and fruits. But within that uncertain scenario, you can boost your chances of healthy lungs: Eat more apples. Stay away from smoky buses. Hope for clear skies.

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Vitanet ®

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Date: June 13, 2005 03:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Menopause: Disease or Condition?

Menopause: Disease or Condition?

by Mary Ann Mayo & Joseph L. Mayo, MD Energy Times, September 4, 1999

It's front-page news. It's politically correct and socially acceptable. Talking about menopause is in. Suddenly it's cool to have hot flashes. Millions of women turning 50 in the next few years have catapulted the subject of menopause into high-definition prominence.

It's about time. Rarely discussed openly by women (what did your mother ever advise you?), meno-pause until recently was dismissed as "a shutting down experience characterized by hot flashes and the end of periods." Disparaging and depressing words like shrivel, atrophy, mood swings and melancholia peppered the scant scientific menopausal literature.

What a difference a few years and a very vocal, informed and assertive group of Baby Boomers make. Staggered by the burgeoning numbers of newly confrontational women who will not accept a scribbled prescription and a pat on the head as adequate treatment, health practitioners and researchers have been challenged to unravel, explain and deal with the challenges of menopause.

Not An Overnight Sensation

Menopause, researchers have discovered, is no simple, clear cut event in a woman's life. The "change of life" does not occur overnight. A woman's body may begin the transition toward menopause in her early 40s, even though her last period typically occurs around age 51. This evolutionary time before the final egg is released is called the perimenopause. Erratic monthly hormone levels produce unexpected and sometimes annoying sensations.

Even as their bodies adjust to lower levels of estrogen, progesterone and testosterone, some women don't experience typical signs of menopause until after the final period. A fortunate one-third have few or no discomforts.

Hormonal Events

According to What Your Doctor May Not Tell You About Premenopause (Warner Books) by John R. Lee, MD, Jesse Hanley, MD, and Virginia Hopkins, "The steroid hormones are intimately related to each other, each one being made from another or turned back into another depending on the needs of the body...But the hormones themselves are just part of the picture. It takes very specific combinations of vitamins, minerals and enzymes to cause the transformation of one hormone into another and then help the cell carry out the hormone's message. If you are deficient in one of the important hormone-transforming substances such as vitamin B6 or magnesium, for example, that too can throw your hormones out of balance. Thyroid and insulin problems, toxins, bad food and environmental factors, medication and liver function affect nutrient and hormone balance."

The most important reproductive hormones include:

Estrogen: the female hormone produced by the ovaries from puberty through menopause to regulate the menstrual cycle and prepare the uterus for pregnancy. Manufacture drops significantly during menopause. Estradiol is a chemically active and efficient form of estrogen that binds to many tissues including the uterus, breasts, ovaries, brain and heart through specific estrogen receptors that allow it to enter those cells, stimulating many chemical reactions. Estriol and estrone are additional forms of estrogen.

Progesterone: also produced by the ovaries, it causes tissues to grow and thicken, particularly during pregnancy, when it protects and nurtures the fetus. Secretion ceases during menopause.

Testosterone: Women produce about one-twentieth of what men do, but require it to support sex drive. About half of all women quit secreting testosterone during menopause.

Estrogen's Wide Reach

Since estrogen alone influences more than 400 actions on the body, chiefly stimulating cell growth, the effects of its fluctuations can be far-reaching and extremely varied: hot (and cold) flashes, erratic periods, dry skin (including the vaginal area), unpredictable moods, fuzzy thinking, forgetfulness, fatigue, low libido, insomnia and joint and muscle pain.

Young women may experience premature menopause, which can occur gradually, as a matter of course, or abruptly with hysterectomy (even when the ovaries remain) or as a result of chemotherapy. Under such conditions symptoms can be severe.

In the 1940s doctors reasoned that if most discomforts were caused by diminishing estrogen (its interactive role with progesterone and testosterone were underestimated), replacing it would provide relief. When unchecked estrogen use resulted in high rates of uterine cancer, physicians quickly began adding progesterone to their estrogen regimens and the problem appeared solved.

For the average woman, however, hormone replacement therapy (HRT) became suspect and controversial, especially when a link appeared between extended use of HRT (from five to 10 years) and an increase in breast and endometrial cancers (Journal of Clinical Pharmacology 37, 1997). The result: Women have drawn a line in the sand between themselves and their doctors.

Resolving The Impasse

Since hormone replacement reduces the risk of major maladies like heart disease, osteoporosis, Alzheimer's, colon cancer and diabetes that would otherwise significantly rise as reproductive hormone levels decrease, most doctors recommend hormone replacement shortly before or as soon as periods stop. Hormone replacement also alleviates the discomforts of menopause.

But only half of all women fill their HRT prescriptions and, of those who do, half quit within a year. Some are simply indifferent to their heightened medical risks. Some are indeed aware but remain unconvinced of the safety of HRT. Others complain of side effects such as bloating, headaches or drowsiness.

Women's resistance to wholesale HRT has challenged researchers to provide more secure protection from the diseases to which they become vulnerable during menopause, as well as its discomforts. If the conventional medical practitioners do not hear exactly what modern women want, the complementary medicine community does. Turning to centuries-old botanicals, they have validated and compounded them with new technology. Their effectiveness depends on various factors including the synergistic interaction of several herbs, specific preparation, the correct plant part and dosage, harvesting and manufacturing techniques.

Research demonstrates that plant hormones (phytoestrogens) protect against stronger potentially carcinogenic forms of estrogen while safely providing a hormone effect. Other herbs act more like tonics, zipping up the body's overall function.

Help From Herbs

Clinical trials and scientific processing techniques have resulted in plant-based supplements like soy and other botanicals that replicate the form and function of a woman's own estrogen.

The complementary community also can take credit for pushing the conventional medical community to look beyond estrogen to progesterone in postmenopausal health.

Natural soy or Mexican yam derived progesterone is formulated by pharmacologists in creams or gels that prevent estrogen-induced overgrowth of the uterine lining (a factor in uterine cancer), protect against heart disease and osteoporosis and reduce hot flashes (Fertility and Sterility 69, 1998: 96-101).

A quarter of the women who take the popularly prescribed synthetic progesterone report increased tension, fatigue and anxiety; natural versions have fewer side effects.

These "quasi-medicines," as Tori Hudson, a leading naturopathic doctor and professor at the National College of Naturopathic Medicine, Portland, Oregon, calls them, are considered "stronger than a botanical but weaker than a medicine." (Hudson is author of Gynecology and Naturopathic Medicine: A Treatment Manual.)

According to Hudson, the amount of estrogen and progesterone in these supplements is much less than medical hormone replacement but equally efficacious in relieving menopausal problems and protecting the heart and bones.

According to a study led by Harry K. Genant, PhD, of the University of California, San Francisco, "low-dose" plant estrogen derived from soy and yam, supplemented with calcium, prevents bone loss without such side effects as increased vaginal bleeding and endometrial hypoplasia, abnormal uterine cell growth that could be a precursor to endometrial cancer (Archives of Internal Medicine 157, 1997: 2609-2615).

These herbal products, including natural progesterone and estrogen in the form of the weaker estriol or estrone, may block the effect of the stronger and potentially DNA-damaging estradiol.

Soy in its myriad dietary and supplemental forms provides a rich source of isoflavones and phytosterols, both known to supply a mild estrogenic effect that can stimulate repair of the vaginal walls (Journal of the National Cancer Institute 83, 1991: 541-46).

To enhance vaginal moisture, try the herb cimicifuga racemosa, the extract of black cohosh that, in capsule form, builds up vaginal mucosa (Therapeuticum 1, 1987: 23-31). Traditional Chinese herbal formulas containing roots of rehmannia and dong quai have long been reputed to promote vaginal moisture.

Clinical research in Germany also confirms the usefulness of black cohosh in preventing hot flashes and sweating, as well as relieving nervousness, achiness and depressed moods caused by suppressed hormone levels. It works on the hypothalamus (the body's thermostat, appetite and blood pressure monitor), pituitary gland and estrogen receptors. Green tea is steeped with polyphenols, mainly flavonoids, that exert a massive antioxidant influence against allergens, viruses and carcinogens. The risks of estrogen-related cancers such as breast cancer are particularly lowered by these flavonoids, as these substances head directly to the breast's estrogen receptors. About three cups a day exert an impressive anti-inflammatory, antiallergenic, antiviral and anticarcinogenic effect.

Other phytoestrogen-rich botanicals, according to Susun Weed's Menopausal Years: The Wise Woman Way (Ash Tree Publishing), include motherwort and lactobacillus acidophilus to combat vaginal dryness; hops and nettles for sleep disturbances; witch hazel and shepherd's purse for heavy bleeding; motherwort and chasteberry for mood swings; dandelion and red clover for hot flashes.

Our Need For Supplements

Adding micronutrients at midlife to correct and counter a lifetime of poor diet and other habits is a step toward preventing the further development of the degenerative diseases to which we become vulnerable. At the very minimum, you should take:

a multivitamin/mineral supplement vitamin E calcium

Your multivitamin/mineral should contain vitamins A, B complex, C, D, E, calcium, magnesium, potassium, copper and zinc. Look for a wide variety of antioxidants that safeguard you from free radical damage, believed to promote heart disease and cancer, as well as contribute to the aging process.

Also on the list: mixed carotenoids such as lycopene, alpha carotene and vitamin C; and folic acid to help regulate cell division and support the health of gums, red blood cells, the gastrointestinal tract and the immune system.

Studies indicate a deficiency of folic acid (folate) in 30% of coronary heart disease, blood vessel disease and strokes; lack of folate is thought to be a serious risk factor for heart disease (OB.GYN News, July 15, 1997, page 28).

Extra vitamin E is believed to protect against breast cancer and bolster immune strength in people 65 and older (Journal of the American Medical Association 277, 1997: 1380-86). It helps relieve vaginal dryness, breast cysts and thyroid problems and, more recently, hit the headlines as an aid in reducing the effects of Alzheimer's and heart disease. It is suspected to reduce the thickening of the carotid arterial walls and may prevent the oxidation of LDL (bad) cholesterol, which contributes to the formation of plaque in arteries.

Selenium also has been identified as an assistant in halting cancer (JAMA 276, 1996: 1957-63).

The Omegas To The RESCUE

Essential fatty acids found in cold water fish, flaxseed, primrose and borage oils and many nuts and seeds are essential for the body's production of prostaglandin, biochemicals which regulate hormone synthesis, and numerous physiological responses including muscle contraction, vascular dilation and the shedding of the uterine lining. They influence hormonal balance, reduce dryness and relieve hot flashes.

In addition, the lignans in whole flaxseed behave like estrogen and act aggressively against breast cancer, according to rat and human studies at the University of Toronto (Nutr Cancer 26, 1996: 159-65).

Research has demonstrated that these omega-3 and omega-6 fatty acids can reverse the cancer-causing effects of radiation and other carcinogens (Journal of the National Cancer Institute 74, 1985: 1145-50). Deficiencies may cause swelling, increased blood clotting, breast pain, hot flashes, uterine and menstrual cramps and constipation. Fatigue, lack of endurance dry skin and hair and frequent colds may signal EFA shortage. Plus, fatty fish oils, along with vitamin D and lactose, help absorption of calcium, so vital for maintaining bone mass.

In addition, studies show that the natural substance Coenzyme A may help menopausal women reduce cholesterol and increase fat utilization (Med Hyp 1995; 44, 403, 405). Some researchers belive Coenzyme A plays a major role in helping women deal with stress while strengthening immunity.

Still Suffering?

Can't shake those menopausal woes? Menopause imposters may be imposing on you: The risk of thyroid disease, unrelenting stress, PMS, adrenal burnout, poor gastrointestinal health and hypoglycemia all increase at midlife. Menopause is a handy hook on which to hang every misery, ache and pain but it may only mimic the distress of other ailments. For this reason every midlife woman should have a good medical exam with appropriate tests to determine her baseline state of health. Only with proper analysis can you and your health practitioner hit on an accurate diagnosis and satisfying course of therapy.

And if menopause is truly the issue, you have plenty of company. No woman escapes it. No woman dies from it. It is not a disease but a reminder that one-third of life remains to be lived. Menopausal Baby Boomers can anticipate tapping into creative energy apart from procreation. If not new careers, new interests await. An altered internal balance empowers a menopausal woman to direct, perhaps for the first time, her experience of life. She has come of age-yet again. Gone is the confusion, uncertainty, or dictates of a hormone driven life: This time wisdom and experience direct her. There is no need to yearn for youth or cower at the conventional covenant of old age. Menopause is the clarion call to reframe, reevaluate and reclaim.

Mary Ann Mayo and Joseph L. Mayo, MD, are authors of The Menopause Manager (Revell) and executive editors of Health Opportunities for Women (HOW). Telephone number 877-547-5499 for more information.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=330)

Date: June 10, 2005 10:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbs in Perspective

Herbs in Perspective by Phyllis D. Light, RH-AHG Energy Times, June 16, 2004

"I don't claim a cure...I just try to give people some ease," noted Tommie Bass, a traditional Southern herbalist whose life has been the topic of several books, including Mountain Medicine by Darryl Patton (Natural Reader Press) and Trying to Give Ease by John Crellin and Jane Philpott (Duke University Press). That philosophy reflects the perspective embraced by herbalists for eons.

The traditional use of herbs is incorporated into all cultures. Herbs were the first medicine and the origin of what we now call modern medicine. These plants have not been prescribed to conquer specific illnesses but instead nourish the body and aid in building overall health.

Traditional Knowledge

Observation, psychological need and human instinct form the foundation of traditional herbal knowledge and use. This knowledge has been passed down through generations based on practice and experience. The result: a depth of information about the safe and effective use of herbs that spans thousands of years.

The goal of a traditional herbalist is to bring the body into balance (homeostasis), prevent disease and support immune functioning. Unfortunately, any kind of therapeutic knowledge can be misused, and that has happened with some herbs, causing some people to question herbal medicine's safety.

As more people turn to natural therapies, scientists have begun to perform evidence-based research into their safe and effective use. The good news is that much of this research has validated the effectiveness of herbs and supplements.

Echinacea to the RESCUE

Do the sniffling sneezes that herald a cold have you reaching for your bottle of echinacea? If so, you are in good company. Echinacea (Echinacea spp) is one of the top-selling herbs.

The colorful American prairie plant was extremely popular during the early 1900s, until the use of modern antibiotics relegated it to the back shelf. But a resurgence of interest in herbs propelled echinacea back into the mainstream in the second half of the twentieth century. And this herb boasts an impressive body of research and has an excellent record of safety.

For instance, researchers at Virginia Commonwealth University School of Pharmacy have found echinacea to be effective in supporting the body's defenses against upper respiratory tract infections and for reducing the duration of discomforts that accompany the common cold (Pharmacotherapy 2000; 20(6):690-7).

Although studies have not confirmed its ability to prevent colds, echinacea is widely used by many folks for just that purpose. Researchers have found that echinacea's effectiveness may drop if you use it for eight straight weeks (Am J Health-Syst Pharm 1999; 56(2):121-2). So if you take it for a couple of months, take a couple of weeks off before using it again.

Flower Power

St. John's wort is another herb with ancient origins that has experienced a modern resurgence. Named after St. John the Baptist, St. John's wort (Hypericum perforatum) is generally in bright yellow bloom around St. John's Day (June 26). According to herbalist Michael Tierra, author of The Way of Herbs (Pocket Books), St. John's wort affects the liver and the nervous system. In 1984, the German Commission E, a recognized herbal authority, approved St. John's for depressive disorders, and in topical form for acute injuries and first-degree burns.

Modern research has reaffirmed the use of St. John's wort in the short-term treatment of mild to moderate depression (Cochrane Review Issue 2, 2004). It has also been found to be useful in premenstrual depression (Int J Psy Med 2003; 33(3):295-7). (Researchers have found that the herb may alter how the body processes some prescription medications, so check with your healthcare provider before using such medicines along with St. John's wort.)

King of Herbs

" Ginseng (Panax) received the lofty title, King of Herbs, due to its reputation as a tonic and its ability to stimulate the body into healing," notes herbalism writer Darryl Patton. This plant was once so popular in China that it was worth its weight in gold.

In fact, ginseng is the popular name for two different types of ginseng, American and Korean (Panax quinquefolium and P. ginseng). Both are considered adaptogens, or substances that help the body deal with stress more effectively. And modern research has found that ginseng can be used to improve overall energy and vitality, and to help the body deal more effectively with chronic stress (J Pharm Sci 2003 Dec: 93(4):458-64).

Researchers have found that ginseng helps boost the immune system (J Med Food 2004 Spring; 7(1):1-6). This ancient herb is also a powerful antioxidant that confers protection on the heart (Biochem Biophys Acta 2004 Feb 24; 1670(3):165-71). In other studies, ginseng has been found to reduce symptoms of menopause, improve endurance and lower blood sugar levels. To avoid overharvesting wild ginseng, most of the herb on the market is now grown on farms.

Ode to Ginkgo

Known as the Living Fossil, ginkgo is the oldest known plant in the world. A native of Asia, ginkgo (Ginkgo biloba) is now found in many US cities, where it has been planted as a quick-growing shade tree. Traditionally, ginkgo was used for disorders and diseases of the lungs and the kidneys, as a remedy for bronchitis and to improve circulation in older people.

Ginkgo contains substances that act as potent antioxidants by scavenging cell-damaging free radicals, and it is thought to help reduce the risk of disease. By opening capillaries, ginkgo increases circulation, and enables nutrients and oxygen to move around the body, especially to the extremities.

Indeed, recent research indicates that ginkgo may ease pain associated with arterial disease in the legs (Am J Med 2000; 108:276-81). Other studies support the use of ginkgo for acute stress (J Pharm Sci 2003 Dec; 93(4):458-64) and some cases of hearing loss (Acta Otolaryngol 2001; 121:579-84).

In a UCLA Neuropsychiatric Institute study on ginkgo, researchers found significant improvement in the verbal recall of people who had age-related memory problems. According to Dr. Linda Ercoli, lead author of the study, "Our findings suggest intriguing avenues for future study...with a larger sample to better measure and understand the impact of ginkgo on brain metabolism."

Tasty Ginger

Traditionally, fiery ginger (Zingiber officinale) has been used to aid digestion, reduce nausea, relieve gas, reduce symptoms of arthritis and strengthen the heart. Modern researchers have started to validate these traditional uses; ginger has reduced the nausea and vomiting of morning sickness in studies (Aust NZJ Obstet Gynaecol 2003 Apr; 4392:139-44).

Meanwhile, researchers at the University of Minnesota have applied for a patent on a substance found in ginger, believing it to have anticancer activity. According to Ann Bode, "Plants of the ginger family have been credited with therapeutic and preventive powers and have been reported to have anticancer activity."

Ginger can be found in natural food stores as fresh or dried root. It often appears in small amounts in herbal formulas as a carrier herb-one that helps move other herbs around the body.

The best medicine combines the health support of herbs with the scientific rigor of conventional medicine. And as scientists continue to search for new medicine from ancient remedies, we can enjoy the best of both perspectives.

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Vitanet ®

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Date: June 10, 2005 05:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Allergy Alleviation

Allergy Alleviation by Cal Orey , February 2, 2002

Allergy Alleviation By Cal Orey

Welcome to the stuffed up world of seasonal allergic rhinitis: the wheezing, sneezing "inhalant allergies" that torment 35 million Americans. Adding insult to sinus pain, other allergens attack year-round. Air pollution, dust mites (microscopic gremlins that infest bedding, upholstery and rugs) and animal dander trigger allergies-or other respiratory ailments-in any season. Urban air is full of rubber tire particles, a true blowout for those with latex sensitivity. Altogether, roughly 50 million Americans-about one in five-suffer from some form of allergy, according to the American Academy of Allergy, Asthma and Immunology (AAAAI). Tired of cross-pollinating with plants or being bowled over by dust balls? Vitamins, herbs and other nutrients can help you nip allergy discomfort in the bud.

The Allergy Response

Your immune system triggers an allergic response when it overreacts to otherwise harmless substances or antigens (we're talking dust, pollen and mold).The alarmed immune system then launches a defensive chemical reaction, releasing potent chemicals (antibodies) supposed to destroy the "invaders." The antibodies, called IgE, carry the invading substances to special cells, which zap them with more biochemicals. Among these protective cells are mast cells: they release histamine, the substance that causes swelling and inflammation to the linings of the nose, sinuses and eyelids, resulting in sneezing, upper respiratory congestion and itchy, watery eyes.

Just Blame The Folks

Most allergies are determined by your genes. If your Mom or Dad sneeze and scratch, there's a good chance you will, too. "That is not to say that we directly inherit an allergy to any specific substance. Rather, it seems as if we might inherit some kind of immune system defect or weakness that leaves us more vulnerable to allergies," explain co-authors Glenn S. Rothfeld, MD, and Suzanne LeVert in their book Natural Medicine for Allergies: The Best Alternative Methods for Quick Relief (Rodale). For some people, allergies lurk in food, throwing the immune system into overdrive. "Many natural medicine practitioners believe that a diet high in animal fats will contribute to the development of allergy and asthma, as does a diet high in food additives, such as preservatives and dyes," says Gary McLain, PhD, in his book The Natural Way of Healing: Asthma and Allergies (Dell). Worse, allergies can up the risk of asthma, which afflicts 15 million Americans. Most people afflicted with asthma also suffer allergies: the two are linked, according to the AAAAI. Allergy triggers of asthma include pollen, mold spores and house dust mites. Remember Helen Hunt's asthmatic son in the movie As Good As It Gets? His character endured allergies to dust, and living in New York (and watching his mom date Jack Nicholson) didn't help his immune system. Coughs, ear infections, fevers and visits to hospital emergency rooms curtailed his social life (and limited his close-ups as well). That kind of routine happens in real life, too. (Well, maybe close encounters with Jack N. are not included for most.) But when we breathe substances such as molds, they can induce swelling and inflammation of the bronchial airways which narrow and restrict air flow. This, in turn, causes wheezing and shortness of breath and can trigger an asthma "attack," according to Andrew Engler, MD, who specializes in allergy and asthma in San Mateo, California.

The Nose Knows: Chemical Sensitivities

Imagine a picture-perfect, crisp, clear Saturday morning. You make a final stop on your weekly errand run to the dry cleaner, where you drop off your laundry and spend a moment chatting up the owner. Back in your car, your eyes tear and you feel a bit woozy. Kenneth Bock, MD, and Nellie Sabin, writing in The Road to Immunity: How To Survive and Thrive in a Toxic World (Pocket Books) sense that your reaction could be chemical sensitivity, a difficult to diagnose but, in their opinion, very real malady. (Of course, a clinician can test you for immune responses to certain chemicals.) Reactions to chemicals produce the typical allergic responses: puffy or red-rimmed eyes; swelling; aching or stiff joints and muscles; irritability or dizziness; respiratory inflammations; headaches and the like. Villains include aerosol sprays, tobacco smoke, glues, insecticides and herbicides, household chemicals and fragrances. Identification and avoidance are key, say the authors. Vitamin C, which binds with chemicals, is one of the best nutritional defenses.

Breathing Problems Expand

Americans now freely take lifesaving medicines such as antibiotics and insulin but, in some people, "they have the potential to alter the immune system, which is where allergies begin," says Dr. McLain. (Consult your pharmacist if you have questions about your prescription medication.) We, as a nation, are also eating more chemicals, from the pesticides drenched on plants to the preservatives poured on prepared foods. We're breathing polluted air, which can lead to or exacerbate asthma, and then we choke on recycled air in sealed buildings. And while a century ago you were likely to have spent much of your time close to home, you can now hop on a supersonic plane and be taken to the other side of the globe within a matter of hours. With travel comes exposure to even more exotic allergens that can drive your immune system to distraction.

The All-Natural Gesundheit

Certain allergy-relief nutrients and herbs can help make life more bearable. Here's how they work: n Vitamin C for the lungs. According to experts, when vitamin C is low, asthma is high. Vitamin C carries the major antioxidant load in the airways and therefore contributes mightily to the health of the lungs. A study in the Annals of Allergy (73(1994):89-96) reported that in seven of 11 clinical trials since 1973, vitamin C supplementation provided "significant improvements" in respiratory function and asthma symptoms. n Vitamin E and carotene to suppress allergic reactions. These antioxidants may also help protect the respiratory tract from caustic pollutants. Vitamin E is reputed to be one of the most important nutrients for antioxidant protection in the lungs. In addition, these two substances decrease production of allergy-related compounds called leukotrienes. n Zinc for the immune system. Research shows that a deficiency in this trace mineral can weaken your immune system, setting you up as a target for allergies and infections. (Some vegetarians may not store sufficient amounts of this mineral and should take supplements.) Zinc comes to the body's RESCUE by taking part in the production of IgA, the gastrointestinal antibody that lines the digestive tract. "When IgA binds to an allergen, it keeps it from being absorbed into the bloodstream and thus from causing an allergic reaction," report Rothfeld and Levert. Also, zinc protects mucous membranes and helps convert beta carotene to vitamin A, another anti-allergy, immune-boosting nutrient. In a study of 100 participants at the Cleveland Clinic Foundation, half took a zinc-based lozenge, while the other half received a dummy preparation. The participants taking zinc experienced a 42% reduction in the duration and severity of their common colds (Annals of Internal Medicine, 7/96). n Quercetin as an antihistamine. A valuable, anti-allergic flavonoid (plant coloring agent that is a powerful antioxidant), quercetin shines as a potent weapon against allergies and asthma. Believed to inhibit histamine release from mast cells and slow the production of other allergy-related compounds, it stabilizes mast cell membranes. Other flavonoid-rich extracts include grape seed, pine bark, green tea and Ginkgo biloba. n Additional helpful nutrients: Vitamin B-12, particularly to combat sensitivity to sulfites (The Nutrition Desk Reference [Keats]); selenium, an antioxidant that breaks down leukotrienes (Clinical Science 77, 1989: 495-500); and magnesium to relax bronchial tissues (Journal of the American Medical Association, 262 [1989]: 1210-3).

Herbal Remedies To The RESCUE

n Nettles for hay fever relief. Research at the National College of Naturopathic Medicine in Portland, Oregon, showed that 40 of 69 folks suffering from hay fever found moderate to extreme relief from taking freeze-dried stinging nettles (Planta Medica, [1990] 44-47). "It is nontoxic, cheap and preferable to antihistamines, which I think are significantly toxic," reports Andrew Weil, MD, in his book Natural Health, Natural Medicine: A Comprehensive Manual for Wellness and Self-Care (Houghton Mifflin). n Cayenne to reduce inflammation. Cayenne, known as hot red pepper, is rich in capsaicin, a potent flavonoid "counter-irritant" that dilates and soothes inflamed nasal and bronchial tissues, according to experts. A bonus: Cayenne also contains a rich amount of antioxidant vitamin C, which can help enhance your immune system. n Echinacea for allergy prevention. This popular Native American herb provides cold and allergy protection, particularly when you take it before encountering allergens. Studies reveal that echinacea aids your body's tissues and protects you from germs and allergens. In fact, German studies have found it possesses valuable antiviral, antibacterial and immunity-boosting properties.

Make Your World Allergy-Free

For the most effective allergy relief, make sure you stay clear of allergens that wreak allergy havoc. Visit an allergy-savvy health practitioner and get tested to find out which substances rock your respiratory world. Plus, allergy experts recommend: n Banish dust mites: sweep out clutter and have your house power-vacuumed, if necessary; wash bedding and linens in very hot water. n De-pollinate your environment: flip on the air conditioner to sift out pollen (keep its filter and any forced air registers clean); exercise indoors; machine dry, rather than line dry, your clothes. n Buy a home air filter, especially if you experience dust, pollen or pet dander allergies. n Avoid allergy triggers that dog your days: cats and canines (or consider the hairless or shed-less breeds), mold and tobacco smoke. No matter what you do or actions you take, allergies may always remain an annoyance in your life. But attention to the foods you eat, the places where you exercise and the right combination of anti-allergy nutrients can limit your discomfort.

Leveling The Leukotrine Playing Field

On a microscopic level, a series of biochemicals implicated in allergic reactions are leukotrienes, substances that may constrict the bronchial tubes (breathing passages). In some people, consuming the food additive tartrazine can cause severe asthmatic breathing difficulties by boosting leukotrine release. In turn, this can interfere with the body's use of vitamin B-6. The process in which lack of B-6 or "errors" in how your body uses B-6 causes allergic reactions and is complex. According to Michael Murray, ND and Joseph Pizzorno, ND in the revised edition of the Encyclopedia of Natural Medicine (Prima), breathing problems may begin when the metabolism of tryptophan (an amino acid) goes awry: "Tryptophan is converted to serotonin, a compound that, among other things, can cause the airways of asthmatics to constrict...Vitamin B-6 is required for the proper metabolism of tryptophan." Accordingly, a study of vitamin B-6, published in the American Journal of Clinical Nutrition, shows that people with compromised breathing may possess less B-6 in their blood than others who breathe normally. When people with asthma were given B-6, their wheezing and asthmatic attacks dropped.

Fat Fix For Allergies

The fat in your diet or supplements can also influence your susceptibility to allergies and asthma linked to allergies. Epidemiologists have found that countries where children eat fish at least four times a month cut their risk of asthma by 67% compared to other parts of the world where they consume fewer fish. Research on omega-3 fatty acids, the kind of fat found in fish, flax and hemp oil, demonstrates that some of these substances can improve breathing. In particular, fatty acids called eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can help open up bronchial tubes. Studies in the American Review of Respiratory Disease and the International Archives of Allergy and Applied Immunology show that breathing passageways may not react so negatively to the presence of allergens when you eat more fish or take supplements containing these types of fats. Many of the scientists who study the kinds of fats we eat believe that the increase in allergies and asthma in the US during the twentieth century may be due to both increasing air pollution (which irritates our lungs) plus a simultaneous increase in our consumption of what are called omega-6 fatty acids. Omega-6 oils are contained in most of the vegetable oils Americans eat, including sunflower and peanut oils. While experts believe that we would be better off consuming a diet containing about five times as many omega-6 fatty acids as omega-3s, today we eat about 40 times as much omega-6s. The chemistry of how these fats influence our allergy susceptibility is complex. It begins in our cell membranes which consist mostly of fat. When we consume omega-3 fatty acids, in our diet or in supplements, and these fats enter cell membranes, the change in structure cuts the availability of arachidonic acid, a fatty acid your body can make and which is found in meat, eggs and dairy products. Eventually, it is thought that this change in cellular metabolism and reduction in arachidonic acid forces the body to make less 4-series leukotrienes, substances which are quite prone to provoking allergic inflammation and, instead, produce 5-series leukotrienes, leukotrienes which don't cause nearly as much trouble. This process requires patience. According to Pizzorno and Murray. "It may take as long as one year before the benefits are apparent, as it appears to take time to turn over cellular membranes in favor of the omega-3 fatty acids."

Chinese Medicine Versus Allergies

Traditional Chinese Medicine (TCM) views allergies as an imbalance of the liver, says Jason Elias, co-author with Katherine Ketcham of The Five Elements of Self-Healing (Harmony Books). "The average American's (liver) deals with about fourteen pounds of chemicals a year. What would normally be a minor irritant becomes major because the liver can't process them anymore," explains Elias. Licorice root (Glycyrrhiza glabra) has traditionally been used to fight allergies since this herb battles inflammation as evidenced by Japanese research and a study published in the journal Allergy. Much of this anti-allergy action is thought to proceed from licorice's interaction with a biochemical called cortisol, a hormone secreted by the adrenal glands. Cortisol (along with epinephrine, another adrenal hormone) relaxes the muscles controlling airways. By slowing the liver's breakdown of cortisol, licorice prolongs circulation of this hormone which, in turn, can help breathing passages stay clear. In addition, glycyrrhetinic acid, a compound in licorice, slows the body's manufacture of prostaglandins and leukotrienes, substances which exacerbate allergic inflammatory reactions. Ma Huang (Ephedra sinica) has been employed for thousands of years to aid breathing since chemicals in this plant widen breathing passages.

Homeopathic Remedies for Allergy

Homeopathic treatments consist of highly diluted substances designed to coax the body into healing itself. The effectiveness of homeopathy for hayfever has been demonstrated by research published in Lancet performed at the University of Glasgow, Scotland. There, scientists showed that homeopathically-prepared medicines produced statistically significant improvements in allergy sufferers. The appropriate homeopathic remedy for any illness depends on the personality type of the person suffering an allergy. These treatments are among those recommended by Dana Ullman: n Allium cepa: appropriate for burning nasal discharge that grows worse in warm rooms and improves outdoors. Relieves non-burning tearing from eyes, raw feeling in the nose with tingling sensation and violent sneezing. n Nux vomica: used when feeling irritable and chilled, with daytime fluent nasal discharge and night congestion that grows worse indoors. Also for those sensitive to cold and to being uncovered. n Pulsatilla: best for women and children with daytime nasal discharge and night congestion who are gentle, yielding, mild, impressionable and emotional. Used when congestion is worse in warm rooms, hot weather or while lying down.

Food Allergy Conundrum Food allergies can prove to be the toughest allergies to identify and eliminate. Jason Elias believes that people may develop food sensitivities from eating the same foods too often. "If someone has an allergy, I might say 'Let's get you off dairy for three weeks,'" he says, noting that some people have limited their hay fever problems by ceasing to consume dairy products. Many have also found relief by maintaining a food diary, keeping track of which foods are associated with allergy attacks and then eliminating those foods. So the next time you sneeze, don't just reach for your hanky, think back to the meal that you just ate. Your allergy problem may be sitting in your stomach as well as making you sneeze and stuffing your sinuses. Taking these kinds of anti-allergy preventive measures can provide life-enhancing relief that feels like a godsend. That lets you attain your healthy best.

This article included reporting by Judy Pokras.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=278)

Date: May 13, 2005 09:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Important Information for Allergy Sufferers

Important Information for Allergy Sufferers

Imagine you are one among millions who greet each spring with worry about the flood of pollen that fills the air this time of year. When the pollen season arrives, as it inevitably does, you find yourself with two choices. You can either take over-the-counter antihistamines and put up with unpleasant side-effects, or endure the sneezing, runny nose, itchy, watery eyes and other discomforts of hay fever.

If there was a natural ingredient, a nutritional substance found throughout nature in many foods and plants, that could offer an alternative, would you not be interested?

Quercetin, one among hundreds of flavonoids found throughout the plant kingdom, is this ingredient. Quercetin has been researched in numerous pharmacological studies. The results of this work strongly suggest that quercetin helps to stabilize the fundamental process in the body which causes an allergic reaction. Quercetin, as shown in test-tube ("in vitro") studies, prevents the release of histamine from "mast cells," immune cells that stand guard in the tissues which meet the outside environment—the nasal passages, the lungs, the digestive tract and skin. While this has yet to be confirmed by human clinical trials, in the picture that emerges from the research so far, quercetin looks like a RESCUE nutrient for allergy sufferers.

Reports from Quercetin Users

I have seen numerous reports from individuals who have indeed achieved significant reductions in allergic sensitivity by using quercetin. And this includes food allergies as well as environmental allergies. Anecdotal stories like these carry little weight among scientists, because they do not provide evidence that the observed result will be repeated in other cases. Only placebo-controlled, double-blind studies can produce this kind of scientific proof. Yet, when anectodal evidence (this includes physician "case reports") correlates with the results of pharmacological research such as we have on quercetin, I believe it should be taken seriously. And quercetin is a nutrient that works effectively when taken as a dietary supplement.

For example, one gentleman writes that his wife, who is allergic to pollen and dust, is now "sneeze-free" after using quercetin for three years. A Pennsylvania woman writes that her husband, also a long time allergy sufferer, "seems to be nearly allergy free" after one month of use. Another man says that "quercetin has literally changed my life." These are not isolated cases; a respected nutritionist who specializes in allergies and environmental problems has seen many similar outcomes with a quercetin. Clearly something significant is going on with respect to quercetin as a nutritional approach for overcoming allergies.

Bear in mind, though, that quercetin does not function like an antihistamine medication; it is not a quick fix. As a nutrient that helps to normalize body functions naturally, quercetin needs time to work, and should be taken for at least two or three weeks to achieve these results.

Quercetin Quiets the Allergic Response

Exerting a broad range of biological effects, quercetin is perhaps the most active and versatile flavonoid. In test-tube studies, quercetin acts directly on the mast cell in a way that quiets the allergic response.

An allergic reaction occurs when IgE antibodies, positioned on the mast cell surface, come in contact with a potential allergy-causing substance like pollen. The mast cell is then signaled to release histamine from storage granules located inside the cell, through a process called "degranulation." The histamine circulates throughout the body, causing the runny nose, itching and other discomforts associated with allergies.

Quercetin stabilizes mast cell membranes, in effect turning down the allergic response signal. Quercetin also slows other mechanisms which are involved with inflammation, such as the production of inflammatory prostaglandins and leukotrienes. This adds to its membrane-stabilizing effect, and its value in allergy control.

Quercetin appears to substantially raise the threshold for initiation of an allergic reaction. In allergy sufferers this threshold is low, for reasons which are not well understood. They may have more IgE antibodies than normal, making the mast cells overly "trigger happy." Histamine has its proper place in the immune response that defends us against truly harmful foreign substances in the body. But like many chemicals produced by the body, histamine is a two-edged sword. In allergy-prone individuals, the mast cells have become overreactive, releasing too much histamine, unnecessarily. With quercetin in the bloodstream, histamine release from mast cells is kept under control. Quercetin's ability to down-regulate both the inflammatory and allergic responses makes it, I believe, a highly important nutrient for humans to consume on a regular basis.

Quercetin-the Scientific Evidence

Several studies, published in respected journals such as the Journal of Allergy and Clinical Immunology and others, have demonstrated quercetin's ability to control the release of histamine from mast cells. (Quercetin has the same effect on basophils, a type of white blood cell that also contains histamine.) In these experiments, mast cells taken from both animals and humans are exposed in the test tube to various substances—called "antigens"— that stimulate histamine release. The researchers then add an inhibiting agent such as quercetin to the mixture and measure the differences in histamine output. Quercetin has shown itself to be one of the more powerful histamine inhibitors, more powerful, in fact, than disodium cromoglycate, an anti-asthma drug.

Quercetin has other beneficial properties. A strong antioxidant, Quercetin has a higher level of antioxidant activity than both vitamin C and vitamin E. (Quercetin enhances the antioxidant activity of vitamin C; quercetin and vitamin C are true synergists.) Quercetin has been shown to block the oxidation of LDL cholesterol by free radicals. Quercetin also protects cell membranes from being injured by oxidized LDL. The damage that oxidized LDL causes to the delicate membranes of blood vessel linings allows plaque deposits to form, setting the stage for atheroslcerosis. These observations point to quercetin as a key nutrient for maintaining cardiovascular health.

Like all flavonoids, quercetin is not classified as an essential nutrient, although flavonoids were once called "Vitamin P." In view of its many beneficial actions, quercetin is a nutrient that clearly has important roles to play in human nutrition, for allergy sufferers, and for everyone.